subject:(surrogate)

1. Sharma, Richa. Keratinases from pseudomonas aeruginosa KS-1: Characterization and degradation of surrogate prion protein Sup 35NM; -.

Degree: Microbiology, 2012, University of Delhi

URL: http://shodhganga.inflibnet.ac.in/handle/10603/18010

►

Keratinases are a special group of proteases which are well recognized for their action newlineon recalcitrant proteins such as feather, nail, hair, hoof etc. They… (more)

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Keratinases are a special group of proteases which are well recognized for their action newlineon recalcitrant proteins such as feather, nail, hair, hoof etc. They are lately being recognized newlineas potential catalysts for degradation of prion. Few keratinases have already been newlinedocumented to degrade prion however treatment of the infected tissue with harsh alkali or at newlinehigh temperature is required. This limits the applicability of these enzymes. Thus, the need of newlinethe hour is to search for efficient keratinases which can degrade prion under ambient newlineconditions. newlineLooking into the above, the present investigation was undertaken to search for a newlinepotential prion degrading keratinase. Fifty feather degrading bacterial isolates were screened, newlineout of which eleven were selected as they could degrade chicken feather within 48 h. Among newlinethese, extracellular broth of nine isolates carried out cell free feather degradation. Isolate KS- newline1 which maximally degraded Sup 35NM was finally selected for further studies. It was newlineidentified as Pseudomonas aeruginosa and deposited to MTCC under the accession number newline10775. newlineTwo keratinases, KP1 and KP2 of 45kDa and 33kDa respectively were purified from newlineits extracellular broth. Keratinase KP1 shared homology with putative aminopeptidase while newlinekeratinase KP2 gave homology with pseudolysin. Keratinase KP1 was alkaline, serine, metal newlineactivated protease and KP2 was a neutral, thiol-activated, serine protease. Both the enzymes newlinewere extremely thermostable. K:C (keratinolytic: caseinolytic) ratio of 2.5 and 0.9 for KP1 newlineand KP2 respectively. Both also efficiently hydrolyzed p-nitroanilides with best activity on newlineN-Suc-Ala-Ala-Pro-Phe-pNA. They had unique activity on the synthetic substrate of plasmin. newlineHydrolysis of insulin B chain revealed KP1 and KP2 to have four and six cleavage sites newlinerespectively. newlineBoth the keratinases were constitutively expressed as extracellular proteins using newlinepEZZ18-E. coli HB101 system. Biochemical characterization the pH and temperature optima newlineof rKP1 and rKP2 to be pH 10.0/60 °C

Bibliography p.196-207

Advisors/Committee Members: Gupta, Rani.

Subjects/Keywords: Microbiology; surrogate; protein

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APA (6^th Edition):

Sharma, R. (2012). Keratinases from pseudomonas aeruginosa KS-1: Characterization and degradation of surrogate prion protein Sup 35NM; -. (Thesis). University of Delhi. Retrieved from http://shodhganga.inflibnet.ac.in/handle/10603/18010

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Sharma, Richa. “Keratinases from pseudomonas aeruginosa KS-1: Characterization and degradation of surrogate prion protein Sup 35NM; -.” 2012. Thesis, University of Delhi. Accessed January 28, 2021. http://shodhganga.inflibnet.ac.in/handle/10603/18010.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Sharma, Richa. “Keratinases from pseudomonas aeruginosa KS-1: Characterization and degradation of surrogate prion protein Sup 35NM; -.” 2012. Web. 28 Jan 2021.

Vancouver:

Sharma R. Keratinases from pseudomonas aeruginosa KS-1: Characterization and degradation of surrogate prion protein Sup 35NM; -. [Internet] [Thesis]. University of Delhi; 2012. [cited 2021 Jan 28]. Available from: http://shodhganga.inflibnet.ac.in/handle/10603/18010.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Sharma R. Keratinases from pseudomonas aeruginosa KS-1: Characterization and degradation of surrogate prion protein Sup 35NM; -. [Thesis]. University of Delhi; 2012. Available from: http://shodhganga.inflibnet.ac.in/handle/10603/18010

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Ottawa

2. Khan, Maryam. Validation of Surrogate Outcomes: Application to Biomarkers of Atherosclerosis .

Degree: 2011, University of Ottawa

URL: http://hdl.handle.net/10393/19963

► Statement of the problem: Many methods for surrogate outcome validation require individual patient data which is often inaccessible by clinical trialists. Methods: A review was… (more)

Subjects/Keywords: surrogate outcomes; atherosclerosis

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APA (6^th Edition):

Khan, M. (2011). Validation of Surrogate Outcomes: Application to Biomarkers of Atherosclerosis . (Thesis). University of Ottawa. Retrieved from http://hdl.handle.net/10393/19963

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Khan, Maryam. “Validation of Surrogate Outcomes: Application to Biomarkers of Atherosclerosis .” 2011. Thesis, University of Ottawa. Accessed January 28, 2021. http://hdl.handle.net/10393/19963.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Khan, Maryam. “Validation of Surrogate Outcomes: Application to Biomarkers of Atherosclerosis .” 2011. Web. 28 Jan 2021.

Vancouver:

Khan M. Validation of Surrogate Outcomes: Application to Biomarkers of Atherosclerosis . [Internet] [Thesis]. University of Ottawa; 2011. [cited 2021 Jan 28]. Available from: http://hdl.handle.net/10393/19963.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Khan M. Validation of Surrogate Outcomes: Application to Biomarkers of Atherosclerosis . [Thesis]. University of Ottawa; 2011. Available from: http://hdl.handle.net/10393/19963

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Notre Dame

3. Juan Diwu. Comparison of Transuranium Elements and Their Proposed Surrogates</h1>.

Degree: Civil Engineering and Geological Sciences, 2012, University of Notre Dame

URL: https://curate.nd.edu/show/9880vq3010c

► Transuranium elements, especially plutonium, play a special role in science and politics, due to their importance in both nuclear weapons and nuclear industry. However,… (more)

▼ Transuranium elements, especially plutonium, play a special role in science and politics, due to their importance in both nuclear weapons and nuclear industry. However, owing to the radioactivity and toxicity of actinides there are severe restrictions regarding their storage, use, and disposal. One of the outcomes of this is the use of less toxic and less or non-radioactive surrogates for transuranium elements. The most central question is: do these surrogates actually mimic the chemistry of transuranics? In this present work we probe the structural chemistry of actinide diphosphonates to address this aforementioned question. In this research, the surrogates chosen are Ln(III) (Ln=La~Lu) for the An(III) (An= Pu, Am, Cm), Ce(IV), Th(IV) and U(IV) for Np(IV) and Pu(IV), and UO22+ for PuO22+. The ligands used in this research are methylenediphosphonic acid (C1P2) and phenylenediphosphonic acid (PhP2). Hydrothermal reactions, room temperature evaporations, as well as ionothermal reactions were conducted to study the interaction between these two ligands react with the transuranic elements and their surrogates, the difference and similairy between transuranic diphosphonates and their surrogates in terms of structural topology. To further illustrate the properties of those synthetic compounds, the following characterization techniques are used. The single crystal X-Ray Diffraction and powder X-Ray Diffraction experiments are conducted to explore the structure details of the products. For the elemental analysis, Inductively Coupled Plasma-Mass Spectrum (ICP-MS) and Energy-dispersive X-ray spectroscopy (EDS) techniques are utilized. Spectroscopic techniques like UV-vis-NIR are applied to identify the oxidation states for actinide elements. As a result, in total 99 diphosphonate compounds were synthesized to fulfill this task. The structural types vary from zero-dimensional clusters, one-dimensional chains, two-dimensional layers to three-dimensional frameworks. The oxidation states of those transuranic elements involved are from trivalent to hexavalent. Such results offer a great opportunity for a thorough comparison of transuranic elements with their surrogates in different structure topologies and oxidation states in the diphosphonate system. Besides the comparison study, many new actinide compounds were synthesized with special properties. For example, two chiral, porous uranium metheylenediphosphonates were crystallized with channels about 1nm×1nm wide, large enough to conduct ion-exchange with coordination complexes such as [Co(en)3]3+. The Bond Valence parameters for Pu(IV), Np(IV) and Np(VI) was calculated and reported to assist the study the chemistry of transuranic elements. Advisors/Committee Members: Jeremy B. Fein, Committee Member, Peter C. Burns, Committee Member, Thomas E. Albrecht-Schmitt, Committee Chair, Antonio Simonetti, Committee Member.

Subjects/Keywords: surrogate; phosphonate; actinide

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APA (6^th Edition):

Diwu, J. (2012). Comparison of Transuranium Elements and Their Proposed Surrogates</h1>. (Thesis). University of Notre Dame. Retrieved from https://curate.nd.edu/show/9880vq3010c

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Diwu, Juan. “Comparison of Transuranium Elements and Their Proposed Surrogates</h1>.” 2012. Thesis, University of Notre Dame. Accessed January 28, 2021. https://curate.nd.edu/show/9880vq3010c.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Diwu, Juan. “Comparison of Transuranium Elements and Their Proposed Surrogates</h1>.” 2012. Web. 28 Jan 2021.

Vancouver:

Diwu J. Comparison of Transuranium Elements and Their Proposed Surrogates</h1>. [Internet] [Thesis]. University of Notre Dame; 2012. [cited 2021 Jan 28]. Available from: https://curate.nd.edu/show/9880vq3010c.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Diwu J. Comparison of Transuranium Elements and Their Proposed Surrogates</h1>. [Thesis]. University of Notre Dame; 2012. Available from: https://curate.nd.edu/show/9880vq3010c

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Georgia Tech

4. Wen, Yuchen. Stream of variation and shape control for composite fuselage assembly.

Degree: PhD, Industrial and Systems Engineering, 2018, Georgia Tech

URL: http://hdl.handle.net/1853/62617

► Composite parts have been increasingly used in aerospace industry because of their high strength-to-weight ratio and stiffness-to-weight ratio. Due to the diversity of suppliers and… (more)

▼ Composite parts have been increasingly used in aerospace industry because of their high strength-to-weight ratio and stiffness-to-weight ratio. Due to the diversity of suppliers and variation in the fabrication process of composite parts, dimensional variability of composite fuselages inevitably exists. One of the critical challenges to reduce the dimensional variability of the assembly process is the complex property of composite materials. The traditional physical models applied to metal materials cannot be directly applied here. It is of high importance to develop systematic methodologies to conduct dimensional analysis, variation reduction, and optimal shape adjustment for the composite fuselages’ assembly process. Based on these motivations, this dissertation focuses on developing systematic methodologies for effective system modeling, quality control and variability reduction in the composite fuselages assembly process. These advanced methodologies enable a better understanding of the composite fuselage structure with actuator applied, a more accurate handling of the fuselage shape control system, and a more precise way to analyze the residual stress during the fuselage assembly process. This dissertation is organized as follows. Chapter 1 introduces a new shape control system with 10 actuators that is able to conduct dimensional shape adjustment before the airplane fuselage assembly process. In Chapter 2, a feasibility study is conducted to evaluate the proposed shape control concept. In the feasibility analysis, an accurate finite element model is developed to mimic the fabrication of composite fuselage, which includes the detailed materials setting, ply design, geometry and fixture structures. The finite element model is validated and calibrated based on physical experimental data with a real fuselage on the production floor. The results show that the single-plane with ten actuators scheme is feasible for shape control, and that actuators do not damage the fuselage. In Chapter 3, a surrogate model considering four types of uncertainties (actuator uncertainty, part uncertainty, modeling uncertainty, and unquantified uncertainty) has been developed for automatic optimal shape control of the system proposed in Chapter 2. A maximum likelihood estimation (MLE) algorithm is used for parameter estimation and response prediction. Afterwards, the surrogated model considering uncertainties is embedded into a feedforward control algorithm, which is achieved by conducting multivariate optimization to minimize the weighted summation of dimensional deviations of the response from the target. We show that the surrogate model considering uncertainties achieves satisfactory prediction performance and the automated optimal shape control system can significantly reduce the assembly cycle time with improved dimensional quality. In Chapter 4, two active learning algorithms are proposed for Gaussian process considering uncertainties, which are the variance-based weighted active learning algorithm and D-optimal weighted active… Advisors/Committee Members: Shi, Jianjun (advisor), Wang, Ben (committee member), Paynabar, Kamran (committee member), Zhang, Chuck (committee member), Jin, Judy (committee member).

