subject:(mistura enantiom trica R75 S25 de bupivaca na)

Universitat Autònoma de Barcelona

1. García Padilla, Esteban. Validación del delta base déficit en pacientes traumáticos.

Degree: Departament de Cirurgia, 2015, Universitat Autònoma de Barcelona

► Summary: The BISS its a survival probability model proven in netherland, it shows to be objective; Our study goal is to validate the BISS in… (more)

▼ Summary: The BISS its a survival probability model proven in netherland, it shows to be objective; Our study goal is to validate the BISS in our patients. We performed a epidemiological, observational, descriptive and prospective study including the patients admitted as a poli-traumatic code in our hospital, the data was collected between November 2008 and March 2014. We start calculating the main anatomical and physiological scales, base deficit delta and survival probability models. Later we compare the base deficit delta between those who survived and those who didn't, correlating that value with the scales and the survival probability models. Finally we measure the area under the curve (AUC) of BISS and TRISS ROC curves comparing them. The study includes 467 patients with a medium ISS of 17,55. The base deficit delta was significantly superior in the group who didn't survive and it correlates significantly with the mortality. As well a high base deficit delta correlates with a low RTS, a high ISS and a low survival probability. In order to validate the BISS we use only 238 patients who had all available values required to calculate the two survival probability models, BISS and TRISS. In front of the suspicious of the differences among the populations, we calculate a new coefficients for the BISS using logistic regression. For each new coefficient we calculate a new confidence interval (CI 0,95) assuming equally if this interval includes the original model coefficient. Obtaining the AUC of the BISS ROC curve greater than the TRISS (0,946 Vs 0,932). Once we compare the two models we found no differences between them, validating the BISS in our patients. The main limitation in our study has been the lost of data in the sample. We calculate the TRISS to the 73.44% and the BISS to the 58,52% of the sample. A lost of 124 patients for the TRISS and 147 patients for the BISS calculation was obtained, that means a increase of 4,29% for the TRISS sample. The BISS, being a objective valuation allows the consecution of a most realistic survival probability result. Its application in all hospitals would allow the comparison between results of the institutions, comparing mortality, survival, injury gravity and the quality of the instituted programs, widening the security margin in the attention of those patients. Advisors/Committee Members: [email protected] (authoremail), true (authoremailshow), Rius Cornadó, X. (Xavier) (director), Cañellas Arsegol, Montserrat (director), true (authorsendemail).

Subjects/Keywords: Exces de bases; Exess de basse; Probabilitat supervivència; Probabilidad supervivencia; Ciències de la Salut; 61

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APA (6^th Edition):

García Padilla, E. (2015). Validación del delta base déficit en pacientes traumáticos. (Thesis). Universitat Autònoma de Barcelona. Retrieved from http://hdl.handle.net/10803/298179

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

García Padilla, Esteban. “Validación del delta base déficit en pacientes traumáticos.” 2015. Thesis, Universitat Autònoma de Barcelona. Accessed December 08, 2019. http://hdl.handle.net/10803/298179.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

García Padilla, Esteban. “Validación del delta base déficit en pacientes traumáticos.” 2015. Web. 08 Dec 2019.

Vancouver:

García Padilla E. Validación del delta base déficit en pacientes traumáticos. [Internet] [Thesis]. Universitat Autònoma de Barcelona; 2015. [cited 2019 Dec 08]. Available from: http://hdl.handle.net/10803/298179.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

García Padilla E. Validación del delta base déficit en pacientes traumáticos. [Thesis]. Universitat Autònoma de Barcelona; 2015. Available from: http://hdl.handle.net/10803/298179

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universitat Autònoma de Barcelona

2. Gómez Lanza, Esther. Análisis de la concentración sérica de vitamina D como factor de riesgo de cáncer de próstata y agresividad tumoral.

Degree: Departament de Cirurgia, 2010, Universitat Autònoma de Barcelona

URL: http://hdl.handle.net/10803/32079

► Prostate cancer is a frequent malignant tumour. The incidence is higher than years ago. The etiology is unknown but there are risk factors for prostatic… (more)

Subjects/Keywords: Ciències de la Salut; 611

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APA (6^th Edition):

Gómez Lanza, E. (2010). Análisis de la concentración sérica de vitamina D como factor de riesgo de cáncer de próstata y agresividad tumoral. (Thesis). Universitat Autònoma de Barcelona. Retrieved from http://hdl.handle.net/10803/32079

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Gómez Lanza, Esther. “Análisis de la concentración sérica de vitamina D como factor de riesgo de cáncer de próstata y agresividad tumoral.” 2010. Thesis, Universitat Autònoma de Barcelona. Accessed December 08, 2019. http://hdl.handle.net/10803/32079.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Gómez Lanza, Esther. “Análisis de la concentración sérica de vitamina D como factor de riesgo de cáncer de próstata y agresividad tumoral.” 2010. Web. 08 Dec 2019.

