subject:(schizophrenia)

University of Georgia

1. Moore, Madison Nell. Behavioral changes following daily practice of saccade tasks in schizophrenia.

Degree: BS, Psychology, 2009, University of Georgia

URL: http://purl.galileo.usg.edu/uga_etd/moore_madison_n_200905_bs

► People with schizophrenia show impairment in tasks requiring executive control, like inhibition. A simple test of inhibition is the antisaccade task, which requires a glance… (more)

▼ People with schizophrenia show impairment in tasks requiring executive control, like inhibition. A simple test of inhibition is the antisaccade task, which requires a glance towards the mirror image of a peripheral cue. The goal of this study is to determine how practice on the antisaccade task changes performance on that task and on related tasks known to assess executive control. Participants with schizophrenia and healthy comparison subjects were assigned a single saccade task to practice daily - either antisaccades or prosaccades (glances towards a peripheral cue) - over a two-week period. Executive control was evaluated at pre- and post-test using two tasks: an ocular motor delayed response (ODR) task to measure changes due to practice on a different, but related, saccade task, and the Wisconsin Card Sorting Test (WCST) to evaluate whether changes in executive control could generalize beyond saccade tasks. Preliminary results suggest antisaccade practice resulted in modest antisaccade improvement for both normal and schizophrenia groups. Prosaccade practice did not affect prosaccade performance (due to a ceiling effect in both groups). Over the trials, the normal antisaccade practice group showed improvement across both the saccade specific (ODR) and non-saccade specific (WCST) executive function tasks. The SZ practice groups show little evidence of change across time, with the exception of the SZ antisaccade practice group showing slightly better ODR performance and the SZ prosaccade group perhaps showing a slight decrease in performance on ODR. Initial results from this study suggest that saccadic performance is malleable within certain parameters. Specifically, it appears that behavior (and potentially its neural underpinnings) may be more malleable in healthy people than in people with schizophrenia. Although the gains are modest at this point, it is interesting to observe that practice on one executive function task could potentially be associated with gains on related tasks. This result has implications for aiding or improving behavior and brain function using behavioral training techniques. Advisors/Committee Members: Jennifer McDowell.

Subjects/Keywords: Schizophrenia

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Moore, M. N. (2009). Behavioral changes following daily practice of saccade tasks in schizophrenia. (Thesis). University of Georgia. Retrieved from http://purl.galileo.usg.edu/uga_etd/moore_madison_n_200905_bs

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Moore, Madison Nell. “Behavioral changes following daily practice of saccade tasks in schizophrenia.” 2009. Thesis, University of Georgia. Accessed February 25, 2020. http://purl.galileo.usg.edu/uga_etd/moore_madison_n_200905_bs.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Moore, Madison Nell. “Behavioral changes following daily practice of saccade tasks in schizophrenia.” 2009. Web. 25 Feb 2020.

Vancouver:

Moore MN. Behavioral changes following daily practice of saccade tasks in schizophrenia. [Internet] [Thesis]. University of Georgia; 2009. [cited 2020 Feb 25]. Available from: http://purl.galileo.usg.edu/uga_etd/moore_madison_n_200905_bs.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Moore MN. Behavioral changes following daily practice of saccade tasks in schizophrenia. [Thesis]. University of Georgia; 2009. Available from: http://purl.galileo.usg.edu/uga_etd/moore_madison_n_200905_bs

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Georgia

2. Moore, Madison Nell. Behavioral changes following daily practice of saccade tasks in schizophrenia.

Degree: BS, Psychology, 2009, University of Georgia

URL: http://purl.galileo.usg.edu/uga_etd/moore_madison_n_200905_bs

► People with schizophrenia show impairment in tasks requiring executive control, like inhibition. A simple test of inhibition is the antisaccade task, which requires a glance… (more)

▼ People with schizophrenia show impairment in tasks requiring executive control, like inhibition. A simple test of inhibition is the antisaccade task, which requires a glance towards the mirror image of a peripheral cue. The goal of this study is to determine how practicing the antisaccade task changes performance on that task and on related tasks known to assess executive control. Participants with schizophrenia (SZ) and healthy comparison subjects (NP) were assigned a single saccade task to practice daily - either antisaccades or prosaccades (glances towards a peripheral cue) - over a two-week period. Executive control was evaluated at pre- and post-test using two tasks: an ocular motor delayed response (ODR) task to measure changes due to practice on a different, but related, saccade task, and the Wisconsin Card Sorting Test (WCST) to evaluate whether changes in executive control could generalize beyond saccade tasks. Preliminary results suggest antisaccade practice resulted in modest antisaccade improvement for both NP and SZ groups. Prosaccade practice did not affect prosaccade performance (due to a ceiling effect in both groups). The NP antisaccade practice group showed improvement across both the saccade specific (ODR) and non-saccade specific (WCST) executive function tasks. The SZ practice groups show little evidence of change across time, with the exception of the SZ antisaccade practice group showing slightly better ODR performance and the SZ prosaccade group perhaps showing a slight decrease in performance on ODR. Initial results from this study suggest that saccadic performance is malleable within certain parameters. Specifically, it appears that behavior (and potentially its neural underpinnings) may be more malleable in healthy people than in people with schizophrenia and practice on one executive function task could potentially be associated with modest gains on related tasks. This result has implications for aiding or improving behavior and brain function using behavioral training techniques. Advisors/Committee Members: Jennifer McDowell.

Subjects/Keywords: Schizophrenia

Record Details Similar Records Cite « Share

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Moore, M. N. (2009). Behavioral changes following daily practice of saccade tasks in schizophrenia. (Thesis). University of Georgia. Retrieved from http://purl.galileo.usg.edu/uga_etd/moore_madison_n_200905_bs

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Moore, Madison Nell. “Behavioral changes following daily practice of saccade tasks in schizophrenia.” 2009. Thesis, University of Georgia. Accessed February 25, 2020. http://purl.galileo.usg.edu/uga_etd/moore_madison_n_200905_bs.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Moore, Madison Nell. “Behavioral changes following daily practice of saccade tasks in schizophrenia.” 2009. Web. 25 Feb 2020.

Vancouver:

Moore MN. Behavioral changes following daily practice of saccade tasks in schizophrenia. [Internet] [Thesis]. University of Georgia; 2009. [cited 2020 Feb 25]. Available from: http://purl.galileo.usg.edu/uga_etd/moore_madison_n_200905_bs.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Moore MN. Behavioral changes following daily practice of saccade tasks in schizophrenia. [Thesis]. University of Georgia; 2009. Available from: http://purl.galileo.usg.edu/uga_etd/moore_madison_n_200905_bs

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Georgia

3. Wang, Jun. A specific relationship between motion processing and neural activity deficits in schizophrenia.

Degree: PhD, Psychology, 2009, University of Georgia

URL: http://purl.galileo.usg.edu/uga_etd/wang_jun_200905_phd

► Smooth pursuit abnormalities may reflect motion processing deficits in schizophrenia (SZ). There is little evidence, though, for a link between early neural activity supporting motion… (more)

Subjects/Keywords: Schizophrenia

Record Details Similar Records Cite « Share

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Wang, J. (2009). A specific relationship between motion processing and neural activity deficits in schizophrenia. (Doctoral Dissertation). University of Georgia. Retrieved from http://purl.galileo.usg.edu/uga_etd/wang_jun_200905_phd

Chicago Manual of Style (16^th Edition):

Wang, Jun. “A specific relationship between motion processing and neural activity deficits in schizophrenia.” 2009. Doctoral Dissertation, University of Georgia. Accessed February 25, 2020. http://purl.galileo.usg.edu/uga_etd/wang_jun_200905_phd.

MLA Handbook (7^th Edition):

Wang, Jun. “A specific relationship between motion processing and neural activity deficits in schizophrenia.” 2009. Web. 25 Feb 2020.

Vancouver:

Wang J. A specific relationship between motion processing and neural activity deficits in schizophrenia. [Internet] [Doctoral dissertation]. University of Georgia; 2009. [cited 2020 Feb 25]. Available from: http://purl.galileo.usg.edu/uga_etd/wang_jun_200905_phd.

Council of Science Editors:

Wang J. A specific relationship between motion processing and neural activity deficits in schizophrenia. [Doctoral Dissertation]. University of Georgia; 2009. Available from: http://purl.galileo.usg.edu/uga_etd/wang_jun_200905_phd

University of Georgia

4. Austin, Benjamin Piya. Practice-induced changes in neural circuitries supporting saccade performance in schizophrenia: an fMRI study.

Degree: PhD, Psychology, 2010, University of Georgia

URL: http://purl.galileo.usg.edu/uga_etd/austin_benjamin_p_201008_phd

► Decreased prefrontal cortex (PFC) function is hypothesized as a key deficit in people with schizophrenia. PFC circuitry supports higher level executive control processes such as… (more)

▼ Decreased prefrontal cortex (PFC) function is hypothesized as a key deficit in people with schizophrenia. PFC circuitry supports higher level executive control processes such as inhibition. A simple test of inhibition is provided by an antisaccade task, which requires a glance to the mirror image of a peripheral cue. People with schizophrenia make more antisaccade errors towards the cue and have lower PFC activity than healthy participants. The extent to which PFC activity may be enhanced to possibly improve executive control in schizophrenia is uncertain. Recent studies from our laboratory showed that in healthy people daily antisaccade practice improves antisaccade performance, while daily prosaccade practice disrupts antisaccade performance. These behavioral changes are accompanied by quantifiable changes in brain activation. The current study was designed to determine whether neural pathways supporting antisaccade performance in schizophrenia are modified across time. People with schizophrenia (SZ) and normal comparison subjects (NP) took part in a 2-week trial. Testing evaluated anti- and pro-saccade performance in a 3-Tesla fMRI environment at 3 time points, each separated by a week; 1) Pre-Test, 2) Mid-Test, and 3) Post-Test. Subjects were assigned to a practice group (either antisaccades or prosaccades) and between fMRI testing sessions completed daily practice sessions on the assigned task. In order to determine if improved executive functioning processes could be generalized beyond the practice task, other measures of executive function were evaluated before and after the practice trial using both saccade (ocular motor delayed response task – ODRT) and non-saccade tasks (the Wisconsin Card Sorting Test - WCST). The behavioral results showed that both the SZ and NP prosaccade practice groups demonstrated similar behavioral performance patterns across time (decreased latencies and sustained performance) while the SZ and NP antisaccade practice groups demonstrated incongruent patterns (the SZ group showed a trend for improved antisaccade performance with speed-accuracy tradeoffs while the NP group did not). The imaging results across groups illustrated typical saccadic circuitry in regions known to support antisaccade performance, and all groups demonstrated a trend for decreased PFC across time. Within the schizophrenia group, however, there was a small subset of participants who showed increased PFC activity from pre-test to post-test, and this reversal of hypofrontality was correlated with improved performance on various WCST measurements including, most notably, a decrease in rate of perseverative errors. Advisors/Committee Members: Jennifer McDowell.

