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Texas A&M University
1.
Keith, Ashley Brooke.
Consequences of Maternal Nutrient Restriction on Ovine Placental Development.
Degree: PhD, Physiology of Reproduction, 2015, Texas A&M University
URL: http://hdl.handle.net/1969.1/155706
► Maternal nutrient intake and partitioning, uteroplacental blood flow, nutrient transporter activity, and fetoplacental metabolism mediate nutrient delivery to the fetus. Inadequate delivery of nutrients results…
(more)
▼ Maternal
nutrient intake and partitioning, uteroplacental blood flow,
nutrient transporter activity, and fetoplacental metabolism mediate
nutrient delivery to the fetus. Inadequate delivery of nutrients results in intrauterine growth
restriction (IUGR), a leading cause of neonatal morbidity and mortality. The present studies exploited natural population variance in
nutrient-restricted (NR) ewes to identify subpopulations of IUGR and non-IUGR fetuses as subjects for research to elucidate adaptive mechanisms of fetal-placental development.
Singleton pregnancies were generated by embryo transfer and assigned to receive either 50% (n=24) or 100% (n=7) of the National Research Council’s (NRC) recommended dietary intake from Day 35 to Day 125 of gestation, at which time ewes were necropsied. Maternal weight did not correlate with fetal weight; therefore, differences in development of the six heaviest (NR non-IUGR) and six lightest (NR IUGR) fetuses from NR ewes, as well as the seven fetuses from control ewes were compared. Mean weights of NR IUGR fetuses (2.8±0.1 kg) were lower (P<0.05) than for control (4.0±0.1 kg) and NR non-IUGR (4.1±0.1 kg) fetuses.
The first study investigated potential mechanisms regulating
nutrient availability for fetuses. Results indicated that normal fetal growth in a subpopulation of NR ewes is associated with enhanced delivery of a number of amino acids and their metabolites into the fetal circulation, which may at least partially result from up-regulation of expression of amino acid transporter mRNAs in the placentome. The second study elucidated potential physiological mechanisms regulating placental growth and development in ewes having NR IUGR and NR non-IUGR fetuses. Results suggest that placentome morphology and angiogenic growth factor expression varies in response to maternal nutritional challenge during pregnancy and may play critical roles in regulating fetal growth. The third study was conducted to capitalize on natural population variance in NR ewes to identify novel factors regulating placental growth and function. Results suggest that enhanced fetal growth in NR non-IUGR pregnancies is associated with an altered expression of genes related to immune response and function in the placentome. Collectively, results of these studies suggest that enhanced fetal growth in a subset of NR ewes is associated with enhanced expression of select
nutrient transporters and angiogenic factors, increased
nutrient availability to the fetus, altered placentome morphology, and an altered immune response within the placentomes of those ewes.
Advisors/Committee Members: Satterfield, Michael C (advisor), Dunlap, Kathrin A (advisor), Bazer, Fuller W (committee member), Wu, Guoyao (committee member), Golding, Michael C (committee member).
Subjects/Keywords: placenta; nutrient restriction; IUGR; sheep
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APA (6th Edition):
Keith, A. B. (2015). Consequences of Maternal Nutrient Restriction on Ovine Placental Development. (Doctoral Dissertation). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/155706
Chicago Manual of Style (16th Edition):
Keith, Ashley Brooke. “Consequences of Maternal Nutrient Restriction on Ovine Placental Development.” 2015. Doctoral Dissertation, Texas A&M University. Accessed January 16, 2021.
http://hdl.handle.net/1969.1/155706.
MLA Handbook (7th Edition):
Keith, Ashley Brooke. “Consequences of Maternal Nutrient Restriction on Ovine Placental Development.” 2015. Web. 16 Jan 2021.
Vancouver:
Keith AB. Consequences of Maternal Nutrient Restriction on Ovine Placental Development. [Internet] [Doctoral dissertation]. Texas A&M University; 2015. [cited 2021 Jan 16].
Available from: http://hdl.handle.net/1969.1/155706.
Council of Science Editors:
Keith AB. Consequences of Maternal Nutrient Restriction on Ovine Placental Development. [Doctoral Dissertation]. Texas A&M University; 2015. Available from: http://hdl.handle.net/1969.1/155706
2.
Taylor, Regina.
EFFECTS OF MATERNAL NUTRIENT RESTRICTION DURING EARLY OR MID-GESTATION ON BOVINE FETAL GROWTH, PLACENTOMES, AND miRNA EXPRESSION.
Degree: MS, Animal and Veterinary Sciences, 2015, Clemson University
URL: https://tigerprints.clemson.edu/all_theses/2221
► Primiparous Angus-cross cows (n = 38) were synchronized using a Co-Synch+CIDR protocol and inseminated with semen from one of two Angus sires. Animals were fed…
(more)
▼ Primiparous Angus-cross cows (n = 38) were synchronized using a Co-Synch+CIDR protocol and inseminated with semen from one of two Angus sires. Animals were fed at 1.3 x (Control [CON]) or 0.55 x (
Nutrient Restricted [NR]) of maintenance energy and protein requirements based on BW (NRC 2000). Diets were fed at either 1.3 x (Control [CON]) or 0.55 x (
Nutrient restricted [NR]) of maintenance energy and crude protein values based on BW (NRC 1996). A subset of animals (n = 16) was fed either NR (n = 8) or C (n = 8) from d 30-110 of gestation. The remaining animals (n = 22) were fed CON (n = 8) d 30-190; NR (n = 7) d 30-110 followed by CON d 110-190; or CON (n = 7) d 30-110 followed by NR d 110-190. Cows were slaughtered on d 110 or d 190 of gestation, when fetal measurements and samples were taken for analysis. Fetal weights and empty fetal weights were also reduced (P = 0.0027, P = 0.0023, respectively) in d 110 NR animals. Fetal weights tended to be reduced (P = 0.07) in NR/CON and CON/NR versus CON/CON cattle. Empty fetal weights were reduced (P = 0.03) in NR/CON and CON/NR versus CON/CON cattle. Abdominal and thoracic circumferences were reduced (P = 0.0265, P = 0.0002, respectively) in d 110 NR animals and were also reduced (P = 0.01 and P = 0.03, respectively) in NR/CON and CON/NR versus CON/CON cattle. Brain weight as a percent of empty fetal weight (P < 0.01) was increased in d 110 NR animals compared with d 110 CON animals. Brain weight as a percent of empty fetal weight was increased (P < 0.001) in NR/CON and CON/NR versus CON/CON cattle. Fetal pancreas weight as a percent of empty fetal weight was reduced (P = 0.06) in NR d 110 cattle. Fetal pancreas weight as a percent of empty fetal weight was reduced (P = 0.04) in CON/NR versus CON/CON cattle (0.062 ± 0.004 versus. 0.079 ± 0.004 %) while NR/CON values (0.069 ± 0.004 %) were intermediate. Fetal perirenal adipose as a percent of empty fetal weight was increased (P = 0.01) in NR d 110 female fetuses. Fetal perirenal adipose as a percent of empty fetal weight was increased (P = 0.003) in NR/CON and CON/NR versus CON/CON cattle. The data show that maternal
nutrient restriction during early or mid gestation causes asymmetrical fetal growth
restriction, regardless if the
restriction is preceded or followed by a period of non-
restriction. RNA was isolated from flash frozen cotyledon samples (3 subsamples/treatment) using the mirVana microRNA Isolation kit and analyzed using a previously validated microarray. MicroRNA expression was analyzed as an ANOVA analysis using appropriate procedures correcting for false discovery rate of microarray data. Of the sequences chosen for microarray, 88 showed significant (P < 0.05) differential expression between d 190 treatment groups. A total of 40 miRNAs were upregulated in the control group compared with both
nutrient restricted groups and a total of 26 miRNAs were upregulated in the
nutrient restricted groups compared with the control group. In d 110 animals, 142 showed significant (P < 0.05) differential expression between…
Advisors/Committee Members: Long, Nathan M, Hill, Gary M, Strickland, James R, Pratt, Scott L.