Subjects/Keywords: Finite element analysis; Surrogate model

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APA (6^th Edition):

Wen, Y. (2018). Stream of variation and shape control for composite fuselage assembly. (Doctoral Dissertation). Georgia Tech. Retrieved from http://hdl.handle.net/1853/62617

Chicago Manual of Style (16^th Edition):

Wen, Yuchen. “Stream of variation and shape control for composite fuselage assembly.” 2018. Doctoral Dissertation, Georgia Tech. Accessed January 28, 2021. http://hdl.handle.net/1853/62617.

MLA Handbook (7^th Edition):

Wen, Yuchen. “Stream of variation and shape control for composite fuselage assembly.” 2018. Web. 28 Jan 2021.

Vancouver:

Wen Y. Stream of variation and shape control for composite fuselage assembly. [Internet] [Doctoral dissertation]. Georgia Tech; 2018. [cited 2021 Jan 28]. Available from: http://hdl.handle.net/1853/62617.

Council of Science Editors:

Wen Y. Stream of variation and shape control for composite fuselage assembly. [Doctoral Dissertation]. Georgia Tech; 2018. Available from: http://hdl.handle.net/1853/62617

Texas A&M University

5. Intikhab, Saad. An Experimentally Verified Approach to Design Efficient Gasoline and Diesel Fuel Surrogates.

Degree: MS, Chemical Engineering, 2016, Texas A&M University

URL: http://hdl.handle.net/1969.1/156889

► Gasoline or diesel fuel sourced from crude oil source is a complex mixture of hundreds of hydrocarbons. It is extremely difficult to simulate for better… (more)

▼ Gasoline or diesel fuel sourced from crude oil source is a complex mixture of hundreds of hydrocarbons. It is extremely difficult to simulate for better understanding of the fuel flow and combustion behaviors which are essential to enhance fuel quality and to improve engine performance. To overcome this difficulty, a surrogate fuel, that has fewer compounds and that emulates certain important physical properties of a target fuel, can be utilized. The surrogate mixtures for both gasoline and diesel are designed through a computer aided model based technique by our collaborator at Technical University of Denmark (DTU), and their relevant target properties are predicted. Following the preparation of surrogate blends, target physical properties of both fuel surrogates are measured according to American Society of Testing and Materials (ASTM) methods using advanced analytical equipment in the Fuel Characterization Laboratory. For both gasoline and diesel surrogates, the model predictions are found to be in good agreement with the experimental results except for a few reported cases such as the Reid Vapor Pressure (RVP) of gasoline. For such cases, modifications are made to the model in order to improve the predicted results. Therefore, the experimental investigations are found to be extremely essential for improving the assumptions used to define interactions of the hydrocarbons in the mixtures, which in turn enables enhanced predictability of the model. The developed model, which leads to a property driven product, can be further investigated to prepare new fuel blends and identify suitable renewable additives in a known amount that can aid in designing of future generation of fuels obtained from either conventional crude oil sources or non-conventional sources. Even though this model provides an excellent, fast and reliable opportunity for screening large number of fuel surrogates and optimization of the same, it is extremely important to experimentally verify the final blends and fine-tune them if necessary before their utilization in engine. Also, the measured property values help to improve the accuracy of the property models as well as the assumptions used to develop them. Advisors/Committee Members: Elbashir, Nimir (advisor), Abdel-Wahab, Ahmed (advisor), Abu-Rub, Haitham (committee member).

Subjects/Keywords: gasoline; diesel; surrogate; physical properties

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Intikhab, S. (2016). An Experimentally Verified Approach to Design Efficient Gasoline and Diesel Fuel Surrogates. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/156889

Chicago Manual of Style (16^th Edition):

Intikhab, Saad. “An Experimentally Verified Approach to Design Efficient Gasoline and Diesel Fuel Surrogates.” 2016. Masters Thesis, Texas A&M University. Accessed January 28, 2021. http://hdl.handle.net/1969.1/156889.

MLA Handbook (7^th Edition):

Intikhab, Saad. “An Experimentally Verified Approach to Design Efficient Gasoline and Diesel Fuel Surrogates.” 2016. Web. 28 Jan 2021.

Vancouver:

Intikhab S. An Experimentally Verified Approach to Design Efficient Gasoline and Diesel Fuel Surrogates. [Internet] [Masters thesis]. Texas A&M University; 2016. [cited 2021 Jan 28]. Available from: http://hdl.handle.net/1969.1/156889.

Council of Science Editors:

Intikhab S. An Experimentally Verified Approach to Design Efficient Gasoline and Diesel Fuel Surrogates. [Masters Thesis]. Texas A&M University; 2016. Available from: http://hdl.handle.net/1969.1/156889

McMaster University

6. Liu, Yumeng. Impact of Informative Censoring on Statistics Used in the Validation of Surrogate Endpoints in Oncology.

Degree: MSc, 2014, McMaster University

URL: http://hdl.handle.net/11375/16576

►

In the past few years, biomarkers such as progression free survival (PFS) and time to progression (TTP), have been increasingly used as surrogate endpoints for… (more)

Subjects/Keywords: informative censoring; surrogate endpoint

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APA (6^th Edition):

Liu, Y. (2014). Impact of Informative Censoring on Statistics Used in the Validation of Surrogate Endpoints in Oncology. (Masters Thesis). McMaster University. Retrieved from http://hdl.handle.net/11375/16576

Chicago Manual of Style (16^th Edition):

Liu, Yumeng. “Impact of Informative Censoring on Statistics Used in the Validation of Surrogate Endpoints in Oncology.” 2014. Masters Thesis, McMaster University. Accessed January 28, 2021. http://hdl.handle.net/11375/16576.

MLA Handbook (7^th Edition):

Liu, Yumeng. “Impact of Informative Censoring on Statistics Used in the Validation of Surrogate Endpoints in Oncology.” 2014. Web. 28 Jan 2021.

Vancouver:

Liu Y. Impact of Informative Censoring on Statistics Used in the Validation of Surrogate Endpoints in Oncology. [Internet] [Masters thesis]. McMaster University; 2014. [cited 2021 Jan 28]. Available from: http://hdl.handle.net/11375/16576.

Council of Science Editors:

Liu Y. Impact of Informative Censoring on Statistics Used in the Validation of Surrogate Endpoints in Oncology. [Masters Thesis]. McMaster University; 2014. Available from: http://hdl.handle.net/11375/16576

University of Tasmania

7. Maddock, M-V. Surrogate motherhood : an acceptable solution for infertile couples?.

Degree: 1988, University of Tasmania

URL: https://eprints.utas.edu.au/20258/1/whole_MaddockMaria-Veronika1988_thesis.pdf

► It has been variously estimated that one out of six couples or 15-20 percent of couples, are infertile. The changes in social attitudes and social… (more)

▼ It has been variously estimated that one out of six couples or 15-20 percent of couples, are infertile. The changes in social attitudes and social welfare policies towards single mothers together with the increased use of contraception and abortion mean that the demand for adoptable babies now surpasses the supply. Those infertile couples who are frustrated by the long adoption procedures and are unable to be helped through the Artificial Insemination by Donor (AID) or In Vitro Fertilization (IVF) programmes are turning in increasing numbers to a practice with a long history which has only recently gained world-wide attention - the practice of surrogate motherhood. The practice of surrogacy dates back at least to Biblical times. One of the first recorded instances is found in the Old Testament. Almost 4 000 years ago Sarah, the wife of Abraham, could not conceive and sent her husband to her Egyptian maid Hagar saying "It may be that I may obtain children by her". Hagar thus bore Ismael. Another example is that of Rachel, wife of Jacob, who required Billa to "bear upon my knees that I may also have a child by her". Jacob's other wife, Leah, had the same arrangement with her slave-girl Zilpah. Today, surrogate motherhood has provoked considerable debate on the moral, ethical, legal, and social consequences, issues to which existing legislation has failed adequately to address itself. In a jurisdiction where no specific legislation on surrogacy exists, the application of existing laws produce distorted results which are beyond the probable legislative intent. Where specific legislation prohibits the practice of surrogacy, it has failed to recognize long term implications of such prohibition. Most of the known cases of surrogacy arrangements involve the insemination of the surrogate with the sperm of the husband of the infertile couple. The insemination of the surrogate with the sperm of a person other than the husband of the infertile couple is, of course, a possibility, but would probably be a method resorted to only where both the wife and husband are infertile. In this case, the resultant child has no genetic link with his intended parents. The expression infertile couple in this paper is used to denote a couple where the wife is incapable of bearing, or carrying to term, a child. Discussion in this paper is limited to infertile couples who participate in surrogacy arrangements by the most common means of the artificial insemination of the surrogate by the sperm of the husband. It is by the use of such a practice that the major ethical and legal issues arise. Recent developments in the field of In Vitro Fertilization now enable an embryo to be implanted in a woman who is not the genetic mother of the embryo. In the case of a surrogacy arrangement, the surrogate becomes the gestational or 'host' mother and where the couple have both contributed the genetic material, they are the genetic parents. Three other possibilities become available with the use of the technique of embryo transfer. The first is where an…

Subjects/Keywords: Surrogate motherhood

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APA (6^th Edition):

Maddock, M. (1988). Surrogate motherhood : an acceptable solution for infertile couples?. (Thesis). University of Tasmania. Retrieved from https://eprints.utas.edu.au/20258/1/whole_MaddockMaria-Veronika1988_thesis.pdf

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Maddock, M-V. “Surrogate motherhood : an acceptable solution for infertile couples?.” 1988. Thesis, University of Tasmania. Accessed January 28, 2021. https://eprints.utas.edu.au/20258/1/whole_MaddockMaria-Veronika1988_thesis.pdf.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Maddock, M-V. “Surrogate motherhood : an acceptable solution for infertile couples?.” 1988. Web. 28 Jan 2021.