Subjects/Keywords: Schizophrenia

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Austin, B. P. (2010). Practice-induced changes in neural circuitries supporting saccade performance in schizophrenia: an fMRI study. (Doctoral Dissertation). University of Georgia. Retrieved from http://purl.galileo.usg.edu/uga_etd/austin_benjamin_p_201008_phd

Chicago Manual of Style (16^th Edition):

Austin, Benjamin Piya. “Practice-induced changes in neural circuitries supporting saccade performance in schizophrenia: an fMRI study.” 2010. Doctoral Dissertation, University of Georgia. Accessed February 25, 2020. http://purl.galileo.usg.edu/uga_etd/austin_benjamin_p_201008_phd.

MLA Handbook (7^th Edition):

Austin, Benjamin Piya. “Practice-induced changes in neural circuitries supporting saccade performance in schizophrenia: an fMRI study.” 2010. Web. 25 Feb 2020.

Vancouver:

Austin BP. Practice-induced changes in neural circuitries supporting saccade performance in schizophrenia: an fMRI study. [Internet] [Doctoral dissertation]. University of Georgia; 2010. [cited 2020 Feb 25]. Available from: http://purl.galileo.usg.edu/uga_etd/austin_benjamin_p_201008_phd.

Council of Science Editors:

Austin BP. Practice-induced changes in neural circuitries supporting saccade performance in schizophrenia: an fMRI study. [Doctoral Dissertation]. University of Georgia; 2010. Available from: http://purl.galileo.usg.edu/uga_etd/austin_benjamin_p_201008_phd

University of Georgia

5. Ethridge, Lauren Elizabeth. Intrinsic and evoked oscillatory brain activity as potential endophenotypes for schizophrenia and psychotic disorders.

Degree: PhD, Neuroscience, 2011, University of Georgia

URL: http://purl.galileo.usg.edu/uga_etd/ethridge_lauren_e_201112_phd

► Evidence for a genetic component for schizophrenia has led to a search for potential endophenotypes that will aid in identifying genetic risk for schizophrenia as… (more)

Subjects/Keywords: schizophrenia

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Ethridge, L. E. (2011). Intrinsic and evoked oscillatory brain activity as potential endophenotypes for schizophrenia and psychotic disorders. (Doctoral Dissertation). University of Georgia. Retrieved from http://purl.galileo.usg.edu/uga_etd/ethridge_lauren_e_201112_phd

Chicago Manual of Style (16^th Edition):

Ethridge, Lauren Elizabeth. “Intrinsic and evoked oscillatory brain activity as potential endophenotypes for schizophrenia and psychotic disorders.” 2011. Doctoral Dissertation, University of Georgia. Accessed February 25, 2020. http://purl.galileo.usg.edu/uga_etd/ethridge_lauren_e_201112_phd.

MLA Handbook (7^th Edition):

Ethridge, Lauren Elizabeth. “Intrinsic and evoked oscillatory brain activity as potential endophenotypes for schizophrenia and psychotic disorders.” 2011. Web. 25 Feb 2020.

Vancouver:

Ethridge LE. Intrinsic and evoked oscillatory brain activity as potential endophenotypes for schizophrenia and psychotic disorders. [Internet] [Doctoral dissertation]. University of Georgia; 2011. [cited 2020 Feb 25]. Available from: http://purl.galileo.usg.edu/uga_etd/ethridge_lauren_e_201112_phd.

Council of Science Editors:

Ethridge LE. Intrinsic and evoked oscillatory brain activity as potential endophenotypes for schizophrenia and psychotic disorders. [Doctoral Dissertation]. University of Georgia; 2011. Available from: http://purl.galileo.usg.edu/uga_etd/ethridge_lauren_e_201112_phd

University of Georgia

6. Boyd, Megan Carly. Schizophrenia and the magnocellular system: a Visual Backward Masking study.

Degree: MS, Psychology, 2007, University of Georgia

URL: http://purl.galileo.usg.edu/uga_etd/boyd_megan_c_200708_ms

► Previous research has shown that the Magnocellular pathway in schizophrenia patients may be hyperactive and may be suppressed using red light. This study uses a… (more)

Subjects/Keywords: Schizophrenia

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Boyd, M. C. (2007). Schizophrenia and the magnocellular system: a Visual Backward Masking study. (Masters Thesis). University of Georgia. Retrieved from http://purl.galileo.usg.edu/uga_etd/boyd_megan_c_200708_ms

Chicago Manual of Style (16^th Edition):

Boyd, Megan Carly. “Schizophrenia and the magnocellular system: a Visual Backward Masking study.” 2007. Masters Thesis, University of Georgia. Accessed February 25, 2020. http://purl.galileo.usg.edu/uga_etd/boyd_megan_c_200708_ms.

MLA Handbook (7^th Edition):

Boyd, Megan Carly. “Schizophrenia and the magnocellular system: a Visual Backward Masking study.” 2007. Web. 25 Feb 2020.

Vancouver:

Boyd MC. Schizophrenia and the magnocellular system: a Visual Backward Masking study. [Internet] [Masters thesis]. University of Georgia; 2007. [cited 2020 Feb 25]. Available from: http://purl.galileo.usg.edu/uga_etd/boyd_megan_c_200708_ms.

Council of Science Editors:

Boyd MC. Schizophrenia and the magnocellular system: a Visual Backward Masking study. [Masters Thesis]. University of Georgia; 2007. Available from: http://purl.galileo.usg.edu/uga_etd/boyd_megan_c_200708_ms

University of Georgia

7. Camchong, Jazmin. Neural correlates of antisaccade and delayed response task performance in participants with schizophrenia and their biological relatives.

Degree: PhD, Psychology, 2007, University of Georgia

URL: http://purl.galileo.usg.edu/uga_etd/camchong_jazmin_200708_phd

► Schizophrenia is characterized by problems with inhibition and working memory. For example, people with schizophrenia show abnormalities on antisaccade (AS) and ocular motor delayed response… (more)

Subjects/Keywords: Schizophrenia

Record Details Similar Records Cite « Share

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Camchong, J. (2007). Neural correlates of antisaccade and delayed response task performance in participants with schizophrenia and their biological relatives. (Doctoral Dissertation). University of Georgia. Retrieved from http://purl.galileo.usg.edu/uga_etd/camchong_jazmin_200708_phd

Chicago Manual of Style (16^th Edition):

Camchong, Jazmin. “Neural correlates of antisaccade and delayed response task performance in participants with schizophrenia and their biological relatives.” 2007. Doctoral Dissertation, University of Georgia. Accessed February 25, 2020. http://purl.galileo.usg.edu/uga_etd/camchong_jazmin_200708_phd.

MLA Handbook (7^th Edition):

Camchong, Jazmin. “Neural correlates of antisaccade and delayed response task performance in participants with schizophrenia and their biological relatives.” 2007. Web. 25 Feb 2020.

Vancouver:

Camchong J. Neural correlates of antisaccade and delayed response task performance in participants with schizophrenia and their biological relatives. [Internet] [Doctoral dissertation]. University of Georgia; 2007. [cited 2020 Feb 25]. Available from: http://purl.galileo.usg.edu/uga_etd/camchong_jazmin_200708_phd.

Council of Science Editors:

Camchong J. Neural correlates of antisaccade and delayed response task performance in participants with schizophrenia and their biological relatives. [Doctoral Dissertation]. University of Georgia; 2007. Available from: http://purl.galileo.usg.edu/uga_etd/camchong_jazmin_200708_phd

University of Georgia

8. Gilmore, Casey Steven. Is faster always better?: rate of stimulation affects auditory-evoked responses in schizophrenia.

Degree: PhD, Psychology, 2007, University of Georgia

URL: http://purl.galileo.usg.edu/uga_etd/gilmore_casey_s_200712_phd

► Schizophrenia patients exhibit characteristic problems in early stages of auditory information processing, which may be related to cognitive dysfunction present in the illness. These problems… (more)

▼ Schizophrenia patients exhibit characteristic problems in early stages of auditory information processing, which may be related to cognitive dysfunction present in the illness. These problems are related to schizophrenia patients’ inherent inability to generate and/or maintain evoked oscillatory rhythms in response to both transient and repetitive (steady-state) stimuli. These oscillatory rhythms underlie cortical middle- and late-latency auditory evoked responses (MLAERs), P1 and N1, and evoked oscillatory responses at the driving frequency of steady-state stimuli (SSRs). These evoked responses are indices of abnormal sensory encoding and temporal integration ability in schizophrenia. These abnormalities may be attributed to some fundamental characteristics of schizophrenia patients' auditory systems - characteristics whose sum effect is to reduce the signal-to-noise ratio during auditory information processing. The present study examined the hypothesis that increasing the rate of stimulation, i.e. increasing the number of stimuli presented per unit time, would increase signal power sufficiently to normalize evoked oscillatory responses in schizophrenia patients. Steady-state stimuli at various rates (5, 20, 40, 80, and 160 Hz) were presented to 12 normal and 12 schizophrenia subjects while 248 sensor whole-cortex magnetoencephalography was recorded. The FFT power and inter-trial phase coherence in the delta and theta bands underlying MLAERs and in the SSRs at the driving frequencies of the respective rates of stimulation were examined for differences between groups, hemispheres, and rates of stimulation. Results indicated that schizophrenia patients were able to generate essentially normal steady-state responses in response to stimuli with durations sufficiently long enough to allow build-up of the SSR. Steady-state stimuli may also enhance patients’ auditory integration and encoding abilities, perhaps through increased signal strength, as indicated by a lack of schizophrenia-normal differences on low-frequency evoked oscillations subserving the P1 and N1 MLAERs. Finally, the observation that evoked power and inter-trial phase coherence play divergent but complementary roles with regard to MLAER-associated low-frequency evoked oscillatory activity in both normal and schizophrenia subjects was illustrated. Understanding the mechanisms responsible for deficits in the ability to evoke oscillatory responses could help in understanding the relationship between the neuropathology and symptoms of schizophrenia. Advisors/Committee Members: Brett Clementz.

Subjects/Keywords: Schizophrenia

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Gilmore, C. S. (2007). Is faster always better?: rate of stimulation affects auditory-evoked responses in schizophrenia. (Doctoral Dissertation). University of Georgia. Retrieved from http://purl.galileo.usg.edu/uga_etd/gilmore_casey_s_200712_phd

Chicago Manual of Style (16^th Edition):

Gilmore, Casey Steven. “Is faster always better?: rate of stimulation affects auditory-evoked responses in schizophrenia.” 2007. Doctoral Dissertation, University of Georgia. Accessed February 25, 2020. http://purl.galileo.usg.edu/uga_etd/gilmore_casey_s_200712_phd.