Subjects/Keywords: Fetal programming; miRNA expression; Nutrient restriction
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
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APA (6th Edition):
Taylor, R. (2015). EFFECTS OF MATERNAL NUTRIENT RESTRICTION DURING EARLY OR MID-GESTATION ON BOVINE FETAL GROWTH, PLACENTOMES, AND miRNA EXPRESSION. (Masters Thesis). Clemson University. Retrieved from https://tigerprints.clemson.edu/all_theses/2221
Chicago Manual of Style (16th Edition):
Taylor, Regina. “EFFECTS OF MATERNAL NUTRIENT RESTRICTION DURING EARLY OR MID-GESTATION ON BOVINE FETAL GROWTH, PLACENTOMES, AND miRNA EXPRESSION.” 2015. Masters Thesis, Clemson University. Accessed January 16, 2021.
https://tigerprints.clemson.edu/all_theses/2221.
MLA Handbook (7th Edition):
Taylor, Regina. “EFFECTS OF MATERNAL NUTRIENT RESTRICTION DURING EARLY OR MID-GESTATION ON BOVINE FETAL GROWTH, PLACENTOMES, AND miRNA EXPRESSION.” 2015. Web. 16 Jan 2021.
Vancouver:
Taylor R. EFFECTS OF MATERNAL NUTRIENT RESTRICTION DURING EARLY OR MID-GESTATION ON BOVINE FETAL GROWTH, PLACENTOMES, AND miRNA EXPRESSION. [Internet] [Masters thesis]. Clemson University; 2015. [cited 2021 Jan 16].
Available from: https://tigerprints.clemson.edu/all_theses/2221.
Council of Science Editors:
Taylor R. EFFECTS OF MATERNAL NUTRIENT RESTRICTION DURING EARLY OR MID-GESTATION ON BOVINE FETAL GROWTH, PLACENTOMES, AND miRNA EXPRESSION. [Masters Thesis]. Clemson University; 2015. Available from: https://tigerprints.clemson.edu/all_theses/2221

Colorado State University
3.
Brenman, Kristina Anne.
Effect of dam nutrient deprivation on lamb carcass characteristics, retail yields, and nutrient composition, The.
Degree: MS(M.S.), Animal Sciences, 2012, Colorado State University
URL: http://hdl.handle.net/10217/65310
► The objective of this study was to determine the effect of dam nutrient restriction on offspring carcass characteristics, retail cut yields, and nutrient composition. Forty…
(more)
▼ The objective of this study was to determine the effect of dam
nutrient restriction on offspring carcass characteristics, retail cut yields, and
nutrient composition. Forty one western white rams and ewes were obtained from a previous Colorado State University study of dam
nutrient restriction. Prior to gestation, dams were fed 100% of their
nutrient requirements. The diet of dams was a vitamin-mineral rich pelleted beet-pulp (77.8% total digestible nutrients [TDN], 90.0% dry matter [DM], and 9.4% crude protein [CP]). At 28 days gestational age, dams were randomly assigned to individual pens and separated into three different treatments: control (100%
nutrient requirements), half ration (fed 50% of their
nutrient requirements from day 28 until term), and realimented (fed 50% of their
nutrient requirements from day 28 until day 78, and then slowly realimented back to 100% for the remainder of gestation). All twin lambs were slaughtered, and hot carcass weight, 12th rib fat, body wall thickness, adjusted fat, ribeye area, ribeye marbling, leg score, leg circumference, conformation, flank streaking, flank firmness, flank color, kidney fat weight, L*, a*, and b* were obtained. After all lambs were slaughtered, one half of each lamb carcass was fabricated in the following subprimals: rack, roast ready, frenched PSO 3x1" (IMPS 204C); shoulder, square-cut, boneless (IMPS 208); Denver ribs, skirt-off (IMPS 209A); Foreshank (IMPS 210); loin, short-cut, trimmed PSO 0x0" (IMPS 232A); flank untrimmed (IMPS 232E); leg, hindshank (IMPS 233F); and leg, shank-off, boneless (IMPS 234A). Lastly, all lambs were utilized to determine dry matter, moisture, crude protein, crude fat, ash, vitamins A and E, trace minerals, and fatty acids. No interactions were found between treatment and gender for any characteristic, so treatment and gender were analyzed separately. Lambs of ewes that were nutritionally restricted were smaller in size with less fat. Lambs of the realimented group had more fat than either the control or the half ration groups. Rams had more percent lean content than ewes, which was to be expected. Results of this study provide insight on the effect of
nutrient restriction on lamb growth and development, as well as
nutrient content of American lamb.
Advisors/Committee Members: Belk, Keith (advisor), Woerner, Dale (committee member), Engle, Terry (committee member), Mykles, Donald (committee member).
Subjects/Keywords: nutrient restriction; nutrient composition; retail cuts; carcass characteristics; lamb
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APA ·
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APA (6th Edition):
Brenman, K. A. (2012). Effect of dam nutrient deprivation on lamb carcass characteristics, retail yields, and nutrient composition, The. (Masters Thesis). Colorado State University. Retrieved from http://hdl.handle.net/10217/65310
Chicago Manual of Style (16th Edition):
Brenman, Kristina Anne. “Effect of dam nutrient deprivation on lamb carcass characteristics, retail yields, and nutrient composition, The.” 2012. Masters Thesis, Colorado State University. Accessed January 16, 2021.
http://hdl.handle.net/10217/65310.
MLA Handbook (7th Edition):
Brenman, Kristina Anne. “Effect of dam nutrient deprivation on lamb carcass characteristics, retail yields, and nutrient composition, The.” 2012. Web. 16 Jan 2021.
Vancouver:
Brenman KA. Effect of dam nutrient deprivation on lamb carcass characteristics, retail yields, and nutrient composition, The. [Internet] [Masters thesis]. Colorado State University; 2012. [cited 2021 Jan 16].
Available from: http://hdl.handle.net/10217/65310.
Council of Science Editors:
Brenman KA. Effect of dam nutrient deprivation on lamb carcass characteristics, retail yields, and nutrient composition, The. [Masters Thesis]. Colorado State University; 2012. Available from: http://hdl.handle.net/10217/65310

Utah State University
4.
Quarnberg, Shelby M.
Effects of Mid-Gestation Nutrient Restriction on Carcass Measurements and Meat Quality of Resultant Offspring.
Degree: MS, Nutrition, Dietetics, and Food Sciences, 2019, Utah State University
URL: https://digitalcommons.usu.edu/etd/7508
► The goal of this study was to investigate feedlot performance and meat quality of calves born to cows that underwent a nutrient restriction during…
(more)
▼ The goal of this study was to investigate feedlot performance and meat quality of calves born to cows that underwent a
nutrient restriction during the second trimester of gestation which may be occurring in the Intermountain West. Thirty-four angus influenced calves from the same sire were used for this study. The calves were born from cows that were separated into either a maintenance group, and kept on an irrigated pasture, or a restricted group, that was placed on an unirrigated pasture and allowed to lose one body condition score during the second trimester of pregnancy. This study begins with the calves on day 85 of the finishing portion of the feedlot phase. During the finishing feedlot phase, calves were individually housed, fed ad libitum, and feedlot performance measurements were taken every 28 days. Carcasses from the calves were evaluated for yield and quality. A loin from each carcass was collected, aged, frozen, and cut into individually packaged steaks that were used to assess meat quality. There was no difference in feedlot performance and carcass measurements for either maintenance and restricted calves. Meat quality measurements revealed no difference in color, instrumental tenderness values, or composition of steaks from either group. A trained sensory panel found that ten characteristics of flavor were similar for both treatments. There was however, a trend for steaks from
nutrient restricted cattle to have more of a bloody/serumy flavor. The trained sensory panel also found that there was a difference in tenderness of steaks from
nutrient restricted animals being perceived as more tender than animals from maintenance cows. The results of this study demonstrate that
nutrient restriction during mid-gestation does not have negative effects on feedlot performance, carcass characteristics, or meat quality measurements. These results also indicate that steaks from calves born to
nutrient restricted cows may be perceived as more tender.
Advisors/Committee Members: Jerrad F. Legako, Kara J. Thornton, Chuck E. Carpenter, ;.
