subject:(zpo d n argument)

Universidade do Rio Grande do Sul

1. Bock, Hugo. Perfil ontogenético da transcrição de subunidades do receptor N-Metil-D-Aspartato (NMDA) em estruturas cerebrais de ratos.

Degree: 2009, Universidade do Rio Grande do Sul

URL: http://hdl.handle.net/10183/18800

►

O glutamato (Glu) é o neurotransmissor excitatório mais abundante do sistema nervoso central e está envolvido em funções cerebrais como aprendizado/memória, desenvolvimento e envelhecimento cerebral.… (more)

▼

O glutamato (Glu) é o neurotransmissor excitatório mais abundante do sistema nervoso central e está envolvido em funções cerebrais como aprendizado/memória, desenvolvimento e envelhecimento cerebral. Mudanças na vulnerabilidade neuronal durante o desenvolvimento pós-natal podem ser parcialmente explicadas por mudanças na expressão das subunidades de receptores de Glu (GluRs). O objetivo desse trabalho foi determinar o padrão de expressão das subunidades de GluRs do tipo N-metil-D-aspartato (NMDA) em quatro estruturas cerebrais (cerebelo, córtex, estriato e hipocampo) em diferentes estágios do desenvolvimento pós-natal de ratos por quantificação relativa por PCR em tempo real. Mudanças significativas na expressão de Grin1 foram observadas em quase todas as estruturas em relação aos níveis pós-natais de expressão. Níveis de expressão de Grin2A foram menores no cerebelo com um padrão de aumento gradual e níveis elevados na vida adulta no córtex e no hipocampo. A expressão do Grin2B demonstrou um padrão decrescente no cerebelo assim como no hipocampo. Por outro lado, o padrão de expressão de Grin2C mostrou uma tendência a aumentar nas quatro estruturas, a qual foi mais evidente no cerebelo com um aumento significativo nos níveis de expressão. O padrão de expressão do Grin2D foi também caracterizado por uma tendência para uma diminuição nos níveis de expressão pela vida adulta. Essa tendência foi mais evidente no cerebelo e no hipocampo. Expressões de Grin3A e Grin3B não demonstraram uma tendência específica. No caso de Grin3B, níveis semelhantes de expressão foram observados com a exceção de um pico de expressão no cerebelo de ratos de 10 dias. Os dados obtidos nesse estudo permitiram-nos introduzir novos aspectos na área de expressão de GluRs e poderão contribuir para desvendar potenciais alvos para o desenvolvimento de terapias mais efetivas para muitas doenças.

Glutamate (Glu) is the most abundant excitatory neurotransmitter of the central nervous system and is involved in cerebral functions such as learning/memory, development, and cerebral aging. The changes in vulnerability of neurons during postnatal development can be partially explained by changes in expression of glutamate receptors subunits (GluRs). In this work, we aimed to determine expression profile of ionotropic Nmethil- D-aspartate (NMDA) GluR subunits in four brain structures (cortex, cerebellum, striatum and hippocampus) in different stages of postnatal rat development by relative quantification real-time PCR using glyceraldehyde 3-phosphate dehydrogenase (Gapdh) as endogenous control. Significant changes in Grin1 expression were demonstrated in almost each age from all structures in relation to the initial postnatal expression level. Levels of expression of Grin2A were lower in cerebellum with a gradual raising pattern and high levels in adulthood in cortex and hippocampus. Grin2B expression levels were found to show a decreasing pattern in cerebellum as well as in hippocampus. Conversely, Grin2C expression pattern was found to show an increasing…

Advisors/Committee Members: Pereira, Maria Luiza Saraiva.

Subjects/Keywords: Ratos; N-Metil-D-Aspartato

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Bock, H. (2009). Perfil ontogenético da transcrição de subunidades do receptor N-Metil-D-Aspartato (NMDA) em estruturas cerebrais de ratos. (Thesis). Universidade do Rio Grande do Sul. Retrieved from http://hdl.handle.net/10183/18800

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Bock, Hugo. “Perfil ontogenético da transcrição de subunidades do receptor N-Metil-D-Aspartato (NMDA) em estruturas cerebrais de ratos.” 2009. Thesis, Universidade do Rio Grande do Sul. Accessed January 20, 2021. http://hdl.handle.net/10183/18800.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Bock, Hugo. “Perfil ontogenético da transcrição de subunidades do receptor N-Metil-D-Aspartato (NMDA) em estruturas cerebrais de ratos.” 2009. Web. 20 Jan 2021.

Vancouver:

Bock H. Perfil ontogenético da transcrição de subunidades do receptor N-Metil-D-Aspartato (NMDA) em estruturas cerebrais de ratos. [Internet] [Thesis]. Universidade do Rio Grande do Sul; 2009. [cited 2021 Jan 20]. Available from: http://hdl.handle.net/10183/18800.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Bock H. Perfil ontogenético da transcrição de subunidades do receptor N-Metil-D-Aspartato (NMDA) em estruturas cerebrais de ratos. [Thesis]. Universidade do Rio Grande do Sul; 2009. Available from: http://hdl.handle.net/10183/18800

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Guelph

2. Broadfield, Lindsay. Combined Effects of N-3 Polyunsaturated Fatty Acids and 1alpha, 25-dihydroxyvitamin D on Breast Cancer Cell Growth.

Degree: MS, Department of Human Health and Nutritional Sciences, 2013, University of Guelph

URL: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/7413

► Omega-3 polyunsaturated fatty acids (PUFA) and vitamin D both have anti-cancer effects through common and unique pathways. The hypothesis of this thesis is that the… (more)

Subjects/Keywords: breast cancer; n-3 PUFA; vitamin D

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Broadfield, L. (2013). Combined Effects of N-3 Polyunsaturated Fatty Acids and 1alpha, 25-dihydroxyvitamin D on Breast Cancer Cell Growth. (Masters Thesis). University of Guelph. Retrieved from https://atrium.lib.uoguelph.ca/xmlui/handle/10214/7413

Chicago Manual of Style (16^th Edition):

Broadfield, Lindsay. “Combined Effects of N-3 Polyunsaturated Fatty Acids and 1alpha, 25-dihydroxyvitamin D on Breast Cancer Cell Growth.” 2013. Masters Thesis, University of Guelph. Accessed January 20, 2021. https://atrium.lib.uoguelph.ca/xmlui/handle/10214/7413.

MLA Handbook (7^th Edition):

Broadfield, Lindsay. “Combined Effects of N-3 Polyunsaturated Fatty Acids and 1alpha, 25-dihydroxyvitamin D on Breast Cancer Cell Growth.” 2013. Web. 20 Jan 2021.

Vancouver:

Broadfield L. Combined Effects of N-3 Polyunsaturated Fatty Acids and 1alpha, 25-dihydroxyvitamin D on Breast Cancer Cell Growth. [Internet] [Masters thesis]. University of Guelph; 2013. [cited 2021 Jan 20]. Available from: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/7413.

Council of Science Editors:

Broadfield L. Combined Effects of N-3 Polyunsaturated Fatty Acids and 1alpha, 25-dihydroxyvitamin D on Breast Cancer Cell Growth. [Masters Thesis]. University of Guelph; 2013. Available from: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/7413

East Tennessee State University

3. Swati, Swati. Cloning of N-acylethanolamine Metabolic Pathway Genes from Physcomitrella patens.

Degree: MS, Biology, 2017, East Tennessee State University

URL: https://dc.etsu.edu/etd/3178

► N-acylethanolamines (NAEs) including anandamide are lipid derivative molecules, which play vital roles in physiological and developmental processes in plants and animals and mediate stress… (more)

Subjects/Keywords: Anandamide; Fatty Acid Amide Hydrolase; N-acylethanolamine; N-acylphosphatidylethanolamine; N-acylphosphatidylethanolamine-Phospholipase D; N-acylphosphatidylethanolamine; Physcomitrella patens; Biology

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Swati, S. (2017). Cloning of N-acylethanolamine Metabolic Pathway Genes from Physcomitrella patens. (Thesis). East Tennessee State University. Retrieved from https://dc.etsu.edu/etd/3178

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Swati, Swati. “Cloning of N-acylethanolamine Metabolic Pathway Genes from Physcomitrella patens.” 2017. Thesis, East Tennessee State University. Accessed January 20, 2021. https://dc.etsu.edu/etd/3178.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Swati, Swati. “Cloning of N-acylethanolamine Metabolic Pathway Genes from Physcomitrella patens.” 2017. Web. 20 Jan 2021.

Vancouver:

Swati S. Cloning of N-acylethanolamine Metabolic Pathway Genes from Physcomitrella patens. [Internet] [Thesis]. East Tennessee State University; 2017. [cited 2021 Jan 20]. Available from: https://dc.etsu.edu/etd/3178.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Swati S. Cloning of N-acylethanolamine Metabolic Pathway Genes from Physcomitrella patens. [Thesis]. East Tennessee State University; 2017. Available from: https://dc.etsu.edu/etd/3178

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Ottawa

4. Villegas-Peñaranda, Luis Roberto. Production of Sialic Acid Analogs in Engineered E. coli: Characterization of Amino Sugar Recycling .

Degree: 2019, University of Ottawa

URL: http://hdl.handle.net/10393/39807

► This research focused on the study of the amino sugar recycling and sialic acid degradation pathway as a possible entry point for N-acyl glucosamines for… (more)

▼ This research focused on the study of the amino sugar recycling and sialic acid degradation pathway as a possible entry point for N-acyl glucosamines for the production of sialic acid analogs. Meeting this objective would allow the development of a bacterial strain capable of producing non-natural nonulosonic acids that could be used in the development of medicines, vaccines or useful compounds for the study of interactions between pathogenic organisms and their host. The first step was to understand how N-acetyl-D-glucosamine-6-phosphate deacetylase reacts to different types of substrates in order to determine its tolerance to the size of acyl groups in acyl amino sugars. This was achieved by studying the enzymatic activity in an in vitro system. We determine that the enzyme has a preference for small and slightly bulky acyl groups. Then, an in silico docking modeling and an in vivo system experiment were carried out. These experiments allowed to confirm the previous results. The second project was carried out due to the uncertainty of whether the kinase involved in the catabolic pathway would be able to phosphorylate the substrates. By quantifying residual ATP, the high specificity of N-acetyl-D-glucosamine kinase could be verified. This result led us to think about the design of an organic synthesis strategy that would allow the phosphorylation of glucosamine in carbon 6. A simple synthetic route was designed based on the protection of the two most reactive moieties of the amino sugars and the reactivity of the hydroxy group on carbon 6. However, we had problems with the purification step of the final product due to its high polarity. The next stage of this investigation was to confirm the transformation of GlcNAc into ManNAc. For this, an NMR analysis was designed that would detect the presence of both sugars in the reaction system. The epimerization of ManNAc to GlcNAc was detected successfully. Notwithstanding, the reverse reaction could not be detected. Based on the results obtained in the previous stage, we realized that an error was made in the epimerization reaction since we placed the wrong kinase because we did not take into account its substrate specificity. Finally, we tried to produce sialic acid analogs in a fermentative system using different genetic variants of Escherichia coli. Two of the expected analogs, Neu5Pr and Neu5nBu, were obtained. In addition, NagA activity towards substrates with small acyl groups was confirmed.

Subjects/Keywords: Sialic acid; Analogs; N-acetyl-D-glucosamine; N-acyl-D-glucosamine; NagA; Sialic acid analogs; Chemical phosphorylation; N-acetyl-D-glucosamine-6-P deacetylase

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Villegas-Peñaranda, L. R. (2019). Production of Sialic Acid Analogs in Engineered E. coli: Characterization of Amino Sugar Recycling . (Thesis). University of Ottawa. Retrieved from http://hdl.handle.net/10393/39807

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Villegas-Peñaranda, Luis Roberto. “Production of Sialic Acid Analogs in Engineered E. coli: Characterization of Amino Sugar Recycling .” 2019. Thesis, University of Ottawa. Accessed January 20, 2021. http://hdl.handle.net/10393/39807.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Villegas-Peñaranda, Luis Roberto. “Production of Sialic Acid Analogs in Engineered E. coli: Characterization of Amino Sugar Recycling .” 2019. Web. 20 Jan 2021.

Vancouver:

Villegas-Peñaranda LR. Production of Sialic Acid Analogs in Engineered E. coli: Characterization of Amino Sugar Recycling . [Internet] [Thesis]. University of Ottawa; 2019. [cited 2021 Jan 20]. Available from: http://hdl.handle.net/10393/39807.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Villegas-Peñaranda LR. Production of Sialic Acid Analogs in Engineered E. coli: Characterization of Amino Sugar Recycling . [Thesis]. University of Ottawa; 2019. Available from: http://hdl.handle.net/10393/39807

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

5. Carvalho, Silas Luiz de. Persistência de ordem em modelos ferromagnéticos na presença de campos auto-similares quase aleatórios\".

Degree: Mestrado, Física, 2007, University of São Paulo

URL: http://www.teses.usp.br/teses/disponiveis/43/43134/tde-02042008-144148/ ;

►

Neste trabalho estudamos a existência de ordem de longo alcance em modelos ferromagnéticos na presença de um campo externo cuja configuração apresenta um padrão tipicamente… (more)

▼

Neste trabalho estudamos a existência de ordem de longo alcance em modelos ferromagnéticos na presença de um campo externo cuja configuração apresenta um padrão tipicamente aleatório. Provamos por meio do argumento de Peierls modificado por Griffiths para o estudo de um antiferromagneto, que o modelo de Ising ferromagnético bidimensional exibe, para um campo alternado de intensidade fraca, ordem de longo alcance `a temperatura finita. Propomos dar um passo além considerando campos auto-similares esparsos, cuja soma é nula em todas as escalas. Estudamos também o modelo hierárquico em duas dimensões, para o qual provamos a existência de ordem de longo alcance a temperatura finita, na ausência de campo externo e para um campo com regiões irregulares esparsas. Provamos que os resultados do modelo de contornos hierárquicos são equivalentes aos resultados do modelo hierárquico em duas dimensões. Por fim, provamos através do método do limite infravermelho existência de ordem de longo alcance no modelo N-vetorial com campo alternado, de intensidade fraca, para d >= 3, sob a hipótese de que a variância do estado associado `a interação com o campo apresenta cardinalidade inferior a do volume do sistema. Mostramos, sob hipóteses similares, que o modelo N-vetorial hierárquico com campo externo, esparso e de intensidade pequena, apresenta ordem de longo alcance a baixas temperaturas.

