You searched for subject:(optical coherence technology).
Showing records 1 – 7 of
7 total matches.
No search limiters apply to these results.
Columbia University
1.
Singh-Moon, Rajinder.
Design and development of optical reflectance spectroscopy and optical coherence tomography catheters for myocardial tissue characterization.
Degree: 2019, Columbia University
URL: https://doi.org/10.7916/d8-5jzn-1g66 
► Catheter ablation therapy attempts to restore sinus rhythm in arrhythmia patients by producing site-specific tissue modification along regions which cause abnormal electrical activity. This treatment,…
(more)
▼ Catheter ablation therapy attempts to restore sinus rhythm in arrhythmia patients by producing site-specific tissue modification along regions which cause abnormal electrical activity. This treatment, though widely used, often requires repeat procedures to observe long-term therapeutic benefits. This limitation is driven in part by challenges faced by conventional schemes in validating lesion adequacy at the time of the procedure. Optical techniques are well-suited for the interrogation and characterization of biological tissues. In particular, optical coherence tomography (OCT) relies on coherence gating of singly-scattered light to enable high-resolution structural imaging for tissue diagnostics and procedural guidance. Alternatively, optical reflectance spectroscopy (ORS) is a point measurement technique which makes use of incoherent, multiply-scattered light to probe tissue volumes and derive important data from its optical signature. ORS relies on the fact that light-tissue interactions are regulated by absorption and scattering, which directly relate to the intrinsic tissue biochemistry and cellular organization. In this thesis, we explore the integration of these modalities into ablation catheters for obtaining procedural metrics which could be utilized to guide catheter ablation therapy. We first present the development of an accelerated computational light transport model and its application for guiding ORS catheter design. A custom ORS-integrated ablation catheter is then implemented and tested within porcine specimens in vitro. A model is proposed for real-time estimation of lesion size based on changes in spectral morphology acquired during ablation. We then fabricated custom integrated OCT M-mode RF catheters and present a model for detecting contact status based on deep convolutional neural networks trained on endomyocardial images. Additionally, we demonstrate for the first time, tracking of RF-induced lesion formation employing OCT Doppler micro-velocimetry; this response is shown to be commensurate with the degree of treatment. We further demonstrate for the first time spectroscopic tracking of kinetics related to the heme oxidation cascade during thermal treatment, which are linked to tissue denaturation. The pairing of these modalities into a single RF catheter was also validated for guiding lesion delivery in vitro and within live pigs. Finally, we conclude with a proof-of-concept demonstration of ORS as a mapping tool to guide epicardial ablation in human donor hearts. These results showcase the vast potential of ORS and OCT empowered RF catheters for aiding intraprocedural guidance of catheter ablation procedures which could be utilized alongside current practices.
Subjects/Keywords: Electrical engineering; Biomedical engineering; Medical technology; Optical coherence tomography; Reflectance spectroscopy; Catheters
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Singh-Moon, R. (2019). Design and development of optical reflectance spectroscopy and optical coherence tomography catheters for myocardial tissue characterization. (Doctoral Dissertation). Columbia University. Retrieved from https://doi.org/10.7916/d8-5jzn-1g66
Chicago Manual of Style (16th Edition):
Singh-Moon, Rajinder. “Design and development of optical reflectance spectroscopy and optical coherence tomography catheters for myocardial tissue characterization.” 2019. Doctoral Dissertation, Columbia University. Accessed April 13, 2021.
https://doi.org/10.7916/d8-5jzn-1g66.
MLA Handbook (7th Edition):
Singh-Moon, Rajinder. “Design and development of optical reflectance spectroscopy and optical coherence tomography catheters for myocardial tissue characterization.” 2019. Web. 13 Apr 2021.
Vancouver:
Singh-Moon R. Design and development of optical reflectance spectroscopy and optical coherence tomography catheters for myocardial tissue characterization. [Internet] [Doctoral dissertation]. Columbia University; 2019. [cited 2021 Apr 13].
Available from: https://doi.org/10.7916/d8-5jzn-1g66.
Council of Science Editors:
Singh-Moon R. Design and development of optical reflectance spectroscopy and optical coherence tomography catheters for myocardial tissue characterization. [Doctoral Dissertation]. Columbia University; 2019. Available from: https://doi.org/10.7916/d8-5jzn-1g66
2.
Wang, Zhao.
Intravascular Optical Coherence Tomography Image
Analysis.
