subject:(smooth interaction)

1. 三橋, 里子. Blebbistatinによる気管平滑筋スキンド標本弛緩促進作用のメカニズム : Mechanisms of accelerating effect of blebbistatin on relaxation process of skinned tracheal smooth muscle.

Degree: 修士（健康科学）, 2017, Tokyo Metropolitan University / 首都大学東京

URL: http://hdl.handle.net/10748/00009633

►

[緒言] ミオシンII阻害薬であるblebbiststinは、平滑筋アクトミオシンATPase活性を10μM程度で抑制する。blebbistatinは平滑筋標本においては収縮のCa^<2+>感受性やミオシン軽鎖リン酸化レベルには影響は与えず、アクチン・ミオシン相互作用を直接抑制することにより、その収縮を抑制するといわれている。blebbistatinはミオシンATPase加水分解サイクルに伴うミオシンのアクチンへの結合・解離に影響を及ぼすことが考えられることから、弛緩過程におけるクロスブリッジの解離にも影響を与えることが推察される。そこで本研究では、細胞膜を化学的に破壊して気管平滑筋スキンド標本のCa^<2+>収縮後の弛緩過程とミオシンATPaseサイクルの影響を受けないrigor形成・解離に対するblebbistatinの効果を動力学的に検討した。[方法] モルモット気管平滑筋に100μMのβ-escinで処理をしてスキンド標本を作製し、圧トランスデューサーに取り付けて等尺性張力を測定した。Ca^<2+>による最大収縮の後、EGTAによりCa^<2+>を素早く除去して弛緩させ、同時にblebbistatinを添加し15分間計測した。また、Ca^<2+>収縮後のrigor状態におけるblebbistatinについても同様の方法で検討した。統計処理はt-testを使用しP＜0.05を有意水準とした。[結果] Ca^<2+>収縮後の弛緩過程において、気管平滑筋スキンド標本は30μM程度で弛緩過程を促進し、回帰分析の結果からラッチの解離を速めていた。一方、Ca^<2+>収縮後のrigor状態では相対張力において有意な弛緩はみられなかったが、回帰分析の結果、30μMでrigorの解離の抑制と収縮後一度外れたクロスブリッジがrigorに移行する割合がコントロール群と比較して少ない値を示した。[考察] Blebbistatinは、ATPやアクチンのミオシンへの結合を直接阻害するのではなく、ミオシン頭部構造変化に影響してアクチン・ミオシン結合を弱めることが知られている。ATPの有無によって、Ca^<2+>収縮で発生した収縮張力のCa^<2+>除去後の減衰過程に対するblebbistatinの影響が異なるのは、blebbistatinがミオシン頭部構造変化に与える効果はミオシン頭部へのATPの結合の有無によって変化することを強く示唆する。平滑筋細胞において無酸素状態における力学反応の実態は不明であるが、blebbistatinはその解明に向けて研究において有用なツールになると考えられる。

Blebbistatin, an inhibitor of myosin II , has an inhibitory effect on smooth muscle actomyosin ATPase activity at around 10μM.… (more)

▼

[緒言] ミオシンII阻害薬であるblebbiststinは、平滑筋アクトミオシンATPase活性を10μM程度で抑制する。blebbistatinは平滑筋標本においては収縮のCa^<2+>感受性やミオシン軽鎖リン酸化レベルには影響は与えず、アクチン・ミオシン相互作用を直接抑制することにより、その収縮を抑制するといわれている。blebbistatinはミオシンATPase加水分解サイクルに伴うミオシンのアクチンへの結合・解離に影響を及ぼすことが考えられることから、弛緩過程におけるクロスブリッジの解離にも影響を与えることが推察される。そこで本研究では、細胞膜を化学的に破壊して気管平滑筋スキンド標本のCa^<2+>収縮後の弛緩過程とミオシンATPaseサイクルの影響を受けないrigor形成・解離に対するblebbistatinの効果を動力学的に検討した。[方法] モルモット気管平滑筋に100μMのβ-escinで処理をしてスキンド標本を作製し、圧トランスデューサーに取り付けて等尺性張力を測定した。Ca^<2+>による最大収縮の後、EGTAによりCa^<2+>を素早く除去して弛緩させ、同時にblebbistatinを添加し15分間計測した。また、Ca^<2+>収縮後のrigor状態におけるblebbistatinについても同様の方法で検討した。統計処理はt-testを使用しP＜0.05を有意水準とした。[結果] Ca^<2+>収縮後の弛緩過程において、気管平滑筋スキンド標本は30μM程度で弛緩過程を促進し、回帰分析の結果からラッチの解離を速めていた。一方、Ca^<2+>収縮後のrigor状態では相対張力において有意な弛緩はみられなかったが、回帰分析の結果、30μMでrigorの解離の抑制と収縮後一度外れたクロスブリッジがrigorに移行する割合がコントロール群と比較して少ない値を示した。[考察] Blebbistatinは、ATPやアクチンのミオシンへの結合を直接阻害するのではなく、ミオシン頭部構造変化に影響してアクチン・ミオシン結合を弱めることが知られている。ATPの有無によって、Ca^<2+>収縮で発生した収縮張力のCa^<2+>除去後の減衰過程に対するblebbistatinの影響が異なるのは、blebbistatinがミオシン頭部構造変化に与える効果はミオシン頭部へのATPの結合の有無によって変化することを強く示唆する。平滑筋細胞において無酸素状態における力学反応の実態は不明であるが、blebbistatinはその解明に向けて研究において有用なツールになると考えられる。

Blebbistatin, an inhibitor of myosin II , has an inhibitory effect on smooth muscle actomyosin ATPase activity at around 10μM. Blebbistatin is also known to suppress the smooth contraction by direct inhibition of myosin-actin interaction without any effects on Ca^<2+> sensitivity to the force or phosphorylation level of myosin light chain. In the present study, to assess the blebbistatin effects on actin-myosin interaction in detail, we investigated effect of blebbistatin in the relaxation process and the reducing rigor tension after the Ca^<2+>-induced contraction using with skinned tracheal smooth muscle kinetically. A tracheal muscle preparation skinned (cell membrane permeabilized) with 100μM β-escin was attached to a force transducer to measure tension mechanical force. After contractile force induced with 10μM Ca^<2+> reached a steady level, Ca^<2+> was quickly removed in the absence or presence of ATP, resulting in relaxation process or reducing rigor tension respectively, with or without blebbistatin for 15 min. The relaxation process after the Ca^<2+>-removal was accelerated in the presence of 30μM blebbistatin and this effect of blebbistatin seemed to result from acceleration of detach from so called “latch” state. On the other hand, blebbistatin at 301M accelerated detachment of rigor bridge and reduced the forming rigor bridges in the absence of ATP, although the agent did not significantly changes in the tension level during decrease in the rigor tension after Ca^<2+> removal. The difference of the blebbistatin effects on the force between relaxation process and reducing rigor tension seems to be due to distinct effects of the agent on conformational changes of myosin in the absence and presence of ATP, because blebbistatin is known not to directly inhibit ATP binding to myosin, but to actin binding affinity of myosin.