In this work we study the existence of long range order for ferromagnetic models in the presence of an external field whose configuration has a pattern typically random. We prove, via the Peierlsárgument modified by Griffiths in his study of an antiferromagnet, that the two dimensional ferromagnetic Ising model for a staggered field exhibits long-range order at finite temperature and small field intensity. We propose to give a further step considering sparse self similar fields, whose sum is zero in all scales. We study as well the hierarchical model in two dimensions, where we prove existence of long-range order at finite temperature in the absence of external field and for a field configuration with sparse irregular regions. We prove that the results for the two-dimensional hierarchical contours model are equivalent to the results of the hierarchical model in two dimensions. Lastly, we prove via infrared bound method, existence of long range order in the N-vector model with a staggered and weak external field for d >= 3, under the hypothesis that the variance of the state connected with the field interaction has cardinality lower than volume. We show, under similar hypotheses, that the N-vector hierarchical model with a sparse field of low intensity has long range ordem at low temperatures.

Advisors/Committee Members: Marchetti, Domingos Humberto Urbano.

Subjects/Keywords: Argumento de Peierls; Dyson hierarchical model; Hierarchical contours model; Hierarchical N-vector model; Ising model; Long Range order; Modelo de contornos hierárquicos; Modelo Hierarquico de Dyson; Modelo ising; Modelo N-vetorial; Modelo N-vetorial hierárquico; N-vector model; Ordem de logo alcance; Peierls argument

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Carvalho, S. L. d. (2007). Persistência de ordem em modelos ferromagnéticos na presença de campos auto-similares quase aleatórios\". (Masters Thesis). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/43/43134/tde-02042008-144148/ ;

Chicago Manual of Style (16^th Edition):

Carvalho, Silas Luiz de. “Persistência de ordem em modelos ferromagnéticos na presença de campos auto-similares quase aleatórios\".” 2007. Masters Thesis, University of São Paulo. Accessed January 20, 2021. http://www.teses.usp.br/teses/disponiveis/43/43134/tde-02042008-144148/ ;.

MLA Handbook (7^th Edition):

Carvalho, Silas Luiz de. “Persistência de ordem em modelos ferromagnéticos na presença de campos auto-similares quase aleatórios\".” 2007. Web. 20 Jan 2021.

Vancouver:

Carvalho SLd. Persistência de ordem em modelos ferromagnéticos na presença de campos auto-similares quase aleatórios\". [Internet] [Masters thesis]. University of São Paulo; 2007. [cited 2021 Jan 20]. Available from: http://www.teses.usp.br/teses/disponiveis/43/43134/tde-02042008-144148/ ;.

Council of Science Editors:

Carvalho SLd. Persistência de ordem em modelos ferromagnéticos na presença de campos auto-similares quase aleatórios\". [Masters Thesis]. University of São Paulo; 2007. Available from: http://www.teses.usp.br/teses/disponiveis/43/43134/tde-02042008-144148/ ;

6. Pablo de Castro Santos. Atividade β-D-N-Acetilglucosaminidásica de enzimas imobilizadas extraídas da Artemia franciscana e possíveis aplicações biotecnológicas.

Degree: 2008, Universidade Federal do Rio Grande do Norte

URL: http://bdtd.bczm.ufrn.br/tedesimplificado//tde_busca/arquivo.php?codArquivo=2284

►

A β-D-N-acetilglucosaminidase extracted and partially isolated from crustacean Artemia franciscana by ammonium sulfate precipitation and filtration gel chromatography Bio Gel A 1.5m. the enzyme was… (more)

▼

A β-D-N-acetilglucosaminidase extracted and partially isolated from crustacean Artemia franciscana by ammonium sulfate precipitation and filtration gel chromatography Bio Gel A 1.5m. the enzyme was immobilized on ferromagnetic Dacron yielding a insoluble active derivative with 5.0 units/mg protein and 10.35% of the soluble enzyme activity. β-D-N-acetilglucosaminidase-ferromagnetic Dacron was easily removed from the reaction mixture by a magnetic field, it was reused for ten times without loss in its activity. The ferromagnetic Dacron was better activated at pH 5.0. The particles visualized at scanning electron microscope (SEM) had presented different sizes, varying between 721nm and 100m. Infra red confirmed immobilization on support, as showed by primary amino peaks at 1640 and 1560 cm-1 . The immobilize enzyme presented Km of 2.32 0.48 mM and optimum temperature of 50C. Bought presented the same thermal stable of the soluble enzyme and larger enzymatic activity at pH 5.5. β-D-N-acetilglucosaminidase-Dacron ferromagnético showed sensible for some íons as the silver (AgNO3), with loss of activity. The β-D-N acetilglucosaminidase activity for mercury chloride (HgCl2), whom is one of the most toxic substance joined in nature, it was presented activity already diminished at 0,01mM and lost total activity at 4mM, indicating sensitivity for this type of metal. β-D-N-acetilglucosaminidase-ferromagnetic Dacron showed degradative capacity on heparan sulfate, the enzyme still demonstrated degradative capacity on heparan sulphate, suggesting a possible application to produce fractions of this glycosaminoglycan

A β-D-N-acetilglucosaminidase, extraída e parcialmente isolada do crustáceo Artemia franciscana através de precipitação com sulfato de amônio e cromatografia em gel filtração Bio Gel A 1.5m foi imobilizada em Dacron ferromagnético rendendo um derivado insolúvel ativo contendo 5,0 unid/mg de proteína e retendo 10,35% da atividade da enzima solúvel. A β-D-N-acetilglucosaminidase-Dacron ferromagnético foi facilmente removida do meio reacional com o auxílio de um campo magnético e pôde ser reutilizada por dez vezes seguidas sem perda de atividade. O Dacron ferromagnético foi melhor ativado a pH 5,0 As partículas visualizadas no microscópio eletrônico de varredura (MEV) apresentaram diferentes tamanhos, variando entre 721nm e 100m. O infra vermelho confirmou a imobilização ao suporte, quando exibiu os picos de aminas primárias a 1640 e 1560 cm-1 . A enzima imobilizada apresentou Km aparente de 2,32 0,48 mM e atividade ótima a temperatura de 50C. Ambos apresentaram praticamente a mesma estabilidade térmica da enzima solúvel e maior atividade enzimática no pH 5,5. A β-D-N-acetilglucosaminidase-Dacron ferromagnético apresentou-se sensível a alguns íons como a prata (AgNO3), demonstrando perda de atividade. A atividade β-D-N-acetilglucosaminidasica para cloreto de mercúrio (HgCl2), que é uma das substâncias mais tóxicas encontradas na natureza, apresentou-se diminuída já a 0,01mM e…

Advisors/Committee Members: Hugo Alexandre de Oliveira Rocha, Wogelsanger Oliveira Pereira, Carlos Eduardo Bezerra de Moura.

Subjects/Keywords: β; -D-N-acetilglucosaminidase; Imobilização; Enzima; Artemia franciscana; Biotecnologia; BIOQUIMICA; β; -D-N-acetylglucosaminidase; Immobilization; Enzyme; Artemia franciscana; Biotechnology

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Santos, P. d. C. (2008). Atividade β-D-N-Acetilglucosaminidásica de enzimas imobilizadas extraídas da Artemia franciscana e possíveis aplicações biotecnológicas. (Thesis). Universidade Federal do Rio Grande do Norte. Retrieved from http://bdtd.bczm.ufrn.br/tedesimplificado//tde_busca/arquivo.php?codArquivo=2284

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Santos, Pablo de Castro. “Atividade β-D-N-Acetilglucosaminidásica de enzimas imobilizadas extraídas da Artemia franciscana e possíveis aplicações biotecnológicas.” 2008. Thesis, Universidade Federal do Rio Grande do Norte. Accessed January 20, 2021. http://bdtd.bczm.ufrn.br/tedesimplificado//tde_busca/arquivo.php?codArquivo=2284.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Santos, Pablo de Castro. “Atividade β-D-N-Acetilglucosaminidásica de enzimas imobilizadas extraídas da Artemia franciscana e possíveis aplicações biotecnológicas.” 2008. Web. 20 Jan 2021.

Vancouver:

Santos PdC. Atividade β-D-N-Acetilglucosaminidásica de enzimas imobilizadas extraídas da Artemia franciscana e possíveis aplicações biotecnológicas. [Internet] [Thesis]. Universidade Federal do Rio Grande do Norte; 2008. [cited 2021 Jan 20]. Available from: http://bdtd.bczm.ufrn.br/tedesimplificado//tde_busca/arquivo.php?codArquivo=2284.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Santos PdC. Atividade β-D-N-Acetilglucosaminidásica de enzimas imobilizadas extraídas da Artemia franciscana e possíveis aplicações biotecnológicas. [Thesis]. Universidade Federal do Rio Grande do Norte; 2008. Available from: http://bdtd.bczm.ufrn.br/tedesimplificado//tde_busca/arquivo.php?codArquivo=2284

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universidade do Rio Grande do Norte

7. Santos, Pablo de Castro. Atividade β-D-N-Acetilglucosaminidásica de enzimas imobilizadas extraídas da Artemia franciscana e possíveis aplicações biotecnológicas .

Degree: 2008, Universidade do Rio Grande do Norte

URL: http://repositorio.ufrn.br/handle/123456789/12538

► A β-D-N-acetilglucosaminidase extracted and partially isolated from crustacean Artemia franciscana by ammonium sulfate precipitation and filtration gel chromatography Bio Gel A 1.5m. the enzyme was… (more)

Subjects/Keywords: β; -D-N-acetilglucosaminidase; Imobilização; Enzima; Artemia franciscana; Biotecnologia; β; -D-N-acetylglucosaminidase; Immobilization; Enzyme; Artemia franciscana; Biotechnology

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Santos, P. d. C. (2008). Atividade β-D-N-Acetilglucosaminidásica de enzimas imobilizadas extraídas da Artemia franciscana e possíveis aplicações biotecnológicas . (Thesis). Universidade do Rio Grande do Norte. Retrieved from http://repositorio.ufrn.br/handle/123456789/12538

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Santos, Pablo de Castro. “Atividade β-D-N-Acetilglucosaminidásica de enzimas imobilizadas extraídas da Artemia franciscana e possíveis aplicações biotecnológicas .” 2008. Thesis, Universidade do Rio Grande do Norte. Accessed January 20, 2021. http://repositorio.ufrn.br/handle/123456789/12538.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Santos, Pablo de Castro. “Atividade β-D-N-Acetilglucosaminidásica de enzimas imobilizadas extraídas da Artemia franciscana e possíveis aplicações biotecnológicas .” 2008. Web. 20 Jan 2021.

Vancouver:

Santos PdC. Atividade β-D-N-Acetilglucosaminidásica de enzimas imobilizadas extraídas da Artemia franciscana e possíveis aplicações biotecnológicas . [Internet] [Thesis]. Universidade do Rio Grande do Norte; 2008. [cited 2021 Jan 20]. Available from: http://repositorio.ufrn.br/handle/123456789/12538.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Santos PdC. Atividade β-D-N-Acetilglucosaminidásica de enzimas imobilizadas extraídas da Artemia franciscana e possíveis aplicações biotecnológicas . [Thesis]. Universidade do Rio Grande do Norte; 2008. Available from: http://repositorio.ufrn.br/handle/123456789/12538

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Vilnius University

8. Dodonova, Jelena. Pirolo[2,3-d]pirimidino oligoarilenų sintezė ir fotofizikinės savybės.

Degree: PhD, Chemistry, 2012, Vilnius University

URL: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2012~D_20120917_092617-49864 ;

►

Šio darbo tikslas buvo susintetinti pirolo[2,3-d]pirimidino oligoarilenus ir ištirti jų fotofizikines savybes. Rezultate, ištirta 2,4-dichlorpirolo[2,3-d]pirimidino Suzuki reakcija su arilborono rūgštimis bei susintetinti nauji 4-aril- ir… (more)

▼

Šio darbo tikslas buvo susintetinti pirolo[2,3-d]pirimidino oligoarilenus ir ištirti jų fotofizikines savybes. Rezultate, ištirta 2,4-dichlorpirolo[2,3-d]pirimidino Suzuki reakcija su arilborono rūgštimis bei susintetinti nauji 4-aril- ir 2,4-diarilpirolo[2,3-d]pirimidinai. Pasiūlyta katalitinė sistema bei surastos reakcijos sąlygos, leidžiančios regioselektyviai atlikti Suzuki kryžminio jungimo reakciją 2,4-dichlorpirolo[2,3-d]pirimidine. Ištirta variu(I) katalizuojama N-arilinimo reakcija tarp 2,4-diarilpirolo[2,3-d]pirimidinų ir įvairių arilhalogenidų, dihalokarbazolų ir dihalofluorenų bei susintetinti 2,4,7-triarilpirolo[2,3-d]pirimidinai, bis(pirolo[2,3-d]pirimidin-7-il)karbazolai ir atitinkami fluorenai. Sukurtas būdas, leidžiantis sintetinti pirolo[2,3-d]pirimidinus su įvairiais pakaitais 2-, 4- ir 7-oje heterociklo padėtyse. Pirmą kartą nustatyta, kad pirolo[2,3-d]pirimidino oligoarilenai pasižymi mėlyna-UV fluorescencija tirpale ir kietame būvyje. Ištirta arilgrupių struktūros, padėties pirolo[2,3-d]pirimidino žiede bei pi-konjuguotos sistemos dydžio įtaka junginių fotoliuminescencinėms savybėms. Nustatyta, kad kai kurie pirolo[2,3-d]pirimidino oligoarilenai pasižymi teigiamu solvatofluorochrominiu efektu, sudaro nanoagregatus tetrahidrofurano/vandens mišinyje. Nustatyta, kad molekulių agregacija indukuoja emisijos padidėjimą. Parodyta, kad pirolo[2,3-d]pirimidino oligomerai su išplėsta pi-konjuguota sistema efektyviau fluorescuoja kietame būvyje nei tirpale.