Degree: PhD, Biomedical Engineering, 2013, Case Western Reserve University School of Graduate Studies
URL: http://rave.ohiolink.edu/etdc/view?acc_num=case1364673682
► Coronary artery disease (CAD) is the leading cause of death in the world. Most acute coronary events such as heart attacks and sudden deaths are…
(more)
▼ Coronary artery disease (CAD) is the leading cause of
death in the world. Most acute coronary events such as heart
attacks and sudden deaths are due to the rupture of atherosclerotic
plaques inside the arteries. Intravascular
Optical Coherence
Tomography (IVOCT), a high resolution (10-20µm) imaging modality
that performs cross-sectional imaging of coronary arteries by
measuring echoes of backscattered light, is rapidly becoming a
promising imaging modality for diagnosis of CAD. Compared to
alternative technologies such as intravascular ultrasound (IVUS),
IVOCT with better resolution allows characterization of
atherosclerotic plaques and evaluation of coronary stenting with
unprecendented details. Currently, analysis of OCT images has been
typically conducted manually in an extremely time-consuming manner.
The aim of this PhD dissertation is to develop advanced image
processing algorithms and software to automate the task and thereby
reduce the image analysis time drastically.In this dissertation, we
developed image analysis algorithms for a variety of IVOCT
applications, including: (1) 3-D lumen boundary segmentation, (2)
Guide wire artifact segmentation, (3) Automated calibration of
IVOCT images, (4) Volumetric quantification of fibrous caps, (5)
Automated segmentation of calcified plaques, (6) Automated
quantification of macrophages and (7) Automated stent analysis,
covering almost all the essential tasks performed in the
Cardiovascular Imaging Core Laboratories (Core Lab). The algorithms
we have developed have been extensively validated using a large
number of data sets, and are robust to be used for real world
clinical data analysis. Furthermore, we developed the prototype
software OCTivat (intravascular OCT image visualization and
analysis toolkit) for IVOCT image visualization and analysis, and
it is being used by the interventional cardiologists in the Core
Lab at the University Hospitals Case Medical Center. These image
analysis methods, as well as OCTivat, can reduce the IVOCT image
analysis time from tens of hours down to minutes. This may enable
large clinical trial analysis and real-time feedback during
clinical procedures, and may potentially improve patient
care.
Advisors/Committee Members: Rollins, Andrew (Advisor).
Subjects/Keywords: Biomedical Engineering; Optics; Information Technology; coronary artery disease; optical coherence tomography; image analysis; image processing; atherosclerotic plaques; stents
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Wang, Z. (2013). Intravascular Optical Coherence Tomography Image
Analysis. (Doctoral Dissertation). Case Western Reserve University School of Graduate Studies. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=case1364673682
Chicago Manual of Style (16th Edition):
Wang, Zhao. “Intravascular Optical Coherence Tomography Image
Analysis.” 2013. Doctoral Dissertation, Case Western Reserve University School of Graduate Studies. Accessed April 13, 2021.
http://rave.ohiolink.edu/etdc/view?acc_num=case1364673682.
MLA Handbook (7th Edition):
Wang, Zhao. “Intravascular Optical Coherence Tomography Image
Analysis.” 2013. Web. 13 Apr 2021.
Vancouver:
Wang Z. Intravascular Optical Coherence Tomography Image
Analysis. [Internet] [Doctoral dissertation]. Case Western Reserve University School of Graduate Studies; 2013. [cited 2021 Apr 13].
Available from: http://rave.ohiolink.edu/etdc/view?acc_num=case1364673682.
Council of Science Editors:
Wang Z. Intravascular Optical Coherence Tomography Image
Analysis. [Doctoral Dissertation]. Case Western Reserve University School of Graduate Studies; 2013. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=case1364673682
Universidade Nova
3.
Almeida, Mariana Quelhas Dias Rodrigues.
Detection of purkinje images for automatic positioning of fixation target and interferometric measurements of anterior eye chamber.
Degree: 2015, Universidade Nova
URL: http://www.rcaap.pt/detail.jsp?id=oai:run.unl.pt:10362/15787
► In cataract surgery, the eye’s natural lens is removed because it has gone opaque and doesn’t allow clear vision any longer. To maintain the eye’s…
(more)
▼ In cataract surgery, the eye’s natural lens is removed because it has gone opaque and doesn’t allow clear vision any longer. To maintain the eye’s
optical power, a new artificial lens must be inserted. Called Intraocular Lens (IOL), it needs to be modelled in order to have the correct refractive power to substitute the natural lens.
