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University of Melbourne
1.
Ranjan, Rajesh.
Automatic assessment system for quantification and classification of pure tremor and Parkinsonian tremor.
Degree: 2019, University of Melbourne
URL: http://hdl.handle.net/11343/224228
► With the changing lifestyle and environment around us, the prevalence of the critical and incurable disease has proliferated. One such condition is the neurological disorder…
(more)
▼ With the changing lifestyle and environment around us, the prevalence of the critical and incurable disease has proliferated. One such condition is the neurological disorder which is rampant among the old age population and is increasing at an unstoppable rate. Most of the neurological disorder patients suffer from some movement disorder affecting the movement of their body parts. Tremor is the most common movement disorder which is prevalent in such patients that infect the upper or lower limbs or both extremities. The tremor symptoms are commonly visible in Parkinson’s disease patient, and it can also be a pure tremor(essential tremor). Tremor is an almost incurable disease, and it gets worse with the increase in age and improper diagnosis. The clinicians provide the diagnosis which can only limit the severity, but the patients have to visit the doctor frequently. The patients suffering from tremor face enormous trouble in performing the daily activity, and they always need a caretaker for assistance. In most of the countries especially which are developing or underdeveloped due to the inadequate facility or lack of rehabilitation centers for neurological disorder patient the monitoring and adequate assistance are not possible. Moreover, the improper coordination of the patient with the doctors could lead to a severer case of tremor and early ambulatory condition.
In the clinics, the assessment of tremor is done through a manual clinical rating task such as Unified Parkinson’s disease motor rating scale which is time taking and cumbersome. Neurologists have also affirmed a challenge in differentiating a Parkinsonian tremor with the pure tremor which is essential in providing an accurate diagnosis. Therefore, there is a need to develop a monitoring and assistive tool for the tremor patient that keep on checking their health condition by coordinating them with the clinicians and caretakers for early diagnosis and assistance in performing the daily activity. Automatic quantification of severity scores can help the clinician to accurately and quickly recognize the severity of tremor in the patient. Hence they can provide the necessary quantity of dosage of drugs to the patient. Continuous quantification of severity of tremor can also help the clinician and caretakers in assessing the improvement in patients concerning the diagnosis being assigned to them. Thereby the dosage of drugs can be reduced or increased accordingly, and the caretakers can provide less or more frequent assistance.
The current trends in technological advances have been assertive in solving critical healthcare problems. Various devices integrated with the machine learning tools can prove highly beneficial in building an automatic assessment tool for quantification of tremor severity in agreement to the clinical rating scale. In our research, we focus on developing a system for automatic quantification and classification of tremor which can provide accurate severity scores and differentiate the pure tremor from the Parkinsonian tremor using…
Subjects/Keywords: Parkinsonian tremor
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APA (6th Edition):
Ranjan, R. (2019). Automatic assessment system for quantification and classification of pure tremor and Parkinsonian tremor. (Masters Thesis). University of Melbourne. Retrieved from http://hdl.handle.net/11343/224228
Chicago Manual of Style (16th Edition):
Ranjan, Rajesh. “Automatic assessment system for quantification and classification of pure tremor and Parkinsonian tremor.” 2019. Masters Thesis, University of Melbourne. Accessed January 20, 2021.
http://hdl.handle.net/11343/224228.
MLA Handbook (7th Edition):
Ranjan, Rajesh. “Automatic assessment system for quantification and classification of pure tremor and Parkinsonian tremor.” 2019. Web. 20 Jan 2021.
Vancouver:
Ranjan R. Automatic assessment system for quantification and classification of pure tremor and Parkinsonian tremor. [Internet] [Masters thesis]. University of Melbourne; 2019. [cited 2021 Jan 20].
Available from: http://hdl.handle.net/11343/224228.
Council of Science Editors:
Ranjan R. Automatic assessment system for quantification and classification of pure tremor and Parkinsonian tremor. [Masters Thesis]. University of Melbourne; 2019. Available from: http://hdl.handle.net/11343/224228

Brigham Young University
2.
Corie, Thomas Henry.
Simulated Tremor Propagation in the Upper Limb: From Muscle Activity to Joint Displacement.
Degree: MS, 2018, Brigham Young University
URL: https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=7777&context=etd
► Although tremor is the most common movement disorder, there are few non-invasive treatment options. One of the obstacles to creating effective tremor suppression devices is…
(more)
▼ Although tremor is the most common movement disorder, there are few non-invasive treatment options. One of the obstacles to creating effective tremor suppression devices is our lack of understanding regarding where tremor originates (which muscles), how it propagates through the limb (to which degrees of freedom, DOF), and where it manifests most severely (which DOF). To investigate these questions, we created a simple, linear time-invariant model to simulate tremor, with tremorogenic muscle activity input (in the 15 major superficial muscles from the shoulder to the wrist) and joint displacement output (in the 7 major upper limb DOF). The model included excitation-contraction dynamics, musculoskeletal geometry (muscle moment arms) and the mechanical impedance (inertia, damping, and stiffness) of the limb. From our simulation results, we determined four principles of tremor propagation. First, the distribution of tremor depends strongly on musculoskeletal dynamics. Second, the spreading of tremor is due to inertial coupling (primarily) and musculoskeletal geometry (secondarily). Third, tremor spreads narrowly in the sense that most of the tremor caused by a muscle occurs in a small number of DOF. Lastly, assuming uniform distribution of tremorogenic activity among upper-limb muscles, tremor increases proximal-distally, and the contribution from muscles increases proximal-distally.
Subjects/Keywords: tremor; tremor characterization; tremor distribution; tremor propagation; upper limb; degrees of freedom; Mechanical Engineering
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❌
APA ·
Chicago ·
MLA ·
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APA (6th Edition):
Corie, T. H. (2018). Simulated Tremor Propagation in the Upper Limb: From Muscle Activity to Joint Displacement. (Masters Thesis). Brigham Young University. Retrieved from https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=7777&context=etd
Chicago Manual of Style (16th Edition):
Corie, Thomas Henry. “Simulated Tremor Propagation in the Upper Limb: From Muscle Activity to Joint Displacement.” 2018. Masters Thesis, Brigham Young University. Accessed January 20, 2021.
https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=7777&context=etd.
MLA Handbook (7th Edition):
Corie, Thomas Henry. “Simulated Tremor Propagation in the Upper Limb: From Muscle Activity to Joint Displacement.” 2018. Web. 20 Jan 2021.
Vancouver:
Corie TH. Simulated Tremor Propagation in the Upper Limb: From Muscle Activity to Joint Displacement. [Internet] [Masters thesis]. Brigham Young University; 2018. [cited 2021 Jan 20].
Available from: https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=7777&context=etd.
Council of Science Editors:
Corie TH. Simulated Tremor Propagation in the Upper Limb: From Muscle Activity to Joint Displacement. [Masters Thesis]. Brigham Young University; 2018. Available from: https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=7777&context=etd
3.
Pinto, Manuel Duarte Carvalho Lages.
Tremor essencial : visão global da doença.
Degree: 2013, Universidade da Beira Interior
URL: http://www.rcaap.pt/detail.jsp?id=oai:ubibliorum.ubi.pt:10400.6/1506
► O tremor essencial é uma das patologias mais comuns entre as patologias do sistema nervoso, sendo que é vista frequentemente pelos médicos neurologistas. Estima-se que…
(more)
▼ O tremor essencial é uma das patologias mais comuns entre as patologias do sistema nervoso,
sendo que é vista frequentemente pelos médicos neurologistas. Estima-se que a prevalência a
nível mundial desta doença se situe entre os 0,41% e os 3,92%.
Apesar de não haver uma causa definida para a doença, o que faz com que a sua etiologia
ainda permaneça, em grande parte, desconhecida dados recentes indicam-nos que a patologia
ocorre com um padrão familiar, embora se tenha verificado que também pode ocorrer de
forma esporádica. Foram identificados até ao momento pelo menos 3 genes que podem
aumentar a suscetibilidade para o tremor essencial: ETM1, ETM2 e ETM3. Existem também
evidências que alguns fatores de risco podem contribuir para o surgimento da patologia, entre
eles o álcool, o chumbo e os alcaloides do grupo das β-carbolinas. A evidência atual indicanos
que o tremor essencial é uma doença neurodegenerativa, em que há envolvimento
seletivo, tanto anatomicamente como fisiologicamente, de um sistema organizado de
neurónios, mais especificamente as células de Purkinje; para além disso, a patologia pode
eventualmente afetar sistemas não- motores, como por exemplo, a cognição e o olfato.
O tremor essencial é definido classicamente por um tremor de ação (postural ou cinético),
bilateral, em grande parte simétrico, que afeta mais frequentemente os braços e a cabeça e
que é visível e persistente. O diagnóstico diferencial é feito principalmente com a doença de
Parkinson.
As possibilidades terapêuticas para o tratamento do tremor essencial usadas hoje em dia
foram descobertas por tentativa-erro, sendo estas originalmente concebidos para outras
patologias. Os dois únicos fármacos com eficácia estabelecida para a patologia são o
Propranolol e a Primidona, sendo que a cirurgia está recomendada para casos mais graves e
refratários. Em estudo continuam futuras possibilidades terapêuticas.
Subjects/Keywords: Tremor essencial; Tremor essencial - Diagnóstico; Tremor essencial - Tratamento; Tremor essencial - Neuropatologia; Tremor essencial - Distúrbio do movimento
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Pinto, M. D. C. L. (2013). Tremor essencial : visão global da doença. (Thesis). Universidade da Beira Interior. Retrieved from http://www.rcaap.pt/detail.jsp?id=oai:ubibliorum.ubi.pt:10400.6/1506
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Pinto, Manuel Duarte Carvalho Lages. “Tremor essencial : visão global da doença.” 2013. Thesis, Universidade da Beira Interior. Accessed January 20, 2021.
http://www.rcaap.pt/detail.jsp?id=oai:ubibliorum.ubi.pt:10400.6/1506.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Pinto, Manuel Duarte Carvalho Lages. “Tremor essencial : visão global da doença.” 2013. Web. 20 Jan 2021.
Vancouver:
Pinto MDCL. Tremor essencial : visão global da doença. [Internet] [Thesis]. Universidade da Beira Interior; 2013. [cited 2021 Jan 20].
Available from: http://www.rcaap.pt/detail.jsp?id=oai:ubibliorum.ubi.pt:10400.6/1506.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Pinto MDCL. Tremor essencial : visão global da doença. [Thesis]. Universidade da Beira Interior; 2013. Available from: http://www.rcaap.pt/detail.jsp?id=oai:ubibliorum.ubi.pt:10400.6/1506
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Georgia Tech
4.
Kim, Jeonghee.
Assessment and modulation of essential tremor using peripheral-nerve stimulation.
Degree: PhD, Electrical and Computer Engineering, 2018, Georgia Tech
URL: http://hdl.handle.net/1853/61105
► Tremor is an abnormal oscillatory movement, observed in patients with essential tremor (ET), Parkinson’s Disease, and other neurological disorders. ET obstructs patient’s movements that require…
(more)
▼ Tremor is an abnormal oscillatory movement, observed in patients with essential
tremor (ET), Parkinson’s Disease, and other neurological disorders. ET obstructs patient’s movements that require high degrees of dexterity and precision, resulting in a reduction of the quality of life for the patient. Current quantification methods of ET, which typically rely on subjective ratings by trained clinicians or researchers, are potentially susceptible to inter- and intra-rater variability. Most treatments for reducing tremors, such as medications and thalamic deep brain stimulation, have not been adopted broadly because of the invasiveness of the treatments and their lack of efficacy. To address these limitations, the objectives of this PhD dissertation are (1) to quantitatively assess
tremor movement, and (2) to modulate/attenuate
tremor movement by adjusting the parameters of electrical stimulation on peripheral nerves using a custom-designed real-time system. I have developed (1) an automatic and quantitative method consisting of three computer-based tasks along with their performance metrics that assess the characteristics of
tremor, and (2) a wireless
tremor modulation system via peripheral-nerve electrical stimulation using a wearable wrist device. I analyzed that the performance metrics of the proposed computer-based assessment tasks were highly correlated with
tremor frequency and power. I found that peripheral-nerve stimulation significantly reduced the
tremor frequency and
tremor power, and the
subject with stronger
tremor exhibited a greater reduction in
tremor power. I examined the effects of the stimulation parameters (stimulation amplitude, frequency, duty cycle, phase, and stimulation sites), and found that the proper range of stimulation amplitudes varied according to current
tremor status. In a future study, I plan to develop a closed-loop optimization algorithm based on
tremor characteristics of each patient to maximize the effect of stimulation in
tremor modulation.
Advisors/Committee Members: DeWeerth, Stephen P. (advisor), Wichmann, Thomas (committee member), Butera, Robert J. (committee member), Grover, Martha A. (committee member), McKay, J. Lucas (committee member).
Subjects/Keywords: Essential tremor; Fitts’ law; Human motor performance; Kinetic tremor; Peripheral nerve electrical stimulation; Quantitative tremor assessment; Tremor modulation; Wearable tremor measurement
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Kim, J. (2018). Assessment and modulation of essential tremor using peripheral-nerve stimulation. (Doctoral Dissertation). Georgia Tech. Retrieved from http://hdl.handle.net/1853/61105
Chicago Manual of Style (16th Edition):
Kim, Jeonghee. “Assessment and modulation of essential tremor using peripheral-nerve stimulation.” 2018. Doctoral Dissertation, Georgia Tech. Accessed January 20, 2021.
http://hdl.handle.net/1853/61105.
MLA Handbook (7th Edition):
Kim, Jeonghee. “Assessment and modulation of essential tremor using peripheral-nerve stimulation.” 2018. Web. 20 Jan 2021.
Vancouver:
Kim J. Assessment and modulation of essential tremor using peripheral-nerve stimulation. [Internet] [Doctoral dissertation]. Georgia Tech; 2018. [cited 2021 Jan 20].
Available from: http://hdl.handle.net/1853/61105.
Council of Science Editors:
Kim J. Assessment and modulation of essential tremor using peripheral-nerve stimulation. [Doctoral Dissertation]. Georgia Tech; 2018. Available from: http://hdl.handle.net/1853/61105
5.
Paulo Henrique Garcia Mansur.
Análise de correlações entre tremor, degeneração celular e idade.
Degree: 2011, Federal University of Uberlândia
URL: http://www.bdtd.ufu.br//tde_busca/arquivo.php?codArquivo=3467
► O principal problema do tremor é o prejuízo causado à qualidade de vida do paciente, principalmente aqueles de idade mais avançada. Ainda não há um…
(more)
▼ O principal problema do tremor é o prejuízo causado à qualidade de vida do paciente, principalmente aqueles de idade mais avançada. Ainda não há um consenso sobre a origem desse distúrbio, mas ela pode ser investigada nas correlações entre os sinais biológicos do envelhecimento e as características do tremor. Este trabalho pesquisa a ocorrência de correlações entre a fragilidade osmótica de eritrócitos e as características dos sinais eletromiográficos do tremor em voluntários saudáveis (N = 44) de diferentes faixas etárias (24-87 anos). A fragilidade osmótica foi avaliada espectrofotometricamente pela dependência da hemólise, dada pela absorvância em 540 nm (A540), contra a concentração de NaCl. Os dados foram ajustados a curvas de regressão sigmoidal e caracterizados pelo ponto de meiatransição (H50), amplitude da transição de lise (dx) e valores de A540 nas regiões da curva onde os eritrócitos estão lisados (A1) ou íntegros (A2). A amplitude, freqüência e entropia aproximada do tremor foram avaliadas a partir dos sinais eletromiográficos adquiridos por eletrodos de superfície colocado no músculo extensor ulnar do carpo gerados por uma caneta laser colocada na mão de cada indivíduo em uma espiral de Arquimedes e também por dados coletados por um acelerômetro, posicionado na ponta da caneta. As avaliações foram feitas com a caneta laser em repouso no centro da espiral e em movimento do centro para fora e de fora para o centro. Foram testadas correlações entre os parâmetros da fragilidade osmótica, tremor, sexo e idade. Foram encontradas correlações negativas entre A1 e dx com a idade. Uma correlação positiva com H50 foi encontrada entre a entropia aproximada do tremor com a mão em repouso. Correlações negativas com H50 foram encontradas para a entropia do tremor com a mão em movimento tanto do centro para fora quanto de fora para o centro da espiral. Em indivíduos neurologicamente saudáveis, o aumento da fragilidade osmótica de eritrócitos foi associado a um aumento da entropia do tremor em repouso e a uma diminuição da entropia do tremor em movimento. Isso sugere que a degeneração neuromuscular associada ao tremor está vinculada ao mesmo mecanismo de ruptura da homeostase da membrana dos eritrócitos.
The main problem of tremor is the damage caused to the quality of the life of patients, especially those at more advanced ages. There is not a consensus yet about the origins of this disorder, but it can be examined in the correlations between the biological signs of aging and the tremor characteristics. This work sought correlations between the osmotic fragility of erythrocytes and features extracted from electromyographic (EMG) activity resulting from physiological tremor in healthy volunteers (N=44) at different age groups (24-87 years). The osmotic fragility was spectrophotometrically evaluated by the dependence of hemolysis, provided by the absorbance in 540 nm (A54o), on the concentration of NaCl. The data were adjusted to curves of sigmoidal regression and characterized by the half transition point (H50),…
Advisors/Committee Members: César Ferreira Amorim, Nilson Penha Silva, Sandra Maria Sbeghen Ferreira de Freitas, Adriano de Oliveira Andrade, Eduardo Lázaro Martins Naves.
Subjects/Keywords: Tremor; Envelhecimento; Fragilidade osmótica; ENGENHARIA ELETRICA; Tremor (Medicina); Idosos - Doenças; Tremor; Aging; Osmotic fragility; Electromyography
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APA (6th Edition):
Mansur, P. H. G. (2011). Análise de correlações entre tremor, degeneração celular e idade. (Thesis). Federal University of Uberlândia. Retrieved from http://www.bdtd.ufu.br//tde_busca/arquivo.php?codArquivo=3467
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Mansur, Paulo Henrique Garcia. “Análise de correlações entre tremor, degeneração celular e idade.” 2011. Thesis, Federal University of Uberlândia. Accessed January 20, 2021.
http://www.bdtd.ufu.br//tde_busca/arquivo.php?codArquivo=3467.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Mansur, Paulo Henrique Garcia. “Análise de correlações entre tremor, degeneração celular e idade.” 2011. Web. 20 Jan 2021.
Vancouver:
Mansur PHG. Análise de correlações entre tremor, degeneração celular e idade. [Internet] [Thesis]. Federal University of Uberlândia; 2011. [cited 2021 Jan 20].
Available from: http://www.bdtd.ufu.br//tde_busca/arquivo.php?codArquivo=3467.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Mansur PHG. Análise de correlações entre tremor, degeneração celular e idade. [Thesis]. Federal University of Uberlândia; 2011. Available from: http://www.bdtd.ufu.br//tde_busca/arquivo.php?codArquivo=3467
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Delft University of Technology
6.
Zheng, Jian (author).
Hand-tremor Frequency Estimation in Videos.
Degree: 2018, Delft University of Technology
URL: http://resolver.tudelft.nl/uuid:e32aabd8-6bd4-4dc5-bf82-0508702f67a3
► We focus on the problem of estimating human hand-tremor frequency from input RGB video data. Estimating tremors from video is important for non-invasive monitoring, analyzing…
(more)
▼ We focus on the problem of estimating human hand-tremor frequency from input RGB video data. Estimating tremors from video is important for non-invasive monitoring, analyzing and diagnosing patients suffering from motor-disorders such as Parkinson’s disease. We consider two approaches for hand-tremor frequency estimation: (a) a Lagrangian approach where we detect the hand at every frame in the video, and estimate the tremor frequency along the trajectory; and (b) an Eulerian approach where we first localize the hand, we subsequently remove the large motion along the movement trajectory of the hand, and we use the video information over time encoded as intensity values or phase information to estimate the tremor frequency. We estimate hand tremors on a new human tremor dataset, TIM-Tremor, containing 55 tremor patient recordings together with: associated ground truth accelerometer data from the most affected hand, RGB video data, and aligned depth data, as well as a multitude of more dynamic tasks, involving larger motion of the hands.
Embedded Systems
Advisors/Committee Members: van Gemert, Jan (mentor), Pintea, Silvia (mentor), Delft University of Technology (degree granting institution).
Subjects/Keywords: Video hand-tremor analysis; Phase-based tremor frequency detection; Human tremor datase; Eulerian hand tremors
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Zheng, J. (. (2018). Hand-tremor Frequency Estimation in Videos. (Masters Thesis). Delft University of Technology. Retrieved from http://resolver.tudelft.nl/uuid:e32aabd8-6bd4-4dc5-bf82-0508702f67a3
Chicago Manual of Style (16th Edition):
Zheng, Jian (author). “Hand-tremor Frequency Estimation in Videos.” 2018. Masters Thesis, Delft University of Technology. Accessed January 20, 2021.
http://resolver.tudelft.nl/uuid:e32aabd8-6bd4-4dc5-bf82-0508702f67a3.
MLA Handbook (7th Edition):
Zheng, Jian (author). “Hand-tremor Frequency Estimation in Videos.” 2018. Web. 20 Jan 2021.
Vancouver:
Zheng J(. Hand-tremor Frequency Estimation in Videos. [Internet] [Masters thesis]. Delft University of Technology; 2018. [cited 2021 Jan 20].
Available from: http://resolver.tudelft.nl/uuid:e32aabd8-6bd4-4dc5-bf82-0508702f67a3.
Council of Science Editors:
Zheng J(. Hand-tremor Frequency Estimation in Videos. [Masters Thesis]. Delft University of Technology; 2018. Available from: http://resolver.tudelft.nl/uuid:e32aabd8-6bd4-4dc5-bf82-0508702f67a3