MLA Handbook (7^th Edition):

Gilmore, Casey Steven. “Is faster always better?: rate of stimulation affects auditory-evoked responses in schizophrenia.” 2007. Web. 25 Feb 2020.

Vancouver:

Gilmore CS. Is faster always better?: rate of stimulation affects auditory-evoked responses in schizophrenia. [Internet] [Doctoral dissertation]. University of Georgia; 2007. [cited 2020 Feb 25]. Available from: http://purl.galileo.usg.edu/uga_etd/gilmore_casey_s_200712_phd.

Council of Science Editors:

Gilmore CS. Is faster always better?: rate of stimulation affects auditory-evoked responses in schizophrenia. [Doctoral Dissertation]. University of Georgia; 2007. Available from: http://purl.galileo.usg.edu/uga_etd/gilmore_casey_s_200712_phd

University of Georgia

9. Herman, Elizabeth Joan. The central cholinergic system as a therapeutic target for the cognitive dysfunction of schizophrenia.

Degree: PhD, Pharmacology, 2007, University of Georgia

URL: http://purl.galileo.usg.edu/uga_etd/herman_elizabeth_j_200712_phd

► Schizophrenia is characterized by three core symptoms: positive, negative and cognitive dysfunction, the latter symptom is best correlated with long term functional outcome. While most… (more)

▼ Schizophrenia is characterized by three core symptoms: positive, negative and cognitive dysfunction, the latter symptom is best correlated with long term functional outcome. While most studies related to schizophrenia (including those related to cognitive function) have focused on abnormalities in the neurotransmitters, dopamine, serotonin and glutamate, there is also evidence that acetylcholine neurotransmission (i.e., central cholinergic function) is altered in the illness. Thus, the central cholinergic system could serve as a therapeutic target for improving cognition in schizophrenia. In the evaluation of two commonly used AChEIs for effects on sensorimotor gating in an experimental animal model, galantamine (depending on dose) improved PPI deficits in three pharmacologic models of PPI impairment, whereas donepezil ameliorated PPI deficits induced by scopolamine and apomorphine, but was not effective in the MK801 model. In radial arm maze experiments neither haloperidol nor risperidone affected win-shift acquisition although DNMTP performance was modestly impaired at the longer delays by risperidone. Haloperidol, but not risperidone, impaired water maze hidden platform acquisition as well as probe trial performance possibly due to psychomotor impairments and elevated levels of anxiety. In 5CSRTT experiments haloperidol and, to a lesser degree, risperidone, impaired task acquisition as indicated by the failure (or increase in the number of trials) to meet specific performance criteria. Results from these behavior experiments indicate task dependent and temporal effects of exposure to therapeutic doses of haloperidol and risperidone and risperidone may impair spatial working and short-term memory as the demands of the task increase. Haloperidol and risperidone were without significant effect in the ELISA experiments which were conducted to detect potential (antipsychotic-related) alterations in the levels of VAChT and α7 nAChR in medial prefrontal cortex of rats treated for 320 days. Advisors/Committee Members: Alvin V. Terry.

Subjects/Keywords: Schizophrenia

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Herman, E. J. (2007). The central cholinergic system as a therapeutic target for the cognitive dysfunction of schizophrenia. (Doctoral Dissertation). University of Georgia. Retrieved from http://purl.galileo.usg.edu/uga_etd/herman_elizabeth_j_200712_phd

Chicago Manual of Style (16^th Edition):

Herman, Elizabeth Joan. “The central cholinergic system as a therapeutic target for the cognitive dysfunction of schizophrenia.” 2007. Doctoral Dissertation, University of Georgia. Accessed February 25, 2020. http://purl.galileo.usg.edu/uga_etd/herman_elizabeth_j_200712_phd.

MLA Handbook (7^th Edition):

Herman, Elizabeth Joan. “The central cholinergic system as a therapeutic target for the cognitive dysfunction of schizophrenia.” 2007. Web. 25 Feb 2020.

Vancouver:

Herman EJ. The central cholinergic system as a therapeutic target for the cognitive dysfunction of schizophrenia. [Internet] [Doctoral dissertation]. University of Georgia; 2007. [cited 2020 Feb 25]. Available from: http://purl.galileo.usg.edu/uga_etd/herman_elizabeth_j_200712_phd.

Council of Science Editors:

Herman EJ. The central cholinergic system as a therapeutic target for the cognitive dysfunction of schizophrenia. [Doctoral Dissertation]. University of Georgia; 2007. Available from: http://purl.galileo.usg.edu/uga_etd/herman_elizabeth_j_200712_phd

University of Hawaii – Manoa

10. Smith, Shana Golembo. Multivariate prediction of schizophrenia in adulthood utilizing childhood neurological data.

Degree: 2016, University of Hawaii – Manoa

URL: http://hdl.handle.net/10125/101029

►

Ph.D. University of Hawaii at Manoa 2012.

Research has highlighted numerous benefits of identifying at-risk individuals before they develop schizophrenia. Longitudinal studies have elucidated a… (more)

Subjects/Keywords: schizophrenia

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APA (6^th Edition):

Smith, S. G. (2016). Multivariate prediction of schizophrenia in adulthood utilizing childhood neurological data. (Thesis). University of Hawaii – Manoa. Retrieved from http://hdl.handle.net/10125/101029

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Smith, Shana Golembo. “Multivariate prediction of schizophrenia in adulthood utilizing childhood neurological data.” 2016. Thesis, University of Hawaii – Manoa. Accessed February 25, 2020. http://hdl.handle.net/10125/101029.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Smith, Shana Golembo. “Multivariate prediction of schizophrenia in adulthood utilizing childhood neurological data.” 2016. Web. 25 Feb 2020.

Vancouver:

Smith SG. Multivariate prediction of schizophrenia in adulthood utilizing childhood neurological data. [Internet] [Thesis]. University of Hawaii – Manoa; 2016. [cited 2020 Feb 25]. Available from: http://hdl.handle.net/10125/101029.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Smith SG. Multivariate prediction of schizophrenia in adulthood utilizing childhood neurological data. [Thesis]. University of Hawaii – Manoa; 2016. Available from: http://hdl.handle.net/10125/101029

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Hong Kong

11. 巫崇榆; Mo, Sung-yu, Chloe. Pilot study : effectiveness of integrated social skills training (ISST) with social cognition component for people with schizophrenia : a clinical control trial.

Degree: Master of Psychological Medicine, 2013, University of Hong Kong

URL: Mo, S. C. [巫崇榆]. (2013). Pilot study : effectiveness of integrated social skills training (ISST) with social cognition component for people with schizophrenia : a clinical control trial. (Thesis). University of Hong Kong, Pokfulam, Hong Kong SAR. Retrieved from http://dx.doi.org/10.5353/th_b5088217 ; http://dx.doi.org/10.5353/th_b5088217 ; http://hdl.handle.net/10722/192978

►

Social skills deficit has been a long-standing functional impairment among people with Schizophrenia. This pervasive problem affects multiple aspects in life. Most interventions focus on… (more)

▼

Social skills deficit has been a long-standing functional impairment among people with Schizophrenia. This pervasive problem affects multiple aspects in life. Most interventions focus on the enhancement of expressive social skills; in the contrary, receptive social skills are less emphasized. However, receptive skills such as social intelligence and theory of mind (ToM) are the pre-requisites and foundation of expressive skills. Researches also suggested that people with schizophrenia have various extent of impairment in social cognition, i.e. receptive skills. Incorporation of receptive skills modules into convention intervention may be effective to enhance overall social and occupational performance. The Integrated Social Skill Training (ISST) is a hybrid intervention introducing social cognition components into convention skills training model. The effectiveness on the mental state, and social occupational function was evaluated through a pilot study. 12 Subjects were recruited in a local psychiatric day training unit and were divided into control and experimental group. The experimental group went through the 8-sessions ISST on top of day training; while control group were put on the waiting list and received purely day training within the research period. Psychopathology was measured with Positive and Negative Syndrome Scale (PANSS) and the level of social and occupational functions was measured by Social and Occupational Functioning Assessment Scale (SOFAS). Measurements were taken before and after the administration of ISST on both groups of subjects. Repeated measures ANOVA and paired samples t-test were used for between-group and within-group data analysis respectively. Results suggested a neutral effect of ISST to mental states; whereas a positive effect of ISST was reported on improving the social occupational performance for subjects within the experimental group but not within the control group. However, the magnitude of improvement was yet to meet a statistical difference when compared with that of the control group. By incorporating social cognition elements into convention skills training model can improve the social and occupational performance of people with schizophrenia. Further refinement of the ISST is to be made to achieve a higher efficacy.

published_or_final_version

Psychological Medicine

Master

Master of Psychological Medicine

Subjects/Keywords: Schizophrenia

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APA (6^th Edition):

巫崇榆; Mo, Sung-yu, C. (2013). Pilot study : effectiveness of integrated social skills training (ISST) with social cognition component for people with schizophrenia : a clinical control trial. (Masters Thesis). University of Hong Kong. Retrieved from Mo, S. C. [巫崇榆]. (2013). Pilot study : effectiveness of integrated social skills training (ISST) with social cognition component for people with schizophrenia : a clinical control trial. (Thesis). University of Hong Kong, Pokfulam, Hong Kong SAR. Retrieved from http://dx.doi.org/10.5353/th_b5088217 ; http://dx.doi.org/10.5353/th_b5088217 ; http://hdl.handle.net/10722/192978

Chicago Manual of Style (16^th Edition):

巫崇榆; Mo, Sung-yu, Chloe. “Pilot study : effectiveness of integrated social skills training (ISST) with social cognition component for people with schizophrenia : a clinical control trial.” 2013. Masters Thesis, University of Hong Kong. Accessed February 25, 2020. Mo, S. C. [巫崇榆]. (2013). Pilot study : effectiveness of integrated social skills training (ISST) with social cognition component for people with schizophrenia : a clinical control trial. (Thesis). University of Hong Kong, Pokfulam, Hong Kong SAR. Retrieved from http://dx.doi.org/10.5353/th_b5088217 ; http://dx.doi.org/10.5353/th_b5088217 ; http://hdl.handle.net/10722/192978.

MLA Handbook (7^th Edition):

巫崇榆; Mo, Sung-yu, Chloe. “Pilot study : effectiveness of integrated social skills training (ISST) with social cognition component for people with schizophrenia : a clinical control trial.” 2013. Web. 25 Feb 2020.