首都大学東京, 2017-03-25, 修士（健康科学）

Subjects/Keywords: 気道平滑筋; ラッチ; ブレビスタチン; アクチン・ミオシン相互作用; airway smooth muscle; latch; blebbistatin; actin-myosin interaction

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

三橋, �. (2017). Blebbistatinによる気管平滑筋スキンド標本弛緩促進作用のメカニズム : Mechanisms of accelerating effect of blebbistatin on relaxation process of skinned tracheal smooth muscle. (Thesis). Tokyo Metropolitan University / 首都大学東京. Retrieved from http://hdl.handle.net/10748/00009633

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

三橋, 里子. “Blebbistatinによる気管平滑筋スキンド標本弛緩促進作用のメカニズム : Mechanisms of accelerating effect of blebbistatin on relaxation process of skinned tracheal smooth muscle.” 2017. Thesis, Tokyo Metropolitan University / 首都大学東京. Accessed January 25, 2021. http://hdl.handle.net/10748/00009633.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

三橋, 里子. “Blebbistatinによる気管平滑筋スキンド標本弛緩促進作用のメカニズム : Mechanisms of accelerating effect of blebbistatin on relaxation process of skinned tracheal smooth muscle.” 2017. Web. 25 Jan 2021.

Vancouver:

三橋 �. Blebbistatinによる気管平滑筋スキンド標本弛緩促進作用のメカニズム : Mechanisms of accelerating effect of blebbistatin on relaxation process of skinned tracheal smooth muscle. [Internet] [Thesis]. Tokyo Metropolitan University / 首都大学東京; 2017. [cited 2021 Jan 25]. Available from: http://hdl.handle.net/10748/00009633.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

三橋 �. Blebbistatinによる気管平滑筋スキンド標本弛緩促進作用のメカニズム : Mechanisms of accelerating effect of blebbistatin on relaxation process of skinned tracheal smooth muscle. [Thesis]. Tokyo Metropolitan University / 首都大学東京; 2017. Available from: http://hdl.handle.net/10748/00009633

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Aristotle University Of Thessaloniki (AUTH); Αριστοτέλειο Πανεπιστήμιο Θεσσαλονίκης (ΑΠΘ)

2. ΧΑΤΖΗΤΟΛΙΟΣ, ΑΠΟΣΤΟΛΟΣ. ΑΛΛΗΛΕΠΙΔΡΑΣΗ ΚΑΤΕΧΟΛΑΜΙΝΩΝ ΦΑΡΜΑΚΩΝ ΠΟΥ ΔΡΟΥΝ ΣΤΟΥΣ ΥΠΟΔΟΧΕΙΣ ΤΩΝ ΚΑΤΕΧΟΛΑΜΙΝΩΝ ΚΑΙ ΦΑΡΜΑΚΩΝ ΠΟΥ ΕΠΗΡΕΑΖΟΥΝ ΤΗΝ ΔΙΑΚΙΝΗΣΗ ΑΣΒΕΣΤΙΟΥ ΣΕ ΑΠΟΜΟΝΩΜΕΝΗ ΑΟΡΤΗ ΕΠΙΜΥΟΣ. ΔΙΕΡΕΥΝΗΣΗ ΤΗΣ ΔΡΑΣΕΩΣ ΤΗΣ ΑΜΙΩΔΑΡΟΝΗΣ.

Degree: 1986, Aristotle University Of Thessaloniki (AUTH); Αριστοτέλειο Πανεπιστήμιο Θεσσαλονίκης (ΑΠΘ)

URL: http://hdl.handle.net/10442/hedi/0807

►

THE PRESENT EXPERIMENTAL THESIS STUDIES THE INTERACTION OF CATECHOLAMINES, OF DRUGS WHICH ACT ON THE CATECHOLAMINES' RECEPTORS, AND OF DRUGS WHICH AFFECT THETRANSFER OF CALCIUM… (more)

▼

THE PRESENT EXPERIMENTAL THESIS STUDIES THE INTERACTION OF CATECHOLAMINES, OF DRUGS WHICH ACT ON THE CATECHOLAMINES' RECEPTORS, AND OF DRUGS WHICH AFFECT THETRANSFER OF CALCIUM ON THE ISOLATED RAT AORTA, HAVING THE RESEARCH ON THE AMIODARONE'S ACTION AS THE REFERENT POINT. MORE SPECIFICALLY , IT STUDIES THE EFFECT OF NORADRENALINE, POTASSIUM CHLORIDE, SEROTONIN, AND OF PROSTAGLANDIN F2A ON THE PREPARATION, WHILE SIMULTANEUSLY, IT EXAMINES THE VASODILATOR ACTION OF AMIODARONE AND ITS INTERACTION WITH THE USED VASOCONSTRICTIVE AGENTS, BOTH IN CALCIUM- CONTAINING AND IN CALCIUM-FREE SOLUTIONS, SO THAT THE ROLE OF EXTRACELLULAR CALCIUM IS IDENTIFIED DURING THE INTERACTIONS OF THE AGENTS USED. (SHORTENED)

ΣΤΗΝ ΠΑΡΟΥΣΑ ΕΡΕΥΝΗΤΙΚΗ ΕΡΓΑΣΙΑ ΜΕ ΣΗΜΕΙΟ ΑΝΑΦΟΡΑΣ ΤΗΝ ΔΙΕΡΕΥΝΗΣΗ ΤΗΣ ΔΡΑΣΕΩΣ ΤΗΣ ΑΜΙΩΔΑΡΟΝΗΣ ΜΕΛΕΤΗΘΗΚΕ ΣΕ ΑΠΟΜΟΝΩΜΕΝΗ ΑΟΡΤΗ ΕΠΙΜΥΟΣ Η ΑΛΛΗΛΕΠΙΔΡΑΣΗ ΚΑΤΕΧΟΛΑΜΙΝΩΝ, ΦΑΡΜΑΚΩΝ ΠΟΥ ΔΡΟΥΝ ΣΤΟΥΣ ΥΠΟΔΟΧΕΙΣ ΤΩΝ ΚΑΤΕΧΟΛΑΜΙΝΩΝ ΚΑΙ ΦΑΡΜΑΚΩΝ ΠΟΥ ΕΠΗΡΕΑΖΟΥΝ ΤΗΝ ΔΙΑΚΙΝΗΣΗ ΑΣΒΕΣΤΙΟΥ. ΕΙΔΙΚΟΤΕΡΑ ΜΕΛΕΤΗΘΗΚΕ Η ΕΠΙΔΡΑΣΗ ΣΤΟ ΠΑΡΑΣΚΕΥΑΣΜΑ ΤΗΣ ΝΟΡΑΔΡΕΝΑΛΙΝΗΣ, ΤΟΥ ΧΛΩΡΙΟΥΧΟΥ ΚΑΛΙΟΥ, ΤΗΣ ΣΕΡΟΤΟΝΙΝΗΣ ΚΑΙ ΤΗΣ ΠΡΟΣΤΑΓΛΑΝΔΙΝΗΣ F2A, ΕΝΩ ΣΥΓΧΡΟΝΩΣ ΔΙΕΡΕΥΝΗΘΗΚΕ Η ΑΓΓΕΙΟΔΙΑΣΤΑΛΤΙΚΗ ΔΡΑΣΗ ΤΗΣ ΑΜΙΩΔΑΡΟΝΗΣ ΚΑΙ Η ΑΛΛΗΛΕΠΙΔΡΑΣΗ ΤΗΣ ΜΕ ΑΓΓΕΙΟΣΥΣΠΑΣΤΙΚΕΣ ΟΥΣΙΕΣ ΠΟΥ ΧΡΗΣΙΜΟΠΟΙΗΘΗΚΑΝ, ΤΟΣΟ ΣΕ ΔΙΑΛΥΜΑ ΠΟΥ ΠΕΡΙΕΙΧΕ ΑΣΒΕΣΤΙΟ, ΟΣΟ ΚΑΙ ΣΕ ΔΙΑΛΥΜΑ ΣΤΕΡΗΜΕΝΟ ΑΣΒΕΣΤΙΟΥ, ΩΣΤΕ ΝΑ ΕΝΤΟΠΙΖΕΤΑΙ Ο ΡΟΛΟΣ ΤΟΥ ΕΞΩΓΕΝΟΥΣ ΑΣΒΕΣΤΙΟΥ ΚΑΤΑ ΤΗΝ ΑΛΛΗΛΕΠΙΔΡΑΣΗ ΤΩΝ ΟΥΣΙΩΝ. (ΠΕΡΙΚΟΠΗ)