Subjects/Keywords: mid gestation; nutrient restriction; beef; feedlot; meat quality; carcass measurements; Nutrition
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
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APA (6th Edition):
Quarnberg, S. M. (2019). Effects of Mid-Gestation Nutrient Restriction on Carcass Measurements and Meat Quality of Resultant Offspring. (Masters Thesis). Utah State University. Retrieved from https://digitalcommons.usu.edu/etd/7508
Chicago Manual of Style (16th Edition):
Quarnberg, Shelby M. “Effects of Mid-Gestation Nutrient Restriction on Carcass Measurements and Meat Quality of Resultant Offspring.” 2019. Masters Thesis, Utah State University. Accessed January 16, 2021.
https://digitalcommons.usu.edu/etd/7508.
MLA Handbook (7th Edition):
Quarnberg, Shelby M. “Effects of Mid-Gestation Nutrient Restriction on Carcass Measurements and Meat Quality of Resultant Offspring.” 2019. Web. 16 Jan 2021.
Vancouver:
Quarnberg SM. Effects of Mid-Gestation Nutrient Restriction on Carcass Measurements and Meat Quality of Resultant Offspring. [Internet] [Masters thesis]. Utah State University; 2019. [cited 2021 Jan 16].
Available from: https://digitalcommons.usu.edu/etd/7508.
Council of Science Editors:
Quarnberg SM. Effects of Mid-Gestation Nutrient Restriction on Carcass Measurements and Meat Quality of Resultant Offspring. [Masters Thesis]. Utah State University; 2019. Available from: https://digitalcommons.usu.edu/etd/7508

University of Western Ontario
5.
Ghaly, Andrew.
Maternal Nutrient Restriction in Pregnant Guinea Pigs and the Impact on Fetal Growth and Brain Development.
Degree: 2017, University of Western Ontario
URL: https://ir.lib.uwo.ca/etd/4359
► Maternal nutrient restriction (MNR) in guinea pigs results in placental structural abnormalities that reduce nutrient transport contributing to fetal growth restriction (FGR). However, whether brain…
(more)
▼ Maternal nutrient restriction (MNR) in guinea pigs results in placental structural abnormalities that reduce nutrient transport contributing to fetal growth restriction (FGR). However, whether brain weights are similarly reduced, or preserved by “brain sparing” mechanisms, and whether energy levels are depleted leading to membrane failure and overt injury remains unknown. Guinea pig sows were fed ad libitum (Controls) or 70% of the control diet pre-pregnant switching to 90% at mid-pregnancy (MNR). Animals were necropsied near term for fetal growth measures and fetal brains were assessed for markers of necrotic cell injury, apoptotic cell injury, endoplasmic reticulum stress, and altered development proteins. MNR resulted in FGR with brains that are large relative to body weight and livers that are small relative to body weight, which suggests a degree of blood flow redistribution. These fetuses have reduced brain weights, but with substantial brain sparing, and with no increased necrotic cell injury and no changes in synaptic development, indicating that the threshold for membrane failure or aberrant development with energy depletion has likely not been reached. However, apoptotic indices were increased in FGR-MNR cohort compared to appropriate for gestational age (AGA)-control cohort and more so in males than females. Changes in apoptosis were primarily in hippocampal regions and were not accompanied by significant changes of protein levels of investigated pro-apoptotic factors.
Subjects/Keywords: Maternal Nutrient Restriction (MNR); Fetal Growth Restriction (FGR); Fetal Programming; Undernutrition; Brain Injury; Brain Development; Hypoxia.; Developmental Neuroscience
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Ghaly, A. (2017). Maternal Nutrient Restriction in Pregnant Guinea Pigs and the Impact on Fetal Growth and Brain Development. (Thesis). University of Western Ontario. Retrieved from https://ir.lib.uwo.ca/etd/4359
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Ghaly, Andrew. “Maternal Nutrient Restriction in Pregnant Guinea Pigs and the Impact on Fetal Growth and Brain Development.” 2017. Thesis, University of Western Ontario. Accessed January 16, 2021.
https://ir.lib.uwo.ca/etd/4359.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Ghaly, Andrew. “Maternal Nutrient Restriction in Pregnant Guinea Pigs and the Impact on Fetal Growth and Brain Development.” 2017. Web. 16 Jan 2021.
Vancouver:
Ghaly A. Maternal Nutrient Restriction in Pregnant Guinea Pigs and the Impact on Fetal Growth and Brain Development. [Internet] [Thesis]. University of Western Ontario; 2017. [cited 2021 Jan 16].
Available from: https://ir.lib.uwo.ca/etd/4359.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Ghaly A. Maternal Nutrient Restriction in Pregnant Guinea Pigs and the Impact on Fetal Growth and Brain Development. [Thesis]. University of Western Ontario; 2017. Available from: https://ir.lib.uwo.ca/etd/4359
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Western Ontario
6.
Radford, Bethany N.
Metabolic and Expression Changes Associated with a Mouse Model of Intrauterine Growth Restriction (IUGR).
Degree: 2018, University of Western Ontario
URL: https://ir.lib.uwo.ca/etd/6023
► Intrauterine growth restriction (IUGR) is a pregnancy condition where fetal growth is suboptimal, resulting in an infant born small for gestational age (<10th percentile) and…
(more)
▼ Intrauterine growth restriction (IUGR) is a pregnancy condition where fetal growth is suboptimal, resulting in an infant born small for gestational age (<10th percentile) and is associated with metabolic disorders such as type 2 diabetes in adulthood. This study aims to understand tissue-specific adaptations to fetal undernutrition which predispose the individual to metabolic disorders in adulthood. A model of growth restriction in mice was established using 70% of maternal ad libitum total food (g) (E6.5-birth). At weaning, male offspring received standard chow or a HFHS diet. Body weight and random blood glucose levels were measured at 6 months. To assess metabolism at 6 or 7 months, glucose tolerance, pyruvate challenge and hepatic portal vein insulin challenge tests were administered and serum peptide markers for obesity and diabetes were measured. Metabolic cages were also used at 2 and 7 months to measure activity, food intake and respiratory exchange ratios (RERs). Adult liver, adipose and skeletal muscle and fetal liver was collected for RNA sequencing. Maternal nutrient restricted (MNR) offspring were growth restricted with disproportionately smaller fetal livers. 19% of standard chow-fed MNR offspring became glucose intolerant. On an isocaloric high-fat high-sugar diet no differences in MNR growth or glucose metabolism were detected. However, RERs were reduced at all timepoints in MNR on a HFHS relative to MNR on standard chow. Differences in transcription of genes involved in hypoxia signalling were detected and HIF-2a and HIF-3a proteins were increased in fetal liver of MNR offspring. Genes differentially expressed in the fetus were not differentially expressed at 6 months. Gene expression of metabolically regulatory transcripts in liver, adipose and skeletal muscle did not differ in all MNR and glucose intolerant MNR relative to controls. This model results in a susceptible and non-susceptible population of maternal nutrient restricted offspring and supports the concept of hypoxia signalling contributing to fetal adaptations. Understanding adaptations in hepatic hypoxia signalling in response to fetal undernutrition and how they vary in susceptible and unsusceptible populations will provide insight into how fetal nutrition can influence adult metabolism.
Subjects/Keywords: Growth restriction; glucose tolerance; gene expression; hypoxia; HIF-2a; maternal nutrient restriction; Disease Modeling; Medical Molecular Biology; Nutritional and Metabolic Diseases
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Radford, B. N. (2018). Metabolic and Expression Changes Associated with a Mouse Model of Intrauterine Growth Restriction (IUGR). (Thesis). University of Western Ontario. Retrieved from https://ir.lib.uwo.ca/etd/6023
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Radford, Bethany N. “Metabolic and Expression Changes Associated with a Mouse Model of Intrauterine Growth Restriction (IUGR).” 2018. Thesis, University of Western Ontario. Accessed January 16, 2021.
https://ir.lib.uwo.ca/etd/6023.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Radford, Bethany N. “Metabolic and Expression Changes Associated with a Mouse Model of Intrauterine Growth Restriction (IUGR).” 2018. Web. 16 Jan 2021.
Vancouver:
Radford BN. Metabolic and Expression Changes Associated with a Mouse Model of Intrauterine Growth Restriction (IUGR). [Internet] [Thesis]. University of Western Ontario; 2018. [cited 2021 Jan 16].