Vancouver:

Maddock M. Surrogate motherhood : an acceptable solution for infertile couples?. [Internet] [Thesis]. University of Tasmania; 1988. [cited 2021 Jan 28]. Available from: https://eprints.utas.edu.au/20258/1/whole_MaddockMaria-Veronika1988_thesis.pdf.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Maddock M. Surrogate motherhood : an acceptable solution for infertile couples?. [Thesis]. University of Tasmania; 1988. Available from: https://eprints.utas.edu.au/20258/1/whole_MaddockMaria-Veronika1988_thesis.pdf

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Durham University

8. Everett, Pauline. A relational defence of surrogate motherhood.

Degree: PhD, 2011, Durham University

URL: http://etheses.dur.ac.uk/4464/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.694796

► This thesis explores surrogate motherhood using Christian ethics within a relational framework. A surrogate mother is a woman who has a child for a commissioning… (more)

Subjects/Keywords: 248.8; Surrogacy. Surrogate Motherhood.

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APA (6^th Edition):

Everett, P. (2011). A relational defence of surrogate motherhood. (Doctoral Dissertation). Durham University. Retrieved from http://etheses.dur.ac.uk/4464/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.694796

Chicago Manual of Style (16^th Edition):

Everett, Pauline. “A relational defence of surrogate motherhood.” 2011. Doctoral Dissertation, Durham University. Accessed January 28, 2021. http://etheses.dur.ac.uk/4464/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.694796.

MLA Handbook (7^th Edition):

Everett, Pauline. “A relational defence of surrogate motherhood.” 2011. Web. 28 Jan 2021.

Vancouver:

Everett P. A relational defence of surrogate motherhood. [Internet] [Doctoral dissertation]. Durham University; 2011. [cited 2021 Jan 28]. Available from: http://etheses.dur.ac.uk/4464/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.694796.

Council of Science Editors:

Everett P. A relational defence of surrogate motherhood. [Doctoral Dissertation]. Durham University; 2011. Available from: http://etheses.dur.ac.uk/4464/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.694796

Delft University of Technology

9. Wolken, M. (author). Energy dissipation response of a rectangular metal tube on axial impact.

Degree: 2017, Delft University of Technology

URL: http://resolver.tudelft.nl/uuid:379da7cb-abf9-4f5d-84bd-2957fb7aafd5

►

A surrogate model is used to predict the energy dissipation response for a rectangular beam, initiated by an axial impact. This method is used for… (more)

Subjects/Keywords: Impact; surrogate model; energy dissipation

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APA (6^th Edition):

Wolken, M. (. (2017). Energy dissipation response of a rectangular metal tube on axial impact. (Masters Thesis). Delft University of Technology. Retrieved from http://resolver.tudelft.nl/uuid:379da7cb-abf9-4f5d-84bd-2957fb7aafd5

Chicago Manual of Style (16^th Edition):

Wolken, M (author). “Energy dissipation response of a rectangular metal tube on axial impact.” 2017. Masters Thesis, Delft University of Technology. Accessed January 28, 2021. http://resolver.tudelft.nl/uuid:379da7cb-abf9-4f5d-84bd-2957fb7aafd5.

MLA Handbook (7^th Edition):

Wolken, M (author). “Energy dissipation response of a rectangular metal tube on axial impact.” 2017. Web. 28 Jan 2021.

Vancouver:

Wolken M(. Energy dissipation response of a rectangular metal tube on axial impact. [Internet] [Masters thesis]. Delft University of Technology; 2017. [cited 2021 Jan 28]. Available from: http://resolver.tudelft.nl/uuid:379da7cb-abf9-4f5d-84bd-2957fb7aafd5.

Council of Science Editors:

Wolken M(. Energy dissipation response of a rectangular metal tube on axial impact. [Masters Thesis]. Delft University of Technology; 2017. Available from: http://resolver.tudelft.nl/uuid:379da7cb-abf9-4f5d-84bd-2957fb7aafd5

Delft University of Technology

10. Deshmukh, Piyush (author). MDO with composite aeroelastic tailoring.

Degree: 2020, Delft University of Technology

URL: http://resolver.tudelft.nl/uuid:deb6815e-0f79-4571-b607-c4d051f1f755

►

With the focus on the reduction of fossil fuel emissions, aircraft are continuously growing towards higher fuel efficiency. The traditional limits of aircraft performance can… (more)

Subjects/Keywords: KADMOS; surrogate modeling; Composites; PROTEUS

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APA (6^th Edition):

Deshmukh, P. (. (2020). MDO with composite aeroelastic tailoring. (Masters Thesis). Delft University of Technology. Retrieved from http://resolver.tudelft.nl/uuid:deb6815e-0f79-4571-b607-c4d051f1f755

Chicago Manual of Style (16^th Edition):

Deshmukh, Piyush (author). “MDO with composite aeroelastic tailoring.” 2020. Masters Thesis, Delft University of Technology. Accessed January 28, 2021. http://resolver.tudelft.nl/uuid:deb6815e-0f79-4571-b607-c4d051f1f755.

MLA Handbook (7^th Edition):

Deshmukh, Piyush (author). “MDO with composite aeroelastic tailoring.” 2020. Web. 28 Jan 2021.

Vancouver:

Deshmukh P(. MDO with composite aeroelastic tailoring. [Internet] [Masters thesis]. Delft University of Technology; 2020. [cited 2021 Jan 28]. Available from: http://resolver.tudelft.nl/uuid:deb6815e-0f79-4571-b607-c4d051f1f755.

Council of Science Editors:

Deshmukh P(. MDO with composite aeroelastic tailoring. [Masters Thesis]. Delft University of Technology; 2020. Available from: http://resolver.tudelft.nl/uuid:deb6815e-0f79-4571-b607-c4d051f1f755

11. Bark, Charles. CLINICAL SYMPTOMS AND MICROBIOLOGICAL OUTCOMES IN TUBERCULOSIS TREATMENT TRIALS.

Degree: MSs, Epidemiology and Biostatistics, 2011, Case Western Reserve University School of Graduate Studies

URL: http://rave.ohiolink.edu/etdc/view?acc_num=case1307630776

► During a recent Federal Drug Administration workshop on tuberculosis trials, questions were raised regarding the use of bacteriologic surrogate endpoints. FDA scientists asked if these… (more)

Subjects/Keywords: Medicine; tuberculosis; symptoms; surrogate endpoints

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APA (6^th Edition):

Bark, C. (2011). CLINICAL SYMPTOMS AND MICROBIOLOGICAL OUTCOMES IN TUBERCULOSIS TREATMENT TRIALS. (Masters Thesis). Case Western Reserve University School of Graduate Studies. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=case1307630776

Chicago Manual of Style (16^th Edition):

Bark, Charles. “CLINICAL SYMPTOMS AND MICROBIOLOGICAL OUTCOMES IN TUBERCULOSIS TREATMENT TRIALS.” 2011. Masters Thesis, Case Western Reserve University School of Graduate Studies. Accessed January 28, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=case1307630776.

MLA Handbook (7^th Edition):

Bark, Charles. “CLINICAL SYMPTOMS AND MICROBIOLOGICAL OUTCOMES IN TUBERCULOSIS TREATMENT TRIALS.” 2011. Web. 28 Jan 2021.

Vancouver:

Bark C. CLINICAL SYMPTOMS AND MICROBIOLOGICAL OUTCOMES IN TUBERCULOSIS TREATMENT TRIALS. [Internet] [Masters thesis]. Case Western Reserve University School of Graduate Studies; 2011. [cited 2021 Jan 28]. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=case1307630776.

Council of Science Editors:

Bark C. CLINICAL SYMPTOMS AND MICROBIOLOGICAL OUTCOMES IN TUBERCULOSIS TREATMENT TRIALS. [Masters Thesis]. Case Western Reserve University School of Graduate Studies; 2011. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=case1307630776

University of Victoria

12. Fisher, Ann Muriel. A Narrative inquiry: how surrogate mothers make meaning of the gestational surrogacy experience.

Degree: School of Child and Youth Care, 2012, University of Victoria

URL: http://hdl.handle.net/1828/3820

► Research about gestational surrogacy is limited from the surrogate’s perspective, yet third party reproduction is on the rise worldwide, and specifically in Canada. The experiences,… (more)

Subjects/Keywords: Surrogacy; Surrogate Motherhood; Surrogacy Narratives; Gestational Surrogate; Gestational Surrogacy

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APA (6^th Edition):

Fisher, A. M. (2012). A Narrative inquiry: how surrogate mothers make meaning of the gestational surrogacy experience. (Masters Thesis). University of Victoria. Retrieved from http://hdl.handle.net/1828/3820

Chicago Manual of Style (16^th Edition):

Fisher, Ann Muriel. “A Narrative inquiry: how surrogate mothers make meaning of the gestational surrogacy experience.” 2012. Masters Thesis, University of Victoria. Accessed January 28, 2021. http://hdl.handle.net/1828/3820.

MLA Handbook (7^th Edition):

Fisher, Ann Muriel. “A Narrative inquiry: how surrogate mothers make meaning of the gestational surrogacy experience.” 2012. Web. 28 Jan 2021.

Vancouver:

Fisher AM. A Narrative inquiry: how surrogate mothers make meaning of the gestational surrogacy experience. [Internet] [Masters thesis]. University of Victoria; 2012. [cited 2021 Jan 28]. Available from: http://hdl.handle.net/1828/3820.

