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McMaster University
1.
Kosa, Sarah Daisy.
A Design Thesis: Hemodialysis Infection Prevention using Polysporin Ointment with Shower Technique in Satellite Hemodialysis Centres.
Degree: MSc, 2014, McMaster University
URL: http://hdl.handle.net/11375/16451 
► Background: As part of this thesis work, we developed a Shower Technique protocol (‘STP’) for hemodialysis patients with healed central venous catheter (catheter) exit sites,…
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▼ Background: As part of this thesis work, we developed a Shower Technique protocol (‘STP’) for hemodialysis patients with healed central venous catheter (catheter) exit sites, designed to permit showering but not increase infection risk.
Research question: Is it feasible to conduct a randomized control trial called the Hemodialysis Infection Prevention using Polysporin Ointment with Shower Technique in Satellite Centres (HIPPO SAT) study comparing the rate of CRB in adult satellite hemodialysis patients using STP versus standard catheter care alone with 6 month follow up?
Study Design: The HIPPO SAT pilot study is a multi-centre randomized control trial. Eligible participants will be randomized to STP versus standard care after meeting predefined criteria to confirm healed tunneled catheter exit site.
Primary Outcome: Feasibility will be determined based on 5 outcome measures: accuracy of the CRB rate documentation in the satellite setting, and percentage of patients screened, recruited, educated successfully in the STP (intervention arm), and using aspects of STP (% of contaminated patients in the control arm).
Study Setting: In satellite units affiliated with 2 academic and 3 community centres in south central Ontario, Canada.
Patient Population: Adult satellite Hemodialysis patients dialyzing via catheter with healed catheter exit sites.
Intervention: STP and standard catheter care; or Control: standard catheter care;
Analysis: Each measure of feasibility has its statistical threshold for success. If the threshold is reached in 4 of the 5 measures, the full HIPPO SAT study will be deemed feasible.
Discussion: A pilot feasibility study of the larger study is critical due to the potential challenges associated with recruitment, compliance and contamination.
Thesis
Master of Science (MSc)
Advisors/Committee Members: Lok, Charmaine, Lehana, Thabane, Health Research Methodology.
Subjects/Keywords: hemodialysis; randomized controlled trial
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APA (6th Edition):
Kosa, S. D. (2014). A Design Thesis: Hemodialysis Infection Prevention using Polysporin Ointment with Shower Technique in Satellite Hemodialysis Centres. (Masters Thesis). McMaster University. Retrieved from http://hdl.handle.net/11375/16451
Chicago Manual of Style (16th Edition):
Kosa, Sarah Daisy. “A Design Thesis: Hemodialysis Infection Prevention using Polysporin Ointment with Shower Technique in Satellite Hemodialysis Centres.” 2014. Masters Thesis, McMaster University. Accessed February 24, 2021.
http://hdl.handle.net/11375/16451.
MLA Handbook (7th Edition):
Kosa, Sarah Daisy. “A Design Thesis: Hemodialysis Infection Prevention using Polysporin Ointment with Shower Technique in Satellite Hemodialysis Centres.” 2014. Web. 24 Feb 2021.
Vancouver:
Kosa SD. A Design Thesis: Hemodialysis Infection Prevention using Polysporin Ointment with Shower Technique in Satellite Hemodialysis Centres. [Internet] [Masters thesis]. McMaster University; 2014. [cited 2021 Feb 24].
Available from: http://hdl.handle.net/11375/16451.
Council of Science Editors:
Kosa SD. A Design Thesis: Hemodialysis Infection Prevention using Polysporin Ointment with Shower Technique in Satellite Hemodialysis Centres. [Masters Thesis]. McMaster University; 2014. Available from: http://hdl.handle.net/11375/16451
Queens University
2.
Chin, Jacqueline.
A Suicide Prevention Approach: Expanding One’s Time Perspective
.
Degree: Psychology, 2011, Queens University
URL: http://hdl.handle.net/1974/6684
► The current study examined the efficacy of a 1 month future time perspective modification intervention over a 1 month and 6 months period. Participants (N…
(more)
▼ The current study examined the efficacy of a 1 month future time perspective modification intervention over a 1 month and 6 months period. Participants (N = 92) with elevated scores on measures of depressive symptoms or suicidal ideation were assigned to either the intervention condition or a no-intervention control condition. A repeated-measures manova revealed that those in the time perspective modification intervention condition showed significant reductions in psychache and hopelessness at 1 month, relative to those in the control condition. Repeated-measures manovas did not reveal significantly greater changes in depressive symptoms, suicidal ideation, or future time perspective. No results at 6 months were found to be significant. These results suggest that a future time perspective modification intervention can reduce important predictors of suicidality, although the sustainability of these gains and their relation to suicide is unclear.
Subjects/Keywords: Randomized Control Trial
;
Suicide Prevention
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APA (6th Edition):
Chin, J. (2011). A Suicide Prevention Approach: Expanding One’s Time Perspective
. (Thesis). Queens University. Retrieved from http://hdl.handle.net/1974/6684
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Chin, Jacqueline. “A Suicide Prevention Approach: Expanding One’s Time Perspective
.” 2011. Thesis, Queens University. Accessed February 24, 2021.
http://hdl.handle.net/1974/6684.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Chin, Jacqueline. “A Suicide Prevention Approach: Expanding One’s Time Perspective
.” 2011. Web. 24 Feb 2021.
Vancouver:
Chin J. A Suicide Prevention Approach: Expanding One’s Time Perspective
. [Internet] [Thesis]. Queens University; 2011. [cited 2021 Feb 24].
Available from: http://hdl.handle.net/1974/6684.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Chin J. A Suicide Prevention Approach: Expanding One’s Time Perspective
. [Thesis]. Queens University; 2011. Available from: http://hdl.handle.net/1974/6684
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Louisiana State University
3.
Barbera, Brooke Louise.
Measurement of pain, pain disability, and pain beliefs of morbidly obese adults.
Degree: PhD, Psychology, 2012, Louisiana State University
URL: etd-04142012-062820
;
https://digitalcommons.lsu.edu/gradschool_dissertations/1900
► Both obesity and pain are pervasive public health problems, contributing to significant disability in the United States and worldwide. Studies have demonstrated a positive association…
(more)
▼ Both obesity and pain are pervasive public health problems, contributing to significant disability in the United States and worldwide. Studies have demonstrated a positive association between obesity and pain, with increasing BMI related to increasing levels of pain intensity; however, the mechanisms underlying this relationship are not well understood. The present study assessed the presence of pain, pain-related disability, and pain beliefs in a morbidly obese (BMI > 40 kg/m2) sample participating in a medically-supervised, nonsurgical weight loss intervention. After controlling for demographic variables and depression, pain was reported in 36.7% of the sample (N = 390). Results indicated that greater level of pain severity at the outset of treatment was significantly associated with poorer weight loss treatment outcome at one year [F(3, 205) = 20.50, p < .001]. Pain beliefs, specifically catastrophizing, did not contribute to this relationship. The presence of pain was also significantly related with decrements in health-related quality of life, after controlling for the impact of age, BMI, and depression [F(4, 204) = 14.61, p < .001]. The findings of the present study provide preliminary evidence that pain severity is an important indicator of treatment outcomes for morbidly obese individuals trying to lose weight by nonsurgical methods. Further research is needed to more clearly understand prognostic implications of the comorbidity of pain on obesity treatment, as well as the impact of incremental weight loss on pain outcomes.
Subjects/Keywords: bariatric surgery; multisite trial; LOSS; pragmatic clinical trial; randomized controlled trial
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APA (6th Edition):
Barbera, B. L. (2012). Measurement of pain, pain disability, and pain beliefs of morbidly obese adults. (Doctoral Dissertation). Louisiana State University. Retrieved from etd-04142012-062820 ; https://digitalcommons.lsu.edu/gradschool_dissertations/1900
Chicago Manual of Style (16th Edition):
Barbera, Brooke Louise. “Measurement of pain, pain disability, and pain beliefs of morbidly obese adults.” 2012. Doctoral Dissertation, Louisiana State University. Accessed February 24, 2021.
etd-04142012-062820 ; https://digitalcommons.lsu.edu/gradschool_dissertations/1900.
MLA Handbook (7th Edition):
Barbera, Brooke Louise. “Measurement of pain, pain disability, and pain beliefs of morbidly obese adults.” 2012. Web. 24 Feb 2021.
Vancouver:
Barbera BL. Measurement of pain, pain disability, and pain beliefs of morbidly obese adults. [Internet] [Doctoral dissertation]. Louisiana State University; 2012. [cited 2021 Feb 24].
Available from: etd-04142012-062820 ; https://digitalcommons.lsu.edu/gradschool_dissertations/1900.
Council of Science Editors:
Barbera BL. Measurement of pain, pain disability, and pain beliefs of morbidly obese adults. [Doctoral Dissertation]. Louisiana State University; 2012. Available from: etd-04142012-062820 ; https://digitalcommons.lsu.edu/gradschool_dissertations/1900
University of Alberta
4.
Hartling, Lisa.
A randomized controlled trial of storytelling as a
communication tool aimed at parents of children presenting to the
emergency department with croup.
Degree: PhD, Medical Sciences-Paediatrics, 2010, University of Alberta
URL: https://era.library.ualberta.ca/files/02870x17p
► Background: Stories may be an effective tool to communicate with and influence patients because of their ability to engage the reader. Objectives: To develop story…
(more)
▼ Background: Stories may be an effective tool to
communicate with and influence patients because of their ability to
engage the reader. Objectives: To develop story booklets and
evaluate their effectiveness compared to standard information
sheets for parents of children attending the emergency department
(ED) with a child with croup. Methods: A systematic process was
followed to develop and pilot-test the story booklets. Parents were
randomized to receive story booklets or standard information sheets
during their ED visit. The primary outcome of change in anxiety
during the ED visit was assessed using the State Trait Anxiety
Inventory, which was completed upon recruitment and at discharge.
Follow-up telephone interviews were conducted at 1 and 3 days
post-ED visit to gather information on secondary outcomes:
symptoms, expected anxiety for future croup, satisfaction, regret,
knowledge, return for medical care, and resource use. Telephone
interviews were conducted every other day until symptoms resolved
or until day 9. Outcomes were compared using independent-groups
t-tests, Mann Whitney tests, or Chi-square tests. Results: There
was no significant difference in the primary outcome of change in
parental anxiety between recruitment and ED discharge. The story
group (n=129) showed significantly greater decision regret
regarding their decision to go to the ED than the comparison group
(n=126) (p<0.001). The story group reported quicker
resolution of symptoms: median days to no symptoms 3 versus 5; the
survival distributions were significantly different (p=0.032).
There were no differences for the remaining outcomes. Conclusions:
This study provides preliminary evidence regarding the use of
stories in the ED for an acute, self-limiting condition and
contributes to a growing evidence matrix identifying when, where,
and for whom storytelling may be most effective. Reasons for lack
of significance for the primary and other outcomes may relate to
choice of outcome, timing of outcome assessment, or disconnect
between the intervention and needs of the end-user. Further
research is needed to corroborate the significant findings and
examine their underlying mechanism. An examination of risk of bias
in a sample of pediatric trials demonstrates that there is room for
improvement in the design, conduct, and reporting of research
related to child health and provides direction for future
research.
Subjects/Keywords: storytelling, narrative, randomized controlled trial,
croup, parent
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APA (6th Edition):
Hartling, L. (2010). A randomized controlled trial of storytelling as a
communication tool aimed at parents of children presenting to the
emergency department with croup. (Doctoral Dissertation). University of Alberta. Retrieved from https://era.library.ualberta.ca/files/02870x17p
Chicago Manual of Style (16th Edition):
Hartling, Lisa. “A randomized controlled trial of storytelling as a
communication tool aimed at parents of children presenting to the
emergency department with croup.” 2010. Doctoral Dissertation, University of Alberta. Accessed February 24, 2021.
https://era.library.ualberta.ca/files/02870x17p.
MLA Handbook (7th Edition):
Hartling, Lisa. “A randomized controlled trial of storytelling as a
communication tool aimed at parents of children presenting to the
emergency department with croup.” 2010. Web. 24 Feb 2021.
Vancouver:
Hartling L. A randomized controlled trial of storytelling as a
communication tool aimed at parents of children presenting to the
emergency department with croup. [Internet] [Doctoral dissertation]. University of Alberta; 2010. [cited 2021 Feb 24].
Available from: https://era.library.ualberta.ca/files/02870x17p.
Council of Science Editors:
Hartling L. A randomized controlled trial of storytelling as a
communication tool aimed at parents of children presenting to the
emergency department with croup. [Doctoral Dissertation]. University of Alberta; 2010. Available from: https://era.library.ualberta.ca/files/02870x17p
University of Guelph
5.
Hilton, William J.
The Feasibility and Efficacy of Prehabilitation for Prostate Cancer Surgery.
Degree: MS, Department of Human Health and Nutritional Sciences, 2016, University of Guelph
URL: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/10110
► Physical activity and fitness are predictors of post-operative prostate cancer recovery; however the capacity to improve pre-operative fitness in this population has yet to be…
(more)
▼ Physical activity and fitness are predictors of post-operative prostate cancer recovery; however the capacity to improve pre-operative fitness in this population has yet to be demonstrated in a
randomized controlled
trial. This study examined the feasibility and efficacy of conducting a pre-operative total-body exercise program, also known as prehabilitation, for men undergoing radical prostatectomy. Participants were prescribed home-based, moderate-intensity exercise, and/or pelvic floor muscle strengthening exercise. To estimate intervention efficacy, fitness and psychosocial outcomes were measured at baseline and ∼1 week pre-operatively. From February 2014 to September 2015, 113 eligible patients were approached; 50 consented (recruitment rate = 44.2%) and were
randomized to a comprehensive prehabilitation intervention or control group. Participants were mostly Caucasian and had a mean age of 61.1 years. Twelve participants withdrew pre-operatively (attrition rate = 24%). Statistically significant between-group differences were observed in body fat, waist circumference and emotional well-being in favor of the prehabilitation intervention. To our knowledge, this is the first study to assess feasibility and efficacy of a total-body exercise program in the home-based setting prior to radical prostatectomy.
Advisors/Committee Members: Lawrence, Spriet (advisor), Santa Mina, Daniel (advisor).
