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Oregon State University
1.
De Caro Carella, Chiara.
Effect of Intravenous Tiletamine-zolazepam for Induction of General Anesthesia Prior to and during Maintenance with Isoflurane on Cardiorespiratory Parameters and Acid-base Status in Healthy Dogs : A Comparison with Alfaxalone, Ketamine-diazepam, and Propofol.
Degree: MS, Veterinary Science, 2016, Oregon State University
URL: http://hdl.handle.net/1957/59581
► The effects of alfaxalone (A-HPCD), propofol (P), ketamine-diazepam (KD) and tiletamine-zolazepam (TZ) administered IV in dogs on cardiovascular and respiratory systems, acid-base balance and electrolytes…
(more)
▼ The effects of alfaxalone (A-HPCD), propofol (P), ketamine-diazepam (KD) and
tiletamine-
zolazepam (TZ) administered IV in dogs on cardiovascular and respiratory systems, acid-base balance and electrolytes have been reported in the literature, but a study that compares IV TZ to the other induction protocols (IP) is needed. Six dogs enrolled in a randomized-crossover study were anesthetized with sevoflurane and instrumented. After at least 30 minutes post-recovery, baseline values for cardiovascular and respiratory parameters were determined, cardiac output (CO) measured via thermodilution, and arterial (Art) and mixed venous (MV) blood samples collected. Anesthesia was induced with A-HPCD (4 mg/kg), P (6 mg/kg), KD (7 and 0.3 mg/kg, respectively), or TZ (5 mg/kg) administered IV in quarter increments to effect, and maintained with isoflurane (Et[subscript Iso] 1.14 ± 0.32%) for 60 minutes. Immediately post-induction (PI) and at 10, 20, 40, and 60 minutes all measurements were repeated and blood sampled. Derived hemodynamic parameters were calculated. Cardiorespiratory and acid-base parameters compared with RM-ANOVA and a post-hoc t-test were considered significant when p < 0.05. The parameter most affected by protocol was heart rate (HR), with TZ producing the highest HR PI and at 40 and 60 minutes. Oxygen delivery (DO₂) was best maintained by TZ in the first 20 min, while A-HPCD maintained the highest DO₂ at 60 minutes. No significant differences for CO, cardiac index, mean arterial pressure, and systemic vascular resistance were found among IP. Although still within normal limits, mean MV pH, Art and MV potassium were similarly increased with TZ and KD compared to P and A-HPCD. Although statistical significance was found for EtCO₂, pH, lactate, and serum potassium, values stayed in the normal clinical range. TZ produced comparable respiratory changes to KD. Intravenous induction of general anesthesia with TZ maintained on isoflurane is a safe alternative to A-HPCD, KD, and P in healthy dogs and it is recommended for short anesthetic procedures.
Advisors/Committee Members: Mandsager, Ronald E. (advisor), Huber, Michael (committee member).
Subjects/Keywords: Tiletamine-Zolazepam; Veterinary anesthesia
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APA (6th Edition):
De Caro Carella, C. (2016). Effect of Intravenous Tiletamine-zolazepam for Induction of General Anesthesia Prior to and during Maintenance with Isoflurane on Cardiorespiratory Parameters and Acid-base Status in Healthy Dogs : A Comparison with Alfaxalone, Ketamine-diazepam, and Propofol. (Masters Thesis). Oregon State University. Retrieved from http://hdl.handle.net/1957/59581
Chicago Manual of Style (16th Edition):
De Caro Carella, Chiara. “Effect of Intravenous Tiletamine-zolazepam for Induction of General Anesthesia Prior to and during Maintenance with Isoflurane on Cardiorespiratory Parameters and Acid-base Status in Healthy Dogs : A Comparison with Alfaxalone, Ketamine-diazepam, and Propofol.” 2016. Masters Thesis, Oregon State University. Accessed January 16, 2021.
http://hdl.handle.net/1957/59581.
MLA Handbook (7th Edition):
De Caro Carella, Chiara. “Effect of Intravenous Tiletamine-zolazepam for Induction of General Anesthesia Prior to and during Maintenance with Isoflurane on Cardiorespiratory Parameters and Acid-base Status in Healthy Dogs : A Comparison with Alfaxalone, Ketamine-diazepam, and Propofol.” 2016. Web. 16 Jan 2021.
