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You searched for subject:(porous disc). Showing records 1 – 2 of 2 total matches.

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University of Wisconsin – Milwaukee

1. Guo, Ye. CAD-Based Porous Scaffold Design of Intervertebral Discs in Tissue Engineering.

Degree: PhD, Engineering, 2019, University of Wisconsin – Milwaukee

With the development and maturity of three-dimensional (3D) printing technology over the past decade, 3D printing has been widely investigated and applied in the field of tissue engineering to repair damaged tissues or organs, such as muscles, skin, and bones, Although a number of automated fabrication methods have been developed to create superior bio-scaffolds with specific surface properties and porosity, the major challenges still focus on how to fabricate 3D natural biodegradable scaffolds that have tailor properties such as intricate architecture, porosity, and interconnectivity in order to provide the needed structural integrity, strength, transport, and ideal microenvironment for cell- and tissue-growth. In this dissertation, a robust pipeline of fabricating bio-functional porous scaffolds of intervertebral discs based on different innovative porous design methodologies is illustrated. Firstly, a triply periodic minimal surface (TPMS) based parameterization method, which has overcome the integrity problem of traditional TPMS method, is presented in Chapter 3. Then, an implicit surface modeling (ISM) approach using tetrahedral implicit surface (TIS) is demonstrated and compared with the TPMS method in Chapter 4. In Chapter 5, we present an advanced porous design method with higher flexibility using anisotropic radial basis function (ARBF) and volumetric meshes. Based on all these advanced porous design methods, the 3D model of a bio-functional porous intervertebral disc scaffold can be easily designed and its physical model can also be manufactured through 3D printing. However, due to the unique shape of each intervertebral disc and the intricate topological relationship between the intervertebral discs and the spine, the accurate localization and segmentation of dysfunctional discs are regarded as another obstacle to fabricating porous 3D disc models. To that end, we discuss in Chapter 6 a segmentation technique of intervertebral discs from CT-scanned medical images by using deep convolutional neural networks. Additionally, some examples of applying different porous designs on the segmented intervertebral disc models are demonstrated in Chapter 6. Advisors/Committee Members: Zeyun Yu.

Subjects/Keywords: 3D Printing; Bio-scaffold; Porous Intervertebral Disc Design; Tissue Engineering; Computer Sciences; Electrical and Electronics

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APA (6th Edition):

Guo, Y. (2019). CAD-Based Porous Scaffold Design of Intervertebral Discs in Tissue Engineering. (Doctoral Dissertation). University of Wisconsin – Milwaukee. Retrieved from https://dc.uwm.edu/etd/2072

Chicago Manual of Style (16th Edition):

Guo, Ye. “CAD-Based Porous Scaffold Design of Intervertebral Discs in Tissue Engineering.” 2019. Doctoral Dissertation, University of Wisconsin – Milwaukee. Accessed September 19, 2020. https://dc.uwm.edu/etd/2072.

MLA Handbook (7th Edition):

Guo, Ye. “CAD-Based Porous Scaffold Design of Intervertebral Discs in Tissue Engineering.” 2019. Web. 19 Sep 2020.

Vancouver:

Guo Y. CAD-Based Porous Scaffold Design of Intervertebral Discs in Tissue Engineering. [Internet] [Doctoral dissertation]. University of Wisconsin – Milwaukee; 2019. [cited 2020 Sep 19]. Available from: https://dc.uwm.edu/etd/2072.

Council of Science Editors:

Guo Y. CAD-Based Porous Scaffold Design of Intervertebral Discs in Tissue Engineering. [Doctoral Dissertation]. University of Wisconsin – Milwaukee; 2019. Available from: https://dc.uwm.edu/etd/2072


Delft University of Technology

2. de Jonge, Maurits (author). Investigation of the Effect of Water Quality on Formation Damage using Porous Discs.