Subjects/Keywords: Prehabilitation; Prostate cancer; Exercise; Randomized controlled trial
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APA (6th Edition):
Hilton, W. J. (2016). The Feasibility and Efficacy of Prehabilitation for Prostate Cancer Surgery. (Masters Thesis). University of Guelph. Retrieved from https://atrium.lib.uoguelph.ca/xmlui/handle/10214/10110
Chicago Manual of Style (16th Edition):
Hilton, William J. “The Feasibility and Efficacy of Prehabilitation for Prostate Cancer Surgery.” 2016. Masters Thesis, University of Guelph. Accessed February 24, 2021.
https://atrium.lib.uoguelph.ca/xmlui/handle/10214/10110.
MLA Handbook (7th Edition):
Hilton, William J. “The Feasibility and Efficacy of Prehabilitation for Prostate Cancer Surgery.” 2016. Web. 24 Feb 2021.
Vancouver:
Hilton WJ. The Feasibility and Efficacy of Prehabilitation for Prostate Cancer Surgery. [Internet] [Masters thesis]. University of Guelph; 2016. [cited 2021 Feb 24].
Available from: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/10110.
Council of Science Editors:
Hilton WJ. The Feasibility and Efficacy of Prehabilitation for Prostate Cancer Surgery. [Masters Thesis]. University of Guelph; 2016. Available from: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/10110
University of Minnesota
6.
He, Xuehuan.
Modeling Of The Interaction Between Colon And Colonoscope During A Colonoscopy.
Degree: M.S.M.E., Mechanical Engineering, 2018, University of Minnesota
URL: http://hdl.handle.net/11299/198970
► One of the main complications in completing a colonoscopy is that the colonoscope causes patient pain during the procedure. To reduce patient pain, small-caliber (SC)…
(more)
▼ One of the main complications in completing a colonoscopy is that the colonoscope causes patient pain during the procedure. To reduce patient pain, small-caliber (SC) colonoscopes have been developed. To evaluate the efficacy of SC colonoscopes in reducing patient pain with that of traditional standard colonoscope (SDC), several randomized control trials (RCTs) were conducted and showed varying results, with some showed benefits whereas others did not. Among these RCTs, patient characteristics, including gender, age, and region were varied and further assumed to be responsible for the varied results. However, the influence of patient characteristics on the efficacy of SC colonoscopes in terms of reducing patient pain is still unclear due to many unavoidable disturbing factors in RCTs, including endoscopists’ skills, bowel preparation methods, and other new beneficial features of colonoscopes (passive bending and high force transmission shaft). Therefore, to explore the influence of gender, age, and region of patients on the efficacy of SC colonoscopes in terms of reducing patient pain, a numerical model could overcome the limitations of RCTs and provide such insight is developed in our work. As a first step, the structural differences of the human colon with respect to gender, age, and region were analyzed and summarized, which further functions as the basis of the development of colon models and their boundary conditions. As a result, three normalized colon segments were selected and modelled, including rectosigmoid junction (RCJ), rectum-splenic flexure (RSF), and transverse-hepatic flexure (THF) models. The colonoscope was modelled as a thin and flexible cylinder with a hemisphere tip. Three different diameters were applied to colonoscope models, including 9.2mm for ultrathin colonoscope (UTC), 11.3mm for pediatric colonoscope (PDC), and 12.8mm for standard colonoscope (SDC). UTC and PDC were classified as SC colonoscopes. In the stage of insertion simulation, a comparison between implicit and explicit finite element solution method was conducted, and then an explicit solver ANSYS-LSDYNA was selected to simulate the insertion process of colonoscopes in colon models. An uni-axial tension test was carried out to provide the experimental data of a porcine colon, and then an optimization procedure with the use of ANSYS and Optislang programs was performed to provide the necessary parameters of the constitutive material model of the colonic tissue. By comparing colon deformation during the insertion simulation, patient pain induced by colonoscopes were further predicted. The model developed in this research serves as a starting point in understanding the efficacy of SC colonoscopes in reducing patient pain considering the effects of patient characteristics, including gender, age, and region. This model may also provide scientific guidelines for the selection of patient specified colonoscope
Subjects/Keywords: Colonoscope; Patient pain; Randomized controlled trial
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APA (6th Edition):
He, X. (2018). Modeling Of The Interaction Between Colon And Colonoscope During A Colonoscopy. (Masters Thesis). University of Minnesota. Retrieved from http://hdl.handle.net/11299/198970
Chicago Manual of Style (16th Edition):
He, Xuehuan. “Modeling Of The Interaction Between Colon And Colonoscope During A Colonoscopy.” 2018. Masters Thesis, University of Minnesota. Accessed February 24, 2021.
http://hdl.handle.net/11299/198970.
MLA Handbook (7th Edition):
He, Xuehuan. “Modeling Of The Interaction Between Colon And Colonoscope During A Colonoscopy.” 2018. Web. 24 Feb 2021.
Vancouver:
He X. Modeling Of The Interaction Between Colon And Colonoscope During A Colonoscopy. [Internet] [Masters thesis]. University of Minnesota; 2018. [cited 2021 Feb 24].
Available from: http://hdl.handle.net/11299/198970.
Council of Science Editors:
He X. Modeling Of The Interaction Between Colon And Colonoscope During A Colonoscopy. [Masters Thesis]. University of Minnesota; 2018. Available from: http://hdl.handle.net/11299/198970
University of Oregon
7.
Latham, Melissa.
A Micro-Randomized Trial To Improve College Students’ Wake Time Regularity.
Degree: PhD, Department of Psychology, 2020, University of Oregon
URL: https://scholarsbank.uoregon.edu/xmlui/handle/1794/25581
► Many college students experience irregular sleep patterns due to their unique schedule. These patterns confer risk for other sleep problems as well as mental health…
(more)
▼ Many college students experience irregular sleep patterns due to their unique schedule. These patterns confer risk for other sleep problems as well as mental health difficulties including mood disorders, physical aggression, and suicidal ideation. Current interventions to improve college students’ sleep are often created using Cognitive Behavioral Therapy for Insomnia components, although the components used are often not consistent. These interventions are also plagued by drop out, often by those that need the intervention the most.
The current study takes a step toward creating an intervention with fewer, simpler components that is more agreeable to college students due to its ease and delivery through a phone-based application. In order to achieve this, I use a micro-
randomized trial design to assess the most effective timing and content for an intervention that reminds students of techniques to help increase the regularity of their wake up times. The aims of the study were 1) to determine the feasibility and acceptability of the intervention; 2) to determine the effect of the reminders on immediate use of sleep hygiene strategies and on subsequent wake time regularity; and 3) to determine whether proximal outcomes were related to variability in wake times at the end of the intervention. Participants completed a baseline week of sleep diaries, an online psychoeducation module about sleep regularity, and then entered the intervention phase, where they were
randomized each day to receive a reminder. If they were
randomized to receive one, the timing and content of that reminder were also
randomized.
The results of this study indicate that participants were invested in completing our intervention and found it somewhat helpful. However, there was no effect of the reminders nor their timing or content on proximal outcomes. Lastly, there was no relationship between sleep hygiene use and wake time variability during the final week of the study. Although our results indicate that the intervention components were not effective, future iterations of the study are being planned to address several important limitations. The goal of the next iteration will be to assess the effect of these reminders without a number of unintended, confounding factors.
Advisors/Committee Members: Allen, Nicholas (advisor).
Subjects/Keywords: college; intervention; micro-randomized trial; regularity; sleep
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APA ·
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APA (6th Edition):
Latham, M. (2020). A Micro-Randomized Trial To Improve College Students’ Wake Time Regularity. (Doctoral Dissertation). University of Oregon. Retrieved from https://scholarsbank.uoregon.edu/xmlui/handle/1794/25581
Chicago Manual of Style (16th Edition):
Latham, Melissa. “A Micro-Randomized Trial To Improve College Students’ Wake Time Regularity.” 2020. Doctoral Dissertation, University of Oregon. Accessed February 24, 2021.
https://scholarsbank.uoregon.edu/xmlui/handle/1794/25581.
MLA Handbook (7th Edition):
Latham, Melissa. “A Micro-Randomized Trial To Improve College Students’ Wake Time Regularity.” 2020. Web. 24 Feb 2021.
Vancouver:
Latham M. A Micro-Randomized Trial To Improve College Students’ Wake Time Regularity. [Internet] [Doctoral dissertation]. University of Oregon; 2020. [cited 2021 Feb 24].
Available from: https://scholarsbank.uoregon.edu/xmlui/handle/1794/25581.
Council of Science Editors:
Latham M. A Micro-Randomized Trial To Improve College Students’ Wake Time Regularity. [Doctoral Dissertation]. University of Oregon; 2020. Available from: https://scholarsbank.uoregon.edu/xmlui/handle/1794/25581
Georgia State University
8.
Fallon, Elizabeth A.
The Role of Health Literacy and Numeracy on Exercise Self-efficacy and Exercise Behavior in the PAADRN Bone Health Intervention.
Degree: MPH, Public Health, 2015, Georgia State University
URL: https://scholarworks.gsu.edu/iph_theses/426
► INTRODUCTION: Osteoporotic bone fracture is a major cause of hospitalization, disability, loss of independent living capacity, and mortality among aging adults. Although physical exercise…
(more)
▼ INTRODUCTION: Osteoporotic bone fracture is a major cause of hospitalization, disability, loss of independent living capacity, and mortality among aging adults. Although physical exercise may sustain bone mineral density and prevent falls and fractures among individuals at risk for low bone mineral density, adherence to exercise recommendations is low. Increasing efficacy and effectiveness of treatment for osteoporosis would benefit from examination of heterogeneity of treatment effects. Previous research indicates that poor health literacy (HL) and health numeracy (HN) may be associated with less exercise behavior and heterogeneity of treatment effects may be evident across high and low level of health literacy and/or health numeracy.
AIM: Examine heterogeneity of treatment effects due to HL/HN on post-intervention exercise self-efficacy and exercise behavior among older adults enrolled in a large, multi-site
randomized controlled
trial designed to increase exercise as part of osteoporosis guideline concordant care.
METHODS: A secondary data analysis was conducted, utilizing a modified intent-to-treat approach. Linear mixed models with and without covariates were conducted to examine heterogeneity of treatment effects by incorporating the treatment by high/low HL/HN interaction. Analyses were conducted using pooled, as well as site-specific samples.
Advisors/Committee Members: Douglas W. Roblin, Ph.D., Fredric D. Wolinsky, Ph.D..
Subjects/Keywords: motor activity; osteoporosis; randomized controlled trial; pragmatic clinical trial
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APA (6th Edition):
Fallon, E. A. (2015). The Role of Health Literacy and Numeracy on Exercise Self-efficacy and Exercise Behavior in the PAADRN Bone Health Intervention. (Thesis). Georgia State University. Retrieved from https://scholarworks.gsu.edu/iph_theses/426
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Fallon, Elizabeth A. “The Role of Health Literacy and Numeracy on Exercise Self-efficacy and Exercise Behavior in the PAADRN Bone Health Intervention.” 2015. Thesis, Georgia State University. Accessed February 24, 2021.
https://scholarworks.gsu.edu/iph_theses/426.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Fallon, Elizabeth A. “The Role of Health Literacy and Numeracy on Exercise Self-efficacy and Exercise Behavior in the PAADRN Bone Health Intervention.” 2015. Web. 24 Feb 2021.
Vancouver:
Fallon EA. The Role of Health Literacy and Numeracy on Exercise Self-efficacy and Exercise Behavior in the PAADRN Bone Health Intervention. [Internet] [Thesis]. Georgia State University; 2015. [cited 2021 Feb 24].
Available from: https://scholarworks.gsu.edu/iph_theses/426.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Fallon EA. The Role of Health Literacy and Numeracy on Exercise Self-efficacy and Exercise Behavior in the PAADRN Bone Health Intervention. [Thesis]. Georgia State University; 2015. Available from: https://scholarworks.gsu.edu/iph_theses/426
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Universidade do Rio Grande do Sul
9.
Angst, Patrícia Daniela Melchiors.
Efeito do controle supragengival em comparação ao controle combinado supra e subgengival durante a fase de manutenção periódica preventiva : resultados microbiológicos.
Degree: 2015, Universidade do Rio Grande do Sul
URL: http://hdl.handle.net/10183/128798
► Objetivos: Comparar o efeito do controle estrito do biofilme supragengival (SUPRA), em comparação ao controle combinado dos biofilmes supra e subgengival (SUPRA+SUB), na microbiota subgengival…
(more)
▼ Objetivos: Comparar o efeito do controle estrito do biofilme supragengival (SUPRA), em comparação ao controle combinado dos biofilmes supra e subgengival (SUPRA+SUB), na microbiota subgengival de pacientes durante a fase de manutenção periódica preventiva (MPP), ao longo de 1 ano. Materiais e métodos: Sessenta e dois pacientes com periodontite moderada ou avançada (idade média 50.97 ± 9.26 anos, 40 mulheres, 24 fumantes) foram tratados de acordo com um protocolo não-cirúrgico. Finalizada a fase terapêutica, os pacientes iniciaram a fase de MPP e foram randomicamente alocados para receber a intervenção SUPRA ou SUPRA+SUB. Exames periodontais, instruções de higiene bucal, e as respectivas intervenções (SUPRA ou SUPRA+SUB) foram realizados em consultas trimestrais. Biofilme subgengival foi coletado ao baseline, 3, 6 e 12 meses. Técnica de PCR em Tempo Real foi utilizada para quantificar as espécies bacterianas Porphyromonas gingivalis (Pg), Treponema denticola (Td), Tannerella forsythia (Tf), e o domínio Eubacteria (Bactérias totais). Equações de estimação generalizadas foram usadas para se estimar os efeitos dos tratamentos considerando-se a avaliação longitudinal. Resultados: Não foram observadas diferenças significativas entre os grupos para as contagens de Pg, Td, Tf, e Bactérias totais ao longo de 1 ano. Contudo, a partir dos 3 meses, as contagens de Pg e Tf aumentaram significativamente em ambos os grupos. As contagens de Bactérias totais e Td foram mantidas longitudinalmente. Por outro lado, as contagens médias das espécies bacterianas alvo permaneceram em baixos níveis (≤ 103) durante todo o estudo. Paralelamente, os parâmetros clínicos foram mantidos sem alterações significativas. Conclusões: As intervenções de manutenção investigadas produziram resultados microbiológicos semelhantes ao longo do tempo, o que demonstra o grande e importante impacto do controle do biofilme supragengival durante a fase de MPP.