Vancouver:
De Caro Carella C. Effect of Intravenous Tiletamine-zolazepam for Induction of General Anesthesia Prior to and during Maintenance with Isoflurane on Cardiorespiratory Parameters and Acid-base Status in Healthy Dogs : A Comparison with Alfaxalone, Ketamine-diazepam, and Propofol. [Internet] [Masters thesis]. Oregon State University; 2016. [cited 2021 Jan 16].
Available from: http://hdl.handle.net/1957/59581.
Council of Science Editors:
De Caro Carella C. Effect of Intravenous Tiletamine-zolazepam for Induction of General Anesthesia Prior to and during Maintenance with Isoflurane on Cardiorespiratory Parameters and Acid-base Status in Healthy Dogs : A Comparison with Alfaxalone, Ketamine-diazepam, and Propofol. [Masters Thesis]. Oregon State University; 2016. Available from: http://hdl.handle.net/1957/59581

Universidade Federal de Viçosa
2.
Taciana Pereira.
Infusão contínua de remifentanil em cadelas pré-medicadas com levomepromazina e anestesiadas com tiletamina-zolazepam.
Degree: 2008, Universidade Federal de Viçosa
URL: http://www.tede.ufv.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=1715
► A associação tiletamina-zolazepam (T-Z) pertence ao grupo de drogas que promove anestesia do tipo dissociativa. O remifentanil é um opióide μ-agonista, que apresenta grande poder…
(more)
▼ A associação tiletamina-
zolazepam (T-Z) pertence ao grupo de drogas que promove anestesia do tipo dissociativa. O remifentanil é um opióide μ-agonista, que apresenta grande poder analgésico, curto tempo de ação e capacidade de potencializar os anestésicos gerais. O presente trabalho teve como objetivo estudar a infusão contínua de remifentanil em cadelas pré-medicadas com levomepromazina e anestesiadas pela associação T-Z. Foram utilizadas 20 cadelas, distribuídas aleatoriamente em dois grupos de dez animais cada. Após jejum hídrico de 8 horas e alimentar de 12 horas, todos os animais receberam levomepromazina por via intravenosa, na dose de 1,0mg/kg como medicação pré-anestésica (MPA). Decorridos 15 minutos procedeu-se a indução anestésica com a associação T-Z, na dose de 3mg/kg. O Grupo 1 recebeu infusão contínua de solução NaCl 0,9% durante 45 minutos, na velocidade correspondente aos animais do grupo 2 que receberam infusão de remifentanil (0,15ml/kg/min); o Grupo 2 recebeu infusão contínua de remifentanil, na velocidade de 0,3μg/kg/min, durante 45 minutos. Avaliaram-se a temperatura retal, freqüência cardíaca, eletrocardiograma, pressão arterial sistólica, freqüência respiratória, volume minuto, saturação da oxihemoglobina, valores hemogasométricos do sangue arterial, analgesia cirúrgica, com a realização de OSH, miorrelaxamento, reflexos palpebral, corneal, interdigital e laringotraqueal, salivação, período de latência, período hábil, dose total administrada e período de recuperação. Os momentos estabelecidos para mensuração das variáveis foram: Antes Antes da administração da MPA; M1 15 minutos após a MPA; M2 Imediatamente após a indução anestésica e intubação orotraqueal; M3 No momento da ligadura do primeiro pedículo ovariano (aproximadamente 15 minutos após início da infusão); M4 No momento da ligadura do segundo pedículo ovariano (aproximadamente 30 minutos após início da infusão); M5 15 minutos após M4, após o término da cirurgia. Houve queda significativa da temperatura retal em ambos os grupos. Um aumento significativo da freqüência cardíaca e da pressão arterial sistólica também foi observado nos dois grupos porém com maior intensidade no G1. A freqüência respiratória se comportou de maneira diferente nos dois grupos, havendo um aumento no G1 e no G2 a FR manteve-se dentro dos valores fisiológicos. O volume minuto apresentou depressão significativa em ambos os grupos, mas manteve-se dentro dos valores fisiológicos. Não foram observadas diferenças significativas do pH do sangue arterial na comparação entre os grupos. Porém houve diminuição inicial, para depois manter-se estável, sendo que os valores permaneceram na faixa de normalidade, não sendo observada acidemia em nenhum dos dois grupos. O miorrelaxamento e analgesia foram considerados mais intensos no G2. O G1 apresentou período hábil maior e recuperação anestésica mais rápida, em comparação ao G2. A avaliação dos resultados permitiu concluir que: a infusão contínua de remifentanil juntamente com a associação T-Z foi considerada…
Advisors/Committee Members: José Dantas Ribeiro Filho, Andrea Pacheco Batista Borges, Aloísio da Silva Pinto, Eliane Gonçalves de Melo, Ricardo Junqueira Del Carlo, Luiz Gonzaga Pompermayer.