Calculating the refractive power of this substitution lens requires precise anterior eye chamber measurements. An interferometry equipment, the AC Master from Zeiss Meditec, AG, was in use for half a year to perform these measurements. A Low
Coherence Interferometry (LCI) measurement beam is aligned with the eye’s
optical axis, for precise measurements of anterior eye chamber distances. The eye follows a fixation target in order to make the visual axis align with the
optical axis. Performance problems occurred, however, at this step. Therefore, there was a necessity to develop a new procedure that ensures better alignment between the eye’s visual and
optical axes, allowing a more user friendly and versatile procedure, and eventually automatizing the whole process.
With this instrument, the alignment between the eye’s
optical and visual axes is detected when Purkinje reflections I and III are overlapped, as the eye follows a fixation target.
In this project, image analysis is used to detect these Purkinje reflections’ positions, eventually automatically detecting when they overlap.
Automatic detection of the third Purkinje reflection of an eye following a fixation target
is possible with some restrictions. Each pair of detected third Purkinje reflections is used in automatically calculating an acceptable starting position for the fixation target, required for precise measurements of anterior eye chamber distances.
Advisors/Committee Members: Leitgeb, Rainer, Grajciar, Branislav.
Subjects/Keywords: Fixation target; Image analysis; Eye’s optical and visual axis; Low Coherence Interferometry (LCI); Purkinje reflections; (Eye length) IOL measurements; Domínio/Área Científica::Engenharia e Tecnologia::Engenharia Médica
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Almeida, M. Q. D. R. (2015). Detection of purkinje images for automatic positioning of fixation target and interferometric measurements of anterior eye chamber. (Thesis). Universidade Nova. Retrieved from http://www.rcaap.pt/detail.jsp?id=oai:run.unl.pt:10362/15787
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Almeida, Mariana Quelhas Dias Rodrigues. “Detection of purkinje images for automatic positioning of fixation target and interferometric measurements of anterior eye chamber.” 2015. Thesis, Universidade Nova. Accessed April 13, 2021.
http://www.rcaap.pt/detail.jsp?id=oai:run.unl.pt:10362/15787.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Almeida, Mariana Quelhas Dias Rodrigues. “Detection of purkinje images for automatic positioning of fixation target and interferometric measurements of anterior eye chamber.” 2015. Web. 13 Apr 2021.
Vancouver:
Almeida MQDR. Detection of purkinje images for automatic positioning of fixation target and interferometric measurements of anterior eye chamber. [Internet] [Thesis]. Universidade Nova; 2015. [cited 2021 Apr 13].
Available from: http://www.rcaap.pt/detail.jsp?id=oai:run.unl.pt:10362/15787.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Almeida MQDR. Detection of purkinje images for automatic positioning of fixation target and interferometric measurements of anterior eye chamber. [Thesis]. Universidade Nova; 2015. Available from: http://www.rcaap.pt/detail.jsp?id=oai:run.unl.pt:10362/15787
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
University of Edinburgh
4.
Kufcsák, András.
Spectrally and temporally resolved single photon counting in advanced biophotonics applications.
Degree: PhD, 2020, University of Edinburgh
URL: http://hdl.handle.net/1842/36964
► Biomedicine requires highly sensitive and efficient light sensors to analyse light-tissue or light-sample interactions. Single-photon avalanche diode (SPAD) sensors implemented with complementary metal-oxide-semiconductor (CMOS) technology…
(more)
▼ Biomedicine requires highly sensitive and efficient light sensors to analyse light-tissue or light-sample interactions. Single-photon avalanche diode (SPAD) sensors implemented with complementary metal-oxide-semiconductor (CMOS) technology have a growing range of applications in this field. Single-photon detection coupled with integrated timing circuits enables us to timestamp each detected photon with high temporal resolution (down to picoseconds). Arrays of SPAD based pixels and CMOS technology offer massively parallel time-resolved single-photon counting for spectrally and temporally resolved analysis of various light phenomena. This thesis examines how time-resolved CMOS SPAD based line sensors with per pixel timing circuits can be utilized to advance biophotonic applications. The study focuses on improving the existing techniques of fluorescence and Raman spectroscopy, and demonstrates for the first time CMOS SPAD based detection in optical coherence tomography (OCT). A novel detection scheme is proposed combining low-coherence interferometry and time-resolved photon counting. In this approach the interferometric information is revealed from spectral intensity measurements, which is supplemented by time-stamping of the photons building up the spectra. Two CMOS SPAD line sensors (Ra-I and its improved version, Ra-II) were characterized and the effect of their parameters on the selected techniques was analysed. The thesis demonstrates the deployment of the Ra-I line sensor in time-resolved fluorescence spectroscopy with indications of the applicability in time-resolved Raman spectroscopy. The work includes integration of the sensor with surrounding electrical and optical systems, and the implementation of firmware and software for controlling the optical setup. As a result, a versatile platform is demonstrated capable of micro- and millisecond sampling of spectral fluorescence lifetime changes in a single transient of fast chemical reactions. OCT operating in the spectral domain traditionally uses CMOS photodiode and charge-coupled device (CCD) based detectors. The applicability of CMOS SPAD sensors is investigated for the first time with focus on the main limitations and related challenges. Finally, a new detection method is proposed relying on both the wave and particle nature of light, recording time-resolved interferometric spectra from a Michelson interferometer. This method offers an alternative approach to analyse luminous effects and improves techniques based on the light’s time of flight. As an example, a proof of concept study is presented for the removal of unwanted reflections from along the sample and the optical path in an OCT setup.