Aim: Compare the effects of supragingival scaling alone (SPG) against the combined supra and subgingival scaling (SPG+SBG), on subgingival microbiota from patients during periodontal maintenance period (PMP), along 1 year. Material and Methods: Sixty-two patients with moderate or severe periodontitis (mean age 50.97 ± 9.26, 40 females, 24 smokers) were treated according to a non-surgical protocol. Ended the therapy phase, they entered a PMP and were randomly allocated to receive SPG or SPG+SBG interventions. Periodontal exams, oral hygiene instructions, and the respective intervention (SPG or SPG+SBG) were performed at quarterly appointments. Subgingival biofilm was sampled at baseline, 3, 6 and 12 months. Real-time PCR technique was used to quantify the bacteria species Porphyromonas gingivalis (Pg), Treponema denticola (Td), Tannerella forsythia (Tf), and Eubacteria domain (Total bacteria). Generalized estimating equations were used to estimate treatment effects while accounting for longitudinal evaluation. Results: No significant inter-groups differences were observed to Pg, Td, Tf, and Total bacteria…
Advisors/Committee Members: Gomes, Sabrina Carvalho.
Subjects/Keywords: Periodontite; Long-term care; Microbiology; Microbiologia; Biofilmes; Periodontitis; Randomized controlled trial
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APA (6th Edition):
Angst, P. D. M. (2015). Efeito do controle supragengival em comparação ao controle combinado supra e subgengival durante a fase de manutenção periódica preventiva : resultados microbiológicos. (Thesis). Universidade do Rio Grande do Sul. Retrieved from http://hdl.handle.net/10183/128798
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Angst, Patrícia Daniela Melchiors. “Efeito do controle supragengival em comparação ao controle combinado supra e subgengival durante a fase de manutenção periódica preventiva : resultados microbiológicos.” 2015. Thesis, Universidade do Rio Grande do Sul. Accessed February 24, 2021.
http://hdl.handle.net/10183/128798.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Angst, Patrícia Daniela Melchiors. “Efeito do controle supragengival em comparação ao controle combinado supra e subgengival durante a fase de manutenção periódica preventiva : resultados microbiológicos.” 2015. Web. 24 Feb 2021.
Vancouver:
Angst PDM. Efeito do controle supragengival em comparação ao controle combinado supra e subgengival durante a fase de manutenção periódica preventiva : resultados microbiológicos. [Internet] [Thesis]. Universidade do Rio Grande do Sul; 2015. [cited 2021 Feb 24].
Available from: http://hdl.handle.net/10183/128798.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Angst PDM. Efeito do controle supragengival em comparação ao controle combinado supra e subgengival durante a fase de manutenção periódica preventiva : resultados microbiológicos. [Thesis]. Universidade do Rio Grande do Sul; 2015. Available from: http://hdl.handle.net/10183/128798
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
University of California – Berkeley
10.
Polimeni, Rachel.
Health Insurance in Rural Cambodia: Impacts and Selection.
Degree: Economics, 2011, University of California – Berkeley
URL: http://www.escholarship.org/uc/item/5jh52309
► High health care expenditures following a health shock can lead to long-term economic consequences. Health insurance has the potential to avert economic difficulties following health…
(more)
▼ High health care expenditures following a health shock can lead to long-term economic consequences. Health insurance has the potential to avert economic difficulties following health shocks, increase health care utilization and improve health. However, adverse selection in health insurance markets may stop voluntary health insurance markets from providing protection to most consumers without substantial regulation and subsidization. If uninsured individuals forgo valuable health care due to lack of funds, health insurance can also increase health care utilization and improve health. These potential benefits of insurance have led many developing nations to consider health insurance as a policy tool. Yet, even in developed nations, there have been few studies to measure its effectiveness. This dissertation consists of three chapters that evaluate the SKY Micro-health insurance program in rural Cambodia. In Chapter 1 I evaluate the health and economic effects of the SKY insurance program on rural households using a randomized controlled trial. By randomizing the insurance premium we induce random variation in the likelihood of insurance take-up that allows us to estimate the causal effects of health insurance on economic outcomes, health utilization, and health outcomes.We find that SKY insurance has the greatest impact on economic outcomes, as expected from an insurance program. For example, SKY decreased total health-care costs of serious health shocks by over 40%, and households with SKY had over one-third less debt and over 75% less health-related debt. SKY also changed health-seeking behavior, increasing use of (covered) public facilities and decreasing use of (uncovered) unregulated care. At the same time, SKY had no detectable impact on preventative care. As expected due to low statistical power, we did not find statistically significant impacts on health. In Chapter 2 I study adverse selection into this insurance market. As part of this study I use the randomized experimental design to separate adverse selection from moral hazard. I test three implications of theories of adverse selection: that households joining are more adversely selected based on characteristics observable at the baseline; that households that purchase insurance at a high price are more adversely selected on observables than those that purchase identical coverage at a lower price; and that households that purchase at the higher price will demonstrate more adverse selection in utilization than households purchasing coverage at a lower price even after holding constant baseline characteristics ("unobservable" selection). I find that households that purchase insurance have some characteristics consistent with higher expected health care utilization. Contrary to expectations, households paying a higher price do not demonstrate more selection on characteristics observable prior to insurance purchase. However, households that paid more for health insurance have substantially higher usage of both health centers and hospitals than…
Subjects/Keywords: Economics; Cambodia; health; impact evaluation; insurance; randomized trial; selection
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APA (6th Edition):
Polimeni, R. (2011). Health Insurance in Rural Cambodia: Impacts and Selection. (Thesis). University of California – Berkeley. Retrieved from http://www.escholarship.org/uc/item/5jh52309
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Polimeni, Rachel. “Health Insurance in Rural Cambodia: Impacts and Selection.” 2011. Thesis, University of California – Berkeley. Accessed February 24, 2021.
http://www.escholarship.org/uc/item/5jh52309.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Polimeni, Rachel. “Health Insurance in Rural Cambodia: Impacts and Selection.” 2011. Web. 24 Feb 2021.
Vancouver:
Polimeni R. Health Insurance in Rural Cambodia: Impacts and Selection. [Internet] [Thesis]. University of California – Berkeley; 2011. [cited 2021 Feb 24].
Available from: http://www.escholarship.org/uc/item/5jh52309.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Polimeni R. Health Insurance in Rural Cambodia: Impacts and Selection. [Thesis]. University of California – Berkeley; 2011. Available from: http://www.escholarship.org/uc/item/5jh52309
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
11.
Schreiber, Sanja.
Schroth Exercises for Adolescent Idiopathic Scoliosis –
Reliability, A Randomized Controlled Trial and Clinical
Significance.
Degree: PhD, Faculty of Rehabilitation Medicine, 2015, University of Alberta
URL: https://era.library.ualberta.ca/files/cvx021f22r
► Background and objectives In America, care recommendations for adolescents with idiopathic scoliosis (AIS) include observation, bracing, and surgery. In Europe exercises are often prescribed. Schroth…
(more)
▼ Background and objectives In America, care
recommendations for adolescents with idiopathic scoliosis (AIS)
include observation, bracing, and surgery. In Europe exercises are
often prescribed. Schroth scoliosis-specific exercises have
demonstrated promising results, but only in studies of suboptimal
quality. Schroth exercise prescription is guided by curve
classification. An algorithm for determining Schroth curve types
was developed. Reporting statistical significance should be
supplemented with clinical significance estimates, which is rare
for research on conservative treatment for scoliosis. This thesis
aimed: 1) to determine the reliability of Schroth therapists in
classifying patients with AIS using the proposed algorithm; 2) to
investigate the effect of Schroth exercises combined with standard
of care on curve severity, qualityoflife (QOL), perceived
appearance and back muscle endurance compared to standard of care;
and 3) to determine the clinical significance of the effect of
Schroth exercises for all outcomes. Methods For the reliability
study, we recruited 44 participants with AIS and 10 consecutive
volunteer Schroth certified therapists. Therapists rated video
assessments presented randomly twice at least seven days apart
blinded to identities. The reliability was determined using Gwet’s
AC1 coefficients. For the RCT, we randomized 50 patients with AIS,
aged 10-18 years, with curves 10°45° to standard of care
(observation or bracing) or supervised Schroth exercises plus
standard of care. After introducing Schroth exercises, a daily home
program was adjusted during weekly supervised sessions for six
months. Assessors and the statistician were blinded. The primary
outcome was the change in the largest Cobb (LC) angle and the Sum
of Cobb (SOC) angles. Secondary outcomes included Biering-Sorensen
back muscle endurance test, Scoliosis Research Society (SRS22r) and
Spinal Appearance Questionnaires’ (SAQ) scores. Per protocol and
intention-to-treat linear mixed models analyses were reported.
Clinical significance was determined using anchor and
distribution-based methods. Numbers needed to treat (NNT), and
proportion of improved, stable and deteriorated patients were
reported. Results The overall intra-rater AC1 was 0.64 (95%CI
0.53-0.73), 0.70 (0.60-0.78) among well-trained raters, and 0.81
(0.77-0.85) in experienced raters. The weighted intra-rater AC1
averaged 0.75 (95%CI 0.63-0.84) overall, 0.82 (0.73-0.88) in
well-trained raters, and 0.89 (0.80-0.94) in experienced raters.
Inter-rater AC1 was 0.43 (95%CI 0.28-0.58) overall, 0.50
(0.38-0.61) for well-trained raters, and 0.67 (0.50-0.85) for
experienced raters. The weighted inter-rater AC1 was 0.48 (95%CI
0.29-0.67) overall, 0.61 (0.49-0.72) among well-trained, and 0.79
(0.64-0.94) among experienced raters. After six months, Schroth
group had by 3.5° (p<0.01) smaller LC in the per protocol
analysis. The difference in the square root of the SOC also favored
Schroth group (p<0.05) such that a patient with an average
51.2° SOC at baseline had a 49.3° at six…
Subjects/Keywords: Clinical significance; Randomized controlled trial; Reliability; Scoliosis; Schroth exercises
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APA (6th Edition):
Schreiber, S. (2015). Schroth Exercises for Adolescent Idiopathic Scoliosis –
Reliability, A Randomized Controlled Trial and Clinical
Significance. (Doctoral Dissertation). University of Alberta. Retrieved from https://era.library.ualberta.ca/files/cvx021f22r
Chicago Manual of Style (16th Edition):
Schreiber, Sanja. “Schroth Exercises for Adolescent Idiopathic Scoliosis –
Reliability, A Randomized Controlled Trial and Clinical
Significance.” 2015. Doctoral Dissertation, University of Alberta. Accessed February 24, 2021.
https://era.library.ualberta.ca/files/cvx021f22r.
MLA Handbook (7th Edition):
Schreiber, Sanja. “Schroth Exercises for Adolescent Idiopathic Scoliosis –
Reliability, A Randomized Controlled Trial and Clinical
Significance.” 2015. Web. 24 Feb 2021.
Vancouver:
Schreiber S. Schroth Exercises for Adolescent Idiopathic Scoliosis –
Reliability, A Randomized Controlled Trial and Clinical
Significance. [Internet] [Doctoral dissertation]. University of Alberta; 2015. [cited 2021 Feb 24].
Available from: https://era.library.ualberta.ca/files/cvx021f22r.
Council of Science Editors:
Schreiber S. Schroth Exercises for Adolescent Idiopathic Scoliosis –
Reliability, A Randomized Controlled Trial and Clinical
Significance. [Doctoral Dissertation]. University of Alberta; 2015. Available from: https://era.library.ualberta.ca/files/cvx021f22r
Vanderbilt University
12.
Gillespie, Amy Marie.
Writing to Learn in Science: Effects on Fourth-Grade Students' Understanding of Balance.
Degree: PhD, Special Education, 2014, Vanderbilt University
URL: http://hdl.handle.net/1803/12488
► In this study, 69 grade 4 students were randomly assigned to a writing to learn (n = 23), comparison (n = 23), or control (n…
(more)
▼ In this study, 69 grade 4 students were randomly assigned to a writing to learn (n = 23), comparison (n = 23), or control (n = 23) condition. In treatment and comparison, students made predictions and recorded results for 30 balance trials which involved different configurations of weights on an equal arm balance beam. Treatment students wrote 4 short answer responses about what they were learning during the trials and wrote an extended response after the trials about what they had learned about balance. To control for writing time, comparison students wrote 4 short answer responses about their favorite parts of the trials and wrote an extended response about their favorite parts of science class. Students in the control condition (n = 23) participated in business as usual classroom instruction. There were no statistically significant differences between treatment and comparison conditions on a 20-item balance knowledge posttest. However, students in the control condition outperformed students in the treatment (ES = 0.89) and comparison (ES = 1.05) on posttest questions at the lowest level of balance understanding (i.e., level 1). For balance knowledge questions at the highest levels, levels 3 and 4, the treatment condition (ESs = 1.42 and 0.94, respectively) and the comparison condition (ESs = 1.62 and 1.37, respectively) outperformed the control. No statistically significant differences were found between conditions for total words written and level of balance understanding on a posttest extended writing prompt. Implications of these findings and directions for future research on writing to learn are discussed.
Advisors/Committee Members: Lynn Fuchs (committee member), Deborah Rowe (committee member), Joseph Wehby (committee member), Donald Compton (Committee Chair), Steve Graham (Committee Chair).
Subjects/Keywords: writing to learn; science; elementary; Common Core; randomized controlled trial
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APA (6th Edition):
Gillespie, A. M. (2014). Writing to Learn in Science: Effects on Fourth-Grade Students' Understanding of Balance. (Doctoral Dissertation). Vanderbilt University. Retrieved from http://hdl.handle.net/1803/12488
Chicago Manual of Style (16th Edition):
Gillespie, Amy Marie. “Writing to Learn in Science: Effects on Fourth-Grade Students' Understanding of Balance.” 2014. Doctoral Dissertation, Vanderbilt University. Accessed February 24, 2021.
http://hdl.handle.net/1803/12488.
MLA Handbook (7th Edition):
Gillespie, Amy Marie. “Writing to Learn in Science: Effects on Fourth-Grade Students' Understanding of Balance.” 2014. Web. 24 Feb 2021.
Vancouver:
Gillespie AM. Writing to Learn in Science: Effects on Fourth-Grade Students' Understanding of Balance. [Internet] [Doctoral dissertation]. Vanderbilt University; 2014. [cited 2021 Feb 24].
Available from: http://hdl.handle.net/1803/12488.
Council of Science Editors:
Gillespie AM. Writing to Learn in Science: Effects on Fourth-Grade Students' Understanding of Balance. [Doctoral Dissertation]. Vanderbilt University; 2014. Available from: http://hdl.handle.net/1803/12488
McMaster University
13.
Goodall, Emma C.
Investigating Interventions for the Prevention of Upper Respiratory Tract Infections.