Subjects/Keywords: ANESTESIOLOGIA ANIMAL; Remifentanil; Tiletamina-zolazepam; Cadelas; Remifentanil; Tiletamine-zolazepam; Female dogs
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APA ·
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APA (6th Edition):
Pereira, T. (2008). Infusão contínua de remifentanil em cadelas pré-medicadas com levomepromazina e anestesiadas com tiletamina-zolazepam. (Thesis). Universidade Federal de Viçosa. Retrieved from http://www.tede.ufv.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=1715
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Pereira, Taciana. “Infusão contínua de remifentanil em cadelas pré-medicadas com levomepromazina e anestesiadas com tiletamina-zolazepam.” 2008. Thesis, Universidade Federal de Viçosa. Accessed January 16, 2021.
http://www.tede.ufv.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=1715.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Pereira, Taciana. “Infusão contínua de remifentanil em cadelas pré-medicadas com levomepromazina e anestesiadas com tiletamina-zolazepam.” 2008. Web. 16 Jan 2021.
Vancouver:
Pereira T. Infusão contínua de remifentanil em cadelas pré-medicadas com levomepromazina e anestesiadas com tiletamina-zolazepam. [Internet] [Thesis]. Universidade Federal de Viçosa; 2008. [cited 2021 Jan 16].
Available from: http://www.tede.ufv.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=1715.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Pereira T. Infusão contínua de remifentanil em cadelas pré-medicadas com levomepromazina e anestesiadas com tiletamina-zolazepam. [Thesis]. Universidade Federal de Viçosa; 2008. Available from: http://www.tede.ufv.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=1715
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universidade Federal de Viçosa
3.
Douglas do Carmo Alonso.
Anestesia de animais de laboratório com associação tiletamina-zolazepam em combinação ou não com a levomepromazina.
Degree: 2005, Universidade Federal de Viçosa
URL: http://www.tede.ufv.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=281
► Four species of laboratory animals, mouse (Mus musculus), gerbil (Meriones unguiculatus), hamster (Mesocricetus auratus) and rat (Rattus norvegicus), were submitted to anesthesia with combination of…
(more)
▼ Four species of laboratory animals, mouse (Mus musculus), gerbil (Meriones unguiculatus), hamster (Mesocricetus auratus) and rat (Rattus norvegicus), were submitted to anesthesia with combination of
tiletamine and
zolazepam (TZ) intramuscularly, with or without levomepromazine (LV), in the same syringe. Sixty animals of each specie were divided into six groups with five males and five females. Mice received the following treatments: group1, group2 e group3, with the doses of 40, 60 e 80mg/kg of TZ, respectively, and the groups 1L, 2L e 3L, TZ with the doses of 30, 40 e 50mg/kg respectively, added with 3mg/kg of LV. Gerbils received the following treatments: group1, group2 e group3, with the doses of 50, 60 e 70mg/kg of TZ, respectively, and the groups 1L, 2L e 3L, TZ with the doses of 20, 30 e 40mg/kg respectively, added with 2mg/kg of LV. Hamsters received the following treatments: group1, group2 e group3, with the doses of 180, 300 e 400mg/kg of TZ, respectively, and the groups 1L, 2L e 3L, TZ with the doses of 120, 140 e 160mg/kg respectively, added with 4mg/kg of LV. Rats received the following treatments: group1, group2 e group3, with the doses of 30, 40 e 50mg/kg of TZ, respectively, and the groups 1L, 2L e 3L, TZ with the doses of 20, 30 e 0mg/kg respectively, added with 2mg/kg of LV. Onset of anesthesia, duration of anesthesia, recovery time, posture and other physiological and clinical changing manifested by the animals were evaluated. The analgesia was