Subjects/Keywords: ΑΓΓΕΙΑΚΗ ΛΕΙΑ ΜΥΙΚΗ ΙΝΑ; Αγγειοδιαστολή; ΑΛΛΗΛΕΠΙΔΡΑΣΗ ΦΑΡΜΑΚΩΝ; Αμιωδαρόνη; ΑΠΟΜΟΝΩΜΕΝΗ ΑΟΡΤΗ ΕΠΙΜΥΟΣ; Ιόντα ασβεστίου; Νοραδρεναλίνη; Προσταγλανδίνες; Σεροτονίνη; ΧΛΩΡΙΟΥΧΟ ΚΑΛΙΟ; Amiodarone; Calcium ions; DRUG INTERACTION; ISOLATED RAT AORTA; Noradrenaline; POTASSIUM CHLORIDE; Prostaglandins; Serotonine; VASCULAR SMOOTH MUSCLE; Vasodilatation

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

ΧΑΤΖΗΤΟΛΙΟΣ, . �. (1986). ΑΛΛΗΛΕΠΙΔΡΑΣΗ ΚΑΤΕΧΟΛΑΜΙΝΩΝ ΦΑΡΜΑΚΩΝ ΠΟΥ ΔΡΟΥΝ ΣΤΟΥΣ ΥΠΟΔΟΧΕΙΣ ΤΩΝ ΚΑΤΕΧΟΛΑΜΙΝΩΝ ΚΑΙ ΦΑΡΜΑΚΩΝ ΠΟΥ ΕΠΗΡΕΑΖΟΥΝ ΤΗΝ ΔΙΑΚΙΝΗΣΗ ΑΣΒΕΣΤΙΟΥ ΣΕ ΑΠΟΜΟΝΩΜΕΝΗ ΑΟΡΤΗ ΕΠΙΜΥΟΣ. ΔΙΕΡΕΥΝΗΣΗ ΤΗΣ ΔΡΑΣΕΩΣ ΤΗΣ ΑΜΙΩΔΑΡΟΝΗΣ. (Thesis). Aristotle University Of Thessaloniki (AUTH); Αριστοτέλειο Πανεπιστήμιο Θεσσαλονίκης (ΑΠΘ). Retrieved from http://hdl.handle.net/10442/hedi/0807

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

ΧΑΤΖΗΤΟΛΙΟΣ, ΑΠΟΣΤΟΛΟΣ. “ΑΛΛΗΛΕΠΙΔΡΑΣΗ ΚΑΤΕΧΟΛΑΜΙΝΩΝ ΦΑΡΜΑΚΩΝ ΠΟΥ ΔΡΟΥΝ ΣΤΟΥΣ ΥΠΟΔΟΧΕΙΣ ΤΩΝ ΚΑΤΕΧΟΛΑΜΙΝΩΝ ΚΑΙ ΦΑΡΜΑΚΩΝ ΠΟΥ ΕΠΗΡΕΑΖΟΥΝ ΤΗΝ ΔΙΑΚΙΝΗΣΗ ΑΣΒΕΣΤΙΟΥ ΣΕ ΑΠΟΜΟΝΩΜΕΝΗ ΑΟΡΤΗ ΕΠΙΜΥΟΣ. ΔΙΕΡΕΥΝΗΣΗ ΤΗΣ ΔΡΑΣΕΩΣ ΤΗΣ ΑΜΙΩΔΑΡΟΝΗΣ.” 1986. Thesis, Aristotle University Of Thessaloniki (AUTH); Αριστοτέλειο Πανεπιστήμιο Θεσσαλονίκης (ΑΠΘ). Accessed January 25, 2021. http://hdl.handle.net/10442/hedi/0807.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

ΧΑΤΖΗΤΟΛΙΟΣ, ΑΠΟΣΤΟΛΟΣ. “ΑΛΛΗΛΕΠΙΔΡΑΣΗ ΚΑΤΕΧΟΛΑΜΙΝΩΝ ΦΑΡΜΑΚΩΝ ΠΟΥ ΔΡΟΥΝ ΣΤΟΥΣ ΥΠΟΔΟΧΕΙΣ ΤΩΝ ΚΑΤΕΧΟΛΑΜΙΝΩΝ ΚΑΙ ΦΑΡΜΑΚΩΝ ΠΟΥ ΕΠΗΡΕΑΖΟΥΝ ΤΗΝ ΔΙΑΚΙΝΗΣΗ ΑΣΒΕΣΤΙΟΥ ΣΕ ΑΠΟΜΟΝΩΜΕΝΗ ΑΟΡΤΗ ΕΠΙΜΥΟΣ. ΔΙΕΡΕΥΝΗΣΗ ΤΗΣ ΔΡΑΣΕΩΣ ΤΗΣ ΑΜΙΩΔΑΡΟΝΗΣ.” 1986. Web. 25 Jan 2021.