Penn State University
7.
Yu, Ping.
Dynamics of Digit Tremor Within and Between Hands.
Degree: 2012, Penn State University
URL: https://submit-etda.libraries.psu.edu/catalog/13910
► Tremor is a very low amplitude involuntary oscillatory-like limb motion that is barely visible to the naked eye but present in all individuals. In this…
(more)
▼ Tremor is a very low amplitude involuntary oscillatory-like limb motion that is barely visible to the naked eye but present in all individuals. In this study, we investigated the
tremor dynamics of digits within and across hands that occurred under both 0 degree postural angle and 30 degree postural angle crossed with eyes open and eyes closed conditions. Twelve healthy young adults participated in the study (4 conditions, 12 trials/condition, 30s/trial) and accelerometers were used to measure digit
tremor. Amplitude analysis showed that the 30 degree posture angle increased the magnitude of acceleration regardless of vision condition. Visual information increased
tremor amplitude of the left hand but not the right hand digits.
Tremor amplitude was greater in the index finger and progressively smaller in the middle, ring and little fingers. Approximate Entropy (ApEn) showed that the higher postural angle led to greater
tremor irregularity. The coupling of the
tremor of the index and middle fingers was highest and the level of the coupling within hand decreased as the relative adjacency of digits from each other increased. There was no evidence of
tremor coupling in the homologous digits across hands. Postural angle of the digits and the availability of visual information modestly changed the scaling of the
tremor dynamics. It is concluded that the anatomical and physiological structures are the primary influence on the
tremor dynamics of amplitude and coupling within and between digits of the hands.
Advisors/Committee Members: Karl Maxim Newell, Thesis Advisor/Co-Advisor.
Subjects/Keywords: Digit tremor; Dynamics; Coherence
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Yu, P. (2012). Dynamics of Digit Tremor Within and Between Hands. (Thesis). Penn State University. Retrieved from https://submit-etda.libraries.psu.edu/catalog/13910
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Yu, Ping. “Dynamics of Digit Tremor Within and Between Hands.” 2012. Thesis, Penn State University. Accessed January 20, 2021.
https://submit-etda.libraries.psu.edu/catalog/13910.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Yu, Ping. “Dynamics of Digit Tremor Within and Between Hands.” 2012. Web. 20 Jan 2021.
Vancouver:
Yu P. Dynamics of Digit Tremor Within and Between Hands. [Internet] [Thesis]. Penn State University; 2012. [cited 2021 Jan 20].
Available from: https://submit-etda.libraries.psu.edu/catalog/13910.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Yu P. Dynamics of Digit Tremor Within and Between Hands. [Thesis]. Penn State University; 2012. Available from: https://submit-etda.libraries.psu.edu/catalog/13910
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Victoria University of Wellington
8.
Boese, Carolin.
Microseismicity in the central Southern Alps, Westland, New Zealand.
Degree: 2012, Victoria University of Wellington
URL: http://hdl.handle.net/10063/3639
► Present-day seismicity associated with the central Alpine Fault and the zone of active deformation and rock uplift in the central Southern Alps is reported in…
(more)
▼ Present-day seismicity associated with the central Alpine Fault and the zone of active deformation and rock uplift in the central Southern Alps is reported in this thesis. Robust hypocentre locations and magnitude estimates for ~2300 earthquakes have been obtained analysing 18 months of data from the Southern Alps Microearthquake Borehole Array (SAMBA), designed for this study. The earthquakes are distributed between the Alpine Fault and the Main Divide Fault zone and confined to shallow depths (90% of events ≤12.2 km). The thickness of the seismogenic zone follows lateral variations in crustal resistivity: earthquake hypocentres are restricted to depths where resistivities exceed 390 Ω m. Rocks at greater depth are interpreted to be too hot, too fluid-saturated, or too weak to produce detectable earthquakes. A low-seismicity zone extends between the Whataroa and Wanganui rivers at distances 15–30 km southeast of the fault, which is concluded to be a relatively strong, unfractured block that diverts deformation around it. A new magnitude scale is developed incorporating the effects of frequency-dependent attenuation, which enables magnitudes to be calculated consistently for earthquakes of different sizes and frequency contents. Focal mechanism solutions for 379 earthquakes exhibit predominantly strike-slip mechanisms. Inversion of these focal mechanisms to determine the prevailing tectonic stress field reveals a maximum horizontal compressive stress direction of 115±10°, consistent with findings from elsewhere in South Island. The 60° angle between the strike of the Alpine Fault and the direction of maximum horizontal compressive stress suggests that the Alpine Fault is poorly oriented in an Andersonian sense. Earthquake swarms of at least 10 events with similar waveforms frequently occur within the region, of which some were remotely triggered by two major South Island earthquakes. Focal mechanisms of the largest event in each swarm (ML≤2.8) reveal at least one steeply-dipping nodal plane (≥50°) and one well-oriented nodal plane in the tectonic stress field. The swarms exhibit a distinctly different inter-event time versus duration pattern from that of typical mainshock-aftershock sequences. The triggered seismicity commences with the passage of the surface waves, continues for ~5 and ~2 days, and is followed by a quiescence period of approximately equal length. Remotely triggered swarms occur delayed by several hours and their delay and locations are consistent with fluid diffusion from a shallow fluid reservoir. Estimated peak dynamic stresses (≥0.09 MPa) imposed by the surface waves are comparable to observations of triggering thresholds (>0.01 MPa) elsewhere. The triggered swarms have no apparent differences from the background swarms, and appear to have been clock-advanced. Tectonic
tremor in the vicinity of the Alpine Fault coincides with a low-velocity, high-attenuation zone at depth. The
tremor occurs at the downdip extension of the Alpine Fault and in the region where bending of the Australian and Pacific…
Advisors/Committee Members: Stern, Tim, Smith, Euan, Townend, John.
Subjects/Keywords: Tremor; Triggered swarms; Microseismicity
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MLA ·
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APA (6th Edition):
Boese, C. (2012). Microseismicity in the central Southern Alps, Westland, New Zealand. (Doctoral Dissertation). Victoria University of Wellington. Retrieved from http://hdl.handle.net/10063/3639
Chicago Manual of Style (16th Edition):
Boese, Carolin. “Microseismicity in the central Southern Alps, Westland, New Zealand.” 2012. Doctoral Dissertation, Victoria University of Wellington. Accessed January 20, 2021.
http://hdl.handle.net/10063/3639.
MLA Handbook (7th Edition):
Boese, Carolin. “Microseismicity in the central Southern Alps, Westland, New Zealand.” 2012. Web. 20 Jan 2021.
Vancouver:
Boese C. Microseismicity in the central Southern Alps, Westland, New Zealand. [Internet] [Doctoral dissertation]. Victoria University of Wellington; 2012. [cited 2021 Jan 20].
Available from: http://hdl.handle.net/10063/3639.
Council of Science Editors:
Boese C. Microseismicity in the central Southern Alps, Westland, New Zealand. [Doctoral Dissertation]. Victoria University of Wellington; 2012. Available from: http://hdl.handle.net/10063/3639

