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Freie Universität Berlin

1. Dahlslett, Sarah Bettina. Evaluation of the olfactory and gustatory function in multiple sclerosis patients.

Degree: 2012, Freie Universität Berlin

Propose: to examine the olfactory and gustatory function in patients with multiple sclerosis with subjective and objective testing. The correlation between a higher number and volume of MS lesions in the olfactory brain with a decreased olfactory bulb and olfactory brain volume could help to explain olfactory and gustatory dysfunction in MS patients. 30 Patients und 30 matched, healthy controls were examined for this study: Chemosensory evoked olfactory Potentials: n=21, ortohnasal olfactory function (TDI-score): n=30, retronasal olfactory functiton (Taste powder score): n=23, Taste-function (Taste strip score): n=23 und MRI Caput inkl. Bulbus olfactorius: n=30. 40% of the MS patients showed a loss of olfactory function measured with TDI-score and 23.8% of MS-patients showed hyposmia with OERPs. The gustatory function was limited in 21,7% of the MS-patients. This study also showed that the more the patients suffered from their disease, the poorer their orthonasal olfactory function. The longer and more the patients suffer from their disease, the poorer the orthonasal identification ability was. This study confirms the incidence of olfactory disorder in MS-patients and reveals a frequent gustatory deficit. The identification subtest can be proposed as a marker of the olfactory function in MS-patients: it includes complex cognitive tasks and may be influenced by depression and fatigue, which are common symptoms of MS. It inversely correlates with the disability-status. Advisors/Committee Members: w (gender), Priv.-Doz. Dr. med. Ö. Göktas (firstReferee), Prof. Dr. med. H. Behrbohm (furtherReferee), Priv.-Doz. Dr. med. B. Sedlmaier (furtherReferee).

Subjects/Keywords: multiple sclerosis; objective olfactometry; Sniffin´Sticks; retronasal olfactory testing; taste strips; hyposmia; 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Dahlslett, S. B. (2012). Evaluation of the olfactory and gustatory function in multiple sclerosis patients. (Thesis). Freie Universität Berlin. Retrieved from http://dx.doi.org/10.17169/refubium-14253

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Dahlslett, Sarah Bettina. “Evaluation of the olfactory and gustatory function in multiple sclerosis patients.” 2012. Thesis, Freie Universität Berlin. Accessed February 19, 2020. http://dx.doi.org/10.17169/refubium-14253.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Dahlslett, Sarah Bettina. “Evaluation of the olfactory and gustatory function in multiple sclerosis patients.” 2012. Web. 19 Feb 2020.

Vancouver:

Dahlslett SB. Evaluation of the olfactory and gustatory function in multiple sclerosis patients. [Internet] [Thesis]. Freie Universität Berlin; 2012. [cited 2020 Feb 19]. Available from: http://dx.doi.org/10.17169/refubium-14253.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Dahlslett SB. Evaluation of the olfactory and gustatory function in multiple sclerosis patients. [Thesis]. Freie Universität Berlin; 2012. Available from: http://dx.doi.org/10.17169/refubium-14253

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

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