Degree: PhD, 2013, McMaster University
URL: http://hdl.handle.net/11375/13780
► Upper respiratory tract infection (URTI), which presents clinically as the common cold, is the most common form of respiratory illness experienced by humans and…
(more)
▼ Upper respiratory tract infection (URTI), which presents clinically as the common cold, is the most common form of respiratory illness experienced by humans and is a major cause of morbidity and hospitalizations. Currently, URTI prevention focuses on hand hygiene with some consideration given to other lifestyle factors such as sleep, nutrition, and exercise. Identifying additional interventions for the prevention of URTI could reduce the burden of this disease. In this thesis, I examine the role of vitamin D3 supplementation and tap water gargling for the prevention of URTI. I employ experimental and observational study designs to assess the effect of these interventions on the risk of URTI in the context of a randomized controlled trial of 600 participants, and a longitudinal cohort of 416 participants. Further, I investigate the association between modifiable lifestyle factors and risk of URTI using data from the longitudinal cohort. Data from this study is also used to explore statistical methods for the analysis of repeated events. When evaluating self-reported, clinical URTI, all analyses supported the use of vitamin D3 supplementation to reduce the risk of URTI. However, this finding was only statistically significant in the analysis of the longitudinal cohort study; results from the RCT indicated that vitamin D3 supplementation statistically significantly reduced the risk of laboratory confirmed infections but had a non-significant benefit for clinical infections. Gargling did not reduce the risk of clinical or laboratory confirmed infections.
Doctor of Philosophy (PhD)
Advisors/Committee Members: Smieja, Marek, Clinical Epidemiology/Clinical Epidemiology & Biostatistics.
Subjects/Keywords: rhinovirus; vitamin D; randomized controlled trial; gargling; Clinical Epidemiology; Clinical Epidemiology
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APA (6th Edition):
Goodall, E. C. (2013). Investigating Interventions for the Prevention of Upper Respiratory Tract Infections. (Doctoral Dissertation). McMaster University. Retrieved from http://hdl.handle.net/11375/13780
Chicago Manual of Style (16th Edition):
Goodall, Emma C. “Investigating Interventions for the Prevention of Upper Respiratory Tract Infections.” 2013. Doctoral Dissertation, McMaster University. Accessed February 24, 2021.
http://hdl.handle.net/11375/13780.
MLA Handbook (7th Edition):
Goodall, Emma C. “Investigating Interventions for the Prevention of Upper Respiratory Tract Infections.” 2013. Web. 24 Feb 2021.
Vancouver:
Goodall EC. Investigating Interventions for the Prevention of Upper Respiratory Tract Infections. [Internet] [Doctoral dissertation]. McMaster University; 2013. [cited 2021 Feb 24].
Available from: http://hdl.handle.net/11375/13780.
Council of Science Editors:
Goodall EC. Investigating Interventions for the Prevention of Upper Respiratory Tract Infections. [Doctoral Dissertation]. McMaster University; 2013. Available from: http://hdl.handle.net/11375/13780
14.
Schandelmaier, Stefan.
EVALUATING THE CREDIBILITY OF EFFECT MODIFICATION CLAIMS IN RANDOMIZED CONTROLLED TRIALS AND META-ANALYSES.
Degree: PhD, 2019, McMaster University
URL: http://hdl.handle.net/11375/24375
► Background: Many randomized controlled trials (RCTs) and meta-analyses include analyses of effect modification (also known as subgroup, interaction, or moderation analyses). Methodologists have widely acknowledged…
(more)
▼ Background: Many randomized controlled trials (RCTs) and meta-analyses include analyses of effect modification (also known as subgroup, interaction, or moderation analyses). Methodologists have widely acknowledged the challenges in deciding whether an apparent effect modification is credible or likely the result of chance or bias. Various sets of credibility criteria are available (Chapter 2 provides an example) but are inconsistent, vague in wording, lack guidance for deciding on overall credibility, and have not been systematically tested.
Objective: To systematically develop a formal instrument to assess the credibility of effect modification analyses (ICEMAN) in RCTs and meta-analyses of RCTs.
Methods: Key steps in the development process included 1) a systematic survey of the literature to identify available criteria, rationales, and previous instruments, 2) a formal consensus study among 10 leading experts, and 3) a formal user-testing study to refine the instrument based on interviews with trial investigators, systematic reviewer authors, and journal editors who applied drafts of the instrument to published claims of effect modification.
Results: The systematic survey identified 150 relevant publications, 36 candidate credibility criteria with associated rationales, and 30 existing checklists (Chapter 3). The consensus study consisted of two main video conferences and multiple rounds of written discussion. The user-testing involved 17 users (including systematic review authors, trial investigators, and journal editors) who suggested substantial improvements based on detailed interviews. The final instrument provides separate versions for RCTs (five core questions) and meta-analyses (eight core questions) with explicit response options, and an overall credibility rating ranging from very low to high credibility. A detailed manual provides rationales, supporting references, examples from the literature, and suggestions for use in combination with other quality appraisal tools and reporting (Chapter 4).
Discussion: ICEMAN is a rigorously developed instrument to evaluate claims of effect modification and addresses the main limitations of previous approaches.
Thesis
Doctor of Philosophy (PhD)
Randomized controlled trials and meta-analyses provide the best available evidence to evaluate whether effects of a therapy vary among individual patients. Efforts to decide whether treatment effects differ across patients are important and frequently done but difficult to interpret. The fundamental challenge is to decide whether apparent differences in effect are real or due to chance. To aid this decision, experts have suggested various sets of credibility criteria, all with important limitations. This thesis documents how we systematically addressed the limitations of previous approaches. Key steps were a systematic survey of the available credibility criteria, a consensus study among leading methodologists, and a formal user-testing study. The result is a new instrument for assessing the credibility…
Advisors/Committee Members: Guyatt, Gordon, Health Research Methodology.
Subjects/Keywords: randomized controlled trial; meta-analysis; effect modification; subgroup analysis
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APA (6th Edition):
Schandelmaier, S. (2019). EVALUATING THE CREDIBILITY OF EFFECT MODIFICATION CLAIMS IN RANDOMIZED CONTROLLED TRIALS AND META-ANALYSES. (Doctoral Dissertation). McMaster University. Retrieved from http://hdl.handle.net/11375/24375
Chicago Manual of Style (16th Edition):
Schandelmaier, Stefan. “EVALUATING THE CREDIBILITY OF EFFECT MODIFICATION CLAIMS IN RANDOMIZED CONTROLLED TRIALS AND META-ANALYSES.” 2019. Doctoral Dissertation, McMaster University. Accessed February 24, 2021.
http://hdl.handle.net/11375/24375.
MLA Handbook (7th Edition):
Schandelmaier, Stefan. “EVALUATING THE CREDIBILITY OF EFFECT MODIFICATION CLAIMS IN RANDOMIZED CONTROLLED TRIALS AND META-ANALYSES.” 2019. Web. 24 Feb 2021.
Vancouver:
Schandelmaier S. EVALUATING THE CREDIBILITY OF EFFECT MODIFICATION CLAIMS IN RANDOMIZED CONTROLLED TRIALS AND META-ANALYSES. [Internet] [Doctoral dissertation]. McMaster University; 2019. [cited 2021 Feb 24].
Available from: http://hdl.handle.net/11375/24375.
Council of Science Editors:
Schandelmaier S. EVALUATING THE CREDIBILITY OF EFFECT MODIFICATION CLAIMS IN RANDOMIZED CONTROLLED TRIALS AND META-ANALYSES. [Doctoral Dissertation]. McMaster University; 2019. Available from: http://hdl.handle.net/11375/24375
University of Nairobi
15.
Muviku, Victoria, M.
A Randomized Clinical Trial Comparing Oral and Vaginal Misoprostol for Induction of Labour at Term in Kenyatta National Hospital(K.n.h.)
.
Degree: 2016, University of Nairobi
URL: http://hdl.handle.net/11295/98858
► Introduction Induction of labour is the process of artificially stimulating the uterus so as to start labour. It’s usually done at the age of viability…
(more)
▼ Introduction
Induction of labour is the process of artificially stimulating the uterus so as to start labour. It’s usually done at the age of viability to avert a foreseen adverse outcome associated with continuation of the pregnancy. The indications for induction of labour differ. The incidence varies from country to country. In developed countries for instance, induction of labour varies between 20-35% but it has been found to be much lower in developing countries. In Niger for example, induction of labour is as low as 1.4%. Globally, an average of 9.6% of pregnant women will require induction of labour. Misoprostol (PGE1) has proved very effective in induction of labour. In addition, it’s cheap, heat stable therefore easy to store and transport and widely available. However, the ideal route of administration, dose and frequency are yet to be determined. Generally, women all over the world find vaginal examination uncomfortable. Therefore oral administration may be more comfortable and acceptable. A dose given less frequently than the current 2hourly solution will be better for the already constrained low resource settings.
Broad objective
To compare the efficacy of 25μg vaginal misoprostol 4hourly and 50μg oral misoprostol 4hourly for induction of labour, neonatal and maternal outcomes.
Methodology
Study participants were randomly assigned to 2 groups; oral misoprostol 50μg 4hourly and the other group assigned to vaginal misoprostol 25μg 4hourly to a maximum of 4 and 5doses respectively. The average duration from induction to delivery and proportion of deliveries occurring within 24hours of induction was determined. The primary dependent variable was the proportion of deliveries within 24hours of induction, while the secondary dependent variables were the maternal and perinatal outcomes. The independent variables include; the route and the dosage of administration of misoprostol and the socio-demographic characteristics.
x
Results
In this study, 77 study subjects received oral misoprostol while 75 received vaginal misoprostol for induction of labour. Among the participants who received vaginal misoprostol 52 (68.0) had a successful vaginal delivery within 24 hours compared to 40 (53.0%) of those that received oral misoprostol (P-value =0.09). The average duration taken from the onset of induction of labour until delivery was 17.9 hours for the participants who received oral misoprostol as compared to 21.7 hours in the group that received vaginal misoprostol (P-value =0.024). There was no statistically significant difference observed in the maternal and early perinatal outcomes between the two groups.
Conclusion
Oral misoprostol at 50μg 4hourly is as effective as vaginal misoprostol 25μg 4 hourly for induction of labour at term.
Subjects/Keywords: A Randomized Clinical Trial Comparing Oral and Vaginal Misoprostol
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APA (6th Edition):
Muviku, Victoria, M. (2016). A Randomized Clinical Trial Comparing Oral and Vaginal Misoprostol for Induction of Labour at Term in Kenyatta National Hospital(K.n.h.)
. (Thesis). University of Nairobi. Retrieved from http://hdl.handle.net/11295/98858
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Muviku, Victoria, M. “A Randomized Clinical Trial Comparing Oral and Vaginal Misoprostol for Induction of Labour at Term in Kenyatta National Hospital(K.n.h.)
.” 2016. Thesis, University of Nairobi. Accessed February 24, 2021.
http://hdl.handle.net/11295/98858.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Muviku, Victoria, M. “A Randomized Clinical Trial Comparing Oral and Vaginal Misoprostol for Induction of Labour at Term in Kenyatta National Hospital(K.n.h.)
.” 2016. Web. 24 Feb 2021.
Vancouver:
Muviku, Victoria M. A Randomized Clinical Trial Comparing Oral and Vaginal Misoprostol for Induction of Labour at Term in Kenyatta National Hospital(K.n.h.)
. [Internet] [Thesis]. University of Nairobi; 2016. [cited 2021 Feb 24].
Available from: http://hdl.handle.net/11295/98858.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Muviku, Victoria M. A Randomized Clinical Trial Comparing Oral and Vaginal Misoprostol for Induction of Labour at Term in Kenyatta National Hospital(K.n.h.)
. [Thesis]. University of Nairobi; 2016. Available from: http://hdl.handle.net/11295/98858
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
University of Toronto
16.
Workewych, Adriana Micheline.
TRANEXAMIC ACID IN THE TREATMENT OF RESIDUAL CHRONIC SUBDURAL HEMATOMA: A SINGLE-CENTRE, OBSERVER-BLINDED, RANDOMIZED CONTROLLED TRIAL (TRACE).
Degree: 2018, University of Toronto
URL: http://hdl.handle.net/1807/91377
► Chronic subdural hematoma (CSDH) is a frequent consequence of head trauma, particularly in older individuals. Given the aging of populations globally, its incidence is projected…
(more)
▼ Chronic subdural hematoma (CSDH) is a frequent consequence of head trauma, particularly in older individuals. Given the aging of populations globally, its incidence is projected to increase substantially. Hyperfibrinolysis may be central to CSDH enlargement by causing excessive clot degradation and liquefaction, impeding resorption. The only current standard treatment for CSDH is surgery, however, up to 31% of residual hematomas enlarge, requiring reoperation. Tranexamic acid (TXA), an antifibrinolytic medication that prevents excessively rapid clot breakdown, may help prevent CSDH enlargement, potentially eliminating the need for repeat surgery. To evaluate the feasibility of conducting a trial investigating TXA efficacy in residual CSDH, we conducted an observer-blinded, pilot randomized controlled trial (RCT). We showed this trial was feasible and safe, reporting only minor to moderate AEs, and an attrition rate of 4%. The results from this study will inform the conduct of a double-blinded RCT investigating TXA efficacy in post-operative CSDH management.
M.Sc.
Advisors/Committee Members: Cusimano, Michael D, Medical Science.
Subjects/Keywords: Chronic subdural hematoma; Randomized controlled trial; Tranexamic acid; 0317
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APA (6th Edition):
Workewych, A. M. (2018). TRANEXAMIC ACID IN THE TREATMENT OF RESIDUAL CHRONIC SUBDURAL HEMATOMA: A SINGLE-CENTRE, OBSERVER-BLINDED, RANDOMIZED CONTROLLED TRIAL (TRACE). (Masters Thesis). University of Toronto. Retrieved from http://hdl.handle.net/1807/91377
Chicago Manual of Style (16th Edition):
Workewych, Adriana Micheline. “TRANEXAMIC ACID IN THE TREATMENT OF RESIDUAL CHRONIC SUBDURAL HEMATOMA: A SINGLE-CENTRE, OBSERVER-BLINDED, RANDOMIZED CONTROLLED TRIAL (TRACE).” 2018. Masters Thesis, University of Toronto. Accessed February 24, 2021.
http://hdl.handle.net/1807/91377.
MLA Handbook (7th Edition):
Workewych, Adriana Micheline. “TRANEXAMIC ACID IN THE TREATMENT OF RESIDUAL CHRONIC SUBDURAL HEMATOMA: A SINGLE-CENTRE, OBSERVER-BLINDED, RANDOMIZED CONTROLLED TRIAL (TRACE).” 2018. Web. 24 Feb 2021.