University of Florida
9.
Lafo, Jacob A.
Emotion Perception and Reactivity in Essential Tremor.
Degree: PhD, Psychology - Clinical and Health Psychology, 2018, University of Florida
URL: https://ufdc.ufl.edu/UFE0052648
► Essential tremor (ET) is a highly prevalent movement disorder characterized by action tremor. Tremor development has been linked with degenerative changes in the cerebellum, a…
(more)
▼ Essential
tremor (ET) is a highly prevalent movement disorder characterized by action
tremor.
Tremor development has been linked with degenerative changes in the cerebellum, a brain structure traditionally associated with motor control and integration. Essential
tremor is also associated with mild cognitive symptoms, which have been attributed to alterations in cerebellar-cortical circuitry. In light of neuroanatomical evidence of cerebellar-limbic connectivity and recent observations in our laboratory of emotional blunting in ET, the question arises as to whether emotion-specific circuitry may also be affected in ET, secondary to cerebellar pathology.
Advisors/Committee Members: BOWERS,DAWN (committee chair), FEDELE,DAVID ANDREW (committee member), BRADLEY,MARGARET M (committee member).
Subjects/Keywords: cerebellum – emotion – essential – startle – tremor
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APA ·
Chicago ·
MLA ·
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Export
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APA (6th Edition):
Lafo, J. A. (2018). Emotion Perception and Reactivity in Essential Tremor. (Doctoral Dissertation). University of Florida. Retrieved from https://ufdc.ufl.edu/UFE0052648
Chicago Manual of Style (16th Edition):
Lafo, Jacob A. “Emotion Perception and Reactivity in Essential Tremor.” 2018. Doctoral Dissertation, University of Florida. Accessed January 20, 2021.
https://ufdc.ufl.edu/UFE0052648.
MLA Handbook (7th Edition):
Lafo, Jacob A. “Emotion Perception and Reactivity in Essential Tremor.” 2018. Web. 20 Jan 2021.
Vancouver:
Lafo JA. Emotion Perception and Reactivity in Essential Tremor. [Internet] [Doctoral dissertation]. University of Florida; 2018. [cited 2021 Jan 20].
Available from: https://ufdc.ufl.edu/UFE0052648.
Council of Science Editors:
Lafo JA. Emotion Perception and Reactivity in Essential Tremor. [Doctoral Dissertation]. University of Florida; 2018. Available from: https://ufdc.ufl.edu/UFE0052648

RMIT University
10.
Tan, A.
Analysis of physiological tremor mechanisms in surface electromyogram.
Degree: 2013, RMIT University
URL: http://researchbank.rmit.edu.au/view/rmit:160598
► Rhythmical grouping of action potential in the low frequency band have been observed during steady, constant force contractions. The origins of this rhythmical pattern have…
(more)
▼ Rhythmical grouping of action potential in the low frequency band have been observed during steady, constant force contractions. The origins of this rhythmical pattern have always been associated to tremor oscillations. However, literature concerning physiological tremor has shown that the origin of tremor remains inconclusive with various works providing valid arguments and counter-arguments for the various mechanisms proposed. Physiological tremor oscillation has consistently been associated with the following four mechanisms: a) synchronisation of motor units; b) mechanical feedback resonance; c) feedback resonance from neural delay and d) central oscillations. It is largely believed that the overall tremor oscillation is either the interaction effect of various oscillatory mechanisms acting in parallel with each other or one or other mechanisms acting predominantly in various situations. The objective of this research was to determine the role of neural feedback and muscle mechanics in the generation of physiological tremor oscillation. This research developed a neuromuscular model to simulate the individual and resulting oscillatory mechanisms of tremor. The oscillations found in EMG signal were also analysed empirically from EMG data from 54 subjects using Hilbert Transform and rectification to obtain the envelope of the signal. The time between rhythmical waveform patterns in the EMG signal, TC was found to be 78ms. This value corresponded to the supraspinal neural delay, 50-80ms reported in literature and the theoretical value of the supraspinal feedback simulated from the model. The theoretical model also reported a predominant mechanical resonance frequency in the resulting oscillation between muscle and spinal feedback and the resulting oscillation between muscle, spinal and supraspinal feedback. These observations coincide with the physiological tremor oscillations reported in literature: the mechanical-reflex and the 8-12Hz. The mechanical-reflex oscillation is defined to be the product of spinal feedback and muscle mechanics and is found to be highly influenced by the mechanical properties of muscle. The 8-12Hz component is reported to originate from the interaction of supraspinal and central mechanisms. TC has shown to coincide with the supraspinal neural delay time and the theoretical supraspinal value suggesting that TC correlates to the 8-12Hz component.
Subjects/Keywords: Fields of Research; EMG; Physiological Tremor; Neuromuscular modelling; Tremor Oscillation
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
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APA (6th Edition):
Tan, A. (2013). Analysis of physiological tremor mechanisms in surface electromyogram. (Thesis). RMIT University. Retrieved from http://researchbank.rmit.edu.au/view/rmit:160598
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Tan, A. “Analysis of physiological tremor mechanisms in surface electromyogram.” 2013. Thesis, RMIT University. Accessed January 20, 2021.
http://researchbank.rmit.edu.au/view/rmit:160598.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Tan, A. “Analysis of physiological tremor mechanisms in surface electromyogram.” 2013. Web. 20 Jan 2021.
Vancouver:
Tan A. Analysis of physiological tremor mechanisms in surface electromyogram. [Internet] [Thesis]. RMIT University; 2013. [cited 2021 Jan 20].
Available from: http://researchbank.rmit.edu.au/view/rmit:160598.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Tan A. Analysis of physiological tremor mechanisms in surface electromyogram. [Thesis]. RMIT University; 2013. Available from: http://researchbank.rmit.edu.au/view/rmit:160598
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Brigham Young University
11.
Standring, David Jordan.
Distribution of Tremorogenic Activity among the MajorSuperficial Muscles of the Upper Limb inSubjects with Essential Tremor.
Degree: MS, 2019, Brigham Young University
URL: https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=8557&context=etd
► Optimized peripheral tremor suppression could address many limitations of surgical or medicinal treatments of Essential Tremor, however it is not well understood how the…
(more)
▼ Optimized peripheral tremor suppression could address many limitations of surgical or medicinal treatments of Essential Tremor, however it is not well understood how the tremorogenic activity is distributed among the muscles of the upper limb, and therefore how to optimize such suppression. We recorded electromyographic (EMG) activity in the 15 major superficial muscles from the shoulder to the wrist while subjects performed postural and kinetic tasks similar to activities of daily living. We calculated the power spectral density and computed the total power in the tremor band (4"12 Hz) for each muscle, from which we determined the distribution of tremorogenic activity among the 15 muscles for various conditions. Differences in distribution between conditions were quantified as Pearson correlation coefficients. All 15 muscles exhibited some tremorogenic activity. The anterior deltoid exhibited by far the most power, the wrist extensors had more power than other distal muscles, and the triceps longus showed the least power. Distributions among muscles was highly consistent across repetitions (r = 0.91 ± 0.07) and somewhat stereotyped across subjects (r = 0.58 ± 0.31). Differences in task (postural vs. kinetic), limb configuration, and subject characteristics (sex; tremor severity, onset, and duration) had little effect on distribution (r =0.84). Interestingly, the distribution of tremorogenic activity was highly correlated (r = 0.94 ± 0.08) with the distribution of voluntary activity (power between 0.5 and 4 Hz). In particular, muscles opposing gravity had the highest amount of tremorogenic activity. This may explain in part why the distribution of tremorogenic activity was stereotyped across subjects.
Subjects/Keywords: essential tremor; EMG; tremor distribution; upper limb; PSD
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Standring, D. J. (2019). Distribution of Tremorogenic Activity among the MajorSuperficial Muscles of the Upper Limb inSubjects with Essential Tremor. (Masters Thesis). Brigham Young University. Retrieved from https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=8557&context=etd
Chicago Manual of Style (16th Edition):
Standring, David Jordan. “Distribution of Tremorogenic Activity among the MajorSuperficial Muscles of the Upper Limb inSubjects with Essential Tremor.” 2019. Masters Thesis, Brigham Young University. Accessed January 20, 2021.
https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=8557&context=etd.
MLA Handbook (7th Edition):
Standring, David Jordan. “Distribution of Tremorogenic Activity among the MajorSuperficial Muscles of the Upper Limb inSubjects with Essential Tremor.” 2019. Web. 20 Jan 2021.
Vancouver:
Standring DJ. Distribution of Tremorogenic Activity among the MajorSuperficial Muscles of the Upper Limb inSubjects with Essential Tremor. [Internet] [Masters thesis]. Brigham Young University; 2019. [cited 2021 Jan 20].
Available from: https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=8557&context=etd.
Council of Science Editors:
Standring DJ. Distribution of Tremorogenic Activity among the MajorSuperficial Muscles of the Upper Limb inSubjects with Essential Tremor. [Masters Thesis]. Brigham Young University; 2019. Available from: https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=8557&context=etd

