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University of Adelaide
1.
Newbury, Wendy Lynne.
Exploring the currency of spirometric predictive equations from the viewpoint of the lung age concept.
Degree: 2013, University of Adelaide
URL: http://hdl.handle.net/2440/83639 
► Spirometry is used to diagnose respiratory disease, to monitor disease progression and response to treatment, and in epidemiological surveys. As a large burden of disease…
(more)
▼ Spirometry is used to diagnose respiratory disease, to monitor disease progression and response to treatment, and in epidemiological surveys. As a large burden of disease is caused by cigarette smoking, spirometry has been incorporated in smoking cessation counselling in an attempt to improve quit rates. The concept of lung age (LA) was developed in 1985 in an effort to make spirometry results more easily understood by the lay person. Research results using LA to aid quitting remain inconclusive. This thesis investigates the need to update LA
equations, as
predictive equations based on old data may not be relevant for today’s populations, and contemporary
equations may result in a stronger message for smokers. New LA
equations were firstly developed using contemporary Australian data and four further LA
equations were derived from previously published FEV₁
predictive equations. A series of comparisons of LA
equations in contemporary Australian datasets followed. The first project compared the original Morris LA
equations with newly developed Australian LA
equations in an independent workplace dataset (males only). The second project compared four extra LA
equations derived from previously published FEV₁
equations from Europe, the United Kingdom, America and Australia with the Morris and the new Australian
equations. An independent dataset of randomly-selected males and females was used to compare these
equations with the Morris LA
equations and contemporary Australian LA
equations. Lastly, a different type of LA equation expressed as delta lung age (ΔLA), the difference between chronological age and lung age, based on the ratio of Forced Expiratory Volume in one second/Forced Vital Capacity (FEV₁/FVC), was compared with three other LA
equations based on FEV₁ alone. This project used three independent datasets (urban, rural and a workplace) for added strength. All LA
equations confirmed poorer lung function in smokers than in never smokers in all 3 independent datasets. LA estimates were approximately 20 years lower using the original Morris
equations when compared with the newest LA
equations. The differences seen between estimated LA using all six
equations were consistent in each analysis. The ΔLA equation gave extreme LA estimates in both the community-based datasets compared with the LA
equations based on FEV₁ alone. These results show that the Morris LA
equations need to be updated. However, there appears to be no advantage in using the ΔLA equation. The differences between the older and the newer LA
equations are most likely a result of cohort and period effects. This is also the case in the
predictive equations themselves. Continuously updating
predictive equations using recently acquired data will result in LA
equations that are more relevant to contemporary populations.
Advisors/Committee Members: Crockett, Alan Joseph (advisor), Ruffin, Richard Ernest (advisor), School of Population Health (school).
Subjects/Keywords: spirometry; lung age; predictive equations; smoking cessation; COPD; lung function
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APA (6th Edition):
Newbury, W. L. (2013). Exploring the currency of spirometric predictive equations from the viewpoint of the lung age concept. (Thesis). University of Adelaide. Retrieved from http://hdl.handle.net/2440/83639
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Newbury, Wendy Lynne. “Exploring the currency of spirometric predictive equations from the viewpoint of the lung age concept.” 2013. Thesis, University of Adelaide. Accessed February 27, 2021.
http://hdl.handle.net/2440/83639.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Newbury, Wendy Lynne. “Exploring the currency of spirometric predictive equations from the viewpoint of the lung age concept.” 2013. Web. 27 Feb 2021.
Vancouver:
Newbury WL. Exploring the currency of spirometric predictive equations from the viewpoint of the lung age concept. [Internet] [Thesis]. University of Adelaide; 2013. [cited 2021 Feb 27].
Available from: http://hdl.handle.net/2440/83639.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Newbury WL. Exploring the currency of spirometric predictive equations from the viewpoint of the lung age concept. [Thesis]. University of Adelaide; 2013. Available from: http://hdl.handle.net/2440/83639
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
University of Georgia
2.
Deveriya, Meera.
Consumer acceptability of aromatic and non-aromatic rice.
Degree: 2014, University of Georgia
URL: http://hdl.handle.net/10724/24129
► Rice is among the most important staple crops consumed worldwide. Segmentation of consumer acceptability of rice flavor can be used as a tool to improve…
(more)
▼ Rice is among the most important staple crops consumed worldwide. Segmentation of consumer acceptability of rice flavor can be used as a tool to improve consumer satisfaction. Consumer tests were conducted to determine differences in the
acceptability of aromatic and non-aromatic rice among different ethnicities. Consumer acceptability of rice was found to vary widely among different ethnicities and nationalities. Research directed towards improving rice flavor should highly be cognizant
of differences among nationalities when determining acceptability of rice samples. Combination of sensory descriptive analysis with consumer testing yielded predictive equations that helped to identify key descriptors contributing to acceptability.
Breeders can potentially use these specific characteristics to further enhance rice quality.
Subjects/Keywords: Consumer acceptability; Segmentation; Sensory descriptive Analysis; Predictive Equations; Flavor; Rice
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APA (6th Edition):
Deveriya, M. (2014). Consumer acceptability of aromatic and non-aromatic rice. (Thesis). University of Georgia. Retrieved from http://hdl.handle.net/10724/24129
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Deveriya, Meera. “Consumer acceptability of aromatic and non-aromatic rice.” 2014. Thesis, University of Georgia. Accessed February 27, 2021.
http://hdl.handle.net/10724/24129.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Deveriya, Meera. “Consumer acceptability of aromatic and non-aromatic rice.” 2014. Web. 27 Feb 2021.
Vancouver:
Deveriya M. Consumer acceptability of aromatic and non-aromatic rice. [Internet] [Thesis]. University of Georgia; 2014. [cited 2021 Feb 27].
Available from: http://hdl.handle.net/10724/24129.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Deveriya M. Consumer acceptability of aromatic and non-aromatic rice. [Thesis]. University of Georgia; 2014. Available from: http://hdl.handle.net/10724/24129
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
University of Melbourne
3.
Foo, Mathias Fui Lin.
Modelling and control design of river systems.
Degree: 2011, University of Melbourne
URL: http://hdl.handle.net/11343/37040
► Farming consumes a large amount of water usage and it is reported that large portion of this water is wasted through inefficient water distribution from…
(more)
▼ Farming consumes a large amount of water usage and it is reported that large portion of this water is wasted through inefficient water distribution from river to farms. More efficient water distribution and preservation of environmental demands can be achieved through better control and decision support systems. In order to design better control and decision support systems, a river model is required. This model needs to be able to capture the relevant river dynamics and easy to be used for control design.
Traditionally, the Saint Venant equations have been used to model river systems. These equations are nonlinear hyperbolic partial differential equation (PDE) and are solved numerically using Preissmann scheme. The simulated Saint Venant equations are compared against operational data from the Broken River, and it is found that the Saint Venant equations are accurate in representing the river systems. Through further study, it is found that a single segmentation, i.e. treating the river as one long stretch with uniform geometry is sufficiently accurate for representation of the river for the purpose of control design. For the representation of meandering river, the Saint Venant equations are as accurate a two-dimensional flow model. The nonlinearities in the Saint Venant equations are also investigated. From the nonlinearity test, it is found that the Saint Venant equations are approximately linear within an operating region.
The Saint Venant equations are difficult to use for control design. An alternative model is therefore sought. Based on the operational data from the Broken River, simple time delay model (TDM) and integrator delay model (IDM) are proposed and estimated using system identification procedures. These models are found to be accurate in capturing the relevant dynamics of the river system. Furthermore, they are easy to use for control design. It is found that the time delay varies with the flow and hence controllers must be robust to variations in the time delay. A comparison between both TDM and IDM and the Saint Venant equations shows that they are as accurate as the Saint Venant equations within the operating range. The TDM and IDM are desirable as they are easier to be used for control design and decision support system.
The TDM and IDM are used to design Model Predictive Control (MPC) to control the river system. The choice of using MPC is motivated by the fact that MPC handles constraints very well. Despite that, tuning the weights in the MPC cost function is not trivial. The methods of reverse engineering are used to obtain these weights. Building on the results of existing method of reverse engineering used in the literatures, two additional methods are developed. In addition, the design of MPC from scratch is also considered. A realistic year long simulations using both MPCs on the Broken River is carried out. The MPCs are compared with the current manual…
Subjects/Keywords: modelling; system identification; river systems; Saint Venant equations; control systems; model predictive control
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APA (6th Edition):
Foo, M. F. L. (2011). Modelling and control design of river systems. (Doctoral Dissertation). University of Melbourne. Retrieved from http://hdl.handle.net/11343/37040
Chicago Manual of Style (16th Edition):
Foo, Mathias Fui Lin. “Modelling and control design of river systems.” 2011. Doctoral Dissertation, University of Melbourne. Accessed February 27, 2021.
http://hdl.handle.net/11343/37040.
MLA Handbook (7th Edition):
Foo, Mathias Fui Lin. “Modelling and control design of river systems.” 2011. Web. 27 Feb 2021.
Vancouver:
Foo MFL. Modelling and control design of river systems. [Internet] [Doctoral dissertation]. University of Melbourne; 2011. [cited 2021 Feb 27].
Available from: http://hdl.handle.net/11343/37040.
Council of Science Editors:
Foo MFL. Modelling and control design of river systems. [Doctoral Dissertation]. University of Melbourne; 2011. Available from: http://hdl.handle.net/11343/37040
UCLA
4.
Lao, Liangfeng.
Economic Model Predictive Control: Handling Preventive Actuator and Sensor Maintenance and Application to Transport-Reaction Processes.
Degree: Chemical Engineering, 2015, UCLA
URL: http://www.escholarship.org/uc/item/8kj9t5p3
► In chemical process industries, maintenance costs may comprise of up to 20−30%of the operating budget, and therefore, improving maintenance practices can significantly impact plant economics…
(more)
▼ In chemical process industries, maintenance costs may comprise of up to 20−30%of the operating budget, and therefore, improving maintenance practices can significantly impact plant economics and reduce production losses. Developing so-called “Smart” preventive maintenance policies/systems of key manufacturing components, especially those that may cause process upsets, losses and downtime, is therefore an important task. A high percentage of the day-to-day preventive maintenance tasks in the chemical process industry deals with control actuators and measurement sensors employed by process control systems. Motivated by these considerations, the first part of this dissertation focuses on the development of methods for integrating the on-line preventive maintenance of actuators and sensors with advanced process control system design. To accomplish these preventive maintenance tasks, economic model predictive control (EMPC), that optimizes economic process performance over an operating horizon by employing a dynamic process model to predict the evolution of the process, is employed to maintain stable operation of a process while dictating an economically optimal operating policy with respect to varying numbers of control actuators and measurement sensors. Novel EMPC schemes are developed that explicitly account for scheduled preventive control actuator/sensor maintenance programs, process economics and feedback control. In the second part of this dissertation, EMPC of transport-reaction processes is considered for the first time. Compared with lumped-parameter processes, no work has been done on the problem of designing EMPC for transport-reaction processes modeled by partial differential equations (PDEs). The thesis proposes EMPC schemes those are formulated on the basis of suitable reduced-order models to ensure input and state constraint satisfaction and economics optimization for both parabolic and hyperbolic PDEs. Finally, the thesis concludes with the presentation of multiscale, computational fluid dynamics modeling framework for an industrial-level steam methane reforming unit.