Vancouver:
Workewych AM. TRANEXAMIC ACID IN THE TREATMENT OF RESIDUAL CHRONIC SUBDURAL HEMATOMA: A SINGLE-CENTRE, OBSERVER-BLINDED, RANDOMIZED CONTROLLED TRIAL (TRACE). [Internet] [Masters thesis]. University of Toronto; 2018. [cited 2021 Feb 24].
Available from: http://hdl.handle.net/1807/91377.
Council of Science Editors:
Workewych AM. TRANEXAMIC ACID IN THE TREATMENT OF RESIDUAL CHRONIC SUBDURAL HEMATOMA: A SINGLE-CENTRE, OBSERVER-BLINDED, RANDOMIZED CONTROLLED TRIAL (TRACE). [Masters Thesis]. University of Toronto; 2018. Available from: http://hdl.handle.net/1807/91377
Harvard University
17.
Ma, Wenjie.
Novel Nutritional and Lifestyle Factors for Cardiometabolic Risk in Prospective Cohorts and Randomized Clinical Trial.
Degree: Doctor of Science (SD), 2017, Harvard University
URL: http://nrs.harvard.edu/urn-3:HUL.InstRepos:42066829
► Cardiovascular disease (CVD) is the leading cause of death worldwide. Great advances have been made in identifying important cardiometabolic risk factors. More recently, emerging evidence…
(more)
▼ Cardiovascular disease (CVD) is the leading cause of death worldwide. Great advances have been made in identifying important cardiometabolic risk factors. More recently, emerging evidence has suggested several novel etiology pathways for CVD-of particular importance are gut microbiota and amino acids. In addition, despite that higher circulating adiponectin has been associated with reduced cardiometabolic risk in prospective studies, its role in the context of dietary intervention remains unclear. This has motivated my three dissertation projects in the identification of novel cardiometabolic risk factors related to the aforementioned pathways in prospective cohorts and randomized clinical trial.
Bowel movement frequency has been correlated with gut microbiota composition and other cardiometabolic risk factors. In Chapter one, we investigate whether bowel movement frequency is prospectively associated with risk of incident CVD and mortality in the Nurses’ Health Study. Compared to women with daily bowel movements, more frequent bowel movements were significantly associated with elevated cardiovascular risk, which may be partly explained by body mass index and diabetes. Increased bowel movement frequency was associated with a modest increase in the risk of total mortality independent of traditional risk factors.
Metabolomics profiling has identified circulating concentrations of glutamine, glutamate, and glutamine-to-glutamate ratio associated with risk of developing CVD and other cardiometabolic abnormalities. Chapter two prospectively examines dietary intakes of glutamine, glutamate, and their ratio in relation to total mortality and cause-specific mortality in the Nurses’ Health Study and Health Professionals Follow-up Study. Data from two cohorts consistently showed that dietary intakes of glutamine and glutamine-to-glutamate ratio were inversely related to mortality particularly cardiovascular mortality, independent of other dietary and lifestyle factors.
The beneficial effects of weight-loss diet interventions on improvement of cardiometabolic risk may be partly through modulating secretion of adiponectin. Chapter three assesses the effects of long-term weight-loss diets with different compositions of macronutrients on longitudinal changes in circulating adiponectin concentrations and how such changes, if they exist, affect cardiometabolic risk. In the 2-year Preventing Overweight Using Novel Dietary Strategies Trial, long-term interventions by weight-loss diets varying in macronutrients similarly increased circulating adiponectin, which might particularly improve body adiposity, abdominal fat distribution, and lipid profile.
Epidemiology
Advisors/Committee Members: Qi, Lu (advisor), Rimm, Eric B. (committee member), Sacks, Frank M. (committee member), Wang, Molin (committee member).
Subjects/Keywords: Cardiovascular risk factor; lifestyle; nutrition; cohort; randomized clinical trial
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APA (6th Edition):
Ma, W. (2017). Novel Nutritional and Lifestyle Factors for Cardiometabolic Risk in Prospective Cohorts and Randomized Clinical Trial. (Doctoral Dissertation). Harvard University. Retrieved from http://nrs.harvard.edu/urn-3:HUL.InstRepos:42066829
Chicago Manual of Style (16th Edition):
Ma, Wenjie. “Novel Nutritional and Lifestyle Factors for Cardiometabolic Risk in Prospective Cohorts and Randomized Clinical Trial.” 2017. Doctoral Dissertation, Harvard University. Accessed February 24, 2021.
http://nrs.harvard.edu/urn-3:HUL.InstRepos:42066829.
MLA Handbook (7th Edition):
Ma, Wenjie. “Novel Nutritional and Lifestyle Factors for Cardiometabolic Risk in Prospective Cohorts and Randomized Clinical Trial.” 2017. Web. 24 Feb 2021.
Vancouver:
Ma W. Novel Nutritional and Lifestyle Factors for Cardiometabolic Risk in Prospective Cohorts and Randomized Clinical Trial. [Internet] [Doctoral dissertation]. Harvard University; 2017. [cited 2021 Feb 24].
Available from: http://nrs.harvard.edu/urn-3:HUL.InstRepos:42066829.
Council of Science Editors:
Ma W. Novel Nutritional and Lifestyle Factors for Cardiometabolic Risk in Prospective Cohorts and Randomized Clinical Trial. [Doctoral Dissertation]. Harvard University; 2017. Available from: http://nrs.harvard.edu/urn-3:HUL.InstRepos:42066829
University of Guelph
18.
Charles, Christopher.
Happy Fish: A Novel Supplementation Technique to Prevent Iron Deficiency Anemia in Women in Rural Cambodia.
Degree: PhD, Department of Biomedical Sciences, 2013, University of Guelph
URL: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/5927
► Maternal and child undernutrition are a significant problem in the developing world, with serious consequences for human health and socio-economic development. In Cambodia, 55% of…
(more)
▼ Maternal and child undernutrition are a significant problem in the developing world, with serious consequences for human health and socio-economic development. In Cambodia, 55% of children, 43% of women of reproductive age, and 50% of pregnant women are anemic. Current prevention and control practices rely on supplementation with iron pills or large-scale food fortification, neither of which are affordable or feasible in rural Cambodia. In the study areas, 97% of women did not meet their daily iron requirements. The current research focuses on the design and evaluation of an innovative iron supplementation technique. A culturally acceptable, inexpensive and lightweight iron ingot was designed to resemble a fish species considered lucky in Khmer culture. The ingot, referred to as ‘try sabay’ or ‘happy fish’, was designed to supply iron at a slow, steady rate. Iron leaching was observed in water and soup samples prepared with the iron fish when used concurrently with an acidifier. More than 75% of daily iron requirements can be met with regular use. Its use in the common pot of soup or boiled water provides supplementation to the entire family. The effectiveness of the iron fish was investigated in a
randomized community
trial involving 310 women in rural Cambodia. Blood samples were taken at baseline and every three months thereafter, over a 12-month
trial period. Significant increases in hemoglobin concentrations were observed in women allocated an iron fish when compared to controls throughout the study, with an endline difference of 11.6 g/L. Significant improvements in serum ferritin concentration were observed at 9 months (6.9 ng/mL) and endline (30.8 ng/mL) in women who used an iron fish regularly when compared to the control group. Overall, use of the iron fish led to a two-fold reduction in the prevalence of anemia. The supplement was used daily by 94% of the households at the end of the
trial. The study highlights the acceptability and effectiveness of a fish-shaped iron ingot as a means of improving dietary iron content. It offers a promising, simple solution to iron deficiency anemia if the project can be scaled-up for use throughout the country.
Advisors/Committee Members: Summerlee, Alastair (advisor), Dewey, Cate (advisor).
Subjects/Keywords: Anemia; Nutrition; Iron Fish; Cambodia; Randomized controlled trial
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APA (6th Edition):
Charles, C. (2013). Happy Fish: A Novel Supplementation Technique to Prevent Iron Deficiency Anemia in Women in Rural Cambodia. (Doctoral Dissertation). University of Guelph. Retrieved from https://atrium.lib.uoguelph.ca/xmlui/handle/10214/5927
Chicago Manual of Style (16th Edition):
Charles, Christopher. “Happy Fish: A Novel Supplementation Technique to Prevent Iron Deficiency Anemia in Women in Rural Cambodia.” 2013. Doctoral Dissertation, University of Guelph. Accessed February 24, 2021.
https://atrium.lib.uoguelph.ca/xmlui/handle/10214/5927.
MLA Handbook (7th Edition):
Charles, Christopher. “Happy Fish: A Novel Supplementation Technique to Prevent Iron Deficiency Anemia in Women in Rural Cambodia.” 2013. Web. 24 Feb 2021.
Vancouver:
Charles C. Happy Fish: A Novel Supplementation Technique to Prevent Iron Deficiency Anemia in Women in Rural Cambodia. [Internet] [Doctoral dissertation]. University of Guelph; 2013. [cited 2021 Feb 24].
Available from: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/5927.
Council of Science Editors:
Charles C. Happy Fish: A Novel Supplementation Technique to Prevent Iron Deficiency Anemia in Women in Rural Cambodia. [Doctoral Dissertation]. University of Guelph; 2013. Available from: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/5927
University of Connecticut
19.
Thacker, Sejal R.
Immediate Versus Delayed Loading of Two Implants Supporting A Locator Retained Mandibular Overdenture. A Randomized Controlled Study.
Degree: Master of Dental Science, Dental Science, 2012, University of Connecticut
URL: https://opencommons.uconn.edu/gs_theses/305
► The aim of this study was to evaluate immediate versus delayed loading of two implants, six months post-surgery, supporting a locator retained mandibular overdenture.…
(more)
▼ The aim of this study was to evaluate immediate versus delayed loading of two implants, six months post-surgery, supporting a locator retained mandibular overdenture. The objective was to evaluate implant bone remodelling using radiographic bone level changes (RBL) as the variable, from baseline to six months, between the test and the control groups. The secondary objectives included (1) evaluation of implant survival, (2) nature and frequency of surgical and prosthetic complications, and (3) correlation of implant length and insertion torque on RBL.
Eligible patients were
randomized into test (immediate loading) and control group (delayed loading). Five patients were allocated to control group and seven to the test. All patients had two implants placed. The test group had implants loaded immediately. Baseline standardized radiographs were taken following surgery. The control group had the implants submerged, which were loaded at three months post surgery. The patients were followed up for six months and radiographs were retaken at six months to evaluate RBL. Patient and implant level analysis was done.
2/14 implants failed in the immediate loading group and no failures were seen in the delayed loading group. RBL between the groups was not statistically significant. RBL within the groups was statistically significant. Number of maintenance visits required for either group was not statistically significant. Insertion torque and implant length did not seem to effect bone level changes.
The marginal bone level changes around immediately loaded implants are comparable to those seen around implants loaded with a delayed protocol, at 6 months post surgery.
Advisors/Committee Members: Efthimia Ioannidou, Thomas Taylor, Khalid Almas, Gian Pietro Schincaglia.
Subjects/Keywords: overdenture; immediate loading; locator; delayed loading; mandible; edntulous; randomized controlled trial
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APA (6th Edition):
Thacker, S. R. (2012). Immediate Versus Delayed Loading of Two Implants Supporting A Locator Retained Mandibular Overdenture. A Randomized Controlled Study. (Masters Thesis). University of Connecticut. Retrieved from https://opencommons.uconn.edu/gs_theses/305
Chicago Manual of Style (16th Edition):
Thacker, Sejal R. “Immediate Versus Delayed Loading of Two Implants Supporting A Locator Retained Mandibular Overdenture. A Randomized Controlled Study.” 2012. Masters Thesis, University of Connecticut. Accessed February 24, 2021.
https://opencommons.uconn.edu/gs_theses/305.
MLA Handbook (7th Edition):
Thacker, Sejal R. “Immediate Versus Delayed Loading of Two Implants Supporting A Locator Retained Mandibular Overdenture. A Randomized Controlled Study.” 2012. Web. 24 Feb 2021.
Vancouver:
Thacker SR. Immediate Versus Delayed Loading of Two Implants Supporting A Locator Retained Mandibular Overdenture. A Randomized Controlled Study. [Internet] [Masters thesis]. University of Connecticut; 2012. [cited 2021 Feb 24].
Available from: https://opencommons.uconn.edu/gs_theses/305.
Council of Science Editors:
Thacker SR. Immediate Versus Delayed Loading of Two Implants Supporting A Locator Retained Mandibular Overdenture. A Randomized Controlled Study. [Masters Thesis]. University of Connecticut; 2012. Available from: https://opencommons.uconn.edu/gs_theses/305
University of Connecticut
20.
Bruneau, Michael L, Jr.
A Meta-Analysis of Candidate Gene Association Studies on the Blood Pressure Response to Aerobic Exercise.