The main goal of the present work was to synthesize pyrrolo[2,3-d]pyrimidine core based oligoarylenes and to evaluate their photophysical properties. As a result, the Suzuki reaction of 2,4-dichloropyrrolo[2,3-d]pyrimidine with arylboronic acids was studied and novel 4-aryl- and 2,4-diarylpyrrolo[2,3-d]pyrimidines were synthesized. The reaction conditions including an effective catalyst system for the Suzuki cross-coupling reaction were proposed to achieve site-selectivity of the reaction studied. A general approach for the preparation of 2,4,7-triarylpyrrolo[2,3-d]pyrimidines, bis(pyrrolo[2,3-d]pyrimidin-7-yl)carbazoles and -fluorenes were developed by copper-catalyzed N-arylation reaction of 2,4-diarylpyrrolo[2,3-d]pyrimidines with aryl halogenides, dihalocarbazoles or dihalofluorenes. Synthetic strategies leading to pyrrolo[2,3-d]pyrimidines with different aryl moieties in positions 2, 4 and 7 of the heterocycle were studied and an efficient method for their synthesis was developed. The synthesized pyrrolo[2,3-d]pyrimidine-core based oligoarylenes were found to exhibit blue-UV fluorescence in solution and in solid state. Influence of structure of aryl groups, their position in the pyrrolo[2,3-d]pyrimidine nucleous and extent of pi-conjugated aromatic system on the photoluminescent characteristics were evaluated. Some pyrrolo[2,3-d]pyrimidine derivatives were found to exhibit positive solvatofluorochromism and to form nanoaggregates in THF/water mixtures with aggregation... [to full text]

Advisors/Committee Members: Vainilavičius, Povilas (Doctoral dissertation committee chair), Butkus, Eugenijus (Doctoral dissertation committee member), Malinauskas, Albertas (Doctoral dissertation committee member), Mickevičius, Vytautas (Doctoral dissertation committee member), Undzėnas, Algimantas (Doctoral dissertation committee member), Burbulienė, Milda Malvina (Doctoral dissertation opponent), Getautis, Vytautas (Doctoral dissertation opponent), Tumkevičius, Sigitas (Doctoral dissertation supervisor).

Subjects/Keywords: Pirolo[2; 3-d]pirimidinas; Fluorescencija; Suzuki reakcija; N-arilinimas; Pyrrolo[2; 3-d]pyrimidine; Fluorescence; Suzuki reaction; N-arylation

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Dodonova, J. (2012). Pirolo[2,3-d]pirimidino oligoarilenų sintezė ir fotofizikinės savybės. (Doctoral Dissertation). Vilnius University. Retrieved from http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2012~D_20120917_092617-49864 ;

Chicago Manual of Style (16^th Edition):

Dodonova, Jelena. “Pirolo[2,3-d]pirimidino oligoarilenų sintezė ir fotofizikinės savybės.” 2012. Doctoral Dissertation, Vilnius University. Accessed January 20, 2021. http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2012~D_20120917_092617-49864 ;.

MLA Handbook (7^th Edition):

Dodonova, Jelena. “Pirolo[2,3-d]pirimidino oligoarilenų sintezė ir fotofizikinės savybės.” 2012. Web. 20 Jan 2021.

Vancouver:

Dodonova J. Pirolo[2,3-d]pirimidino oligoarilenų sintezė ir fotofizikinės savybės. [Internet] [Doctoral dissertation]. Vilnius University; 2012. [cited 2021 Jan 20]. Available from: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2012~D_20120917_092617-49864 ;.

Council of Science Editors:

Dodonova J. Pirolo[2,3-d]pirimidino oligoarilenų sintezė ir fotofizikinės savybės. [Doctoral Dissertation]. Vilnius University; 2012. Available from: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2012~D_20120917_092617-49864 ;

Vilnius University

9. Dodonova, Jelena. Synthesis and photophysical properties of pyrrolo[2,3-d]pyrimidine-core based oligoarylenes.

Degree: Dissertation, Chemistry, 2012, Vilnius University

URL: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2012~D_20120917_092627-68184 ;

►

The main goal of the present work was to synthesize pyrrolo[2,3-d]pyrimidine core based oligoarylenes and to evaluate their photophysical properties. As a result, the Suzuki… (more)

▼

The main goal of the present work was to synthesize pyrrolo[2,3-d]pyrimidine core based oligoarylenes and to evaluate their photophysical properties. As a result, the Suzuki reaction of 2,4-dichloropyrrolo[2,3-d]pyrimidine with arylboronic acids was studied and novel 4-aryl- and 2,4-diarylpyrrolo[2,3-d]pyrimidines were synthesized. The reaction conditions including an effective catalyst system for the Suzuki cross-coupling reaction were proposed to achieve site-selectivity of the reaction studied. A general approach for the preparation of 2,4,7-triarylpyrrolo[2,3-d]pyrimidines, bis(pyrrolo[2,3-d]pyrimidin-7-yl)carbazoles and -fluorenes were developed by copper-catalyzed N-arylation reaction of 2,4-diarylpyrrolo[2,3-d]pyrimidines with aryl halogenides, dihalocarbazoles or dihalofluorenes. Synthetic strategies leading to pyrrolo[2,3-d]pyrimidines with different aryl moieties in positions 2, 4 and 7 of the heterocycle were studied and an efficient method for their synthesis was developed. The synthesized pyrrolo[2,3-d]pyrimidine-core based oligoarylenes were found to exhibit blue-UV fluorescence in solution and in solid state. Influence of structure of aryl groups, their position in the pyrrolo[2,3-d]pyrimidine nucleous and extent of pi-conjugated aromatic system on the photoluminescent characteristics were evaluated. Some pyrrolo[2,3-d]pyrimidine derivatives were found to exhibit positive solvatofluorochromism and to form nanoaggregates in THF/water mixtures with aggregation... [to full text]

Šio darbo tikslas buvo susintetinti pirolo[2,3-d]pirimidino oligoarilenus ir ištirti jų fotofizikines savybes. Rezultate, ištirta 2,4-dichlorpirolo[2,3-d]pirimidino Suzuki reakcija su arilborono rūgštimis bei susintetinti nauji 4-aril- ir 2,4-diarilpirolo[2,3-d]pirimidinai. Pasiūlyta katalitinė sistema bei surastos reakcijos sąlygos, leidžiančios regioselektyviai atlikti Suzuki kryžminio jungimo reakciją 2,4-dichlorpirolo[2,3-d]pirimidine. Ištirta variu(I) katalizuojama N-arilinimo reakcija tarp 2,4-diarilpirolo[2,3-d]pirimidinų ir įvairių arilhalogenidų, dihalokarbazolų ir dihalofluorenų bei susintetinti 2,4,7-triarilpirolo[2,3-d]pirimidinai, bis(pirolo[2,3-d]pirimidin-7-il)karbazolai ir atitinkami fluorenai. Sukurtas būdas, leidžiantis sintetinti pirolo[2,3-d]pirimidinus su įvairiais pakaitais 2-, 4- ir 7-oje heterociklo padėtyse. Pirmą kartą nustatyta, kad pirolo[2,3-d]pirimidino oligoarilenai pasižymi mėlyna-UV fluorescencija tirpale ir kietame būvyje. Ištirta arilgrupių struktūros, padėties pirolo[2,3-d]pirimidino žiede bei pi-konjuguotos sistemos dydžio įtaka junginių fotoliuminescencinėms savybėms. Nustatyta, kad kai kurie pirolo[2,3-d]pirimidino oligoarilenai pasižymi teigiamu solvatofluorochrominiu efektu, sudaro nanoagregatus tetrahidrofurano/vandens mišinyje. Nustatyta, kad molekulių agregacija indukuoja emisijos padidėjimą. Parodyta, kad pirolo[2,3-d]pirimidino oligomerai su išplėsta pi-konjuguota sistema efektyviau fluorescuoja kietame būvyje nei tirpale.

Advisors/Committee Members: Vainilavičius, Povilas (Doctoral dissertation committee chair), Butkus, Eugenijus (Doctoral dissertation committee member), Malinauskas, Albertas (Doctoral dissertation committee member), Mickevičius, Vytautas (Doctoral dissertation committee member), Undzėnas, Algimantas (Doctoral dissertation committee member), Burbulienė, Milda Malvina (Doctoral dissertation opponent), Getautis, Vytautas (Doctoral dissertation opponent), Tumkevičius, Sigitas (Doctoral dissertation supervisor).

Subjects/Keywords: Pyrrolo[2; 3-d]pyrimidine; Fluorescence; Suzuki reaction; N-arylation; Pirolo[2; 3-d]pirimidinas; Fluorescencija; Suzuki reakcija; N-arilinimas

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Dodonova, J. (2012). Synthesis and photophysical properties of pyrrolo[2,3-d]pyrimidine-core based oligoarylenes. (Doctoral Dissertation). Vilnius University. Retrieved from http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2012~D_20120917_092627-68184 ;

Chicago Manual of Style (16^th Edition):

Dodonova, Jelena. “Synthesis and photophysical properties of pyrrolo[2,3-d]pyrimidine-core based oligoarylenes.” 2012. Doctoral Dissertation, Vilnius University. Accessed January 20, 2021. http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2012~D_20120917_092627-68184 ;.

MLA Handbook (7^th Edition):

Dodonova, Jelena. “Synthesis and photophysical properties of pyrrolo[2,3-d]pyrimidine-core based oligoarylenes.” 2012. Web. 20 Jan 2021.

Vancouver:

Dodonova J. Synthesis and photophysical properties of pyrrolo[2,3-d]pyrimidine-core based oligoarylenes. [Internet] [Doctoral dissertation]. Vilnius University; 2012. [cited 2021 Jan 20]. Available from: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2012~D_20120917_092627-68184 ;.

Council of Science Editors:

Dodonova J. Synthesis and photophysical properties of pyrrolo[2,3-d]pyrimidine-core based oligoarylenes. [Doctoral Dissertation]. Vilnius University; 2012. Available from: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2012~D_20120917_092627-68184 ;

10. Aline Aparecida Becaro. Imobilização e estabilização de D-Hidantoinase para a produção de N-Carbamoil-D-Fenilglicina.

Degree: 2008, Universidade Federal de São Carlos

URL: http://www.bdtd.ufscar.br/htdocs/tedeSimplificado//tde_busca/arquivo.php?codArquivo=2869

►

A imobilização e estabilização de enzimas aumentam muito o potencial de uso industrial desses catalisadores. D-hidantoinases (dihidropirimidina amidrohidrolase EC 3.5.2.2) são enzimas que catalisam a… (more)

▼

A imobilização e estabilização de enzimas aumentam muito o potencial de uso industrial desses catalisadores. D-hidantoinases (dihidropirimidina amidrohidrolase EC 3.5.2.2) são enzimas que catalisam a hidrólise de hidantoínas, com abertura do anel, para o correspondente N-carbamoil-D-aminoácido e são usadas na produção de Daminoácidos, incluindo D-fenilglicina e D-p-hidroxifenilglicina. Este trabalho relata os estudos desenvolvidos para a imobilização e estabilização de D-hidantoinase de Vigna angularis (3.5.2.2.). Foram abordadas diferentes estratégias de imobilização multipontual em suportes orgânicos como quitosana e agarose. Diferentes protocolos de imobilização foram empregados, sendo adição de íons durante a redução com NaBH4 importante para proteção do centro catalítico da enzima. Os derivados ativos e estabilizados foram empregados na reação de hidrólise da fenilhidantoína. O estudo de temperatura e pH de máxima atividade da enzima foi 60C e pH 10,0. As subunidades da enzima apresentam peso molecular, com valor próximo a 50kDa. A enzima imobilizada em glioxil-agarose na presença dos íons Zn2+ durante a etapa de redução, com tempo de imobilização de 24 h foi o derivado mais estável sendo 89 vezes mais estável que a enzima solúvel. A análise de aminoácidos mostrou que aproximadamente 50% dos resíduos de lisina presentes na enzima foram covalentemente ligados no derivado de glioxil-agarose. A enzima imobilizada em quitosana-alginato-epoxilado foi 20 vezes mais estável que a enzima solúvel. Todos os procedimentos de imobilização testados levaram a 100% de rendimento de imobilização. Enzima solúvel e os melhores derivados obtidos por imobilização em glioxil e quitosana foram usados na catálise da hidrólise de fenilhidantoína, produzindo 99% de N-Carbamoil-D-fenilglicina nos tempos de 3, 9 e 15 h, respectivamente.