Subjects/Keywords: Engineering; Chemical engineering; Computational Fluid Dynamics; Model Predictive Control; Partial Differential Equations; Preventive Maintenance; Steam Methane Reforming; Transport Reaction Processes
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APA (6th Edition):
Lao, L. (2015). Economic Model Predictive Control: Handling Preventive Actuator and Sensor Maintenance and Application to Transport-Reaction Processes. (Thesis). UCLA. Retrieved from http://www.escholarship.org/uc/item/8kj9t5p3
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Lao, Liangfeng. “Economic Model Predictive Control: Handling Preventive Actuator and Sensor Maintenance and Application to Transport-Reaction Processes.” 2015. Thesis, UCLA. Accessed February 27, 2021.
http://www.escholarship.org/uc/item/8kj9t5p3.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Lao, Liangfeng. “Economic Model Predictive Control: Handling Preventive Actuator and Sensor Maintenance and Application to Transport-Reaction Processes.” 2015. Web. 27 Feb 2021.
Vancouver:
Lao L. Economic Model Predictive Control: Handling Preventive Actuator and Sensor Maintenance and Application to Transport-Reaction Processes. [Internet] [Thesis]. UCLA; 2015. [cited 2021 Feb 27].
Available from: http://www.escholarship.org/uc/item/8kj9t5p3.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Lao L. Economic Model Predictive Control: Handling Preventive Actuator and Sensor Maintenance and Application to Transport-Reaction Processes. [Thesis]. UCLA; 2015. Available from: http://www.escholarship.org/uc/item/8kj9t5p3
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
5.
Jeeser Alves de Almeida.
Consumo máximo de oxigênio, validade de equações de predição e possível influência do polimorfismo I/D do gente da ECA sobre sua determinação.
Degree: 2011, Universidade Católica de Brasilia
URL: http://www.bdtd.ucb.br/tede/tde_busca/arquivo.php?codArquivo=1501
;
http://www.bdtd.ucb.br/tede/tde_busca/arquivo.php?codArquivo=1502
► Equações de predição têm sido amplamente utilizadas na determinação indireta do consumo máximo de oxigênio (VO2max), pois podem avaliar um grande número de pessoas com…
(more)
▼ Equações de predição têm sido amplamente utilizadas na determinação indireta do consumo máximo de oxigênio (VO2max), pois podem avaliar um grande número de pessoas com baixo custo e, na maioria das vezes, chegando próximo à especificidade de algumas modalidades esportivas. Contudo, sabendo-se que o VO2max pode ser influenciado por diversos fatores ambientais e genéticos, a validade destas equações em estimar o VO2max de brasileiros jovens deve ser melhor estudada. A presente dissertação integra dois estudos realizados com jovens estudantes fisicamente ativos. O objetivo do primeiro estudo foi analisar a validade da equação proposta por Cureton et al. (1995) em estimar o VO2max dos participantes a partir do teste de corrida de 1600m, além de sugerir e verificar a validade de uma nova equação de predição específica para brasileiros fisicamente ativos, a partir do desempenho no mesmo teste. O segundo estudo examinou a possível influência do polimorfismo I/D do gene da enzima conversora de angiotensina (ECA) sobre a determinação direta e indireta do VO2max nestes participantes. Foram recrutados, para o estudo I, trinta homens jovens e fisicamente ativos que realizaram um teste de corrida de 1600m e um teste incremental (TI) ergoespirométrico em esteira com análise de gases expirados para determinação direta do VO2max. Os participantes foram divididos em dois grupos (G1 e G2), sendo que no G1 a nova equação foi gerada (Regressão linear simples entre VO2max e velocidade média em 1600m 1600Vm) enquanto que a validade foi analisada no G2. Quando aplicada nos resultados do G2, ANOVA One Way revelou não haver diferença estatística entre o VO2max obtido pela equação de predição gerada no G1 [VO2max=(0,177*1600Vm) +8,101] com os valores do TI (50,1+7,2 mL.kg-1.min-1 vs 50,1+7,1 mL.kg-1.min-1), apresentando alta correlação entre si
(r=0,81). Entretanto, a equação de Cureton et al (1995) [VO2peak = -8,41(MRW) + 0,34 (MRW) 2 + 0,21 (Age x Gender) -0,84 (BMI) + 108,94] (44,2+6,5 mL.kg-1.min-1) mostrou-se diferente do TI bem como dos valores obtidos com a nova equação proposta (P<0,05). A análise de concordância entre os métodos foi analisada pela técnica de Bland & Altman. A partir desta nova equação, 57 participantes integraram o Estudo II e realizaram os mesmos procedimentos metodológicos, contudo tiveram seu DNA extraído e foram genotipados para o polimorfismo I/D do gene da ECA. Assim, os participantes foram separados em três grupos diferentes, de acordo com os genótipos do gene da ECA (DD ID II). Os resultados revelaram valores significativamente mais baixos de VO2max para indivíduos DD quando comparados com os indivíduos ID e II (45,6 +1,81 mL.kg-1.min-1) (51,9 +0,79 mL.kg-1.min-1) e54,4+0,96 mL.kg-1.min-1) respectivamente (P<0,01). Quando comparados o VO2max obtido no TI e o estimado pela equação gerada no Estudo I, para cada grupo específico, não foram observadas diferenças estatísticas intra-grupos. Portanto, a equação que foi gerada no Estudo I foi considerada válida para estimar o VO2max de indivíduos jovens fisicamente…
Advisors/Committee Members: Herbert Gustavo Simões.
Subjects/Keywords: polimorfismo (genética); enzima conversora da angiotensina; inibidores; teste de esforço; EDUCACAO FISICA; VO2max; predictive equations; ace gene; performance; EDUCACAO FISICA
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APA ·
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APA (6th Edition):
Almeida, J. A. d. (2011). Consumo máximo de oxigênio, validade de equações de predição e possível influência do polimorfismo I/D do gente da ECA sobre sua determinação. (Masters Thesis). Universidade Católica de Brasilia. Retrieved from http://www.bdtd.ucb.br/tede/tde_busca/arquivo.php?codArquivo=1501 ; http://www.bdtd.ucb.br/tede/tde_busca/arquivo.php?codArquivo=1502
Chicago Manual of Style (16th Edition):
Almeida, Jeeser Alves de. “Consumo máximo de oxigênio, validade de equações de predição e possível influência do polimorfismo I/D do gente da ECA sobre sua determinação.” 2011. Masters Thesis, Universidade Católica de Brasilia. Accessed February 27, 2021.
http://www.bdtd.ucb.br/tede/tde_busca/arquivo.php?codArquivo=1501 ; http://www.bdtd.ucb.br/tede/tde_busca/arquivo.php?codArquivo=1502.
MLA Handbook (7th Edition):
Almeida, Jeeser Alves de. “Consumo máximo de oxigênio, validade de equações de predição e possível influência do polimorfismo I/D do gente da ECA sobre sua determinação.” 2011. Web. 27 Feb 2021.
Vancouver:
Almeida JAd. Consumo máximo de oxigênio, validade de equações de predição e possível influência do polimorfismo I/D do gente da ECA sobre sua determinação. [Internet] [Masters thesis]. Universidade Católica de Brasilia; 2011. [cited 2021 Feb 27].
Available from: http://www.bdtd.ucb.br/tede/tde_busca/arquivo.php?codArquivo=1501 ; http://www.bdtd.ucb.br/tede/tde_busca/arquivo.php?codArquivo=1502.
Council of Science Editors:
Almeida JAd. Consumo máximo de oxigênio, validade de equações de predição e possível influência do polimorfismo I/D do gente da ECA sobre sua determinação. [Masters Thesis]. Universidade Católica de Brasilia; 2011. Available from: http://www.bdtd.ucb.br/tede/tde_busca/arquivo.php?codArquivo=1501 ; http://www.bdtd.ucb.br/tede/tde_busca/arquivo.php?codArquivo=1502
Colorado State University
6.
Parker, Thomas Richard.
Analysis of riprap design methods using predictive equations for maximum and average velocities at the tips of transverse in-stream structures.
Degree: MS(M.S.), Civil and Environmental Engineering, 2014, Colorado State University
URL: http://hdl.handle.net/10217/82478
► Transverse in-stream structures are used to enhance navigation, improve flood control, and reduce stream bank erosion. These structures are defined as elongated obstructions having one…
(more)
▼ Transverse in-stream structures are used to enhance navigation, improve flood control, and reduce stream bank erosion. These structures are defined as elongated obstructions having one end along the bank of a channel and the other projecting into the channel center and offer protection of erodible banks by deflecting flow from the bank to the channel center. Redirection of the flow moves erosive forces away from the bank, which enhances bank stability. The design, effectiveness, and performance of transverse in-stream structures have not been well documented, but recent efforts have begun to study the flow fields and profiles around and over transverse in-stream structures. It is essential for channel flow characteristics to be quantified and correlated to geometric structure parameters in order for proposed in-stream structure designs to perform effectively. Areas adjacent to the tips of in-stream transverse structures are particularly susceptible to strong approach flows, and an increase in shear stress can cause instability in the in-stream structure. As a result, the tips of the structures are a major focus in design and must be protected. Riprap size is a significant component of the design and stability of transverse in-stream structures, and guidance is needed to select the appropriate size such that the structure remains stable throughout its design life. The U.S. Bureau of Reclamation contracted the Engineering Research Center at Colorado State University to construct an undistorted 1:12 Froude scale, fixed bed, physical model of two channel bend geometries that are characteristic of a reach of the Rio Grande River south of the Cochiti Dam in central New Mexico. A series of factors including the construction of the Cochiti Dam and control levees has caused the historically braided river to meander and become more sinuous. Bank erosion threatens farmlands, irrigation systems, levee function, aquatic habitat, and riparian vegetation. The purpose of the model was to determine the effectiveness of in-stream structures in diffusing the magnitude of forces related to bank erosion. Multiple configurations of transverse in-stream structures with varying x, y, and z parameters were installed in the model, and velocity and shear stress data were collected. A series of twenty-two different configurations of transverse in-stream structures were tested. An analysis of the average and maximum velocities at the tips of the transverse in-stream structures was performed. Utilizing a channel bend approach velocity, average and maximum velocity ratios were calculated using physical model data. A set of dimensionless parameters consisting of influential structure design parameters was organized and arranged for regression analysis.
Predictive equations were developed that describe the ratios of maximum and average velocity at the tips of the in-stream structures to bend-averaged velocities. The
predictive equations for maximum and average velocity ratios function as a first approximation of in-stream structure riprap design…
Advisors/Committee Members: Thornton, Christopher (advisor), Abt, Steven (advisor), Williams, John (committee member).
Subjects/Keywords: tips of in-stream structures; in-stream structures; maximum velocity; predictive equations; riprap; riprap design methods
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APA (6th Edition):
Parker, T. R. (2014). Analysis of riprap design methods using predictive equations for maximum and average velocities at the tips of transverse in-stream structures. (Masters Thesis). Colorado State University. Retrieved from http://hdl.handle.net/10217/82478
Chicago Manual of Style (16th Edition):
Parker, Thomas Richard. “Analysis of riprap design methods using predictive equations for maximum and average velocities at the tips of transverse in-stream structures.” 2014. Masters Thesis, Colorado State University. Accessed February 27, 2021.
http://hdl.handle.net/10217/82478.
