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Delft University of Technology

1. Kamath, U.R. (author). Design of high-resolution photodiode readout circuitry for a bio-implantable continuous glucose sensing chip.

Degree: 2012, Delft University of Technology

Glucose sensors are useful for monitoring and control of blood-sugar concentration for diabetic patients. There are many challenges in their wide-spread use and effectiveness in control of the disease. This work is a step towards achieving in vivo continuous long-term glucose monitoring using the optical near-infrared based glucose sensing principle. The thesis investigates and arrives at an architecture for the readout circuitry of such a sensor system. The goal is that the realized CMOS chip together with the optical sensing devices realized in Silicon-on-Insulator technology will form a single-implantable solution. The advantage is the long-term monitoring due to non-usage of chemical reagents. The thesis work addresses the read-out circuit requirements for a photodiode as part of such a sensor. The design of a high-resolution current-input sigma-delta ADC is discussed which targets to achieve 16-bit resolution for a photo-diode signal in the range of 100nA-10?A. Various optimizations for specifications such as noise, accuracy and energy-efficiency both at circuit and system level are addressed. The chip has been realized in a TSMC 0.18?m process. The initial measurements show the functionality of the ADC and its performance using the test set-up developed. A proof of concept of the optical-electrical interface with a photodiode shows the application of the circuit.

Microelectronics

Electronic Instrumentation Laboratory

Electrical Engineering, Mathematics and Computer Science

Advisors/Committee Members: Pertijs, M.A.P. (mentor), San Segundo Bello, D. (mentor).

Subjects/Keywords: glucose sensor; incremental Sigma-Delta; current input ADC; dynamic reference; wide-dynamic range; sensor adaptable ADC

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Kamath, U. R. (. (2012). Design of high-resolution photodiode readout circuitry for a bio-implantable continuous glucose sensing chip. (Masters Thesis). Delft University of Technology. Retrieved from http://resolver.tudelft.nl/uuid:ea9d2e1c-5b03-44e9-b916-587fd737313f

Chicago Manual of Style (16th Edition):

Kamath, U R (author). “Design of high-resolution photodiode readout circuitry for a bio-implantable continuous glucose sensing chip.” 2012. Masters Thesis, Delft University of Technology. Accessed September 24, 2020. http://resolver.tudelft.nl/uuid:ea9d2e1c-5b03-44e9-b916-587fd737313f.

MLA Handbook (7th Edition):

Kamath, U R (author). “Design of high-resolution photodiode readout circuitry for a bio-implantable continuous glucose sensing chip.” 2012. Web. 24 Sep 2020.

Vancouver:

Kamath UR(. Design of high-resolution photodiode readout circuitry for a bio-implantable continuous glucose sensing chip. [Internet] [Masters thesis]. Delft University of Technology; 2012. [cited 2020 Sep 24]. Available from: http://resolver.tudelft.nl/uuid:ea9d2e1c-5b03-44e9-b916-587fd737313f.

Council of Science Editors:

Kamath UR(. Design of high-resolution photodiode readout circuitry for a bio-implantable continuous glucose sensing chip. [Masters Thesis]. Delft University of Technology; 2012. Available from: http://resolver.tudelft.nl/uuid:ea9d2e1c-5b03-44e9-b916-587fd737313f

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