Immobilization and stabilization of enzymes increases their potential for use in industrial scale. D-hydantoinases (dihidropirimidina amidrohidrolase EC 3.5.2.2) catalyze the hydrolysis of D-hydantoins, generating the corresponding Ncarbamoil- D-amino acid and are used in the production of D-amino acids, including Dphenylglycine and D-p-hydroxyphenylglycine.This work reports studies for immobilization and stabilization of D-hydantoinase from Vigna angularis (E.C. 3.5.2.2.). Different strategies of multipoint covalent attachment in organic supports as chitosan and agarose were used. Different protocols of immobilization were employed, being the adittion of ions during the reduction step with the NaBH4 important to protect enzyme catalytic site. The active and stabilized derivatives were used to catalyze the hydrolysis of D-phenylhydantoin. The temperature and pH enzyme profiles showed maximum enzyme activity at 60C and pH 10,0. The subunits of the enzyme present molecular mass aroundt 50kDa. The enzyme immobilized in glyoxyl-agarose in the presence of Zn2+ ions during the reduction step, with immobilization time of 24h, was the best derivative, being 89-fold more stable than the soluble enzyme. The…

Advisors/Committee Members: Raquel de Lima Camargo Giordano.

Subjects/Keywords: Enzimas; Imobilização multipontual; Biotecnologia; D-Hidantoinase; Glioxil-agarose; Epóxiquitosana-alginato; N-Carbamoil-D-fenilglicina.; Exatas e da Terra; Multipoint immobilization; D-hydantoinase; Glyoxyl-agarose; Epoxy-chitosanalginate; N-carbamoyl-D-phenylglycine

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Becaro, A. A. (2008). Imobilização e estabilização de D-Hidantoinase para a produção de N-Carbamoil-D-Fenilglicina. (Thesis). Universidade Federal de São Carlos. Retrieved from http://www.bdtd.ufscar.br/htdocs/tedeSimplificado//tde_busca/arquivo.php?codArquivo=2869

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Becaro, Aline Aparecida. “Imobilização e estabilização de D-Hidantoinase para a produção de N-Carbamoil-D-Fenilglicina.” 2008. Thesis, Universidade Federal de São Carlos. Accessed January 20, 2021. http://www.bdtd.ufscar.br/htdocs/tedeSimplificado//tde_busca/arquivo.php?codArquivo=2869.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Becaro, Aline Aparecida. “Imobilização e estabilização de D-Hidantoinase para a produção de N-Carbamoil-D-Fenilglicina.” 2008. Web. 20 Jan 2021.

Vancouver:

Becaro AA. Imobilização e estabilização de D-Hidantoinase para a produção de N-Carbamoil-D-Fenilglicina. [Internet] [Thesis]. Universidade Federal de São Carlos; 2008. [cited 2021 Jan 20]. Available from: http://www.bdtd.ufscar.br/htdocs/tedeSimplificado//tde_busca/arquivo.php?codArquivo=2869.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Becaro AA. Imobilização e estabilização de D-Hidantoinase para a produção de N-Carbamoil-D-Fenilglicina. [Thesis]. Universidade Federal de São Carlos; 2008. Available from: http://www.bdtd.ufscar.br/htdocs/tedeSimplificado//tde_busca/arquivo.php?codArquivo=2869

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

11. Sparta', Roberta. Indirect 2H(d,p)3H and 2H(d,n)3He fusion reactions measurement at energies relevant for Big Bang Nucleosynthesis.

Degree: 2013, Università degli Studi di Catania

URL: http://hdl.handle.net/10761/1429

► The work presented in this thesis is focused on the experimental study of the two deuterium burning channels 2H(d,p)3H and 2H(d,n)3He in the Big Bang… (more)

▼ The work presented in this thesis is focused on the experimental study of the two deuterium burning channels 2H(d,p)3H and 2H(d,n)3He in the Big Bang Nucleosynthesis (BBN) astrophysical scenario. In the beginning is presented this phase of the early universe and why the BBN model is still fine tuned with new results coming from observations and laboratory measurements. This model (if BBN is considered standard) can be adjusted such to have only a free parameter, the baryon to photon ratio of the universe eta at a certain time. Also the WMAP satellite results have been of great help to fix eta (and then all the others BBN numbers), but still persist some discrepancies, as for the lithium primordial abundances, between what is theoretically predicted and what is observed. The deuterium (and the reactions in which is involved) plays a key role in the evaluation of eta, thus for all BBN, so that is called the best baryometer. Then is explained that the need of new cross sections (and reaction rates) measurements for astrophysics can not be satisfied. This is because of the problems given by their measurements in the laboratory, as the presence of Coulomb barrier (that makes cross sections exponentially decrease in the energy range of interest) and the electron screening effect. For all these reasons the present measurements have been performed through the Trojan Horse Method (THM), an indirect method that allow to have a bare-nucleus cross section of the two-body reaction of astrophysical interest that is free of the Coulomb suppression. This is accomplished via the selection of the quasi-free mechanism in an appropriate three-body reaction, whose center-of-mass energy is greater than the Coulomb barrier. Two experimental runs have been carried out at the Nuclear Physics Institute of the Academy of Science of Czech Republic, in Rez (Prague). In the first one, with a 17 MeV 3He beam (in which only 2H(d,p)3H has been measured) the presence of quasi-free mechanism events has been ascertained. The result obtained is fair but not good enough for the error reduction needed for astrophysics. Instead, to optimize the result in the region relecant for astrophysics, a the second run (where the 3He beam energy was 18 MeV) has been performed. In particular for the first time the technique of measuring one of the two-body reactions participant ejectile and the spectator particle, in this case a proton, instead of both the ejectiles. This has also allowed the measure of the 2H(d,n)3He reaction without the complexity of the neutron detection, so with a very good precision. All the off-line analysis done until the S-factor extraction is detailed explained, including the MPWBA analysis by Dr. S. Typel. Also the screening potential has been evaluated, obtaining a value of 13.2±1.8 eV for 2H(d,p)3H and 11.7±1.6 eV for 2H(d,n)3He, very close to the adiabatic limit, as expected. A pole invariance test has been provided comparing present results with previous TH data, where the 6Li was used as TH nucleus. Reaction rates from present TH…

Subjects/Keywords: Area 02 - Scienze fisiche; nuclear astrophysics, d+d, d(d,p)t, d(d,n)3he, BBN, Big Bang Nucleosynthesis, reaction rate, eta, baryon-to-photon ratio, THM, Trojan Horse Method, 2H(d,p)3H, 2H(d,n)3He

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Sparta', R. (2013). Indirect 2H(d,p)3H and 2H(d,n)3He fusion reactions measurement at energies relevant for Big Bang Nucleosynthesis. (Thesis). Università degli Studi di Catania. Retrieved from http://hdl.handle.net/10761/1429

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Sparta', Roberta. “Indirect 2H(d,p)3H and 2H(d,n)3He fusion reactions measurement at energies relevant for Big Bang Nucleosynthesis.” 2013. Thesis, Università degli Studi di Catania. Accessed January 20, 2021. http://hdl.handle.net/10761/1429.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Sparta', Roberta. “Indirect 2H(d,p)3H and 2H(d,n)3He fusion reactions measurement at energies relevant for Big Bang Nucleosynthesis.” 2013. Web. 20 Jan 2021.

Vancouver:

Sparta' R. Indirect 2H(d,p)3H and 2H(d,n)3He fusion reactions measurement at energies relevant for Big Bang Nucleosynthesis. [Internet] [Thesis]. Università degli Studi di Catania; 2013. [cited 2021 Jan 20]. Available from: http://hdl.handle.net/10761/1429.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Sparta' R. Indirect 2H(d,p)3H and 2H(d,n)3He fusion reactions measurement at energies relevant for Big Bang Nucleosynthesis. [Thesis]. Università degli Studi di Catania; 2013. Available from: http://hdl.handle.net/10761/1429

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universidade do Rio Grande do Sul

12. Zenki, Kamila Cagliari. Efeito neuroprotetor do antagonismo do receptor N-metil-D-aspartato pela memantina sobre a neurogeneração induzida pelo status epilepticus em ratos jovens.

Degree: 2015, Universidade do Rio Grande do Sul

URL: http://hdl.handle.net/10183/115047

►

O Status epilepticus induzido por LiCl-pilocarpina causa uma massiva neurodegeneração em diversas regiões cerebrais, e a maioria dos fármacos antiepilépticos clássicos não são suficientemente eficazes… (more)

▼

O Status epilepticus induzido por LiCl-pilocarpina causa uma massiva neurodegeneração em diversas regiões cerebrais, e a maioria dos fármacos antiepilépticos clássicos não são suficientemente eficazes para proteger os neurônios da morte. Antagonistas do receptor N-metil-D-aspartato apresentam ação anticonvulsiva e são atualmente capazes de proporcionar neuroprotecção contra a morte neuronal induzida pelo SE. No entanto, estes compostos demonstraram inúmeros efeitos colaterais. Apesar disso, a memantina, um antagonista NMDA de baixa afinidade, é clinicamente bem tolerada e não induz tantos efeitos indesejados. Portanto, o objetivo do presente estudo foi investigar o efeito neuroprotetor da memantina contra a degeneração neuronal induzida pelo status epilepticus induzido por LiCl-pilocarpina nos períodos iniciais da vida. Filhotes de ratos Wistar receberam memantina (20 mg / kg ip) em diferentes regimes de tratamento. A neurodegeneração foi quantificada por fluoro jade C. Em CA1 a neurodegeneração diminuiu significativamente quando os animais receberam memantina nos regimes de pós-tratamento realizados às 0 e 0,25 horas. Além disso, o pós-tratamento foi capaz de proteger contra a neurodegeneração em uma região da amígdala. O pré-tratamento com memantina mostrou uma redução da morte celular no tálamo. Nossos resultados demonstram o efeito neuroprotetor da memantina na morte neuronal induzida pelo SE no início da vida. Este efeito é dependente do tempo de tratamento e da região cerebral.

Status epilepticus induced by LiCl-pilocarpine is accompanied by neurodegeneration and the classical antiepileptic drugs are not effective in protect neurons from death. Typical N-methyl-D-aspartate receptor antagonists exhibit anticonvulsant action and are currently able to provide neuroprotection against SE-induced neuronal death. However, these compounds have demonstrated undesirable side effects. Despite this, memantine, a low-affinity NMDA antagonist, is clinically well tolerate and does not induce side effects. Therefore, the aim of the present study was to investigate the neuroprotective effect of the memantine against neuronal degeneration induced by early life LiCl-Pilocarpine-induced status epilepticus. Wistar pup rats received memantine (20 mg/kg i.p.) at different treatment regimens before and after SE induction. Neurodegeneration was quantified by fluoro jade C staining. In CA1 subfield neurodegeneration was significantly decreased when animals received memantine at 0h and 0.25h post-treatment regimens. Additionally, post-treatment was able to protect against neurodegeneration in amygdala region. Memantine pre-treatment showed a reduction of cell death in thalamus. Our results demonstrated the neuroprotective effect of memantine on neuronal loss induced by SE early in life. This effect was time- and region-dependent.

Advisors/Committee Members: Oliveira, Diogo Losch de.

Subjects/Keywords: Degeneracao neural; Neuroproteção; Epilepsia; Memantina; N-Metil-D-Aspartato

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Zenki, K. C. (2015). Efeito neuroprotetor do antagonismo do receptor N-metil-D-aspartato pela memantina sobre a neurogeneração induzida pelo status epilepticus em ratos jovens. (Thesis). Universidade do Rio Grande do Sul. Retrieved from http://hdl.handle.net/10183/115047

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Zenki, Kamila Cagliari. “Efeito neuroprotetor do antagonismo do receptor N-metil-D-aspartato pela memantina sobre a neurogeneração induzida pelo status epilepticus em ratos jovens.” 2015. Thesis, Universidade do Rio Grande do Sul. Accessed January 20, 2021. http://hdl.handle.net/10183/115047.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Zenki, Kamila Cagliari. “Efeito neuroprotetor do antagonismo do receptor N-metil-D-aspartato pela memantina sobre a neurogeneração induzida pelo status epilepticus em ratos jovens.” 2015. Web. 20 Jan 2021.

Vancouver:

Zenki KC. Efeito neuroprotetor do antagonismo do receptor N-metil-D-aspartato pela memantina sobre a neurogeneração induzida pelo status epilepticus em ratos jovens. [Internet] [Thesis]. Universidade do Rio Grande do Sul; 2015. [cited 2021 Jan 20]. Available from: http://hdl.handle.net/10183/115047.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Zenki KC. Efeito neuroprotetor do antagonismo do receptor N-metil-D-aspartato pela memantina sobre a neurogeneração induzida pelo status epilepticus em ratos jovens. [Thesis]. Universidade do Rio Grande do Sul; 2015. Available from: http://hdl.handle.net/10183/115047

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

13. Chopra, Divyan A. Identification of novel gating mechanisms underlying pharmacological potentiation of NMDA receptors.