Degree: MS, Kinesiology, 2013, University of Connecticut
URL: https://opencommons.uconn.edu/gs_theses/431
► ABSTRACT Purpose: Aerobic exercise (AE) lowers blood pressure (BP) 5-7 mmHg among those with hypertension, but there is considerable variability in the BP response…
(more)
▼ ABSTRACT
Purpose: Aerobic exercise (AE) lowers blood pressure (BP) 5-7 mmHg among those with hypertension, but there is considerable variability in the BP response to AE. Genetic predispositions account for 40-65% of this variability; however, identifying genetic variants that associate with the BP response to AE is a challenge. We performed a meta-analysis to integrate the small number of studies that examined the influence of candidate genes on the BP response to AE. Methods: Studies retrieved included an acute or chronic AE intervention; BP before and after AE by genotype; and candidate gene polymorphisms. Effect sizes were the standardized mean difference of BP post-vs. pre-exercise for AE training interventions, and post-vs. pre-exercise BP vs. control for acute AE interventions. Effect sizes were disaggregated for genotype and adjusted for baseline sample features. Analyses followed fixed‑effects assumptions. Results: 11 AE training (
N=2646) and 4 acute AE (
N=50) studies qualified. AE training interventions were performed at 62.3±7.5% (Mean+SD) maximum oxygen consumption for 43.8±11.6 min×session
-1,3.6±1.2 d×wk
-1 for 15.3±7.6 wk. Participants were mostly non-Hispanic white (
N=1,736) men (
N=1,278) and women (
N=1,360), 44.2±10.7 yr with a BP of 134.4±11.9/78.6±9.3 mmHg and body mass index of 26.9±2.6 kg.m
-2. The effect of exercise on the BP response to AE training was small but statistically significant for systolic BP (SBP) (<em>d
+ = </em>-0.21 [95% CI = -0.247, -0.168], -3.1 mmHg,
I2=77.8%) and diastolic BP (DBP) (<em>d
+ = </em>‑0.20 [95% CI = -0.235, -0.158], -1.9 mmHg,
I2=62.2%). Sample features explained 59.1-71.5% of the variability in the BP response to AE training (
P< 0.001), and reductions were greater among samples that had a higher resting BP (SBP: β
= -0.68, <em>P< </em>0.001; DBP: β=-0.56,
P=0.01), that were younger (SBP: β
=0.34, <em>P<</em>0.01; DBP: NS, <em>P></em>0.05), and that included more women than men (SBP: β = 0.41, <em>P<</em>0.001; DBP: β=0.52,
PAGT) M235T (rs699) polymorphism showed a significant association with the DBP response to AE training (Multiple
R=0.058,
P=0.02), explaining 0.3% of the variability in the DBP response. Pairwise comparisons of
AGT M235T genotypes showed those with the
AGT MM genotype reduced DBP 2.9 mmHg more in response to AE training compared to those with the
AGT TT genotype (Multiple
R=0.076,
P=0.02). Acute interventions were performed at 50.1±10.1% maximum oxygen consumption for 40 min·session
-1. Participants were men, 44.1±1.0 yr with a BP of 145.7±1.7 / 85.8±0.9 mmHg and body mass index of 29.9±0.3 kg.m
-2. BP responses to acute AE were large and heterogeneous for SBP (<em>d
+ = </em>-0.62 [95% CI = ‑0.75,…
Advisors/Committee Members: Blair T. Johnson and Tania B. Huedo-Medina, Linda S. Pescatello.
Subjects/Keywords: Blood Pressure; Exercise; Randomized Control Trial; and Genes
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APA (6th Edition):
Bruneau, Michael L, J. (2013). A Meta-Analysis of Candidate Gene Association Studies on the Blood Pressure Response to Aerobic Exercise. (Masters Thesis). University of Connecticut. Retrieved from https://opencommons.uconn.edu/gs_theses/431
Chicago Manual of Style (16th Edition):
Bruneau, Michael L, Jr. “A Meta-Analysis of Candidate Gene Association Studies on the Blood Pressure Response to Aerobic Exercise.” 2013. Masters Thesis, University of Connecticut. Accessed February 24, 2021.
https://opencommons.uconn.edu/gs_theses/431.
MLA Handbook (7th Edition):
Bruneau, Michael L, Jr. “A Meta-Analysis of Candidate Gene Association Studies on the Blood Pressure Response to Aerobic Exercise.” 2013. Web. 24 Feb 2021.
Vancouver:
Bruneau, Michael L J. A Meta-Analysis of Candidate Gene Association Studies on the Blood Pressure Response to Aerobic Exercise. [Internet] [Masters thesis]. University of Connecticut; 2013. [cited 2021 Feb 24].
Available from: https://opencommons.uconn.edu/gs_theses/431.
Council of Science Editors:
Bruneau, Michael L J. A Meta-Analysis of Candidate Gene Association Studies on the Blood Pressure Response to Aerobic Exercise. [Masters Thesis]. University of Connecticut; 2013. Available from: https://opencommons.uconn.edu/gs_theses/431
Kwame Nkrumah University of Science and Technology
21.
Phillips, Richard O.; Robert, Jerome; Abass, K. Mohamed; Thompson, William; Sarfo, F. Stephen.
Randomised trial to compare clarithromycin (extended release)- rifampicin and streptomycin-rifampicin for early, limited lesions of M. ulcerans infection.
Degree: 2019, Kwame Nkrumah University of Science and Technology
URL: The
Lancet,
SSRN:
https://ssrn.com/abstract=3458507
;
http://dspace.knust.edu.gh:8080/jspui/handle/123456789/11952
► Background Buruli ulcer (Mycobacterium ulcerans infection) is a Neglected Tropical Disease characterised by severe subcutaneous necrosis, with occasional bone involvement. Being reported from 33 countries,…
(more)
▼ Background Buruli ulcer (Mycobacterium ulcerans infection) is a Neglected
Tropical Disease characterised by severe subcutaneous necrosis, with
occasional bone involvement. Being reported from 33 countries, it is most
prevalent in West and Central Africa, and Australia. In Africa, the major
burden is borne by poor rural children. If left untreated, Buruli ulcer
may progress to cause severe suffering and ultimately stigmatising
disability resulting in school drop-out and loss of income. Standard
antimicrobial treatment with oral rifampicin 10 mg/kg and intramuscular
streptomycin 15 mg/kg for eight weeks (RS8) is highly effective but
streptomycin injections are painful and may cause hearing loss.
Methods Between January 2013 and December 2017, we conducted an open
label randomised multicentre phase III clinical trial with noninferiority
design comparing fully oral treatment with rifampicin and
clarithromycin 15 mg/kg extended release (RC8) with RS8. A sample size of
332 participants was calculated to detect inferiority of CR8 by a margin
of 12%.
An article published by The Lancet
KNUST
Subjects/Keywords: Buruli ulcer; Mycobacterium ulcerans; drug treatment; randomized clinical trial
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APA (6th Edition):
Phillips, Richard O.; Robert, Jerome; Abass, K. Mohamed; Thompson, William; Sarfo, F. S. (2019). Randomised trial to compare clarithromycin (extended release)- rifampicin and streptomycin-rifampicin for early, limited lesions of M. ulcerans infection. (Thesis). Kwame Nkrumah University of Science and Technology. Retrieved from The Lancet, SSRN: https://ssrn.com/abstract=3458507 ; http://dspace.knust.edu.gh:8080/jspui/handle/123456789/11952
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Phillips, Richard O.; Robert, Jerome; Abass, K. Mohamed; Thompson, William; Sarfo, F Stephen. “Randomised trial to compare clarithromycin (extended release)- rifampicin and streptomycin-rifampicin for early, limited lesions of M. ulcerans infection.” 2019. Thesis, Kwame Nkrumah University of Science and Technology. Accessed February 24, 2021.
The Lancet, SSRN: https://ssrn.com/abstract=3458507 ; http://dspace.knust.edu.gh:8080/jspui/handle/123456789/11952.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Phillips, Richard O.; Robert, Jerome; Abass, K. Mohamed; Thompson, William; Sarfo, F Stephen. “Randomised trial to compare clarithromycin (extended release)- rifampicin and streptomycin-rifampicin for early, limited lesions of M. ulcerans infection.” 2019. Web. 24 Feb 2021.
Vancouver:
Phillips, Richard O.; Robert, Jerome; Abass, K. Mohamed; Thompson, William; Sarfo FS. Randomised trial to compare clarithromycin (extended release)- rifampicin and streptomycin-rifampicin for early, limited lesions of M. ulcerans infection. [Internet] [Thesis]. Kwame Nkrumah University of Science and Technology; 2019. [cited 2021 Feb 24].
Available from: The Lancet, SSRN: https://ssrn.com/abstract=3458507 ; http://dspace.knust.edu.gh:8080/jspui/handle/123456789/11952.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Phillips, Richard O.; Robert, Jerome; Abass, K. Mohamed; Thompson, William; Sarfo FS. Randomised trial to compare clarithromycin (extended release)- rifampicin and streptomycin-rifampicin for early, limited lesions of M. ulcerans infection. [Thesis]. Kwame Nkrumah University of Science and Technology; 2019. Available from: The Lancet, SSRN: https://ssrn.com/abstract=3458507 ; http://dspace.knust.edu.gh:8080/jspui/handle/123456789/11952
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
22.
Bolton, Shay-Lee.
Evaluation of a gatekeeper training program as suicide intervention training for medical students: a randomized controlled trial.
Degree: Community Health Sciences, 2015, University of Manitoba
URL: http://hdl.handle.net/1993/30725
► Most individuals who die by suicide have contact with a physician in the year before their death. There are no randomized trials that have evaluated…
(more)
▼ Most individuals who die by suicide have contact with a physician in the year before their death. There are no
randomized trials that have evaluated suicide intervention training for medical students or physicians. The objective of this study was to determine the effectiveness of a gatekeeper training program on suicide intervention behavior using Objective Structured Clinical Examinations (OSCEs) in medical students. A
randomized controlled
trial design was used. Participants were 112 undergraduate medical students at the University of Manitoba. The 2-day Applied Suicide Intervention Skills Training (ASIST) program was completed by half of the participants, according to a stratified block randomization design. Scores on OSCEs and scores on the Suicide Intervention Response Inventory (SIRI-2) were used as objective measures of intervention behaviors. There was a a significant Group-by-Time interaction on OSCE data, demonstrating that medical students who received ASIST performed significantly better than medical students who received training as usual (p<.001). The two groups did not differ significantly from each other on the SIRI-2 (p=.78). ASIST training improved the ability of medical students to detect and intervene with a standardized suicidal patient as assessed by OSCEs, compared to medical school training as usual. This study provides support for ASIST training for medical students to develop skills in recognition and management of suicidal patients.
Advisors/Committee Members: Elias, Brenda (Community Health Sciences) (supervisor), Sareen, Jitender (Community Health Sciences).
Subjects/Keywords: Medical students; ASIST; Suicide; Prevention; Training; Randomized controlled trial; OSCE
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Manager
APA (6th Edition):
Bolton, S. (2015). Evaluation of a gatekeeper training program as suicide intervention training for medical students: a randomized controlled trial. (Thesis). University of Manitoba. Retrieved from http://hdl.handle.net/1993/30725
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Bolton, Shay-Lee. “Evaluation of a gatekeeper training program as suicide intervention training for medical students: a randomized controlled trial.” 2015. Thesis, University of Manitoba. Accessed February 24, 2021.
http://hdl.handle.net/1993/30725.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Bolton, Shay-Lee. “Evaluation of a gatekeeper training program as suicide intervention training for medical students: a randomized controlled trial.” 2015. Web. 24 Feb 2021.
Vancouver:
Bolton S. Evaluation of a gatekeeper training program as suicide intervention training for medical students: a randomized controlled trial. [Internet] [Thesis]. University of Manitoba; 2015. [cited 2021 Feb 24].
Available from: http://hdl.handle.net/1993/30725.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Bolton S. Evaluation of a gatekeeper training program as suicide intervention training for medical students: a randomized controlled trial. [Thesis]. University of Manitoba; 2015. Available from: http://hdl.handle.net/1993/30725
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
University of Ottawa
23.
McNally, James Dayre.
The Role of Daily High Dose Vitamin D In the Prevention of Post-Operative Vitamin D Deficiency In Children with Congenital Heart Disease
.
Degree: 2015, University of Ottawa
URL: http://hdl.handle.net/10393/33171
► Background: With usual supplementation practices, most children are Vitamin D Deficient (VDD) following Congenital Heart Disease (CHD) surgery and alternative regimens need consideration. Methods/Results: i)…
(more)
▼ Background: With usual supplementation practices, most children are Vitamin D Deficient (VDD) following Congenital Heart Disease (CHD) surgery and alternative regimens need consideration. Methods/Results: i) A systematic review identified 88 pediatric trials of high dose vitamin D. Studies evaluating the Institute of Medicine (IOM) Tolerable Upper Intake Level (UL) did not rapidly normalize levels, while loading therapy (≥ 40000 IU) did so within 3 days. Hypercalcemia occurred more often with doses above 400000 IU. ii) A double blind RCT was designed to determine whether pre-operative administration of the IOM UL can prevent post-operative VDD. Results after the first 30 participants completed study procedures demonstrated it was possible to recruit (1.8 patients per month) and complete study procedures (i.e. blood collection). Unfortunately few participants (45%) received more than 30 doses of study drug. Conclusion: Prevention of post-operative VDD in the majority of CHD patients will require alternatives to the IOM recommendations.
Subjects/Keywords: Congenital Heart Disease;
Vitamin D;
Systematic Review;
Randomized Controlled Trial
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APA (6th Edition):
McNally, J. D. (2015). The Role of Daily High Dose Vitamin D In the Prevention of Post-Operative Vitamin D Deficiency In Children with Congenital Heart Disease
. (Thesis). University of Ottawa. Retrieved from http://hdl.handle.net/10393/33171
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
McNally, James Dayre. “The Role of Daily High Dose Vitamin D In the Prevention of Post-Operative Vitamin D Deficiency In Children with Congenital Heart Disease
.” 2015. Thesis, University of Ottawa. Accessed February 24, 2021.
http://hdl.handle.net/10393/33171.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
McNally, James Dayre. “The Role of Daily High Dose Vitamin D In the Prevention of Post-Operative Vitamin D Deficiency In Children with Congenital Heart Disease
.” 2015. Web. 24 Feb 2021.
Vancouver:
McNally JD. The Role of Daily High Dose Vitamin D In the Prevention of Post-Operative Vitamin D Deficiency In Children with Congenital Heart Disease
. [Internet] [Thesis]. University of Ottawa; 2015. [cited 2021 Feb 24].
Available from: http://hdl.handle.net/10393/33171.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
McNally JD. The Role of Daily High Dose Vitamin D In the Prevention of Post-Operative Vitamin D Deficiency In Children with Congenital Heart Disease
. [Thesis]. University of Ottawa; 2015. Available from: http://hdl.handle.net/10393/33171
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Syracuse University
24.
Malandrino, Rigby Dawn.
Generalization Programming and Performance Feedback: A Writing Intervention with Third-Grade Students.
Degree: PhD, Psychology, 2017, Syracuse University
URL: https://surface.syr.edu/etd/834
► Despite the importance of explicitly programming generalization in the context of intervention studies (Stokes & Osnes, 1989), the research base is limited, especially with…
(more)
▼ Despite the importance of explicitly programming generalization in the context of intervention studies (Stokes & Osnes, 1989), the research base is limited, especially with respect to academic interventions. Given that writing is a particular area of concern in the United States (National Center for Education Statistics, 2012), this is an important area to target. As such, the purpose of this study was to examine the benefit of incorporating explicit generalization programming tactics into a performance feedback intervention that has received support for increasing students’ writing fluency (Hier & Eckert, 2014). Toward this aim, 52 third-grade students were randomly assigned to one of two conditions: (a) performance feedback, or (b) performance feedback with generalization programming. Four generalization assessments were administered during pre- and post-assessment phases. It was hypothesized that students receiving performance feedback with generalization programming tactics would outperform a condition receiving performance feedback alone across the generalization assessments. This hypothesis was not supported for any of the generalization assessments. Rather, students in both conditions demonstrated similar improvements in their post-assessment writing performance. As such, in the context of this study, there was not a significant benefit added to the performance feedback intervention by including generalization programming tactics.