Vancouver:

Gómez Lanza E. Análisis de la concentración sérica de vitamina D como factor de riesgo de cáncer de próstata y agresividad tumoral. [Internet] [Thesis]. Universitat Autònoma de Barcelona; 2010. [cited 2019 Dec 08]. Available from: http://hdl.handle.net/10803/32079.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Gómez Lanza E. Análisis de la concentración sérica de vitamina D como factor de riesgo de cáncer de próstata y agresividad tumoral. [Thesis]. Universitat Autònoma de Barcelona; 2010. Available from: http://hdl.handle.net/10803/32079

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universitat Autònoma de Barcelona

3. Mesa Marrero, Carmen Margarita. Función vestibular en la mutación A1555G del ADN mitocondrial.

Degree: Departament de Cirurgia, 2015, Universitat Autònoma de Barcelona

URL: http://hdl.handle.net/10803/378346

► Objectives/Hypothesis: To evaluate vestibular function in patients with 1555 A to G mutation in the 12S ribosomal RNA gene Study design: It’s an observational cross-sectional… (more)

▼ Objectives/Hypothesis: To evaluate vestibular function in patients with 1555 A to G mutation in the 12S ribosomal RNA gene Study design: It’s an observational cross-sectional study. Material and Method: Thirty-four patients carrying the mitochondrial A1555G DNA mutation from thirteen unrelated families were enrolled. Clinical histories especially aminoglycosides exposure and the audiological and vestibular symptoms were recorded. Audiological evaluation with pure tone audiograms was performed. Vestibular examinations including caloric testing and cervical vestibular evoked myogenic potentials (VEMPc) in response to air-conducted sound were used as measures of canalicular and saccular function, respectively. Results: Ten patients had vestibular symptoms. Twenty-two patients presented hearing loss and thirteen subjects had received aminoglycosides. The auditory defect was a bilateral symmetrical sensorineural hearing loss affecting mainly the high tones. The presence of deafness and its severity was significantly correlated with the aminoglycoside exposure. Aminoglycosides increase 5 times the risk of developing profound hearing loss or cofosis. Therefore, twenty-two of the 34 patients showed abnormal caloric responses. The caloric deficiency was bilateral canal paresis in 20 cases and unilateral hipofunction in two cases. Aminoglycoside treatment history, hearing impairment and its severity are not significantly correlated with the abnormal canal response. On the other hand, eleven patients had abnormal VEMPc: nine showed low amplitude (6 cases bilaterally and 3 unilaterally) and six patients had an asymmetric amplitude. None had absence of the VEMPs response or abnormal latencies. Aminoglycoside administration and the degree of hearing loss are not correlated with the pathologic VEMPc, but an abnormal VEMPc response is significantly associated with hearing loss. Global dysfunction, saccular and canalicular, increase 4 times the risk of developing deafness not related to hearing loss degree. Conclusions: The findings suggest that the A1555G mutation can cause vestibular dysfunction involving both the superior and inferior vestibular nerve systems, especially canalicular dysfunction. It looks like aminoglycoside might not be a causal factor for vestibular impairment in patients carrying this mutation. Furthermore, our overall results of pathological vestibular tests suggest that there is a relationship between hearing loss and vestibular dysfunction. Advisors/Committee Members: [email protected] (authoremail), true (authoremailshow), García Arumí, Ana Mª (director), Quesada Marín, Pedro (director), true (authorsendemail).

Subjects/Keywords: Ciències de la Salut; 616.2

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APA (6^th Edition):

Mesa Marrero, C. M. (2015). Función vestibular en la mutación A1555G del ADN mitocondrial. (Thesis). Universitat Autònoma de Barcelona. Retrieved from http://hdl.handle.net/10803/378346

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Mesa Marrero, Carmen Margarita. “Función vestibular en la mutación A1555G del ADN mitocondrial.” 2015. Thesis, Universitat Autònoma de Barcelona. Accessed December 08, 2019. http://hdl.handle.net/10803/378346.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Mesa Marrero, Carmen Margarita. “Función vestibular en la mutación A1555G del ADN mitocondrial.” 2015. Web. 08 Dec 2019.