Vancouver:

巫崇榆; Mo, Sung-yu C. Pilot study : effectiveness of integrated social skills training (ISST) with social cognition component for people with schizophrenia : a clinical control trial. [Internet] [Masters thesis]. University of Hong Kong; 2013. [cited 2020 Feb 25]. Available from: Mo, S. C. [巫崇榆]. (2013). Pilot study : effectiveness of integrated social skills training (ISST) with social cognition component for people with schizophrenia : a clinical control trial. (Thesis). University of Hong Kong, Pokfulam, Hong Kong SAR. Retrieved from http://dx.doi.org/10.5353/th_b5088217 ; http://dx.doi.org/10.5353/th_b5088217 ; http://hdl.handle.net/10722/192978.

Council of Science Editors:

巫崇榆; Mo, Sung-yu C. Pilot study : effectiveness of integrated social skills training (ISST) with social cognition component for people with schizophrenia : a clinical control trial. [Masters Thesis]. University of Hong Kong; 2013. Available from: Mo, S. C. [巫崇榆]. (2013). Pilot study : effectiveness of integrated social skills training (ISST) with social cognition component for people with schizophrenia : a clinical control trial. (Thesis). University of Hong Kong, Pokfulam, Hong Kong SAR. Retrieved from http://dx.doi.org/10.5353/th_b5088217 ; http://dx.doi.org/10.5353/th_b5088217 ; http://hdl.handle.net/10722/192978

Penn State University

12. Zhou, Yijing. Interactome analysis reveals ZNF804A, a schizophrenia risk gene, as a novel component of protein translational machinery critical for embryonic neurodevelopment.

Degree: 2018, Penn State University

URL: https://etda.libraries.psu.edu/catalog/14925yxz167

► Schizophrenia (SCZ) is a chronic, debilitating mental disorder that affects approximately 1% of the population. The symptoms of SCZ fall into three categories: positive, negative,… (more)

▼ Schizophrenia (SCZ) is a chronic, debilitating mental disorder that affects approximately 1% of the population. The symptoms of SCZ fall into three categories: positive, negative, and cognitive. Current understanding attributes SCZ to both genetic and environmental determinants, supported by clinical and experimental evidence. Earlier genetic studies of SCZ have focused on monogenetic factors and family studies. Entering the new millennium, genome-wide association studies (GWASs) started to be used to find the disease-associated loci on the meta-genomic scale.Single nucleotide polymorphism (SNP) rs1344706, localized in the gene ZNF804A, was the first SNP identified to achieve genome-wide significance for psychosis. Several follow-up GWASs have validated the association of rs1344706 with SCZ and other psychosis in different populations. Although the association with SCZ has been reported since 2008, the molecular function of ZNF804A remains largely unclear. In our study, we found that ZFP804A (the rodent homolog of ZNF804A) expression is high in the embryonic mouse brain but decreased in the adulthood. We proved that proper expression level of ZFP804A is essential for normal neuronal migration. We also noticed decreased neural progenitor cell (NPC) proliferation and differentiation caused by insufficient ZFP804A. To unbiasedly elucidate its molecular functions, we conducted a yeast two-hybrid (Y2H) screening and identified novel proteins that interact with ZNF804A. The gene ontology (GO) enrichment analysis revealed two major functions of ZNF804A interacting proteins: cellular adhesion/cytoskeleton regulation and translation control. In sucrose gradient fractionation assay, ZNF804A co-fractionates with translational machinery and modulates the translational efficiency potentially through the mechanistic target of rapamycin (mTOR) pathway. Using Duolink proximity ligation assay (PLA), we confirmed the interaction between ZNF804A and ribosomal protein SA (RPSA). A proper level of RPSA is critical for optimal translation efficiency. Overexpression of RPSA rescues the migration and translation defects caused by Zfp804a knockdown. On the other hand, RPSA also serves as a receptor for laminin and presence of laminin in the extracellular matrix (ECM) augments the interaction between RPSA and ZNF804A. This implies that the function of ZNF804A might be regulated by extracellular cues.In addition, ZFP804A target RNA was identified with RNA-immunoprecipitation - RNA sequencing (RIP-seq). ZFP804A is physically associated with transcripts involved in ribosomal and mitochondrial functions. This suggests that ZFP804A might regulate translation through multiple mechanisms: direct involvement as a part of translational machinery; indirect contribution by regulating the expression level of other components of translational machinery. The role of ZNF804A in regulating translation efficiency of target transcripts is confirmed by Duolink PLA. Among the ZNF804A bound transcripts, neurogranin (Nrgn) has been associated with SCZ in previous… Advisors/Committee Members: Yingwei Mao, Dissertation Advisor.

Subjects/Keywords: schizophrenia

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Zhou, Y. (2018). Interactome analysis reveals ZNF804A, a schizophrenia risk gene, as a novel component of protein translational machinery critical for embryonic neurodevelopment. (Thesis). Penn State University. Retrieved from https://etda.libraries.psu.edu/catalog/14925yxz167

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Zhou, Yijing. “Interactome analysis reveals ZNF804A, a schizophrenia risk gene, as a novel component of protein translational machinery critical for embryonic neurodevelopment.” 2018. Thesis, Penn State University. Accessed February 25, 2020. https://etda.libraries.psu.edu/catalog/14925yxz167.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Zhou, Yijing. “Interactome analysis reveals ZNF804A, a schizophrenia risk gene, as a novel component of protein translational machinery critical for embryonic neurodevelopment.” 2018. Web. 25 Feb 2020.

Vancouver:

Zhou Y. Interactome analysis reveals ZNF804A, a schizophrenia risk gene, as a novel component of protein translational machinery critical for embryonic neurodevelopment. [Internet] [Thesis]. Penn State University; 2018. [cited 2020 Feb 25]. Available from: https://etda.libraries.psu.edu/catalog/14925yxz167.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Zhou Y. Interactome analysis reveals ZNF804A, a schizophrenia risk gene, as a novel component of protein translational machinery critical for embryonic neurodevelopment. [Thesis]. Penn State University; 2018. Available from: https://etda.libraries.psu.edu/catalog/14925yxz167

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Victoria

13. Sheer, Jeffrey Brian. Keeping track of your inner voice: an exploration of speech-monitoring deficits in schizophrenia.

Degree: Department of Psychology, 2017, University of Victoria

URL: http://hdl.handle.net/1828/8002

► During the last 20 years, a body of research has emerged suggesting that deficits in the self-monitoring of willed intention to act may be responsible… (more)

▼ During the last 20 years, a body of research has emerged suggesting that deficits in the self-monitoring of willed intention to act may be responsible for the expression of positive symptoms in schizophrenia (Frith, 1992). Empirical evidence supporting this theory indicates that schizophrenics with positive symptoms are impaired on motor and speech based tasks that involve monitoring of internal cognitive mechanisms and behavior plans, but are less impaired when monitoring external sensory feedback. The current project extends this research by comparing the performance of two groups of schizophrenics (hallucinators, n=16; and nonhallucinators, n=15) with a group of nonpsychotic psychiatric patients (n = 15) on measures of speech monitoring of internal and overt speech. On two measures of internal speech monitoring (silent reading and identification of speech errors in a white noise environment), the schizophrenics were found to be impaired relative to controls; however, the schizophrenics were also impaired on a task of self-monitoring when they had access to external feedback. Analysis of the subgroups data (hallucinators vs. nonhallucinators) indicated very similar performances across tests and no significant differences were identified, with the exception of the silent reading test in which the hallucinators did perform significantly worse. These results indicate that the speech-monitoring deficit in schizophrenia is not limited to the internal speech plan, but can also involve a failure to monitor overt speech, contrary to previous report. Furthermore, speech-monitoring deficits are not limited to schizophrenics who experience hallucinations. An additional experiment involving delayed auditory feedback (DAF) was also conducted to replicate a previous finding in the literature that schizophrenics were more dysfluent in DAF. On the DAF task, the combined schizophrenic group were found to be more dysfluent than controls, and there were no differences between the two schizophrenic subgroups. Further correlational analysis revealed a strong relationship between the level of dysfluency in DAF and self-monitoring impairment. While the results of the experiment were similar to those found by previous authors (Goldberg, Gold, Coppola, & Weinberger, 1997), the correlational analysis allows for an explanation of dysfluency in DAF based on self-monitoring. Advisors/Committee Members: Mateer, Catherine A. (supervisor).

Subjects/Keywords: Schizophrenia

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APA (6^th Edition):

Sheer, J. B. (2017). Keeping track of your inner voice: an exploration of speech-monitoring deficits in schizophrenia. (Thesis). University of Victoria. Retrieved from http://hdl.handle.net/1828/8002

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Sheer, Jeffrey Brian. “Keeping track of your inner voice: an exploration of speech-monitoring deficits in schizophrenia.” 2017. Thesis, University of Victoria. Accessed February 25, 2020. http://hdl.handle.net/1828/8002.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Sheer, Jeffrey Brian. “Keeping track of your inner voice: an exploration of speech-monitoring deficits in schizophrenia.” 2017. Web. 25 Feb 2020.

Vancouver:

Sheer JB. Keeping track of your inner voice: an exploration of speech-monitoring deficits in schizophrenia. [Internet] [Thesis]. University of Victoria; 2017. [cited 2020 Feb 25]. Available from: http://hdl.handle.net/1828/8002.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Sheer JB. Keeping track of your inner voice: an exploration of speech-monitoring deficits in schizophrenia. [Thesis]. University of Victoria; 2017. Available from: http://hdl.handle.net/1828/8002

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Clemson University

14. Montoya, Natalie. Use of Evidence-Based Practice in Recreational Therapy Programs for Schizophrenia Spectrum Disorder (SSD) Recovery: A Descriptive Study.

Degree: MS, Parks, Recreation and Tourism Management, 2018, Clemson University

URL: https://tigerprints.clemson.edu/all_theses/2865

► Schizophrenia Spectrum Disorder (SSD) is a mental illness that currently has no cure, however, with the use of pharmaceutical and psychosocial treatments, such as Recreational… (more)

Subjects/Keywords: Schizophrenia

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APA (6^th Edition):

Montoya, N. (2018). Use of Evidence-Based Practice in Recreational Therapy Programs for Schizophrenia Spectrum Disorder (SSD) Recovery: A Descriptive Study. (Masters Thesis). Clemson University. Retrieved from https://tigerprints.clemson.edu/all_theses/2865

Chicago Manual of Style (16^th Edition):

Montoya, Natalie. “Use of Evidence-Based Practice in Recreational Therapy Programs for Schizophrenia Spectrum Disorder (SSD) Recovery: A Descriptive Study.” 2018. Masters Thesis, Clemson University. Accessed February 25, 2020. https://tigerprints.clemson.edu/all_theses/2865.

MLA Handbook (7^th Edition):

Montoya, Natalie. “Use of Evidence-Based Practice in Recreational Therapy Programs for Schizophrenia Spectrum Disorder (SSD) Recovery: A Descriptive Study.” 2018. Web. 25 Feb 2020.