Advisors/Committee Members: Tanya L. Eckert.
Subjects/Keywords: academic intervention; generalization programming; randomized trial; writing; Social and Behavioral Sciences
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APA ·
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MLA ·
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Manager
APA (6th Edition):
Malandrino, R. D. (2017). Generalization Programming and Performance Feedback: A Writing Intervention with Third-Grade Students. (Doctoral Dissertation). Syracuse University. Retrieved from https://surface.syr.edu/etd/834
Chicago Manual of Style (16th Edition):
Malandrino, Rigby Dawn. “Generalization Programming and Performance Feedback: A Writing Intervention with Third-Grade Students.” 2017. Doctoral Dissertation, Syracuse University. Accessed February 24, 2021.
https://surface.syr.edu/etd/834.
MLA Handbook (7th Edition):
Malandrino, Rigby Dawn. “Generalization Programming and Performance Feedback: A Writing Intervention with Third-Grade Students.” 2017. Web. 24 Feb 2021.
Vancouver:
Malandrino RD. Generalization Programming and Performance Feedback: A Writing Intervention with Third-Grade Students. [Internet] [Doctoral dissertation]. Syracuse University; 2017. [cited 2021 Feb 24].
Available from: https://surface.syr.edu/etd/834.
Council of Science Editors:
Malandrino RD. Generalization Programming and Performance Feedback: A Writing Intervention with Third-Grade Students. [Doctoral Dissertation]. Syracuse University; 2017. Available from: https://surface.syr.edu/etd/834
Univerzitet u Beogradu
25.
Nedeljković, Una, 1972-.
Uticaj rehabilitacije na oporavak osoba sa multiplom
sklerozom posle akutnog pogoršanja bolesti.
Degree: Medicinski fakultet, 2015, Univerzitet u Beogradu
URL: https://fedorabg.bg.ac.rs/fedora/get/o:9663/bdef:Content/get
► Medicina - Neurorehabilitacija / Medicine - Neurorehabilitation
Uvod: Periodična pojava relapsa bolesti predstavlja jednu od glavnih karakteristika multiple skleroze, a manifestuje se iznenadnim pogoršanjem neurološkog…
(more)
▼ Medicina - Neurorehabilitacija / Medicine -
Neurorehabilitation
Uvod: Periodična pojava relapsa bolesti predstavlja
jednu od glavnih karakteristika multiple skleroze, a manifestuje se
iznenadnim pogoršanjem neurološkog stanja bolesnika. Zlatni
standard u terapiji ovih akutnih pogoršanja bolesti je primena
visokih doza intravenskog metilprednizolona. Istraživanja su,
međutim, pokazala da je oporavak bolesnika posle primene ove
terapije nepotpun. Zaostajanje određenog stepena oneposobljenosti,
perzistiranje simptoma i njihov uticaj na aktivnosti svakodnevnog
života, kao i redukovan kvalitet života obolelih, često su prisutni
duži vremenski period nakon završene medikamentne terapije. Cilj
ovog istraživanja je bio da utvrdi da li multidisciplinarna
rehabilitacija u kombinaciji sa primenom visokih doza
kortikosteroida kod osoba sa multiplom sklerozom u akutnom
pogoršanju bolesti, dovodi do boljeg oporavka u odnosu na izolovanu
primenu kortikosteroida. Metodologija: Istraživanje je sprovedeno u
vidu randomizovanog kliničkog ispitivanja. 49 ispitanika je
uključeno u studiju i randomizovano u eksperimentalnu i kontrolnu
grupu, a 37 je završilo ispitivanje. Svi bolesnici su primili
kortikostroidnu terapiju, a eksperimentalna grupa je dodatno
uključena u multidisciplinarni rehabilitaconi program u trajanju od
3 nedelje. Ishodne varijable su bile : Proširena skala funkcionalne
onesposobljenosti (EDSS), Skala za procenu funkcionalne
nezavisnosti(FIM), Bekov upitnik za procenu depresije (BDI) , Skala
težine zamora (FSS) i Upitnik za procenu kvaliteta života obolelih
od multiple skleroze ( MSQoL54). Procena oporavka vršena je posle
mesec dana i tri meseca od primene medikamentne terapije.
Rezultati: Statistički značajno poboljšanje EDSS i FIM skora
prisutno je u obe grupe posle mesec dana i tri meseca, ali bez
statistički značajne razlike promene skora među grupama. BDI skor
pokazuje statistički značajnu promenu vrednosti samo u
eksperimentalnoj grupi u oba vremena praćenja, ali se u poređenju
sa kontrolnom grupom ne uočava statistički značajna razlika. FSS
pokazuje potpuno različi trend kretanja vrednosti u grupama, ali
bez statističke značajnosti promene vrednosti kako unutar grupe,
tako i među grupama. Kvalitet života značajno je poboljšan u
eksperimentalnoj grupi. Za razliku od kontrolne grupe gde je
poboljšanje postignuto samo u fizičkom kompozitnom skoru i to sa
srednjom veličinom efekta, u eksperimentalnoj grupi poboljšanje je
postignuto i u fizičkom i u mentalnom kompozitnom skoru, sa
izraženom veličinom efekta, naročito posle trećeg
meseca...
Advisors/Committee Members: Drulović, Jelena, 1960-.
Subjects/Keywords: multiple sclerosis; relapse; methylprednisolon;
multidisciplinary rehabilitation; randomized controlled
trial
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APA ·
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CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Nedeljković, Una, 1. (2015). Uticaj rehabilitacije na oporavak osoba sa multiplom
sklerozom posle akutnog pogoršanja bolesti. (Thesis). Univerzitet u Beogradu. Retrieved from https://fedorabg.bg.ac.rs/fedora/get/o:9663/bdef:Content/get
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Nedeljković, Una, 1972-. “Uticaj rehabilitacije na oporavak osoba sa multiplom
sklerozom posle akutnog pogoršanja bolesti.” 2015. Thesis, Univerzitet u Beogradu. Accessed February 24, 2021.
https://fedorabg.bg.ac.rs/fedora/get/o:9663/bdef:Content/get.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Nedeljković, Una, 1972-. “Uticaj rehabilitacije na oporavak osoba sa multiplom
sklerozom posle akutnog pogoršanja bolesti.” 2015. Web. 24 Feb 2021.
Vancouver:
Nedeljković, Una 1. Uticaj rehabilitacije na oporavak osoba sa multiplom
sklerozom posle akutnog pogoršanja bolesti. [Internet] [Thesis]. Univerzitet u Beogradu; 2015. [cited 2021 Feb 24].
Available from: https://fedorabg.bg.ac.rs/fedora/get/o:9663/bdef:Content/get.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Nedeljković, Una 1. Uticaj rehabilitacije na oporavak osoba sa multiplom
sklerozom posle akutnog pogoršanja bolesti. [Thesis]. Univerzitet u Beogradu; 2015. Available from: https://fedorabg.bg.ac.rs/fedora/get/o:9663/bdef:Content/get
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Univerzitet u Beogradu
26.
Mitrović, Dragica N., 1962-.
Delotvornost dodatnog kineziterapijskog programa za
funkcionalno vežbanje ruku na kvalitet života nakon operativnog
lečenja osteoartritisa kuka.
Degree: Medicinski fakultet, 2016, Univerzitet u Beogradu
URL: https://fedorabg.bg.ac.rs/fedora/get/o:14183/bdef:Content/get
► Medicina - Fizikalna medicina i rehabilitacija / Medicine - Physical medicine and rehabilitation
Uvod: Osteoartritis kuka najčešće dovodi uz ostale pridružene bolesti do generalno lošeg…
(more)
▼ Medicina - Fizikalna medicina i rehabilitacija /
Medicine - Physical medicine and rehabilitation
Uvod: Osteoartritis kuka najčešće dovodi uz ostale
pridružene bolesti do generalno lošeg zdravstvenog statusa osoba
gerijatrijske populacije. Krajnji stadijum osteoartritisa kuka se
uspešno tretira operativno, totalnom artroplastikom. Nakon totalne
artroplastike kuka sledstvena primena rehabilitacionih programa je
jedini izbor za obnovu mobilnosti i fizičke funkcionalnosti. Cilj:
Da se odredi efektivnost dodatog rehabilitacionog programa za
vežbanje ruku i gornjih partija tela na ishode rehabilitacije nakon
artroplastike kuka. Metod: Studija je dizajnirana kao prospektivna,
paralelna, randomizovana, kontrolna studija, sprovedena na
odeljenju ortopedije i rehabilitacije. U istraživanje je bilo
uključeno ukupno 70 pacijenata, starijih od 60 godina od ukupno
regrutovanih 98 nakon primenjenih kriterijuma isključivanja u
postoperativnoj rehabilitaciji nakon ugradnje totalne artroplastike
kuka. Učesnici interventne grupe su uzeli učešće u suplementarni
program vežbanja ruku i gornjih partija tela uz standardni
rehabilitcioni program, dok su učesnici kontrolne grupe imali samo
standardni rehabilitacioni program. Primarni ishod rehabilitacije
je procenjivan Harisovim upitnikom kojim su se merile promene u
fizičkim sposobnostima i u funkcionalnosti afektiranog kuka, a
sekundarnim ishodima su merene mišićna snaga preko snage stiska
šaka korišćenjem dinamometra kao i kvalitet života korišćenjem
opšeg upitnika o zdravlju SF-36. Rezultati: Interventna grupa je
pokazala signifikantno poboljšanje u odnosu na kontrolnu grupu u
fizičkim sposobnostima merenim Harisovim skorom nakon dve nedelje
(prosečna razlika = 4.7 boda) i nakon 12 nedelja (prosečna razlika
= 5.85 bodova). Takođe su učesnici interventne grupe pokazali
statistički veće poboljšanje nakon 12 nedelja: u boljoj mišićnoj
snazi merenoj stiskom obe šake (prosečna razlika dominantne šake
=4.16 i druge strane=2.8) i u domenu Fizička uloga SF-36 upitnika
(prosečna razlika=6.42 boda). Metodom linearne regresione analize
nakon prilagođavanja na sociodemografske i kliničke karakteristike
dodatni program vežbanja koji je praktikovala interventna grupa se
pokazao kao nezavisni prediktor za bolju fizičku fukcionalnost
(Harisov skor) nakon dve (b=4.593; p=0.018) i nakon 12 (b=3.324;
p=0.005) nedelja; bolju mišićnu snagu (stisak šaka) nakon 12
nedelja za dominantnu (b=1.258; p=0.007) i za nedominantnu šaku
(b=1.176; p=0.001), kao i za bolji kvalitet života povezanog sa
zdravljem SF 36 u sledećim domenima: Fizičko fukcionisanje nakon 2
nedelje (b=5.999; p=0.004), Fizička uloga nakon 12 nedelja
(b=6.909; p=0.040), Telesni bol nakon 12 nedelja (b=10.677;
p=0.002), i Mentalno zdravlje nakon 2 nedelje (b=9.562;
p=0.006)...
Advisors/Committee Members: Davidović, Mladen, 1946-.
Subjects/Keywords: Hip arthroplasty; rehabilitation; arm exercises;
elderly; quality of life; randomized trial
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APA ·
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CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Mitrović, Dragica N., 1. (2016). Delotvornost dodatnog kineziterapijskog programa za
funkcionalno vežbanje ruku na kvalitet života nakon operativnog
lečenja osteoartritisa kuka. (Thesis). Univerzitet u Beogradu. Retrieved from https://fedorabg.bg.ac.rs/fedora/get/o:14183/bdef:Content/get
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Mitrović, Dragica N., 1962-. “Delotvornost dodatnog kineziterapijskog programa za
funkcionalno vežbanje ruku na kvalitet života nakon operativnog
lečenja osteoartritisa kuka.” 2016. Thesis, Univerzitet u Beogradu. Accessed February 24, 2021.
https://fedorabg.bg.ac.rs/fedora/get/o:14183/bdef:Content/get.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Mitrović, Dragica N., 1962-. “Delotvornost dodatnog kineziterapijskog programa za
funkcionalno vežbanje ruku na kvalitet života nakon operativnog
lečenja osteoartritisa kuka.” 2016. Web. 24 Feb 2021.
Vancouver:
Mitrović, Dragica N. 1. Delotvornost dodatnog kineziterapijskog programa za
funkcionalno vežbanje ruku na kvalitet života nakon operativnog
lečenja osteoartritisa kuka. [Internet] [Thesis]. Univerzitet u Beogradu; 2016. [cited 2021 Feb 24].
Available from: https://fedorabg.bg.ac.rs/fedora/get/o:14183/bdef:Content/get.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Mitrović, Dragica N. 1. Delotvornost dodatnog kineziterapijskog programa za
funkcionalno vežbanje ruku na kvalitet života nakon operativnog
lečenja osteoartritisa kuka. [Thesis]. Univerzitet u Beogradu; 2016. Available from: https://fedorabg.bg.ac.rs/fedora/get/o:14183/bdef:Content/get
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Boston University
27.
Jang, Olivia.
Efficacy of two screen-based approaches to relieving preoperative anxiety in young children: preliminary data.
Degree: MS, Medical Sciences, 2017, Boston University
URL: http://hdl.handle.net/2144/23718
► BACKGROUND: Preoperative anxiety commonly occurs in young children prior to anesthesia induction. This anxiety is associated with poor post-operative outcomes such as increases in emergence…
(more)
▼ BACKGROUND: Preoperative anxiety commonly occurs in young children prior to anesthesia induction. This anxiety is associated with poor post-operative outcomes such as increases in emergence delirium occurrence and post-operative pain. Studies have demonstrated varying effectiveness of interventions such as clowns and video games used to engage and distract children from their anxiety. Anesthesiologists at Lucile Packard Children’s Hospital have designed a new screen-based modality, called the Bedside Entertainment Theatre (BERT), to distract children from their anxiety.
OBJECTIVE: The aim of this study is to examine the anxiety-relieving efficacy of BERT against a hand-held electronic tablet, another screen-based form of entertainment used to alleviate preoperative anxiety in children at the hospital.