Council of Science Editors:

Fisher AM. A Narrative inquiry: how surrogate mothers make meaning of the gestational surrogacy experience. [Masters Thesis]. University of Victoria; 2012. Available from: http://hdl.handle.net/1828/3820

University of Iowa

13. Zhao, Liang. Reliability-based design optimization using surrogate model with assessment of confidence level.

Degree: PhD, Mechanical Engineering, 2011, University of Iowa

URL: https://ir.uiowa.edu/etd/1194

► The objective of this study is to develop an accurate surrogate modeling method for construction of the surrogate model to represent the performance measures… (more)

▼ The objective of this study is to develop an accurate surrogate modeling method for construction of the surrogate model to represent the performance measures of the compute-intensive simulation model in reliability-based design optimization (RBDO). In addition, an assessment method for the confidence level of the surrogate model and a conservative surrogate model to account the uncertainty of the prediction on the untested design domain when the number of samples are limited, are developed and integrated into the RBDO process to ensure the confidence of satisfying the probabilistic constraints at the optimal design. The effort involves: (1) developing a new surrogate modeling method that can outperform the existing surrogate modeling methods in terms of accuracy for reliability analysis in RBDO; (2) developing a sampling method that efficiently and effectively inserts samples into the design domain for accurate surrogate modeling; (3) generating a surrogate model to approximate the probabilistic constraint and the sensitivity of the probabilistic constraint with respect to the design variables in most-probable-point-based RBDO; (4) using the sampling method with the surrogate model to approximate the performance function in sampling-based RBDO; (5) generating a conservative surrogate model to conservatively approximate the performance function in sampling-based RBDO and assure the obtained optimum satisfy the probabilistic constraints. In applying RBDO to a large-scale complex engineering application, the surrogate model is commonly used to represent the compute-intensive simulation model of the performance function. However, the accuracy of the surrogate model is still challenging for highly nonlinear and large dimension applications. In this work, a new method, the Dynamic Kriging (DKG) method is proposed to construct the surrogate model accurately. In this DKG method, a generalized pattern search algorithm is used to find the accurate optimum for the correlation parameter, and the optimal mean structure is set using the basis functions that are selected by a genetic algorithm from the candidate basis functions based on a new accuracy criterion. Plus, a sequential sampling strategy based on the confidence interval of the surrogate model from the DKG method, is proposed. By combining the sampling method with the DKG method, the efficiency and accuracy can be rapidly achieved. Using the accurate surrogate model, the most-probable-point (MPP)-based RBDO and the sampling-based RBDO can be carried out. In applying the surrogate models to MPP-based RBDO and sampling-based RBDO, several efficiency strategies, which include: (1) using local window for surrogate modeling; (2) adaptive window size for different design candidates; (3) reusing samples in the local window; (4) using violated constraints for surrogate model accuracy check; (3) adaptive initial point for correlation parameter estimation, are proposed. To assure the accuracy of the surrogate model when the number of samples is limited,… Advisors/Committee Members: Choi, Kyung K. (supervisor).

Subjects/Keywords: confidence; conservative surrogate model; dynamic kriging; rbdo; surrogate modeling; Mechanical Engineering

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APA (6^th Edition):

Zhao, L. (2011). Reliability-based design optimization using surrogate model with assessment of confidence level. (Doctoral Dissertation). University of Iowa. Retrieved from https://ir.uiowa.edu/etd/1194

Chicago Manual of Style (16^th Edition):

Zhao, Liang. “Reliability-based design optimization using surrogate model with assessment of confidence level.” 2011. Doctoral Dissertation, University of Iowa. Accessed January 28, 2021. https://ir.uiowa.edu/etd/1194.

MLA Handbook (7^th Edition):

Zhao, Liang. “Reliability-based design optimization using surrogate model with assessment of confidence level.” 2011. Web. 28 Jan 2021.

Vancouver:

Zhao L. Reliability-based design optimization using surrogate model with assessment of confidence level. [Internet] [Doctoral dissertation]. University of Iowa; 2011. [cited 2021 Jan 28]. Available from: https://ir.uiowa.edu/etd/1194.

Council of Science Editors:

Zhao L. Reliability-based design optimization using surrogate model with assessment of confidence level. [Doctoral Dissertation]. University of Iowa; 2011. Available from: https://ir.uiowa.edu/etd/1194

University of Texas – Austin

14. Kohli, Namita. Going Into labor: (un)making mothers in India's transnational surrogacy markets.

Degree: MA, Women's and Gender Studies, 2013, University of Texas – Austin

URL: http://hdl.handle.net/2152/41475

► In this study, I am concerned with the practices of representation and labor control that enable the extraction of value from the bodies of working… (more)

▼ In this study, I am concerned with the practices of representation and labor control that enable the extraction of value from the bodies of working class women in India’s transnational surrogacy markets. Recent ethnographic studies on transnational surrogacy in India have conceptualized surrogacy as a form of waged labor and focused on critically examining the structure of surrogacy markets and the production of mother-workers. This study builds on these ethnographic approaches towards surrogacy as labor, and analyzes the discourses and the practices of labor control that enable service providers to extract value from the women’s bodies; a large part of this value accrues from their treatment as disposable. I begin by analyzing the discourses around surrogate mothers in three key sites of representation, that is, the news media, service provider websites and the draft legislation that is set to regulate the use of assisted reproductive technologies in India. Subsequently, I critically examine my interactions with service providers in New Delhi to unearth the mechanisms of disciplining and surveillance that are used to control, discipline and ensure productivity of the surrogate labor. My findings suggest that surrogate mothers are always framed within the competing discourses of “exploitation” and “empowerment” in the press, while the service providers represent them within the frames of “opportunity”. In the draft legislation, the rights of surrogate mothers are based on the market-based assumptions about reproductive autonomy and the disposability of working class women’s bodies. A critical examination of my interactions with service providers, and their recruitment and disciplining strategies, reveals the ways by which labor is effectively disciplined and controlled for value extraction. Thus, this study highlights some of the ways by which working class women’s labor is exploited and their bodies are treated as disposable. Future studies should attend to the ways in which the surrogate mothers experience these practices that they are subject to and whether, or not, disrupt the production of the “ideal” mother-worker. Advisors/Committee Members: Rudrappa, Sharmila, 1966- (advisor), Visweswaran, Kamala (committee member).

Subjects/Keywords: Surrogate mothers; Labor; Transnational surrogacy; Surrogate mothers India

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APA (6^th Edition):

Kohli, N. (2013). Going Into labor: (un)making mothers in India's transnational surrogacy markets. (Masters Thesis). University of Texas – Austin. Retrieved from http://hdl.handle.net/2152/41475

Chicago Manual of Style (16^th Edition):

Kohli, Namita. “Going Into labor: (un)making mothers in India's transnational surrogacy markets.” 2013. Masters Thesis, University of Texas – Austin. Accessed January 28, 2021. http://hdl.handle.net/2152/41475.

MLA Handbook (7^th Edition):

Kohli, Namita. “Going Into labor: (un)making mothers in India's transnational surrogacy markets.” 2013. Web. 28 Jan 2021.

Vancouver:

Kohli N. Going Into labor: (un)making mothers in India's transnational surrogacy markets. [Internet] [Masters thesis]. University of Texas – Austin; 2013. [cited 2021 Jan 28]. Available from: http://hdl.handle.net/2152/41475.

Council of Science Editors:

Kohli N. Going Into labor: (un)making mothers in India's transnational surrogacy markets. [Masters Thesis]. University of Texas – Austin; 2013. Available from: http://hdl.handle.net/2152/41475

University of California – Berkeley

15. Pozzi, Luca. Topics in Evidence Synthesis.

Degree: Biostatistics, 2014, University of California – Berkeley

URL: http://www.escholarship.org/uc/item/1b61431k

► This dissertation considers three different topics related to extracting and merging evidence from heterogeneous sources. This problem is addressed from different angles, from the field… (more)

▼ This dissertation considers three different topics related to extracting and merging evidence from heterogeneous sources. This problem is addressed from different angles, from the field of design of experiment to machine learning.Within this dissertation, we add to the existing literature in each area by developing novel methodology and software. Adaptive trial designs can considerably improve upon traditional designs,by modifying design aspects of the ongoing trial, like early stopping,adding or dropping doses, or changing the sample size. We propose a two-stage Bayesian adaptive design for a Phase IIb study aimed at selecting the lowest effective dose for Phase III. In this setting, efficacy has been proved for a high dose in a Phase IIa proof-of-concept study, but the existence of alower but still effective dose is investigated before the scheduled Phase III starts.In the first stage patients are randomized to placebo, maximaltolerated dose, and one or more additional doses within the doserange. Based on an interim analysis, the study is either stopped forfutility or success, or enters the second stage, where newly recruitedpatients are allocated to placebo, some fairly high dose, and oneadditional dose chosen based on interim data. At the interim analysiscriteria based on the predictive probability of success are used todecide on whether to stop or to continue the trial, and, in the lattercase, which dose to select for the second stage.Finally, a dose will be selected as lowest effective dose for Phase IIIeither at the end of the first or at the end of the second stage. The operating characteristics of the procedure are evaluated viasimulations and results are presented for several scenarios comparingthe performance of the proposed procedure to those of the non adaptivedesign.The development of novel therapies in multiple sclerosis (MS) is one area where a range of surrogateoutcomes are used in various stages of clinical research. While the aim of treatments in MS is to preventdisability, a clinical trial for evaluating a drugs effect on disability progression would require a largesample of patients with many years of follow-up. The early stage of MS is characterized by relapses. Toreduce study size and duration, clinical relapses are accepted as primary endpoints in phase III trials. Forphase II studies, the primary outcomes are typically lesion counts based on Magnetic Resonance Imaging(MRI), as these are considerably more sensitive than clinical measures for detecting MS activity.Recently, Sormani and colleagues provided a systematic review, andused weighted regression analyses to examine the role of either MRI lesions or relapses as trial levelsurrogate outcomes for disability. We build on this work by developing a Bayesian three-level model,accommodating the two surrogates and the disability endpoint, and properly taking into account thattreatment effects are estimated with errors. Specifically, a combination of treatment effects based onMRI lesion count outcomes and clinical…

Subjects/Keywords: Statistics; Design of Experiment; Surrogate Outcomes

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APA (6^th Edition):

Pozzi, L. (2014). Topics in Evidence Synthesis. (Thesis). University of California – Berkeley. Retrieved from http://www.escholarship.org/uc/item/1b61431k

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Pozzi, Luca. “Topics in Evidence Synthesis.” 2014. Thesis, University of California – Berkeley. Accessed January 28, 2021. http://www.escholarship.org/uc/item/1b61431k.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Pozzi, Luca. “Topics in Evidence Synthesis.” 2014. Web. 28 Jan 2021.

Vancouver:

Pozzi L. Topics in Evidence Synthesis. [Internet] [Thesis]. University of California – Berkeley; 2014. [cited 2021 Jan 28]. Available from: http://www.escholarship.org/uc/item/1b61431k.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Pozzi L. Topics in Evidence Synthesis. [Thesis]. University of California – Berkeley; 2014. Available from: http://www.escholarship.org/uc/item/1b61431k

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Mississippi State University

16. Gandikota, Imtiaz Shareef. Multilevel design optimization of automotive structures using dummy- and vehicle-based responses.

Degree: MS, Aerospace Engineering, 2013, Mississippi State University

URL: http://sun.library.msstate.edu/ETD-db/theses/available/etd-07082013-123424/ ;

► A computationally efficient multilevel decomposition and optimization framework is developed for application to automotive structures. A full scale finite element (FE) model of a… (more)

Subjects/Keywords: crashworthiness; optimization; surrogate models; occupant restraint system

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APA (6^th Edition):

Gandikota, I. S. (2013). Multilevel design optimization of automotive structures using dummy- and vehicle-based responses. (Masters Thesis). Mississippi State University. Retrieved from http://sun.library.msstate.edu/ETD-db/theses/available/etd-07082013-123424/ ;

Chicago Manual of Style (16^th Edition):

Gandikota, Imtiaz Shareef. “Multilevel design optimization of automotive structures using dummy- and vehicle-based responses.” 2013. Masters Thesis, Mississippi State University. Accessed January 28, 2021. http://sun.library.msstate.edu/ETD-db/theses/available/etd-07082013-123424/ ;.