Available from: https://ir.lib.uwo.ca/etd/6023.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Radford BN. Metabolic and Expression Changes Associated with a Mouse Model of Intrauterine Growth Restriction (IUGR). [Thesis]. University of Western Ontario; 2018. Available from: https://ir.lib.uwo.ca/etd/6023
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Western Ontario
7.
Nevin, Catherine.
Maternal Nutrient Restriction with Fetal Growth Restriction in Guinea Pigs Impacts Brain Development and Neuroimaging Correlates in Neonatal Offspring.
Degree: 2016, University of Western Ontario
URL: https://ir.lib.uwo.ca/etd/4192
► Aberrant brain development in utero accompanied by fetal growth restriction (FGR) increases the risk of neurodevelopmental disorders in later life. However there are limited non-invasive…
(more)
▼ Aberrant brain development in utero accompanied by fetal growth restriction (FGR) increases the risk of neurodevelopmental disorders in later life. However there are limited non-invasive biomarkers in the brain for the early identification of said neurodevelopmental disorders in an animal model of FGR. Guinea pig sows were fed either ad libitum (Control) or 70% of the control diet pre-pregnancy, increasing to 90% at mid-pregnancy (MNR) creating appropriately grown (AGA) Control and FGR-MNR neonates, respectively. Three to four weeks corrected post-natal age, neonates were imaged using magnetic resonance imaging (MRI) and spectroscopy (MRS) techniques, and were killed 48-72 hours later for histological analysis. FGR-MNR neonates had smaller brain weights, whole brain volume, hippocampal volume and lateral ventricle volume, which correlate to histological findings. While there is a reduction in the hippocampal volume, there are no differences in hippocampus metabolite ratios between the AGA-Control and FGR-MNR neonates. Interestingly, there was a reduction in the width of the stratum oriens and stratum radiatum in the hippocampus proper, as well as the width of the polymorphic layer in the dentate gyrus, with no changes in pyramidal and granule cell number in the FGR-MNR neonates compared to AGA-Control neonates. In conclusion, MNR in guinea pigs produces FGR neonates that display catch up growth and structural differences in the brains while no changes in the metabolite levels in the hippocampal region of the brain. Together these results involve MRI and MRS as reliable imaging tools to detect the presence of brain injury for the future use of biomarkers for neurodevelopmental disorders and potential therapeutic interventions.
Subjects/Keywords: Fetal Growth Restriction; Maternal Nutrient Restriction; Brain Development; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Guinea Pig; Medical Physiology
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Nevin, C. (2016). Maternal Nutrient Restriction with Fetal Growth Restriction in Guinea Pigs Impacts Brain Development and Neuroimaging Correlates in Neonatal Offspring. (Thesis). University of Western Ontario. Retrieved from https://ir.lib.uwo.ca/etd/4192
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Nevin, Catherine. “Maternal Nutrient Restriction with Fetal Growth Restriction in Guinea Pigs Impacts Brain Development and Neuroimaging Correlates in Neonatal Offspring.” 2016. Thesis, University of Western Ontario. Accessed January 16, 2021.
https://ir.lib.uwo.ca/etd/4192.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Nevin, Catherine. “Maternal Nutrient Restriction with Fetal Growth Restriction in Guinea Pigs Impacts Brain Development and Neuroimaging Correlates in Neonatal Offspring.” 2016. Web. 16 Jan 2021.
Vancouver:
Nevin C. Maternal Nutrient Restriction with Fetal Growth Restriction in Guinea Pigs Impacts Brain Development and Neuroimaging Correlates in Neonatal Offspring. [Internet] [Thesis]. University of Western Ontario; 2016. [cited 2021 Jan 16].
Available from: https://ir.lib.uwo.ca/etd/4192.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Nevin C. Maternal Nutrient Restriction with Fetal Growth Restriction in Guinea Pigs Impacts Brain Development and Neuroimaging Correlates in Neonatal Offspring. [Thesis]. University of Western Ontario; 2016. Available from: https://ir.lib.uwo.ca/etd/4192
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Pretoria
8.
[No author].
Circulating glucose responses in early lactation dairy
cows to dietary restriction and rbST treatment
.
Degree: 2011, University of Pretoria
URL: http://upetd.up.ac.za/thesis/available/etd-10222009-135500/
► Galactopoietic effects of somatotropin are the result of IGF-I and require high-quality nutrient intake. This study investigated short-term partitioning effects during recombinant bovine somatotropin (bST)…
(more)
▼ Galactopoietic effects of somatotropin are the
result of IGF-I and require high-quality
nutrient intake. This
study investigated short-term partitioning effects during
recombinant bovine somatotropin (bST) administration in high
yielding early lactation dairy cows. Administration of recombinant
bST has been shown generally to alter results of metabolic tests in
the face of unchanged basal glucose and insulin concentrations. Ten
multiparous Holstein cows were subjected to rbST (Lactotropin®)
and/or feed intake
restriction to 80% of predicted ME requirement
(80% ME). Responses to insulin challenge (0.1 IU porcine insulin/kg
BW. 210 min) and hyperglycaemic clamp (+50 mg/dL whole blood, 120
min) were tested during weeks 8 (control), 9 (rbST ), 11 (80% ME)
and 12 (rbST + 80% ME) postpartum. Plasma and whole blood samples
were assayed for glucose concentrations. The rbST treatment
decreased fasting whole-blood glucose concentration by 9.4%
(P<0.0001), which was likely a remnant of control
hyperglycaemia. Maximum glucose response was 4.0 mg/dL (21.7%)
lower (P<0.0038) and took 6.5 minutes longer to attain
(P<0.0037). Steady-state glucose infusion rate (SSGIR) decreased
by 8.1 % (P<0.0001). The 80% ME treatment decreased glucose
availability by 5 to 6% (P<0.0100), while no glucose responses
were affected. Restricted energy intake during treatment with rbST
resulted in plasma glucose increase by 5.5% (P<0.0001).
Peripheral uptake and utilization of glucose increased by 5.1 %
(P<0.0005). Compared to energy
restriction, 80%ME + rbST did not
alter effects of
nutrient restriction on responses to exogenous
insulin challenge. Effects were small and inconsistent. SSGIR
decreased by 5.0% in the 80% ME + rbST compared to the 80% ME
period (P<0.0004) and the change in the hyperglycaemic clamp in
the absence of an effect in the insulin challenge may be due to
differences in endogenous insulin secretion. The conclusion was
that rbST treatment resulted in altered glucose metabolic
responses, even with restricted energy intake.
Advisors/Committee Members: Prof N H Casey (advisor).
Subjects/Keywords: Insulin resistance;
Glucose clamp;
Recombinant bst;
Early lactation;
Holstein cows;
Nutrient restriction;
UCTD
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
author], [. (2011). Circulating glucose responses in early lactation dairy
cows to dietary restriction and rbST treatment
. (Masters Thesis). University of Pretoria. Retrieved from http://upetd.up.ac.za/thesis/available/etd-10222009-135500/
Chicago Manual of Style (16th Edition):
author], [No. “Circulating glucose responses in early lactation dairy
cows to dietary restriction and rbST treatment
.” 2011. Masters Thesis, University of Pretoria. Accessed January 16, 2021.
http://upetd.up.ac.za/thesis/available/etd-10222009-135500/.
MLA Handbook (7th Edition):
author], [No. “Circulating glucose responses in early lactation dairy
cows to dietary restriction and rbST treatment
.” 2011. Web. 16 Jan 2021.
Vancouver:
author] [. Circulating glucose responses in early lactation dairy
cows to dietary restriction and rbST treatment
. [Internet] [Masters thesis]. University of Pretoria; 2011. [cited 2021 Jan 16].
Available from: http://upetd.up.ac.za/thesis/available/etd-10222009-135500/.
Council of Science Editors:
author] [. Circulating glucose responses in early lactation dairy
cows to dietary restriction and rbST treatment
. [Masters Thesis]. University of Pretoria; 2011. Available from: http://upetd.up.ac.za/thesis/available/etd-10222009-135500/

University of Arkansas
9.
Robinette, Jessica Ann.