Brigham Young University
12.
Davidson, Andrew Doran.
Fundamental Principles of Tremor Propagation in the Upper Limb.
Degree: MS, 2016, Brigham Young University
URL: https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=7509&context=etd
► Although tremor is the most common movement disorder, there exist few effective tremor-suppressing devices, in part because the characteristics of tremor throughout the upper limb…
(more)
▼ Although tremor is the most common movement disorder, there exist few effective tremor-suppressing devices, in part because the characteristics of tremor throughout the upper limb are unknown. To clarify, optimally suppressing tremor requires a knowledge of the mechanical origin, propagation, and distribution of tremor throughout the upper limb. Here we present the first systematic investigation of how tremor propagates between the shoulder, elbow, forearm, and wrist. We simulated tremor propagation using a linear, time-invariant, lumped-parameter musculoskeletal model relating joint torques and the resulting joint displacements. The model focused on the seven main degrees of freedom (DOF) from the shoulder to the wrist and included coupled joint inertia, damping, and stiffness. We deliberately implemented a simple model to focus first on the most basic effects. Simulating tremorogenic joint torque as a sinusoidal input, we used the model to establish fundamental principles describing how input parameters (torque location and frequency) and joint impedance (inertia, damping, and stiffness) affect tremor propagation. We expect that the methods and principles presented here will serve as the groundwork for future refining studies to understand the origin, propagation, and distribution of tremor throughout the upper limb in order to enable the future development of optimal tremor-suppressing devices.
Subjects/Keywords: Essential Tremor; Parkinson's Disease; musculoskeletal dynamics; tremor suppression; Mechanical Engineering
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Davidson, A. D. (2016). Fundamental Principles of Tremor Propagation in the Upper Limb. (Masters Thesis). Brigham Young University. Retrieved from https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=7509&context=etd
Chicago Manual of Style (16th Edition):
Davidson, Andrew Doran. “Fundamental Principles of Tremor Propagation in the Upper Limb.” 2016. Masters Thesis, Brigham Young University. Accessed January 20, 2021.
https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=7509&context=etd.
MLA Handbook (7th Edition):
Davidson, Andrew Doran. “Fundamental Principles of Tremor Propagation in the Upper Limb.” 2016. Web. 20 Jan 2021.
Vancouver:
Davidson AD. Fundamental Principles of Tremor Propagation in the Upper Limb. [Internet] [Masters thesis]. Brigham Young University; 2016. [cited 2021 Jan 20].
Available from: https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=7509&context=etd.
Council of Science Editors:
Davidson AD. Fundamental Principles of Tremor Propagation in the Upper Limb. [Masters Thesis]. Brigham Young University; 2016. Available from: https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=7509&context=etd
13.
Maria Fernanda Soares de Almeida.
Análise temporal da relação entre o tremor fisiológico cinético e o envelhecimento com base em desenhos digitalizados da espiral de Arquimedes.
Degree: 2011, Federal University of Uberlândia
URL: http://www.bdtd.ufu.br//tde_busca/arquivo.php?codArquivo=3888
► Tremor is the most common movement disorder characterized by repetitive and stereotyped movements, and the elderly is the most affected population. The movement caused by…
(more)
▼ Tremor is the most common movement disorder characterized by repetitive and stereotyped movements, and the elderly is the most affected population. The movement caused by tremor can be associated to many factors such as neurological disorders and natural processes. The latter is often referred to as physiological tremor and is present in greater or lesser degree, in all humans. The presence of severe tremor disorders causes many difficulties, and can indicate even the presence of diseases related to central nervous system. However, the dividing landmark between physiological tremor and that resultant of dysfunctions is tenuous and has not been precisely established. Thousands of people each year, begin to present some type of motor dysfunction, which interferes in their daily activities and reduces significantly the quality of life of these individuals. Most investigations on tremor attempt to understand its relation to neuromuscular dysfunctions. Therefore, there is a lack of studies that aim to investigate the complex relation between the physiological tremor and ageing, especially in kinetic conditions. In this context, the main motivation of this research was to quantify and analyse age-related changes in the kinetic tremor of clinically healthy individuals. For this, a number of features extracted from tremor activity, obtained from digitized drawings of Archimedes spirals, were analysed. In total, 59 subjects participated in the experiments. These individuals were divided into seven groups according to their ages and three types of analysis were carried out. First, the tremor activity was investigated by means of traditional features commonly used in tremor analysis, and secondly, Linear Discriminant Analysis (LDA) was employed for the study of the correlation between age and tremor. Finally, experimental nonlinear time series features were employed, such as state space reconstruction and estimation of Lyapunov exponents. The results obtained through the LDA showed significant statistical differences between the kinetic tremor activity of the young and elderly groups. Furthermore, it was found that LDA allowed for the estimate of a unique feature, so-called LDA-value, which showed to be linearly correlated with age.
O tremor humano é o distúrbio mais comum do movimento caracterizado por movimentos repetitivos e esteriotipados, sendo os idosos a população mais afetada. O movimento causado pelo tremor pode estar associado a diversos fatores, tais como disfunções neurológicas ou, até mesmo, a processos naturais. Neste último caso, diz-se que o tremor é fisiológico e está presente, em maior ou menor intensidade, em todos os seres humanos. A presença acentuada do tremor causa diversos transtornos e dificuldades, podendo indicar, inclusive, a presença de doenças ligadas ao sistema nervoso central. Entretanto, o marco divisório entre o tremor fisiológico e o resultante de disfunções é tênue e ainda não foi precisamente estabelecido. Milhares de pessoas, todos os anos, passam a apresentar algum tipo de disfunção…
Advisors/Committee Members: Adriano Alves Pereira, Adriano de Oliveira Andrade, Sheila Bernardino Fenelon, César Ferreira Amorim, Paulo César Cortez.
Subjects/Keywords: Tremor cinético; Tremor fisiológico; Envelhecimento; Espiral de arquimedes; Mesa digitalizadora; ENGENHARIA ELETRICA; Tremor (Medicina); Kinetic tremor; Physiological tremor; Ageing; Archimedes spiral; Digitizing tablet
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APA ·
Chicago ·
MLA ·
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CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Almeida, M. F. S. d. (2011). Análise temporal da relação entre o tremor fisiológico cinético e o envelhecimento com base em desenhos digitalizados da espiral de Arquimedes. (Thesis). Federal University of Uberlândia. Retrieved from http://www.bdtd.ufu.br//tde_busca/arquivo.php?codArquivo=3888
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Almeida, Maria Fernanda Soares de. “Análise temporal da relação entre o tremor fisiológico cinético e o envelhecimento com base em desenhos digitalizados da espiral de Arquimedes.” 2011. Thesis, Federal University of Uberlândia. Accessed January 20, 2021.
http://www.bdtd.ufu.br//tde_busca/arquivo.php?codArquivo=3888.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Almeida, Maria Fernanda Soares de. “Análise temporal da relação entre o tremor fisiológico cinético e o envelhecimento com base em desenhos digitalizados da espiral de Arquimedes.” 2011. Web. 20 Jan 2021.
Vancouver:
Almeida MFSd. Análise temporal da relação entre o tremor fisiológico cinético e o envelhecimento com base em desenhos digitalizados da espiral de Arquimedes. [Internet] [Thesis]. Federal University of Uberlândia; 2011. [cited 2021 Jan 20].
Available from: http://www.bdtd.ufu.br//tde_busca/arquivo.php?codArquivo=3888.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Almeida MFSd. Análise temporal da relação entre o tremor fisiológico cinético e o envelhecimento com base em desenhos digitalizados da espiral de Arquimedes. [Thesis]. Federal University of Uberlândia; 2011. Available from: http://www.bdtd.ufu.br//tde_busca/arquivo.php?codArquivo=3888
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Texas A&M University
14.
Higby, Kevin Kenneth.
The Effect of Fluid Flow in Fault Gouge During Simulated Earthquakes.
Degree: MS, Geophysics, 2016, Texas A&M University
URL: http://hdl.handle.net/1969.1/156952
► When the frictional strength of a fault zone is met, displacement occurs within the fault zone. Displacement can occur at a seismogenic or aseismic velocity.…
(more)
▼ When the frictional strength of a fault zone is met, displacement occurs within the fault zone. Displacement can occur at a seismogenic or aseismic velocity. Seismogenic events cause devastating earthquakes while aseismic activity is the result of low velocity slip events. These slow slip events are thought to be from over pressured pore pressures present in the fault zone.
This work investigates the effect of pore fluid flow within fault gouge during an earthquake by using a grain scale numerical model. Fault gouge is simulated using a Discrete Element Model (DEM) that is coupled with grain motion to generate pressures from fluid flow. We compare the evolution of an earthquake using numerical simulations that began with identical granular arrangements run with a high permeability (drained) and a low permeability (undrained). Drained simulations are defined as those where fluid can flow freely enough such that the slip event is not affected by it. Undrained simulations are those in which pore fluid pressure cannot flow, and the strength of the system is severely affected by pressure perturbations.
Type I events the undrained system reached a lower static strength while Type II events are those where the undrained system achieved a higher static strength. Local granular rearrangements are responsible for the strengthening or weakening of the undrained events.
The slip velocities during a simulated earthquake in a drained system are well modeled by the block slider model with a constant coefficient of dynamic friction. However, a number of undrained earthquakes showed complex slip characteristics including abrupt changes in velocity and a variable dynamic resistance. These slip events resemble creep-like and
tremor-like behavior seen in natural subduction zones and caused by pressure perturbations within the gouge zone.
We find fluid pressure perturbations can weaken the static strength of undrained systems, but not always. This shows reductions in pressures play the dominant role in controlling the strength of a system. In addition, the dynamic resistance of complex events is primarily controlled by fluid flow, and not a variable coefficient of dynamic friction.
Advisors/Committee Members: Sparks, David W (advisor), Duan, Benchun (committee member), Sanchez, Marcelo (committee member).
Subjects/Keywords: fluid flow; numerical simulations; fault gouge; creep; tremor; earthquake creep; earthquake tremor; fluid tremor; fluid creep
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Higby, K. K. (2016). The Effect of Fluid Flow in Fault Gouge During Simulated Earthquakes. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/156952
Chicago Manual of Style (16th Edition):
Higby, Kevin Kenneth. “The Effect of Fluid Flow in Fault Gouge During Simulated Earthquakes.” 2016. Masters Thesis, Texas A&M University. Accessed January 20, 2021.
http://hdl.handle.net/1969.1/156952.
MLA Handbook (7th Edition):
Higby, Kevin Kenneth. “The Effect of Fluid Flow in Fault Gouge During Simulated Earthquakes.” 2016. Web. 20 Jan 2021.
Vancouver:
Higby KK. The Effect of Fluid Flow in Fault Gouge During Simulated Earthquakes. [Internet] [Masters thesis]. Texas A&M University; 2016. [cited 2021 Jan 20].
Available from: http://hdl.handle.net/1969.1/156952.
Council of Science Editors:
Higby KK. The Effect of Fluid Flow in Fault Gouge During Simulated Earthquakes. [Masters Thesis]. Texas A&M University; 2016. Available from: http://hdl.handle.net/1969.1/156952

Brigham Young University
15.
Pigg, Adam Charles.
Distribution of Essential Tremor in the Degrees of Freedom of the Upper Limb.
Degree: MS, 2017, Brigham Young University
URL: https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=8212&context=etd
► This study seeks to understand upper limb tremor in subjects with essential tremor (ET). A thorough understanding of tremor distribution will allow for the more…
(more)
▼ This study seeks to understand upper limb tremor in subjects with essential tremor (ET). A thorough understanding of tremor distribution will allow for the more effective development of tremor suppression devices, which offer an alternative to current treatments. Previous studies primarily focused on tremor in the hand only. This study seeks to characterize the distribution of tremor throughout the upper limb.We measured tremor in 25 subjects diagnosed with ET using motion capture, which provided displacement information of the limb during multiple postural and kinetic tasks. Inverse kinematics allowed us to analyze the motion capture data in the 7 major degrees of freedom (DOF) of the upper limb. The power spectral density estimate was used to determine: relative tremor magnitude throughout the DOFs, tremor variation between tasks, variation between subjects, and frequency variations between DOFs. Data analysis revealed that tremor increase is roughly proximal to distal. We also show that tremor magnitude in kinetic tasks is significantly higher than in postural tasks. Although we found some variation in tremor distribution between subjects, the roughly proximal to distal increase in tremor severity holds for several subsets of the study population. Finally, we found that tremor frequency doesn<&apos>t vary significantly (< 1 Hz) between DOFs, in subjects with severe tremor. Our study shows that tremor distribution is quite stereotyped between subjects with ET. Furthermore, we have shown that tremor is greatest in the distal DOFs. This provides a compelling starting point for the development of future tremor suppression devices.
Subjects/Keywords: essential tremor; motion capture; inverse kinematics; power spectral density; tremor characterization; tremor distribution; upper limb; degrees of freedom
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Pigg, A. C. (2017). Distribution of Essential Tremor in the Degrees of Freedom of the Upper Limb. (Masters Thesis). Brigham Young University. Retrieved from https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=8212&context=etd
Chicago Manual of Style (16th Edition):
Pigg, Adam Charles. “Distribution of Essential Tremor in the Degrees of Freedom of the Upper Limb.” 2017. Masters Thesis, Brigham Young University. Accessed January 20, 2021.
https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=8212&context=etd.
MLA Handbook (7th Edition):
Pigg, Adam Charles. “Distribution of Essential Tremor in the Degrees of Freedom of the Upper Limb.” 2017. Web. 20 Jan 2021.
Vancouver:
Pigg AC. Distribution of Essential Tremor in the Degrees of Freedom of the Upper Limb. [Internet] [Masters thesis]. Brigham Young University; 2017. [cited 2021 Jan 20].
Available from: https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=8212&context=etd.
Council of Science Editors:
Pigg AC. Distribution of Essential Tremor in the Degrees of Freedom of the Upper Limb. [Masters Thesis]. Brigham Young University; 2017. Available from: https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=8212&context=etd