Degree: M.S. in Pharmaceutical Sciences, Pharmacology (graduate program), 2015, Creighton University

URL: http://hdl.handle.net/10504/71410

► Excitatory neurotransmission mediated by N-methyl-D-aspartate receptors (NMDARs) is known to play an important role in synaptic plasticity, learning and memory. Moreover, NMDAR dysfunction may contribute… (more)

▼ Excitatory neurotransmission mediated by N-methyl-D-aspartate receptors (NMDARs) is known to play an important role in synaptic plasticity, learning and memory. Moreover, NMDAR dysfunction may contribute to a variety of neuropsychiatric and neurological disorders including schizophrenia, epilepsy, stroke and trauma. Pregnenolone sulfate (PS) is one of the most commonly occurring neurosteroids in the central nervous system and influences function of several receptors. PS modulates NMDARs and has been shown to have both positive and negative modulatory effects on NMDAR currents generally in a subtype-selective manner. We assessed the gating mechanism of PS modulation of GluN1/GluN2A receptors transiently expressed in HEK 293 cells using whole-cell and single-channel electrophysiology. Only a modest effect on the whole-cell responses was observed by PS in dialyzed (non-perforated) whole-cell recordings. Interestingly, in perforated conditions, PS was found to increase the whole-cell currents in the absence of nominal extracellular Ca2+ whereas PS produced an inhibition of the current responses in the presence of 0.5 mM extracellular Ca2+. The Ca2+-binding DRPEER motif and GluN1 exon-5 were found to be critical for the Ca2+-dependent bidirectional effect of PS. Single-channel cell-attached analysis demonstrated that PS primarily affected the mean open time to produce its effects, with positive modulation mediated by an increase in duration of open time constants while negative modulation mediated by a reduction in the time spent in a long-lived open state of the receptor. Further kinetic modeling of the single-channel data suggested that the positive and negative modulatory effects are mediated by different gating steps which may represent GluN2 and GluN1 subunit-selective conformational changes respectively. Our studies provide a unique mechanism of modulation of NMDARs by an endogenous neurosteroid which has implications for identifying state-dependent molecules. UBP (University of Bristol Pharmaceuticals) series compounds act at allosteric binding sites on the NMDARs and have been able to achieve subtype-selectivity. We found that UBP684 significantly increased the whole-cell current and mean open time and reduced the mean shut time for GluN1/GluN2A receptors. Mutagenesis studies suggest that UBP684 can stabilize the closed cleft of the LBD and drive the receptor into the more stable open states. Advisors/Committee Members: Dravid, Shashank M. (advisor), Chopra, Divyan A. (cuauthor).

Subjects/Keywords: Pregnenolone – metabolism; Receptors, N-Methyl-D-Aspartate – physiology

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Chopra, D. A. (2015). Identification of novel gating mechanisms underlying pharmacological potentiation of NMDA receptors. (Masters Thesis). Creighton University. Retrieved from http://hdl.handle.net/10504/71410

Chicago Manual of Style (16^th Edition):

Chopra, Divyan A. “Identification of novel gating mechanisms underlying pharmacological potentiation of NMDA receptors.” 2015. Masters Thesis, Creighton University. Accessed January 20, 2021. http://hdl.handle.net/10504/71410.

MLA Handbook (7^th Edition):

Chopra, Divyan A. “Identification of novel gating mechanisms underlying pharmacological potentiation of NMDA receptors.” 2015. Web. 20 Jan 2021.

Vancouver:

Chopra DA. Identification of novel gating mechanisms underlying pharmacological potentiation of NMDA receptors. [Internet] [Masters thesis]. Creighton University; 2015. [cited 2021 Jan 20]. Available from: http://hdl.handle.net/10504/71410.

Council of Science Editors:

Chopra DA. Identification of novel gating mechanisms underlying pharmacological potentiation of NMDA receptors. [Masters Thesis]. Creighton University; 2015. Available from: http://hdl.handle.net/10504/71410

14. Ravikrishnan, Aparna. Role of GluN2C-containing NMDA Receptors in Cellular and Behavioral Deficits Associated with Corticothalamic Circuit Dysfunction in Schizophrenia.

Degree: M.S. in Pharmaceutical Sciences, Pharmaceutical Science (graduate program), 2015, Creighton University

URL: http://hdl.handle.net/10504/72899

► The NMDA receptor (NMDAR) hypofunction hypothesis in schizophrenia posits that reduced NMDAR function leads to behavioral abnormalities observed in schizophrenia. Lower expression of GluN2C subunit… (more)

Subjects/Keywords: Protein Subunits – physiology; Schizophrenia – pathology; Receptors, N-Methyl-D-Aspartate – agonist.

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Ravikrishnan, A. (2015). Role of GluN2C-containing NMDA Receptors in Cellular and Behavioral Deficits Associated with Corticothalamic Circuit Dysfunction in Schizophrenia. (Masters Thesis). Creighton University. Retrieved from http://hdl.handle.net/10504/72899

Chicago Manual of Style (16^th Edition):

Ravikrishnan, Aparna. “Role of GluN2C-containing NMDA Receptors in Cellular and Behavioral Deficits Associated with Corticothalamic Circuit Dysfunction in Schizophrenia.” 2015. Masters Thesis, Creighton University. Accessed January 20, 2021. http://hdl.handle.net/10504/72899.

MLA Handbook (7^th Edition):

Ravikrishnan, Aparna. “Role of GluN2C-containing NMDA Receptors in Cellular and Behavioral Deficits Associated with Corticothalamic Circuit Dysfunction in Schizophrenia.” 2015. Web. 20 Jan 2021.

Vancouver:

Ravikrishnan A. Role of GluN2C-containing NMDA Receptors in Cellular and Behavioral Deficits Associated with Corticothalamic Circuit Dysfunction in Schizophrenia. [Internet] [Masters thesis]. Creighton University; 2015. [cited 2021 Jan 20]. Available from: http://hdl.handle.net/10504/72899.

Council of Science Editors:

Ravikrishnan A. Role of GluN2C-containing NMDA Receptors in Cellular and Behavioral Deficits Associated with Corticothalamic Circuit Dysfunction in Schizophrenia. [Masters Thesis]. Creighton University; 2015. Available from: http://hdl.handle.net/10504/72899

University of Texas Southwestern Medical Center

15. Reese, Austin Lowell. Spontaneous Neurotransmission as a Driver of Calcium Signaling.

Degree: 2016, University of Texas Southwestern Medical Center

URL: http://hdl.handle.net/2152.5/6148

► Spontaneous neurotransmission is a stochastic mode of neurotransmitter release that is not coupled to action potential arrival at the presynapse. Recent evidence has shed light… (more)

Subjects/Keywords: Calcium; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Reese, A. L. (2016). Spontaneous Neurotransmission as a Driver of Calcium Signaling. (Thesis). University of Texas Southwestern Medical Center. Retrieved from http://hdl.handle.net/2152.5/6148

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Reese, Austin Lowell. “Spontaneous Neurotransmission as a Driver of Calcium Signaling.” 2016. Thesis, University of Texas Southwestern Medical Center. Accessed January 20, 2021. http://hdl.handle.net/2152.5/6148.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Reese, Austin Lowell. “Spontaneous Neurotransmission as a Driver of Calcium Signaling.” 2016. Web. 20 Jan 2021.

Vancouver:

Reese AL. Spontaneous Neurotransmission as a Driver of Calcium Signaling. [Internet] [Thesis]. University of Texas Southwestern Medical Center; 2016. [cited 2021 Jan 20]. Available from: http://hdl.handle.net/2152.5/6148.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Reese AL. Spontaneous Neurotransmission as a Driver of Calcium Signaling. [Thesis]. University of Texas Southwestern Medical Center; 2016. Available from: http://hdl.handle.net/2152.5/6148

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University College London (University of London)

16. Rutter, Anthony Richard. Biochemical and pharmacological characterisation of the interaction between NMDA receptors and the scaffolding protein PSD-95.

Degree: PhD, 2001, University College London (University of London)

URL: https://discovery.ucl.ac.uk/id/eprint/10097895/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.248043

► The N-methyl-D-aspartate (NMDA) subtype of excitatory, ionotropic L-glutamate neurotransmitter receptor is a cation-selective, ligand-gated ion channel composed of NRl and NR2 subunits. NMDA receptors are… (more)

▼ The N-methyl-D-aspartate (NMDA) subtype of excitatory, ionotropic L-glutamate neurotransmitter receptor is a cation-selective, ligand-gated ion channel composed of NRl and NR2 subunits. NMDA receptors are localised on the dendritic spines of neurons where they are tightly associated with proteins of the post-synaptic density such as the scaffolding protein, post-synaptic density 95 (PSD-95). Many studies have characterised the pharmacological properties of NMDA receptors expressed in non-neuronal cell lines which lack the proteins of the post-synaptic density. The aim of this thesis was to investigate the effect of PSD-95 on the biochemical and pharmacological properties of NMDA receptors following their co-expression in mammalian cells. Various homomeric and heteromeric combinations of NR1-1 a, NR1-2a, NR1-4b, NR2A and NR2B subunits were expressed ± PSD-95 in human embryonic kidney 293 cells and analysed by quantitative immunoblotting, radioligand binding and immunoprecipitation. It was found that PSD-95 both enhanced the level of NR2A and NR2B subunit expression by approximately three-fold and induced a three-fold increase in the [3H]MK801 radioligand binding sites for NR1-1a/NR2A receptors. PSD-95 also increased the EC50 values for the L-glutamate and glycine enhancement of [3H]MK801 binding to NR1-1a/NR2A receptors by four-fold and six-fold respectively. PSD-95 however, had no effect on the affinity of NRl-la/NR2A receptors for L-glutamate and glycine as determined by [3H]CGP39653 and [3H]MDL105-519 displacement assays respectively suggesting that the reduced EC50 may be due to decreased channel gating. Deletion studies showed that both the biochemical and pharmacological effects of PDS-95 on expressed NMDA receptors were dependent upon the NR2 C-terminal ESDV motif, the PSD-95-binding domain. Further, mutagenesis of the two N-terminal cysteine residues of PSD-95 demonstrated that PSD-95/NMDA receptor clustering is necessary for the changes in NMDA receptor properties induced by PSD-95. These results suggest that the interaction between PSD-95 and native NMDA receptors may be important for the regulation of both receptor function and receptor number at post- synaptic sites.

Subjects/Keywords: 572; N-methyl-D-aspartate

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Rutter, A. R. (2001). Biochemical and pharmacological characterisation of the interaction between NMDA receptors and the scaffolding protein PSD-95. (Doctoral Dissertation). University College London (University of London). Retrieved from https://discovery.ucl.ac.uk/id/eprint/10097895/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.248043

Chicago Manual of Style (16^th Edition):

Rutter, Anthony Richard. “Biochemical and pharmacological characterisation of the interaction between NMDA receptors and the scaffolding protein PSD-95.” 2001. Doctoral Dissertation, University College London (University of London). Accessed January 20, 2021. https://discovery.ucl.ac.uk/id/eprint/10097895/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.248043.

MLA Handbook (7^th Edition):

Rutter, Anthony Richard. “Biochemical and pharmacological characterisation of the interaction between NMDA receptors and the scaffolding protein PSD-95.” 2001. Web. 20 Jan 2021.

Vancouver:

Rutter AR. Biochemical and pharmacological characterisation of the interaction between NMDA receptors and the scaffolding protein PSD-95. [Internet] [Doctoral dissertation]. University College London (University of London); 2001. [cited 2021 Jan 20]. Available from: https://discovery.ucl.ac.uk/id/eprint/10097895/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.248043.

Council of Science Editors:

Rutter AR. Biochemical and pharmacological characterisation of the interaction between NMDA receptors and the scaffolding protein PSD-95. [Doctoral Dissertation]. University College London (University of London); 2001. Available from: https://discovery.ucl.ac.uk/id/eprint/10097895/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.248043

University of Houston

17. Anderson, Marc 1981-. An Account of Chemical and Mechanical Regulation of TRPC6 Channels in Podocytes.

Degree: PhD, Biology, 2013, University of Houston

URL: http://hdl.handle.net/10657/921

► Podocytes play a dynamic role in regulating glomerular filtration. The focus here is on the regulatory mechanisms of podocyte expressed transient receptor potential 6 (TRPC6)… (more)

▼ Podocytes play a dynamic role in regulating glomerular filtration. The focus here is on the regulatory mechanisms of podocyte expressed transient receptor potential 6 (TRPC6) channels, an ion channel implicated in certain forms of proteinuric kidney disease. TRPC6 channels are polymodal and can be activated by either chemical or mechanical stimuli. Chemical stimulation is mediated by surface-expressed receptors, and the roles of angiotensin II type 1 receptors (AT1R), insulin receptors, and N-methyl-D-aspartate receptors (NMDAR) on TRPC6 activity are studied here. In acutely isolated rat glomeruli, angiotensin causes an upregulation of TRPC6 activity, and this is mediated by the Gαq /PLC pathway. This angiotensin-evoked upregulation is partially dependent on the formation of reactive oxygen species (ROS). In mouse podocyte cell lines, insulin causes upregulation of TRPC6 through increasing ROS formation via NADPH oxidase 4 (NOX4). Similarly, NMDAR activation upregulates TRPC6, albeit through NOX2. The previously uncharacterized podocyte NMDAR has unusual properties with strong physiological implications. Specifically, podocyte NMDA receptors are essentially unresponsive to L-glutamate and L-aspartate and do not show glycine-mediated potentiation. These receptors respond to the agonists L-homocysteate and D-aspartate with large ionic currents that are potentiated by D-serine. Given their resistance to L-glutamate-induced activation, podocyte NMDA receptors likely do not act in a localized glomerular signaling system. However, their response to ligands that circulate in both the normal and pathological state suggests a role for podocyte NMDA receptors in normal glomerular function. Receptor-driven upregulation of TRPC6 comprises a class of potential targets for prevention and treatment of multiple acquired kidney diseases. Independent of receptor-mediated response, TRPC6 channels are mechanosentive and can be activated by membrane deformation in both podocyte cell lines and isolated glomeruli. This mechanosensitivity is repressed by podocin, a cholesterol-binding, membrane-associated partner of the TRPC6 channel. In addition, podocin mediates diacylglycerol activation of TRPC6, suggesting that podocin determines the favored mode of TRPC6 activation in podocytes. It is possible that disruption of the podocin-TRPC6 complex at the slit diaphragm contributes to Ca2+ overload and eventual foot process effacement. Drugs that selectively target and suppress TRPC6 mechanosensitivity could potentially serve as treatments for glomerular diseases. Advisors/Committee Members: Dryer, Stuart E. (advisor), Gunaratne, Preethi H. (committee member), Sheikh-Hamad, David (committee member), Ziburkus, Jokubas (committee member).