Vancouver:

Mesa Marrero CM. Función vestibular en la mutación A1555G del ADN mitocondrial. [Internet] [Thesis]. Universitat Autònoma de Barcelona; 2015. [cited 2019 Dec 08]. Available from: http://hdl.handle.net/10803/378346.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Mesa Marrero CM. Función vestibular en la mutación A1555G del ADN mitocondrial. [Thesis]. Universitat Autònoma de Barcelona; 2015. Available from: http://hdl.handle.net/10803/378346

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universitat Autònoma de Barcelona

4. Garcia Vera, Wilber Calixto. Optimización de los protocolos de crioconservación de semen ovino de las razas autóctonas en peligro de extinción xisqueta y aranesa.

Degree: Departament de Cirurgia, 2014, Universitat Autònoma de Barcelona

URL: http://hdl.handle.net/10803/284242

► In order to optimize ram semen preservation of Xisqueta and Aranesa breeds, we studied alternatives to the fresh egg yolk in extender making to reduce… (more)

▼ In order to optimize ram semen preservation of Xisqueta and Aranesa breeds, we studied alternatives to the fresh egg yolk in extender making to reduce heterogeneity, microbiology pollution and some components that interfere negatively in its cryoprotection capability, analyzing different types of egg yolk (fresh, powdered and clarified). Simultaneously, seminal plasma removal previous to cryopreservation and donor age were tested. Secondly, our aim was to obtain an extender free of animal origin cryoprotectants with a clearly-defined composition, therefore the efficiency of the soy lecithin or butylhydroxytoluene (BHT), combined with glycerol or trehalose were assessed. Moreover, the effect of two buffer systems, TRIS vs TEST, and the addition of BHT as antioxidant on sperm cryosurvival was analyzed. Optimal concentration of BHT and the presence of seminal plasma in the extender were also studied. Finally, donor age and photoperiod as the application of melatonin implants on rams in spring, the addition of antioxidants (BHT vs melatonin) in the extender and individual effect on sperm cryopreservation were evaluated. Therefore, semen from 8 rams (4 of each breed from 1 to 2.5 years old approximately) were collected, doing a total of 6 replicas/experiment. Briefly, after semen collection, mass motility and volume were assessed. Then ejaculates were pooled and split in the required aliquots in each experiment, except when semen was preserved individually. For seminal plasma removal, pooled semen was centrifuged twice (at 600 g for 10 minutes) and the sediment was resuspended in the corresponding media at a final concentration of 400 x106 of sperm/mL. The different sperm samples were refrigerated at 5ºC during 4h, packaged in straws of 0.25 mL, freezed in nitrogen vapors and immerged in it, until the samples were thawed (30'' at 37ºC). Viability, morphology and osmotic resistance of fresh and refrigerated sperm samples were tested by eosine-nigrosine stain and hypoosmotic swelling test (HOST). The kinetic parameters after the refrigeration and thawing were analyzed by ISAS® system as sperm morphometry, following the trade protocol Diff-Quik. Integrity of sperm membranes and mitochondrial activity after the thawing were evaluate using a quadruple fluorescent stain (SYBR14, propidium iodide, Arachis hipogea lecithin labeled with phycoerithin and Mitotracker deep red) with a flow cytometer. Our results showed that powdered egg yolk can be used satisfactorily on refrigeration and cryopreservation of ram semen, obtaining a better cryoprotectant capability when is combined with glycerol and TRIS buffer system. On the other hand, seminal plasma removal by centrifugation improved sperm cryosurvival, although its presence in the extender does not affect negatively sperm quality. Generally, the supplementation of BHT (5.0mM) improved the quality of preserved sperms, regardless of semen washing, donor age or photoperiod, meanwhile the use of melatonin as antioxidant in the media does not. Neither the use of melatonin implants… Advisors/Committee Members: [email protected] (authoremail), true (authoremailshow), Palomo Peiró, María Jesús (director), true (authorsendemail).

Subjects/Keywords: Ciències de la Salut; 636

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APA (6^th Edition):

Garcia Vera, W. C. (2014). Optimización de los protocolos de crioconservación de semen ovino de las razas autóctonas en peligro de extinción xisqueta y aranesa. (Thesis). Universitat Autònoma de Barcelona. Retrieved from http://hdl.handle.net/10803/284242

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Garcia Vera, Wilber Calixto. “Optimización de los protocolos de crioconservación de semen ovino de las razas autóctonas en peligro de extinción xisqueta y aranesa.” 2014. Thesis, Universitat Autònoma de Barcelona. Accessed December 08, 2019. http://hdl.handle.net/10803/284242.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Garcia Vera, Wilber Calixto. “Optimización de los protocolos de crioconservación de semen ovino de las razas autóctonas en peligro de extinción xisqueta y aranesa.” 2014. Web. 08 Dec 2019.