Vancouver:

Montoya N. Use of Evidence-Based Practice in Recreational Therapy Programs for Schizophrenia Spectrum Disorder (SSD) Recovery: A Descriptive Study. [Internet] [Masters thesis]. Clemson University; 2018. [cited 2020 Feb 25]. Available from: https://tigerprints.clemson.edu/all_theses/2865.

Council of Science Editors:

Montoya N. Use of Evidence-Based Practice in Recreational Therapy Programs for Schizophrenia Spectrum Disorder (SSD) Recovery: A Descriptive Study. [Masters Thesis]. Clemson University; 2018. Available from: https://tigerprints.clemson.edu/all_theses/2865

Universidad de Cantabria

15. Pazos del Olmo, Cristina. Antipsychotic mediated changes in CNTNAP3 gene expression in SK-N-SH cells.

Degree: Máster en Iniciación a la Investigación en Salud Mental, 2015, Universidad de Cantabria

URL: http://hdl.handle.net/10902/7662

► Introduction. Schizophrenia is one of the most common and severe psychotic disorders of all. A growing number of researchers understand the need of genetic studies… (more)

Subjects/Keywords: Schizophrenia

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APA (6^th Edition):

Pazos del Olmo, C. (2015). Antipsychotic mediated changes in CNTNAP3 gene expression in SK-N-SH cells. (Masters Thesis). Universidad de Cantabria. Retrieved from http://hdl.handle.net/10902/7662

Chicago Manual of Style (16^th Edition):

Pazos del Olmo, Cristina. “Antipsychotic mediated changes in CNTNAP3 gene expression in SK-N-SH cells.” 2015. Masters Thesis, Universidad de Cantabria. Accessed February 25, 2020. http://hdl.handle.net/10902/7662.

MLA Handbook (7^th Edition):

Pazos del Olmo, Cristina. “Antipsychotic mediated changes in CNTNAP3 gene expression in SK-N-SH cells.” 2015. Web. 25 Feb 2020.

Vancouver:

Pazos del Olmo C. Antipsychotic mediated changes in CNTNAP3 gene expression in SK-N-SH cells. [Internet] [Masters thesis]. Universidad de Cantabria; 2015. [cited 2020 Feb 25]. Available from: http://hdl.handle.net/10902/7662.

Council of Science Editors:

Pazos del Olmo C. Antipsychotic mediated changes in CNTNAP3 gene expression in SK-N-SH cells. [Masters Thesis]. Universidad de Cantabria; 2015. Available from: http://hdl.handle.net/10902/7662

University of Tasmania

16. Urie, Rebecca. The efficacy of massage therapy for people with schizophrenia.

Degree: 2012, University of Tasmania

URL: https://eprints.utas.edu.au/22291/1/whole_UrieRebecca2012_thesis.pdf

► This literature review examines evidence regarding the likely efficacy of massage therapy for people with schizophrenia and is placed in context by reviewing the past… (more)

Subjects/Keywords: Schizophrenia; Schizophrenia; Schizophrenia; Massage therapy.

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APA (6^th Edition):

Urie, R. (2012). The efficacy of massage therapy for people with schizophrenia. (Thesis). University of Tasmania. Retrieved from https://eprints.utas.edu.au/22291/1/whole_UrieRebecca2012_thesis.pdf

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Urie, Rebecca. “The efficacy of massage therapy for people with schizophrenia.” 2012. Thesis, University of Tasmania. Accessed February 25, 2020. https://eprints.utas.edu.au/22291/1/whole_UrieRebecca2012_thesis.pdf.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Urie, Rebecca. “The efficacy of massage therapy for people with schizophrenia.” 2012. Web. 25 Feb 2020.

Vancouver:

Urie R. The efficacy of massage therapy for people with schizophrenia. [Internet] [Thesis]. University of Tasmania; 2012. [cited 2020 Feb 25]. Available from: https://eprints.utas.edu.au/22291/1/whole_UrieRebecca2012_thesis.pdf.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Urie R. The efficacy of massage therapy for people with schizophrenia. [Thesis]. University of Tasmania; 2012. Available from: https://eprints.utas.edu.au/22291/1/whole_UrieRebecca2012_thesis.pdf

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Rutgers University

17. Ramirez, Carmen, 1984-. Evaluation of two NOS1AP regulatory variants and NOS1 as a candidate gene contributing to schizophrenia risk.

Degree: MS, Microbiology and Molecular Genetics, 2013, Rutgers University

URL: https://rucore.libraries.rutgers.edu/rutgers-lib/41904/

► Schizophrenia is a major neuropsychiatric disorder that affects approximately one percent of the general population. Although the etiology of schizophrenia is unknown, family, twin and… (more)

▼ Schizophrenia is a major neuropsychiatric disorder that affects approximately one percent of the general population. Although the etiology of schizophrenia is unknown, family, twin and adoption studies have demonstrated that schizophrenia is a predominantly genetic disorder with a very high heritability. We previously reported highly significant evidence of linkage to chromosome 1q21-23, identified NOS1AP as the candidate gene from this region contributing to risk for schizophrenia in our sample, and identified three SNPs with strong evidence of association to schizophrenia. These SNPs were tested for regulatory functions using a Dual Luciferase Reporter Assay. rs12742393 demonstrated regulatory activity and produced significant allelic expression differences in two different human neural cell lines. Further statistical analysis of eight SNPs in strong LD with rs12742393 identified a haplotype block of four SNPs in complete LD with each other (rs4557949-rs11584803-rs4145621-rs12084492) with strong evidence of association to schizophrenia. Additional statistical analysis revealed that a haplotype of rs12742393 and this block produced stronger evidence for association than rs12742393 alone. rs4145621 already has been tested for regulatory activity and produced no evidence of being a functional variant. The focus of this thesis was to evaluate the regulatory activity of two of these SNPs within this haplotype, rs12084492 and rs4557949. We performed Dual-Luciferase Reporter Assays to test for regulatory function of each SNP individually and in combination with rs12742393 using two different cell lines, PFSK-1 and SK-N-MC, and using different cell confluence levels. Our results suggest that both SNPs are not functional variants. Evaluation of rs11584803 is necessary to completely test our initial hypothesis. Advisors/Committee Members: Brzustowicz, Linda M (chair), Firestein, Bonnie L (internal member), Millonig, James H (internal member), Buyske, Steve (internal member).

Subjects/Keywords: Schizophrenia – Genetic aspects; Schizophrenia – Etiology

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APA (6^th Edition):

Ramirez, Carmen, 1. (2013). Evaluation of two NOS1AP regulatory variants and NOS1 as a candidate gene contributing to schizophrenia risk. (Masters Thesis). Rutgers University. Retrieved from https://rucore.libraries.rutgers.edu/rutgers-lib/41904/

Chicago Manual of Style (16^th Edition):

Ramirez, Carmen, 1984-. “Evaluation of two NOS1AP regulatory variants and NOS1 as a candidate gene contributing to schizophrenia risk.” 2013. Masters Thesis, Rutgers University. Accessed February 25, 2020. https://rucore.libraries.rutgers.edu/rutgers-lib/41904/.

MLA Handbook (7^th Edition):

Ramirez, Carmen, 1984-. “Evaluation of two NOS1AP regulatory variants and NOS1 as a candidate gene contributing to schizophrenia risk.” 2013. Web. 25 Feb 2020.

Vancouver:

Ramirez, Carmen 1. Evaluation of two NOS1AP regulatory variants and NOS1 as a candidate gene contributing to schizophrenia risk. [Internet] [Masters thesis]. Rutgers University; 2013. [cited 2020 Feb 25]. Available from: https://rucore.libraries.rutgers.edu/rutgers-lib/41904/.

Council of Science Editors:

Ramirez, Carmen 1. Evaluation of two NOS1AP regulatory variants and NOS1 as a candidate gene contributing to schizophrenia risk. [Masters Thesis]. Rutgers University; 2013. Available from: https://rucore.libraries.rutgers.edu/rutgers-lib/41904/

University of Edinburgh

18. Welch, Killian. Amygdala volume in a cognitively impaired population at enhanced risk of schizophrenia.

Degree: 2008, University of Edinburgh

URL: http://hdl.handle.net/1842/2681

► It is established that the mildly learning disabled population has a three fold elevated risk for schizophrenia. On the basis of findings from previous neuroimaging… (more)

Subjects/Keywords: Psychiatry; schizophrenia

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APA (6^th Edition):

Welch, K. (2008). Amygdala volume in a cognitively impaired population at enhanced risk of schizophrenia. (Thesis). University of Edinburgh. Retrieved from http://hdl.handle.net/1842/2681

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Welch, Killian. “Amygdala volume in a cognitively impaired population at enhanced risk of schizophrenia.” 2008. Thesis, University of Edinburgh. Accessed February 25, 2020. http://hdl.handle.net/1842/2681.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Welch, Killian. “Amygdala volume in a cognitively impaired population at enhanced risk of schizophrenia.” 2008. Web. 25 Feb 2020.

Vancouver:

Welch K. Amygdala volume in a cognitively impaired population at enhanced risk of schizophrenia. [Internet] [Thesis]. University of Edinburgh; 2008. [cited 2020 Feb 25]. Available from: http://hdl.handle.net/1842/2681.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Welch K. Amygdala volume in a cognitively impaired population at enhanced risk of schizophrenia. [Thesis]. University of Edinburgh; 2008. Available from: http://hdl.handle.net/1842/2681

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Georgia

19. Bedwell, Jeffrey Scott. Accelerated age-related decline of visual processing in healthy first-degree relatives of persons with schizophrenia.

Degree: MS, Psychology, 2001, University of Georgia

URL: http://purl.galileo.usg.edu/uga_etd/bedwell_jeffrey_s_200112_ms

► Research focusing on individuals with schizophrenia has noted that a subgroup evidence an accelerated age-related decline in general cognitive performance, particularly on tasks that emphasize… (more)

Subjects/Keywords: Schizophrenia

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APA (6^th Edition):

Bedwell, J. S. (2001). Accelerated age-related decline of visual processing in healthy first-degree relatives of persons with schizophrenia. (Masters Thesis). University of Georgia. Retrieved from http://purl.galileo.usg.edu/uga_etd/bedwell_jeffrey_s_200112_ms

Chicago Manual of Style (16^th Edition):

Bedwell, Jeffrey Scott. “Accelerated age-related decline of visual processing in healthy first-degree relatives of persons with schizophrenia.” 2001. Masters Thesis, University of Georgia. Accessed February 25, 2020. http://purl.galileo.usg.edu/uga_etd/bedwell_jeffrey_s_200112_ms.

MLA Handbook (7^th Edition):

Bedwell, Jeffrey Scott. “Accelerated age-related decline of visual processing in healthy first-degree relatives of persons with schizophrenia.” 2001. Web. 25 Feb 2020.