Subjects/Keywords: Podocytes; TRPC6 channels; N-methyl-D-aspartate (NMDA); Receptors; Biology

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Anderson, M. 1. (2013). An Account of Chemical and Mechanical Regulation of TRPC6 Channels in Podocytes. (Doctoral Dissertation). University of Houston. Retrieved from http://hdl.handle.net/10657/921

Chicago Manual of Style (16^th Edition):

Anderson, Marc 1981-. “An Account of Chemical and Mechanical Regulation of TRPC6 Channels in Podocytes.” 2013. Doctoral Dissertation, University of Houston. Accessed January 20, 2021. http://hdl.handle.net/10657/921.

MLA Handbook (7^th Edition):

Anderson, Marc 1981-. “An Account of Chemical and Mechanical Regulation of TRPC6 Channels in Podocytes.” 2013. Web. 20 Jan 2021.

Vancouver:

Anderson M1. An Account of Chemical and Mechanical Regulation of TRPC6 Channels in Podocytes. [Internet] [Doctoral dissertation]. University of Houston; 2013. [cited 2021 Jan 20]. Available from: http://hdl.handle.net/10657/921.

Council of Science Editors:

Anderson M1. An Account of Chemical and Mechanical Regulation of TRPC6 Channels in Podocytes. [Doctoral Dissertation]. University of Houston; 2013. Available from: http://hdl.handle.net/10657/921

University of Debrecen

18. Birta, Eszter. Penicillium fajok morfológiájának és sejtfal-hidrolitikus enzimtermelésének vizsgálata .

Degree: DE – TEK – Természettudományi és Technológiai Kar – Biológiai és Ökológiai Intézet, 2010, University of Debrecen

URL: http://hdl.handle.net/2437/95006

► A fonalas gombák sejtfal metabolizmusának az ismerete meghatározó a fermentációs ipari termelésre nézve, hiszen a termelés sikerét nagyban befolyásolja a fonalak integritása. Ugyanakkor a patogén… (more)

Subjects/Keywords: Penicillium; sejtfal; enzim; autolízis; fragmentáció; kitináz; N-acetil-ß-D-glükózaminidáz

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Birta, E. (2010). Penicillium fajok morfológiájának és sejtfal-hidrolitikus enzimtermelésének vizsgálata . (Thesis). University of Debrecen. Retrieved from http://hdl.handle.net/2437/95006

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Birta, Eszter. “Penicillium fajok morfológiájának és sejtfal-hidrolitikus enzimtermelésének vizsgálata .” 2010. Thesis, University of Debrecen. Accessed January 20, 2021. http://hdl.handle.net/2437/95006.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Birta, Eszter. “Penicillium fajok morfológiájának és sejtfal-hidrolitikus enzimtermelésének vizsgálata .” 2010. Web. 20 Jan 2021.

Vancouver:

Birta E. Penicillium fajok morfológiájának és sejtfal-hidrolitikus enzimtermelésének vizsgálata . [Internet] [Thesis]. University of Debrecen; 2010. [cited 2021 Jan 20]. Available from: http://hdl.handle.net/2437/95006.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Birta E. Penicillium fajok morfológiájának és sejtfal-hidrolitikus enzimtermelésének vizsgálata . [Thesis]. University of Debrecen; 2010. Available from: http://hdl.handle.net/2437/95006

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

19. Tortopidou-Derieux, Kyriaki. The politics of religious experience in Fifteenth-Century Europe through an East-West encounter : a re-interpretation.

Degree: PhD, 2016, London School of Economics and Political Science (University of London)

URL: http://etheses.lse.ac.uk/3366/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.697589

► My thesis works as an experiment, or rather a series of experiments, in methods of thinking about historical material. These methods come from anthropology and… (more)

▼ My thesis works as an experiment, or rather a series of experiments, in methods of thinking about historical material. These methods come from anthropology and engage with myths and ritual, with the concept of “complementary others”, and the concept of “schismogenesis" as it has been developed by Gregory Bateson and advanced further by Marshall Sahlins. My overall goal is not to re-describe a well-researched historical event, but to explore how different ways of analysis, using different analytical frameworks, could lead to valuable explanations of the same political-cum-cultural event. The phenomenon I engage with is the last Oecumenical Council, a major religious event in the history of Councils within already schismatic societies. For this reason, I treat this Council in particular, as a ritual, unprecedented in scale and ambiguous in its inception. I am examining the structure and the return of this Event in History, and the controversies and tensions in the diachrony of East and West. I do this not only through the notion of schismo-genesis and ritual, but specifically the notion of sacrifice as developed by Maurice Bloch, in which the journey from Constantinople to Italy becomes a historical metaphor of mythical realities, regarding the Emperor John VIII Palaiologos. And finally, I explore the significance of Bessarion and complementary others within the notion of transformation and alterity. What I establish through discussions of the historical material, which span eleven centuries of history, is first of all, that there is no event without a system; that means the journey can acquire the form of the ritual. I argue that the relation between the myth and the idea of unity is dialectical in nature; the Event of a Union, which could bring peace in the one Church of Christ, from this moment of realisation becomes a fabrication, a mystery to the witnesses, and all the other myths that will be developed on the way become even more imperative and melancholic, because they seek to express a negative and unavoidable truth. The Event doesn’t portray reality any more, it exists despite it and becomes an extreme position, almost like a dream, and it justifies the vision one wished to be possible, only to show that it is untenable: the “what if it could be”; the possibility of all parts being aspirations to the whole, oecumenicity as a goal rather than unity. Overall, this thesis is about the presence of the past in the present, in relevance to the future.

Subjects/Keywords: 940.2; D History (General); GN Anthropology; N Visual arts (General)

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Tortopidou-Derieux, K. (2016). The politics of religious experience in Fifteenth-Century Europe through an East-West encounter : a re-interpretation. (Doctoral Dissertation). London School of Economics and Political Science (University of London). Retrieved from http://etheses.lse.ac.uk/3366/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.697589

Chicago Manual of Style (16^th Edition):

Tortopidou-Derieux, Kyriaki. “The politics of religious experience in Fifteenth-Century Europe through an East-West encounter : a re-interpretation.” 2016. Doctoral Dissertation, London School of Economics and Political Science (University of London). Accessed January 20, 2021. http://etheses.lse.ac.uk/3366/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.697589.

MLA Handbook (7^th Edition):

Tortopidou-Derieux, Kyriaki. “The politics of religious experience in Fifteenth-Century Europe through an East-West encounter : a re-interpretation.” 2016. Web. 20 Jan 2021.

Vancouver:

Tortopidou-Derieux K. The politics of religious experience in Fifteenth-Century Europe through an East-West encounter : a re-interpretation. [Internet] [Doctoral dissertation]. London School of Economics and Political Science (University of London); 2016. [cited 2021 Jan 20]. Available from: http://etheses.lse.ac.uk/3366/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.697589.

Council of Science Editors:

Tortopidou-Derieux K. The politics of religious experience in Fifteenth-Century Europe through an East-West encounter : a re-interpretation. [Doctoral Dissertation]. London School of Economics and Political Science (University of London); 2016. Available from: http://etheses.lse.ac.uk/3366/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.697589

University of Notre Dame

20. Shailaja Kunda. Structural and functional properties of N-methyl-d-aspartate-receptor specific antagonistic peptides from the conus species of marine snails</h1>.

Degree: Chemistry and Biochemistry, 2015, University of Notre Dame

URL: https://curate.nd.edu/show/x920ft86t62

► Conantokins, which are neuroactive peptides found in the venom of marine snails, contain post-translationally modified &gamma-carboxyglutamate residues (Gla; γ). The Gla residues are integral… (more)

▼ Conantokins, which are neuroactive peptides found in the venom of marine snails, contain post-translationally modified &gamma-carboxyglutamate residues (Gla; γ). The Gla residues are integral for their structure, function, and subunit-selective antagonism of ion channels of the N-Methyl-D-Aspartate Receptors (NMDAR). The functional heterotetramer of the receptor is composed of GluN1 and GluN2 subunits which impart specific biochemical and physiological properties to the ion channels. The optimum spacing of Gla residues in conantokins stabilize the structure when complexed to divalent ions and mediate NMDAR-subunit selective properties. In this study, the structural and antagonistic properties of conantokins ConPr-1,-2, and -3 from Conus parius and ConRl-B from Conus rolani species were studied. The Conus parius family of conantokin peptides are GluN2B selective and adopt a low properties of α-helix conformation in the presence of Mg²⁺. These peptides also display the ability to diminish downstream signaling events. ConRl-B, ConPr-2, and ConPr-3, additionally contain the post-translationally modified 4-transhydroxyproline (HyP; O) residue. The Hyp10 residue in ConRl-B, not only changes the Gla positioning in the C-terminal part of ConRl-B, but also affects the structural properties of the peptide. A combination of biophysical techniques, e.g., CD, ¹H NMR and ITC, was employed to study the structure and metal binding properties of Mg²⁺/ConRl-B. The structure determined by high-field 1H NMR, shows disruption in the α-helix due to HyP10 further interfering with Mg²⁺-binding, thus resulting in solvent accessible backbone amide protons. To assess the role of HyP and the molecular requisites for the unique structural and functional properties of ConRl-B, mutant peptides, ConG[10 ▼O] and ConRl-B[ΔKAO▼NQ] were synthesized. Although, the 3D structure and Mg²⁺ binding abilities of ConRl-B[ΔKAO▼NQ] were similar to Con-G, this peptide displays complete non-selectivity towards NMDAR. Local disruption of the &#945-helix backbone in Con-G on the introduction of HyP, differs from that of ConRl-B. Additionally, Con-G[10 ▼O] loses selectivity towards ion channels containing the GluN2B subunit. These results suggest that the natural occurrence of HyP in the ConRl-B backbone is important for high GluN2B selectivity. In conclusion, the presence of HyP residue changes the structural and functional properties of conantokins. Advisors/Committee Members: Dr. Anthony S. Serianni, Committee Member, Dr. Francis. J. Castellino, Committee Chair, Dr. Brian M. Baker, Committee Member, Dr. Robert Stahelin, Committee Member.

Subjects/Keywords: N-methyl-d-aspartate-receptors; antagonistic; conus species

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Kunda, S. (2015). Structural and functional properties of N-methyl-d-aspartate-receptor specific antagonistic peptides from the conus species of marine snails</h1>. (Thesis). University of Notre Dame. Retrieved from https://curate.nd.edu/show/x920ft86t62

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Kunda, Shailaja. “Structural and functional properties of N-methyl-d-aspartate-receptor specific antagonistic peptides from the conus species of marine snails</h1>.” 2015. Thesis, University of Notre Dame. Accessed January 20, 2021. https://curate.nd.edu/show/x920ft86t62.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Kunda, Shailaja. “Structural and functional properties of N-methyl-d-aspartate-receptor specific antagonistic peptides from the conus species of marine snails</h1>.” 2015. Web. 20 Jan 2021.

Vancouver:

Kunda S. Structural and functional properties of N-methyl-d-aspartate-receptor specific antagonistic peptides from the conus species of marine snails</h1>. [Internet] [Thesis]. University of Notre Dame; 2015. [cited 2021 Jan 20]. Available from: https://curate.nd.edu/show/x920ft86t62.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Kunda S. Structural and functional properties of N-methyl-d-aspartate-receptor specific antagonistic peptides from the conus species of marine snails</h1>. [Thesis]. University of Notre Dame; 2015. Available from: https://curate.nd.edu/show/x920ft86t62

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

21. Younis, Vincent. Att vara välkomen men ändå inte : “Povertyisthemotherofcrime”/MarcusAurelius.

Degree: Care and Social Welfare, 2017, Mälardalen University

URL: http://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-38412

► Studien undersöker invånare och verksammas upplevelser av ett, enligt en rapport frånunderrättelseenheten, utsatt bostadsområde i Västerås. För att besvara frågeställningen har vigenomfört 14 intervjuer… (more)

Subjects/Keywords: u n g d o m a r; b o s t a d s o m r å d e; s y s s e l s ä t t n i n g; s p r i d n i n g; b r o t t; t r y g g h e t; Social Sciences; Samhällsvetenskap

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Younis, V. (2017). Att vara välkomen men ändå inte : “Povertyisthemotherofcrime”/MarcusAurelius. (Thesis). Mälardalen University. Retrieved from http://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-38412

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Younis, Vincent. “Att vara välkomen men ändå inte : “Povertyisthemotherofcrime”/MarcusAurelius.” 2017. Thesis, Mälardalen University. Accessed January 20, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-38412.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Younis, Vincent. “Att vara välkomen men ändå inte : “Povertyisthemotherofcrime”/MarcusAurelius.” 2017. Web. 20 Jan 2021.