Growth Promoting Implants and Nutrient Restriction Prior to Feeding: Effect on Carcass Composition, Carcass Quality, and Consumer Acceptability of Beef.
Degree: MS, 2012, University of Arkansas
URL: https://scholarworks.uark.edu/etd/396
► Implant strategy and nutrient restriction prior to finishing may alter feedlot performance, as well as carcass characteristics and consumer acceptability of beef. The objectives…
(more)
▼ Implant strategy and
nutrient restriction prior to finishing may alter feedlot performance, as well as carcass characteristics and consumer acceptability of beef. The objectives of these studies were to determine the effect of prefinishing implant strategy and plane of nutrition on prefinishing and feedlot performance, carcass characteristics and quality, and consumer acceptability of beef. In 2 experiments, spring-born calves were weaned in the fall (Exp. 1, n =120; and Exp. 2, n = 96) and were either finished as calves (CALF-FED) or placed on a growing program with a target ADG of 0.45 kg/d (RSTR) or 0.91 kg/d (UNRSTR) before finishing. Half of each backgrounding group received moderate potency combination hormonal implants (Synovex-S/H; Pfizer Animal Health, Madison, NJ) before finishing (IMPL). At arrival to the feedyard all cattle were implanted with a moderate potency implant and were reimplanted following 100-d (CALF-FED) or 81-d on feed (UNRSTR and RSTR). Animal performance and carcass characteristics data were analyzed as a split plot design using the Mixed procedure of SAS. Treatment least-squares means were separated using predicted differences. Implantation prefinishing positively affected (P < 0.01) ADG in UNRSTR cattle in the feedlot in Exp. 1, and in all growth treatment groups (P < 0.01) in Exp. 2. Cattle in the UNRSTR treatment had greater (P < 0.01) HCW than CALF-FED or RSTR in both experiments, but there was no effect (P = 0.38) of implant on HCW. Cattle fed as calves had a greater (P = 0.02) marbling score than yearlings in Exp. 1, but there were no differences (P = 0.32) in marbling scores across treatments in Exp. 2. In Exp 1, IMPL cattle tended (P = 0.06) to have a lower marbling score and had reduced (P = 0.03) percentage of cattle grading Choice; however, there was no effect (P ≥ 0.32) of implant strategy on the percentage of cattle grading Choice or on marbling score. Cattle receiving an implant prefinishing had less (P ≤ 0.03) initial and sustained tenderness than cattle that received a delayed implant in Exp 1 and 2.
Advisors/Committee Members: Paul A. Beck, Richard R. Reuter, Jason K. Apple.
Subjects/Keywords: Biological sciences; Carcass quality; Cattle production; Feed efficiency; Implant; Nutrient restriction; Tenderness; Meat Science
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Robinette, J. A. (2012). Growth Promoting Implants and Nutrient Restriction Prior to Feeding: Effect on Carcass Composition, Carcass Quality, and Consumer Acceptability of Beef. (Masters Thesis). University of Arkansas. Retrieved from https://scholarworks.uark.edu/etd/396
Chicago Manual of Style (16th Edition):
Robinette, Jessica Ann. “Growth Promoting Implants and Nutrient Restriction Prior to Feeding: Effect on Carcass Composition, Carcass Quality, and Consumer Acceptability of Beef.” 2012. Masters Thesis, University of Arkansas. Accessed January 16, 2021.
https://scholarworks.uark.edu/etd/396.
MLA Handbook (7th Edition):
Robinette, Jessica Ann. “Growth Promoting Implants and Nutrient Restriction Prior to Feeding: Effect on Carcass Composition, Carcass Quality, and Consumer Acceptability of Beef.” 2012. Web. 16 Jan 2021.
Vancouver:
Robinette JA. Growth Promoting Implants and Nutrient Restriction Prior to Feeding: Effect on Carcass Composition, Carcass Quality, and Consumer Acceptability of Beef. [Internet] [Masters thesis]. University of Arkansas; 2012. [cited 2021 Jan 16].
Available from: https://scholarworks.uark.edu/etd/396.
Council of Science Editors:
Robinette JA. Growth Promoting Implants and Nutrient Restriction Prior to Feeding: Effect on Carcass Composition, Carcass Quality, and Consumer Acceptability of Beef. [Masters Thesis]. University of Arkansas; 2012. Available from: https://scholarworks.uark.edu/etd/396

The Ohio State University
10.
Braden, Jennifer Marie.
The Effects of Simultaneous Thermal and Nutrient Challenge
on Broiler Muscle Growth, Meat Quality, and Underlying Cellular
Mechanisms.
Degree: MS, Animal Sciences, 2019, The Ohio State University
URL: http://rave.ohiolink.edu/etdc/view?acc_num=osu1557148654841507
► In recent years, a variety of muscle myopathies, specifically wooden breast, white striping, and deep pectoralis myopathy, have severely impacted the poultry industry. Although broilers…
(more)
▼ In recent years, a variety of muscle myopathies,
specifically wooden breast, white striping, and deep pectoralis
myopathy, have severely impacted the poultry industry. Although
broilers have become more efficient at producing muscle mass, the
rapid increase in growth has exceeded the structural limits of the
muscle. As a result, myopathies such as wooden breast are commonly
associated with fast-growing, heavy weight broilers. However, there
is little genetic correlation with breast muscle yield, indicating
that environmental factors likely play a vital role. Environmental
factors such as
nutrient restriction and thermal stress can alter
satellite cell populations, which are a type of stem cell
responsible for all post-hatch muscle growth. Changes in the
satellite cells will have long-lasting impacts on muscle
development and meat quality. Although there have been studies that
have elucidated the independent effects of
nutrient restriction and
thermal stress, there is little information regarding the effect of
a simultaneous temperature and nutritional
restriction on satellite
cells, specifically, immediately after hatch, when satellite cells
are the most susceptible to environmental stressors. Since chicks
are rarely exposed to a single stressor, it is important to
understand how simultaneous environmental factors will impact
long-term muscle growth. The effect of a simultaneous post-hatch
feed
restriction and thermal stress on skeletal muscle growth and
meat quality was studied by applying a 20% feed
restriction during
the first week post-hatch. At the time of hatch broiler chicks were
divided into either a 20% feed
restriction group, or given ad
libitum access to feed and held at an ambient temperature of 31°C,
35°C, or 39°C. Gene expression for satellite cell genes Paired Box
Protein 7 (PAX7), Myogenic Factor 5 (MYF5), Myogenic
Differentiation 1 (MYOD1), and Myogenin (MYOG), were measured at d
7, and no significant differences were detected (P > 0.25).
Muscle fiber diameter, number, and histological scoring were also
evaluated and there were no statistical differences observed (P
> 0.20). There was also no statistical difference across
treatments in meat quality characteristics or meat yield at d 42 (P
> 0.05). Feed efficiency and body weight were also recorded from
d 0 to d 42 of the trial. Although there was no difference in feed
efficiency by the end of the trial, there were significant
differences in broiler body weight from d 2 – d 28. Between d 0 – d
7 broilers held at any of the three ambient temperatures had
significantly different body weights, with those held at a control
temperature of 35°C having the heaviest weights, regardless of
nutrient restriction. Birds given a 20% feed
restriction had
significantly lighter body weights between d 2 – d 28 compared to
birds provided ad libitum access to feed regardless of
environmental temperature. On d 2, d 3 and d 4, there was a
significant interaction between both
nutrient restriction and
ambient temperature (P < 0.01). However, by the end of the trial
d 42,…
Advisors/Committee Members: Clark, Daniel (Advisor).
Subjects/Keywords: Agriculture; Animal Sciences; Muscle Development, Meat Quality, Satellite Cell, Muscle
Growth, Body Weight, Myogenic Gene Expression, Muscle Histology,
Temperature Challenge, Thermal Stress, Cold Stress, Nutrient
Restriction, Feed Restriction
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Braden, J. M. (2019). The Effects of Simultaneous Thermal and Nutrient Challenge
on Broiler Muscle Growth, Meat Quality, and Underlying Cellular
Mechanisms. (Masters Thesis). The Ohio State University. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=osu1557148654841507
Chicago Manual of Style (16th Edition):
Braden, Jennifer Marie. “The Effects of Simultaneous Thermal and Nutrient Challenge
on Broiler Muscle Growth, Meat Quality, and Underlying Cellular
Mechanisms.” 2019. Masters Thesis, The Ohio State University. Accessed January 16, 2021.
http://rave.ohiolink.edu/etdc/view?acc_num=osu1557148654841507.