Vancouver:

Bedwell JS. Accelerated age-related decline of visual processing in healthy first-degree relatives of persons with schizophrenia. [Internet] [Masters thesis]. University of Georgia; 2001. [cited 2020 Feb 25]. Available from: http://purl.galileo.usg.edu/uga_etd/bedwell_jeffrey_s_200112_ms.

Council of Science Editors:

Bedwell JS. Accelerated age-related decline of visual processing in healthy first-degree relatives of persons with schizophrenia. [Masters Thesis]. University of Georgia; 2001. Available from: http://purl.galileo.usg.edu/uga_etd/bedwell_jeffrey_s_200112_ms

University of Georgia

20. Ganguly, Rahul. Antipsychotic polypharmacy vs. monotherapy in the treatment of schizophrenia.

Degree: PhD, Pharmacy (Pharmacy Care Administration), 2003, University of Georgia

URL: http://purl.galileo.usg.edu/uga_etd/ganguly_rahul_200305_phd

► Antipsychotic polypharmacy or concomitant use of multiple antipsychotics is prevalent in up to 40% of schizophrenia patients despite lack of clinical evidence or support from… (more)

▼ Antipsychotic polypharmacy or concomitant use of multiple antipsychotics is prevalent in up to 40% of schizophrenia patients despite lack of clinical evidence or support from treatment guidelines. The objective of this study was to estimate the prevalence and trends of antipsychotic polypharmacy, identify patient factors associated with its use and determine its effect on health care cost and community tenure. Medicaid recipients >=16 years of age with at least one primary diagnosis of schizophrenia (ICD-9-CM=295.**) between 1998-2000 were identified from the Georgia and California (20% random sample) Medicaid claims databases. Antipsychotic polypharmacy cohorts were built in a hierarchical fashion based on antipsychotic use profile i.e. any antipsychotic polypharmacy, clozapine (clozapine + atypical; clozapine + conventional), non-clozapine (atypical+atypical; conventional+conventional; and atypical+conventional) and long-term i.e. duration of use > 2 months and compared with monotherapy controls. 3-year prevalence rates, year wise trends, per capita net oneyear expenditure and one-year hazard rates for hospitalization were reported after adjusting for selection bias. Out of a total of 31,435 persons with schizophrenia, the overall prevalence of antipsychotic polypharmacy was 40% (n=12,549, mean age: 43 years, white: 47%, female: 48%) over 1998-2000 and prevalence of atypical polypharmacy had increased between 1998 and 2000. Long-term antipsychotic polypharmacy had a prevalence rate of 23% (n=7,222) with a long-term episode lasting a median of 197 days. The one-year per capita expenditure for the long-term antipsychotic polypharmacy group was 13,891 which was significantly higher (3,829 95% Confidence Interval [CI], 3,347 to 4,310) than the monotherapy group (10,062) and remained higher even after adjustment for selection bias (1,699 95% CI 760 to 2,638). Polypharmacy was associated with a higher one-year (1.25, 95% CI 1.09 TO 1.41) and two-year (1.45, 95% CI 1.27 to 1.63) hospitalization risk. We did not find any evidence of economic and hospitalization risk related benefit with antipsychotic polypharmacy except a significant net cost in the clozapine+conventional vs clozapine sensitivity analysis (p < 0.0001). Our findings raise concerns regarding the value of antipsychotic polypharmacy and emphasize the need to critically evaluate such treatment decisions in schizophrenia patients. Advisors/Committee Members: Bradley C. Martin.

Subjects/Keywords: Schizophrenia

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APA (6^th Edition):

Ganguly, R. (2003). Antipsychotic polypharmacy vs. monotherapy in the treatment of schizophrenia. (Doctoral Dissertation). University of Georgia. Retrieved from http://purl.galileo.usg.edu/uga_etd/ganguly_rahul_200305_phd

Chicago Manual of Style (16^th Edition):

Ganguly, Rahul. “Antipsychotic polypharmacy vs. monotherapy in the treatment of schizophrenia.” 2003. Doctoral Dissertation, University of Georgia. Accessed February 25, 2020. http://purl.galileo.usg.edu/uga_etd/ganguly_rahul_200305_phd.

MLA Handbook (7^th Edition):

Ganguly, Rahul. “Antipsychotic polypharmacy vs. monotherapy in the treatment of schizophrenia.” 2003. Web. 25 Feb 2020.

Vancouver:

Ganguly R. Antipsychotic polypharmacy vs. monotherapy in the treatment of schizophrenia. [Internet] [Doctoral dissertation]. University of Georgia; 2003. [cited 2020 Feb 25]. Available from: http://purl.galileo.usg.edu/uga_etd/ganguly_rahul_200305_phd.

Council of Science Editors:

Ganguly R. Antipsychotic polypharmacy vs. monotherapy in the treatment of schizophrenia. [Doctoral Dissertation]. University of Georgia; 2003. Available from: http://purl.galileo.usg.edu/uga_etd/ganguly_rahul_200305_phd

University of Georgia

21. Bedwell, Jeffrey Scott. Functional magnetic resonance imaging of the magnocellular visual pathway in nonpsychotic relatives of persons with schizophrenia.

Degree: PhD, Psychology, 2004, University of Georgia

URL: http://purl.galileo.usg.edu/uga_etd/bedwell_jeffrey_s_200405_phd

► Physiological research with monkeys and psychophysical research with humans has demonstrated the ability of diffuse red light to suppress activity in the magnocellular (M) visual… (more)

▼ Physiological research with monkeys and psychophysical research with humans has demonstrated the ability of diffuse red light to suppress activity in the magnocellular (M) visual pathway. In contrast, a previous psychophysical study found that a subset of nonpsychotic relatives of persons with schizophrenia showed the opposite effect, suggesting a novel biobehavioral marker for the disorder. Other research suggests that persons with schizophrenia have a dysfunctional M pathway under neutral (non-red) light conditions. However, it does not appear that these findings have been explored with physiological methods in nonpsychotic relatives, which would provide support for genetic contributions. The current study used physiological methodology to explore whether, as a group: 1) healthy adults show suppression of the M pathway in response to diffuse red light; 2) nonpsychotic relatives of persons with schizophrenia have a dysfunctional M pathway under neutral light conditions; and 3) nonpsychotic relatives of persons with schizophrenia have a differential M pathway response to red light. Functional magnetic resonance imaging (fMRI) was used to investigate a group of 13 nonpsychotic relatives of persons with schizophrenia and 11 controls. Moving concentric rings were presented on both red and green backgrounds to stimulate the M pathway. The fMRI signal strength in bilateral cortical region V5 (MT) was measured as a marker of M pathway functioning. Statistically significant results were limited to measures of fMRI signal in right hemisphere V5 relative to signal from bilateral V5, and suggested that: 1) the control group had reduced M pathway activity in response to diffuse red light; 2) the relative group had a hypoactive M pathway; and 3) a subset of the relatives had the opposite M pathway response to diffuse red light. The differential M pathway response to red light in the relatives remained a statistical trend after controlling for M pathway signal from the neutral (green) background condition. Results provide preliminary evidence that genetic risk for schizophrenia is related to a hypoactive M pathway and an independent differential response (increase in activity) of the M pathway to red light. These features may be more evident in the right hemisphere when examining cortical region V5. Advisors/Committee Members: L. Stephen Miller.

Subjects/Keywords: schizophrenia

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APA (6^th Edition):

Bedwell, J. S. (2004). Functional magnetic resonance imaging of the magnocellular visual pathway in nonpsychotic relatives of persons with schizophrenia. (Doctoral Dissertation). University of Georgia. Retrieved from http://purl.galileo.usg.edu/uga_etd/bedwell_jeffrey_s_200405_phd

Chicago Manual of Style (16^th Edition):

Bedwell, Jeffrey Scott. “Functional magnetic resonance imaging of the magnocellular visual pathway in nonpsychotic relatives of persons with schizophrenia.” 2004. Doctoral Dissertation, University of Georgia. Accessed February 25, 2020. http://purl.galileo.usg.edu/uga_etd/bedwell_jeffrey_s_200405_phd.

MLA Handbook (7^th Edition):

Bedwell, Jeffrey Scott. “Functional magnetic resonance imaging of the magnocellular visual pathway in nonpsychotic relatives of persons with schizophrenia.” 2004. Web. 25 Feb 2020.

Vancouver:

Bedwell JS. Functional magnetic resonance imaging of the magnocellular visual pathway in nonpsychotic relatives of persons with schizophrenia. [Internet] [Doctoral dissertation]. University of Georgia; 2004. [cited 2020 Feb 25]. Available from: http://purl.galileo.usg.edu/uga_etd/bedwell_jeffrey_s_200405_phd.

Council of Science Editors:

Bedwell JS. Functional magnetic resonance imaging of the magnocellular visual pathway in nonpsychotic relatives of persons with schizophrenia. [Doctoral Dissertation]. University of Georgia; 2004. Available from: http://purl.galileo.usg.edu/uga_etd/bedwell_jeffrey_s_200405_phd

University of Georgia

22. Naci, Lorina. Software to measure rambling, cognitive difficulty and degree expression in schizophrenic speech.

Degree: MS, Artificial Intelligence, 2004, University of Georgia

URL: http://purl.galileo.usg.edu/uga_etd/naci_lorina_200412_ms

► This thesis develops new software to help distinguish schizophrenic speech from healthy speech. I used the Natural Language Analysis Tools (Covington 2002) and developed the… (more)

Subjects/Keywords: Schizophrenia

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APA (6^th Edition):

Naci, L. (2004). Software to measure rambling, cognitive difficulty and degree expression in schizophrenic speech. (Masters Thesis). University of Georgia. Retrieved from http://purl.galileo.usg.edu/uga_etd/naci_lorina_200412_ms

Chicago Manual of Style (16^th Edition):

Naci, Lorina. “Software to measure rambling, cognitive difficulty and degree expression in schizophrenic speech.” 2004. Masters Thesis, University of Georgia. Accessed February 25, 2020. http://purl.galileo.usg.edu/uga_etd/naci_lorina_200412_ms.

MLA Handbook (7^th Edition):

Naci, Lorina. “Software to measure rambling, cognitive difficulty and degree expression in schizophrenic speech.” 2004. Web. 25 Feb 2020.

Vancouver:

Naci L. Software to measure rambling, cognitive difficulty and degree expression in schizophrenic speech. [Internet] [Masters thesis]. University of Georgia; 2004. [cited 2020 Feb 25]. Available from: http://purl.galileo.usg.edu/uga_etd/naci_lorina_200412_ms.