Vancouver:

ΧΑΤΖΗΤΟΛΙΟΣ �. ΑΛΛΗΛΕΠΙΔΡΑΣΗ ΚΑΤΕΧΟΛΑΜΙΝΩΝ ΦΑΡΜΑΚΩΝ ΠΟΥ ΔΡΟΥΝ ΣΤΟΥΣ ΥΠΟΔΟΧΕΙΣ ΤΩΝ ΚΑΤΕΧΟΛΑΜΙΝΩΝ ΚΑΙ ΦΑΡΜΑΚΩΝ ΠΟΥ ΕΠΗΡΕΑΖΟΥΝ ΤΗΝ ΔΙΑΚΙΝΗΣΗ ΑΣΒΕΣΤΙΟΥ ΣΕ ΑΠΟΜΟΝΩΜΕΝΗ ΑΟΡΤΗ ΕΠΙΜΥΟΣ. ΔΙΕΡΕΥΝΗΣΗ ΤΗΣ ΔΡΑΣΕΩΣ ΤΗΣ ΑΜΙΩΔΑΡΟΝΗΣ. [Internet] [Thesis]. Aristotle University Of Thessaloniki (AUTH); Αριστοτέλειο Πανεπιστήμιο Θεσσαλονίκης (ΑΠΘ); 1986. [cited 2021 Jan 25]. Available from: http://hdl.handle.net/10442/hedi/0807.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

ΧΑΤΖΗΤΟΛΙΟΣ �. ΑΛΛΗΛΕΠΙΔΡΑΣΗ ΚΑΤΕΧΟΛΑΜΙΝΩΝ ΦΑΡΜΑΚΩΝ ΠΟΥ ΔΡΟΥΝ ΣΤΟΥΣ ΥΠΟΔΟΧΕΙΣ ΤΩΝ ΚΑΤΕΧΟΛΑΜΙΝΩΝ ΚΑΙ ΦΑΡΜΑΚΩΝ ΠΟΥ ΕΠΗΡΕΑΖΟΥΝ ΤΗΝ ΔΙΑΚΙΝΗΣΗ ΑΣΒΕΣΤΙΟΥ ΣΕ ΑΠΟΜΟΝΩΜΕΝΗ ΑΟΡΤΗ ΕΠΙΜΥΟΣ. ΔΙΕΡΕΥΝΗΣΗ ΤΗΣ ΔΡΑΣΕΩΣ ΤΗΣ ΑΜΙΩΔΑΡΟΝΗΣ. [Thesis]. Aristotle University Of Thessaloniki (AUTH); Αριστοτέλειο Πανεπιστήμιο Θεσσαλονίκης (ΑΠΘ); 1986. Available from: http://hdl.handle.net/10442/hedi/0807

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Kyoto University / 京都大学

3. Adnan Hamid. Direct Numerical Simulation Studies of Sedimentation of Spherical Particles : 直接数値シミュレーションによる球状粒子の沈降に関する研究.

Degree: 博士(工学), 2014, Kyoto University / 京都大学

URL: http://hdl.handle.net/2433/188621 ; http://dx.doi.org/10.14989/doctor.k18306

新制・課程博士

甲第18306号

工博第3898号

Subjects/Keywords: Colloid; Sedimentation; Direct Numerical Simulation; Hydrodynamic Interaction; Diffusion; Smooth Profile Method

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Hamid, A. (2014). Direct Numerical Simulation Studies of Sedimentation of Spherical Particles : 直接数値シミュレーションによる球状粒子の沈降に関する研究. (Thesis). Kyoto University / 京都大学. Retrieved from http://hdl.handle.net/2433/188621 ; http://dx.doi.org/10.14989/doctor.k18306

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Hamid, Adnan. “Direct Numerical Simulation Studies of Sedimentation of Spherical Particles : 直接数値シミュレーションによる球状粒子の沈降に関する研究.” 2014. Thesis, Kyoto University / 京都大学. Accessed January 25, 2021. http://hdl.handle.net/2433/188621 ; http://dx.doi.org/10.14989/doctor.k18306.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Hamid, Adnan. “Direct Numerical Simulation Studies of Sedimentation of Spherical Particles : 直接数値シミュレーションによる球状粒子の沈降に関する研究.” 2014. Web. 25 Jan 2021.

Vancouver:

Hamid A. Direct Numerical Simulation Studies of Sedimentation of Spherical Particles : 直接数値シミュレーションによる球状粒子の沈降に関する研究. [Internet] [Thesis]. Kyoto University / 京都大学; 2014. [cited 2021 Jan 25]. Available from: http://hdl.handle.net/2433/188621 ; http://dx.doi.org/10.14989/doctor.k18306.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Hamid A. Direct Numerical Simulation Studies of Sedimentation of Spherical Particles : 直接数値シミュレーションによる球状粒子の沈降に関する研究. [Thesis]. Kyoto University / 京都大学; 2014. Available from: http://hdl.handle.net/2433/188621 ; http://dx.doi.org/10.14989/doctor.k18306

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

4. Adnan Hamid. Direct Numerical Simulation Studies of Sedimentation of Spherical Particles .

Degree: 2014, Kyoto University

URL: http://hdl.handle.net/2433/188621

Subjects/Keywords: Colloid; Sedimentation; Direct Numerical Simulation; Hydrodynamic Interaction; Diffusion; Smooth Profile Method

…distribution function Re Reynolds number SP Smooth profile SRD Stochastic rotational dynamics… …thickness in RDF l Size of hypothetical blob of fluid ϕ(x) Smooth profile function… …middle plane, the interaction of the velocity field of a particle with other particles is… …larger than the velocity field of the particle near the walls. This strong interaction of… …induce the deficiency of particles. At high volume fractions, this weak interaction competes…

10 more images…

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Hamid, A. (2014). Direct Numerical Simulation Studies of Sedimentation of Spherical Particles . (Thesis). Kyoto University. Retrieved from http://hdl.handle.net/2433/188621

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Hamid, Adnan. “Direct Numerical Simulation Studies of Sedimentation of Spherical Particles .” 2014. Thesis, Kyoto University. Accessed January 25, 2021. http://hdl.handle.net/2433/188621.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Hamid, Adnan. “Direct Numerical Simulation Studies of Sedimentation of Spherical Particles .” 2014. Web. 25 Jan 2021.

Vancouver:

Hamid A. Direct Numerical Simulation Studies of Sedimentation of Spherical Particles . [Internet] [Thesis]. Kyoto University; 2014. [cited 2021 Jan 25]. Available from: http://hdl.handle.net/2433/188621.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Hamid A. Direct Numerical Simulation Studies of Sedimentation of Spherical Particles . [Thesis]. Kyoto University; 2014. Available from: http://hdl.handle.net/2433/188621

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Minnesota

5. Depouhon, Alexandre F.B.E. Integrated dynamical models of down-the-hole percussive drilling.

Degree: PhD, Civil Engineering, 2014, University of Minnesota

URL: http://hdl.handle.net/11299/170117

► Due to the overall process complexity, studies about percussive drilling usually focus on a limited set of the (sub)processes underlying it, e.g., the hammer thermodynamics… (more)