confirmed when the execution of laparotomy and visceral manipulation was possible. The results in mice showed that even in the higher dose (80mg/kg), TZ was incapable to promote appropriate analgesia and muscular relaxation while the dose of 40mg/kg added of 3mg/kg of LV resulted in adequate anesthesia for the execution of laparotomy. In gerbils, the results demonstrated that even in the higher dose (70mg/kg), the TZ was incapable to promote appropriate analgesia and muscular relaxation, and should be avoided as an anesthetic for painful procedures in gerbils. However when 2mg/kg of LV was added, the dose of 30mg/kg resulted in adequate anesthesia for the execution of laparotomy. In hamsters the TZ promoted surgery anesthesia only in the higher dose (400mg/kg). However, all animals presented respiratory distress and 50% died in the anesthetic period and other 50% in the recovery period, thus the TZ should be avoided as anesthetic in this specie. However when 4mg/kg of LV was added, the 120mg/kg dose resulted in adequate anesthesia for laparotomy. The results with rats showed that even in the higher dose (50mg/kg), the TZ was incapable to promote adequate analgesia and muscular relaxation for abdominal surgery, but when associated the dose of 40mg/kg with LV, an adequate anesthesia for laparotomy occurred. The TZ was incapable to promote appropriate anesthesia for abdominal surgery in any specie, however the LV added to TZ promoted adequate muscular relaxation and analgesia for painful procedures in all the studied species. Any problems or unsuitable effects…
Advisors/Committee Members: Luiz Gonzaga Pompermayer, José Dantas Ribeiro Filho, Andrea Pacheco Batista Borges, Ricardo Junqueira Del Carlo, Aloísio da Silva Pinto.
Subjects/Keywords: CLINICA CIRURGICA ANIMAL; Anestesia; Animais de laboratório; Tiletamina-zolazepam; Fenotiazina; Benzodiazepinas; Anesthesia; Laboratory animals; Tiletamine; Zolazepam
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
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APA (6th Edition):
Alonso, D. d. C. (2005). Anestesia de animais de laboratório com associação tiletamina-zolazepam em combinação ou não com a levomepromazina. (Thesis). Universidade Federal de Viçosa. Retrieved from http://www.tede.ufv.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=281
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Alonso, Douglas do Carmo. “Anestesia de animais de laboratório com associação tiletamina-zolazepam em combinação ou não com a levomepromazina.” 2005. Thesis, Universidade Federal de Viçosa. Accessed January 16, 2021.
http://www.tede.ufv.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=281.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Alonso, Douglas do Carmo. “Anestesia de animais de laboratório com associação tiletamina-zolazepam em combinação ou não com a levomepromazina.” 2005. Web. 16 Jan 2021.
Vancouver:
Alonso DdC. Anestesia de animais de laboratório com associação tiletamina-zolazepam em combinação ou não com a levomepromazina. [Internet] [Thesis]. Universidade Federal de Viçosa; 2005. [cited 2021 Jan 16].
Available from: http://www.tede.ufv.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=281.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Alonso DdC. Anestesia de animais de laboratório com associação tiletamina-zolazepam em combinação ou não com a levomepromazina. [Thesis]. Universidade Federal de Viçosa; 2005. Available from: http://www.tede.ufv.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=281
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universidade Federal de Viçosa
4.
Shirley Miti Nishiyama.
Ketamine-xylazine, tiletamine-zolazepam and tiletamine-zolazepam-levomepromazine combinations in capybara (Hydrochoerus hydrochaeris) anesthesia.