MLA Handbook (7^th Edition):

Gandikota, Imtiaz Shareef. “Multilevel design optimization of automotive structures using dummy- and vehicle-based responses.” 2013. Web. 28 Jan 2021.

Vancouver:

Gandikota IS. Multilevel design optimization of automotive structures using dummy- and vehicle-based responses. [Internet] [Masters thesis]. Mississippi State University; 2013. [cited 2021 Jan 28]. Available from: http://sun.library.msstate.edu/ETD-db/theses/available/etd-07082013-123424/ ;.

Council of Science Editors:

Gandikota IS. Multilevel design optimization of automotive structures using dummy- and vehicle-based responses. [Masters Thesis]. Mississippi State University; 2013. Available from: http://sun.library.msstate.edu/ETD-db/theses/available/etd-07082013-123424/ ;

Cornell University

17. Kristensen, Jesper. Uncertainty Quantification With Surrogate Models In Alloy Modeling.

Degree: PhD, Applied Physics, 2015, Cornell University

URL: http://hdl.handle.net/1813/40658

► The success of computational materials science in designing the materials of the future relies on the computation of materials properties using temporally expensive computer codes.… (more)

▼ The success of computational materials science in designing the materials of the future relies on the computation of materials properties using temporally expensive computer codes. Surrogate models, or simply surrogates, are employed to approximate the computer code and simultaneously decrease the computational effort by orders of magnitude enabling characterization, optimization, and design of materials in silico. To learn a surrogate, a few observations must be obtained from the expensive code, but once learned, the surrogate can predict the computer code output for any input. In most cases, one is faced with the task of choosing a narrow subset of best candidates among a larger set of potential surrogates for a given task. In this thesis, we present two new methods which improve surrogate modeling, and a third method capable of quantifying the uncertainty in materials properties predicted from the approximating surrogate. Our methods are general, but will be applied to the subset of materials called alloys. We start out by applying information theory to improve thermodynamic characterization of materials using surrogates. We explore employing relative entropy to measure "distance" between Boltzmann distributions, and find that our approach greatly improves current thermodynamic characterization in much better agreement with experiments. Then, we provide a rigorous way to propagate the uncertainty from not know- ing the best surrogate candidate to use and from having observed only a limited number of computer code observations during the process of lining up a set of relevant candidates. We show that the surrogate indeed captures properties to a satisfactory degree, as has been tacitly assumed so far in the field, with a predictive variance on the order of 5-10 %, which can be further improved if needed. Finally, we consider a materials design problem using surrogates. We consider the task of minimizing the thermal conductivity in nanowires. The low symmetry of these wires motivates us to introduce a modification to the traditional surrogate model employed to learn the property of such systems. We call the new technique the cluster expansion ghost lattice method and show how the method successfully predicts the nanowire structure with lowest thermal conductivity. Advisors/Committee Members: Kusse,Bruce Raymond (chair), Zabaras,Nicholas John (committee member), Hennig,Richard G. (committee member).

Subjects/Keywords: Uncertainty quantification; Surrogate models; Bayesian probability theory

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APA (6^th Edition):

Kristensen, J. (2015). Uncertainty Quantification With Surrogate Models In Alloy Modeling. (Doctoral Dissertation). Cornell University. Retrieved from http://hdl.handle.net/1813/40658

Chicago Manual of Style (16^th Edition):

Kristensen, Jesper. “Uncertainty Quantification With Surrogate Models In Alloy Modeling.” 2015. Doctoral Dissertation, Cornell University. Accessed January 28, 2021. http://hdl.handle.net/1813/40658.

MLA Handbook (7^th Edition):

Kristensen, Jesper. “Uncertainty Quantification With Surrogate Models In Alloy Modeling.” 2015. Web. 28 Jan 2021.

Vancouver:

Kristensen J. Uncertainty Quantification With Surrogate Models In Alloy Modeling. [Internet] [Doctoral dissertation]. Cornell University; 2015. [cited 2021 Jan 28]. Available from: http://hdl.handle.net/1813/40658.

Council of Science Editors:

Kristensen J. Uncertainty Quantification With Surrogate Models In Alloy Modeling. [Doctoral Dissertation]. Cornell University; 2015. Available from: http://hdl.handle.net/1813/40658

Cornell University

18. Liu, Yu-Cheng. Droplet Combustion Of Surrogate And Real Fuel Systems In A Low Convection Condition: Ground-Based And Space-Based Experiments.

Degree: PhD, Mechanical Engineering, 2013, Cornell University

URL: http://hdl.handle.net/1813/34387

► The droplet burning characteristics of aviation (Jet-A) and ground transportation (gasoline) fuels, a standard reference gasoline (indolene), three and four component surrogate fuels, several biodiesel… (more)

▼ The droplet burning characteristics of aviation (Jet-A) and ground transportation (gasoline) fuels, a standard reference gasoline (indolene), three and four component surrogate fuels, several biodiesel surrogates (methyl butanoate (MB) and decanoate (MD)), and three single component fuels (heptane, octane and decane) were examined from the perspective of the spherically symmetric droplet flame promoted by a low gravity environment in the standard atmosphere. The parameters included the initial droplet diameter (Do) and the fuel composition. Access to the experimental times required to observe the complete droplet burning history was obtained by carrying out the experiments in a drop tower that provided about 1 s of experimental time (Do < ~ 1 mm), and the orbiting International Space Station (ISS) using an experimental design on the ISS that could produce both freely-floating and fiber-supported droplets with essentially any Do and unlimited experimental times. For some of the results reported (those for n-heptane, n-octane, ndecane) Do was varied over the widest range ever reported (0.5 mm to 5 mm) across which radiative and sooting processes were considered to either influence burning (for Do > ~ 1.5 mm) or have a minimal affect (for Do < ~ 1 mm). For the other fuel systems investigated, Do was fixed at between 0.5 mm and 0.6 mm. Also discussed is a new imaging analysis method to automate data extraction from digital video records of the droplet burning history. The results showed the following: indolene droplets replicated reasonably well gasoline droplet burning; the three and four component blends examined performed closely to Jet-A; n-heptane and iso-octane mixture droplets did not replicate the burning characteristics of gasoline unless toluene was added to the mixture; the droplet burning rate decreases through the range of Do examined that spanned the ground-based and ISS data; and the ground based facility for studying fiber-supported droplet burning replicates quite well the burning characteristics of free-floating droplets of the same size and method of ignition. The value of the spherical droplet flame as a canonical liquid fuel burning configuration is shown for the complex fuel systems investigated. Advisors/Committee Members: Avedisian, C Thomas (chair), Zhang, Ke (committee member), Steen, Paul Herman (committee member).

Subjects/Keywords: droplet combustion; surrogate and biofuels; spherical symmetry

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APA (6^th Edition):

Liu, Y. (2013). Droplet Combustion Of Surrogate And Real Fuel Systems In A Low Convection Condition: Ground-Based And Space-Based Experiments. (Doctoral Dissertation). Cornell University. Retrieved from http://hdl.handle.net/1813/34387

Chicago Manual of Style (16^th Edition):

Liu, Yu-Cheng. “Droplet Combustion Of Surrogate And Real Fuel Systems In A Low Convection Condition: Ground-Based And Space-Based Experiments.” 2013. Doctoral Dissertation, Cornell University. Accessed January 28, 2021. http://hdl.handle.net/1813/34387.

MLA Handbook (7^th Edition):

Liu, Yu-Cheng. “Droplet Combustion Of Surrogate And Real Fuel Systems In A Low Convection Condition: Ground-Based And Space-Based Experiments.” 2013. Web. 28 Jan 2021.

Vancouver:

Liu Y. Droplet Combustion Of Surrogate And Real Fuel Systems In A Low Convection Condition: Ground-Based And Space-Based Experiments. [Internet] [Doctoral dissertation]. Cornell University; 2013. [cited 2021 Jan 28]. Available from: http://hdl.handle.net/1813/34387.

Council of Science Editors:

Liu Y. Droplet Combustion Of Surrogate And Real Fuel Systems In A Low Convection Condition: Ground-Based And Space-Based Experiments. [Doctoral Dissertation]. Cornell University; 2013. Available from: http://hdl.handle.net/1813/34387

Penn State University

19. Birriel, Barbara A. Surrogate Decision-Making in the Context of Critical Illness.

Degree: 2017, Penn State University

URL: https://submit-etda.libraries.psu.edu/catalog/13916bab44

► Purpose: The purpose of this study was to explore the process of surrogate decision-making during critical illness. The specific aims of the study were to… (more)

▼ Purpose: The purpose of this study was to explore the process of surrogate decision-making during critical illness. The specific aims of the study were to describe the process of surrogate decision-making for critically ill adult patients, including surrogate decision-makers’ cognitive and moral decision-making processes and to develop a model explaining the process. Background: Critically ill patients are often unable to make independent decisions about their health care, requiring a family member to serve as surrogate decision-maker. Decisions made by surrogates affect not only their individual situations, but have implications for the health care system and society as a whole. The majority of work on surrogate decision-making has been related to chronic or slow progressing illness but little is known about the experiences of surrogate decision-makers during critical illness. Methods: A prospective qualitative approach was used based in grounded theory. The setting included four intensive care units (ICUs) in a large university medical center. The sample consisted of 19 surrogate decision-makers (as identified on patient record) of critically ill patients in the acute phase of critical illness who were unable to make independent health care decisions. Participants were interviewed on enrollment and 14 days later, or at the time the patient for whom they were making decisions was transferred from the ICU if sooner than 14 days. The interviews explored participants’ cognitive and moral decision-making processes. An interview guide framed the interviews, though participants were encouraged to speak freely. Data analysis was completed per the tenets of grounded theory, beginning with the first interview and concluding when data saturation was achieved. Results: A model of the Process of Surrogate Decision-Making in Critical Illness was developed, grounded in the data, to explain the process of surrogate decision-making in the context of acute critical illness. Four major themes emerged from the data and are included in the model: Understanding the Patient’s Values and Preferences, Acquiring Health Care Knowledge, Considering Family Perspectives, and Recognizing Personal Values. The overarching theme that explains the connections between the themes is Integration. Conclusions: The findings of this study bring a new perspective to surrogate decision-making during critical illness, intertwining the cognitive and moral processes. Through integration of the four identified themes, the surrogate decision-maker reaches decisions based on a broader understanding of the factors involved. Nurses are well positioned to assist surrogates through this process during the critical illness of a family member. The model of the Process of Surrogate Decision-Making in Critical Illness forms a basis for education of nurses and other healthcare providers and the development of intervention studies to optimize the results of the surrogate decision-making process. Advisors/Committee Members: Lisa Kitko, Dissertation Advisor/Co-Advisor, Lisa Kitko, Committee Chair/Co-Chair, Judith Hupcey, Committee Member, Susan Loeb, Committee Member, Michelle McGowan, Outside Member.