MLA Handbook (7th Edition):
Parker, Thomas Richard. “Analysis of riprap design methods using predictive equations for maximum and average velocities at the tips of transverse in-stream structures.” 2014. Web. 27 Feb 2021.
Vancouver:
Parker TR. Analysis of riprap design methods using predictive equations for maximum and average velocities at the tips of transverse in-stream structures. [Internet] [Masters thesis]. Colorado State University; 2014. [cited 2021 Feb 27].
Available from: http://hdl.handle.net/10217/82478.
Council of Science Editors:
Parker TR. Analysis of riprap design methods using predictive equations for maximum and average velocities at the tips of transverse in-stream structures. [Masters Thesis]. Colorado State University; 2014. Available from: http://hdl.handle.net/10217/82478
University of Adelaide
7.
Naser-ud-Din, Shazia.
Analysis and correlation study of human masseter muscle with EMG, ultrasonography & 3D imaging.
Degree: 2009, University of Adelaide
URL: http://hdl.handle.net/2440/63322
► Form and function are inextricably intertwined in orthodontics. Our understanding of the hard tissue relationship has been comprehensive, with extensive clinical trials both cross sectional…
(more)
▼ Form and function are inextricably intertwined in orthodontics. Our understanding of the hard tissue relationship has been comprehensive, with extensive clinical trials both cross sectional and longitudinal over the past several decades. The majority of studies have used standardized cephalograms that reflect our current concepts. However, the same cannot be stated for soft tissues and, more specifically, the muscles that envelope the skeletal bases.
The aim of the current study was to objectively evaluate the masseter muscle – one of the key elevator muscles in the human masticatory system with innovative diagnostic tools like electromyography (EMG), ultrasonography (US) and 3-D imaging (Mona Lisa®). Standard lateral cephalometrics were used as the gold standard for measuring the vertical facial dimensions and correlating the findings to the above mentioned modalities. This extensive study comprised three major components and involved subjects from the same cohort.
Firstly, the masseter muscle spindle reflexes were studied in dynamic chewing and the responses recorded with EMG in 28 human subjects. These were then analysed and correlated to the vertical facial proportion from standardized lateral cephalograms. Although substantial work has been done to evaluate the various trigeminal reflexes¹⁻³, limited research has investigated the reflexes from the muscle spindles in different facial proportions⁴. This is primarily due to the inherent complexity of the neurophysiology compounded by noise within the experimental models. Most often the method used to elicit a muscle spindle reflex in the human jaw involves a brief mechanical depression of the mandible, either by use of a tendon hammer or, if a more controlled stimulus is required, a computer-controlled stretching device⁵⁻⁷. In the current study, a sophisticated apparatus was utilized to deliver precise profile stimulus at predetermined intervals. Significant correlations were observed between the muscle spindle response and selected vertical proportions.
The second phase of study was to utilize US for measuring masseter muscle dimensions in the same cohort and once again correlate the various dimensions of the masseter muscle to the facial proportions generated by the lateral cephalometrics. US has been studied in dentistry for over four decades and it has been established as a safe, non-invasive, comfortable and cost-effective diagnostic implement. Also, US produces high resolution images of soft tissues more readily than MRI and CT scans⁸. Among the limitations for US there is the concern about
reproducibility and standardization particularly between operators. Hence, it is advisable to have a single operator for data collection in order to preclude interexaminer variability. Future use of US in dentistry will be favoured especially where
periodic evaluation is needed and there are concerns about radiation.
Finally, for a more holistic assessment, 3D optical scanning was used in the same sample cohort to analyse and correlate masseter muscle dimensions to…
Advisors/Committee Members: Sampson, Wayne John (advisor), Dreyer, Craig William (advisor), Turker, Kemal Sitki (advisor), School of Dentistry (school).
Subjects/Keywords: muscle spindles; periodontal mechanoreceptors (PMR); curvilinear measurements; predictive equations
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APA (6th Edition):
Naser-ud-Din, S. (2009). Analysis and correlation study of human masseter muscle with EMG, ultrasonography & 3D imaging. (Thesis). University of Adelaide. Retrieved from http://hdl.handle.net/2440/63322
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Naser-ud-Din, Shazia. “Analysis and correlation study of human masseter muscle with EMG, ultrasonography & 3D imaging.” 2009. Thesis, University of Adelaide. Accessed February 27, 2021.
http://hdl.handle.net/2440/63322.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Naser-ud-Din, Shazia. “Analysis and correlation study of human masseter muscle with EMG, ultrasonography & 3D imaging.” 2009. Web. 27 Feb 2021.
Vancouver:
Naser-ud-Din S. Analysis and correlation study of human masseter muscle with EMG, ultrasonography & 3D imaging. [Internet] [Thesis]. University of Adelaide; 2009. [cited 2021 Feb 27].
Available from: http://hdl.handle.net/2440/63322.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Naser-ud-Din S. Analysis and correlation study of human masseter muscle with EMG, ultrasonography & 3D imaging. [Thesis]. University of Adelaide; 2009. Available from: http://hdl.handle.net/2440/63322
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
University of Illinois – Chicago
8.
Sansone, Natasha D.
Mathematical Modeling as a Tool to Elucidate HCV Infection Kinetics and Treatment Response.
Degree: 2017, University of Illinois – Chicago
URL: http://hdl.handle.net/10027/22187
► Hepatitis C virus (HCV) treatment options have advanced significantly during the course of this thesis work, however, there are still approximately 170 million people chronically…
(more)
▼ Hepatitis C virus (HCV) treatment options have advanced significantly during the course of this thesis work, however, there are still approximately 170 million people chronically infected and our understanding of HCV infection dynamics and treatment response is still limited, restricting our ability to optimize the currently unaffordable treatment options, prevent re-infection of high risk individuals, and develop an effective vaccine. The underlying premise of this thesis is that by combining both experimental and modeling approaches we can achieve a more quantitative understanding of the viral lifecycle and develop mathematical tools to generate hypotheses and facilitate the investigations necessary to further our understanding of the system. While the modeling efforts in this thesis have utilized the HCV replicon system, the HCV cell culture (HCVcc) infection system, as well as kinetic data from chronically HCV-infected patients to yield quantitative estimates for drug efficacy and HCV infection parameters such as viral RNA stability/half-life, a focused goal of these combined approaches has been the development and refinement of the first data-driven multiscale model of HCV infection in vitro. The development and refinement of this model has been a process of discovery and is still not complete. Through the first iteration of our model we discovered that our understanding of chronic HCV infection was incomplete and obtained experimental evidence that supported the model prediction that non-productive HCV entry into infected cells plays a significant role in steady-state HCV dynamics. Subsequent analysis of the novel and multifunctional NS5a inhibitor, daclatasvir, revealed not only another important gap in our model regarding the specific infectivity of progeny virus produced, but also provided a plausible hypothesis regarding the new unexplained clinical phenomenon of patients who are positive for HCV RNA at the end of treatment, yet eventually achieve sustained virologic response (i.e. HCV cure) without additional treatment.
Advisors/Committee Members: Uprichard, Susan L (advisor), Lipton, Howard (committee member), Volz, Karl (committee member), He, Bin (committee member), Dahari, Harel (committee member), McLachlan, Alan (chair).
Subjects/Keywords: Virology; Kinetics; Viral Life Cycle; Mathematical Modeling; Predictive Models; Differential Equations; Pharmacokinetics; Drug Mechanism of Action; Direct Acting Antivirals
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APA (6th Edition):
Sansone, N. D. (2017). Mathematical Modeling as a Tool to Elucidate HCV Infection Kinetics and Treatment Response. (Thesis). University of Illinois – Chicago. Retrieved from http://hdl.handle.net/10027/22187
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Sansone, Natasha D. “Mathematical Modeling as a Tool to Elucidate HCV Infection Kinetics and Treatment Response.” 2017. Thesis, University of Illinois – Chicago. Accessed February 27, 2021.
http://hdl.handle.net/10027/22187.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Sansone, Natasha D. “Mathematical Modeling as a Tool to Elucidate HCV Infection Kinetics and Treatment Response.” 2017. Web. 27 Feb 2021.
Vancouver:
Sansone ND. Mathematical Modeling as a Tool to Elucidate HCV Infection Kinetics and Treatment Response. [Internet] [Thesis]. University of Illinois – Chicago; 2017. [cited 2021 Feb 27].
Available from: http://hdl.handle.net/10027/22187.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Sansone ND. Mathematical Modeling as a Tool to Elucidate HCV Infection Kinetics and Treatment Response. [Thesis]. University of Illinois – Chicago; 2017. Available from: http://hdl.handle.net/10027/22187
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
9.
Lima, Marcos Pereira.
Equações preditivas para determinar a temperatura interna do ar: envolventes em painel alveolar com cobertura verde.
Degree: Mestrado, Ciências da Engenharia Ambiental, 2009, University of São Paulo
URL: http://www.teses.usp.br/teses/disponiveis/18/18139/tde-03122009-160414/
;
► Introdução: Através da ferramenta estatística denominada análise de regressão linear múltipla se gerou equações preditivas de temperatura interna do ar de uma edificação com paredes…
(more)
▼ Introdução: Através da ferramenta estatística denominada análise de regressão linear múltipla se gerou equações preditivas de temperatura interna do ar de uma edificação com paredes e lajes compostas por painéis de concreto alveolar, com sistema de cobertura verde. Justificativa: Com equações preditivas é possível simular temperaturas internas de edificações utilizando uma pequena entrada de dados com uma precisão satisfatória. Utilizando tais equações é possível, também, corrigir erros de projetos antes de sua execução. Objetivos: Gerar equações preditivas para o período seco (outono e inverno) e para o período chuvoso (primavera e verão) para a edificação analisada. Metodologia: Foram selecionadas duas séries de dados, um referente ao período de característica seca e outro de característica chuvosa. Foram geradas equações preditivas de temperatura interna do ar máxima, média e mínima para os dois períodos, utilizando análise de regressão linear. Resultados: Foram geradas sete equações preditivas para o período seco e cinco para o período chuvoso. As diferenças máximas, em módulo, entre as temperaturas estimadas pelas equações e as monitoradas experimentalmente ficaram em aproximadamente 2°C. Conclusão: As equações preditivas geradas para os dois períodos considerados descrevem satisfatoriamente o comportamento térmico da edificação.
Introduction: Using a statistics tool called multiple linear regression, we created equations for predicting the indoor temperature in a building with walls and ceiling build from panels of alveolar concrete, with a green roof system. Explanation: Predictive equations enable simulations of indoor temperatures of buildings using a small number of data and with a satisfactory precision. They also allow corrections on project errors before they are put into effect. Objectives: Generate predictive equations for the building for the dry season (autumn and winter) and for the rainy season (spring and summer). Method: We selected two series of data, one for the dry and one for the rainy season. Using linear regression analysis we ran predictive equations for maximum, intermediate and minimum indoor temperatures of the air for both seasons. Results: We created seven predictive equations for the dry season and five for the wet season. The largest differences (in module) between the temperatures estimated using equations and monitored experimentally was approximately 2°C. Conclusion: The predictive equations generated for both periods described satisfactorily the thermal behavior of the building.