University of Connecticut
16.
Podurgiel, Samantha J.
Tremulous Jaw Movements Induced by the VMAT2 Inhibitor Tetrabenazine.
Degree: MA, Psychology, 2012, University of Connecticut
URL: https://opencommons.uconn.edu/gs_theses/359
► Parkinsonism is a movement disorder characterized by several cardinal motor symptoms: resting tremor, akinesia, bradykinesia, rigidity, and postural instability. Parkinsonian resting tremor can be…
(more)
▼ Parkinsonism is a movement disorder characterized by several cardinal motor symptoms: resting
tremor, akinesia, bradykinesia, rigidity, and postural instability. Parkinsonian resting
tremor can be modeled in rodents using the tremulous jaw movement model. Tremulous jaw movements (TJMs) are defined as “rapid vertical deflections of the lower jaw that resemble chewing but are not directed at any particular stimulus.” TJMs occur in a frequency range of 3-7 Hz and are induced by a number of pharmacological manipulations that parallel those seen in human Parkinsonism including dopamine (DA) depleting agents, DA antagonists, and cholinomimetic administration. Additionally, TJMs can be attenuated using antiparkinsonian agents including L-DOPA, DA agonists, anticholinergics, and adenosine A
2A antagonists. Tetrabenazine (TBZ) is a reversible VMAT2 inhibitor that is approved by the FDA for treatment of chorea associated with Huntington’s disease (HD). While TBZ inhibits storage of all monoamines into synaptic vesicles it has been shown to preferentially target DA. Therefore, patients being treated with TBZ often experience depression and Parkinsonism as side effects. The present studies demonstrate the ability of TBZ to induce Parkinsonian
tremor using the tremulous jaw movement model. When administered to rats, tetrabenazine (0.25, 0.5, 1.0, 2.0 mg/kg IP) significantly induces tremulous jaw movements in a dose-dependent manner. Freeze frame video analysis reveals these TJMs primarily occur in the 3.0-7.5 Hz frequency range, which falls in the frequency range characteristic of parkinsonian resting
tremor. Coadministration of the adenosine A
2A antagonist MSX-3 (1.25, 2.5, 5.0, 10.0 mg/kg IP) significantly attenuates TJMs induced by 2.0 mg/kg TBZ in rats. Similarly, coadministration of MSX-3 (2.5, 5.0, 10.0 mg/kg IP) significantly reduces the number of TJMs induced by 10.0 mg/kg TBZ in mice. To provide a cellular marker of these pharmacological conditions, we examined c-Fos expression in the ventrolateral neostriatum (VLS), the region of the brain most closely associated with the production of TJMs. 2.0 mg/kg TBZ significantly increased the number of c-Fos positive cells in the VLS, while coadministration of 10.0 mg/kg MSX-3 significantly reduced the number of c-Fos positive cells. Taken together, the results indicate that TBZ induces
tremor as measured in the tremulous jaw movement model. MSX-3 is capable of attenuating this behavior by blunting the cellular effects caused by TBZ administration, thus lending further support to the use of adenosine A
2A antagonists as antiparkinsonian agents.
Advisors/Committee Members: Merce Correa, James Chrobak, John Salamone.
Subjects/Keywords: tetrabenazine; Parkinson's disease; dopamine; knockout; tremor
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Chicago ·
MLA ·
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APA (6th Edition):
Podurgiel, S. J. (2012). Tremulous Jaw Movements Induced by the VMAT2 Inhibitor Tetrabenazine. (Masters Thesis). University of Connecticut. Retrieved from https://opencommons.uconn.edu/gs_theses/359
Chicago Manual of Style (16th Edition):
Podurgiel, Samantha J. “Tremulous Jaw Movements Induced by the VMAT2 Inhibitor Tetrabenazine.” 2012. Masters Thesis, University of Connecticut. Accessed January 20, 2021.
https://opencommons.uconn.edu/gs_theses/359.
MLA Handbook (7th Edition):
Podurgiel, Samantha J. “Tremulous Jaw Movements Induced by the VMAT2 Inhibitor Tetrabenazine.” 2012. Web. 20 Jan 2021.
Vancouver:
Podurgiel SJ. Tremulous Jaw Movements Induced by the VMAT2 Inhibitor Tetrabenazine. [Internet] [Masters thesis]. University of Connecticut; 2012. [cited 2021 Jan 20].
Available from: https://opencommons.uconn.edu/gs_theses/359.
Council of Science Editors:
Podurgiel SJ. Tremulous Jaw Movements Induced by the VMAT2 Inhibitor Tetrabenazine. [Masters Thesis]. University of Connecticut; 2012. Available from: https://opencommons.uconn.edu/gs_theses/359

University of Miami
17.
Sargolzaei, Saman.
Impact of Accelerometry and Spirography Data Analysis of Essential Tremor on BOLD-fMRI Data Interpretation.
Degree: MS, Electrical and Computer Engineering (Engineering), 2012, University of Miami
URL: https://scholarlyrepository.miami.edu/oa_theses/309
► Essential Tremor (ET) is the most common neurological movement disorder, with slowly progressive symptoms that impact the patient's quality of life and ability to perform…
(more)
▼ Essential
Tremor (ET) is the most common neurological movement disorder, with slowly progressive symptoms that impact the patient's quality of life and ability to perform activities of daily living. Tremors in ET occur during kinetic, with two subtypes: postural tremors and kinetic tremors. Postural tremors appear when the arms are topically maintained in a position against gravity, whereas kinetic tremors appear during sustained voluntary movements such as writing or drawing. The underlying mechanisms of either
tremor type are not known, and further work is needed to determine whether they are two manifestations of the same brain dysfunction, or consequences of different underlying causes. To further understand these disease manifestations, we employed functional magnetic resonance imaging (fMRI) in conjunction with quantitative
tremor measures (accelerometry and spirography).
Advisors/Committee Members: Mohamed Abdel-Mottaleb, Fatta Basil Nahab, Saman Aliari Zonouz.
Subjects/Keywords: Accelerometry; Essential Tremor; Functional MRI; Spirography
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APA ·
Chicago ·
MLA ·
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CSE |
Export
to Zotero / EndNote / Reference
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APA (6th Edition):
Sargolzaei, S. (2012). Impact of Accelerometry and Spirography Data Analysis of Essential Tremor on BOLD-fMRI Data Interpretation. (Thesis). University of Miami. Retrieved from https://scholarlyrepository.miami.edu/oa_theses/309
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Sargolzaei, Saman. “Impact of Accelerometry and Spirography Data Analysis of Essential Tremor on BOLD-fMRI Data Interpretation.” 2012. Thesis, University of Miami. Accessed January 20, 2021.
https://scholarlyrepository.miami.edu/oa_theses/309.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Sargolzaei, Saman. “Impact of Accelerometry and Spirography Data Analysis of Essential Tremor on BOLD-fMRI Data Interpretation.” 2012. Web. 20 Jan 2021.
Vancouver:
Sargolzaei S. Impact of Accelerometry and Spirography Data Analysis of Essential Tremor on BOLD-fMRI Data Interpretation. [Internet] [Thesis]. University of Miami; 2012. [cited 2021 Jan 20].
Available from: https://scholarlyrepository.miami.edu/oa_theses/309.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Sargolzaei S. Impact of Accelerometry and Spirography Data Analysis of Essential Tremor on BOLD-fMRI Data Interpretation. [Thesis]. University of Miami; 2012. Available from: https://scholarlyrepository.miami.edu/oa_theses/309
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Texas Southwestern Medical Center
18.
Dhima, Kaltra.
A Data-Driven Approach for Deriving Parkinson’s Disease Subtypes and Related Trajectories of Cognitive and Motor Function.
Degree: 2018, University of Texas Southwestern Medical Center
URL: http://hdl.handle.net/2152.5/8806
► Parkinson's disease (PD) is a progressive neurological illness that involves a variety of motor and non-motor features, with remarkable heterogeneity in clinical presentation and symptom…
(more)
▼ Parkinson's disease (PD) is a progressive neurological illness that involves a variety of motor and non-motor features, with remarkable heterogeneity in clinical presentation and symptom progression. Previous studies have attempted to identify PD subtypes to better understand the clinical implications of this heterogeneity, though reliable subtypes remain unclear due to inconsistencies across studies, non-generalizable samples, and low subtype stability over time. This study aimed to identify PD subtypes based on motor, cognitive, psychiatric, and functional measures using K-means cluster analysis in a large PD sample (N=683) and explore subtype-specific prognosis.
Results yielded a two-cluster solution (Cluster 1 N=457; 2 N=226) at baseline with adequate cluster quality. Cluster 1 exhibited more severe rest
tremor but better functioning in all other measures (independence with activities of daily living, daytime sleepiness, depression, anxiety, general non-motor PD symptoms, and postural instability/gait difficulty). Ten half-sample replications of the cluster analysis model and Cohen's kappa revealed excellent model consistency in symptom trends and subjects' cluster membership. Comparison of additional baseline measures using analysis of covariance (ANCOVAs) found that Cluster 1 performed better in overall disease burden, quality of life, motor symptoms, PD medication side effects, mood, sleep dysfunction, compulsive behaviors, psychomotor processing speed, attention, and Aβ-42. ANCOVAs for annualized change showed Cluster 2 exhibiting greater disease burden over time according to a composite measure, with insignificant cluster differences for all other longitudinal analyses. Replication of the cluster analysis model at last visit revealed consistent cluster differences among model measures, but with suboptimal stability over time, as over 25% of subjects changed cluster membership from baseline.
The current study utilized a large and heterogeneous PD sample and a statistically advanced subtyping approach to derive a two-cluster solution, with one group exhibiting relatively greater severity of rest
tremor but better functioning in all other areas used to determine initial group differences, as noted above. Although several significant and clinically manful cluster differences were observed at baseline, longitudinal analyses revealed limited clinical and prognostic usefulness. Future PD subtyping efforts may consider increased variable diversity, novel statistical clustering methodologies, and examining clusters of symptom trajectories rather than baseline symptoms.
Advisors/Committee Members: Lacritz, Laura H., Hynan, Linda S., McClintock, Shawn Michael, Dewey, Richard B., Jr., German, Dwight.
Subjects/Keywords: Cognitive Dysfunction; Muscle Rigidity; Parkinson Disease; Tremor
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Dhima, K. (2018). A Data-Driven Approach for Deriving Parkinson’s Disease Subtypes and Related Trajectories of Cognitive and Motor Function. (Thesis). University of Texas Southwestern Medical Center. Retrieved from http://hdl.handle.net/2152.5/8806
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Dhima, Kaltra. “A Data-Driven Approach for Deriving Parkinson’s Disease Subtypes and Related Trajectories of Cognitive and Motor Function.” 2018. Thesis, University of Texas Southwestern Medical Center. Accessed January 20, 2021.
http://hdl.handle.net/2152.5/8806.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Dhima, Kaltra. “A Data-Driven Approach for Deriving Parkinson’s Disease Subtypes and Related Trajectories of Cognitive and Motor Function.” 2018. Web. 20 Jan 2021.
Vancouver:
Dhima K. A Data-Driven Approach for Deriving Parkinson’s Disease Subtypes and Related Trajectories of Cognitive and Motor Function. [Internet] [Thesis]. University of Texas Southwestern Medical Center; 2018. [cited 2021 Jan 20].
Available from: http://hdl.handle.net/2152.5/8806.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Dhima K. A Data-Driven Approach for Deriving Parkinson’s Disease Subtypes and Related Trajectories of Cognitive and Motor Function. [Thesis]. University of Texas Southwestern Medical Center; 2018. Available from: http://hdl.handle.net/2152.5/8806
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Melbourne
19.
VAN DER WALT, ANNEKE.
Testing paraclinical outcome markers in optic neuritis and a study of the phenomenology and treatment of tremor in multiple sclerosis.
Degree: 2012, University of Melbourne
URL: http://hdl.handle.net/11343/37928
► Multiple Sclerosis (MS) is an autoimmune disease of the central nervous system (CNS) characterised by multi-focal inflammatory demyelinating plaques and significant neuroaxonal degeneration. The clinical…
(more)
▼ Multiple Sclerosis (MS) is an autoimmune disease of the central nervous system (CNS) characterised by multi-focal inflammatory demyelinating plaques and significant neuroaxonal degeneration. The clinical presentation and disease course of MS is heterogeneous and ranges from clinically isolated syndromes such as optic neuritis (ON), to disabling progressive disease at which stage tremor can be a feature. This heterogeneity reflects the multi-focal nature of the CNS injuries and suggests that the relationships between neuronal injury and clinical presentations are complex.
Focused clinical and paraclinical assessments of defined neural pathways associated with discrete clinical presentations can help improve our understanding of complex clinico-pathological relationships. This thesis examined clinical manifestations and outcomes in two models at the opposite ends of the MS clinical spectrum namely acute isolated ON and MS-related tremor. The aims of section one was to comprehensively study changes in clinical and paraclinical markers after ON and more specifically to evaluate the ability of these markers to serve as predictive biomarkers of clinical and axonal outcomes after ON. The second part of this thesis aimed to perform a detailed clinical phenomenology study in MS tremor patients to help define possible underlying neuroanatomical networks and broaden understanding of injury in secondary progressive MS in general. In addition, the efficacy and safety of onabotulinumtoxin-a in the treatment of MS tremor was evaluated.
In Section one, forty patients with acute, idiopathic, unilateral optic neuritis with early MS or at high risk of MS were recruited. Patients were studied prospectively over 12 months at multiple time-points. Ten healthy age and sex-matched controls were tested twice to inspect inter-scan and inter-subject variability. All participants had a detailed neurological assessment, visual acuity testing (high and low-contrast and colour vision), optic nerve diffusion tensor imaging (DTI), multi-focal visual evoked potential (mfVEP), and optical coherence tomography (OCT).
The main outcome measures were 2.5% low contrast visual acuity, mfVEP amplitude and retinal nerve fibre layer thickness (RNFL) at 12 months after ON. Significant changes in clinical and paraclinical measures after ON, particularly in the first 3 months were demonstrated. Despite some initial recovery, persistent visual, functional and neuroaxonal deficits persisted at 12 months. Multivariate models identified decreased high contrast visual acuity (logMAR notation) at 1 month after ON to be the earliest predictor of persistent visual loss at 12 months. Decreased 3-month colour vision and RNFL thickness also both significantly predicted poor visual recovery. The earliest predictors of axonal outcomes at 12 months after ON were decreased 1-month mfVEP amplitude, low contrast acuity and optic nerve axial…
Subjects/Keywords: optic neuritis; multiple sclerosis; MRI; neurodegeneration; tremor
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
VAN DER WALT, A. (2012). Testing paraclinical outcome markers in optic neuritis and a study of the phenomenology and treatment of tremor in multiple sclerosis. (Doctoral Dissertation). University of Melbourne. Retrieved from http://hdl.handle.net/11343/37928
Chicago Manual of Style (16th Edition):
VAN DER WALT, ANNEKE. “Testing paraclinical outcome markers in optic neuritis and a study of the phenomenology and treatment of tremor in multiple sclerosis.” 2012. Doctoral Dissertation, University of Melbourne. Accessed January 20, 2021.
http://hdl.handle.net/11343/37928.
MLA Handbook (7th Edition):
VAN DER WALT, ANNEKE. “Testing paraclinical outcome markers in optic neuritis and a study of the phenomenology and treatment of tremor in multiple sclerosis.” 2012. Web. 20 Jan 2021.
Vancouver:
VAN DER WALT A. Testing paraclinical outcome markers in optic neuritis and a study of the phenomenology and treatment of tremor in multiple sclerosis. [Internet] [Doctoral dissertation]. University of Melbourne; 2012. [cited 2021 Jan 20].
Available from: http://hdl.handle.net/11343/37928.
Council of Science Editors:
VAN DER WALT A. Testing paraclinical outcome markers in optic neuritis and a study of the phenomenology and treatment of tremor in multiple sclerosis. [Doctoral Dissertation]. University of Melbourne; 2012. Available from: http://hdl.handle.net/11343/37928