Subjects/Keywords: single-photon avalanche diode sensors; SPAD sensors; complementary metal-oxide-semiconductor technology; CMOS technology; time-resolved single-photon counting; CMOS SPAD based detection; optical coherence tomography
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Kufcsák, A. (2020). Spectrally and temporally resolved single photon counting in advanced biophotonics applications. (Doctoral Dissertation). University of Edinburgh. Retrieved from http://hdl.handle.net/1842/36964
Chicago Manual of Style (16th Edition):
Kufcsák, András. “Spectrally and temporally resolved single photon counting in advanced biophotonics applications.” 2020. Doctoral Dissertation, University of Edinburgh. Accessed April 13, 2021.
http://hdl.handle.net/1842/36964.
MLA Handbook (7th Edition):
Kufcsák, András. “Spectrally and temporally resolved single photon counting in advanced biophotonics applications.” 2020. Web. 13 Apr 2021.
Vancouver:
Kufcsák A. Spectrally and temporally resolved single photon counting in advanced biophotonics applications. [Internet] [Doctoral dissertation]. University of Edinburgh; 2020. [cited 2021 Apr 13].
Available from: http://hdl.handle.net/1842/36964.
Council of Science Editors:
Kufcsák A. Spectrally and temporally resolved single photon counting in advanced biophotonics applications. [Doctoral Dissertation]. University of Edinburgh; 2020. Available from: http://hdl.handle.net/1842/36964
University of Edinburgh
5.
Kufcsák, András.
Spectrally and temporally resolved single photon counting in advanced biophotonics applications.
Degree: PhD, 2020, University of Edinburgh
URL: https://doi.org/10.7488/era/265
;
https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.802383
► Biomedicine requires highly sensitive and efficient light sensors to analyse light-tissue or light-sample interactions. Single-photon avalanche diode (SPAD) sensors implemented with complementary metal-oxide-semiconductor (CMOS) technology…
(more)
▼ Biomedicine requires highly sensitive and efficient light sensors to analyse light-tissue or light-sample interactions. Single-photon avalanche diode (SPAD) sensors implemented with complementary metal-oxide-semiconductor (CMOS) technology have a growing range of applications in this field. Single-photon detection coupled with integrated timing circuits enables us to timestamp each detected photon with high temporal resolution (down to picoseconds). Arrays of SPAD based pixels and CMOS technology offer massively parallel time-resolved single-photon counting for spectrally and temporally resolved analysis of various light phenomena. This thesis examines how time-resolved CMOS SPAD based line sensors with per pixel timing circuits can be utilized to advance biophotonic applications. The study focuses on improving the existing techniques of fluorescence and Raman spectroscopy, and demonstrates for the first time CMOS SPAD based detection in optical coherence tomography (OCT). A novel detection scheme is proposed combining low-coherence interferometry and time-resolved photon counting. In this approach the interferometric information is revealed from spectral intensity measurements, which is supplemented by time-stamping of the photons building up the spectra. Two CMOS SPAD line sensors (Ra-I and its improved version, Ra-II) were characterized and the effect of their parameters on the selected techniques was analysed. The thesis demonstrates the deployment of the Ra-I line sensor in time-resolved fluorescence spectroscopy with indications of the applicability in time-resolved Raman spectroscopy. The work includes integration of the sensor with surrounding electrical and optical systems, and the implementation of firmware and software for controlling the optical setup. As a result, a versatile platform is demonstrated capable of micro- and millisecond sampling of spectral fluorescence lifetime changes in a single transient of fast chemical reactions. OCT operating in the spectral domain traditionally uses CMOS photodiode and charge-coupled device (CCD) based detectors. The applicability of CMOS SPAD sensors is investigated for the first time with focus on the main limitations and related challenges. Finally, a new detection method is proposed relying on both the wave and particle nature of light, recording time-resolved interferometric spectra from a Michelson interferometer. This method offers an alternative approach to analyse luminous effects and improves techniques based on the light’s time of flight. As an example, a proof of concept study is presented for the removal of unwanted reflections from along the sample and the optical path in an OCT setup.