Subjects/Keywords: Surrogate decision-making; critical care; bioethics; ethics

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APA (6^th Edition):

Birriel, B. A. (2017). Surrogate Decision-Making in the Context of Critical Illness. (Thesis). Penn State University. Retrieved from https://submit-etda.libraries.psu.edu/catalog/13916bab44

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Birriel, Barbara A. “Surrogate Decision-Making in the Context of Critical Illness.” 2017. Thesis, Penn State University. Accessed January 28, 2021. https://submit-etda.libraries.psu.edu/catalog/13916bab44.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Birriel, Barbara A. “Surrogate Decision-Making in the Context of Critical Illness.” 2017. Web. 28 Jan 2021.

Vancouver:

Birriel BA. Surrogate Decision-Making in the Context of Critical Illness. [Internet] [Thesis]. Penn State University; 2017. [cited 2021 Jan 28]. Available from: https://submit-etda.libraries.psu.edu/catalog/13916bab44.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Birriel BA. Surrogate Decision-Making in the Context of Critical Illness. [Thesis]. Penn State University; 2017. Available from: https://submit-etda.libraries.psu.edu/catalog/13916bab44

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Toronto

20. Mawyin, Tomas. Sensitivity Analysis of Material Property Predictions in Molecular Dynamics with Interatomic Potentials under Uncertainty.

Degree: 2015, University of Toronto

URL: http://hdl.handle.net/1807/70456

►

Molecular Dynamics (MD) simulations complement experimental methods by offering a computationally fast and accurate framework for determining the properties of materials. However, there is uncertainty… (more)

Subjects/Keywords: Aluminium; Graphene; Molecular Dynamics; Surrogate Models; 0538

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APA (6^th Edition):

Mawyin, T. (2015). Sensitivity Analysis of Material Property Predictions in Molecular Dynamics with Interatomic Potentials under Uncertainty. (Masters Thesis). University of Toronto. Retrieved from http://hdl.handle.net/1807/70456

Chicago Manual of Style (16^th Edition):

Mawyin, Tomas. “Sensitivity Analysis of Material Property Predictions in Molecular Dynamics with Interatomic Potentials under Uncertainty.” 2015. Masters Thesis, University of Toronto. Accessed January 28, 2021. http://hdl.handle.net/1807/70456.

MLA Handbook (7^th Edition):

Mawyin, Tomas. “Sensitivity Analysis of Material Property Predictions in Molecular Dynamics with Interatomic Potentials under Uncertainty.” 2015. Web. 28 Jan 2021.

Vancouver:

Mawyin T. Sensitivity Analysis of Material Property Predictions in Molecular Dynamics with Interatomic Potentials under Uncertainty. [Internet] [Masters thesis]. University of Toronto; 2015. [cited 2021 Jan 28]. Available from: http://hdl.handle.net/1807/70456.

Council of Science Editors:

Mawyin T. Sensitivity Analysis of Material Property Predictions in Molecular Dynamics with Interatomic Potentials under Uncertainty. [Masters Thesis]. University of Toronto; 2015. Available from: http://hdl.handle.net/1807/70456

University of the Western Cape

21. Rispel, Shane-Leane. The scope and content of the child's right to identidy in the context of surrogacy .

Degree: 2017, University of the Western Cape

URL: http://hdl.handle.net/11394/5703

► The development of assisted reproductive technology (ART) has radically changed the landscape of the conventional family. It has permitted a platform for the creation of… (more)

Subjects/Keywords: Right to identity; Surrogacy; Surrogate; Child rights

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APA (6^th Edition):

Rispel, S. (2017). The scope and content of the child's right to identidy in the context of surrogacy . (Thesis). University of the Western Cape. Retrieved from http://hdl.handle.net/11394/5703

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Rispel, Shane-Leane. “The scope and content of the child's right to identidy in the context of surrogacy .” 2017. Thesis, University of the Western Cape. Accessed January 28, 2021. http://hdl.handle.net/11394/5703.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Rispel, Shane-Leane. “The scope and content of the child's right to identidy in the context of surrogacy .” 2017. Web. 28 Jan 2021.

Vancouver:

Rispel S. The scope and content of the child's right to identidy in the context of surrogacy . [Internet] [Thesis]. University of the Western Cape; 2017. [cited 2021 Jan 28]. Available from: http://hdl.handle.net/11394/5703.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Rispel S. The scope and content of the child's right to identidy in the context of surrogacy . [Thesis]. University of the Western Cape; 2017. Available from: http://hdl.handle.net/11394/5703

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Newcastle upon Tyne

22. Haimes, Erica Victoria. Family connections : the management of biological origins in the new reproductive technologies.

Degree: PhD, 1990, University of Newcastle upon Tyne

URL: http://theses.ncl.ac.uk/jspui/handle/10443/281 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.278742

► This thesis investigates the management of information about the biological origins of individuals conceived through the use of a third party; that is, by donated… (more)

Subjects/Keywords: 362.1; Surrogate children

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APA (6^th Edition):

Haimes, E. V. (1990). Family connections : the management of biological origins in the new reproductive technologies. (Doctoral Dissertation). University of Newcastle upon Tyne. Retrieved from http://theses.ncl.ac.uk/jspui/handle/10443/281 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.278742

Chicago Manual of Style (16^th Edition):

Haimes, Erica Victoria. “Family connections : the management of biological origins in the new reproductive technologies.” 1990. Doctoral Dissertation, University of Newcastle upon Tyne. Accessed January 28, 2021. http://theses.ncl.ac.uk/jspui/handle/10443/281 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.278742.

MLA Handbook (7^th Edition):

Haimes, Erica Victoria. “Family connections : the management of biological origins in the new reproductive technologies.” 1990. Web. 28 Jan 2021.

Vancouver:

Haimes EV. Family connections : the management of biological origins in the new reproductive technologies. [Internet] [Doctoral dissertation]. University of Newcastle upon Tyne; 1990. [cited 2021 Jan 28]. Available from: http://theses.ncl.ac.uk/jspui/handle/10443/281 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.278742.

Council of Science Editors:

Haimes EV. Family connections : the management of biological origins in the new reproductive technologies. [Doctoral Dissertation]. University of Newcastle upon Tyne; 1990. Available from: http://theses.ncl.ac.uk/jspui/handle/10443/281 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.278742

University of Edinburgh

23. Ensor, Hannah Margaret. Statistical evaluation of surrogate outcomes : methodological extensions to ordinal outcomes with applications in acute stroke.

Degree: PhD, 2016, University of Edinburgh

URL: http://hdl.handle.net/1842/22931

► Background Surrogate outcomes are measures of treatment effect that can be used to predict treatment effect on the true outcome of interest. Surrogates are valued… (more)

▼ Background Surrogate outcomes are measures of treatment effect that can be used to predict treatment effect on the true outcome of interest. Surrogates are valued as they can be used in place of true outcomes to reduce the length, size, or intrusiveness of a clinical trial. However, validation of surrogacy is a conceptually complicated area and much theoretical and practical statistical development has been conducted in recent years. Methods A systematic review was conducted to identify which surrogate evaluation approach was best suited to be extended to ordinal outcomes. I extended a foremost approach to the case where the surrogate, the true clinical outcome, or both are ordinal outcomes. This extension investigated surrogacy at both the trial and individual levels; trial level surrogacy was based on a two stage method. The extension was developed through large simulation studies and used to investigate whether deep venous thromboembolism (DVT) was a surrogate for the ongoing measure of death and disability the Oxford Handicap Scale (OHS), using data from the stroke trial CLOTS3. CLOTS3 was a large multi-centre randomised clinical trial which investigated whether intermittent pneumatic compression (IPC) applied to the legs reduced the occurrence of deep venous thromboembolism (DVT) in stroke clinical trial patients. Results The systematic review identified the information theory approach as the most intuitively and practically worthwhile approach to surrogacy evaluation. I extended this approach to: a binary surrogate and ordinal true outcome (the binary-ordinal setting); the ordinal-binary and the ordinal-ordinal settings. The simulation studies showed that the approach worked well in most scenarios tested. However, trial level surrogacy was impacted by loss of efficiency due to the use of the two stage method. Bias imposed at the trial level by separation of discrete outcomes was effectively dealt with using a penalised likelihood method. The information theory approach for ordinal outcomes identified no surrogate that would predict treatment effect of IPC on the true outcome OHS measured at six months in the stroke trial CLOTS3.

Subjects/Keywords: 616.8; surrogate; clinical trials; methodology; ordinal

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APA (6^th Edition):

Ensor, H. M. (2016). Statistical evaluation of surrogate outcomes : methodological extensions to ordinal outcomes with applications in acute stroke. (Doctoral Dissertation). University of Edinburgh. Retrieved from http://hdl.handle.net/1842/22931

Chicago Manual of Style (16^th Edition):

Ensor, Hannah Margaret. “Statistical evaluation of surrogate outcomes : methodological extensions to ordinal outcomes with applications in acute stroke.” 2016. Doctoral Dissertation, University of Edinburgh. Accessed January 28, 2021. http://hdl.handle.net/1842/22931.

MLA Handbook (7^th Edition):

Ensor, Hannah Margaret. “Statistical evaluation of surrogate outcomes : methodological extensions to ordinal outcomes with applications in acute stroke.” 2016. Web. 28 Jan 2021.

Vancouver:

Ensor HM. Statistical evaluation of surrogate outcomes : methodological extensions to ordinal outcomes with applications in acute stroke. [Internet] [Doctoral dissertation]. University of Edinburgh; 2016. [cited 2021 Jan 28]. Available from: http://hdl.handle.net/1842/22931.

Council of Science Editors:

Ensor HM. Statistical evaluation of surrogate outcomes : methodological extensions to ordinal outcomes with applications in acute stroke. [Doctoral Dissertation]. University of Edinburgh; 2016. Available from: http://hdl.handle.net/1842/22931

24. Bradbury, Mark. Genomic and flow cytometric studies of Clostridium sporogenes, a non-toxigenic surrogate for Clostridium botulinum.