Vancouver:

Garcia Vera WC. Optimización de los protocolos de crioconservación de semen ovino de las razas autóctonas en peligro de extinción xisqueta y aranesa. [Internet] [Thesis]. Universitat Autònoma de Barcelona; 2014. [cited 2019 Dec 08]. Available from: http://hdl.handle.net/10803/284242.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Garcia Vera WC. Optimización de los protocolos de crioconservación de semen ovino de las razas autóctonas en peligro de extinción xisqueta y aranesa. [Thesis]. Universitat Autònoma de Barcelona; 2014. Available from: http://hdl.handle.net/10803/284242

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universitat Autònoma de Barcelona

5. Otero Piñeiro, Ana María. Utilidad de la angiografía mediante verde de indocianina para la prevención del fallo de sutura en cirugía colorrectal.

Degree: Departament de Cirurgia, 2018, Universitat Autònoma de Barcelona

URL: http://hdl.handle.net/10803/664125

► Aims: Anastomotic leak (AL) is the most feared complication in colorectal surgery. Indocyanine Green (ICG) fluorescence angiography allows for a real-time intraoperative evaluation of bowel… (more)

▼ Aims: Anastomotic leak (AL) is the most feared complication in colorectal surgery. Indocyanine Green (ICG) fluorescence angiography allows for a real-time intraoperative evaluation of bowel perfusion and is considered as a promising tool to reduce AL. Based on this fact, we have carried out this study in which we want to demonstrate that the use of indocyanine green angiography (ICGA) decreases the frequency of anastomotic leak in colorectal surgery performed by TaTME (transanal total mesorectal excision) by allowing to choose the optimal place for performing it. Methods: Comparative non-randomized prospective validation study between surgery with ICGA and standard surgery (surgery without ICGA), determining the effect on anastomotic leak in patients undergoing an Anterior Resection + TaTME for rectal cancer. ICGA was used in 50 patients with rectal cancer undergoing anterior resection using TaTME with subsequent colorectal or coloanal anastomosis. The results were compared with a control group of 204 patients previously operated by the same surgeon and surgical team, without the use of ICGA. The data was collected prospectively. Results: A total of 254 patients were included in the analysis, 50 (19.7%) in the ICG group and 204 (80.3%) in the non-ICG group. Both groups did not differ in male-female ratio, median age, obesity, nor smoking rate. The majority of the patients were classified as ASA II. 137 patients (50.2% vs. 46.0%; p=0.760) underwent neoadjuvant chemoradiotherapy. Mean anastomotic height was 4.85 cm vs. 4,68 cm (p=0.985), splenic flexure mobilization was performed in 91 patients (34.3% vs. 42.0%; p=0.327), while a diverting stoma was constructed in 186 patients (72.1% vs. 78.0%; p=0.477). ICGA led to a change in the resection margin in 16 patients (32.0%) and to mobilization of the splenic flexure after anastomosis construction in 1 (2.0%) patient. AL was diagnosed in 1 patient (2.0%) in the ICG group and in 23 patients (11.3%) in the non-ICG group (p=0.056). Postoperative intraabdominal collection was diagnosed in 17 patients (7.4% vs. 6.0%; p=0.692), and reintervention was needed in 24 patients (10.8% vs. 4.0%; p=0.182). The median length of hospital stay was 5.8 days (6.0 vs. 5.0; p=0.037). Conclusion: This study demonstrates the feasibility and safety of the Fluorescence angiography using indocyanine green in rectal cancer surgery using a transanal approach (TaTME). In addition, based on our results, we can say that the use of ICGA can change the margin of proximal resection in a considerable number of patients during the practice of TaTME, which could reduce the incidence of AL in these high-risk patients. Even so, the fact of presenting 1 AL in the ICGA group makes us think that the ICGA methodology could be improved, perhaps with a quantitative rather than a qualitative fluorescence evaluation. Advisors/Committee Members: [email protected] (authoremail), true (authoremailshow), Balibrea del Castillo, Jose María (director), Lacy Fortuny, Antonio Ma. de (codirector).

