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University of Manchester

1. Palacios Gonzalez, Cesar. Human/Nonhuman Chimeras: Dignity, Organs, Gametes and Pregnancy.

Degree: 2016, University of Manchester

The question of whether within chimera research certain human/nonhuman animal chimeras should not be created has received significant attention in the philosophical community. In this thesis I examine, from a philosophical perspective, four questions related to this topic. These are: (i) Can ‘human’ dignity be invoked as an argument against the creation of human/nonhuman animal chimeras? (ii) Is it morally permissible to kill human/great-ape chimeras in order to solve the human organ shortage crisis? (iii) Is there something inherently wrong with creating human/nonhuman animal chimeras capable of human gamete production and human pregnancy? (iv) Can classic animal ethics issues concerning animal welfare throw light on the issue of killing human/pig chimeras for their human organs. These four questions, in turn, fall within what have been regarded as the three main problematic cases within chimera ethics: (1) the creation of human/nonhuman animal chimeras that could have brains predominantly constituted by human brain cells; (2) the creation of human/nonhuman animal chimeras that could look human-like; (3) the creation of human/nonhuman animal chimeras capable of human gamete production and human pregnancy. In the introduction I do four things. First, I define what chimeras are and point out some problems with some of the definitions that have been proposed. Secondly, I briefly investigate if there is a sound principled objection against the intentional creation of all intraspecific and interspecific chimeras. Thirdly, I present in a detailed fashion the four questions that this thesis poses in response. Finally, I explain how the four papers that are the main body of the thesis form a coherent body of work. In the fifth section of this thesis I present the abstracts of four papers. In the sixth section I make a comprehensive exploration of the dignity-based arguments that have been advanced against the creation of human/nonhuman animal chimeras that could possess human-like mental capacities, or that could possess certain cognitive capacities that we would not be able to properly classify. In the seventh section I examine the morality of killing human/great ape chimeras for their human organs. This paper is a detailed response to Shaw et al.’s (2014) ‘Using Non-Human Primates to Benefit Humans: Research and Organ Transplantation’. The eight section covers two topics. First I discuss the moral problems related to the creation of mainly nonhuman human/nonhuman animal chimeras capable of human gamete production. Secondly, I discuss the moral problems that would be generated by the fact that a sentient nonperson human/nonhuman animal chimera, that is predominantly nonhuman, was pregnant with a human conceptus. In the ninth section I further examine the chimera welfare issues that have emerged from assessing the morality of using human/pig chimeras as human organ sources. In the conclusion of the thesis I present a summary of the main points I have explored, and proceed to present how my dissertation adds to the academic… Advisors/Committee Members: CHAN, SARAH SW, Harris, John, Chan, Sarah.

Subjects/Keywords: chimeras; part-humans

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Palacios Gonzalez, C. (2016). Human/Nonhuman Chimeras: Dignity, Organs, Gametes and Pregnancy. (Doctoral Dissertation). University of Manchester. Retrieved from http://www.manchester.ac.uk/escholar/uk-ac-man-scw:300557

Chicago Manual of Style (16th Edition):

Palacios Gonzalez, Cesar. “Human/Nonhuman Chimeras: Dignity, Organs, Gametes and Pregnancy.” 2016. Doctoral Dissertation, University of Manchester. Accessed October 14, 2019. http://www.manchester.ac.uk/escholar/uk-ac-man-scw:300557.

MLA Handbook (7th Edition):

Palacios Gonzalez, Cesar. “Human/Nonhuman Chimeras: Dignity, Organs, Gametes and Pregnancy.” 2016. Web. 14 Oct 2019.

Vancouver:

Palacios Gonzalez C. Human/Nonhuman Chimeras: Dignity, Organs, Gametes and Pregnancy. [Internet] [Doctoral dissertation]. University of Manchester; 2016. [cited 2019 Oct 14]. Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:300557.