Council of Science Editors:

Naci L. Software to measure rambling, cognitive difficulty and degree expression in schizophrenic speech. [Masters Thesis]. University of Georgia; 2004. Available from: http://purl.galileo.usg.edu/uga_etd/naci_lorina_200412_ms

University of Georgia

23. Gutherie, Audrey Hix. The noisy input hypothesis of schizophrenia.

Degree: PhD, Psychology, 2005, University of Georgia

URL: http://purl.galileo.usg.edu/uga_etd/gutherie_audrey_h_200508_phd

► Introduction: Differences in the level of scotopic intrinsic noise were examined in a group of 15 schizophrenia participants and 15 matched controls in order to… (more)

▼ Introduction: Differences in the level of scotopic intrinsic noise were examined in a group of 15 schizophrenia participants and 15 matched controls in order to test the Noisy Input Hypothesis of Schizophrenia, which states that many of the higher-order disturbances that characterize the disorder may be partly due to increased intrinsic noise at the level of sensory input. In addition to intrinsic noise, a number of other variables were measured including scotopic sensitivity (SS), macular pigment optical density (MPOD), critical flicker fusion frequency (CFF), and lens optical density (OD). With the exception of CFF, none of these variables have been assessed in schizophrenia but, based on past evidence, might be expected to differ for this group. Method: Intrinsic noise was assessed by measuring variability in scotopic thresholds. Thresholds were measured using the method of constant stimuli and a two-alternative forced choice procedure. The stimuli consisted of three 1.85-degree diameter test stimuli (at 410, 510, and 565 nm) presented at 10-degrees in the periphery. Lens OD was derived by subtracting the 410 nm log relative scotopic sensitivity (LRSS) values from the 565 nm values. MPOD was measured with a 1-deg test stimulus using heterochromatic flicker photometry. CFF values were obtained with a 1-deg, 570 nm stimulus using the method of limits. Results: The schizophrenia participants did not differ from the control participants with respect to intrinsic noise, LRSS, or lens OD. In contrast, average CFF thresholds (p < 0.004) were significantly lower in the schizophrenia group. The MP density of the schizophrenia participants was 24% lower than the controls and marginally significant (p < 0.08). There were no significant associations between the dependent variables except for MPOD and LRSS. Discussion: The main result of this study, similar intrinsic noise levels in schizophrenia and control participants, does not support the Noisy Input Hypothesis. In fact, the schizophrenia participants were most similar on those items which might be expected to be most linked to the hypothesis (lens OD, LRSS, and intrinsic noise). The largest difference between the groups was in CFF, which is widely considered to be determined by processing at the level of the visual cortex. One interpretation of these results is that many of the visual disturbances reported in schizophrenia are mediated by post-receptoral mechanisms. More data (e.g., larger samples using non-medicated schizophrenia participants), particularly photopic, however, are needed to confirm this interpretation. Advisors/Committee Members: Billy R. Hammond, Jr..

Subjects/Keywords: Schizophrenia

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APA (6^th Edition):

Gutherie, A. H. (2005). The noisy input hypothesis of schizophrenia. (Doctoral Dissertation). University of Georgia. Retrieved from http://purl.galileo.usg.edu/uga_etd/gutherie_audrey_h_200508_phd

Chicago Manual of Style (16^th Edition):

Gutherie, Audrey Hix. “The noisy input hypothesis of schizophrenia.” 2005. Doctoral Dissertation, University of Georgia. Accessed February 25, 2020. http://purl.galileo.usg.edu/uga_etd/gutherie_audrey_h_200508_phd.

MLA Handbook (7^th Edition):

Gutherie, Audrey Hix. “The noisy input hypothesis of schizophrenia.” 2005. Web. 25 Feb 2020.

Vancouver:

Gutherie AH. The noisy input hypothesis of schizophrenia. [Internet] [Doctoral dissertation]. University of Georgia; 2005. [cited 2020 Feb 25]. Available from: http://purl.galileo.usg.edu/uga_etd/gutherie_audrey_h_200508_phd.

Council of Science Editors:

Gutherie AH. The noisy input hypothesis of schizophrenia. [Doctoral Dissertation]. University of Georgia; 2005. Available from: http://purl.galileo.usg.edu/uga_etd/gutherie_audrey_h_200508_phd

University of Georgia

24. Sampson, Salena Ann. Computerized analysis of salient items and discourse organization in schizophrenic picture descriptions.

Degree: MA, English, 2005, University of Georgia

URL: http://purl.galileo.usg.edu/uga_etd/sampson_salena_a_200508_ma

► Computer analysis of spoken picture descriptions shows that schizophrenic patients produce descriptions which are less complete and more disorganized than those produced by healthy controls.… (more)

Subjects/Keywords: Schizophrenia

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APA (6^th Edition):

Sampson, S. A. (2005). Computerized analysis of salient items and discourse organization in schizophrenic picture descriptions. (Masters Thesis). University of Georgia. Retrieved from http://purl.galileo.usg.edu/uga_etd/sampson_salena_a_200508_ma

Chicago Manual of Style (16^th Edition):

Sampson, Salena Ann. “Computerized analysis of salient items and discourse organization in schizophrenic picture descriptions.” 2005. Masters Thesis, University of Georgia. Accessed February 25, 2020. http://purl.galileo.usg.edu/uga_etd/sampson_salena_a_200508_ma.

MLA Handbook (7^th Edition):

Sampson, Salena Ann. “Computerized analysis of salient items and discourse organization in schizophrenic picture descriptions.” 2005. Web. 25 Feb 2020.

Vancouver:

Sampson SA. Computerized analysis of salient items and discourse organization in schizophrenic picture descriptions. [Internet] [Masters thesis]. University of Georgia; 2005. [cited 2020 Feb 25]. Available from: http://purl.galileo.usg.edu/uga_etd/sampson_salena_a_200508_ma.

Council of Science Editors:

Sampson SA. Computerized analysis of salient items and discourse organization in schizophrenic picture descriptions. [Masters Thesis]. University of Georgia; 2005. Available from: http://purl.galileo.usg.edu/uga_etd/sampson_salena_a_200508_ma

University of Georgia

25. He, Congzhou. Using text analysis software in schizophrenia research.

Degree: PhD, Computer Science, 2006, University of Georgia

URL: http://purl.galileo.usg.edu/uga_etd/he_congzhou_200608_phd

► Analysis of speech samples is crucial for schizophrenia research, since language is the outer representation of inner thoughts, and speech abnormality effectively reflects brain deterioration.… (more)

Subjects/Keywords: schizophrenia

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APA (6^th Edition):

He, C. (2006). Using text analysis software in schizophrenia research. (Doctoral Dissertation). University of Georgia. Retrieved from http://purl.galileo.usg.edu/uga_etd/he_congzhou_200608_phd

Chicago Manual of Style (16^th Edition):

He, Congzhou. “Using text analysis software in schizophrenia research.” 2006. Doctoral Dissertation, University of Georgia. Accessed February 25, 2020. http://purl.galileo.usg.edu/uga_etd/he_congzhou_200608_phd.

MLA Handbook (7^th Edition):

He, Congzhou. “Using text analysis software in schizophrenia research.” 2006. Web. 25 Feb 2020.

Vancouver:

He C. Using text analysis software in schizophrenia research. [Internet] [Doctoral dissertation]. University of Georgia; 2006. [cited 2020 Feb 25]. Available from: http://purl.galileo.usg.edu/uga_etd/he_congzhou_200608_phd.

Council of Science Editors:

He C. Using text analysis software in schizophrenia research. [Doctoral Dissertation]. University of Georgia; 2006. Available from: http://purl.galileo.usg.edu/uga_etd/he_congzhou_200608_phd

Rhodes University

26. Stopforth, Penny. An exploration of the other and the disruption of self in schizophrenia.

Degree: Faculty of Humanities, Psychology, 2014, Rhodes University

URL: http://hdl.handle.net/10962/d1016362

► Hermans’ (2002) Dialogical model of Self advocates for a construction of Self that is fluid, diverse and dialogically constructed. He argues that development of ongoing… (more)

▼ Hermans’ (2002) Dialogical model of Self advocates for a construction of Self that is fluid, diverse and dialogically constructed. He argues that development of ongoing dialogues from within and without the Self constitute the Self. These parts of Self that participate in this internal dialogue are referred to by Hermans (2002) as I-positions. Healthy, dynamic internal dialogue between I-positions is argued to contribute to maintaining a unified sense of Self. The Self is also argued to be socially constructed, in so far as Others outside the Self participate in these internal dialogues and are able to influence and occupy I-positions. Research has shown that people with a diagnosis of Schizophrenia experience a unique form of Self disruption. It has been postulated that this disruption is due to disruptions in this internal dialogue. To date, seminal research has primarily focussed on the internal mechanisms and phenomenological accounts of these disruptions. However, little research has focused on the role that Others outside the Self play in these disruptions. Since the Self is also constructed as a social entity, the aim of this research is to explore in what ways the Other contributes and/or minimises this disruption in people with a diagnosis of Schizophrenia. In order to achieve this, I made use of archival data which was made up of the transcripts from semi-structured interviews previously conducted with people with a diagnosis of Schizophrenia as part of a Self and Schizophrenia study. The interviews were analysed using deductive thematic analysis, and utilised Herman’s theory of the Dialogical Self as the theoretical lens for this study. The emergent themes were organised according to those that were present before a diagnosis of Schizophrenia was given and those themes that were present post-diagnosis. The themes reflected that the Other plays a significant role in the both the maintenance of healthy dialogue post diagnosis and well as in the disruption of dialogue. This disruption was primarily observed throughthecompromising of previous I-positions and in the development of new performative and deficit I-positions that contributed to the disruption in internal dialogue.

Subjects/Keywords: Self; Schizophrenia

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APA (6^th Edition):

Stopforth, P. (2014). An exploration of the other and the disruption of self in schizophrenia. (Thesis). Rhodes University. Retrieved from http://hdl.handle.net/10962/d1016362

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Stopforth, Penny. “An exploration of the other and the disruption of self in schizophrenia.” 2014. Thesis, Rhodes University. Accessed February 25, 2020. http://hdl.handle.net/10962/d1016362.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Stopforth, Penny. “An exploration of the other and the disruption of self in schizophrenia.” 2014. Web. 25 Feb 2020.

Vancouver:

Stopforth P. An exploration of the other and the disruption of self in schizophrenia. [Internet] [Thesis]. Rhodes University; 2014. [cited 2020 Feb 25]. Available from: http://hdl.handle.net/10962/d1016362.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Stopforth P. An exploration of the other and the disruption of self in schizophrenia. [Thesis]. Rhodes University; 2014. Available from: http://hdl.handle.net/10962/d1016362

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Hawaii – Manoa

27. Weaver, Daniel Joseph. Political phenomena of schizophrenia from Emil Kraepelin to R.D. Laing.

Degree: PhD, 2009, University of Hawaii – Manoa

URL: http://hdl.handle.net/10125/10092

Typescript.