Degree: 2003, Universidade Federal de Viçosa
URL: http://www.tede.ufv.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=702
► Apesar do grande número de criadouros da espécie, a capivara (Hydrochoerus hydrochaeris) ainda é objeto de estudo quanto ao aspecto reprodutivo, ao manejo, à nutrição,…
(more)
▼ Apesar do grande número de criadouros da espécie, a capivara (Hydrochoerus hydrochaeris) ainda é objeto de estudo quanto ao aspecto reprodutivo, ao manejo, à nutrição, e às doenças e agentes a ela relacionados. Seu estudo requer muitas vezes a imobilização química, pois somente a contenção física pode ser fator estressante para o animal e pode colocar em risco a equipe técnica envolvida. A contenção química de capivaras, na prática, é realizada de forma empírica, utilizando-se fármacos e dosagens baseadas em manejos anteriores, que pode resultar em reações inesperadas, indesejáveis e até na morte do animal. Assim, este trabalho teve como objetivos comparar os efeitos das associações cetamina-xilazina, tiletamina-zolazepam e tiletamina-zolazepam-levomepromazina como agentes anestésicos para capivaras. Foram utilizadas 30 capivaras, de ambos os sexos, adultas, com peso médio de 43 kg, distribuídas aleatoriamente em três grupos experimentais de igual número, que receberam as seguintes associações: 10,0 mg/kg de cetamina e 0,5 mg/kg de xilazina (G1); 5,0 mg/kg de tiletamina-zolazepam (G2); 5,0 mg/kg de tiletamina-zolazepam diluídos em 0,5 mg/kg de levomepromazina (G3). Os fármacos foram administrados pela via intramuscular por meio de dardos e zarabatana, e as doses foram calculadas de acordo com o peso estimado dos animais. A dose real administrada foi obtida após imobilização, no momento em que os animais permitiram a pesagem. Foram mensurados a freqüência respiratória, a saturação da oxiemoglobina, a freqüência cardíaca, as pressões arteriais sistólica, média e diastólica, o tempo de perfusão capilar, a temperatura retal, os graus de analgesia e miorrelaxamento e os reflexos protetores no momento em que o animal permitiu a manipulação e após cada 15 minutos, até completar 60 minutos. Avaliaram-se também os períodos de latência, hábil e de recuperação anestésica. Concluiu-se que a associação cetamina-xilazina (10,0 e 0,5 mg/kg, respectivamente) é a mais adequada para analgesia tegumentar, mas quando o tipo de intervenção não exigir analgesia intensa, a dose utilizada da associação tiletamina-zolazepam (5,0 mg/kg) é suficiente para imobilização por cerca de uma hora. A adição da levomepromazina (0,5 mg/kg) melhora a analgesia, o miorrelaxamento, aumenta os períodos hábil e de recuperação tornando-a mais tranqüila. Para intervenções mais cruentas em capivaras serão necessários mais estudos para adequar a dose da associação tiletamina-zolazepam, combinada ou não com a levomepromazina. A utilização do cloridrato de levomepromazina a 0,5% para diluição da forma liofilizada da tiletamina-zolazepam não apresentou nenhum inconveniente e foi vantajoso para uso em dardos, por não aumentar o volume total a ser administrado.
Despite the great number of capybara (Hydrochoerus hydrochaeris) breedings, this species reproduction, handling, nutrition, diseases and its related agents are still studied. Its study requires chemical immobilization specially when the physical restraint can be a stressing factor for the animal and also…
Advisors/Committee Members: Luiz Gonzaga Pompermayer, Tarcízio Antônio Rego de Paula, Andrea Pacheco Batista Borges, Ricardo Junqueira Del Carlo, Deiler Sampaio Costa.
Subjects/Keywords: Hydrochoerus hydrochaeris; Anestesia; Tiletamina-zolazepam-levomepromazina; Capivara; CLINICA E CIRURGIA ANIMAL; Capybara; Tiletamine-zolazepam-levomepromazine; Anesthesia; Hydrochoerus hydrochaeris
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Nishiyama, S. M. (2003). Ketamine-xylazine, tiletamine-zolazepam and tiletamine-zolazepam-levomepromazine combinations in capybara (Hydrochoerus hydrochaeris) anesthesia. (Thesis). Universidade Federal de Viçosa. Retrieved from http://www.tede.ufv.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=702
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Nishiyama, Shirley Miti. “Ketamine-xylazine, tiletamine-zolazepam and tiletamine-zolazepam-levomepromazine combinations in capybara (Hydrochoerus hydrochaeris) anesthesia.” 2003. Thesis, Universidade Federal de Viçosa. Accessed January 16, 2021.
http://www.tede.ufv.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=702.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Nishiyama, Shirley Miti. “Ketamine-xylazine, tiletamine-zolazepam and tiletamine-zolazepam-levomepromazine combinations in capybara (Hydrochoerus hydrochaeris) anesthesia.” 2003. Web. 16 Jan 2021.