University of Melbourne
20.
Boonstra, Frederique Maria Christina.
Tremor in multiple sclerosis: neuroimaging perspective.
Degree: 2019, University of Melbourne
URL: http://hdl.handle.net/11343/230596
► Multiple sclerosis (MS) is a common autoimmune disorder of the central nervous system (CNS), characterised by inflammation, demyelination and neurodegeneration. The clinical presentation and disease…
(more)
▼ Multiple sclerosis (MS) is a common autoimmune disorder of the central nervous system (CNS), characterised by inflammation, demyelination and neurodegeneration. The clinical presentation and disease course of MS is heterogeneous, which reflects the multifocal nature of damage within the CNS. Almost half of the MS population experiences a tremor in the later stages of the disease. Tremor significantly increases disease severity and worsens patients’ quality of life. Current understanding of tremor pathophysiology in MS is incomplete and mostly based on treatment studies, clinical observation studies, or neuroimaging studies of parkinsonian tremor and essential tremor. Focused imaging assessments of defined neural pathways associated with tremor can help improve our understanding of complex pathophysiology of MS tremor. This could benefit the current lack of effective, noninvasive and long-term treatment options for tremor.
This thesis provides a comprehensive examination of the pathophysiology of tremor in MS. The first experimental chapter confirms the hypothesis that the cerebello-thalamo-cortical tract is involved in tremor pathophysiology. Specifically, the pilots study finds a positive correlation between thalamic and superior cerebellar peduncle atrophy and tremor severity. In the second experimental chapter, we aimed to develop a functional imaging task that will allow in vivo imaging of tremor pathology. We introduced a novel joystick task, which showed to elicit the MS-related tremor while playing the game. Furthermore, we showed good reproducibility, which is great for the longitudinal part of this thesis. In the third experimental chapter, we applied the joystick imaging task in a large sample of tremor and non-tremor MS patients. We supported that pathology along the cerebello-thalamo-cortical tract is instrumental in tremor pathology. Interestingly, we also found increased functional activation within sensorimotor integration and motor planning areas in MS tremor, which negatively correlated to tremor severity. In the final experimental chapter, we examined the central effects of onabotulinumtoxinA (BoNT-A) for the treatment of tremor in a randomized controlled trial. We found that patients that received BoNT-A had improved tremor and reduced activation within the sensorimotor integration regions. The change in tremor severity correlated with the change in activation, indicated that BoNT-A has a central effect as well as a local effect.
Collectively, these findings suggest that the clinical presentation of tremor in MS is influenced by a tremor network consisting of both structural and functional aspects. Specifically, atrophy and inflammation along the cerebello-thalamo-cortical tract is thought to be more causal to tremor. Contrarily, functional activation is thought to be compensatory to alleviate tremor severity. Intramuscular injection of BoNT-A reduced tremor severity and the activation within the sensorimotor integration area. The central effect of BoNT-A is thought to be due to the lower…
Subjects/Keywords: multiple sclerosis; tremor; MRI; pathophysiology; fMRI
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Boonstra, F. M. C. (2019). Tremor in multiple sclerosis: neuroimaging perspective. (Doctoral Dissertation). University of Melbourne. Retrieved from http://hdl.handle.net/11343/230596
Chicago Manual of Style (16th Edition):
Boonstra, Frederique Maria Christina. “Tremor in multiple sclerosis: neuroimaging perspective.” 2019. Doctoral Dissertation, University of Melbourne. Accessed January 20, 2021.
http://hdl.handle.net/11343/230596.
MLA Handbook (7th Edition):
Boonstra, Frederique Maria Christina. “Tremor in multiple sclerosis: neuroimaging perspective.” 2019. Web. 20 Jan 2021.
Vancouver:
Boonstra FMC. Tremor in multiple sclerosis: neuroimaging perspective. [Internet] [Doctoral dissertation]. University of Melbourne; 2019. [cited 2021 Jan 20].
Available from: http://hdl.handle.net/11343/230596.
Council of Science Editors:
Boonstra FMC. Tremor in multiple sclerosis: neuroimaging perspective. [Doctoral Dissertation]. University of Melbourne; 2019. Available from: http://hdl.handle.net/11343/230596

Georgia Tech
21.
Sun, Wei-Fang.
Detecting deep tectonic tremor in Taiwan using dense arrays.
Degree: MS, Earth and Atmospheric Sciences, 2014, Georgia Tech
URL: http://hdl.handle.net/1853/54251
► Deep tectonic tremor has been observed in major subduction zones, strike-slip faults, inland faulting systems, and arc-continent collision environments around the Pacific Rim. However, detailed…
(more)
▼ Deep tectonic
tremor has been observed in major subduction zones, strike-slip faults, inland faulting systems, and arc-continent collision environments around the Pacific Rim. However, detailed space-time evolution of its source locations remains enigmatic because of difficulties in detecting and locating
tremor accurately. In 2011, we installed two dense, small-aperture seismic arrays aiming to detect ambient
tremor source beneath southern Central Range in Taiwan. We recorded continuous waveforms for a total of 134 days, including
tremor triggered by the great 2011 Mw9.0 Tohoku earthquake. We use the broadband frequency-wavenumber beamforming and the moving-window grid-search methods to compute array parameters for detecting seismic signals. The obtained array parameters closely match both relocated local earthquakes and triggered
tremor bursts located by an envelope cross-correlations method, indicating the robustness of our array technique. We identify
tremor signals with coherent waveforms and deep incidence angles and detect
tremor for 44 days among the 134-day study period. The total duration is 1,481-minute, which is 3-6 times more than that detected by the envelope cross-correlations method. In some cases, we observe rapid
tremor migration with a speed at the order of 40-50 km/hour that is similar to the speed of fast
tremor migration along-dip on narrow streaks in Japan and Cascadia. Our results suggest that dense array techniques are capable of capturing detailed spatiotemporal evolutions of
tremor behaviors in southern Taiwan.
Advisors/Committee Members: Peng, Zhigang (advisor), Newman, Andrew V. (committee member), Huber, Christian (committee member).
Subjects/Keywords: Taiwan; Deep tectonic tremor; Seismic array
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Sun, W. (2014). Detecting deep tectonic tremor in Taiwan using dense arrays. (Masters Thesis). Georgia Tech. Retrieved from http://hdl.handle.net/1853/54251
Chicago Manual of Style (16th Edition):
Sun, Wei-Fang. “Detecting deep tectonic tremor in Taiwan using dense arrays.” 2014. Masters Thesis, Georgia Tech. Accessed January 20, 2021.
http://hdl.handle.net/1853/54251.
MLA Handbook (7th Edition):
Sun, Wei-Fang. “Detecting deep tectonic tremor in Taiwan using dense arrays.” 2014. Web. 20 Jan 2021.
Vancouver:
Sun W. Detecting deep tectonic tremor in Taiwan using dense arrays. [Internet] [Masters thesis]. Georgia Tech; 2014. [cited 2021 Jan 20].
Available from: http://hdl.handle.net/1853/54251.
Council of Science Editors:
Sun W. Detecting deep tectonic tremor in Taiwan using dense arrays. [Masters Thesis]. Georgia Tech; 2014. Available from: http://hdl.handle.net/1853/54251

University of Waterloo
22.
Rahimi, Fariborz.
Tremor in Parkinson's Disease: Loading and Trends in Tremor Characteristics.
Degree: 2010, University of Waterloo
URL: http://hdl.handle.net/10012/5617
► Parkinson's disease (PD) is a neuro-degenerative chronic disorder with cardinal signs of bradykinesia, resting tremor, rigidity, and postural abnormality/instability. Tremor, which is a manifestation of…
(more)
▼ Parkinson's disease (PD) is a neuro-degenerative chronic disorder with cardinal signs of bradykinesia, resting tremor, rigidity, and postural abnormality/instability. Tremor, which is a manifestation of both normal and abnormal activities in the nervous system, can be described as an involuntary and periodic oscillation of any limb. Such an oscillation with a small amplitude, which is barely visible to the naked eye, is present in healthy people. This is called a physiological tremor and is asymptomatic. This tremor is believed to be the result of at least two distinct oscillations. A passive mechanical oscillation that is produced by the irregularities of motor unit firing, and by blood ejection during cardiac systole. The frequency and amplitude of these oscillations are dependent on the mechanical properties of the limb including joint stiffness and limb inertia. There is another component of oscillation that does not respond to elastic or inertial loading, which is called the central component, and is believed to arise from an unknown oscillating neuronal network within the central nervous system. Unlike physiological tremor, pathological tremors are symptomatic and can impair motor performance. Parkinson's disease (PD) tremor is generally manifested at rest, but also occurs during posture or motion. Classical PD rest tremor is known to be a central tremor of 4-6 Hz and peripheral origins have only a minimal role. However, whether or not the same central mechanism remains active during action tremor (including posture and movement) should yet be answered. Contrary to PD rest tremor, reported results on action tremor in the literature are diverse; and the reason for the changes in tremor characteristics in situations other than rest, or generally during muscle activation, is not fully understood. The lack of generality in the results of studies on action tremor, makes the efforts of treatment difficult, and is a barrier for mechanical/engineering approaches of suppressing this tremor. To investigate the role of mechanisms other than classic rest tremor, and possible sub-categories of tremulous PD in yielding diverse results, this study was conducted on twenty PD patients and fourteen healthy age-matched (on average) controls. To evaluate the possible contribution of (enhanced) physiological tremor, the study considered the effect of loading on postural hand tremor in a complete range of 0-100% MVC (Maximum Voluntary Contraction). The study looked at two measures of tremor amplitude and one measure of tremor frequency, and focused on two frequency bands of classic-rest (3.5-6.5 Hz) and physiological (7.5-16.5 Hz) tremors. The study revealed that PD tremor was not uniformly distributed in the three dimensional space, and then focused on the investigation of tremor in the dominant axis, which was the same as direction of loading. It also revealed that dopaminergic medication could significantly affect tremor components only in PD band, compared to the components in the physiological band. The study was an…
Subjects/Keywords: Parkinson's; Tremor; Action tremor; Loading; Physiological tremor; Tremor Energy; Frequency bands
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Rahimi, F. (2010). Tremor in Parkinson's Disease: Loading and Trends in Tremor Characteristics. (Thesis). University of Waterloo. Retrieved from http://hdl.handle.net/10012/5617
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Rahimi, Fariborz. “Tremor in Parkinson's Disease: Loading and Trends in Tremor Characteristics.” 2010. Thesis, University of Waterloo. Accessed January 20, 2021.
http://hdl.handle.net/10012/5617.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Rahimi, Fariborz. “Tremor in Parkinson's Disease: Loading and Trends in Tremor Characteristics.” 2010. Web. 20 Jan 2021.
Vancouver:
Rahimi F. Tremor in Parkinson's Disease: Loading and Trends in Tremor Characteristics. [Internet] [Thesis]. University of Waterloo; 2010. [cited 2021 Jan 20].
Available from: http://hdl.handle.net/10012/5617.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Rahimi F. Tremor in Parkinson's Disease: Loading and Trends in Tremor Characteristics. [Thesis]. University of Waterloo; 2010. Available from: http://hdl.handle.net/10012/5617
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