Vancouver:

Younis V. Att vara välkomen men ändå inte : “Povertyisthemotherofcrime”/MarcusAurelius. [Internet] [Thesis]. Mälardalen University; 2017. [cited 2021 Jan 20]. Available from: http://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-38412.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Younis V. Att vara välkomen men ändå inte : “Povertyisthemotherofcrime”/MarcusAurelius. [Thesis]. Mälardalen University; 2017. Available from: http://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-38412

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Dundee

22. Snaith, Mark Ian. Argument revision and its role in dialogue.

Degree: PhD, 2013, University of Dundee

URL: https://discovery.dundee.ac.uk/en/studentTheses/3dfef7e9-fbc0-418a-acdf-459ccd705bbd ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.578914

► In this thesis, a model for argument revision is presented, in terms of the expansion and contraction of a system of structured argumentation. At its… (more)

▼ In this thesis, a model for argument revision is presented, in terms of the expansion and contraction of a system of structured argumentation. At its core, the model uses the belief revision concept of minimal change, but without requiring a pre-determined entrenchment ordering to establish minimality. In the first part of the thesis, a model for argument revision is defined and described. Specified in terms of the ASPIC\+ framework for argumentation, the model is divided into two main concepts: argument expansion, whose goal is to make certain arguments acceptable in the system, possibly by adding them; and argument contraction, whose goal is to make certain arguments unacceptable in the system, possibly by removing them. The goal of a revision process can be achieved in multiple different ways, thus a method of choosing which, based on measures of minimal change, is also specified. The second part of the thesis demonstrates two applications of the model in the context of multi-agent dialogue. The first is used to assist a participant when faced with a need to update its commitment store during persuasion dialogue, while the second shows how a participant can use argument revision techniques to both assess and maintain a lie.The main contributions of the thesis are twofold. First, the characterisation of a model for argument revision, based on established belief revision principles but with a key difference. The model for argument revision demonstrates how it is possible to use measurable effects on the system when determining minimal change instead of relying on a pre-determined, qualitative entrenchment ordering.Second, the thesis demonstrates two applications of argument revision in dialogue. The first is in assisting an agent in retracting a commitment that has been defeated, and for which it can offer no defence. When retracting a claim, the participant may also be required to retract other claims from which the defeated one is a consequence. Applying argument revision techniques allow the participant to reason about what constitutes a minimal set of retractions, in terms of current commitments and potential future communications in the dialogue.The second dialogical application relates to the opposite of retraction; instead of choosing to retract an undefended claim, the participant could instead choose to lie in order to defend it. Argument revision allows the participant to not only assess whether or not lying is ``minimal'' (compared to retracting), but to also to maintain the lie, by using the measures of minimal change.Overall, the thesis shows that not only is justifiable argument revision possible without relying on a pre-determined entrenchment ordering, it is also a powerful tool for participants in a dialogue, assisting with dialogue move selection.

Subjects/Keywords: 004; Argumentation; Argument revsion; Belief revision; Argument

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Snaith, M. I. (2013). Argument revision and its role in dialogue. (Doctoral Dissertation). University of Dundee. Retrieved from https://discovery.dundee.ac.uk/en/studentTheses/3dfef7e9-fbc0-418a-acdf-459ccd705bbd ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.578914

Chicago Manual of Style (16^th Edition):

Snaith, Mark Ian. “Argument revision and its role in dialogue.” 2013. Doctoral Dissertation, University of Dundee. Accessed January 20, 2021. https://discovery.dundee.ac.uk/en/studentTheses/3dfef7e9-fbc0-418a-acdf-459ccd705bbd ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.578914.

MLA Handbook (7^th Edition):

Snaith, Mark Ian. “Argument revision and its role in dialogue.” 2013. Web. 20 Jan 2021.

Vancouver:

Snaith MI. Argument revision and its role in dialogue. [Internet] [Doctoral dissertation]. University of Dundee; 2013. [cited 2021 Jan 20]. Available from: https://discovery.dundee.ac.uk/en/studentTheses/3dfef7e9-fbc0-418a-acdf-459ccd705bbd ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.578914.

Council of Science Editors:

Snaith MI. Argument revision and its role in dialogue. [Doctoral Dissertation]. University of Dundee; 2013. Available from: https://discovery.dundee.ac.uk/en/studentTheses/3dfef7e9-fbc0-418a-acdf-459ccd705bbd ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.578914

23. Khartabil, Dana. Visualisation techniques to facilitate argument exploration.

Degree: PhD, 2020, Edinburgh Napier University

URL: https://doi.org/10.17869/enu.2020.2694675 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.818580

► Visualisation is a graphical representation that is used to aid understanding and gain insight into information. Similarly, visualising arguments can help people to explore argument… (more)

Subjects/Keywords: visualisation; argument; argument data; user understanding

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Khartabil, D. (2020). Visualisation techniques to facilitate argument exploration. (Doctoral Dissertation). Edinburgh Napier University. Retrieved from https://doi.org/10.17869/enu.2020.2694675 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.818580

Chicago Manual of Style (16^th Edition):

Khartabil, Dana. “Visualisation techniques to facilitate argument exploration.” 2020. Doctoral Dissertation, Edinburgh Napier University. Accessed January 20, 2021. https://doi.org/10.17869/enu.2020.2694675 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.818580.

MLA Handbook (7^th Edition):

Khartabil, Dana. “Visualisation techniques to facilitate argument exploration.” 2020. Web. 20 Jan 2021.

Vancouver:

Khartabil D. Visualisation techniques to facilitate argument exploration. [Internet] [Doctoral dissertation]. Edinburgh Napier University; 2020. [cited 2021 Jan 20]. Available from: https://doi.org/10.17869/enu.2020.2694675 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.818580.

Council of Science Editors:

Khartabil D. Visualisation techniques to facilitate argument exploration. [Doctoral Dissertation]. Edinburgh Napier University; 2020. Available from: https://doi.org/10.17869/enu.2020.2694675 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.818580

Universidade de Brasília

24. Mônica de Oliveira Santos. Caracterização da N-acetil-ß-D-glicosaminidase de Paracoccidioides brasiliensis.

Degree: 2007, Universidade de Brasília

URL: http://bdtd.bce.unb.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=2760

►

The full-length cDNA Pbnag enconding a N-acetyl-β-Dglucosaminidase (NAG) GeneBank accession number AF 419158 of Paracoccidioides brasiliensis was characterized and classified as a NAG belonging to… (more)

▼

The full-length cDNA Pbnag enconding a N-acetyl-β-Dglucosaminidase (NAG) GeneBank accession number AF 419158 of Paracoccidioides brasiliensis was characterized and classified as a NAG belonging to the glycosil hydrolase family 20. The PbNAG was expressed in Escherichia coli and purified to homogeneity by affinity chromatography on glutathione-Sepharose 4B. SDS-PAGE analysis revealed the presence of one protein species with molecular mass estimated of 64.8 kDa. Immunoelectron microscopy demonstrated the presence of the native protein in the cell wall of P. brasiliensis. The recombinant protein was evaluated regarding to its kinetics properties The Km and Vmax values for the enzyme using ρ- nitrophenyl-β-D-N-acetylglucosamine (ρNP-GlcNAc) as substrate, were 0.112 mM and 0.0017 mM, respectively. The pH optimum for the enzyme was 4.4 and maximum activity was obtained at 37 C. The enzyme activity was poorly affected by glucose and was inhibited by glucosamine, Nacetylglucosaminide. The studies show that PbNAG is present in the cell wall of yeast cells of P. brasiliensis suggesting its potential role in the fungal cell wall additionally.

Um cDNA (Pbnag, n de acesso GenBank AF 419158) codificante para N-acetil-β-D-glicosaminidase (NAG) de Paracoccidioides brasiliensis, isolado Pb 01 (ATCC MYA826) foi caracterizado e classificado como uma enzima pertencente à família 20 de glicosil hidrolase. PbNAG foi clonado em pGEX-4T3 e expresso em Escherichia coli. A análise em gel apresentou a presença de uma proteína de massa molecular estimada em 64,8 kDA. A proteína expressa foi purificada em resina glutationa-sepharose 4B e utilizada para produção de anticorpo policlonal. O anticorpo produzido anti-PbNAG apresentou reação com a proteína nativa, em extrato total, de micélio e levedura de P. brasiliensis. Na imunocitolocalização o anticorpo anti-PbNAG reagiu com a proteína NAG nativa presente na parede de células leveduriformes P. brasiliensis. A enzima recombinante PbNAG foi caracterizada apresentando afinidade pelo substrato ρ-nitrofenil-β-D-N-acetilglucosamina (ρNP-GlcNAc), com Km de 0.112 mM, Vmax de 0.0017 mM min-1 mg proteina-1, temperatura ótima de 37C e pH ótimo de 4.4. A enzima foi pouco inibida por glicose e apresentou inibição por glicosamina, N-acetilglicosamina. Os estudos mostram que PbNAG está presente na parede celular de células leveduriformes de P. brasiliensis, sugerindo seu papel no metabolismo da parede fúngica.

Advisors/Committee Members: Cirano Jose Ulhoa, Maristela Pereira, Jaime Martins de Santana, Carlos Roberto Felix, Célia Maria de Almeida Soares.

Subjects/Keywords: Paracoccidioides brasiliensis; N-acetil-β; -Dglicosaminidase; parede celular; Paracoccidioides brasiliensis; N-acetyl-β; -D-glucosaminidase; cell wall; CIENCIAS DA SAUDE

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Santos, M. d. O. (2007). Caracterização da N-acetil-ß-D-glicosaminidase de Paracoccidioides brasiliensis. (Thesis). Universidade de Brasília. Retrieved from http://bdtd.bce.unb.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=2760

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Santos, Mônica de Oliveira. “Caracterização da N-acetil-ß-D-glicosaminidase de Paracoccidioides brasiliensis.” 2007. Thesis, Universidade de Brasília. Accessed January 20, 2021. http://bdtd.bce.unb.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=2760.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Santos, Mônica de Oliveira. “Caracterização da N-acetil-ß-D-glicosaminidase de Paracoccidioides brasiliensis.” 2007. Web. 20 Jan 2021.

Vancouver:

Santos MdO. Caracterização da N-acetil-ß-D-glicosaminidase de Paracoccidioides brasiliensis. [Internet] [Thesis]. Universidade de Brasília; 2007. [cited 2021 Jan 20]. Available from: http://bdtd.bce.unb.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=2760.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Santos MdO. Caracterização da N-acetil-ß-D-glicosaminidase de Paracoccidioides brasiliensis. [Thesis]. Universidade de Brasília; 2007. Available from: http://bdtd.bce.unb.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=2760

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Victoria University of Wellington

25. Che Zaudin, Nurul Akmar Binti. Using nanotechnology to enhance plant growth.

Degree: 2016, Victoria University of Wellington

URL: http://hdl.handle.net/10063/8206

► Efficient and effective delivery of fertilisers, herbicides, pesticides and growth regulating compounds to plants is the subject of much ongoing research. The objective of this… (more)

▼ Efficient and effective delivery of fertilisers, herbicides, pesticides and growth regulating compounds to plants is the subject of much ongoing research. The objective of this research was to develop nano-formulations for delivery of compounds to plants. Two formulations were developed: the first was solution-based focused on encapsulation of the active ingredient in a nanoemulsion. Nanoemulsions should be ideal for facilitating transfer of compounds to plant leaves as their size correlates well with the nanoscale surface features of leaves, achieving significantly greater total contact area between the oil droplets and the leaves. The second nano-formulation was solid-state based, focused on locating the active ingredient within the tubules of a nanotube clay. For proof-of-concept two synthetic plant hormones, N-phenyl-N‘-(2-chloro-4-pyridyl)urea (CPPU) or forchlorfenuron, a synthetic cytokinin, and 2,4-dichlorophenoxyacetic acid (2,4-D), a synthetic auxin, were chosen for encapsulation. CPPU is a phenylurea derivative that shows strikingly strong cytokinin-like activity in plants, including delaying senescence. It is highly water insoluble, but soluble in organic solvents. It is widely used in a variety of crops, particularly kiwifruit and table grapes. Delivery of CPPU safely, efficiently and at the appropriate dosage is a priority as overdosing or incorrect timing of application causes detrimental effects on fruit firmness and other quality attributes. Auxins are also a group of plant hormone. 2,4-D is a synthetic auxin which has been widely used at high concentrations as a herbicide, at medium concentrations for fruit thinning, and at low concentrations promotes root initiation, but at even lower concentrations promote root elongation. Consequently, careful control of dosage is required to obtain the desired effect. The nanoemulsion system developed was water/polysorbate 80/glycerol/soybean oil. The active ingredient, CPPU, was incorporated into the nanoemulsion via the oil phase in a pre-concentrate which was then crash diluted to yield the final nanoemulsion. Nanoemulsions are created only when the concentrate is located in the bicontinuous or oil-in-water microemulsion regions of the phase diagram. The droplet size of the nanoemulsions was measured using dynamic light scattering with droplets ranging in size from 30 – 100 nm. The CPPU-loaded nanoemulsions were stable for more than three days. To determine if the nanoemulsion was an effective delivery system, a leaf senescence bioassay was conducted to test the senescence-delaying effect of the CPPU-loaded nanoemulsions when applied to explants. The nanoemulsions were applied directly to the leaves of dwarf bean explants. Chlorophyll was extracted from the leaves and measured spectrophotometrically before and several days following treatment. The CPPU-loaded nanoemulsions enhanced the effectiveness of CPPU in delaying leaf senescence compared with the control experiments, including direct application of CPPU. A >10-fold reduction in CPPU concentration was… Advisors/Committee Members: McGrath, Kate, Jameson, Paula.

Subjects/Keywords: Nanoemulsion; Halloysite clay nanotubes; Cytokinin; Auxin; CPPU; N-phenyl-N‘-(2-chloro-4-pyridyl)urea; 2,4-D; Slow release; Chlorophyll assay

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Che Zaudin, N. A. B. (2016). Using nanotechnology to enhance plant growth. (Doctoral Dissertation). Victoria University of Wellington. Retrieved from http://hdl.handle.net/10063/8206

Chicago Manual of Style (16^th Edition):

Che Zaudin, Nurul Akmar Binti. “Using nanotechnology to enhance plant growth.” 2016. Doctoral Dissertation, Victoria University of Wellington. Accessed January 20, 2021. http://hdl.handle.net/10063/8206.

MLA Handbook (7^th Edition):

Che Zaudin, Nurul Akmar Binti. “Using nanotechnology to enhance plant growth.” 2016. Web. 20 Jan 2021.