Vancouver:
Nishiyama SM. Ketamine-xylazine, tiletamine-zolazepam and tiletamine-zolazepam-levomepromazine combinations in capybara (Hydrochoerus hydrochaeris) anesthesia. [Internet] [Thesis]. Universidade Federal de Viçosa; 2003. [cited 2021 Jan 16].
Available from: http://www.tede.ufv.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=702.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Nishiyama SM. Ketamine-xylazine, tiletamine-zolazepam and tiletamine-zolazepam-levomepromazine combinations in capybara (Hydrochoerus hydrochaeris) anesthesia. [Thesis]. Universidade Federal de Viçosa; 2003. Available from: http://www.tede.ufv.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=702
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Swedish University of Agricultural Sciences
5.
Marntell, Stina.
Sedation and dissociative anaesthesia in the horse.
Degree: 2004, Swedish University of Agricultural Sciences
URL: http://pub.epsilon.slu.se/471/
► The overall aim of this investigation was to study the effects of different drug combinations for premedication and dissociative anaesthesia, to examine their suitability for…
(more)
▼ The overall aim of this investigation was to study the effects of different drug combinations for premedication and dissociative anaesthesia, to examine their suitability for field conditions and their ability to maintain cardiorespiratory function and provide sufficient analgesia for common, but challenging procedures such as castration. Haemodynamic parameters, pulmonary ventilation-perfusion relationships, and clinical effects were studied during sedation and dissociative anaesthesia. The effects of additional premedication and prolongation of dissociative anaesthesia and response to surgery were evaluated. The cardiorespiratory effects of romifidine and tiletamine-zolazepam anaesthesia did not differ significantly from those of prolonged romifidine and ketamine anaesthesia. Prolongation of anaesthesia with ketamine alone after romifidine/ketamine resulted in a poor quality of anaesthesia. There was a decrease in arterial oxygenation during sedation with a2-agonists, which was mainly attributed to a reduced cardiac output and increased ventilation-perfusion mismatch. During dissociative anaesthesia the cardiac output did normalise, but arterial oxygenation was further impaired as a result of increased intrapulmonary shunt and increased ventilation-perfusion mismatch. Administration of acepromazine before sedation with romifidine and butorphanol resulted in better maintenance of circulation and partly prevented the anaesthesia-induced ventilation-perfusion disturbances and fall in arterial oxygen tension. Although the arterial oxygenation was further impaired during anaesthesia and recumbency compared to that during sedation, the oxygen delivery did not decrease further. On the contrary, the arterial-mixed venous oxygen content difference and mixed venous oxygen tension remained closer to standing unsedated values during anaesthesia than in the sedated horse. Breathing high oxygen concentrations (>95% oxygen) during dissociative anaesthesia improved arterial oxygenation compared to air breathing (21% oxygen), but concomitantly increased intrapulmonary shunt and introduced hypoventilation. The intrapulmonary shunt created during anaesthesia with high oxygen concentrations persisted when the horses returned to air breathing, possibly indicating that resorption atelectasis produced during high oxygen breathing subsequently persisted during anaesthesia and recumbency. Tiletamine-zolazepam anaesthesia, after premedication with acepromazine, romifidine and butorphanol, produced anaesthesia and analgesia sufficient for castration of colts under field conditions. When the same regimen was used in the animal hospital there was a need for supplementary anaesthesia in some cases to complete surgery. The induction, anaesthesia and recovery were calm and without excitation in all colts both under hospital and field conditions. Cardiorespiratory changes during air breathing were within acceptable limits in these clinically healthy horses.
Subjects/Keywords: horses; anaesthesia; respiration; analgesics; ketamine; oxygen; therapy; horses; field anaesthesia; additional premedication; prolonging dissociative anaesthesia; respiration; circulation; pulmonary gas exchange; intrapulmonary shunt; a2-agonists; butorphanol; acepromazine; ketamine; diazepam; tiletamine; zolazepam
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Marntell, S. (2004). Sedation and dissociative anaesthesia in the horse. (Doctoral Dissertation). Swedish University of Agricultural Sciences. Retrieved from http://pub.epsilon.slu.se/471/
Chicago Manual of Style (16th Edition):
Marntell, Stina. “Sedation and dissociative anaesthesia in the horse.” 2004. Doctoral Dissertation, Swedish University of Agricultural Sciences. Accessed January 16, 2021.
http://pub.epsilon.slu.se/471/.