Advisors/Committee Members: Vecchia, Francisco Arthur da Silva.
Subjects/Keywords: Equações lineares; Equações preditivas de temperatura; Linear equations; Predições de temperaturas internas do ar; Predictions of indoor temperatures of the air; Predictive equations for the temperature
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APA ·
Chicago ·
MLA ·
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Manager
APA (6th Edition):
Lima, M. P. (2009). Equações preditivas para determinar a temperatura interna do ar: envolventes em painel alveolar com cobertura verde. (Masters Thesis). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/18/18139/tde-03122009-160414/ ;
Chicago Manual of Style (16th Edition):
Lima, Marcos Pereira. “Equações preditivas para determinar a temperatura interna do ar: envolventes em painel alveolar com cobertura verde.” 2009. Masters Thesis, University of São Paulo. Accessed February 27, 2021.
http://www.teses.usp.br/teses/disponiveis/18/18139/tde-03122009-160414/ ;.
MLA Handbook (7th Edition):
Lima, Marcos Pereira. “Equações preditivas para determinar a temperatura interna do ar: envolventes em painel alveolar com cobertura verde.” 2009. Web. 27 Feb 2021.
Vancouver:
Lima MP. Equações preditivas para determinar a temperatura interna do ar: envolventes em painel alveolar com cobertura verde. [Internet] [Masters thesis]. University of São Paulo; 2009. [cited 2021 Feb 27].
Available from: http://www.teses.usp.br/teses/disponiveis/18/18139/tde-03122009-160414/ ;.
Council of Science Editors:
Lima MP. Equações preditivas para determinar a temperatura interna do ar: envolventes em painel alveolar com cobertura verde. [Masters Thesis]. University of São Paulo; 2009. Available from: http://www.teses.usp.br/teses/disponiveis/18/18139/tde-03122009-160414/ ;
University of Oxford
10.
Wang, Hao.
Incremental sheet forming process : control and modelling.
Degree: PhD, 2014, University of Oxford
URL: http://ora.ox.ac.uk/objects/uuid:a80370f5-2287-4c6b-b7a4-44f06211564f
;
https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.618345
► Incremental Sheet Forming (ISF) is a progressive metal forming process, where the deformation occurs locally around the point of contact between a tool and the…
(more)
▼ Incremental Sheet Forming (ISF) is a progressive metal forming process, where the deformation occurs locally around the point of contact between a tool and the metal sheet. The final work-piece is formed cumulatively by the movements of the tool, which is usually attached to a CNC milling machine. The ISF process is dieless in nature and capable of producing different parts of geometries with a universal tool. The tooling cost of ISF can be as low as 5–10% compared to the conventional sheet metal forming processes. On the laboratory scale, the accuracy of the parts created by ISF is between ±1.5 mm and ±3mm. However, in order for ISF to be competitive with a stamping process, an accuracy of below ±1.0 mm and more realistically below ±0.2 mm would be needed. In this work, we first studied the ISF deformation process by a simplified phenomenal linear model and employed a predictive controller to obtain an optimised tool trajectory in the sense of minimising the geometrical deviations between the targeted shape and the shape made by the ISF process. The algorithm is implemented at a rig in Cambridge University and the experimental results demonstrate the ability of the model predictive controller (MPC) strategy. We can achieve the deviation errors around ±0.2 mm for a number of simple geometrical shapes with our controller. The limitations of the underlying linear model for a highly nonlinear problem lead us to study the ISF process by a physics based model. We use the elastoplastic constitutive relation to model the material law and the contact mechanics with Signorini’s type of boundary conditions to model the process, resulting in an infinite dimensional system described by a partial differential equation. We further developed the computational method to solve the proposed mathematical model by using an augmented Lagrangian method in function space and discretising by finite element method. The preliminary results demonstrate the possibility of using this model for optimal controller design.
Subjects/Keywords: 620.1; Engineering & allied sciences; Control engineering; Mechanical engineering; Mathematical modeling (engineering); Partial differential equations; Incremental sheet forming; model predictive control; computational mechanics; variational inequalities; finite element method
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APA ·
Chicago ·
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CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Wang, H. (2014). Incremental sheet forming process : control and modelling. (Doctoral Dissertation). University of Oxford. Retrieved from http://ora.ox.ac.uk/objects/uuid:a80370f5-2287-4c6b-b7a4-44f06211564f ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.618345
Chicago Manual of Style (16th Edition):
Wang, Hao. “Incremental sheet forming process : control and modelling.” 2014. Doctoral Dissertation, University of Oxford. Accessed February 27, 2021.
http://ora.ox.ac.uk/objects/uuid:a80370f5-2287-4c6b-b7a4-44f06211564f ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.618345.
MLA Handbook (7th Edition):
Wang, Hao. “Incremental sheet forming process : control and modelling.” 2014. Web. 27 Feb 2021.
Vancouver:
Wang H. Incremental sheet forming process : control and modelling. [Internet] [Doctoral dissertation]. University of Oxford; 2014. [cited 2021 Feb 27].
Available from: http://ora.ox.ac.uk/objects/uuid:a80370f5-2287-4c6b-b7a4-44f06211564f ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.618345.
Council of Science Editors:
Wang H. Incremental sheet forming process : control and modelling. [Doctoral Dissertation]. University of Oxford; 2014. Available from: http://ora.ox.ac.uk/objects/uuid:a80370f5-2287-4c6b-b7a4-44f06211564f ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.618345
Delft University of Technology
11.
Zhang, Z.
A theoretical basis for salinity intrusion in estuaries.
Degree: 2019, Delft University of Technology
URL: http://resolver.tudelft.nl/uuid:d95a29ff-8865-4484-864a-74fd75028292
;
urn:NBN:nl:ui:24-uuid:d95a29ff-8865-4484-864a-74fd75028292
;
d95a29ff-8865-4484-864a-74fd75028292
;
10.4233/uuid:d95a29ff-8865-4484-864a-74fd75028292
;
urn:NBN:nl:ui:24-uuid:d95a29ff-8865-4484-864a-74fd75028292
;
http://resolver.tudelft.nl/uuid:d95a29ff-8865-4484-864a-74fd75028292
► Saltwater intrusion is a crucial issue in estuaries. The spread of salinity is described by the dispersion coefficient. A purely empirical equation which links the…
(more)
▼ Saltwater intrusion is a crucial issue in estuaries. The spread of salinity is described by the dispersion coefficient. A purely empirical equation which links the effective tidal average dispersion to the freshwater discharge was developed by Van der Burgh [1972]. Combining it with the salt balance equation, Savenije [1986] derived a one-dimensional model for salinity intrusion in estuaries. This Van der Burgh model has performed surprisingly well around the world. However, the physical basis of the empirical Van der Burgh coefficient (퐾) is still weak. This study provides a theoretical basis for the Van der Burgh method and presents alternative
equations. MacCready [2004] presented a theoretical expression for the dispersion coefficient following a reductionist approach. Comparing the density-related parts of the
equations of the dispersion coefficient developed by Savenije and MacCready, a
predictive equation is obtained for the coefficient 퐾 using physical parameters. In addition, a new box-model has been developed considering the longitudinal densitydriven gravitational circulation and the lateral tide-driven horizontal circulation. The coefficient 퐾 (closely related to the Van der Burgh’s coefficient) is used as an index of the density-driven mixing mechanism while the tide-driven part is included by assuming that it is proportional to the longitudinal dispersion. This model is validated in sixteen alluvial estuaries worldwide by using calibrated 퐾 values (and the boundary conditions). These calibrated values correspond well with the predicted values from the theoretical derivation, revealing that 퐾 has smaller values when the tide is stronger. From a system perspective, alluvial estuaries are free to adjust dissipation processes to the energy sources that drive them. The potential energy of the river flow drives mixing by gravitational circulation. The maximum power concept assumes that the mixing takes place at the maximum power limit. To describe the complex mixing processes in estuaries holistically, different assumptions had to be made. The maximum power concept did not work satisfactorily when estuaries were assumed as isolated systems. However, by including the accelerating moment provided by the freshwater discharge, the open estuary system could be solved in analogy with Kleidon [2016] applying the maximum power concept. A new expression for the dispersion coefficient due to gravitational circulation has been derived and solved in combination with the advection-dispersion equation. This maximum power model works well in eighteen estuaries with a large convergence length, providing an alternative equation for the dispersion. These estuaries also have larger calibrated 퐾 values by the Van der Burgh method, revealing a relation between the empirical coefficient 퐾 and the geometry. All these models: the Van der Burgh model, the box-model, and the maximum power model, can describe the longitudinal salinity profiles. The comparison between these models implies that the empirical Van der Burgh coefficient is…
Advisors/Committee Members: Savenije, H.H.G., Wang, Z.B., Delft University of Technology.
Subjects/Keywords: Alluvial estuary; salinity intrusion; empirical model; predictive equations; maximum power concept
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APA ·
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Manager
APA (6th Edition):
Zhang, Z. (2019). A theoretical basis for salinity intrusion in estuaries. (Doctoral Dissertation). Delft University of Technology. Retrieved from http://resolver.tudelft.nl/uuid:d95a29ff-8865-4484-864a-74fd75028292 ; urn:NBN:nl:ui:24-uuid:d95a29ff-8865-4484-864a-74fd75028292 ; d95a29ff-8865-4484-864a-74fd75028292 ; 10.4233/uuid:d95a29ff-8865-4484-864a-74fd75028292 ; urn:NBN:nl:ui:24-uuid:d95a29ff-8865-4484-864a-74fd75028292 ; http://resolver.tudelft.nl/uuid:d95a29ff-8865-4484-864a-74fd75028292
Chicago Manual of Style (16th Edition):
Zhang, Z. “A theoretical basis for salinity intrusion in estuaries.” 2019. Doctoral Dissertation, Delft University of Technology. Accessed February 27, 2021.
http://resolver.tudelft.nl/uuid:d95a29ff-8865-4484-864a-74fd75028292 ; urn:NBN:nl:ui:24-uuid:d95a29ff-8865-4484-864a-74fd75028292 ; d95a29ff-8865-4484-864a-74fd75028292 ; 10.4233/uuid:d95a29ff-8865-4484-864a-74fd75028292 ; urn:NBN:nl:ui:24-uuid:d95a29ff-8865-4484-864a-74fd75028292 ; http://resolver.tudelft.nl/uuid:d95a29ff-8865-4484-864a-74fd75028292.
MLA Handbook (7th Edition):
Zhang, Z. “A theoretical basis for salinity intrusion in estuaries.” 2019. Web. 27 Feb 2021.
Vancouver:
Zhang Z. A theoretical basis for salinity intrusion in estuaries. [Internet] [Doctoral dissertation]. Delft University of Technology; 2019. [cited 2021 Feb 27].
Available from: http://resolver.tudelft.nl/uuid:d95a29ff-8865-4484-864a-74fd75028292 ; urn:NBN:nl:ui:24-uuid:d95a29ff-8865-4484-864a-74fd75028292 ; d95a29ff-8865-4484-864a-74fd75028292 ; 10.4233/uuid:d95a29ff-8865-4484-864a-74fd75028292 ; urn:NBN:nl:ui:24-uuid:d95a29ff-8865-4484-864a-74fd75028292 ; http://resolver.tudelft.nl/uuid:d95a29ff-8865-4484-864a-74fd75028292.