Subjects/Keywords: single-photon avalanche diode sensors; SPAD sensors; complementary metal-oxide-semiconductor technology; CMOS technology; time-resolved single-photon counting; CMOS SPAD based detection; optical coherence tomography
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Kufcsák, A. (2020). Spectrally and temporally resolved single photon counting in advanced biophotonics applications. (Doctoral Dissertation). University of Edinburgh. Retrieved from https://doi.org/10.7488/era/265 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.802383
Chicago Manual of Style (16th Edition):
Kufcsák, András. “Spectrally and temporally resolved single photon counting in advanced biophotonics applications.” 2020. Doctoral Dissertation, University of Edinburgh. Accessed April 13, 2021.
https://doi.org/10.7488/era/265 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.802383.
MLA Handbook (7th Edition):
Kufcsák, András. “Spectrally and temporally resolved single photon counting in advanced biophotonics applications.” 2020. Web. 13 Apr 2021.
Vancouver:
Kufcsák A. Spectrally and temporally resolved single photon counting in advanced biophotonics applications. [Internet] [Doctoral dissertation]. University of Edinburgh; 2020. [cited 2021 Apr 13].
Available from: https://doi.org/10.7488/era/265 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.802383.
Council of Science Editors:
Kufcsák A. Spectrally and temporally resolved single photon counting in advanced biophotonics applications. [Doctoral Dissertation]. University of Edinburgh; 2020. Available from: https://doi.org/10.7488/era/265 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.802383
McMaster University
6.
Khan, Ferdous Karim.
Design, Fabrication and Analysis of Broadly Tunable Asymmetric Multiple Quantum Well Coupled Cavity Diode Lasers.
Degree: PhD, 2010, McMaster University
URL: http://hdl.handle.net/11375/19078
► A detailed analysis of coupled cavity semiconductor lasers with asymmetric multiple quantum well (AMQW) active regions is presented in this thesis. The analysis involved…
(more)
▼ A detailed analysis of coupled cavity semiconductor lasers with asymmetric multiple quantum well (AMQW) active regions is presented in this thesis. The analysis involved design, fabrication, characterization, and simulation of these devices. Although the coupled cavity devices can be multi sectioned, the devices discussed in this thesis are two sectioned. A below threshold model for an AMQW coupled cavity device is developed. Non-linear fits of the below threshold spectral data to that obtained from the model were used to extract optimized device parameters. These fits helped to create an understanding of the operation of the devices and paved the way for improved device performance. Optimized device parameters obtained from the below threshold model were later used as input parameters in the development of an above threshold model. This model verified the wavelength selection mechanism employed by coupled cavity diode lasers and predicted the longitudinal modes for sets of injection currents. Optical coherence tomography (OCT) is an application where much interest has recently been drawn. The coupled cavity devices fabricated in this work applied with proper modulation of the injection currents and followed by subsequent time averaging have demonstrated short coherence length (-15 μm) and can be an excellent source for synthesized OCT. Rapid wavelength switching (-70 ns, the measurement was limited by detector response time) over the whole range has also been experimentally shown. Because of the high speed (relative to mechanical) wavelength switching ability, AMQW coupled cavity devices have the potential for applications requiring real time measurements including real time synthesized OCT.
Thesis
Doctor of Philosophy (PhD)
Advisors/Committee Members: Cassidy, Daniel T., Engineering Physics.