Degree: PhD, 2014, Federation University Australia

URL: http://researchonline.federation.edu.au/vital/access/HandleResolver/1959.17/97216 ; https://library.federation.edu.au/record=b2633659~S4

►

Clostridium sporogenes and Group I Clostridium botulinum are two bacterial species belonging to the same phylogenetic group, primarily differentiated by the expression of botulinum neurotoxin.… (more)

▼

Clostridium sporogenes and Group I Clostridium botulinum are two bacterial species belonging to the same phylogenetic group, primarily differentiated by the expression of botulinum neurotoxin. Both organisms are of significant commercial importance in regards to the spoilage of and/or disease in thermally processed food products due to their ability to form heat resistant spores. As such, these species are often used as the target organism for the design of thermal inactivation processes, particularly in regards to thermal sterilisation. Two specific aspects pertaining to these organisms were investigated to further enhance knowledge with respect to their use in thermal processing studies: the genetic relationship between C. sporogenes and Group I C. botulinum; and the mechanism of heat resistance in spores of C. sporogenes. The first part of this thesis describes the assembly, annotation and analysis of the draft genome of C. sporogenes PA 3679 (the most widely used surrogate for Group I C. botulinum). These data allowed identification of unique variants genes related to spore germination, analogous toxin regions and mobile elements between species. MLST analysis revealed that phylogeny was an ineffective indicator of toxigenicity in this group and thus prompted a pan-genomic analysis. The pan-genome of C. sporogenes/Group I C. botulinum was found to consist of 8799 coding sequences (CDS’s) and a core genome consisting of 1590 CDS’s. Analysis of this pan-genome revealed the significant role that mobile genetic elements have played in genetic diversity within this group of organisms. The second part of this thesis investigated the heat inactivation of C. sporogenes PA 3679 spores in regards to structural variation and population heterogeneity. A novel flow cytometric approach was developed and utilised to investigate isothermal spore inactivation; and implications of the impact of NaCl on the intrinsic variability throughout this process and during a subsequent recovery period. Based on these approaches a possible mechanistic description for the thermal inactivation of spores was developed. Together, these studies present significant evidence supporting the continued suitability of C. sporogenes as a surrogate for Group I C. botulinum, whilst also enhancing the understanding of clostridial spore inactivation during a moist heat process.

Doctor of Philosophy

Subjects/Keywords: Clostridium sporogenes; Non-toxigenic surrogate; Clostridium botulinum

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APA (6^th Edition):

Bradbury, M. (2014). Genomic and flow cytometric studies of Clostridium sporogenes, a non-toxigenic surrogate for Clostridium botulinum. (Doctoral Dissertation). Federation University Australia. Retrieved from http://researchonline.federation.edu.au/vital/access/HandleResolver/1959.17/97216 ; https://library.federation.edu.au/record=b2633659~S4

Chicago Manual of Style (16^th Edition):

Bradbury, Mark. “Genomic and flow cytometric studies of Clostridium sporogenes, a non-toxigenic surrogate for Clostridium botulinum.” 2014. Doctoral Dissertation, Federation University Australia. Accessed January 28, 2021. http://researchonline.federation.edu.au/vital/access/HandleResolver/1959.17/97216 ; https://library.federation.edu.au/record=b2633659~S4.

MLA Handbook (7^th Edition):

Bradbury, Mark. “Genomic and flow cytometric studies of Clostridium sporogenes, a non-toxigenic surrogate for Clostridium botulinum.” 2014. Web. 28 Jan 2021.

Vancouver:

Bradbury M. Genomic and flow cytometric studies of Clostridium sporogenes, a non-toxigenic surrogate for Clostridium botulinum. [Internet] [Doctoral dissertation]. Federation University Australia; 2014. [cited 2021 Jan 28]. Available from: http://researchonline.federation.edu.au/vital/access/HandleResolver/1959.17/97216 ; https://library.federation.edu.au/record=b2633659~S4.

Council of Science Editors:

Bradbury M. Genomic and flow cytometric studies of Clostridium sporogenes, a non-toxigenic surrogate for Clostridium botulinum. [Doctoral Dissertation]. Federation University Australia; 2014. Available from: http://researchonline.federation.edu.au/vital/access/HandleResolver/1959.17/97216 ; https://library.federation.edu.au/record=b2633659~S4

Delft University of Technology

25. Li, Ang (author). Optimization of Composite Structures for Crashworthiness.

Degree: 2019, Delft University of Technology

URL: http://resolver.tudelft.nl/uuid:66aaf067-8763-4c39-91e3-ef01fb25948d

►

Structural optimization for crashworthiness in composite structures has become an important topic of research in aerospace, attributable to its proven benefits to the occupants' safety… (more)

▼

Structural optimization for crashworthiness in composite structures has become an important topic of research in aerospace, attributable to its proven benefits to the occupants' safety in an aircraft during a crash event. This thesis provides a comprehensive investigation on LS-DYNA modeling and design optimization of composite square tubes for crashworthiness. The objective of this thesis is to construct a optimization framework specialized for the preliminary design of composite structures with a balance of performance and efficiency. Three primary components are involved: firstly, coupon-level simulations in LS-DYNA are performed to characterize the material properties for carbon/epoxy composite material IM7/8552; secondly, a square tube is modeled by a single-layer approach in three mainstream material cards (MAT-54, MAT-58 and MAT-262) with calibrated parameters for crush simulation in LS-DYNA. Meanwhile, detailed sensitivity analysis of influential parameters in different material models is also be performed to have a more comprehensive understanding of the complex failure mechanism. The simulation results indicate good correlation to the experiments in terms of energy absorption and maximum peak load, with high computational efficiency and low-cost calibration. Lastly, a two-stage single-objective optimization is performed, which incorporates the fiber orientation for each layer as design variables and design/manufacturing rules as constraints. Two surrogate models are created to formulate the mapping between input design variables and output crashworthiness metrics, including Deep Neural Networks (DNN) and Gradient Boosting Regression Trees (GBRT) ensemble. Followed by Mix-Discrete Particle Swarm Optimization (MDPSO) algorithm, the optimal set of design variables are obtained for each surrogate model. The first-stage optimization results demonstrate significant improvement in the crashworthiness performance compared with the baseline value, while the second-stage optimization results indicate an excellent transferability of the proposed optimization framework. This applicable, transferable, and data-driven optimization framework can be used in the aerospace industry regarding the crashworthy design and optimization of composite structures.

Aerospace Engineering

Advisors/Committee Members: Bisagni, Chiara (mentor), Delft University of Technology (degree granting institution).

Subjects/Keywords: Optimization; Crashworthiness; Surrogate models; LS-DYNA

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APA (6^th Edition):

Li, A. (. (2019). Optimization of Composite Structures for Crashworthiness. (Masters Thesis). Delft University of Technology. Retrieved from http://resolver.tudelft.nl/uuid:66aaf067-8763-4c39-91e3-ef01fb25948d

Chicago Manual of Style (16^th Edition):

Li, Ang (author). “Optimization of Composite Structures for Crashworthiness.” 2019. Masters Thesis, Delft University of Technology. Accessed January 28, 2021. http://resolver.tudelft.nl/uuid:66aaf067-8763-4c39-91e3-ef01fb25948d.

MLA Handbook (7^th Edition):

Li, Ang (author). “Optimization of Composite Structures for Crashworthiness.” 2019. Web. 28 Jan 2021.

Vancouver:

Li A(. Optimization of Composite Structures for Crashworthiness. [Internet] [Masters thesis]. Delft University of Technology; 2019. [cited 2021 Jan 28]. Available from: http://resolver.tudelft.nl/uuid:66aaf067-8763-4c39-91e3-ef01fb25948d.

Council of Science Editors:

Li A(. Optimization of Composite Structures for Crashworthiness. [Masters Thesis]. Delft University of Technology; 2019. Available from: http://resolver.tudelft.nl/uuid:66aaf067-8763-4c39-91e3-ef01fb25948d

26. Goodwiller, Bradley. Investigating the Use of Passive Acoustics as a Surrogate Method of Monitoring Coarse Bedload Transport in Rivers and Streams via Laboratory Experiments and Field Studies.

Degree: PhD, Civil Engineering, 2019, University of Mississippi

URL: https://egrove.olemiss.edu/etd/1614

► The movement of coarse gravel in rivers in streams is important for many applications including wildlife habitation, river morphology, infrastructure maintenance and marine navigation. Physical… (more)

Subjects/Keywords: Acoustic Surrogate; Bedload transport; Civil Engineering

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APA (6^th Edition):

Goodwiller, B. (2019). Investigating the Use of Passive Acoustics as a Surrogate Method of Monitoring Coarse Bedload Transport in Rivers and Streams via Laboratory Experiments and Field Studies. (Doctoral Dissertation). University of Mississippi. Retrieved from https://egrove.olemiss.edu/etd/1614

Chicago Manual of Style (16^th Edition):

Goodwiller, Bradley. “Investigating the Use of Passive Acoustics as a Surrogate Method of Monitoring Coarse Bedload Transport in Rivers and Streams via Laboratory Experiments and Field Studies.” 2019. Doctoral Dissertation, University of Mississippi. Accessed January 28, 2021. https://egrove.olemiss.edu/etd/1614.

MLA Handbook (7^th Edition):

Goodwiller, Bradley. “Investigating the Use of Passive Acoustics as a Surrogate Method of Monitoring Coarse Bedload Transport in Rivers and Streams via Laboratory Experiments and Field Studies.” 2019. Web. 28 Jan 2021.

Vancouver:

Goodwiller B. Investigating the Use of Passive Acoustics as a Surrogate Method of Monitoring Coarse Bedload Transport in Rivers and Streams via Laboratory Experiments and Field Studies. [Internet] [Doctoral dissertation]. University of Mississippi; 2019. [cited 2021 Jan 28]. Available from: https://egrove.olemiss.edu/etd/1614.