Council of Science Editors:
Zhang Z. A theoretical basis for salinity intrusion in estuaries. [Doctoral Dissertation]. Delft University of Technology; 2019. Available from: http://resolver.tudelft.nl/uuid:d95a29ff-8865-4484-864a-74fd75028292 ; urn:NBN:nl:ui:24-uuid:d95a29ff-8865-4484-864a-74fd75028292 ; d95a29ff-8865-4484-864a-74fd75028292 ; 10.4233/uuid:d95a29ff-8865-4484-864a-74fd75028292 ; urn:NBN:nl:ui:24-uuid:d95a29ff-8865-4484-864a-74fd75028292 ; http://resolver.tudelft.nl/uuid:d95a29ff-8865-4484-864a-74fd75028292
12.
Pereira, Luis Carlos Gomes.
Modélisation de l’hétérogénéité de la réponse cellulaire aux ligands pro-apoptotiques : Modeling cell response heterogeneity to pro-apoptotic ligands.
Degree: Docteur es, Informatique, 2019, Université Côte d'Azur (ComUE)
URL: http://www.theses.fr/2019AZUR4081
► L'apoptose est un processus physiologique essentiel permettant aux organismes de maintenir leurs tissus dans des conditions fonctionnelles. Lors du traitement du cancer, les mécanismes moléculaires…
(more)
▼ L'apoptose est un processus physiologique essentiel permettant aux organismes de maintenir leurs tissus dans des conditions fonctionnelles. Lors du traitement du cancer, les mécanismes moléculaires qui contrôlent la décision cellulaire d’engager ou d’éviter l’activation de cette voie sont mal connus, ce qui a un impact important sur le développement thérapeutique. Pour obtenir une vue globale du rôle des protéines impliquées dans la dynamique de la réponse cellulaire aux anticancéreux, une nouvelle description détaillée de la voie de l'apoptose au niveau du récepteur a été implémentée en un système d'équations différentielles ordinaires. Le modèle a été calibré sur des données expérimentale en cellule unique, de populations de cellules HeLa présentant une réponse hautement hétérogène au ligand, TRAIL. Les sensibilités des réactions apoptotiques dans notre modèle ont été évaluées en utilisant la diversité des comportements expérimentaux observés in vitro. Une série de tests et d'analyses informatiques ont été effectués avec notre modèle pour identifier les origines de l'hétérogénéité de la réponse cellulaire, faisant émerger de nouvelles caractéristiques de la voie apoptotique. Ces analyses apportent de nouvelles connaissances biologiques et soulignent l’importance de la régulation du complexe des récepteurs de la mort, éventuellement par la Caspase-10, comme le suggèrent de nouvelles découvertes expérimentales. Cette thèse offre une nouvelle approche pour découvrir des informations biologiques importantes en utilisant des données en cellule unique, de voies de signalisation à dynamiques hétérogènes.
Apoptosis is an essential physiological process through which organisms are able to equilibrate their cell numbers and maintain tissues in healthy and functional conditions. Despite the recent advances in the field, little is known on the molecular mechanisms controlling individual cell decisions to either engage or avoid the activation of this pathway upon cancer treatment, which inevitably impacts on therapeutics development. To obtain a global view of the intervening proteins and their role on cell response dynamics to anticancer drugs, a new and detailed description of the apoptosis pathway at the receptor level was translated into a system of ordinary differential equations. The model was calibrated to single-cell data, from recent experiments on a population of HeLa cells exhibiting a highly heterogeneous response when exposed to the death-inducing ligand TRAIL. The sensitivities of the apoptotic reactions in our model were evaluated using the diversity of experimental behaviors observed in vitro. A series of computational tests and analyses were performed with our model to identify the origins of cell response heterogeneity. New features of the apoptotic pathway emerged from a comparison of different heterogeneity modeling approaches, detecting a set of key reactions to be further expanded. These analyses yield new biological insights and highlights the importance of refining regulation of death receptor complex…
Advisors/Committee Members: Chaves, Madalena (thesis director), Roux, Jérémie (thesis director).
Subjects/Keywords: Apoptose extrinsèque; Equations différentielles d’action de masse; Décision de la mort cellulaire; Hétérogénéité; Distribution de paramètres; Régulation de la Caspase-8; Modèles prédictifs; Extrinsic apoptosis; Mass-action differential equations; Cell fate decision; Heterogeneity; Parameter distribution; Caspase-8 regulation; Predictive models
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Pereira, L. C. G. (2019). Modélisation de l’hétérogénéité de la réponse cellulaire aux ligands pro-apoptotiques : Modeling cell response heterogeneity to pro-apoptotic ligands. (Doctoral Dissertation). Université Côte d'Azur (ComUE). Retrieved from http://www.theses.fr/2019AZUR4081
Chicago Manual of Style (16th Edition):
Pereira, Luis Carlos Gomes. “Modélisation de l’hétérogénéité de la réponse cellulaire aux ligands pro-apoptotiques : Modeling cell response heterogeneity to pro-apoptotic ligands.” 2019. Doctoral Dissertation, Université Côte d'Azur (ComUE). Accessed February 27, 2021.
http://www.theses.fr/2019AZUR4081.
MLA Handbook (7th Edition):
Pereira, Luis Carlos Gomes. “Modélisation de l’hétérogénéité de la réponse cellulaire aux ligands pro-apoptotiques : Modeling cell response heterogeneity to pro-apoptotic ligands.” 2019. Web. 27 Feb 2021.
Vancouver:
Pereira LCG. Modélisation de l’hétérogénéité de la réponse cellulaire aux ligands pro-apoptotiques : Modeling cell response heterogeneity to pro-apoptotic ligands. [Internet] [Doctoral dissertation]. Université Côte d'Azur (ComUE); 2019. [cited 2021 Feb 27].
Available from: http://www.theses.fr/2019AZUR4081.
Council of Science Editors:
Pereira LCG. Modélisation de l’hétérogénéité de la réponse cellulaire aux ligands pro-apoptotiques : Modeling cell response heterogeneity to pro-apoptotic ligands. [Doctoral Dissertation]. Université Côte d'Azur (ComUE); 2019. Available from: http://www.theses.fr/2019AZUR4081
Université de Grenoble
13.
Pham, Van Thang.
Contributions à la commande prédictive des systèmes de lois de conservation : Contribution to predictive control for systems of conservation laws.
Degree: Docteur es, Sciences et technologie industrielles, 2012, Université de Grenoble
URL: http://www.theses.fr/2012GRENT051
► La Commande prédictive ou Commande Optimale à Horizon Glissant (COHG) devient de plus en plus populaire dans de nombreuses applications pratiques en raison de ses…
(more)
▼ La Commande prédictive ou Commande Optimale à Horizon Glissant (COHG) devient de plus en plus populaire dans de nombreuses applications pratiques en raison de ses avantages importants tels que la stabilisation et la prise en compte des contraintes. Elle a été bien étudiée pour des systèmes en dimension finie même dans le cas non linéaire. Cependant, son extension aux systèmes en dimension infinie n'a pas retenu beaucoup d'attention de la part des chercheurs. Ce travail de thèse apporte des contributions à l'application de cette approche aux systèmes de lois de conservation. Nous présentons tout d'abord une preuve de stabilité complète de la COHG pour certaines classes de systèmes en dimension infinie. Ce résultat est ensuite utilisé pour les systèmes hyperboliques 2x2 commandés aux frontières et appliqué à un problème de contrôle de canal d'irrigation. Nous proposons aussi l'extension de cette stratégie au cas de réseaux de systèmes hyperboliques 2x2 en cascade avec une application à un ensemble de canaux d'irrigation connectés. Nous étudions également les avantages de la COHG dans le contexte des systèmes non linéaires et semi-linéaires notamment vis-à-vis des chocs. Toutes les analyses théoriques sont validées par simulation afin d'illustrer l'efficacité de l'approche proposée.
The predictive control or Receding Horizon Optimal Control (RHOC) is becoming increasingly popular in many practical applications due to its significant advantages such as the stabilization and constraints handling. It has been well studied for finite dimensional systems even in the nonlinear case. However, its extension to infinite dimensional systems has not received much attention from researchers. This thesis proposes contributions on the application of this approach to systems of conservation laws. We present a complete proof of stability of RHOC for some classes of infinite dimensional systems. This result is then used for 2x2 hyperbolic systems with boundary control, and applied to an irrigation canal. We also propose the extension of this strategy to networks of cascaded 2x2 hyperbolic systems with an application to a set of connected irrigation canals. Furthermore, we study the benefits of RHOC in the context of nonlinear and semi-linear systems in particular with respect to the problem of shocks. All theoretical analyzes are validated by simulation in order to illustrate the effectiveness of the proposed approach.
Advisors/Committee Members: Georges, Didier (thesis director), Besançon, Gildas (thesis director).
Subjects/Keywords: Commande prédictive; Système de lois de conservation de l’adjoint; Système hyperbolique; Semi-groupe; Canal d'irrigation; Canalisation sous pression; Predictive control; Systems of conservation lawsthod; Hyperbolic systems; Semi-group; Open channel; Mots-clés de la thèse en anglais: Predictive control,Systems of conservation lawsthod,hyperbolic systems,semi-group,open channel,water-hammer equations
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APA (6th Edition):
Pham, V. T. (2012). Contributions à la commande prédictive des systèmes de lois de conservation : Contribution to predictive control for systems of conservation laws. (Doctoral Dissertation). Université de Grenoble. Retrieved from http://www.theses.fr/2012GRENT051
Chicago Manual of Style (16th Edition):
Pham, Van Thang. “Contributions à la commande prédictive des systèmes de lois de conservation : Contribution to predictive control for systems of conservation laws.” 2012. Doctoral Dissertation, Université de Grenoble. Accessed February 27, 2021.
http://www.theses.fr/2012GRENT051.
MLA Handbook (7th Edition):
Pham, Van Thang. “Contributions à la commande prédictive des systèmes de lois de conservation : Contribution to predictive control for systems of conservation laws.” 2012. Web. 27 Feb 2021.
Vancouver:
Pham VT. Contributions à la commande prédictive des systèmes de lois de conservation : Contribution to predictive control for systems of conservation laws. [Internet] [Doctoral dissertation]. Université de Grenoble; 2012. [cited 2021 Feb 27].
Available from: http://www.theses.fr/2012GRENT051.
Council of Science Editors:
Pham VT. Contributions à la commande prédictive des systèmes de lois de conservation : Contribution to predictive control for systems of conservation laws. [Doctoral Dissertation]. Université de Grenoble; 2012. Available from: http://www.theses.fr/2012GRENT051
Universidade do Estado do Rio de Janeiro
14.
José Silvio de Oliveira Barbosa.
Estudo comparativo de medidas de adiposidade pela absorciometria de dupla-emissão de raios X e pela antropometria.