California State University – Sacramento
23.
Pisolkar, Vaishnavi.
Statistical feature analysis of tremor signal.
Degree: MS, Electrical and Electronic Engineering, 2016, California State University – Sacramento
URL: http://hdl.handle.net/10211.3/182789
► Tremor is an unintentional oscillatory movement of body parts. It is observed in healthy people as well as in people with disorders. While the symptoms…
(more)
▼ Tremor is an unintentional oscillatory movement of body parts. It is observed in healthy
people as well as in people with disorders. While the symptoms are similar,
tremor signals
have different frequencies and amplitudes. The method we proposed is based on higher
order statistics. Power spectrum and bispectrum are two main features of higher order
statistics.
We estimated the bispectrum and power spectrum of
tremor signals and compared these
features for each
subject with and without medication. It was observed that higher
bispectrum and power spectrum correspond to cases without medication.
We also generated an efficient mechanism for performing an analysis on the distribution of
the power spectrum and bispectrum of
tremor signal to examine the influences of gender,
age and the progress of disease under a certain medication condition and evaluate the
success of a treatment.
Advisors/Committee Members: Belkhouche, Fethi.
Subjects/Keywords: Statistical tremor analysis; Bispectrum; Power spectrum; HOS
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Chicago ·
MLA ·
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APA (6th Edition):
Pisolkar, V. (2016). Statistical feature analysis of tremor signal. (Masters Thesis). California State University – Sacramento. Retrieved from http://hdl.handle.net/10211.3/182789
Chicago Manual of Style (16th Edition):
Pisolkar, Vaishnavi. “Statistical feature analysis of tremor signal.” 2016. Masters Thesis, California State University – Sacramento. Accessed January 20, 2021.
http://hdl.handle.net/10211.3/182789.
MLA Handbook (7th Edition):
Pisolkar, Vaishnavi. “Statistical feature analysis of tremor signal.” 2016. Web. 20 Jan 2021.
Vancouver:
Pisolkar V. Statistical feature analysis of tremor signal. [Internet] [Masters thesis]. California State University – Sacramento; 2016. [cited 2021 Jan 20].
Available from: http://hdl.handle.net/10211.3/182789.
Council of Science Editors:
Pisolkar V. Statistical feature analysis of tremor signal. [Masters Thesis]. California State University – Sacramento; 2016. Available from: http://hdl.handle.net/10211.3/182789

California State University – Sacramento
24.
Mudigonda, Swathi Lekha.
Nonlinear time analysis of tremor signals.
Degree: MS, Electrical and Electronic Engineering, 2017, California State University – Sacramento
URL: http://hdl.handle.net/10211.3/182870
► Tremor is a neurological symptom which may result from Parkinson???s disease (PD). The time series specific to tremor is analyzed using tools derived from chaotic…
(more)
▼ Tremor is a neurological symptom which may result from Parkinson???s disease (PD). The time series specific to
tremor is analyzed using tools derived from chaotic analysis, such as Lyapunov exponent, correlation dimension, and capacity dimension. This project focuses on the importance of the nonlinear dynamic parameters in Parkinson???s and essential
tremor.
Nonlinear dynamic parameters such as largest Lyapunov exponent, correlation dimension, and capacity dimension are estimated and plotted to compare the chaotic behavior of Parkinson???s and essential
tremor.
Advisors/Committee Members: Belkhouche, Fethi.
Subjects/Keywords: Parkinson's disease; Essential tremor signals; Lyapunov exponent
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Mudigonda, S. L. (2017). Nonlinear time analysis of tremor signals. (Masters Thesis). California State University – Sacramento. Retrieved from http://hdl.handle.net/10211.3/182870
Chicago Manual of Style (16th Edition):
Mudigonda, Swathi Lekha. “Nonlinear time analysis of tremor signals.” 2017. Masters Thesis, California State University – Sacramento. Accessed January 20, 2021.
http://hdl.handle.net/10211.3/182870.
MLA Handbook (7th Edition):
Mudigonda, Swathi Lekha. “Nonlinear time analysis of tremor signals.” 2017. Web. 20 Jan 2021.
Vancouver:
Mudigonda SL. Nonlinear time analysis of tremor signals. [Internet] [Masters thesis]. California State University – Sacramento; 2017. [cited 2021 Jan 20].
Available from: http://hdl.handle.net/10211.3/182870.
Council of Science Editors:
Mudigonda SL. Nonlinear time analysis of tremor signals. [Masters Thesis]. California State University – Sacramento; 2017. Available from: http://hdl.handle.net/10211.3/182870

University of Georgia
25.
Herring, Matthew P.
The effect of acute resistance exercise on feelings of energy and fatigue.
Degree: 2014, University of Georgia
URL: http://hdl.handle.net/10724/23861
► Purpose: The effect of acute moderate-to-high intensity resistance exercise on energy and fatigue feelings was examined as was resting physiologic tremor as a potential biological…
(more)
▼ Purpose: The effect of acute moderate-to-high intensity resistance exercise on energy and fatigue feelings was examined as was resting physiologic tremor as a potential biological correlate of fatigue feelings. Methods: Fourteen physically
inactive females reporting persistent -1fatigue feelings completed 3 conditions in random order 1 day·week for 3 consecutive weeks. Resting tremor amplitude was assessed before the conditions. Mood was assessed before conditions, every 11 min and 40 s
during, and 20 and 30 min following conditions. Results: Vigor was significantly higher for 70% 1-RM compared to control (t =3.12, p =.01). Fatigue was significantly lower for 15% 1-RM/placebo compared to control (t =-2.59, p =.04). Hand tremor amplitude
was positively correlated with baseline fatigue feelings (r =.36). Conclusions: Acute moderate-to-high intensity resistance exercise increased energy feelings during and following exercise compared to control. Tremor may be a biological correlate of
fatigue feelings.
Subjects/Keywords: Energy; Fatigue; Mood; Tremor; Weight lifting; Vitality
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APA ·
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MLA ·
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Export
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APA (6th Edition):
Herring, M. P. (2014). The effect of acute resistance exercise on feelings of energy and fatigue. (Thesis). University of Georgia. Retrieved from http://hdl.handle.net/10724/23861
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Herring, Matthew P. “The effect of acute resistance exercise on feelings of energy and fatigue.” 2014. Thesis, University of Georgia. Accessed January 20, 2021.
http://hdl.handle.net/10724/23861.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Herring, Matthew P. “The effect of acute resistance exercise on feelings of energy and fatigue.” 2014. Web. 20 Jan 2021.
Vancouver:
Herring MP. The effect of acute resistance exercise on feelings of energy and fatigue. [Internet] [Thesis]. University of Georgia; 2014. [cited 2021 Jan 20].
Available from: http://hdl.handle.net/10724/23861.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Herring MP. The effect of acute resistance exercise on feelings of energy and fatigue. [Thesis]. University of Georgia; 2014. Available from: http://hdl.handle.net/10724/23861
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Queens University
26.
Héroux, Martin.
The effect of contraction type and intensity, mass loading and visual feedback on wrist tremor in individuals with essential tremor
.
Degree: Rehabilitation Science, 2011, Queens University
URL: http://hdl.handle.net/1974/6894
► Objectives: Determine the effect of contraction type and intensity, inertial loading, and visual feedback on various measures of hand tremor in subjects with essential tremor.…
(more)
▼ Objectives: Determine the effect of contraction type and intensity, inertial loading, and visual feedback on various measures of hand tremor in subjects with essential tremor. Methods: Study 1. Twenty-three ET subjects and 22 controls held their hand in an outstretched position while supporting various submaximal loads (no-load, 5%, 15% and 25% 1-repetition maximum). Hand postural tremor and wrist extensor neuromuscular activity (EMG) were recorded. Study 2. Twenty-one ET subjects and 22 controls applied isometric wrist extension contractions with and without visual feedback. Various submaximal contraction intensities were evaluated (5%, 10%, 20% and 30% MVC). Force production and EMG were recorded. Study 3. Twenty-one ET subjects and 22 healthy controls performed slow wrist extension-flexion movements while supporting various submaximal loads (no-load, 5%, 15% and 25% 1-repetition maximum). Angular displacement and EMG were recorded. Results: Study 1. Inertial loading resulted in a reduction in postural tremor in ET subjects. The largest reduction in tremor amplitude occurred at the 15% load, which was associated with spectral separation of the mechanical reflex and central tremor component. Despite an increase in overall neuromuscular activity with inertial loading, EMG tremor power did not increase with loading. Study 2. Higher contraction intensities were associated with larger amplitude force fluctuations and greater EMG amplitudes. Tremor spectral power of force and EMG remained constant at all target intensities, resulting in a reduction in relative tremor power at higher contraction intensities. Visual feedback affected subjects in the control and ET groups similarly. Study 3. Subjects with more pronounced tremor spectral peaks had larger amplitude kinetic tremor, which was reduced with inertial loading. Despite an increase in overall neuromuscular activity with inertial loading, EMG tremor spectral power was only slightly increased with loading, which resulted in a large reduction in relative EMG tremor power. Conclusions: The effect of inertial loading on postural and kinetic tremor amplitude appears to be mediated in large part by its effect on the interaction between the mechanical reflex and central tremor components. The level of motor unit entrainment remains relatively constant in subjects with ET despite increasing contraction intensities.
Subjects/Keywords: essential tremor
;
inertial loading
;
electromyography
;
coherence
;
mechanical reflex
;
postural tremor
;
force fluctuations
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Héroux, M. (2011). The effect of contraction type and intensity, mass loading and visual feedback on wrist tremor in individuals with essential tremor
. (Thesis). Queens University. Retrieved from http://hdl.handle.net/1974/6894
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Héroux, Martin. “The effect of contraction type and intensity, mass loading and visual feedback on wrist tremor in individuals with essential tremor
.” 2011. Thesis, Queens University. Accessed January 20, 2021.
http://hdl.handle.net/1974/6894.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Héroux, Martin. “The effect of contraction type and intensity, mass loading and visual feedback on wrist tremor in individuals with essential tremor
.” 2011. Web. 20 Jan 2021.
Vancouver:
Héroux M. The effect of contraction type and intensity, mass loading and visual feedback on wrist tremor in individuals with essential tremor
. [Internet] [Thesis]. Queens University; 2011. [cited 2021 Jan 20].
Available from: http://hdl.handle.net/1974/6894.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Héroux M. The effect of contraction type and intensity, mass loading and visual feedback on wrist tremor in individuals with essential tremor
. [Thesis]. Queens University; 2011. Available from: http://hdl.handle.net/1974/6894
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Western Ontario
27.
Zhou, Yue.
A Wearable Mechatronic Device for Hand Tremor Monitoring and Suppression: Development and Evaluation.
Degree: 2019, University of Western Ontario
URL: https://ir.lib.uwo.ca/etd/6698
► Tremor, one of the most disabling symptoms of Parkinson's disease (PD), significantly affects the quality of life of the individuals who suffer from it. These…
(more)
▼ Tremor, one of the most disabling symptoms of Parkinson's disease (PD), significantly affects the quality of life of the individuals who suffer from it. These people live with difficulties with fine motor tasks, such as eating and writing, and suffer from social embarrassment. Traditional medicines are often ineffective, and surgery is highly invasive and risky. The emergence of wearable technology facilitates an externally worn mechatronic tremor suppression device as a potential alternative approach for tremor management. However, no device has been developed for the suppression of finger tremor that has been validated on a human.
It has been reported in the literature that tremor can be selectively suppressed by mechanical loading. Therefore, the objectives of this thesis were to develop a wearable tremor suppression device that can suppress tremor at the wrist and the fingers, and to evaluate it on individuals with PD in a pre-clinical trial. To address these objectives, several experiments were performed to quantify hand tremor; an enhanced high-order tremor estimator was developed and evaluated for tremor estimation; and a wearable tremor suppression glove (WTSG) was developed to suppress tremor in the index finger metacarpophalangeal (MCP) joint, the thumb MCP joint, and the wrist.
A total of 18 individuals with PD were recruited for characterizing tremor. The frequencies and magnitudes of the linear acceleration, angular velocity, and angular displacement of tremor in the index finger MCP joint, the thumb MCP joint, and the wrist were quantified. The results showed that parkinsonian tremor consists of multiple harmonics, and that the second and third harmonics cannot be ignored. With the knowledge of the tremor characteristics, an enhanced high-order tremor estimator was developed to acquire better tremor estimation accuracy than its lower-order counterpart.
In addition, the evaluation of the WTSG was conducted on both a physical tremor simulator and on one individual with PD. The results of the simulation study proved the feasibility of using the WTSG to suppress tremor; and the results of the evaluation on a human subject showed that the WTSG can suppress tremor motion while allowing the user to perform voluntary motions. The WTSG developed as a result of this work has demonstrated the feasibility of managing hand tremor with a mechatronic device, and its validation on a human subject has provided useful insights from the user's perspectives,
which facilitate the transition of the WTSG from the lab to the clinic, and eventually to commercial use.
Lastly, an evaluation studying the impact of suppressed tremor on unrestricted joints was conducted on 14 individuals with PD. The results showed a significant increase in tremor magnitude in the unrestricted distal joints when the motions of the proximal joints were restricted. The average increase of the tremor magnitude of the index finger MCP joint, the thumb MCP joint, the wrist and the elbow are 54%, 96%, 124%, and 98% for resting tremor, and 50%, 102%, 49%,…
Subjects/Keywords: Wearable tremor suppression glove; Parkinson's disease; pathological tremor; hand tremor; tremor suppression; assistive device; tremor characterization; tremor estimation; Acoustics, Dynamics, and Controls; Biomedical Devices and Instrumentation; Computer-Aided Engineering and Design; Controls and Control Theory; Electrical and Electronics; Robotics; Signal Processing; Systems and Integrative Engineering
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Zhou, Y. (2019). A Wearable Mechatronic Device for Hand Tremor Monitoring and Suppression: Development and Evaluation. (Thesis). University of Western Ontario. Retrieved from https://ir.lib.uwo.ca/etd/6698
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Zhou, Yue. “A Wearable Mechatronic Device for Hand Tremor Monitoring and Suppression: Development and Evaluation.” 2019. Thesis, University of Western Ontario. Accessed January 20, 2021.
https://ir.lib.uwo.ca/etd/6698.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Zhou, Yue. “A Wearable Mechatronic Device for Hand Tremor Monitoring and Suppression: Development and Evaluation.” 2019. Web. 20 Jan 2021.
Vancouver:
Zhou Y. A Wearable Mechatronic Device for Hand Tremor Monitoring and Suppression: Development and Evaluation. [Internet] [Thesis]. University of Western Ontario; 2019. [cited 2021 Jan 20].
Available from: https://ir.lib.uwo.ca/etd/6698.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Zhou Y. A Wearable Mechatronic Device for Hand Tremor Monitoring and Suppression: Development and Evaluation. [Thesis]. University of Western Ontario; 2019. Available from: https://ir.lib.uwo.ca/etd/6698
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
28.
Karlatec, Damjan.
RAČUNALNIŠKO PODPRTO NEINVAZIVNO VREDNOTENJE DINAMIKE PATOLOŠKEGA TREMORJA V SKELETNIH MIŠICAH.
Degree: 2014, Univerza v Mariboru
URL: https://dk.um.si/IzpisGradiva.php?id=45485
;
https://dk.um.si/Dokument.php?id=66765&dn=
;
https://plus.si.cobiss.net/opac7/bib/18388758?lang=sl
► Patološki tremor je najpogostejša gibalna motnja, ki prizadene okoli 5 % ljudi starejših od 50 let. Zaradi ritmičnega tresenja tako zgornjih kot spodnjih okončin predstavlja…
(more)
▼ Patološki tremor je najpogostejša gibalna motnja, ki prizadene okoli 5 % ljudi starejših od 50 let. Zaradi ritmičnega tresenja tako zgornjih kot spodnjih okončin predstavlja resno funkcionalno motnjo. Bolnike lahko ovira pri vsakodnevnih dejavnostih, v najhujših oblikah pa lahko privede do popolne izgube samostojnosti. V magistrskem delu smo implementirali računalniško podprte postopke za vrednotenje časovne in prostorske dinamike patološkega tremorja iz večkanalnih površinskih signalov EMG ekstenzorjev in fleksorjev zapestja bolnikov s Parkinsonovim in esencialnim tremorjem. Postopke smo vgradili v računalniško aplikacijo, ki omogoča spremljanje amplitude, frekvence in prostorske porazdelitve tremorja v preučevani mišici.
Pathological tremor is the most common movement disorder and affects about 5% of population over the age of 50 years. Because of rhythmic shaking of upper and lower extremities it presents a serious functional disorder that affects practically all the activities of daily living and can, in the worst case, lead to complete loss of autonomy. We implemented a computer-aided procedures for assessment of temporal and spatial dynamics of pathological tremor from multichannel surface EMG signals, recorded from the wrist extensors and flexors in patients with Parkinson's and essential tremor. These procedures were integrated into a computer application, which allows tracking of the tremor amplitude, frequency and spatial distribution in the investigated muscle.
Advisors/Committee Members: Holobar, Aleš.
Subjects/Keywords: Patološki tremor; essencialni tremor; Parkinsonova bolezen; površinski elektromiogram; prostorska dinamika tremorja; ekstenzorji in fleksorji zapestja; inercijske merilne enote; Pathological Tremor; essential tremor; Parkinson's disease; surface electromyogram; spatial dynamics of tremor; wrist extensors and flexors; Inertial Measurement Unit; info:eu-repo/classification/udc/004.777:796.526004.891.3:612.746(043.2)
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Karlatec, D. (2014). RAČUNALNIŠKO PODPRTO NEINVAZIVNO VREDNOTENJE DINAMIKE PATOLOŠKEGA TREMORJA V SKELETNIH MIŠICAH. (Masters Thesis). Univerza v Mariboru. Retrieved from https://dk.um.si/IzpisGradiva.php?id=45485 ; https://dk.um.si/Dokument.php?id=66765&dn= ; https://plus.si.cobiss.net/opac7/bib/18388758?lang=sl
Chicago Manual of Style (16th Edition):
Karlatec, Damjan. “RAČUNALNIŠKO PODPRTO NEINVAZIVNO VREDNOTENJE DINAMIKE PATOLOŠKEGA TREMORJA V SKELETNIH MIŠICAH.” 2014. Masters Thesis, Univerza v Mariboru. Accessed January 20, 2021.
https://dk.um.si/IzpisGradiva.php?id=45485 ; https://dk.um.si/Dokument.php?id=66765&dn= ; https://plus.si.cobiss.net/opac7/bib/18388758?lang=sl.
MLA Handbook (7th Edition):
Karlatec, Damjan. “RAČUNALNIŠKO PODPRTO NEINVAZIVNO VREDNOTENJE DINAMIKE PATOLOŠKEGA TREMORJA V SKELETNIH MIŠICAH.” 2014. Web. 20 Jan 2021.
Vancouver:
Karlatec D. RAČUNALNIŠKO PODPRTO NEINVAZIVNO VREDNOTENJE DINAMIKE PATOLOŠKEGA TREMORJA V SKELETNIH MIŠICAH. [Internet] [Masters thesis]. Univerza v Mariboru; 2014. [cited 2021 Jan 20].
Available from: https://dk.um.si/IzpisGradiva.php?id=45485 ; https://dk.um.si/Dokument.php?id=66765&dn= ; https://plus.si.cobiss.net/opac7/bib/18388758?lang=sl.
Council of Science Editors:
Karlatec D. RAČUNALNIŠKO PODPRTO NEINVAZIVNO VREDNOTENJE DINAMIKE PATOLOŠKEGA TREMORJA V SKELETNIH MIŠICAH. [Masters Thesis]. Univerza v Mariboru; 2014. Available from: https://dk.um.si/IzpisGradiva.php?id=45485 ; https://dk.um.si/Dokument.php?id=66765&dn= ; https://plus.si.cobiss.net/opac7/bib/18388758?lang=sl