MLA Handbook (7th Edition):
Braden, Jennifer Marie. “The Effects of Simultaneous Thermal and Nutrient Challenge
on Broiler Muscle Growth, Meat Quality, and Underlying Cellular
Mechanisms.” 2019. Web. 16 Jan 2021.
Vancouver:
Braden JM. The Effects of Simultaneous Thermal and Nutrient Challenge
on Broiler Muscle Growth, Meat Quality, and Underlying Cellular
Mechanisms. [Internet] [Masters thesis]. The Ohio State University; 2019. [cited 2021 Jan 16].
Available from: http://rave.ohiolink.edu/etdc/view?acc_num=osu1557148654841507.
Council of Science Editors:
Braden JM. The Effects of Simultaneous Thermal and Nutrient Challenge
on Broiler Muscle Growth, Meat Quality, and Underlying Cellular
Mechanisms. [Masters Thesis]. The Ohio State University; 2019. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=osu1557148654841507
11.
Lumsden, John S.
Autophagy-related gene expression in rainbow trout (Oncorhynchus mykiss) and their role in nutrient restriction in vivo and in vitro.
Degree: MS, Department of Pathobiology, 2017, University of Guelph
URL: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/11620
► The expression of ten autophagy-related genes (ATG4, ATG5, ATG7, ATG9, ATG12, ATG13, ATG16, BECN-1, GABARAP and LC3) was examined in RTgill-W1 (gill epithelial) cells and…
(more)
▼ The expression of ten autophagy-related genes (ATG4, ATG5, ATG7, ATG9, ATG12, ATG13, ATG16, BECN-1, GABARAP and LC3) was examined in RTgill-W1 (gill epithelial) cells and in muscle and liver from rainbow trout (Oncorhynchus mykiss) undergoing serum
nutrient restriction and compared to control groups. Six of these sequences, ATG5, ATG7, ATG9, ATG13, ATG16 and BECN-1, were previously unknown in rainbow trout. The rainbow trout sequences had highest nucleotide sequence similarity with Atlantic salmon and other fish species used for comparison in this study. In serum-restricted RTgill-W1 cells, most autophagy-related genes were significantly expressed at Day 3. In liver from feed-restricted fish, most Atg were significantly upregulated within the first 4 days. Autophagy-related gene expression in muscle was significantly upregulated between Day 8 and 15. Both tissues had a second peak of Atg upregulation at Day 21 suggesting that autophagy is maintained for longer periods of time in fish than previously understood.
Advisors/Committee Members: Lumsden, John S. (advisor).
Subjects/Keywords: autophagy; rainbow; trout; nutrient; restriction; Atg; genes
…manner under nutrient restriction conditions (Sekito et al., 2009). It is… …pathway is induced during stress situations, like nutrient, nitrogen
and/or oxygen restriction… …inhibitor of autophagy. Once TOR is inhibited by nutrient restriction, the
autophagic/lysosomal… …in the case of in vitro experiments, and
after 14 d of nutrient restriction in the case of… …GABARAP were upregulated during nutrient
and serum restriction in rainbow trout (Seiliez et…
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Lumsden, J. S. (2017). Autophagy-related gene expression in rainbow trout (Oncorhynchus mykiss) and their role in nutrient restriction in vivo and in vitro. (Masters Thesis). University of Guelph. Retrieved from https://atrium.lib.uoguelph.ca/xmlui/handle/10214/11620
Chicago Manual of Style (16th Edition):
Lumsden, John S. “Autophagy-related gene expression in rainbow trout (Oncorhynchus mykiss) and their role in nutrient restriction in vivo and in vitro.” 2017. Masters Thesis, University of Guelph. Accessed January 16, 2021.
https://atrium.lib.uoguelph.ca/xmlui/handle/10214/11620.
MLA Handbook (7th Edition):
Lumsden, John S. “Autophagy-related gene expression in rainbow trout (Oncorhynchus mykiss) and their role in nutrient restriction in vivo and in vitro.” 2017. Web. 16 Jan 2021.
Vancouver:
Lumsden JS. Autophagy-related gene expression in rainbow trout (Oncorhynchus mykiss) and their role in nutrient restriction in vivo and in vitro. [Internet] [Masters thesis]. University of Guelph; 2017. [cited 2021 Jan 16].
Available from: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/11620.
Council of Science Editors:
Lumsden JS. Autophagy-related gene expression in rainbow trout (Oncorhynchus mykiss) and their role in nutrient restriction in vivo and in vitro. [Masters Thesis]. University of Guelph; 2017. Available from: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/11620

Utah State University
12.
Ineck, Nikole E.
Effects of Bovine Maternal Nutrient Restriction on Offspring MicroRNA and mRNA Expression and Muscle Fiber Type.
Degree: MS, Animal, Dairy, and Veterinary Sciences, 2020, Utah State University
URL: https://digitalcommons.usu.edu/etd/7778
► For producers in more temperate areas, such as the Intermountain West, poor nutrition during the second trimester of gestation is common due to seasonal…
(more)
▼ For producers in more temperate areas, such as the Intermountain West, poor nutrition during the second trimester of gestation is common due to seasonal changes in forage and
nutrient availability. The majority of muscle fibers are formed and adipogenesis is initiated in the second trimester, making it a critical time for skeletal muscle and adipose development in beef cattle. However, the extent to which these changes persist in the offspring postnatally is unknown. In this study, maternal nutrition was restricted during the second trimester in order to analyze the effects of maternal
nutrient restriction on offspring skeletal muscle growth. Offspring were monitored throughout production postnatally and skeletal muscle samples were taken at weaning, the beginning of the feedlot phase,and at harvest.We investigated whether calves from cows restricted in the second trimester had a different expression of microRNA (miRNA) or messengerRNA (mRNA) known to be downstream targets of those miRNA. We also analyzed mRNA expression of myosin heavy chain (MHC) isoforms to determine whether maternal nutrition in the second trimester impacts muscle fiber type. There were no changes observed in mRNA or MHC expression between the two different treatments at either time point. Differences in expression of several miRNAs important in development of adipose and skeletal muscle were observed between the treatment groups. The findings of this research indicate that maternal nutrition during the second trimester of gestation alters miRNA expression in the skeletal muscle. However, more research is needed to determine exactly how these miRNA impact growth of skeletal muscle postnatally.
Advisors/Committee Members: Kara Thornton-Kurth, Abby Benninghoff, Charles Carpenter, ;.
Subjects/Keywords: fetal programming; mid-gestation; nutrient restriction; miRNA expression; feedlot performance; end-product quality; Animal Sciences; Other Nutrition
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Ineck, N. E. (2020). Effects of Bovine Maternal Nutrient Restriction on Offspring MicroRNA and mRNA Expression and Muscle Fiber Type. (Masters Thesis). Utah State University. Retrieved from https://digitalcommons.usu.edu/etd/7778
Chicago Manual of Style (16th Edition):
Ineck, Nikole E. “Effects of Bovine Maternal Nutrient Restriction on Offspring MicroRNA and mRNA Expression and Muscle Fiber Type.” 2020. Masters Thesis, Utah State University. Accessed January 16, 2021.
https://digitalcommons.usu.edu/etd/7778.
MLA Handbook (7th Edition):
Ineck, Nikole E. “Effects of Bovine Maternal Nutrient Restriction on Offspring MicroRNA and mRNA Expression and Muscle Fiber Type.” 2020. Web. 16 Jan 2021.
Vancouver:
Ineck NE. Effects of Bovine Maternal Nutrient Restriction on Offspring MicroRNA and mRNA Expression and Muscle Fiber Type. [Internet] [Masters thesis]. Utah State University; 2020. [cited 2021 Jan 16].
Available from: https://digitalcommons.usu.edu/etd/7778.