MLA Handbook (7th Edition):
Marntell, Stina. “Sedation and dissociative anaesthesia in the horse.” 2004. Web. 16 Jan 2021.
Vancouver:
Marntell S. Sedation and dissociative anaesthesia in the horse. [Internet] [Doctoral dissertation]. Swedish University of Agricultural Sciences; 2004. [cited 2021 Jan 16].
Available from: http://pub.epsilon.slu.se/471/.
Council of Science Editors:
Marntell S. Sedation and dissociative anaesthesia in the horse. [Doctoral Dissertation]. Swedish University of Agricultural Sciences; 2004. Available from: http://pub.epsilon.slu.se/471/
6.
McKenzie, Jane.
Population demographics of New Zealand fur seals (Arctocephalus forsteri).
Degree: 2006, La Trobe University
URL: http://www.lib.latrobe.edu.au./thesis/public/adt-LTU20080509.121141
► Assessment of trophic interactions between increasing populations of New Zealand fur seals (Arctocephalus forsteri) and fisheries in southern Australia is limited due to a lack…
(more)
▼ Assessment of trophic interactions between increasing populations of New Zealand fur seals (Arctocephalus forsteri) and fisheries in southern Australia is limited due to a lack of species specific demographic data and an understanding of the factors influencing population growth. To establish species specific demographic parameters a cross-sectional sample of New Zealand fur seal females (330) and males (100) were caught and individually-marked on Kangaroo Island, South Australia between 2000 and 2003. The seals were aged through examination of a postcanine tooth, which was removed from each animal to investigate age-specific life-history parameters. Annual formation of cementum layers was confirmed and accuracy in age estimation was determined by examination of teeth removed from individuals of known-age. Indirect methods of assessing reproductive maturity based on mammary teat characteristics indicated that females first gave birth between 4-8 years of age, with an average age at reproductive maturity of 5 years. Among reproductively mature females, age-specific reproductive rates increased rapidly between 4-7 years of age, reaching maximum rates of 70-81% between 8-13 years, and gradually decreased in older females. No females older than 22 years were recorded to pup. Age of first territory tenure in males ranged from 8-10 years. The oldest female and male were 25 and 19 years old, respectively. Post-weaning growth in females was monophasic, characterised by high growth rates in length and mass during the juvenile growth stage, followed by a gradual decline in growth rates after reproductive maturity. In contrast, growth in males was biphasic and displayed a secondary growth spurt in both length and mass, which coincided with sexual and social maturation, followed by a rapid decline in growth rates. Age-specific survival rates were high (0.823-0.953) among prime-age females (8-13 yrs of age) and declined in older females. Relative change in annual pup production was strongly correlated with reproductive rates of prime-age females and adult female survival between breeding seasons.
Subjects/Keywords: New Zealand fur seal; Kangaroo Island - South Australia; New Zealand fur seal - Population viability analysis; New Zealand fur seal - Breeding; Fisheries - South Australia - Environmental variability; Marine mammal populations; Pinniped; otarid; remote chemical immobilization; darting; anaesthesia; isoflurane; midazolam; zoletil; tiletamine-zolazepam; restraint; behavioral response; fecundity; pregnancy rates; progesterone; reproduction; reproductive failure; site fidelity; mortality; territorial; size dimorphism; life table; ageing; growth layer groups; re-colonization
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
McKenzie, J. (2006). Population demographics of New Zealand fur seals (Arctocephalus forsteri). (Thesis). La Trobe University. Retrieved from http://www.lib.latrobe.edu.au./thesis/public/adt-LTU20080509.121141
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
McKenzie, Jane. “Population demographics of New Zealand fur seals (Arctocephalus forsteri).” 2006. Thesis, La Trobe University. Accessed January 16, 2021.
http://www.lib.latrobe.edu.au./thesis/public/adt-LTU20080509.121141.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
McKenzie, Jane. “Population demographics of New Zealand fur seals (Arctocephalus forsteri).” 2006. Web. 16 Jan 2021.
