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You searched for subject:(persecutory ideation). Showing records 1 – 2 of 2 total matches.

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University of Michigan

1. Mueller, Savanna. Paranoid Ideation and Social Anxiety in Undergraduates and Clinical Populations.

Degree: PhD, Psychology, 2016, University of Michigan

Recent research suggests that paranoia, like other psychiatric symptoms, may exist on a continuum with normal experiences. What pushes people from the normal to the severe end of the continuum has yet to be determined. Theoretical models of paranoia place importance on negative emotion, especially social anxieties, and cognitive reasoning biases. To fully understand the differences in paranoid ideation in non-clinical and schizophrenia populations, more information is needed regarding the causal mechanisms. Experimental paradigms provide the mechanism to test potential pathways through which persecutory ideation can develop. The goal of this study is to reveal mechanisms that may contribute to increases in paranoid ideation by experimentally manipulating fear and by identifying other potential individual factors. A sample of 253 undergraduates was randomly assigned to a neutral or fearful experimental emotion induction. In both conditions, the presence of self-referential thoughts and persecutory ideation was assessed. Following the induction, participants completed ratings of self-referential and persecutory ideation and additional measures of social anxiety, general anxiety, depression and cognitive reasoning biases. These responses were compared to the level of self-referential and persecutory ideation in a sample of 46 individuals diagnosed with schizophrenia who completed self-report ratings of self-referential and persecutory ideation, general anxiety and depression but did not participate in the emotion induction. We found that the fear manipulation increased persecutory and self-referential thoughts in undergraduates. Further, social anxiety and cognitive reasoning biases were related to increases in persecutory ideation, such that the undergraduate group who were high in social anxiety or cognitive biases at baseline had paranoia at equivalent level as the schizophrenia group following emotion induction. This study provides evidence that ideas of reference and persecutory thoughts are not confined to individuals diagnosed with psychotic disorders as they can be enhanced by fear in individuals high on social anxiety and cognitive biases. Together, the results suggest that fearful states, cognitive biases and social anxiety are potential mechanisms for increases in paranoid thought. Advisors/Committee Members: Deldin, Patricia J (committee member), Himle, Joseph Alan (committee member), Lopez-Duran, Nestor L (committee member), Tso, Ivy (committee member).

Subjects/Keywords: paranoia; social anxiety; cognitive biases; persecutory ideation; Psychology; Social Sciences

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APA (6th Edition):

Mueller, S. (2016). Paranoid Ideation and Social Anxiety in Undergraduates and Clinical Populations. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/135866

Chicago Manual of Style (16th Edition):

Mueller, Savanna. “Paranoid Ideation and Social Anxiety in Undergraduates and Clinical Populations.” 2016. Doctoral Dissertation, University of Michigan. Accessed November 29, 2020. http://hdl.handle.net/2027.42/135866.

MLA Handbook (7th Edition):

Mueller, Savanna. “Paranoid Ideation and Social Anxiety in Undergraduates and Clinical Populations.” 2016. Web. 29 Nov 2020.

Vancouver:

Mueller S. Paranoid Ideation and Social Anxiety in Undergraduates and Clinical Populations. [Internet] [Doctoral dissertation]. University of Michigan; 2016. [cited 2020 Nov 29]. Available from: http://hdl.handle.net/2027.42/135866.

Council of Science Editors:

Mueller S. Paranoid Ideation and Social Anxiety in Undergraduates and Clinical Populations. [Doctoral Dissertation]. University of Michigan; 2016. Available from: http://hdl.handle.net/2027.42/135866


University of Minnesota

2. Wisner, Krista. An Investigation Into The Neural Nature Of Persecutory Ideation.

Degree: PhD, Psychology, 2016, University of Minnesota

Persecutory ideation is a common and distressing symptom that exists on a continuum with persecutory delusions. Although associated with severe negative consequences the neural mechanisms underlying persecutory ideation remain unclear. Contributing factors in this research deficit include i) low rates of studies specifically examining persecutory ideation, favoring instead broader symptom measurement, and ii) a lack of paradigms that sufficiently engage or examine specific mechanisms associated with the symptom. In this dissertation, a wide range of literature is reviewed to identify brain regions consistently associated with delusions or positive symptoms in order to aid development of a model of persecutory ideation and stimulate research. Brain regions highlighted by the review represented a convergence of neurobiological models of delusions, and were the focus of two empirical studies. In the first study we employed a novel economic social decision-making task in two samples during neuroimaging. We demonstrated a dorsal anterior cingulate and anterior insula (dACC-AI) network, a left frontal-parietal (lF-P) network, and a ventral medial orbital prefrontal (vmPFC/OFC) network were associated with distinct forms of distrust. We then revealed only the connectivity between the vmPFC/OFC and lF-P networks predicted persecutory ideation, suggesting a role of weakened top-down control on subjective valuation. Moreover, we established this mechanism was associated with unique environmental influence in community monozygotic twins. In our second study we aimed to replicate the task-based finding in two resting-state samples to demonstrate generalizability of the mechanism; however, confirmatory analyses did not replicate. In summary, the posited vmPFC/OFC - lF-P interconnectivity mechanism of persecutory ideation appears to be uniquely evoked by the economic social decision-making task. While this provides a novel perspective on persecutory ideation, replications in larger samples are needed.

Subjects/Keywords: decision-making; functional connectivity; monozygotic twins; persecutory ideation; schizophrenia; trust

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Wisner, K. (2016). An Investigation Into The Neural Nature Of Persecutory Ideation. (Doctoral Dissertation). University of Minnesota. Retrieved from http://hdl.handle.net/11299/202162

Chicago Manual of Style (16th Edition):

Wisner, Krista. “An Investigation Into The Neural Nature Of Persecutory Ideation.” 2016. Doctoral Dissertation, University of Minnesota. Accessed November 29, 2020. http://hdl.handle.net/11299/202162.

MLA Handbook (7th Edition):

Wisner, Krista. “An Investigation Into The Neural Nature Of Persecutory Ideation.” 2016. Web. 29 Nov 2020.

Vancouver:

Wisner K. An Investigation Into The Neural Nature Of Persecutory Ideation. [Internet] [Doctoral dissertation]. University of Minnesota; 2016. [cited 2020 Nov 29]. Available from: http://hdl.handle.net/11299/202162.

Council of Science Editors:

Wisner K. An Investigation Into The Neural Nature Of Persecutory Ideation. [Doctoral Dissertation]. University of Minnesota; 2016. Available from: http://hdl.handle.net/11299/202162

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