Council of Science Editors:
Ineck NE. Effects of Bovine Maternal Nutrient Restriction on Offspring MicroRNA and mRNA Expression and Muscle Fiber Type. [Masters Thesis]. Utah State University; 2020. Available from: https://digitalcommons.usu.edu/etd/7778

University of Pretoria
13.
Basson, Annelie.
Circulating
glucose responses in early lactation dairy cows to dietary
restriction and rbST treatment.
Degree: Animal and Wildlife
Sciences, 2008, University of Pretoria
URL: http://hdl.handle.net/2263/28939
► Galactopoietic effects of somatotropin are the result of IGF-I and require high-quality nutrient intake. This study investigated short-term partitioning effects during recombinant bovine somatotropin (bST)…
(more)
▼ Galactopoietic effects of somatotropin are the result of
IGF-I and require high-quality
nutrient intake. This study
investigated short-term partitioning effects during recombinant
bovine somatotropin (bST) administration in high yielding early
lactation dairy cows. Administration of recombinant bST has been
shown generally to alter results of metabolic tests in the face of
unchanged basal glucose and insulin concentrations. Ten multiparous
Holstein cows were subjected to rbST (Lactotropin®) and/or feed
intake
restriction to 80% of predicted ME requirement (80% ME).
Responses to insulin challenge (0.1 IU porcine insulin/kg BW. 210
min) and hyperglycaemic clamp (+50 mg/dL whole blood, 120 min) were
tested during weeks 8 (control), 9 (rbST ), 11 (80% ME) and 12
(rbST + 80% ME) postpartum. Plasma and whole blood samples were
assayed for glucose concentrations. The rbST treatment decreased
fasting whole-blood glucose concentration by 9.4% (P<0.0001),
which was likely a remnant of control hyperglycaemia. Maximum
glucose response was 4.0 mg/dL (21.7%) lower (P<0.0038) and took
6.5 minutes longer to attain (P<0.0037). Steady-state glucose
infusion rate (SSGIR) decreased by 8.1 % (P<0.0001). The 80% ME
treatment decreased glucose availability by 5 to 6% (P<0.0100),
while no glucose responses were affected. Restricted energy intake
during treatment with rbST resulted in plasma glucose increase by
5.5% (P<0.0001). Peripheral uptake and utilization of glucose
increased by 5.1 % (P<0.0005). Compared to energy
restriction,
80%ME + rbST did not alter effects of
nutrient restriction on
responses to exogenous insulin challenge. Effects were small and
inconsistent. SSGIR decreased by 5.0% in the 80% ME + rbST compared
to the 80% ME period (P<0.0004) and the change in the
hyperglycaemic clamp in the absence of an effect in the insulin
challenge may be due to differences in endogenous insulin
secretion. The conclusion was that rbST treatment resulted in
altered glucose metabolic responses, even with restricted energy
intake.
Advisors/Committee Members: Casey, N.H. (Norman Henry) (advisor).
Subjects/Keywords: Insulin
resistance; Glucose
clamp; Recombinant
bst; Early
lactation; Holstein
cows; Nutrient
restriction;
UCTD
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Basson, A. (2008). Circulating
glucose responses in early lactation dairy cows to dietary
restriction and rbST treatment. (Masters Thesis). University of Pretoria. Retrieved from http://hdl.handle.net/2263/28939
Chicago Manual of Style (16th Edition):
Basson, Annelie. “Circulating
glucose responses in early lactation dairy cows to dietary
restriction and rbST treatment.” 2008. Masters Thesis, University of Pretoria. Accessed January 16, 2021.
http://hdl.handle.net/2263/28939.
MLA Handbook (7th Edition):
Basson, Annelie. “Circulating
glucose responses in early lactation dairy cows to dietary
restriction and rbST treatment.” 2008. Web. 16 Jan 2021.
Vancouver:
Basson A. Circulating
glucose responses in early lactation dairy cows to dietary
restriction and rbST treatment. [Internet] [Masters thesis]. University of Pretoria; 2008. [cited 2021 Jan 16].
Available from: http://hdl.handle.net/2263/28939.
Council of Science Editors:
Basson A. Circulating
glucose responses in early lactation dairy cows to dietary
restriction and rbST treatment. [Masters Thesis]. University of Pretoria; 2008. Available from: http://hdl.handle.net/2263/28939
14.
Elias, Alexander.
Maternal Nutrient Restriction in Pregnant Guinea Pigs Impacts Fetal-Placental Growth and Oxygenation.
Degree: 2015, University of Western Ontario
URL: https://ir.lib.uwo.ca/etd/3061
► Maternal nutrient restriction (MNR) in guinea pigs results in placental structural abnormalities that reduce nutrient transport contributing to fetal growth restriction (FGR). However, whether fetal…
(more)
▼ Maternal nutrient restriction (MNR) in guinea pigs results in placental structural abnormalities that reduce nutrient transport contributing to fetal growth restriction (FGR). However, whether fetal oxygenation is also reduced as a further mediator of altered growth and development remains unknown. Guinea pig sows were fed ad libitum (Controls) or 70% of the control diet pre-pregnant switching to 90% at mid-pregnancy (MNR). Animals were necropsied near term for fetal-placental growth measures, blood metabolites, and markers of tissue hypoxia and oxidative stress. MNR resulted in FGR with brains that are large and livers that are small relative to body weight which suggests a degree of blood flow redistribution. FGR-MNR fetuses showed increased levels of hypoxia related markers in a tissue and sex specific manner, and decreased makers of oxidative stress. Together these results implicate hypoxia as a mechanism for aberrant growth and development and evidence for protective adaptations with MNR induced FGR.
Subjects/Keywords: Maternal Nutrient Restriction (MNR); Fetal Growth Restriction (FGR); Hypoxia; Oxidative stress; Fetal Programming; Undernutrition; Developmental Biology
…CHAPTER 5 - MATERNAL NUTRIENT RESTRICTION IN GUINEA PIGS ALTERS
OXIDATIVE STRESS AND AN… …Intrauterine growth restriction
M
Molar
MDA
Malondialdehyde
MNR
Maternal nutrient restriction… …MNR-FGR
Maternal nutrient restriction- fetal growth restriction cohort
MPR
Maternal… …changes in the placenta over the fetus, and maternal
nutrient restriction (MNR)… …changes
(Vonnahme 2003). Studies of moderate nutrient restriction, usually involving…
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Elias, A. (2015). Maternal Nutrient Restriction in Pregnant Guinea Pigs Impacts Fetal-Placental Growth and Oxygenation. (Thesis). University of Western Ontario. Retrieved from https://ir.lib.uwo.ca/etd/3061
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Elias, Alexander. “Maternal Nutrient Restriction in Pregnant Guinea Pigs Impacts Fetal-Placental Growth and Oxygenation.” 2015. Thesis, University of Western Ontario. Accessed January 16, 2021.
https://ir.lib.uwo.ca/etd/3061.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Elias, Alexander. “Maternal Nutrient Restriction in Pregnant Guinea Pigs Impacts Fetal-Placental Growth and Oxygenation.” 2015. Web. 16 Jan 2021.
Vancouver:
Elias A. Maternal Nutrient Restriction in Pregnant Guinea Pigs Impacts Fetal-Placental Growth and Oxygenation. [Internet] [Thesis]. University of Western Ontario; 2015. [cited 2021 Jan 16].
Available from: https://ir.lib.uwo.ca/etd/3061.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Elias A. Maternal Nutrient Restriction in Pregnant Guinea Pigs Impacts Fetal-Placental Growth and Oxygenation. [Thesis]. University of Western Ontario; 2015. Available from: https://ir.lib.uwo.ca/etd/3061
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
15.
LeMaster, Christopher.
THE EFFECTS OF LATE GESTATION MATERNAL NUTRIENT RESTRICTION WITH OR WITHOUT PROTEIN SUPPLEMENTATION IN ENDOCRINE REGULATION OF NEWBORN AND POSTNATAL BEEF CALVES.