METHODS: Children aged 4-10 undergoing non-emergent outpatient surgery at Lucile Packard Children’s Hospital and their primary caregiver were recruited for the study. Measures were taken at 5 timepoints from children, parents, and clinicians: in the preoperative holding area (T1), at entrance to the OR (T2), at induction (T3), after emergence from anesthesia (T4), and at a 1-week follow up (T5). Primary outcomes were preoperative anxiety, assessed by the modified Yale Preoperative Anxiety Scale (mYPAS) and Child Fear Scale (CFS), and induction compliance, assessed by the Induction Compliance Checklist (ICC). Secondary outcomes were emergence delirium, measured by the Pediatric Anesthesia Emergence Delirium Scale (PAED) and post-operative pain, measured by the Parents’ Post-operative Pain Measure (PPPM) and a Memory Recall Interview. Child covariates were temperament, measured by the Emotionality Activity Sociability Temperament Survey (EAS-TS) and the Children’s Behavior Questionnaire- Very Short Form (CBQ-VSF), and state-trait anxiety, measured by the Child State-Trait Anxiety Inventory (STAIC). Caregiver covariates were state-trait anxiety, measured by the State-Trait Anxiety Inventory (STAI) and caregiver pain catastrophizing about their child, measured by the Pain Catastrophizing Scale- Parent State (PCS-P State). This study is currently ongoing and plans to recruit 60 participants. Parent, child, and clinician satisfaction with usage of either intervention was also assessed.
RESULTS: There were no significant differences between mean preoperative anxiety scores of BERT and tablet users at all pre-induction timepoints. There was a significant increase in mean preoperative anxiety scores in BERT users from T1 to T2 and T1 to T3. There was also a significant increase in mean preoperative anxiety scores from T1 to T3 for tablet users. There were no other significant differences in primary and secondary outcomes between interventions. Only post-surgery PCS-P State scores for BERT users correlated with mYPAS scores at T3 (p < 0.05). No other measured covariates correlated with preoperative anxiety scores (p > 0.05).
CONCLUSIONS: Although preliminary results do not show differences between the interventions in…
Subjects/Keywords: Psychology; Audiovisual interventions; Child anxiety; Induction; Preoperative anxiety; Randomized trial
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APA ·
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MLA ·
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CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Jang, O. (2017). Efficacy of two screen-based approaches to relieving preoperative anxiety in young children: preliminary data. (Masters Thesis). Boston University. Retrieved from http://hdl.handle.net/2144/23718
Chicago Manual of Style (16th Edition):
Jang, Olivia. “Efficacy of two screen-based approaches to relieving preoperative anxiety in young children: preliminary data.” 2017. Masters Thesis, Boston University. Accessed February 24, 2021.
http://hdl.handle.net/2144/23718.
MLA Handbook (7th Edition):
Jang, Olivia. “Efficacy of two screen-based approaches to relieving preoperative anxiety in young children: preliminary data.” 2017. Web. 24 Feb 2021.
Vancouver:
Jang O. Efficacy of two screen-based approaches to relieving preoperative anxiety in young children: preliminary data. [Internet] [Masters thesis]. Boston University; 2017. [cited 2021 Feb 24].
Available from: http://hdl.handle.net/2144/23718.
Council of Science Editors:
Jang O. Efficacy of two screen-based approaches to relieving preoperative anxiety in young children: preliminary data. [Masters Thesis]. Boston University; 2017. Available from: http://hdl.handle.net/2144/23718
University of Colorado
28.
Davis, Kyle.
The Feasibility of Yoga in the Treatment of Antenatal Depression and Anxiety: A Pilot Study.
Degree: PhD, Psychology & Neuroscience, 2013, University of Colorado
URL: https://scholar.colorado.edu/psyc_gradetds/52
► BACKGROUND: The antenatal period is a sensitive time for both mother and the developing fetus. Antenatal depression affects approximately 15% of women and anxiety…
(more)
▼ BACKGROUND: The antenatal period is a sensitive time for both mother and the developing fetus. Antenatal depression affects approximately 15% of women and anxiety affects approximately 30%; moreover, the two are frequently comorbid, and studies suggest that they, singly and in combination, can have deleterious consequences for a woman as well as her family and infant. Although psychosocial and alternative treatments for antenatal depression and anxiety have not been studied extensively, they may provide a safe, acceptable, and efficacious option for antenatal women. Yoga interventions may be particularly well suited for depressed and anxious pregnant women given benefits associated with meditation and physical activity, two central components of yoga, and growing interest in yoga across the United States. METHODS: A
randomized controlled clinical
trial compared an eight-week yoga intervention to treatment as usual (TAU) among 46 pregnant women with symptoms of depression and/or anxiety recruited through health care providers and community advertisement. Participants were randomly assigned to the yoga or TAU condition and completed brief assessments weekly during the eight-week intervention and at post-intervention. RESULTS: Participants in the intervention group found yoga to be an acceptable intervention for anxiety and depression and reported high levels of satisfaction with the intervention. Pregnant women's reports of negative affect suggested significantly greater reductions among women who received yoga compared with TAU. Pregnant women receiving the yoga intervention also reported significantly lower anxiety and depression over time, but such changes were not significantly greater than those reported by women who received TAU. Analyses of secondary outcome measures suggest that prenatal yoga may increase self-efficacy and factors associated with positive self-regulation skills. CONCLUSION: Prenatal yoga was found to be a feasible and acceptable intervention for pregnant women with symptoms of anxiety and/or depression. Future research would benefit from more rigorous control conditions and larger sample sizes to gain a greater understanding of how yoga may affect antenatal depression and anxiety.
Advisors/Committee Members: Sona Dimidjian, Joanna Arch, Theresa D. Hernandez, Matt Jones, Cindy H. White.
Subjects/Keywords: Antenatal; Anxiety; Depression; Pregnancy; Randomized Controlled Trial; Yoga; Clinical Psychology
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APA (6th Edition):
Davis, K. (2013). The Feasibility of Yoga in the Treatment of Antenatal Depression and Anxiety: A Pilot Study. (Doctoral Dissertation). University of Colorado. Retrieved from https://scholar.colorado.edu/psyc_gradetds/52
Chicago Manual of Style (16th Edition):
Davis, Kyle. “The Feasibility of Yoga in the Treatment of Antenatal Depression and Anxiety: A Pilot Study.” 2013. Doctoral Dissertation, University of Colorado. Accessed February 24, 2021.
https://scholar.colorado.edu/psyc_gradetds/52.
MLA Handbook (7th Edition):
Davis, Kyle. “The Feasibility of Yoga in the Treatment of Antenatal Depression and Anxiety: A Pilot Study.” 2013. Web. 24 Feb 2021.
Vancouver:
Davis K. The Feasibility of Yoga in the Treatment of Antenatal Depression and Anxiety: A Pilot Study. [Internet] [Doctoral dissertation]. University of Colorado; 2013. [cited 2021 Feb 24].
Available from: https://scholar.colorado.edu/psyc_gradetds/52.
Council of Science Editors:
Davis K. The Feasibility of Yoga in the Treatment of Antenatal Depression and Anxiety: A Pilot Study. [Doctoral Dissertation]. University of Colorado; 2013. Available from: https://scholar.colorado.edu/psyc_gradetds/52
29.
Kivi, Marie.
Internet-based Treatment of Depression in Primary Care: Effectiveness and Feasibility.
Degree: 2015, University of Gothenburg / Göteborgs Universitet
URL: http://hdl.handle.net/2077/40675
► Internet-delivered psychological treatments emanate from a long tradition of psychological methods and should be seen as a natural effect of the evolution within psychology, society,…
(more)
▼ Internet-delivered psychological treatments emanate from a long tradition of psychological methods and should be seen as a natural effect of the evolution within psychology, society, and technology. Psychological treatments via Internet have been shown to be effective, however the vast majority of research has been conducted outside of health care, and corresponding research in primary care settings is sparse.
Psychological illness, such as depression, is common and most often treated within primary care, where therapist availability varies. One way to increase availability and provide effective and high quality psychological treatments could be to offer Internet-delivered therapy with minimal therapist support. This raises questions, however, such as: Is Internet treatment as effective as treatment as usual (TAU) in primary care? Which patients would benefit the most? And, is Internet treatment feasible within primary care?
This thesis reports findings from four studies based on the PRIM-NET project that implemented Internet-delivered cognitive behavior therapy (ICBT) at 16 primary care centers in the Västra Götaland region in Sweden. Patients thought to be suffering from mild-tomoderate depression were assessed. 90 patients were included and randomized to either ICBT or TAU.
Study I & II – Effectiveness: No significant differences in the reduction in depression
scores were found between the ICBT and TAU groups during treatment, after twelve
weeks of treatment (post) or at follow-up three and nine months after treatment. The
mean between-group effect size (Cohens’ d) was in effect zero, while there was a large
within-group effect size for both ICBT and TAU at post and at follow-ups.
Study III – Effectiveness and latent classes: Analysis of the ICBT patients’ depression trajectories by person-oriented methods corroborated the findings of an overall effect of the ICBT treatment. A large heterogeneity among the patients was also found. Three latent classes were identified: two classes (in total 50% of the patients) responding well to the treatment, while one class (50% of the patients) effectively did not respond. No distinguishing factors were identified for the non-responding class, but initial rapid response, or lack of response, as well as level of adherence to the ICBT, could give an indication of treatment outcome.
Study IV – Feasibility: Qualitative methods revealed the primary care therapists’ attitudes and experiences as positive; they viewed ICBT as an asset, would like to use ICBT programs in the future, and also introduce elements from ICBT into their face-to-face treatments. Some adaptations of the ICBT to better suit primary care circumstances were suggested.
Conclusion: Internet-delivered treatments seem to be both effective and feasible within
primary care and can be introduced as a complement to other treatments.
Subjects/Keywords: Internet; ICBT; Depression; Primary care; Randomized controlled trial; Person-oriented
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APA ·
Chicago ·
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APA (6th Edition):
Kivi, M. (2015). Internet-based Treatment of Depression in Primary Care: Effectiveness and Feasibility. (Thesis). University of Gothenburg / Göteborgs Universitet. Retrieved from http://hdl.handle.net/2077/40675
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Kivi, Marie. “Internet-based Treatment of Depression in Primary Care: Effectiveness and Feasibility.” 2015. Thesis, University of Gothenburg / Göteborgs Universitet. Accessed February 24, 2021.
http://hdl.handle.net/2077/40675.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Kivi, Marie. “Internet-based Treatment of Depression in Primary Care: Effectiveness and Feasibility.” 2015. Web. 24 Feb 2021.
Vancouver:
Kivi M. Internet-based Treatment of Depression in Primary Care: Effectiveness and Feasibility. [Internet] [Thesis]. University of Gothenburg / Göteborgs Universitet; 2015. [cited 2021 Feb 24].
Available from: http://hdl.handle.net/2077/40675.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Kivi M. Internet-based Treatment of Depression in Primary Care: Effectiveness and Feasibility. [Thesis]. University of Gothenburg / Göteborgs Universitet; 2015. Available from: http://hdl.handle.net/2077/40675
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
University of Gothenburg / Göteborgs Universitet
30.
Huseinovic, Ena.
From efficacy to effectiveness: Two randomized controlled trials of lifestyle intervention postpartum.
Degree: 2016, University of Gothenburg / Göteborgs Universitet
URL: http://hdl.handle.net/2077/44932
► The overall aim of this thesis was to evaluate if, and how, weight loss can be achieved in women with overweight and obesity after pregnancy…
(more)
▼ The overall aim of this thesis was to evaluate if, and how, weight loss can be achieved in women with overweight and obesity after pregnancy by combining results from two randomized controlled trials; LEVA and LEVA in Real Life. In the LEVA trial, a 12-wk diet intervention based on the Nordic Nutrition Recommendations produced a weight loss of 9%, which was sustained at 10% after 1 y, among 68 lactating women. However, important aspects of the dietary changes contributing to this weight loss remained to be examined. Therefore, in the first two papers, eating frequency and food choice in the LEVA trial are reported. In the following two papers, effectiveness of the diet treatment to produce weight loss among 110 postpartum women within a primary health care setting was examined through the LEVA in Real Life trial.
At baseline, LEVA women reported an eating frequency of 5.9 intake occasions/d (paper I). During the intervention, a positive association was found between change in eating frequency and change in energy intake. Also, women who received diet treatment reduced their eating frequency more during the intervention than did women not receiving it. Furthermore, results from paper II show that LEVA women had a high intake of sweets and salty snacks and an intake of fruit and vegetables below the recommendations at baseline. During the intervention, women receiving diet treatment reduced their intake of sweets, salty snacks and caloric drinks, and increased their intake of vegetables, more than did women not receiving it. At 1 y, only the difference in increased vegetable intake remained between the groups. Thus, findings from papers I and II suggest that dietary changes in line with current dietary guidelines can help women with overweight and obesity to achieve weight loss after pregnancy.
In the LEVA in Real Life trial, women randomized to the diet group achieved greater weight loss after 12 wk (6.7% vs 2.0%) and 1 y (11.6% vs 5.1%) compared to the control group (paper III). Preliminary data after 2 y show that the diet group has had a greater weight regain from 1-2 y compared to the control group such that the observed difference in weight loss at 1 y was not maintained at 2 y (7.5% vs 5.8%). In sum, the combined results from papers III and IV provide evidence that diet treatment delivered within a primary health care setting can produce clinically relevant weight loss among postpartum women with overweight and obesity. However, the results also highlight the difficulty of maintaining weight lost during the first year postpartum.
Subjects/Keywords: Diet intervention; Postpartum period; Weight loss; Randomized controlled trial
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Record Details
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APA ·
Chicago ·
MLA ·
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CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Huseinovic, E. (2016). From efficacy to effectiveness: Two randomized controlled trials of lifestyle intervention postpartum. (Thesis). University of Gothenburg / Göteborgs Universitet. Retrieved from http://hdl.handle.net/2077/44932
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Huseinovic, Ena. “From efficacy to effectiveness: Two randomized controlled trials of lifestyle intervention postpartum.” 2016. Thesis, University of Gothenburg / Göteborgs Universitet. Accessed February 24, 2021.
http://hdl.handle.net/2077/44932.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Huseinovic, Ena. “From efficacy to effectiveness: Two randomized controlled trials of lifestyle intervention postpartum.” 2016. Web. 24 Feb 2021.
Vancouver:
Huseinovic E. From efficacy to effectiveness: Two randomized controlled trials of lifestyle intervention postpartum. [Internet] [Thesis]. University of Gothenburg / Göteborgs Universitet; 2016. [cited 2021 Feb 24].
Available from: http://hdl.handle.net/2077/44932.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Huseinovic E. From efficacy to effectiveness: Two randomized controlled trials of lifestyle intervention postpartum. [Thesis]. University of Gothenburg / Göteborgs Universitet; 2016. Available from: http://hdl.handle.net/2077/44932
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
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Open Access Theses and Dissertations