Council of Science Editors:

Goodwiller B. Investigating the Use of Passive Acoustics as a Surrogate Method of Monitoring Coarse Bedload Transport in Rivers and Streams via Laboratory Experiments and Field Studies. [Doctoral Dissertation]. University of Mississippi; 2019. Available from: https://egrove.olemiss.edu/etd/1614

27. Bhatta, Dilli. A Bayesian Test of Independence for Two-way Contingency Tables Under Cluster Sampling.

Degree: PhD, 2013, Worcester Polytechnic Institute

URL: etd-041913-131023 ; https://digitalcommons.wpi.edu/etd-dissertations/128

► We consider a Bayesian approach to the study of independence in a two-way contingency table obtained from a two-stage cluster sampling design. We study the… (more)

▼ We consider a Bayesian approach to the study of independence in a two-way contingency table obtained from a two-stage cluster sampling design. We study the association between two categorical variables when (a) there are no covariates and (b) there are covariates at both unit and cluster levels. Our main idea for the Bayesian test of independence is to convert the cluster sample into an equivalent simple random sample which provides a surrogate of the original sample. Then, this surrogate sample is used to compute the Bayes factor to make an inference about independence. For the test of independence without covariates, the Rao-Scott corrections to the standard chi-squared (or likelihood ratio) statistic were developed. They are ``large sample' methods and provide appropriate inference when there are large cell counts. However, they are less successful when there are small cell counts. We have developed the methodology to overcome the limitations of Rao-Scott correction. We have used a hierarchical Bayesian model to convert the observed cluster samples to simple random samples. This provides the surrogate samples which can be used to derive the distribution of the Bayes factor to make an inference about independence. We have used a sampling-based method to fit the model. For the test of independence with covariates, we first convert the cluster sample with covariates to a cluster sample without covariates. We use multinomial logistic regression model with random effects to accommodate the cluster effects. Our idea is to fit the cluster samples to the random effect models and predict the new samples by adjusting with the covariates. This provides the cluster sample without covariates. We then use a hierarchical Bayesian model to convert this cluster sample to a simple random sample which allows us to calculate the Bayes factor to make an inference about independence. We use Markov chain Monte Carlo methods to fit our models. We apply our first method to the Third International Mathematics and Science Study (1995) for third grade U.S. students in which we study the association between the mathematics test scores and the communities the students come from, and science test scores and the communities the students come from. We also provide a simulation study which establishes our methodology as a viable alternative to the Rao-Scott approximations for relatively small two-stage cluster samples. We apply our second method to the data from the Trend in International Mathematics and Science Study (2007) for fourth grade U.S. students to assess the association between the mathematics and science scores represented as categorical variables and also provide the simulation study. The result shows that if there is strong association between two categorical variables, there is no difference between the significance of the test in using the model (a) with covariates and (b) without covariates. However, in simulation studies, there is a noticeable difference in the significance of the test between the two models when there are… Advisors/Committee Members: Jai Won Choi, Committee Member, Hasanjan Sayit, Committee Member, Balgobin Nandram, Advisor, Joe Sedransk, Committee Member, Dominique Haughton, Committee Member.

Subjects/Keywords: Surrogate samples; Bayes factor; Hierarchical Baye

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APA (6^th Edition):

Bhatta, D. (2013). A Bayesian Test of Independence for Two-way Contingency Tables Under Cluster Sampling. (Doctoral Dissertation). Worcester Polytechnic Institute. Retrieved from etd-041913-131023 ; https://digitalcommons.wpi.edu/etd-dissertations/128

Chicago Manual of Style (16^th Edition):

Bhatta, Dilli. “A Bayesian Test of Independence for Two-way Contingency Tables Under Cluster Sampling.” 2013. Doctoral Dissertation, Worcester Polytechnic Institute. Accessed January 28, 2021. etd-041913-131023 ; https://digitalcommons.wpi.edu/etd-dissertations/128.

MLA Handbook (7^th Edition):

Bhatta, Dilli. “A Bayesian Test of Independence for Two-way Contingency Tables Under Cluster Sampling.” 2013. Web. 28 Jan 2021.

Vancouver:

Bhatta D. A Bayesian Test of Independence for Two-way Contingency Tables Under Cluster Sampling. [Internet] [Doctoral dissertation]. Worcester Polytechnic Institute; 2013. [cited 2021 Jan 28]. Available from: etd-041913-131023 ; https://digitalcommons.wpi.edu/etd-dissertations/128.

Council of Science Editors:

Bhatta D. A Bayesian Test of Independence for Two-way Contingency Tables Under Cluster Sampling. [Doctoral Dissertation]. Worcester Polytechnic Institute; 2013. Available from: etd-041913-131023 ; https://digitalcommons.wpi.edu/etd-dissertations/128

University of Tennessee – Knoxville

28. Francis, Eric James. CHARACTERIZATION OF AN ARGON-HYDROGEN PLASMA TORCH FOR PRODUCTION OF SURROGATE NUCLEAR MELT GLASS.

Degree: MS, Nuclear Engineering, 2018, University of Tennessee – Knoxville

URL: https://trace.tennessee.edu/utk_gradthes/5099

► Extensive research has been conducted to characterize trinitite to glean information about the physics associated with a nuclear blast. This information is particularly important to… (more)

Subjects/Keywords: Spectroscopy; Surrogate Melt Glass; Plasma Characterization

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APA (6^th Edition):

Francis, E. J. (2018). CHARACTERIZATION OF AN ARGON-HYDROGEN PLASMA TORCH FOR PRODUCTION OF SURROGATE NUCLEAR MELT GLASS. (Thesis). University of Tennessee – Knoxville. Retrieved from https://trace.tennessee.edu/utk_gradthes/5099

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Francis, Eric James. “CHARACTERIZATION OF AN ARGON-HYDROGEN PLASMA TORCH FOR PRODUCTION OF SURROGATE NUCLEAR MELT GLASS.” 2018. Thesis, University of Tennessee – Knoxville. Accessed January 28, 2021. https://trace.tennessee.edu/utk_gradthes/5099.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Francis, Eric James. “CHARACTERIZATION OF AN ARGON-HYDROGEN PLASMA TORCH FOR PRODUCTION OF SURROGATE NUCLEAR MELT GLASS.” 2018. Web. 28 Jan 2021.

Vancouver:

Francis EJ. CHARACTERIZATION OF AN ARGON-HYDROGEN PLASMA TORCH FOR PRODUCTION OF SURROGATE NUCLEAR MELT GLASS. [Internet] [Thesis]. University of Tennessee – Knoxville; 2018. [cited 2021 Jan 28]. Available from: https://trace.tennessee.edu/utk_gradthes/5099.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Francis EJ. CHARACTERIZATION OF AN ARGON-HYDROGEN PLASMA TORCH FOR PRODUCTION OF SURROGATE NUCLEAR MELT GLASS. [Thesis]. University of Tennessee – Knoxville; 2018. Available from: https://trace.tennessee.edu/utk_gradthes/5099

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Georgia State University

29. Couch, Kelli. A thing among things.

Degree: MFA, Art and Design, 2018, Georgia State University

URL: https://scholarworks.gsu.edu/art_design_theses/234

► A thing among things is an endless pursuit to expand the definition of home and find resolve during life’s circumstances. I constantly search for… (more)

Subjects/Keywords: Photography; Staged; Happenstance; Surrogate; Fantasy; Self-mythology

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APA (6^th Edition):

Couch, K. (2018). A thing among things. (Thesis). Georgia State University. Retrieved from https://scholarworks.gsu.edu/art_design_theses/234

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Couch, Kelli. “A thing among things.” 2018. Thesis, Georgia State University. Accessed January 28, 2021. https://scholarworks.gsu.edu/art_design_theses/234.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Couch, Kelli. “A thing among things.” 2018. Web. 28 Jan 2021.

Vancouver:

Couch K. A thing among things. [Internet] [Thesis]. Georgia State University; 2018. [cited 2021 Jan 28]. Available from: https://scholarworks.gsu.edu/art_design_theses/234.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Couch K. A thing among things. [Thesis]. Georgia State University; 2018. Available from: https://scholarworks.gsu.edu/art_design_theses/234

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of New South Wales

30. Leylek, Zafer. Global Surrogate Modelling of Gas Turbine Aerodynamic Performance.

Degree: Engineering & Information Technology, 2018, University of New South Wales

URL: http://handle.unsw.edu.au/1959.4/60074 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:51324/SOURCE2?view=true

► The compressor and turbine aerodynamic performance of a gas turbine engine depends on complex three-dimensional unsteady interactions between static and rotating blades. Each component is… (more)

▼ The compressor and turbine aerodynamic performance of a gas turbine engine depends on complex three-dimensional unsteady interactions between static and rotating blades. Each component is made up of a series of rotor and stator blades, whose overall performance is dependent on blade geometry, manufacturing and operating conditions. This in turn leads to a large number of independent parameters which control compressor and turbine aerodynamic performance. Conducting high fidelity parametric analysis within such a large domain and constraint space is not feasible, even when using state-of-the-art computational resources.Surrogate modelling techniques have been widely used within the industry to overcome such complex, multi-dimensional analysis problems. That is, the compressor and turbine have been broken down to single blade stages, each blade stage and operating condition represented parametrically and surrogate models developed to predict performance of each stage. A basic surrogate model is then used to predict the performance of the compressor or turbine system.The surrogate models that are currently being used are based on limited experimental data and are open to interpretation. Also, they seem to reflect outdated technology and the construction and enhancement of these models based on experiment are very time consuming and costly.This research combines the latest Design and Analysis of Computer Experiment (DACE), Computational Fluid Dynamics (CFD) and surrogate modelling techniques to predict the performance of compressors and turbines. A number of different surrogate modelling techniques are evaluated and optimised for accuracy and efficiency. The surrogate models are further enhanced using parametric space exploration and subset regression analysis. The surrogate models are then validated with CFD generated compressor and turbine maps. Data mining or knowledge extraction studies are presented to mine the large number of simulations not only for prediction but also to gain an understanding of the underlying processes that drive compressor and turbine performance.Advances to the current state-of-the-art in a number of areas are also presented. The first is the development of a blade geometry mapping techniques that allows the use of DACE space filling designs to irregularly shaped design envelopes. The second is the development and refinement of adaptive sampling techniques using Gaussian process regression also known as Kriging.This research shows that it is possible to create accurate surrogate models of turbine blade aerodynamic performance for up to fifteen dimensions. Increasing the number of dimensions results in issues associated with the `curse-of-dimensionality'. Feature extraction and data mining techniques used in assessing the importance of blade performance parameters point to a similar weighting of the blade feature importance, however, the study also showed that it is not possible to eliminate lower ranked features without significantly degrading the surrogate model accuracy. Tackling the… Advisors/Committee Members: Neely, Andrew, UNSW.

Subjects/Keywords: Compressor; Turbine; Surrogate modelling; Aerodynamic performance

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APA (6^th Edition):

Leylek, Z. (2018). Global Surrogate Modelling of Gas Turbine Aerodynamic Performance. (Doctoral Dissertation). University of New South Wales. Retrieved from http://handle.unsw.edu.au/1959.4/60074 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:51324/SOURCE2?view=true

Chicago Manual of Style (16^th Edition):

Leylek, Zafer. “Global Surrogate Modelling of Gas Turbine Aerodynamic Performance.” 2018. Doctoral Dissertation, University of New South Wales. Accessed January 28, 2021. http://handle.unsw.edu.au/1959.4/60074 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:51324/SOURCE2?view=true.

MLA Handbook (7^th Edition):

Leylek, Zafer. “Global Surrogate Modelling of Gas Turbine Aerodynamic Performance.” 2018. Web. 28 Jan 2021.

Vancouver:

Leylek Z. Global Surrogate Modelling of Gas Turbine Aerodynamic Performance. [Internet] [Doctoral dissertation]. University of New South Wales; 2018. [cited 2021 Jan 28]. Available from: http://handle.unsw.edu.au/1959.4/60074 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:51324/SOURCE2?view=true.

Council of Science Editors:

Leylek Z. Global Surrogate Modelling of Gas Turbine Aerodynamic Performance. [Doctoral Dissertation]. University of New South Wales; 2018. Available from: http://handle.unsw.edu.au/1959.4/60074 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:51324/SOURCE2?view=true

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