Degree: PhD, 2016, Universidade do Estado do Rio de Janeiro
URL: http://www.bdtd.uerj.br/tde_busca/arquivo.php?codArquivo=10494
;
► O aumento da prevalência de sobrepeso/obesidade no mundo determinou o aumento de taxas de doenças crônicas não transmissíveis como diabetes mellitus, hipertensão arterial, doença coronariana,…
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▼ O aumento da prevalência de sobrepeso/obesidade no mundo determinou o aumento de taxas de doenças crônicas não transmissíveis como diabetes mellitus, hipertensão arterial, doença coronariana, entre outras. Como o aumento do tecido adiposo visceral (TAV) é mais importante do que o excesso de tecido adiposo, é necessário identificar formas de medir o TAV, para identificar pessoas sob maior risco de adoecimento. Como técnicas de medida de TAV de elevada precisão - ressonância nuclear magnética, tomografia computadoriza, absorciometria de dupla emissão de raios X (DXA) não estão disponíveis para grandes populações, nem para o cotidiano da clínica, é necessário o uso de outro recurso. As equações antropométricas de predição do TAV representam uma possibilidade, sendo necessária sua adequação à população estudada. O objetivo deste estudo foi o de identificar, através das variáveis antropométricas mensuradas no estudo Pró-Saúde, aquelas que melhor que refletem o acúmulo de gordura visceral mensurada pela DXA. Foi um estudo transversal, com parte de uma coorte de funcionários de uma universidade do Rio de Janeiro o Estudo Pró-Saúde (n=516; idade= 53 (11,0) anos), sendo 250 homens e 266 mulheres. Foram utilizadas duas estratégias para geração das equações: uma com base na correlação forte/muito forte de variáveis antropométricas com variáveis obtidas com o TAV medido pela DXA; outra considerou variáveis preenchendo critérios específicos. Os valores do índice de massa corporal (IMC) identificaram prevalência de sobrepeso/obesidade de 71,45% na amostra do Estudo Pró-Saúde, sendo estes valores mais elevados quando medidos pelo índice de massa gorda (79,4%). Foram geradas equações preditivas para toda a amostra, seguindo as duas estratégias, além de equações para homens e para mulheres. Também foram geradas equações preditivas para massa gorda de tronco em função do maior número de correlações com variáveis antropométricas que o TAV, e índice de massa gorda considerando que reflete melhor a adiposidade corporal do que o IMC, identificado pela maior prevalência de sobrepeso/obesidade quando comparada com a fornecida pelo IMC. Foi utilizada a análise gráfica de concordância de Bland-Altman para comparar os dados estimados pelas equações com os medidos pela DXA. A boa concordância entre os valores estimados e os observados referendou a utilização de equações de predição com base em variáveis antropométricas como uma ferramenta útil para uso na prática clínica na mensuração do tecido adiposo visceral, da massa gorda de tronco e do índice de massa gorda. Foi identificada uma variável pouco estudada até o momento, o índice de adiposidade central, como capaz de medir a adiposidade visceral, sendo necessário estudar sua adequação a outros grupos. Recomenda-se, para além do estudo, a adoção de rotina de divulgação dos dados relacionados à composição corporal em todas as densitometrias ósseas, como uma forma de aumentar o poder de diagnosticar precocemente modificações na distribuição da gordura corporal capazes de aumentar o risco de…
Advisors/Committee Members: Eduardo Faerstein, Mauro Felippe Felix Mediano, Vivian Wahrlich, Gustavo Casimiro Lopes, Cintia Chaves Curioni.
Subjects/Keywords: Tecido adiposo visceral; Equações antropométricas preditivas; Absorciometria de dupla emissão de raios-X; Prevenção de doenças crônicas; Visceral adipose tissue; Anthropometric predictive equations; Dual energy X-ray absorptiometry; Chronic diseases prevention; ANALISE NUTRICIONAL DE POPULACAO; Nutrição; Tecido adiposo; Equações antropométricas
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APA (6th Edition):
Barbosa, J. S. d. O. (2016). Estudo comparativo de medidas de adiposidade pela absorciometria de dupla-emissão de raios X e pela antropometria. (Doctoral Dissertation). Universidade do Estado do Rio de Janeiro. Retrieved from http://www.bdtd.uerj.br/tde_busca/arquivo.php?codArquivo=10494 ;
Chicago Manual of Style (16th Edition):
Barbosa, José Silvio de Oliveira. “Estudo comparativo de medidas de adiposidade pela absorciometria de dupla-emissão de raios X e pela antropometria.” 2016. Doctoral Dissertation, Universidade do Estado do Rio de Janeiro. Accessed February 27, 2021.
http://www.bdtd.uerj.br/tde_busca/arquivo.php?codArquivo=10494 ;.
MLA Handbook (7th Edition):
Barbosa, José Silvio de Oliveira. “Estudo comparativo de medidas de adiposidade pela absorciometria de dupla-emissão de raios X e pela antropometria.” 2016. Web. 27 Feb 2021.
Vancouver:
Barbosa JSdO. Estudo comparativo de medidas de adiposidade pela absorciometria de dupla-emissão de raios X e pela antropometria. [Internet] [Doctoral dissertation]. Universidade do Estado do Rio de Janeiro; 2016. [cited 2021 Feb 27].
Available from: http://www.bdtd.uerj.br/tde_busca/arquivo.php?codArquivo=10494 ;.
Council of Science Editors:
Barbosa JSdO. Estudo comparativo de medidas de adiposidade pela absorciometria de dupla-emissão de raios X e pela antropometria. [Doctoral Dissertation]. Universidade do Estado do Rio de Janeiro; 2016. Available from: http://www.bdtd.uerj.br/tde_busca/arquivo.php?codArquivo=10494 ;
Technical University of Lisbon
15.
Matias, Ana Catarina Francisco Nunes.
Hydrometry and body composition : methods development and validation in athletes.
Degree: 2014, Technical University of Lisbon
URL: http://www.rcaap.pt/detail.jsp?id=oai:www.repository.utl.pt:10400.5/6902
► Doutoramento em Motricidade Humana na especialidade de Atividade Física e Saúde
It is recognized that an accurate body composition and hydration assessment is relevant for…
(more)
▼ Doutoramento em Motricidade Humana na especialidade de Atividade Física e Saúde
It is recognized that an accurate body composition and hydration assessment is relevant for prescribing adequate training and nutritional regimens in highly trained athletes. The present dissertation presents four research studies conducted under the scope of the body composition and hydration methodological research area. An alternative solution to evaluate the extracellular water (ECW) compartment by the dilution techniques was validated to be used in highly trained athletes. Saliva was a valid biological fluid sample for ECW assessment in athletes using plasma as the reference fluid. Still under the methodological research area, two studies were conducted to test the validity of a bioelectrical impedance spectroscopy (BIS) in assessing body composition changes (fat mass and fat free mass) and water pools (total body water (TBW), ECW, and intracellular water (ICW)) of highly trained athletes. Using the 4-component model, BIS was accurate at a group level, but was of limited validity at an individual level for estimation of body composition changes from a weight stability period to prior a competition of national level judo athletes. Using dilution techniques as the reference methods for TBW and ECW by deuterium dilution using mass spectrometry and bromide dilution using high performance liquid chromatography, respectively, BIS was a valid tool in the assessment of TBW and its compartments in both male and female athletes. A last study was conducted to provide specific mathematical models for TBW, ECW, and ICW based on bioelectrical impedance analysis. The newly developed equations provide a valid alternative to evaluate hydric compartments and can be easily applied during training routines.
The aforementioned studies, contributed to improve the methodological research area of body composition and hydration assessment in the athletic population that ultimately will be determinant to improve athletes’ health and performance.
RESUMO: É reconhecida a relevância de uma avaliação válida da composição corporal para a prescrição adequada de programas de treino e dieta alimentar em atletas de alta competição. Esta dissertação apresenta quatro trabalhos de investigação conduzidos no âmbito da área metodológica da composição corporal e hidratação. Uma solução alternativa para avaliar a água extracelular (AEC), quando usadas as técnicas de diluição, foi validada para ser usada em atletas de alta competição. A saliva é uma amostra biológica confiável para a avaliação da AEC em atletas, tendo como referência o plasma. Ainda no domínio metodológico, dois estudos foram realizados para testar a validade da bioimpedância elétrica multiespectral (BIS) na avaliação das alterações da composição corporal (massa gorda e massa isenta de gordura) e dos compartimentos hídricos (água corporal total (ACT), AEC e água intracelular (AIC)) em atletas de alta competição. Tendo como referência o modelo a 4 compartimentos, a BIS apresentou-se como um método válido…
Advisors/Committee Members: Silva, Analiza Mónica Lopes de Almeida.
Subjects/Keywords: Athletes; Bioelectrical impedance analysis; Bioelectrical impedance spectroscopy; Body composition; Dilution techniques; Hydration; Multi-component models; Predictive equations; Season; Atletas; Bioimpedância elétrica multiespectral; Bioimpedância elétrica unifrequência; Composição corporal; Época desportiva; Hidratação; Modelos multi-compartimentais; Técnicas de diluição
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APA (6th Edition):
Matias, A. C. F. N. (2014). Hydrometry and body composition : methods development and validation in athletes. (Thesis). Technical University of Lisbon. Retrieved from http://www.rcaap.pt/detail.jsp?id=oai:www.repository.utl.pt:10400.5/6902
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Matias, Ana Catarina Francisco Nunes. “Hydrometry and body composition : methods development and validation in athletes.” 2014. Thesis, Technical University of Lisbon. Accessed February 27, 2021.
http://www.rcaap.pt/detail.jsp?id=oai:www.repository.utl.pt:10400.5/6902.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Matias, Ana Catarina Francisco Nunes. “Hydrometry and body composition : methods development and validation in athletes.” 2014. Web. 27 Feb 2021.
Vancouver:
Matias ACFN. Hydrometry and body composition : methods development and validation in athletes. [Internet] [Thesis]. Technical University of Lisbon; 2014. [cited 2021 Feb 27].
Available from: http://www.rcaap.pt/detail.jsp?id=oai:www.repository.utl.pt:10400.5/6902.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Matias ACFN. Hydrometry and body composition : methods development and validation in athletes. [Thesis]. Technical University of Lisbon; 2014. Available from: http://www.rcaap.pt/detail.jsp?id=oai:www.repository.utl.pt:10400.5/6902
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Louisiana State University
16.
Obulareddy, Sandeep.
Fundamental characterization of Louisiana HMA mixtures for the 2002 Mechanistic-Empirical Design Guide.
Degree: MSCE, Civil and Environmental Engineering, 2006, Louisiana State University
URL: etd-07142006-102431
;
https://digitalcommons.lsu.edu/gradschool_theses/3501
► The main objective of this research was to develop a catalog for dynamic modulus values inputs in the 2002 Empirical and Mechanistic Guide for Design…
(more)
▼ The main objective of this research was to develop a catalog for dynamic modulus values inputs in the 2002 Empirical and Mechanistic Guide for Design of New and Rehabilitated Pavement Structures (2002 M-E Design Guide) and to examine the permanent deformation characteristics of Louisiana hot mix asphalt (HMA) mixtures based on four laboratory tests, namely dynamic modulus |E*|, flow number, flow time and hamburg wheel tracker test. In addition, the sensitivity of rut prediction from the 2002 M-E Design Guide, using the dynamic modulus |E*| test results was evaluated and the Witczak and Hirsch models were also evaluated, for the prediction of dynamic modulus |E*| values for the mixtures considered. The dynamic modulus |E*| values, obtained from axial and indirect tension mode (IDT) mode of testing were also compared. Fifteen plant produced HMA mixtures designed for low, medium and high traffic levels were selected in this study. A catalog for dynamic modulus inputs in the 2002 Design Guide was developed for mixtures designed for low, medium and high traffic. Test results indicated that |E*| test results were sensitive to the nominal maximum aggregate size (NMAS) in HMA mixture. Larger aggregates combined with recycled asphalt (RAP) tended to have high |E*| values at high temperatures. The predicted rut depths from the 2002 M-E Design Guide followed similar trend as exhibited in the dynamic modulus |E*| test results at high temperatures. Both the Witczak and Hirsch models could predict the dynamic modulus |E*| values within a reasonable reliability. It was found that 73.3 percent of the dynamic modulus |E*| test results obtained from axial and indirect tension mode (IDT) were not statistically different.