Brno University of Technology
29.
Mičánková, Veronika.
Tremometr: Tremometer.
Degree: 2019, Brno University of Technology
URL: http://hdl.handle.net/11012/26167
► Bachelor’s thesis analyzes tremor as a movement disorder and shows its relations to diseases such as Parkinson’s disease, which is therefore described more in detail.…
(more)
▼ Bachelor’s thesis analyzes
tremor as a movement disorder and shows its relations to diseases such as Parkinson’s disease, which is therefore described more in detail. The other part of the work consists of a brief analysis on the physical sensors of vibrations and other methods that can be used to detect vibrations. Practical part is divided into two. First one describes a design of a tremometer and its constructing and the other one describes realization of a program for evaluation of
tremor.
Advisors/Committee Members: Chmelař, Milan (advisor), Harabiš, Vratislav (referee).
Subjects/Keywords: Tremor; Parkinson’s disease; physical sensors; electret microphone; tremometer; LabVIEW; tremor frequency; zero crossing detector.; Tremor; Parkinsonova nemoc; fyzikální senzory; elektretový mikrofon; tremometr; LabVIEW; frekvence třesu; detekce průchodu nulou.
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Mičánková, V. (2019). Tremometr: Tremometer. (Thesis). Brno University of Technology. Retrieved from http://hdl.handle.net/11012/26167
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Mičánková, Veronika. “Tremometr: Tremometer.” 2019. Thesis, Brno University of Technology. Accessed January 20, 2021.
http://hdl.handle.net/11012/26167.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Mičánková, Veronika. “Tremometr: Tremometer.” 2019. Web. 20 Jan 2021.
Vancouver:
Mičánková V. Tremometr: Tremometer. [Internet] [Thesis]. Brno University of Technology; 2019. [cited 2021 Jan 20].
Available from: http://hdl.handle.net/11012/26167.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Mičánková V. Tremometr: Tremometer. [Thesis]. Brno University of Technology; 2019. Available from: http://hdl.handle.net/11012/26167
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Ruhr Universität Bochum
30.
Müller, Inga.
Periphere Beeinflußbarkeit eines zentralen
Tremor-Oszillators durch Gewichtsbelastung : „Loading“ bei Morbus
Parkinson.
Degree: 2003, Ruhr Universität Bochum
URL: http://nbn-resolving.de/urn/resolver.pl?urn=urn:nbn:de:hbz:294-9258
► Der Parkinson-Tremor soll durch einen zentralnervösen Oszillator verursacht sein, der sich von peripher nicht beeinflussen läßt. Es wurde bei 24 Parkinson-Patienten untersucht, ob sich der…
(more)
▼ Der Parkinson-
Tremor soll durch einen
zentralnervösen Oszillator verursacht sein, der sich von peripher
nicht beeinflussen läßt. Es wurde bei 24 Parkinson-Patienten
untersucht, ob sich der
Tremor unter Belastung der zitternden
Extremität mit Gewichten („loading“) ändert. Der
Tremor wurde unter
Haltebedingungen registriert. Dabei wurden Gewichte von 200g bis
1000g in 200g-Schritten in vorbestimmter Reihenfolge eingesetzt. Es
wurde ein Absinken der Frequenz des Parkinson-Tremors unter
Gewichtsbelastung gefunden. Zudem zeigte sich, daß die
Frequenzänderung von der Frequenz des Tremors abhängt: Patienten
mit höheren Ausgangsfrequenzen zeigten eine stärkere
Frequenzabnahme als Patienten mit niedriger Ausgangsfrequenz. Der
Nachweis eines positiven loading-Effektes zeigt, daß der
Parkinson-
Tremor eine periphere Komponente hat. Die Vorstellungen
zur Oszillation beim Parkinson-
Tremor müssen daher um die
Rückkopplung und die Veränderung der peripheren
Schwingungseigenschaften ergänzt werden.
Advisors/Committee Members: Medizin.
Subjects/Keywords: Tremor; Frequenz / Änderung; Tremor / Modell;
Parkinson-Krankheit; Schwingkreis
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Müller, I. (2003). Periphere Beeinflußbarkeit eines zentralen
Tremor-Oszillators durch Gewichtsbelastung : „Loading“ bei Morbus
Parkinson. (Thesis). Ruhr Universität Bochum. Retrieved from http://nbn-resolving.de/urn/resolver.pl?urn=urn:nbn:de:hbz:294-9258
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Müller, Inga. “Periphere Beeinflußbarkeit eines zentralen
Tremor-Oszillators durch Gewichtsbelastung : „Loading“ bei Morbus
Parkinson.” 2003. Thesis, Ruhr Universität Bochum. Accessed January 20, 2021.
http://nbn-resolving.de/urn/resolver.pl?urn=urn:nbn:de:hbz:294-9258.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Müller, Inga. “Periphere Beeinflußbarkeit eines zentralen
Tremor-Oszillators durch Gewichtsbelastung : „Loading“ bei Morbus
Parkinson.” 2003. Web. 20 Jan 2021.
Vancouver:
Müller I. Periphere Beeinflußbarkeit eines zentralen
Tremor-Oszillators durch Gewichtsbelastung : „Loading“ bei Morbus
Parkinson. [Internet] [Thesis]. Ruhr Universität Bochum; 2003. [cited 2021 Jan 20].
Available from: http://nbn-resolving.de/urn/resolver.pl?urn=urn:nbn:de:hbz:294-9258.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Müller I. Periphere Beeinflußbarkeit eines zentralen
Tremor-Oszillators durch Gewichtsbelastung : „Loading“ bei Morbus
Parkinson. [Thesis]. Ruhr Universität Bochum; 2003. Available from: http://nbn-resolving.de/urn/resolver.pl?urn=urn:nbn:de:hbz:294-9258
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
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