▼ Due to the overall process complexity, studies about percussive drilling usually focus on a limited set of the (sub)processes underlying it, e.g., the hammer thermodynamics or the interaction between the bit and the rock. Following this paradigm, the assessment of the process performance is typically performed by considering a single percussive activation and a single interaction cycle between the bit and the rock, from arbitrary initial conditions.The need for an integrated approach to evaluate drilling performance, based on the dynamical interaction of the (sub)processes underlying drilling, is evident. Such an approach requires simplified models, however, as the computational cost associated with full scale models is simply unbearable. In this thesis, three dynamical integrated models are proposed and a preliminary analysis is conducted for a reference configuration and around it. The models couple three modules that represent: (i) the dynamics of the mechanical system, (ii) the interaction between the bit and the rock, and (iii) the activation of the mechanical system. For each module, simple representations are considered; of particular importance is the bit/rock interaction model which is a generalization to repeated interactions of experimental evidence observed for a single interaction.In the first model, the dynamics of a rigid bit is cast into a drifting oscillator and the activation modeled as a periodic impulsive force. The second and third models account for the dynamics of the piston and the activation results from the impact of the piston on the bit. They are respectively based on elastic and rigid representations of the two bodies. In the rigid model, analytical results of wave propagation in thin rods are used to represent the contact interaction between the piston and the bit. In the elastic model, wave propagation is resolved.Their preliminary analysis has revealed the occurrence of complex dynamical responses in the space of parameters. Expected trends are recovered around a reference configuration corresponding to a low-size hammer, with an increase of the rate of penetration with the feed force and the percussive frequency. An important sensitivity of the rate of penetration to the latter parameter is uncovered. Interestingly, our analyses show that when the activation period has the same order of magnitude as the timescale associated with the bit/rock interaction, a lower power consumption is observed, indicating a possible resonance phenomenon in the drilling system. Also, the predictions of the rigid model are shown to be in good agreement with the ones of the elastic model, in the explored range of parameters.Given the piecewise linear nature of the proposed models, dedicated numerical tools have been developed to conduct their analysis. As such, the thesis proposes a high-order time integration scheme for linear structural dynamics as well as a novel framework to evaluate the accuracy of such schemes, and a root-solving module to perform event-detection, for coupling with event-driven…

Subjects/Keywords: Bit/rock interaction; Dynamical systems; Percussive drilling; Piecewise smooth; Structural dynamics; Civil engineering

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Depouhon, A. F. B. E. (2014). Integrated dynamical models of down-the-hole percussive drilling. (Doctoral Dissertation). University of Minnesota. Retrieved from http://hdl.handle.net/11299/170117

Chicago Manual of Style (16^th Edition):

Depouhon, Alexandre F B E. “Integrated dynamical models of down-the-hole percussive drilling.” 2014. Doctoral Dissertation, University of Minnesota. Accessed January 25, 2021. http://hdl.handle.net/11299/170117.

MLA Handbook (7^th Edition):

Depouhon, Alexandre F B E. “Integrated dynamical models of down-the-hole percussive drilling.” 2014. Web. 25 Jan 2021.

Vancouver:

Depouhon AFBE. Integrated dynamical models of down-the-hole percussive drilling. [Internet] [Doctoral dissertation]. University of Minnesota; 2014. [cited 2021 Jan 25]. Available from: http://hdl.handle.net/11299/170117.

Council of Science Editors:

Depouhon AFBE. Integrated dynamical models of down-the-hole percussive drilling. [Doctoral Dissertation]. University of Minnesota; 2014. Available from: http://hdl.handle.net/11299/170117

6. Desormeaux, Kevin. Temporal models of motions and forces for Human-Robot Interactive manipulation : Modèles temporels du mouvement et des forces pour la manipulation Interactive Homme-Robot.

Degree: Docteur es, Robotique, Informatique, 2019, Université Toulouse III – Paul Sabatier

URL: http://www.theses.fr/2019TOU30221

►

L'intérêt pour la robotique a débuté dans les années 70 et depuis les robots n'ont cessé de remplacer les humains dans l'industrie. L'automatisation à outrance… (more)

▼

L'intérêt pour la robotique a débuté dans les années 70 et depuis les robots n'ont cessé de remplacer les humains dans l'industrie. L'automatisation à outrance n'apporte cependant pas que des avantages, car elle nécessite des environnements parfaitement contrôlés et la reprogrammation d'une tâche est longue et fastidieuse. Le besoin accru d'adaptabilité et de ré-utilisabilité des systèmes d'assemblage force la robotique à se révolutionner en amenant notamment l'homme et le robot à interagir. Ce nouveau type de collaboration permet de combiner les forces respectives des humains et des robots. Cependant l'homme ne pourra être inclus en tant qu'agent actif dans ces nouveaux espaces de travail collaboratifs que si l'on dispose de robots sûrs, intuitifs et facilement reprogrammables. C'est à la lumière de ce constat qu'on peut deviner le rôle crucial de la génération de mouvement pour les robots de demain. Pour que les humains et les robots puissent collaborer, ces derniers doivent générer des mouvements sûrs afin de garantir la sécurité de l'homme tant physique que psychologique. Les trajectoires sont un excellent modèle pour la génération de mouvements adaptés aux robots collaboratifs, car elles offrent une description simple et précise de l'évolution du mouvement. Les trajectoires dîtes souples sont bien connues pour générer des mouvements sûrs et confortables pour l'homme. Dans cette thèse nous proposons un algorithme de génération de trajectoires temps-réel basé sur des séquences de segments de fonctions polynomiales de degré trois pour construire des trajectoires souples. Ces trajectoires sont construites à partir de conditions initiales et finales arbitraires, une condition nécessaire pour que les robots soient capables de réagir instantanément à des événements imprévus. L'approche basée sur un modèle à jerk-contraint offre des solutions orientées performance: les trajectoires sont optimales en temps sous contraintes de sécurité. Ces contraintes de sécurité sont des contraintes cinématiques qui dépendent de la tâche et du contexte et doivent être spécifiées. Pour guider le choix de ces contraintes, nous avons étudié le rôle de la cinématique dans la définition des propriétés ergonomiques du mouvement.[...]

It was in the 70s when the interest for robotics really emerged. It was barely half a century ago, and since then robots have been replacing humans in the industry. This robot-oriented solution doesn't come without drawbacks as full automation requires time-consuming programming as well as rigid environments. With the increased need for adaptability and reusability of assembly systems, robotics is undergoing major changes and see the emergence of a new type of collaboration between humans and robots. Human-Robot collaboration get the best of both world by combining the respective strengths of humans and robots. But, to include the human as an active agent in these new collaborative workspaces, safe and flexible robots are required. It is in this context that we can apprehend the crucial role of motion…

Advisors/Committee Members: Sidobre, Daniel (thesis director).

Subjects/Keywords: Génération de trajectoires en temps-réel; Interaction homme-robot; Contrôle réactif de trajectoires; Trajectoires souples; Ergonomie du mouvement; Online Trajectory Generation; Human-Robot Interaction; Reactive Trajectory Control; Smooth Trajectories; Motion Ergonomics

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Desormeaux, K. (2019). Temporal models of motions and forces for Human-Robot Interactive manipulation : Modèles temporels du mouvement et des forces pour la manipulation Interactive Homme-Robot. (Doctoral Dissertation). Université Toulouse III – Paul Sabatier. Retrieved from http://www.theses.fr/2019TOU30221

Chicago Manual of Style (16^th Edition):

Desormeaux, Kevin. “Temporal models of motions and forces for Human-Robot Interactive manipulation : Modèles temporels du mouvement et des forces pour la manipulation Interactive Homme-Robot.” 2019. Doctoral Dissertation, Université Toulouse III – Paul Sabatier. Accessed January 25, 2021. http://www.theses.fr/2019TOU30221.