Vancouver:

Che Zaudin NAB. Using nanotechnology to enhance plant growth. [Internet] [Doctoral dissertation]. Victoria University of Wellington; 2016. [cited 2021 Jan 20]. Available from: http://hdl.handle.net/10063/8206.

Council of Science Editors:

Che Zaudin NAB. Using nanotechnology to enhance plant growth. [Doctoral Dissertation]. Victoria University of Wellington; 2016. Available from: http://hdl.handle.net/10063/8206

Univerzitet u Beogradu

26. Radovanović, Lidija D., 1980-. Kompleksi elemenata d-bloka sa aromatičnim O,O- I N, N-donorskim ligandima: sinteza, struktura, svojstva i primena.

Degree: Tehnološko-metalurški fakultet, 2018, Univerzitet u Beogradu

URL: https://fedorabg.bg.ac.rs/fedora/get/o:18860/bdef:Content/get

►

Tehnološko inženjerstvo - Inženjerstvo materijala / Technological Engineering - Materials Engineering

Reakcijom izmene liganada različitim metodama sinteze dobijeno je 22 ternarna kompleksa elemenata d-bloka [Mn(II),… (more)

Subjects/Keywords: complexes of d-block elements; crystal structures; O; O-donor ligands; N; N-donor ligands; magnetism; photoluminescence; antimicrobial activity; nanomaterials

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Radovanović, Lidija D., 1. (2018). Kompleksi elemenata d-bloka sa aromatičnim O,O- I N, N-donorskim ligandima: sinteza, struktura, svojstva i primena. (Thesis). Univerzitet u Beogradu. Retrieved from https://fedorabg.bg.ac.rs/fedora/get/o:18860/bdef:Content/get

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Radovanović, Lidija D., 1980-. “Kompleksi elemenata d-bloka sa aromatičnim O,O- I N, N-donorskim ligandima: sinteza, struktura, svojstva i primena.” 2018. Thesis, Univerzitet u Beogradu. Accessed January 20, 2021. https://fedorabg.bg.ac.rs/fedora/get/o:18860/bdef:Content/get.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Radovanović, Lidija D., 1980-. “Kompleksi elemenata d-bloka sa aromatičnim O,O- I N, N-donorskim ligandima: sinteza, struktura, svojstva i primena.” 2018. Web. 20 Jan 2021.

Vancouver:

Radovanović, Lidija D. 1. Kompleksi elemenata d-bloka sa aromatičnim O,O- I N, N-donorskim ligandima: sinteza, struktura, svojstva i primena. [Internet] [Thesis]. Univerzitet u Beogradu; 2018. [cited 2021 Jan 20]. Available from: https://fedorabg.bg.ac.rs/fedora/get/o:18860/bdef:Content/get.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Radovanović, Lidija D. 1. Kompleksi elemenata d-bloka sa aromatičnim O,O- I N, N-donorskim ligandima: sinteza, struktura, svojstva i primena. [Thesis]. Univerzitet u Beogradu; 2018. Available from: https://fedorabg.bg.ac.rs/fedora/get/o:18860/bdef:Content/get

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Victoria University of Wellington

27. Che Zaudin, Nurul Akmar Binti. Using nanotechnology to enhance plant growth.

Degree: 2016, Victoria University of Wellington

URL: http://hdl.handle.net/10063/8786

► Efficient and effective delivery of fertilisers, herbicides, pesticides and growth regulating compounds to plants is the subject of much ongoing research. The objective of this… (more)

▼ Efficient and effective delivery of fertilisers, herbicides, pesticides and growth regulating compounds to plants is the subject of much ongoing research. The objective of this research was to develop nano-formulations for delivery of compounds to plants. Two formulations were developed: the first was solution-based focused on encapsulation of the active ingredient in a nanoemulsion. Nanoemulsions should be ideal for facilitating transfer of compounds to plant leaves as their size correlates well with the nanoscale surface features of leaves, achieving significantly greater total contact area between the oil droplets and the leaves. The second nano-formulation was solid-state based, focused on locating the active ingredient within the tubules of a nanotube clay. For proof-of-concept two synthetic plant hormones, N-phenyl-N‘-(2-chloro-4-pyridyl)urea (CPPU) or forchlorfenuron, a synthetic cytokinin, and 2,4-dichlorophenoxyacetic acid (2,4-D), a synthetic auxin, were chosen for encapsulation. CPPU is a phenylurea derivative that shows strikingly strong cytokinin-like activity in plants, including delaying senescence. It is highly water insoluble, but soluble in organic solvents. It is widely used in a variety of crops, particularly kiwifruit and table grapes. Delivery of CPPU safely, efficiently and at the appropriate dosage is a priority as overdosing or incorrect timing of application causes detrimental effects on fruit firmness and other quality attributes. Auxins are also a group of plant hormone. 2,4-D is a synthetic auxin which has been widely used at high concentrations as a herbicide, at medium concentrations for fruit thinning, and at low concentrations promotes root initiation, but at even lower concentrations promote root elongation. Consequently, careful control of dosage is required to obtain the desired effect. The nanoemulsion system developed was water/polysorbate 80/glycerol/soybean oil. The active ingredient, CPPU, was incorporated into the nanoemulsion via the oil phase in a pre-concentrate which was then crash diluted to yield the final nanoemulsion. Nanoemulsions are created only when the concentrate is located in the bicontinuous or oil-in-water microemulsion regions of the phase diagram. The droplet size of the nanoemulsions was measured using dynamic light scattering with droplets ranging in size from 30 – 100 nm. The CPPU-loaded nanoemulsions were stable for more than three days. To determine if the nanoemulsion was an effective delivery system, a leaf senescence bioassay was conducted to test the senescence-delaying effect of the CPPU-loaded nanoemulsions when applied to explants. The nanoemulsions were applied directly to the leaves of dwarf bean explants. Chlorophyll was extracted from the leaves and measured spectrophotometrically before and several days following treatment. The CPPU-loaded nanoemulsions enhanced the effectiveness of CPPU in delaying leaf senescence compared with the control experiments, including direct application of CPPU. A >10-fold reduction in CPPU concentration was… Advisors/Committee Members: McGrath, Kate, Jameson, Paula.

Subjects/Keywords: Nanoemulsion; Halloysite clay nanotubes; Cytokinin; Auxin; CPPU; N-phenyl-N‘-(2-chloro-4-pyridyl)urea; 2,4-D; Slow release; Chlorophyll assay

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Che Zaudin, N. A. B. (2016). Using nanotechnology to enhance plant growth. (Doctoral Dissertation). Victoria University of Wellington. Retrieved from http://hdl.handle.net/10063/8786

Chicago Manual of Style (16^th Edition):

Che Zaudin, Nurul Akmar Binti. “Using nanotechnology to enhance plant growth.” 2016. Doctoral Dissertation, Victoria University of Wellington. Accessed January 20, 2021. http://hdl.handle.net/10063/8786.

MLA Handbook (7^th Edition):

Che Zaudin, Nurul Akmar Binti. “Using nanotechnology to enhance plant growth.” 2016. Web. 20 Jan 2021.

Vancouver:

Che Zaudin NAB. Using nanotechnology to enhance plant growth. [Internet] [Doctoral dissertation]. Victoria University of Wellington; 2016. [cited 2021 Jan 20]. Available from: http://hdl.handle.net/10063/8786.

Council of Science Editors:

Che Zaudin NAB. Using nanotechnology to enhance plant growth. [Doctoral Dissertation]. Victoria University of Wellington; 2016. Available from: http://hdl.handle.net/10063/8786

28. Hahn, Jacob Andrew. Zoltán Kodály’s Op. 9, Öt dal: a historical, textual, and musical analysis with translations and IPA.

Degree: 2020, NC Docks

URL: http://libres.uncg.edu/ir/uncg/f/Hahn_uncg_0154D_12975.pdf

► Zoltán Kodály is primarily known outside of Hungary for his pedagogical work. However, his compositions should also be recognized for their excellence. His art songs… (more)

Subjects/Keywords: Koda´ly; Zolta´n; $d 1882-1967. $t Dalok; $n op. 9 $x History and criticism

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Hahn, J. A. (2020). Zoltán Kodály’s Op. 9, Öt dal: a historical, textual, and musical analysis with translations and IPA. (Thesis). NC Docks. Retrieved from http://libres.uncg.edu/ir/uncg/f/Hahn_uncg_0154D_12975.pdf

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Hahn, Jacob Andrew. “Zoltán Kodály’s Op. 9, Öt dal: a historical, textual, and musical analysis with translations and IPA.” 2020. Thesis, NC Docks. Accessed January 20, 2021. http://libres.uncg.edu/ir/uncg/f/Hahn_uncg_0154D_12975.pdf.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Hahn, Jacob Andrew. “Zoltán Kodály’s Op. 9, Öt dal: a historical, textual, and musical analysis with translations and IPA.” 2020. Web. 20 Jan 2021.

Vancouver:

Hahn JA. Zoltán Kodály’s Op. 9, Öt dal: a historical, textual, and musical analysis with translations and IPA. [Internet] [Thesis]. NC Docks; 2020. [cited 2021 Jan 20]. Available from: http://libres.uncg.edu/ir/uncg/f/Hahn_uncg_0154D_12975.pdf.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Hahn JA. Zoltán Kodály’s Op. 9, Öt dal: a historical, textual, and musical analysis with translations and IPA. [Thesis]. NC Docks; 2020. Available from: http://libres.uncg.edu/ir/uncg/f/Hahn_uncg_0154D_12975.pdf

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

29. NC DOCKS at The University of North Carolina at Greensboro; Steele, Christopher Daniel. Tonal and formal blurring in Faure's Piano Trio Op. 120.

Degree: 2012, NC Docks

URL: http://libres.uncg.edu/ir/uncg/f/SteeleC_uncg_0154D_10916.pdf

► This study presents an analytical discussion of blurring techniques found in the first movement of Fauré's Piano Trio Op. 120. After a brief overview of… (more)

Subjects/Keywords: Faure´; Gabriel; $d 1845-1924. $t Trio; $m piano; strings; $n op. 120; $r D minor $x Analysis; appreciation

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

NC DOCKS at The University of North Carolina at Greensboro; Steele, C. D. (2012). Tonal and formal blurring in Faure's Piano Trio Op. 120. (Thesis). NC Docks. Retrieved from http://libres.uncg.edu/ir/uncg/f/SteeleC_uncg_0154D_10916.pdf

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

NC DOCKS at The University of North Carolina at Greensboro; Steele, Christopher Daniel. “Tonal and formal blurring in Faure's Piano Trio Op. 120.” 2012. Thesis, NC Docks. Accessed January 20, 2021. http://libres.uncg.edu/ir/uncg/f/SteeleC_uncg_0154D_10916.pdf.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

NC DOCKS at The University of North Carolina at Greensboro; Steele, Christopher Daniel. “Tonal and formal blurring in Faure's Piano Trio Op. 120.” 2012. Web. 20 Jan 2021.

Vancouver:

NC DOCKS at The University of North Carolina at Greensboro; Steele CD. Tonal and formal blurring in Faure's Piano Trio Op. 120. [Internet] [Thesis]. NC Docks; 2012. [cited 2021 Jan 20]. Available from: http://libres.uncg.edu/ir/uncg/f/SteeleC_uncg_0154D_10916.pdf.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

NC DOCKS at The University of North Carolina at Greensboro; Steele CD. Tonal and formal blurring in Faure's Piano Trio Op. 120. [Thesis]. NC Docks; 2012. Available from: http://libres.uncg.edu/ir/uncg/f/SteeleC_uncg_0154D_10916.pdf

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

30. Arko, Anja. Structural models of Franz Schubert’s Wanderer fantasy: fantasy, symphonic poem, and two-dimensional sonata form.

Degree: 2020, NC Docks

URL: http://libres.uncg.edu/ir/uncg/f/Arko_uncg_0154D_12984.pdf

► The Wanderer Fantasy integrates qualities derived from three different genres: fantasy, tone poem, and sonata, and thus demonstrates a fusion of compositional styles that culminates… (more)

Subjects/Keywords: Schubert; Franz; $d 1797-1828. $t Fantasien; $m piano; $n D. 760; $r C major $x History and criticism

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Arko, A. (2020). Structural models of Franz Schubert’s Wanderer fantasy: fantasy, symphonic poem, and two-dimensional sonata form. (Thesis). NC Docks. Retrieved from http://libres.uncg.edu/ir/uncg/f/Arko_uncg_0154D_12984.pdf

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Arko, Anja. “Structural models of Franz Schubert’s Wanderer fantasy: fantasy, symphonic poem, and two-dimensional sonata form.” 2020. Thesis, NC Docks. Accessed January 20, 2021. http://libres.uncg.edu/ir/uncg/f/Arko_uncg_0154D_12984.pdf.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Arko, Anja. “Structural models of Franz Schubert’s Wanderer fantasy: fantasy, symphonic poem, and two-dimensional sonata form.” 2020. Web. 20 Jan 2021.

Vancouver:

Arko A. Structural models of Franz Schubert’s Wanderer fantasy: fantasy, symphonic poem, and two-dimensional sonata form. [Internet] [Thesis]. NC Docks; 2020. [cited 2021 Jan 20]. Available from: http://libres.uncg.edu/ir/uncg/f/Arko_uncg_0154D_12984.pdf.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Arko A. Structural models of Franz Schubert’s Wanderer fantasy: fantasy, symphonic poem, and two-dimensional sonata form. [Thesis]. NC Docks; 2020. Available from: http://libres.uncg.edu/ir/uncg/f/Arko_uncg_0154D_12984.pdf

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Open Access Theses and Dissertations