Bibliography: leaves 376-388.

Microfiche.

vi, 388 leaves

Subjects/Keywords: Schizophrenia

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APA (6^th Edition):

Weaver, D. J. (2009). Political phenomena of schizophrenia from Emil Kraepelin to R.D. Laing. (Doctoral Dissertation). University of Hawaii – Manoa. Retrieved from http://hdl.handle.net/10125/10092

Chicago Manual of Style (16^th Edition):

Weaver, Daniel Joseph. “Political phenomena of schizophrenia from Emil Kraepelin to R.D. Laing.” 2009. Doctoral Dissertation, University of Hawaii – Manoa. Accessed February 25, 2020. http://hdl.handle.net/10125/10092.

MLA Handbook (7^th Edition):

Weaver, Daniel Joseph. “Political phenomena of schizophrenia from Emil Kraepelin to R.D. Laing.” 2009. Web. 25 Feb 2020.

Vancouver:

Weaver DJ. Political phenomena of schizophrenia from Emil Kraepelin to R.D. Laing. [Internet] [Doctoral dissertation]. University of Hawaii – Manoa; 2009. [cited 2020 Feb 25]. Available from: http://hdl.handle.net/10125/10092.

Council of Science Editors:

Weaver DJ. Political phenomena of schizophrenia from Emil Kraepelin to R.D. Laing. [Doctoral Dissertation]. University of Hawaii – Manoa; 2009. Available from: http://hdl.handle.net/10125/10092

University of Hong Kong

28. Tao, Man-wai, Angelina. Clinical and cognitive correlate of gaze pattern in early psychosis.

Degree: Master of Psychological Medicine, 2013, University of Hong Kong

URL: Tao, M. A. [堵敏慧]. (2013). Clinical and cognitive correlate of gaze pattern in early psychosis. (Thesis). University of Hong Kong, Pokfulam, Hong Kong SAR. Retrieved from http://dx.doi.org/10.5353/th_b5088186 ; http://dx.doi.org/10.5353/th_b5088186 ; http://hdl.handle.net/10722/192974

►

Lack of eye contact is one of the key clinical observations in schizophrenia. Sixteen schizophrenic patients and sixteen control subjects participated in our study of… (more)

Subjects/Keywords: Schizophrenia; Psychoses

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APA (6^th Edition):

Tao, Man-wai, A. (2013). Clinical and cognitive correlate of gaze pattern in early psychosis. (Masters Thesis). University of Hong Kong. Retrieved from Tao, M. A. [堵敏慧]. (2013). Clinical and cognitive correlate of gaze pattern in early psychosis. (Thesis). University of Hong Kong, Pokfulam, Hong Kong SAR. Retrieved from http://dx.doi.org/10.5353/th_b5088186 ; http://dx.doi.org/10.5353/th_b5088186 ; http://hdl.handle.net/10722/192974

Chicago Manual of Style (16^th Edition):

Tao, Man-wai, Angelina. “Clinical and cognitive correlate of gaze pattern in early psychosis.” 2013. Masters Thesis, University of Hong Kong. Accessed February 25, 2020. Tao, M. A. [堵敏慧]. (2013). Clinical and cognitive correlate of gaze pattern in early psychosis. (Thesis). University of Hong Kong, Pokfulam, Hong Kong SAR. Retrieved from http://dx.doi.org/10.5353/th_b5088186 ; http://dx.doi.org/10.5353/th_b5088186 ; http://hdl.handle.net/10722/192974.

MLA Handbook (7^th Edition):

Tao, Man-wai, Angelina. “Clinical and cognitive correlate of gaze pattern in early psychosis.” 2013. Web. 25 Feb 2020.

Vancouver:

Tao, Man-wai A. Clinical and cognitive correlate of gaze pattern in early psychosis. [Internet] [Masters thesis]. University of Hong Kong; 2013. [cited 2020 Feb 25]. Available from: Tao, M. A. [堵敏慧]. (2013). Clinical and cognitive correlate of gaze pattern in early psychosis. (Thesis). University of Hong Kong, Pokfulam, Hong Kong SAR. Retrieved from http://dx.doi.org/10.5353/th_b5088186 ; http://dx.doi.org/10.5353/th_b5088186 ; http://hdl.handle.net/10722/192974.

Council of Science Editors:

Tao, Man-wai A. Clinical and cognitive correlate of gaze pattern in early psychosis. [Masters Thesis]. University of Hong Kong; 2013. Available from: Tao, M. A. [堵敏慧]. (2013). Clinical and cognitive correlate of gaze pattern in early psychosis. (Thesis). University of Hong Kong, Pokfulam, Hong Kong SAR. Retrieved from http://dx.doi.org/10.5353/th_b5088186 ; http://dx.doi.org/10.5353/th_b5088186 ; http://hdl.handle.net/10722/192974

29. Kumar, Pawan. Life events and schizophrenia; -.

Degree: Psychology, 1990, Maharshi Dayanand University

URL: http://shodhganga.inflibnet.ac.in/handle/10603/43778

Abstract not available

Bibliography p.90-99, Appendix p.100-136

Advisors/Committee Members: Ravinder and Vohra, A K.

Subjects/Keywords: Schizophrenia

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APA (6^th Edition):

Kumar, P. (1990). Life events and schizophrenia; -. (Thesis). Maharshi Dayanand University. Retrieved from http://shodhganga.inflibnet.ac.in/handle/10603/43778

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Kumar, Pawan. “Life events and schizophrenia; -.” 1990. Thesis, Maharshi Dayanand University. Accessed February 25, 2020. http://shodhganga.inflibnet.ac.in/handle/10603/43778.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Kumar, Pawan. “Life events and schizophrenia; -.” 1990. Web. 25 Feb 2020.

Vancouver:

Kumar P. Life events and schizophrenia; -. [Internet] [Thesis]. Maharshi Dayanand University; 1990. [cited 2020 Feb 25]. Available from: http://shodhganga.inflibnet.ac.in/handle/10603/43778.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Kumar P. Life events and schizophrenia; -. [Thesis]. Maharshi Dayanand University; 1990. Available from: http://shodhganga.inflibnet.ac.in/handle/10603/43778

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

30. Hamm, Jordan Paul. Understanding psychotic pathophysiology with transient, sustained, and oscillatory auditory neural response abnormalities.

Degree: PhD, Neuroscience, 2013, University of Georgia

URL: http://purl.galileo.usg.edu/uga_etd/hamm_jordan_p_201312_phd

► Auditory processing abnormalities are a core feature of psychosis and may underlie perceptual distortions and cognitive deficits characteristic of major psychotic disorders such as schizophrenia… (more)

▼ Auditory processing abnormalities are a core feature of psychosis and may underlie perceptual distortions and cognitive deficits characteristic of major psychotic disorders such as schizophrenia (SZ) and psychotic bipolar disorder (BDP). Attempts at linking experimentally quantified auditory processing abnormalities to underlying biological disease mechanisms and genetic causes have thus far been inconclusive. Such investigations might benefit from i) characterizing abnormalities with respect to underlying psychopathological domains (psychotic, affective) as they cut across DSM-IV diagnostic categories, and ii) appreciating the complexity of the auditory neural response through the use of powerful electrophysiological and analytic tools. Indeed auditory stimulus evoked cortical potentials (measured with scalp electroencephalography) involve spatiotemporally distinct transients (n100 and p200 peaks), sustained slow-potentials, and brief oscillatory events in low (theta), mid (alpha/beta), and high (gamma) frequency bandwidths. Each of these oscillations index unique aspects of local and distributed auditory cortical circuitry. The present set of investigations sought to examine each of these components in the context of interacting psychopathological domains (psychotic versus affective). Measurements were also taken from unaffected family members of persons with SZ or BDP and analysed in the context of both protective and risk factors. The manifold of results indicate that low frequency (delta-theta band) and widely distributed (P300) cortical events show little specificity toward psychotic and affect domains of psychopathology, display general heritability, and are present regardless of context. Early occurring mid-frequency (alpha) and transient events (n100, p200) display psychotic and affective domain specificity, complex heritability patterns (enhanced in non-psychotic first-degree relatives), and are partially ameliorated when auditory stimuli are attended. Finally, high-frequency response abnormalities show the least heritability and are substantially influenced by physical stimulation properties (but not attention). Altogether, this pattern of low versus high frequency and early versus late cortical potentials provides a series of specific hypotheses for future genetic research with regard to neurochemical (gaba/glutamate versus cholinergic/adrenergic) and neuroanatomical (large versus small scale connectivity) pathological processes underlying psychosis and their heterogeneous co-presentations. Advisors/Committee Members: Brett Clementz.

Subjects/Keywords: Schizophrenia

…AUDITORY PAIRED-STIMULI ACROSS THE SCHIZOPHRENIA-BIPOLAR PSYCHOSIS SPECTRUM… …ABNORMALITIES IN SCHIZOPHRENIA ..............119 Introduction… …schizophrenia or bipolar I disorder, they are associated with chronic and significant occupational and… …psychosocial impairment. Schizophrenia (SZ), in particular, is characterized by psychotic… …schizophrenia in particular. The properties of this ERP component show similarities to the “stimulus…

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APA (6^th Edition):

Hamm, J. P. (2013). Understanding psychotic pathophysiology with transient, sustained, and oscillatory auditory neural response abnormalities. (Doctoral Dissertation). University of Georgia. Retrieved from http://purl.galileo.usg.edu/uga_etd/hamm_jordan_p_201312_phd

Chicago Manual of Style (16^th Edition):

Hamm, Jordan Paul. “Understanding psychotic pathophysiology with transient, sustained, and oscillatory auditory neural response abnormalities.” 2013. Doctoral Dissertation, University of Georgia. Accessed February 25, 2020. http://purl.galileo.usg.edu/uga_etd/hamm_jordan_p_201312_phd.

MLA Handbook (7^th Edition):

Hamm, Jordan Paul. “Understanding psychotic pathophysiology with transient, sustained, and oscillatory auditory neural response abnormalities.” 2013. Web. 25 Feb 2020.

Vancouver:

Hamm JP. Understanding psychotic pathophysiology with transient, sustained, and oscillatory auditory neural response abnormalities. [Internet] [Doctoral dissertation]. University of Georgia; 2013. [cited 2020 Feb 25]. Available from: http://purl.galileo.usg.edu/uga_etd/hamm_jordan_p_201312_phd.

Council of Science Editors:

Hamm JP. Understanding psychotic pathophysiology with transient, sustained, and oscillatory auditory neural response abnormalities. [Doctoral Dissertation]. University of Georgia; 2013. Available from: http://purl.galileo.usg.edu/uga_etd/hamm_jordan_p_201312_phd

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