MLA Handbook (7^th Edition):

Desormeaux, Kevin. “Temporal models of motions and forces for Human-Robot Interactive manipulation : Modèles temporels du mouvement et des forces pour la manipulation Interactive Homme-Robot.” 2019. Web. 25 Jan 2021.

Vancouver:

Desormeaux K. Temporal models of motions and forces for Human-Robot Interactive manipulation : Modèles temporels du mouvement et des forces pour la manipulation Interactive Homme-Robot. [Internet] [Doctoral dissertation]. Université Toulouse III – Paul Sabatier; 2019. [cited 2021 Jan 25]. Available from: http://www.theses.fr/2019TOU30221.

Council of Science Editors:

Desormeaux K. Temporal models of motions and forces for Human-Robot Interactive manipulation : Modèles temporels du mouvement et des forces pour la manipulation Interactive Homme-Robot. [Doctoral Dissertation]. Université Toulouse III – Paul Sabatier; 2019. Available from: http://www.theses.fr/2019TOU30221

Vanderbilt University

7. Erol, Duygun. Design of an Intelligent Control Architecture for Rehabilitation Robotics.

Degree: PhD, Electrical Engineering, 2007, Vanderbilt University

URL: http://hdl.handle.net/1803/12613

► Robot-assisted rehabilitation has been an active research area for the last few years to automate therapy for regaining mobility with arm and hand movements following… (more)

▼ Robot-assisted rehabilitation has been an active research area for the last few years to automate therapy for regaining mobility with arm and hand movements following a deficiency in facility due to stroke. However, task-oriented therapy approaches that require patients to practice complex and more-functional activities of daily living (ADL) tasks cannot be performed by the existing robot-assisted rehabilitation systems because they are only limited to providing assistance to either arm or hand movement. Therefore, an intelligent controller for robot-assisted rehabilitation systems is desirable in order to perform ADL tasks that generally require coordination of both arm and hand movements. In this dissertation, an intelligent control architecture is designed to coordinate in-house designed assistive devices in a systematic manner to enable the stroke patients to perform ADL tasks. The proposed control architecture is the first of its kind that brings the benefit of coordination of arm and hand assistive devices which is expected to address the deficit of coordinated assistive devices in the field of rehabilitation robotics. The control architecture is represented in terms of a hybrid system model combining a high-level controller for decision-making and two low-level assistive controllers (arm and hand controllers) for providing arm and hand motion assistance. The application of a hybrid system model for rehabilitation purposes is unique. Furthermore, providing robotic assistance to the patients to complete the rehabilitation task in a smooth manner is an important objective in rehabilitation therapies. Thus, the low-level assistive controllers in the control architecture are designed in such a way as to enhance smooth human-robot interaction involving the subject and the robotic assistive devices. Results from real-time assistance experiments on unimpaired subjects are presented to demonstrate the efficacy of the presented control architecture. Advisors/Committee Members: Dr. Mitch Wilkes (committee member), Dr. George E. Cook (committee member), Dr. Michael Goldfarb (committee member), Dr. Thomas E. Groomes (committee member), Dr. Nilanjan Sarkar (Committee Chair).

Subjects/Keywords: Robots – Control systems; Cerebrovascular disease Patients Rehabilitation; robot-assisted rehabilitation for ADL tasks; gain scheduling; smooth interaction; human arm parameter estimation; robot-assisted rehabilitation; coordination of arm and hand assistive devices; hybrid system model; Computerized self-help devices for people with disabilities

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Erol, D. (2007). Design of an Intelligent Control Architecture for Rehabilitation Robotics. (Doctoral Dissertation). Vanderbilt University. Retrieved from http://hdl.handle.net/1803/12613

Chicago Manual of Style (16^th Edition):

Erol, Duygun. “Design of an Intelligent Control Architecture for Rehabilitation Robotics.” 2007. Doctoral Dissertation, Vanderbilt University. Accessed January 25, 2021. http://hdl.handle.net/1803/12613.

MLA Handbook (7^th Edition):

Erol, Duygun. “Design of an Intelligent Control Architecture for Rehabilitation Robotics.” 2007. Web. 25 Jan 2021.

Vancouver:

Erol D. Design of an Intelligent Control Architecture for Rehabilitation Robotics. [Internet] [Doctoral dissertation]. Vanderbilt University; 2007. [cited 2021 Jan 25]. Available from: http://hdl.handle.net/1803/12613.

Council of Science Editors:

Erol D. Design of an Intelligent Control Architecture for Rehabilitation Robotics. [Doctoral Dissertation]. Vanderbilt University; 2007. Available from: http://hdl.handle.net/1803/12613

Penn State University

8. Lescoe, Ryan. Improvement of Soil Modeling in a Tire-Soil Interaction Using Finite Element Analysis and Smooth Particle Hydrodynamics .

Degree: 2010, Penn State University

URL: https://submit-etda.libraries.psu.edu/catalog/10823

► In recent years, the advancement of computerized modeling has allowed for the creation of extensive pneumatic tire models. These models have been used to determine… (more)

▼ In recent years, the advancement of computerized modeling has allowed for the creation of extensive pneumatic tire models. These models have been used to determine many tire properties and tire-road interaction parameters which are either prohibitively expensive or unavailable with physical models. More recently, computerized modeling has been used to explore tire-soil interactions. The new parameters created by these interactions were defined for these models, but accurate soil constitutive equations were lacking. With the previous models, the soil was simulated using Finite Element Analysis (FEA) with soil material models requiring calibration and validation. Furthermore, the meshless modeling method of Smooth Particle Hydrodynamics (SPH) may be a viable approach to more accurately simulating large soil deformations and complex tire-soil interactions. For this thesis, a rigid tire model is used to perform an extensive sensitivity study on the previously used FEA soft soil (dense sand) in order to determine the importance of mesh size, soil plot size, and edge constraints. Then, parameters for SPH particles are determined for either complete or partial replacement of FEA elements in the soil model. Rolling resistance tests are conducted with a rigid tire model for different SPH and FEA/SPH soil models and compared to the previously determined best FEA soil model. Replacement of FEA elements with SPH particles is found to be the key variable as using a deeper amount of SPH particles increases rolling resistance while increasing the SPH particle density has little effect on rolling resistance. These results are then replicated using a pneumatic tire model. For further validation, pressure-sinkage tests are conducted with the FEA and SPH soils to explore the differences in the two soil modeling methods. Also, shear-displacement tests are conducted with the SPH soil—a test which cannot easily be performed with an FEA soil model. These shear tests show that the SPH soil behaves more like a clay in initial shearing and more like a sand by exhibiting increased shearing due to vertical loading. Furthermore, both the pressure-sinkage and shear-displacement tests still indicate that a larger particle density is unnecessary. Advisors/Committee Members: Moustafa El Gindy, Thesis Advisor/Co-Advisor, Moustafa El Gindy, Thesis Advisor/Co-Advisor, Kevin L Koudela, Thesis Advisor/Co-Advisor.