Subjects/Keywords: flow time; flow number; hot mix asphalt; predictive equations; dynamic modulus; master curves; design guide
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APA (6th Edition):
Obulareddy, S. (2006). Fundamental characterization of Louisiana HMA mixtures for the 2002 Mechanistic-Empirical Design Guide. (Masters Thesis). Louisiana State University. Retrieved from etd-07142006-102431 ; https://digitalcommons.lsu.edu/gradschool_theses/3501
Chicago Manual of Style (16th Edition):
Obulareddy, Sandeep. “Fundamental characterization of Louisiana HMA mixtures for the 2002 Mechanistic-Empirical Design Guide.” 2006. Masters Thesis, Louisiana State University. Accessed February 27, 2021.
etd-07142006-102431 ; https://digitalcommons.lsu.edu/gradschool_theses/3501.
MLA Handbook (7th Edition):
Obulareddy, Sandeep. “Fundamental characterization of Louisiana HMA mixtures for the 2002 Mechanistic-Empirical Design Guide.” 2006. Web. 27 Feb 2021.
Vancouver:
Obulareddy S. Fundamental characterization of Louisiana HMA mixtures for the 2002 Mechanistic-Empirical Design Guide. [Internet] [Masters thesis]. Louisiana State University; 2006. [cited 2021 Feb 27].
Available from: etd-07142006-102431 ; https://digitalcommons.lsu.edu/gradschool_theses/3501.
Council of Science Editors:
Obulareddy S. Fundamental characterization of Louisiana HMA mixtures for the 2002 Mechanistic-Empirical Design Guide. [Masters Thesis]. Louisiana State University; 2006. Available from: etd-07142006-102431 ; https://digitalcommons.lsu.edu/gradschool_theses/3501
University of Guelph
17.
Smith, Emma.
Quantifying Health with Missing Data: Measuring the Impact of Fecal Microbiota Transplantation on Health-Related Quality of Life.
Degree: MS, Department of Mathematics and Statistics, 2017, University of Guelph
URL: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/10338
► Despite the proven clinical efficacy of fecal microbiota transplantation (FMT), there is limited information regarding its impact on health-related quality of life (HRQoL). Through employment…
(more)
▼ Despite the proven clinical efficacy of fecal microbiota transplantation (FMT), there is limited information regarding its impact on health-related quality of life (HRQoL). Through employment of the RAND 36-Item Health Survey (RAND-36), this thesis monitors the HRQoL of patients with recurrent and/or refractory Clostridium difficile infection (CDI) up to twelve weeks post- treatment. Multivariate imputation by chained
equations with
predictive mean matching is used to impute missing items and following examination of propensity scoring diagnostics, t-tests are used to investigate improvement in quality of life between follow-ups, as well as differences between the elderly and those under 65 years of age. Results suggest that FMT can positively influence the multidimensional health profile of patients with CDI as early as ten days post-FMT and reveal that despite suffering from impaired physical health, improvement occurs for the elderly at rates similar to their counterparts.
Advisors/Committee Members: Kim, Peter (advisor), Desmond, Tony (advisor).
Subjects/Keywords: C. difficile; quality of life; HRQoL; RAND 36-Item Health Survey; RAND-36; Clostridium difficile; fecal microbiota transplantation; FMT; imputation; missing data; Multivariate Imputation by Chained Equations; Predictive Mean Matching; MICE; PMM; propensity scores; elderly
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APA ·
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APA (6th Edition):
Smith, E. (2017). Quantifying Health with Missing Data: Measuring the Impact of Fecal Microbiota Transplantation on Health-Related Quality of Life. (Masters Thesis). University of Guelph. Retrieved from https://atrium.lib.uoguelph.ca/xmlui/handle/10214/10338
Chicago Manual of Style (16th Edition):
Smith, Emma. “Quantifying Health with Missing Data: Measuring the Impact of Fecal Microbiota Transplantation on Health-Related Quality of Life.” 2017. Masters Thesis, University of Guelph. Accessed February 27, 2021.
https://atrium.lib.uoguelph.ca/xmlui/handle/10214/10338.
MLA Handbook (7th Edition):
Smith, Emma. “Quantifying Health with Missing Data: Measuring the Impact of Fecal Microbiota Transplantation on Health-Related Quality of Life.” 2017. Web. 27 Feb 2021.
Vancouver:
Smith E. Quantifying Health with Missing Data: Measuring the Impact of Fecal Microbiota Transplantation on Health-Related Quality of Life. [Internet] [Masters thesis]. University of Guelph; 2017. [cited 2021 Feb 27].
Available from: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/10338.
Council of Science Editors:
Smith E. Quantifying Health with Missing Data: Measuring the Impact of Fecal Microbiota Transplantation on Health-Related Quality of Life. [Masters Thesis]. University of Guelph; 2017. Available from: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/10338
18.
Abboud, Candy.
Inférer et prédire les dynamiques d'espèces invasives : focus sur Xylella fastidiosa : Inferring and predicting invasive species dynamics : focus on Xylella fastidiosa.
Degree: Docteur es, Mathématiques appliquées, 2019, Aix Marseille Université
URL: http://www.theses.fr/2019AIXM0638
► La thèse porte sur la recherche d’une méthodologie générique permettant d'améliorer les prédictions d’une invasion biologique pour laquelle on ne dispose pas de modèle spécifique…
(more)
▼ La thèse porte sur la recherche d’une méthodologie générique permettant d'améliorer les prédictions d’une invasion biologique pour laquelle on ne dispose pas de modèle spécifique et dont les conditions initiales sont inconnues. Pour atteindre cet objectif, on procède suivant deux axes de recherche complémentaires. Dans le premier axe, on s’intéresse à l’inférence des invasions biologiques à partir d’un modèle spatio-temporel de propagation et de données collectées, en suivant une approche mécanistico-statistique. Elle repose sur (i) une équation aux dérivées partielles (EDP) offrant une représentation concise d’une dynamique qui envahit un domaine hétérogène, (ii) un modèle stochastique représentant le processus d’observation et (iii) une méthode d’inférence Bayésienne pour estimer les paramètres du modèle. Un modèle dérivé des processus de Markov déterministes par morceaux est proposé pour remplacer l'EDP permettant un compromis entre réalisme du modèle et facilité d’estimation. Dans le deuxième axe, on propose une approche prenant en compte les incertitudes entourant des modèles en compétition. La technique du Bayesian model-averaging combine les prédictions de ces modèles pour obtenir une prédiction unifiée améliorée. Cette technique a souvent été utilisée en sciences environnementales. Toutefois, elle n’est pas répandue dans le domaine de l’épidémiologie. L’un des buts méthodologiques de la thèse est d’en évaluer l’intérêt pour l’épidémiologie prédictive. Le cas d’étude est celui de Xylella fastidiosa, bactérie phytopathogène ayant le potentiel de causer en France une crise sanitaire majeure en santé végétale à l’image de celle qu’elle cause depuis 2013 en Italie
The thesis research aims to provide a generic methodology that improves the predictions of an invasive species dynamics for which no dedicated model is available and whose initial conditions are unknown. In order to achieve this goal, we proceed in two complementary lines of research. The first one is to propose a model&data-based inference method of biological invasions, in the framework of the so-called mechanistic-statistical approach. This method allows us to jointly estimate the introduction point and other parameters of the dynamics related to diffusion, reproduction and death. It is hinged on (i) a partial differential equation (PDE) that offers a concise description of the invasive species dynamics in a heterogeneous domain, (ii) a stochastic model that represents the observation process and (iii) a statistical Bayesian inference procedure for estimating model parameters. We propose to replace the PDE by a model issued from the framework of Piecewise-deterministic Markov Process to balance the trade-off between model realism and estimation easiness. The second research line consists on accounting for the uncertainty about models form using the Bayesian model-averaging. This method consists of combining predictions drawn from competing models in order to obtain a unique and ameliorated prediction. This technique is not widespread in the field…
Advisors/Committee Members: Soubeyrand, Samuel (thesis director), Parent, Éric (thesis director).
Subjects/Keywords: Approche Mecanistico-Statistique; Équations aux dérivées partielles; Inférence Bayesienne; Bayesian model-averaging; Épidémiologie prédictive; Invasions biologiques; Xylella fastidiosa; Mechanistic-Statistical approach; Partial differential equations; Bayesian inference; Bayesian model-Averaging; Predictive epidemiology; Biological invasions; Xylella fastidiosa
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APA ·
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APA (6th Edition):
Abboud, C. (2019). Inférer et prédire les dynamiques d'espèces invasives : focus sur Xylella fastidiosa : Inferring and predicting invasive species dynamics : focus on Xylella fastidiosa. (Doctoral Dissertation). Aix Marseille Université. Retrieved from http://www.theses.fr/2019AIXM0638
Chicago Manual of Style (16th Edition):
Abboud, Candy. “Inférer et prédire les dynamiques d'espèces invasives : focus sur Xylella fastidiosa : Inferring and predicting invasive species dynamics : focus on Xylella fastidiosa.” 2019. Doctoral Dissertation, Aix Marseille Université. Accessed February 27, 2021.
http://www.theses.fr/2019AIXM0638.
MLA Handbook (7th Edition):
Abboud, Candy. “Inférer et prédire les dynamiques d'espèces invasives : focus sur Xylella fastidiosa : Inferring and predicting invasive species dynamics : focus on Xylella fastidiosa.” 2019. Web. 27 Feb 2021.
Vancouver:
Abboud C. Inférer et prédire les dynamiques d'espèces invasives : focus sur Xylella fastidiosa : Inferring and predicting invasive species dynamics : focus on Xylella fastidiosa. [Internet] [Doctoral dissertation]. Aix Marseille Université 2019. [cited 2021 Feb 27].
Available from: http://www.theses.fr/2019AIXM0638.
Council of Science Editors:
Abboud C. Inférer et prédire les dynamiques d'espèces invasives : focus sur Xylella fastidiosa : Inferring and predicting invasive species dynamics : focus on Xylella fastidiosa. [Doctoral Dissertation]. Aix Marseille Université 2019. Available from: http://www.theses.fr/2019AIXM0638
19.
Segovia Castillo, Pablo.
Model-based control and diagnosis of inland navigation networks : Contrôle et diagnostic à base de modèle de réseaux de navigation intérieure.