Subjects/Keywords: coupled cavity semiconductor laser; asymmetric multiple quantum well; optical coherence technology; wavelength switching
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Khan, F. K. (2010). Design, Fabrication and Analysis of Broadly Tunable Asymmetric Multiple Quantum Well Coupled Cavity Diode Lasers. (Doctoral Dissertation). McMaster University. Retrieved from http://hdl.handle.net/11375/19078
Chicago Manual of Style (16th Edition):
Khan, Ferdous Karim. “Design, Fabrication and Analysis of Broadly Tunable Asymmetric Multiple Quantum Well Coupled Cavity Diode Lasers.” 2010. Doctoral Dissertation, McMaster University. Accessed April 13, 2021.
http://hdl.handle.net/11375/19078.
MLA Handbook (7th Edition):
Khan, Ferdous Karim. “Design, Fabrication and Analysis of Broadly Tunable Asymmetric Multiple Quantum Well Coupled Cavity Diode Lasers.” 2010. Web. 13 Apr 2021.
Vancouver:
Khan FK. Design, Fabrication and Analysis of Broadly Tunable Asymmetric Multiple Quantum Well Coupled Cavity Diode Lasers. [Internet] [Doctoral dissertation]. McMaster University; 2010. [cited 2021 Apr 13].
Available from: http://hdl.handle.net/11375/19078.
Council of Science Editors:
Khan FK. Design, Fabrication and Analysis of Broadly Tunable Asymmetric Multiple Quantum Well Coupled Cavity Diode Lasers. [Doctoral Dissertation]. McMaster University; 2010. Available from: http://hdl.handle.net/11375/19078
Linköping University
7.
Freiberger, Manuel.
A time domain optical coherence tomograph for laboratory investigations on phantoms and human skin.
Degree: Biomedical Engineering, 2005, Linköping University
URL: http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-3852
► Optical coherence tomography is an imaging modality with an outstanding resolution. During the project, a time domain OCT system based on a Michelson fibre…
(more)
▼ Optical coherence tomography is an imaging modality with an outstanding resolution. During the project, a time domain OCT system based on a Michelson fibre interferometer was implemented and put into operation. A super-luminescent diode with a centre wavelength of 1295nm and a bandwidth of 45nm was selected as light source and a linear variable delay line as reference. Basic tests were made on phantoms constructed of filter foils and on gel-like agar slices with optical properties similar to human tissue. It was shown that the achievable resolution was at least 36um and can be increased. The system can easily be enhanced to create two-dimensional images.
Optische Kohärenztomographie ist ein bildgebendes Verfahren mit einer hervorragenden räumlichen Auflösung. Im Laufe des Projekts wurde ein OCT-System basierend auf einem faseroptischen Michelson-Interferometer implementiert und in Betrieb genommen. Als Lichtquelle wurde eine Superlumineszenzdiode mit einer Mittenwellenlänge von 1295nm und einer Bandbreite von 45nm gewählt. Eine variable optische Verzögerungsleitung diente als Referenz. Erste Messungen an Filterfolien und gelähnlichen Agarphantomen, die die optischen Eigenschaften von menschlichem Gewebe nachbildeten, lieferten eine räumliche Auflösung von mindestens 36um. Durch die modulare Bauweise ist das System leicht für zweidimensionale Aufnahmen erweiterbar.
Subjects/Keywords: Optical coherence tomography; low-coherence interferometry; medical imaging; imaging phantoms; Michelson interferometer; Optische Kohärenztomographie; Teilkohärenz-Interferometrie; medizinische Bildgebung; Gewebephantome; Michelson-Interferometrie; Medical technology; Medicinsk teknik
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Freiberger, M. (2005). A time domain optical coherence tomograph for laboratory investigations on phantoms and human skin. (Thesis). Linköping University. Retrieved from http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-3852
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Freiberger, Manuel. “A time domain optical coherence tomograph for laboratory investigations on phantoms and human skin.” 2005. Thesis, Linköping University. Accessed April 13, 2021.
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-3852.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Freiberger, Manuel. “A time domain optical coherence tomograph for laboratory investigations on phantoms and human skin.” 2005. Web. 13 Apr 2021.
Vancouver:
Freiberger M. A time domain optical coherence tomograph for laboratory investigations on phantoms and human skin. [Internet] [Thesis]. Linköping University; 2005. [cited 2021 Apr 13].
Available from: http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-3852.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Freiberger M. A time domain optical coherence tomograph for laboratory investigations on phantoms and human skin. [Thesis]. Linköping University; 2005. Available from: http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-3852
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
. 
Open Access Theses and Dissertations