Vancouver:
McKenzie J. Population demographics of New Zealand fur seals (Arctocephalus forsteri). [Internet] [Thesis]. La Trobe University; 2006. [cited 2021 Jan 16].
Available from: http://www.lib.latrobe.edu.au./thesis/public/adt-LTU20080509.121141.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
McKenzie J. Population demographics of New Zealand fur seals (Arctocephalus forsteri). [Thesis]. La Trobe University; 2006. Available from: http://www.lib.latrobe.edu.au./thesis/public/adt-LTU20080509.121141
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Latrobe University
7.
McKenzie, Jane.
Population demographics of New Zealand fur seals (Arctocephalus forsteri).
Degree: 2006, Latrobe University
URL: http://hdl.handle.net/1959.9/468696
► Assessment of trophic interactions between increasing populations of New Zealand fur seals (Arctocephalus forsteri) and fisheries in southern Australia is limited due to a lack…
(more)
▼ Assessment of trophic interactions between increasing populations of New Zealand fur seals (Arctocephalus forsteri) and fisheries in southern Australia is limited due to a lack of species specific demographic data and an understanding of the factors influencing population growth. To establish species specific demographic parameters a cross-sectional sample of New Zealand fur seal females (330) and males (100) were caught and individually-marked on Kangaroo Island, South Australia between 2000 and 2003. The seals were aged through examination of a postcanine tooth, which was removed from each animal to investigate age-specific life-history parameters. Annual formation of cementum layers was confirmed and accuracy in age estimation was determined by examination of teeth removed from individuals of known-age.Indirect methods of assessing reproductive maturity based on mammary teat characteristics indicated that females first gave birth between 4-8 years of age, with an average age at reproductive maturity of 5 years. Among reproductively mature females, age-specific reproductive rates increased rapidly between 4-7 years of age, reaching maximum rates of 70-81% between 8-13 years, and gradually decreased in older females. No females older than 22 years were recorded to pup. Age of first territory tenure in males ranged from 8-10 years. The oldest female and male were 25 and 19 years old, respectively. Post-weaning growth in females was monophasic, characterised by high growth rates in length and mass during the juvenile growth stage, followed by a gradual decline in growth rates after reproductive maturity.In contrast, growth in males was biphasic and displayed a secondary growth spurt in both length and mass, which coincided with sexual and social maturation, followed by a rapid decline in growth rates. Age-specific survival rates were high (0.823-0.953) among prime-age females (8-13yrs of age) and declined in older females. Relative change in annual pup production was strongly correlated with reproductive rates of prime-age females and adult female survival between breeding seasons.
Subjects/Keywords: Pinniped; otarid; remote chemical immobilization; darting; anaesthesia; isoflurane; midazolam; zoletil; tiletamine-zolazepam; restraint; behavioral response; fecundity; pregnancy rates; progesterone; reproduction; reproductive failure; site fidelity; mortality; territorial; size dimorphism; life table; ageing; growth layer groups; re-colonization; New Zealand fur seal – South Australia – Kangaroo Island; New Zealand fur seal – Population viability analysis – South Australia – Kangaroo Island; New Zealand fur seal – Breeding – South Australia – Kangaroo Island; Fisheries – South Australia – Environmental aspects; Marine mammal populations – South Australia – Kangaroo Island
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share





❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
McKenzie, J. (2006). Population demographics of New Zealand fur seals (Arctocephalus forsteri). (Thesis). Latrobe University. Retrieved from http://hdl.handle.net/1959.9/468696
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
McKenzie, Jane. “Population demographics of New Zealand fur seals (Arctocephalus forsteri).” 2006. Thesis, Latrobe University. Accessed January 16, 2021.
http://hdl.handle.net/1959.9/468696.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
McKenzie, Jane. “Population demographics of New Zealand fur seals (Arctocephalus forsteri).” 2006. Web. 16 Jan 2021.
Vancouver:
McKenzie J. Population demographics of New Zealand fur seals (Arctocephalus forsteri). [Internet] [Thesis]. Latrobe University; 2006. [cited 2021 Jan 16].
Available from: http://hdl.handle.net/1959.9/468696.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
McKenzie J. Population demographics of New Zealand fur seals (Arctocephalus forsteri). [Thesis]. Latrobe University; 2006. Available from: http://hdl.handle.net/1959.9/468696
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
.