Degree: Docteur es, Automatique, 2019, Ecole nationale supérieure Mines-Télécom Lille Douai; Universitat politécnica de Catalunya
URL: http://www.theses.fr/2019MTLD0003
► Cette thèse contribue à répondre au problème de la gestion optimale des ressources en eau dans les réseaux de navigation intérieure du point de vue…
(more)
▼ Cette thèse contribue à répondre au problème de la gestion optimale des ressources en eau dans les réseaux de navigation intérieure du point de vue de la théorie du contrôle. Les objectifs principales à atteindre consistent à garantir la navigabilité des réseaux de voies navigables, veiller à la réduction des coûts opérationnels et à la longue durée de vie des équipements. Lors de la conception de lois de contrôle, les caractéristiques des réseaux doivent être prises en compte, à savoir leurs dynamiques complexes, des retards variables et l’absence de pente. Afin de réaliser la gestion optimale, le contrôle efficace des structures hydrauliques doit être assuré. A cette fin, une approche de modélisation orientée contrôle est dérivée. Cependant, la formulation obtenue appartient à la classe des systèmes de descripteurs retardés, pour lesquels la commande prédictive MPC et l’estimation d’état sur horizon glissant MHE peuvent être facilement adaptés à cette formulation, tout en permettant de gérer les contraintes physiques et opérationnelles de manière naturelle. En raison de leur grande dimensionnalité, une mise en œuvre centralisée n’est souvent ni possible ni souhaitable. Compte tenu du fait que les réseaux de navigation intérieure sont des systèmes fortement couplés, une approche distribuée est proposée, incluant un protocole de communication entre agents. Malgré l’optimalité des solutions, toute erreur peut entraîner une gestion inefficace du système. Par conséquent, les dernières contributions de la thèse concernent la conception de stratégies de supervision permettant de détecter et d’isoler les pannes des équipements. Toutes les approches présentées sont appliquées à une étude de cas réaliste basée sur le réseau de voies navigables du nord e la France afin de valider leur efficacité.
This thesis addresses the problem of optimal management of water resources in inland navigation networks from a control theory perspective. The main objectives to be attained consist in guaranteeing the navigability condition of the network, minimizing the operational cost and ensuring a long lifespan of the equipment. However, their complex dynamics, large time delays and negligible bottom slopes complicate their management. In order to achieve the optimal management, the efficient control of the hydraulic structures must be ensured. To this end, a control-oriented modeling approach is derived. The resulting formulation belongs to the class of delayed desciptor systems, for which model predictive control and moving horizon estimation can be easily adapted, as well as being able to deal with physical and operational constraints in a natural manner. However, a centralized implementation is often neither possible nor desirable. As these networks are strongly coupled systems, a distributed approach is followed, featuring a communication protocol among agents. Despite the optimality of the solutions, any malfunction can lead to an inefficient system management. Therefore, the last part of the thesis regards the design of supervisory…
Advisors/Committee Members: Duviella, Eric (thesis director), Puig Cayuela, Vicenç (thesis director).
Subjects/Keywords: Réseaux de voies navigables; Systèmes à grande échelle; Systèmes à retard; Equations de Saint-Venant; Modélisation orientée contrôle; Commande prédictive; Estimation d'état sur horizon glissant; Partitionnement de systèmes; Commande et estimation d'état distribuées; Diagnostic de pannes; Inland navigation networks; Large-Scale systems; Time-Delay systems; Saint-Venant equations; Control-Oriented modeling; Model predictive control; Moving horizon estimation; Systems partitioning; Distributed control and state estimation; Fault diagnosis
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APA (6th Edition):
Segovia Castillo, P. (2019). Model-based control and diagnosis of inland navigation networks : Contrôle et diagnostic à base de modèle de réseaux de navigation intérieure. (Doctoral Dissertation). Ecole nationale supérieure Mines-Télécom Lille Douai; Universitat politécnica de Catalunya. Retrieved from http://www.theses.fr/2019MTLD0003
Chicago Manual of Style (16th Edition):
Segovia Castillo, Pablo. “Model-based control and diagnosis of inland navigation networks : Contrôle et diagnostic à base de modèle de réseaux de navigation intérieure.” 2019. Doctoral Dissertation, Ecole nationale supérieure Mines-Télécom Lille Douai; Universitat politécnica de Catalunya. Accessed February 27, 2021.
http://www.theses.fr/2019MTLD0003.
MLA Handbook (7th Edition):
Segovia Castillo, Pablo. “Model-based control and diagnosis of inland navigation networks : Contrôle et diagnostic à base de modèle de réseaux de navigation intérieure.” 2019. Web. 27 Feb 2021.
Vancouver:
Segovia Castillo P. Model-based control and diagnosis of inland navigation networks : Contrôle et diagnostic à base de modèle de réseaux de navigation intérieure. [Internet] [Doctoral dissertation]. Ecole nationale supérieure Mines-Télécom Lille Douai; Universitat politécnica de Catalunya; 2019. [cited 2021 Feb 27].
Available from: http://www.theses.fr/2019MTLD0003.
Council of Science Editors:
Segovia Castillo P. Model-based control and diagnosis of inland navigation networks : Contrôle et diagnostic à base de modèle de réseaux de navigation intérieure. [Doctoral Dissertation]. Ecole nationale supérieure Mines-Télécom Lille Douai; Universitat politécnica de Catalunya; 2019. Available from: http://www.theses.fr/2019MTLD0003
Universidade do Rio Grande do Norte
21.
Medeiros, Pedro Samuel Gomes.
Desenvolvimento e caracterização de soluções ternárias água-glicerol-propilenoglicol como fluido refrigerante secundário
.
Degree: 2012, Universidade do Rio Grande do Norte
URL: http://repositorio.ufrn.br/handle/123456789/15696
Subjects/Keywords: Refrigerante secundário alternativo. Termoacumulação. Propriedades termofísicas. Equações preditivas simplificadas. Glicerina do biodiesel;
Alternative secondary coolant. Thermal energy storage. Thermophysical properties. Simplified predictive equations. Glycerin from biodiesel
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APA (6th Edition):
Medeiros, P. S. G. (2012). Desenvolvimento e caracterização de soluções ternárias água-glicerol-propilenoglicol como fluido refrigerante secundário
. (Thesis). Universidade do Rio Grande do Norte. Retrieved from http://repositorio.ufrn.br/handle/123456789/15696
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Medeiros, Pedro Samuel Gomes. “Desenvolvimento e caracterização de soluções ternárias água-glicerol-propilenoglicol como fluido refrigerante secundário
.” 2012. Thesis, Universidade do Rio Grande do Norte. Accessed February 27, 2021.
http://repositorio.ufrn.br/handle/123456789/15696.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Medeiros, Pedro Samuel Gomes. “Desenvolvimento e caracterização de soluções ternárias água-glicerol-propilenoglicol como fluido refrigerante secundário
.” 2012. Web. 27 Feb 2021.
Vancouver:
Medeiros PSG. Desenvolvimento e caracterização de soluções ternárias água-glicerol-propilenoglicol como fluido refrigerante secundário
. [Internet] [Thesis]. Universidade do Rio Grande do Norte; 2012. [cited 2021 Feb 27].
Available from: http://repositorio.ufrn.br/handle/123456789/15696.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Medeiros PSG. Desenvolvimento e caracterização de soluções ternárias água-glicerol-propilenoglicol como fluido refrigerante secundário
. [Thesis]. Universidade do Rio Grande do Norte; 2012. Available from: http://repositorio.ufrn.br/handle/123456789/15696
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
22.
Afsi, Nawel.
Contrôle des procédés représentés par des équations aux dérivées partielles : Process control represented by partial differential equations.
Degree: Docteur es, Automatique, 2020, Lyon; École nationale d'Ingénieurs de Monastir (Tunisie)
URL: http://www.theses.fr/2020LYSE1033
► L’objectif de ce travail est le contrôle des procédés représentés par des équations aux dérivées partielles. Deux procédés ont été considérés. Le premier procédé est…
(more)
▼ L’objectif de ce travail est le contrôle des procédés représentés par des équations aux dérivées partielles. Deux procédés ont été considérés. Le premier procédé est un procédé de cristallisation en batch. L’objectif du contrôle est la génération d’une distribution des tailles de cristaux (DTC) ayant une taille moyenne adéquate. Tout d’abord, nous avons utilisé observateur à grand gain en cascade pour estimer cette taille moyenne en utilisant que la température du cristallisoir et la concentration du soluté. Ensuite, différents scénarios ont été testés afin de comparer les performances des différentes structures de la commande sans modèle. Le deuxième procédétraité est un procédé de polymérisation par ouverture de cycle du lactide. Cette réaction est très sensible aux impuretés. Alors, deux stratégies de contrôle ont été proposé afin de rétablir les conditions nominales en cas de dérive qui sont l’optimisation dynamique et la commande prédictive
This work aims to control the processes represented by partial differential equations. Two processes were considered. The first process is a batch crystallization process. The aim of the control is to generate a crystal size distribution (CSD) with an appropriate mean size. First, we used a high gain cascade observer to estimate this average size using only the crystallizer temperature and solute concentration. Then, different scenarios were tested to compare the performance of the different structures of the control system without a model. The second process treated is a lactide polymerization process. This reaction is very sensitive to impurities. So, two control strategies were proposed to restore the nominal conditions in case of drift, which are the dynamic optimization and predictive control
Advisors/Committee Members: Othman, Sami (thesis director), Sakly, Anis (thesis director), Bakir, Toufik (thesis director), Sheibat-Othman, Nida (thesis director).
Subjects/Keywords: Équations aux dérivées partielles (EDP); Cristallisation; Distribution des tailles de cristaux (DTC); Observateur à grand gain; Commande sans modèle; Polymérisation du lactide; Optimisation; Commande prédictive; Partial differential equations (PDE); High gain observer; Model-free control; Lactide polymerization; Model predictive control (MPC); Crystallization; Crystal size distribution (CSD); Optimization; 620
Record Details
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Record Details
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Afsi, N. (2020). Contrôle des procédés représentés par des équations aux dérivées partielles : Process control represented by partial differential equations. (Doctoral Dissertation). Lyon; École nationale d'Ingénieurs de Monastir (Tunisie). Retrieved from http://www.theses.fr/2020LYSE1033
Chicago Manual of Style (16th Edition):
Afsi, Nawel. “Contrôle des procédés représentés par des équations aux dérivées partielles : Process control represented by partial differential equations.” 2020. Doctoral Dissertation, Lyon; École nationale d'Ingénieurs de Monastir (Tunisie). Accessed February 27, 2021.
http://www.theses.fr/2020LYSE1033.
MLA Handbook (7th Edition):
Afsi, Nawel. “Contrôle des procédés représentés par des équations aux dérivées partielles : Process control represented by partial differential equations.” 2020. Web. 27 Feb 2021.
Vancouver:
Afsi N. Contrôle des procédés représentés par des équations aux dérivées partielles : Process control represented by partial differential equations. [Internet] [Doctoral dissertation]. Lyon; École nationale d'Ingénieurs de Monastir (Tunisie); 2020. [cited 2021 Feb 27].
Available from: http://www.theses.fr/2020LYSE1033.
Council of Science Editors:
Afsi N. Contrôle des procédés représentés par des équations aux dérivées partielles : Process control represented by partial differential equations. [Doctoral Dissertation]. Lyon; École nationale d'Ingénieurs de Monastir (Tunisie); 2020. Available from: http://www.theses.fr/2020LYSE1033
. 
Open Access Theses and Dissertations