Council of Science Editors:

Palacios Gonzalez C. Human/Nonhuman Chimeras: Dignity, Organs, Gametes and Pregnancy. [Doctoral Dissertation]. University of Manchester; 2016. Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:300557


University of Manchester

2. Palacios González, César. Human/nonhuman chimeras : dignity, organs, gametes and pregnancy.

Degree: PhD, 2016, University of Manchester

The question of whether within chimera research certain human/nonhuman animal chimeras should not be created has received significant attention in the philosophical community. In this thesis I examine, from a philosophical perspective, four questions related to this topic. These are: (i) Can ‘human’ dignity be invoked as an argument against the creation of human/nonhuman animal chimeras? (ii) Is it morally permissible to kill human/great-ape chimeras in order to solve the human organ shortage crisis? (iii) Is there something inherently wrong with creating human/nonhuman animal chimeras capable of human gamete production and human pregnancy? (iv) Can classic animal ethics issues concerning animal welfare throw light on the issue of killing human/pig chimeras for their human organs. These four questions, in turn, fall within what have been regarded as the three main problematic cases within chimera ethics: (1) the creation of human/nonhuman animal chimeras that could have brains predominantly constituted by human brain cells; (2) the creation of human/nonhuman animal chimeras that could look human-like; (3) the creation of human/nonhuman animal chimeras capable of human gamete production and human pregnancy. In the introduction I do four things. First, I define what chimeras are and point out some problems with some of the definitions that have been proposed. Secondly, I briefly investigate if there is a sound principled objection against the intentional creation of all intraspecific and interspecific chimeras. Thirdly, I present in a detailed fashion the four questions that this thesis poses in response. Finally, I explain how the four papers that are the main body of the thesis form a coherent body of work. In the fifth section of this thesis I present the abstracts of four papers. In the sixth section I make a comprehensive exploration of the dignity-based arguments that have been advanced against the creation of human/nonhuman animal chimeras that could possess human-like mental capacities, or that could possess certain cognitive capacities that we would not be able to properly classify. In the seventh section I examine the morality of killing human/great ape chimeras for their human organs. This paper is a detailed response to Shaw et al.’s (2014) ‘Using Non-Human Primates to Benefit Humans: Research and Organ Transplantation’. The eight section covers two topics. First I discuss the moral problems related to the creation of mainly nonhuman human/nonhuman animal chimeras capable of human gamete production. Secondly, I discuss the moral problems that would be generated by the fact that a sentient nonperson human/nonhuman animal chimera, that is predominantly nonhuman, was pregnant with a human conceptus. In the ninth section I further examine the chimera welfare issues that have emerged from assessing the morality of using human/pig chimeras as human organ sources. In the conclusion of the thesis I present a summary of the main points I have explored, and proceed to present how my dissertation adds to the academic…

Subjects/Keywords: 576.5; chimeras; part-humans

Record DetailsSimilar RecordsGoogle PlusoneFacebookTwitterCiteULikeMendeleyreddit

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Palacios González, C. (2016). Human/nonhuman chimeras : dignity, organs, gametes and pregnancy. (Doctoral Dissertation). University of Manchester. Retrieved from https://www.research.manchester.ac.uk/portal/en/theses/humannonhuman-chimeras-dignity-organs-gametes-and-pregnancy(5dcf3b56-6cc5-46fd-81a6-643a77c7e09f).html ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.694262

Chicago Manual of Style (16th Edition):

Palacios González, César. “Human/nonhuman chimeras : dignity, organs, gametes and pregnancy.” 2016. Doctoral Dissertation, University of Manchester. Accessed October 14, 2019. https://www.research.manchester.ac.uk/portal/en/theses/humannonhuman-chimeras-dignity-organs-gametes-and-pregnancy(5dcf3b56-6cc5-46fd-81a6-643a77c7e09f).html ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.694262.

MLA Handbook (7th Edition):

Palacios González, César. “Human/nonhuman chimeras : dignity, organs, gametes and pregnancy.” 2016. Web. 14 Oct 2019.

Vancouver:

Palacios González C. Human/nonhuman chimeras : dignity, organs, gametes and pregnancy. [Internet] [Doctoral dissertation]. University of Manchester; 2016. [cited 2019 Oct 14]. Available from: https://www.research.manchester.ac.uk/portal/en/theses/humannonhuman-chimeras-dignity-organs-gametes-and-pregnancy(5dcf3b56-6cc5-46fd-81a6-643a77c7e09f).html ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.694262.

Council of Science Editors:

Palacios González C. Human/nonhuman chimeras : dignity, organs, gametes and pregnancy. [Doctoral Dissertation]. University of Manchester; 2016. Available from: https://www.research.manchester.ac.uk/portal/en/theses/humannonhuman-chimeras-dignity-organs-gametes-and-pregnancy(5dcf3b56-6cc5-46fd-81a6-643a77c7e09f).html ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.694262

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