Degree: MS, Animal and Veterinary Sciences, 2015, Clemson University
URL: https://tigerprints.clemson.edu/all_theses/2234
► A study was conducted to evaluate late gestation maternal nutrient restriction with or without protein supplementation on endocrine regulation in newborn beef calves. This study…
(more)
▼ A study was conducted to evaluate late gestation maternal
nutrient restriction with or without protein supplementation on endocrine regulation in newborn beef calves. This study utilized multiparous cows (4 and 5 yr of age, n = 57) randomly assigned to one of three treatments for the last 100 d of gestation. The control (n = 19) cows were fed to increase BCS while the
nutrient restricted (NR, n = 19) and
nutrient restricted with protein supplement (NRS, n = 19) cows were fed to lose 1.2 ± 0.2 BCS during the last 100 d of gestation. Control cows were allowed ad libitum access to tall fescue/crabgrass paddock and when grazing became insufficient, ad libitum hay was provided along with 1.3 kg of corn gluten feed 5 d/wk. Tall fescue paddocks were strip grazed to limit forage availability for NR and NRS. The NRS treatment were individually penned and fed 0.45 kg of soybean meal 3 d/wk. As forage became dormant the
nutrient restricted paddocks received limited fescue hay. After parturition cow/calf pairs were moved to one common pasture and received ad libitum silage and 1.8 kg of high concentrate feed. Maternal
nutrient restriction regardless of supplementation reduced cow plasma glucose and insulin concentrations during late gestation (P < 0.0001 and P = 0.0051 respectively). Calves from NR dams weighed less at parturition and the NRS calves were intermediate to control calves (33.4 ± 1.2, 35.0 ± 1.3 and 37.2 ± 1.3 kg respectively; P = 0.04,). Plasma glucose concentrations of unsuckled calves at parturition was reduced (P = 0.037) in NR and NRS calves compared to control (67.7 ± 6.5, 60.1 ± 6.9 and 83.7 ± 6.1 mg/dl respectively). At parturition, control and NRS calves had increased (P = 0.0037) plasma leptin concentrations compared to NR calves while calf plasma cortisol concentrations were greater for the
nutrient restricted groups than the control (trt x day P = 0.0135). This research demonstrates that late gestation
nutrient restriction reduces postnatal calf birth weight, plasma glucose and leads to reduced plasma leptin. Maternal protein supplementation appears to alleviate effects of late gestation
nutrient restriction. This research demonstrates that maternal protein supplementation during late gestation
nutrient restriction may alleviate effects of late gestation
nutrient restriction.
Advisors/Committee Members: Long, Nathan M, Andrae, John G, Higdon, III, H. Lee, Pratt, Scott L.
Subjects/Keywords: Calf Cortisol; Calf Leptin; Fetal Programming; Late Gestation; Nutrient Restriction; Protein Supplementation
…characteristics even during times of
nutrient restriction.
An objective of this work presented herein… …late gestation nutrient restriction on
maternal and calf performance. This study also… …demonstrated the effects of maternal
protein supplementation and nutrient restriction on newborn calf… …animal models. Periods of
nutrient restriction are very common to the beef industry. This can… …a loss of BW and BCS during periods of nutrient restriction (Vizcarra et
al., 1998…
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
LeMaster, C. (2015). THE EFFECTS OF LATE GESTATION MATERNAL NUTRIENT RESTRICTION WITH OR WITHOUT PROTEIN SUPPLEMENTATION IN ENDOCRINE REGULATION OF NEWBORN AND POSTNATAL BEEF CALVES. (Masters Thesis). Clemson University. Retrieved from https://tigerprints.clemson.edu/all_theses/2234
Chicago Manual of Style (16th Edition):
LeMaster, Christopher. “THE EFFECTS OF LATE GESTATION MATERNAL NUTRIENT RESTRICTION WITH OR WITHOUT PROTEIN SUPPLEMENTATION IN ENDOCRINE REGULATION OF NEWBORN AND POSTNATAL BEEF CALVES.” 2015. Masters Thesis, Clemson University. Accessed January 16, 2021.
https://tigerprints.clemson.edu/all_theses/2234.
MLA Handbook (7th Edition):
LeMaster, Christopher. “THE EFFECTS OF LATE GESTATION MATERNAL NUTRIENT RESTRICTION WITH OR WITHOUT PROTEIN SUPPLEMENTATION IN ENDOCRINE REGULATION OF NEWBORN AND POSTNATAL BEEF CALVES.” 2015. Web. 16 Jan 2021.
Vancouver:
LeMaster C. THE EFFECTS OF LATE GESTATION MATERNAL NUTRIENT RESTRICTION WITH OR WITHOUT PROTEIN SUPPLEMENTATION IN ENDOCRINE REGULATION OF NEWBORN AND POSTNATAL BEEF CALVES. [Internet] [Masters thesis]. Clemson University; 2015. [cited 2021 Jan 16].
Available from: https://tigerprints.clemson.edu/all_theses/2234.
Council of Science Editors:
LeMaster C. THE EFFECTS OF LATE GESTATION MATERNAL NUTRIENT RESTRICTION WITH OR WITHOUT PROTEIN SUPPLEMENTATION IN ENDOCRINE REGULATION OF NEWBORN AND POSTNATAL BEEF CALVES. [Masters Thesis]. Clemson University; 2015. Available from: https://tigerprints.clemson.edu/all_theses/2234

University of Illinois – Urbana-Champaign
16.
Chang, Yu-Rui.
Bacterial community composition in stream biofilms is influenced by algal response to varying light and phosphorus ratios.
Degree: MS, 0190, 2010, University of Illinois – Urbana-Champaign
URL: http://hdl.handle.net/2142/15997
► Strong correlations between bacterial communities and algal seasonal succession have been previously observed. In aquatic systems, dissolved organic carbon derived by algae is an important…
(more)
▼ Strong correlations between bacterial communities and algal seasonal succession have been previously observed. In aquatic systems, dissolved organic carbon derived by algae is an important resource for bacteria. Light and phosphorus availability are two factors that influence biomass and abundance of algae, and the changes will be reflected in the bacterial portion of the microbial community. Glycolate is an algal-specific exudate produced under excess light conditions. Glycolate uptake by bacteria has been shown to correlate with algal primary productivity. Bacterial populations that utilize glycolate possess the gene, glycolate oxidase subunit D (glcD). This gene was used as a marker to identify changes in specific bacterial populations that respond to algal exudates. In this study, development of periphyton biofilms in an experimental stream system was monitored across different light and phosphorus levels. Samples were collected every two days for community and chemistry analyses. Bacterial communities were monitored using DNA fingerprinting techniques based on ribosomal RNA genes and the glcD gene. We demonstrated that bacterial community composition changed significantly over the course of biofilm development, and light and phosphorus availability contributed to those differences in community composition. Our results suggest that a strong coupling between carbon flow and bacterial community composition. These results increase our understanding of the ecological drivers that impact benthic biofilm communities that carry out transformation of nutrients in streams.
Advisors/Committee Members: Kent, Angela D. (advisor).
Subjects/Keywords: biofilm; periphyton; light and nutrient hypothesis; light and phosphorus ratio; algal exudate; glycolate; glycolate oxidase; glcD gene; microbial community; automated ribosomal intergenic spacer analysis (ARISA); Terminal Restriction Fragment Length Polymorphism (T-RFLP); 16S ribosomal RNA gene
Record Details
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Share »
Record Details
Similar Records
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Chang, Y. (2010). Bacterial community composition in stream biofilms is influenced by algal response to varying light and phosphorus ratios. (Thesis). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/15997
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Chang, Yu-Rui. “Bacterial community composition in stream biofilms is influenced by algal response to varying light and phosphorus ratios.” 2010. Thesis, University of Illinois – Urbana-Champaign. Accessed January 16, 2021.
http://hdl.handle.net/2142/15997.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Chang, Yu-Rui. “Bacterial community composition in stream biofilms is influenced by algal response to varying light and phosphorus ratios.” 2010. Web. 16 Jan 2021.
Vancouver:
Chang Y. Bacterial community composition in stream biofilms is influenced by algal response to varying light and phosphorus ratios. [Internet] [Thesis]. University of Illinois – Urbana-Champaign; 2010. [cited 2021 Jan 16].
Available from: http://hdl.handle.net/2142/15997.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Chang Y. Bacterial community composition in stream biofilms is influenced by algal response to varying light and phosphorus ratios. [Thesis]. University of Illinois – Urbana-Champaign; 2010. Available from: http://hdl.handle.net/2142/15997
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
.