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You searched for subject:(tenascin r). Showing records 1 – 2 of 2 total matches.

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1. El Ayachi, Ikbale. KIAA 0510, Ténascine R, et astrocytomes pilocytiques : KIAA 0510, Tenascin R and pilocytic astrocytomas.

Degree: Docteur es, Neurosciences, 2010, Aix-Marseille 2

Les gliomes sont les tumeurs primitives les plus fréquentes du système nerveux central. Cette dernière décennie, l’apport de la biologie moléculaire a permis de mieux appréhender leurs comportements et de mieux préciser leur origine. Nous avons montré que le profil moléculaire des glioblastomes (grade IV dans la classification de l’OMS) et celui des astrocytomes pilocytiques (grade I dans la classification de l’OMS) différait notamment par l’expression d’un gène nommé KIAA 0510. La caractérisation de sa séquence nous a mené à nous intéresser à la Ténascine R, une glycoprotéine de la matrice extracellulaire impliquée dans les processus de migration et de différenciation cellulaire. Par ailleurs, l’expression de la Ténascine R pendant le développement, suggère son implication au cours de la corticogenèse.Dans le but de mieux comprendre l’origine des astrocytomes pilocytiques, notamment ceux de la région des voies optiques, nous avons mis en évidence au niveau du chiasma optique en développement des cellules de la glie radiaire à partir desquelles les astrocytomes pilocytiques des voies optiques pourraient dériver.

Gliomas are the most frequently occurring primary tumors in the central nervous system. These last years, molecular biology technics allowed a better understanding of the gliomagenesis as well as behaviour of these tumors. We have previously shown that molecular profiling of glioblastomes (WHO grade IV) and pilocytic astrocytomas (WHO grade I) differed for KIAA 0510 gene expression. This sequence was fully characterized and shown to be part of the tenascin R gene encoding for an extracellular matrix glycoprotein involved in migration and cell differentiation. In addition, during development, Tenascin-R may be involved in corticogenesis.In parallel, in the developing optic chiasm, we evidenced cells with radial glial characteristics from which the hypothalamo-chiasmatic pilocytic astrocytomas could derive.

Advisors/Committee Members: Figarella-Branger, Dominique (thesis director).

Subjects/Keywords: Kiaa 0510; Ténascine R; Astrocytome pilocytique; Matrice extracellulaire; Corticogenèse; Kiaa 0510; Tenascin R; Pilocytic astrocytomas; Extracellular matrix; Corticogenesis

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APA (6th Edition):

El Ayachi, I. (2010). KIAA 0510, Ténascine R, et astrocytomes pilocytiques : KIAA 0510, Tenascin R and pilocytic astrocytomas. (Doctoral Dissertation). Aix-Marseille 2. Retrieved from http://www.theses.fr/2010AIX20684

Chicago Manual of Style (16th Edition):

El Ayachi, Ikbale. “KIAA 0510, Ténascine R, et astrocytomes pilocytiques : KIAA 0510, Tenascin R and pilocytic astrocytomas.” 2010. Doctoral Dissertation, Aix-Marseille 2. Accessed January 19, 2020. http://www.theses.fr/2010AIX20684.

MLA Handbook (7th Edition):

El Ayachi, Ikbale. “KIAA 0510, Ténascine R, et astrocytomes pilocytiques : KIAA 0510, Tenascin R and pilocytic astrocytomas.” 2010. Web. 19 Jan 2020.

Vancouver:

El Ayachi I. KIAA 0510, Ténascine R, et astrocytomes pilocytiques : KIAA 0510, Tenascin R and pilocytic astrocytomas. [Internet] [Doctoral dissertation]. Aix-Marseille 2; 2010. [cited 2020 Jan 19]. Available from: http://www.theses.fr/2010AIX20684.

Council of Science Editors:

El Ayachi I. KIAA 0510, Ténascine R, et astrocytomes pilocytiques : KIAA 0510, Tenascin R and pilocytic astrocytomas. [Doctoral Dissertation]. Aix-Marseille 2; 2010. Available from: http://www.theses.fr/2010AIX20684

2. LEE KIA MING PATRICK. CHARACTERISATION OF STRUCTURAL PLASTICITY OF THE VISUAL CORTEX IN PRMT8 NULL MICE?.

Degree: 2016, National University of Singapore

Subjects/Keywords: neuroepigenetics; perineuronal nets; protein arginine methyltransferase; proteomics; tenascin-r; visual cortex

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

PATRICK, L. K. M. (2016). CHARACTERISATION OF STRUCTURAL PLASTICITY OF THE VISUAL CORTEX IN PRMT8 NULL MICE?. (Thesis). National University of Singapore. Retrieved from http://scholarbank.nus.edu.sg/handle/10635/135183

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

PATRICK, LEE KIA MING. “CHARACTERISATION OF STRUCTURAL PLASTICITY OF THE VISUAL CORTEX IN PRMT8 NULL MICE?.” 2016. Thesis, National University of Singapore. Accessed January 19, 2020. http://scholarbank.nus.edu.sg/handle/10635/135183.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

PATRICK, LEE KIA MING. “CHARACTERISATION OF STRUCTURAL PLASTICITY OF THE VISUAL CORTEX IN PRMT8 NULL MICE?.” 2016. Web. 19 Jan 2020.

Vancouver:

PATRICK LKM. CHARACTERISATION OF STRUCTURAL PLASTICITY OF THE VISUAL CORTEX IN PRMT8 NULL MICE?. [Internet] [Thesis]. National University of Singapore; 2016. [cited 2020 Jan 19]. Available from: http://scholarbank.nus.edu.sg/handle/10635/135183.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

PATRICK LKM. CHARACTERISATION OF STRUCTURAL PLASTICITY OF THE VISUAL CORTEX IN PRMT8 NULL MICE?. [Thesis]. National University of Singapore; 2016. Available from: http://scholarbank.nus.edu.sg/handle/10635/135183

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

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