Degree: 2020, Delft University of Technology

Water injection is widely used in the petroleum industry for the increase of hydrocarbon recovery or disposal of wastewater. Water production and injection are the primary mechanisms in Geothermal Energy. Both include injecting water into a porous formation under matrix injection conditions. While maintaining water injection is vital in these branches in the industry, so is the occurrence of formation damage (FD) due to suspended contaminants or brine incompatibility. Suspended particles in injection water are retained or deposited due to the creation of an External Filter Cake (EFC) or Internal Filter Cake (IFC) impairing the permeability. Consequently, FD results in Water Injectivity Decline (WID). In most cases, the negative impact on injectivity translates into operational and economic targets not being met. WID, as a result of FD, is highly connected to the Water Quality (WQ) of the injection water. A new approach to water quality (WQ) testing is proposed which suffices as a bridging application of membrane filtration and core flooding. To establish a foundation for this method, tests are conducted by performing particle-laden suspension injection experiments with porous outcrop sandstone 8 mm thin discs utilizing the ‘Con-vergence Hydra’. An experimental study is conducted investigating the effect of water quality (WQ) on formation damage, using dilute (20-100 mg/l) Baracarb2 (CaCO3) particle suspension as a model contaminant. Baracarb2 is tested for particle size distribution, mineral content and stability within synthetic brine (resembling Seawater). Subsequently, suspension flow experiments are conducted on porous thin discs (Bentheimer & Berea sandstone) as well as membrane filters (MF0.45μm). As performing suspension injection test with porous thin disc test utilising the Hydra has not been done before, reproducibility of the experiments is tested. The reproducibility of performing experiments utilising the Hydra is high, with very little difference between the experimental outcomes.Varying WQ within each different porous media type illustrates remarkably similar trends. Moreover, it is demonstrated that by performing a similarity curve collapse, a master curve is obtained for each porous medium type which scales with suspension concentration for Baracarb2. The damage mechanisms explaining this master curve all demonstrate a linear permeability impairment in the early part of the experiments. Subsequently, a linear impedance trend is observed where it is assumed that cake filtration is dominant. The latter is demonstrated by calculating the Modified fouling Index (MFI), which shows a linear dependency with suspension concentration. SEM imaging and Micro-CT scan images substantiate the damage mechanisms hypothesized from the pressure and rate data.The Con-vergence Hydra utilising porous thin discs has great potential for on-site testing which allows fast and reliable results on permeability impairment, i.e. formation damage. Subsequently, monitoring of the water quality can be done by performing MFI… Advisors/Committee Members: Zitha, Pacelli (mentor), Voskov, Denis (mentor), Gebert, Julia (mentor), Welling, Marco (mentor), Delft University of Technology (degree granting institution).

Subjects/Keywords: Water quality; Formation damage; Con-vergence Hydra; Baracarb2; Calcium carbonate; Porous sandstone disc; MFI

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

de Jonge, M. (. (2020). Investigation of the Effect of Water Quality on Formation Damage using Porous Discs. (Masters Thesis). Delft University of Technology. Retrieved from http://resolver.tudelft.nl/uuid:a6b4ed98-a46c-4878-9cca-e97dbf753167

Chicago Manual of Style (16th Edition):

de Jonge, Maurits (author). “Investigation of the Effect of Water Quality on Formation Damage using Porous Discs.” 2020. Masters Thesis, Delft University of Technology. Accessed September 19, 2020. http://resolver.tudelft.nl/uuid:a6b4ed98-a46c-4878-9cca-e97dbf753167.

MLA Handbook (7th Edition):

de Jonge, Maurits (author). “Investigation of the Effect of Water Quality on Formation Damage using Porous Discs.” 2020. Web. 19 Sep 2020.

Vancouver:

de Jonge M(. Investigation of the Effect of Water Quality on Formation Damage using Porous Discs. [Internet] [Masters thesis]. Delft University of Technology; 2020. [cited 2020 Sep 19]. Available from: http://resolver.tudelft.nl/uuid:a6b4ed98-a46c-4878-9cca-e97dbf753167.

Council of Science Editors:

de Jonge M(. Investigation of the Effect of Water Quality on Formation Damage using Porous Discs. [Masters Thesis]. Delft University of Technology; 2020. Available from: http://resolver.tudelft.nl/uuid:a6b4ed98-a46c-4878-9cca-e97dbf753167

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