Subjects/Keywords: smoothed; smooth particle hydrodynamics; FEA; finite element analysis; tire-soil interaction; soil modeling; SPH; PAM-Crash; PAM-Shock; pneumatic tire; rigid tire

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Lescoe, R. (2010). Improvement of Soil Modeling in a Tire-Soil Interaction Using Finite Element Analysis and Smooth Particle Hydrodynamics . (Thesis). Penn State University. Retrieved from https://submit-etda.libraries.psu.edu/catalog/10823

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Lescoe, Ryan. “Improvement of Soil Modeling in a Tire-Soil Interaction Using Finite Element Analysis and Smooth Particle Hydrodynamics .” 2010. Thesis, Penn State University. Accessed January 25, 2021. https://submit-etda.libraries.psu.edu/catalog/10823.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Lescoe, Ryan. “Improvement of Soil Modeling in a Tire-Soil Interaction Using Finite Element Analysis and Smooth Particle Hydrodynamics .” 2010. Web. 25 Jan 2021.

Vancouver:

Lescoe R. Improvement of Soil Modeling in a Tire-Soil Interaction Using Finite Element Analysis and Smooth Particle Hydrodynamics . [Internet] [Thesis]. Penn State University; 2010. [cited 2021 Jan 25]. Available from: https://submit-etda.libraries.psu.edu/catalog/10823.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Lescoe R. Improvement of Soil Modeling in a Tire-Soil Interaction Using Finite Element Analysis and Smooth Particle Hydrodynamics . [Thesis]. Penn State University; 2010. Available from: https://submit-etda.libraries.psu.edu/catalog/10823

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Queens University

9. Liu, Shifang. Statistical Methods for Testing Treatment-Covariate Interactions in Cancer Clinical Trials .

Degree: Mathematics and Statistics, 2011, Queens University

URL: http://hdl.handle.net/1974/6758

► Treatment–covariate interaction is often used in clinical trials to assess the homogeneity of treatment effects over these subgroups defined by a baseline covariate, which is… (more)

Subjects/Keywords: Jackknife estimate ; Monte-Carlo simulation ; nonparametric measure of interaction ; Kernel smooth

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Liu, S. (2011). Statistical Methods for Testing Treatment-Covariate Interactions in Cancer Clinical Trials . (Thesis). Queens University. Retrieved from http://hdl.handle.net/1974/6758

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Liu, Shifang. “Statistical Methods for Testing Treatment-Covariate Interactions in Cancer Clinical Trials .” 2011. Thesis, Queens University. Accessed January 25, 2021. http://hdl.handle.net/1974/6758.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Liu, Shifang. “Statistical Methods for Testing Treatment-Covariate Interactions in Cancer Clinical Trials .” 2011. Web. 25 Jan 2021.

Vancouver:

Liu S. Statistical Methods for Testing Treatment-Covariate Interactions in Cancer Clinical Trials . [Internet] [Thesis]. Queens University; 2011. [cited 2021 Jan 25]. Available from: http://hdl.handle.net/1974/6758.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Liu S. Statistical Methods for Testing Treatment-Covariate Interactions in Cancer Clinical Trials . [Thesis]. Queens University; 2011. Available from: http://hdl.handle.net/1974/6758

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Brno University of Technology

10. Obr, Jakub. Pokročilá simulace a vizualizace kapaliny: Advanced Simulation and Vizualization of a Fluid.

Degree: 2019, Brno University of Technology

URL: http://hdl.handle.net/11012/54227

► This thesis concentrates on physically based simulation of fluids followed by its photorealistic visualization. It describes one form of Smooth Particle Hydrodynamics methods for viscoelastic… (more)

Subjects/Keywords: simulace kapaliny; vizualizace kapaliny; Smooth Particles Hydrodynamics; SPH; neviditelné hraniční částice; interakce více kapalin; Ray Tracing; totální odrazy; vizualizace transparentního objektu; Marching Cubes; problém interpolace normál; liquid simulation; liquid visualization; Smooth Particles Hydrodynamics; SPH; fixed boundary particles; multiple fluids interaction; Ray Tracing; total reflections; transparent object visualization; Marching Cubes; normal interpolation problem

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Obr, J. (2019). Pokročilá simulace a vizualizace kapaliny: Advanced Simulation and Vizualization of a Fluid. (Thesis). Brno University of Technology. Retrieved from http://hdl.handle.net/11012/54227

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Obr, Jakub. “Pokročilá simulace a vizualizace kapaliny: Advanced Simulation and Vizualization of a Fluid.” 2019. Thesis, Brno University of Technology. Accessed January 25, 2021. http://hdl.handle.net/11012/54227.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Obr, Jakub. “Pokročilá simulace a vizualizace kapaliny: Advanced Simulation and Vizualization of a Fluid.” 2019. Web. 25 Jan 2021.

Vancouver:

Obr J. Pokročilá simulace a vizualizace kapaliny: Advanced Simulation and Vizualization of a Fluid. [Internet] [Thesis]. Brno University of Technology; 2019. [cited 2021 Jan 25]. Available from: http://hdl.handle.net/11012/54227.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Obr J. Pokročilá simulace a vizualizace kapaliny: Advanced Simulation and Vizualization of a Fluid. [Thesis]. Brno University of Technology; 2019. Available from: http://hdl.handle.net/11012/54227

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

11. Rothwell, Clayton D. Multi-Sensory Integration in Motion Perception: Do Moving Sounds Facilitate/Interfere with Smooth Pursuit Eye Movements?.

Degree: MS, Human Factors and Industrial/Organizational Psychology MS, 2014, Wright State University

URL: http://rave.ohiolink.edu/etdc/view?acc_num=wright1413319214

► Previous experiments have attempted to measure smooth pursuit eye movements (SPEM) to acoustic targets with limited success. Some studies found no evidence for SPEM (Gauthier… (more)

Subjects/Keywords: Psychology; Experimental Psychology; Cognitive Psychology; perception; psychophysics; vision; hearing; psychoacoustics; motion; eye tracking; smooth pursuit eye movements; multi-sensory; multi-modal; integration; interaction; ventriloquism effect; perceptual alignment

…dear friends and wonderful mentors. ix Introduction Smooth pursuit eye movements (… …positions in response to a moving target illustrating (a) smooth pursuit and (b… …elicit SPEM combined with the findings of multimodal interaction raise the possibility of… …as would be the case in smooth pursuit compared to saccades and fixations. The decreasing… …to be in response to perceived motion, multimodal interaction (if it occurs) may…

2 more images…

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Rothwell, C. D. (2014). Multi-Sensory Integration in Motion Perception: Do Moving Sounds Facilitate/Interfere with Smooth Pursuit Eye Movements?. (Masters Thesis). Wright State University. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=wright1413319214

Chicago Manual of Style (16^th Edition):

Rothwell, Clayton D. “Multi-Sensory Integration in Motion Perception: Do Moving Sounds Facilitate/Interfere with Smooth Pursuit Eye Movements?.” 2014. Masters Thesis, Wright State University. Accessed January 25, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=wright1413319214.

MLA Handbook (7^th Edition):

Rothwell, Clayton D. “Multi-Sensory Integration in Motion Perception: Do Moving Sounds Facilitate/Interfere with Smooth Pursuit Eye Movements?.” 2014. Web. 25 Jan 2021.

Vancouver:

Rothwell CD. Multi-Sensory Integration in Motion Perception: Do Moving Sounds Facilitate/Interfere with Smooth Pursuit Eye Movements?. [Internet] [Masters thesis]. Wright State University; 2014. [cited 2021 Jan 25]. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=wright1413319214.

Council of Science Editors:

Rothwell CD. Multi-Sensory Integration in Motion Perception: Do Moving Sounds Facilitate/Interfere with Smooth Pursuit Eye Movements?. [Masters Thesis]. Wright State University; 2014. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=wright1413319214

Delft University of Technology

12. Vasulkar, Amey (author). Modeling of periodic non-smooth motion using the harmonic balance method.

Degree: 2018, Delft University of Technology

URL: http://resolver.tudelft.nl/uuid:68afebe1-b2a9-4a8e-8e44-2d56bc8bb085

►

The company Deepwater Energy BV, Netherlands developed a unique water turbine called as the Oryon Watermill (OWM). It was the aim of the company to… (more)

Subjects/Keywords: harmonic balance method; non-smooth dynamics; Fluid Structure Interaction; OpenFOAM; unilateral contacts

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Vasulkar, A. (. (2018). Modeling of periodic non-smooth motion using the harmonic balance method. (Masters Thesis). Delft University of Technology. Retrieved from http://resolver.tudelft.nl/uuid:68afebe1-b2a9-4a8e-8e44-2d56bc8bb085

Chicago Manual of Style (16^th Edition):

Vasulkar, Amey (author). “Modeling of periodic non-smooth motion using the harmonic balance method.” 2018. Masters Thesis, Delft University of Technology. Accessed January 25, 2021. http://resolver.tudelft.nl/uuid:68afebe1-b2a9-4a8e-8e44-2d56bc8bb085.

MLA Handbook (7^th Edition):

Vasulkar, Amey (author). “Modeling of periodic non-smooth motion using the harmonic balance method.” 2018. Web. 25 Jan 2021.

Vancouver:

Vasulkar A(. Modeling of periodic non-smooth motion using the harmonic balance method. [Internet] [Masters thesis]. Delft University of Technology; 2018. [cited 2021 Jan 25]. Available from: http://resolver.tudelft.nl/uuid:68afebe1-b2a9-4a8e-8e44-2d56bc8bb085.

Council of Science Editors:

Vasulkar A(. Modeling of periodic non-smooth motion using the harmonic balance method. [Masters Thesis]. Delft University of Technology; 2018. Available from: http://resolver.tudelft.nl/uuid:68afebe1-b2a9-4a8e-8e44-2d56bc8bb085

University of Toronto

13. Xu, Songyi. N-cadherin Regulation of Vascular Smooth Muscle Cells; the Role of DDR1 and Rho GTPases.

Degree: PhD, 2020, University of Toronto

URL: http://hdl.handle.net/1807/101328

► N-cadherin mediates cell-cell contacts in vascular smooth muscle cells (VSMCs) and regulates VSMC behaviours. Discoidin domain receptor 1 (DDR1) is a collagen binding receptor also… (more)

▼ N-cadherin mediates cell-cell contacts in vascular smooth muscle cells (VSMCs) and regulates VSMC behaviours. Discoidin domain receptor 1 (DDR1) is a collagen binding receptor also implicated in these processes. Previous studies showed that both N-cadherin and DDR1 are upregulated after vascular injury, but it is not known whether the two molecules are associated. The ability to establish proper N-cadherin junctions is important in regulating VSMC behaviour. In my studies, I found that N-cadherin could associate with DDR1, and that this association was increased during VSMC migration and wound closure. I found that N-cadherin was reduced in lipid rafts and mislocalized from cell-cell junctions in the absence of DDR1. Disruption of lipid rafts by cholesterol oxidase or methyl-β-cyclodextrin removed N-cadherin from lipid rafts of DDR1+/+ VSMCs and disrupted N-cadherin contacts, and these effects were reversed by cholesterol rescue that restored lipid rafts. Knockdown of DDR1 by siRNA resulted in mislocalized N-cadherin contacts from cell junctions, and transfection of DDR1-/- VSMCs with full-length DDR1 rescued the formation of N-cadherin junctions. The mislocalization of N-cadherin contacts in DDR1-/- VSMCs was also accompanied by disruption of the actin cytoskeleton. N-cadherin contacts in VSMCs undergo constant remodeling, especially during disease processes. Calcium switch to disrupt and restore contacts did not affect N-cadherin triton solubility in DDR1+/+ and DDR1-/- VSMCs or the association between N-cadherin and DDR1. While collagen stimulation of DDR1 increased the association between N-cadherin and DDR1 in cells with mature, well-established cell contacts, it did not affect N-cadherin localization, its triton solubility, or the association between N-cadherin and DDR1 during contact disruption, restoration, and wound closure. Rho GTPases are master regulators of the cytoskeleton and can mediate cytoskeletal processes downstream of cell-cell contacts. Using calcium switch and plating on either IgG or N-cadherin-Fc coated surfaces, active Rho GTPase pull-down assays showed a consistent decrease in Cdc42 and RhoA activity after N-cadherin contact establishment in DDR1+/+ SMCs. Overall, these data reveal that N-cadherin cell-cell contacts in VSMCs can be regulated through interaction with DDR1 and localization in lipid rafts, and that the establishment of N-cadherin contacts can suppress Rho GTPase activity. Advisors/Committee Members: Bendeck, Michelle, Laboratory Medicine and Pathobiology.

Subjects/Keywords: Cell-cell interaction; DDR1; N-cadherin; Rho GTPases; Vascular smooth muscle cells; 0307

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Xu, S. (2020). N-cadherin Regulation of Vascular Smooth Muscle Cells; the Role of DDR1 and Rho GTPases. (Doctoral Dissertation). University of Toronto. Retrieved from http://hdl.handle.net/1807/101328

Chicago Manual of Style (16^th Edition):

Xu, Songyi. “N-cadherin Regulation of Vascular Smooth Muscle Cells; the Role of DDR1 and Rho GTPases.” 2020. Doctoral Dissertation, University of Toronto. Accessed January 25, 2021. http://hdl.handle.net/1807/101328.

MLA Handbook (7^th Edition):

Xu, Songyi. “N-cadherin Regulation of Vascular Smooth Muscle Cells; the Role of DDR1 and Rho GTPases.” 2020. Web. 25 Jan 2021.

Vancouver:

Xu S. N-cadherin Regulation of Vascular Smooth Muscle Cells; the Role of DDR1 and Rho GTPases. [Internet] [Doctoral dissertation]. University of Toronto; 2020. [cited 2021 Jan 25]. Available from: http://hdl.handle.net/1807/101328.

Council of Science Editors:

Xu S. N-cadherin Regulation of Vascular Smooth Muscle Cells; the Role of DDR1 and Rho GTPases. [Doctoral Dissertation]. University of Toronto; 2020. Available from: http://hdl.handle.net/1807/101328

		in
And / Or
		in
And / Or
		in
And / Or
		in

Open Access Theses and Dissertations