Subjects/Keywords: Verd d'indocianina; Verde de indocianina; Indocyanine green; Càncer de recte; Cáncer de recto; Rectal cancer; TaTME; Ciències de la Salut; 617

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APA (6^th Edition):

Otero Piñeiro, A. M. (2018). Utilidad de la angiografía mediante verde de indocianina para la prevención del fallo de sutura en cirugía colorrectal. (Thesis). Universitat Autònoma de Barcelona. Retrieved from http://hdl.handle.net/10803/664125

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Otero Piñeiro, Ana María. “Utilidad de la angiografía mediante verde de indocianina para la prevención del fallo de sutura en cirugía colorrectal.” 2018. Thesis, Universitat Autònoma de Barcelona. Accessed December 08, 2019. http://hdl.handle.net/10803/664125.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Otero Piñeiro, Ana María. “Utilidad de la angiografía mediante verde de indocianina para la prevención del fallo de sutura en cirugía colorrectal.” 2018. Web. 08 Dec 2019.

Vancouver:

Otero Piñeiro AM. Utilidad de la angiografía mediante verde de indocianina para la prevención del fallo de sutura en cirugía colorrectal. [Internet] [Thesis]. Universitat Autònoma de Barcelona; 2018. [cited 2019 Dec 08]. Available from: http://hdl.handle.net/10803/664125.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Otero Piñeiro AM. Utilidad de la angiografía mediante verde de indocianina para la prevención del fallo de sutura en cirugía colorrectal. [Thesis]. Universitat Autònoma de Barcelona; 2018. Available from: http://hdl.handle.net/10803/664125

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universitat Autònoma de Barcelona

6. Vial Gallardo, Manuel F. Prevalencia de la enfermedad por reflujo gastroesofágico en población adulta.

Degree: Departament de Cirurgia, 2009, Universitat Autònoma de Barcelona

URL: http://hdl.handle.net/10803/4332

► Title. Prevalence of gastroesophageal reflux disease in adults. Introduction. Gastroesophageal reflux disease (GERD) is a frequent cause of medical consultation, although prevalence studies are scarce… (more)

▼ Title. Prevalence of gastroesophageal reflux disease in adults. Introduction. Gastroesophageal reflux disease (GERD) is a frequent cause of medical consultation, although prevalence studies are scarce and in most cases performed without previously validated scales. Furthermore, it has been described in several studies that GERD affects negatively the quality of life (QoL) of patients in a manner similar to other diseases such as coronary heart disease. On the other hand, information about mental health disorders (MHD) in this population is also scarce. Aim. To estimate the prevalence of GERD and its association with the QoL and the prevalence of MHD in the adult population assisted by the Hospital del Mar. Patients and methods. Cross-sectional study design. We included patients older than 18 years visited in primary care centers in the districts of Ciutat Vella and Sant Mart' of Barcelona, which were selected through a random cluster sampling. The patients answered the following validated questionnaires to the Spanish language: GERD questionnaire for the diagnosis of GERD; SF-36 questionnaire for assessing general QoL and GHQ-28 questionnaire for determining MHD. The calculation of sample size was obtained from an estimated prevalence of 30%, a confidence of 95% and an accuracy of 4%, given 504 subjects to interview. We used descriptive statistics and bivariate and multivariate analysis to establish the association between GERD, QoL and MHD. Results. 514 patients were interviewed (64.2% female, mean age 60.4 ± 17.7 years). The prevalence of GERD was 32.9%. Patients with GERD had worse scores on all scales of SF-36 (p <0.001) and had a higher prevalence of MHD (23.8% vs 50.9%, p <0.001). In multivariate analysis, GERD was associated with the use of gastric protectors (GP), the district, the QoL and the presence of MHD. Conclusions. GERD affects a third of the sample studied, and is associated independently with the district, the use of GP, the QoL and the presence of MHD. Advisors/Committee Members: [email protected] (authoremail), true (authoremailshow), Grande Posa, Luis (director).

Subjects/Keywords: Salud mental; Calidad de vida; Prevalencia; Ciències de la Salut; 616.3

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APA (6^th Edition):

Vial Gallardo, M. F. (2009). Prevalencia de la enfermedad por reflujo gastroesofágico en población adulta. (Thesis). Universitat Autònoma de Barcelona. Retrieved from http://hdl.handle.net/10803/4332

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Vial Gallardo, Manuel F. “Prevalencia de la enfermedad por reflujo gastroesofágico en población adulta.” 2009. Thesis, Universitat Autònoma de Barcelona. Accessed December 08, 2019. http://hdl.handle.net/10803/4332.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Vial Gallardo, Manuel F. “Prevalencia de la enfermedad por reflujo gastroesofágico en población adulta.” 2009. Web. 08 Dec 2019.

Vancouver:

Vial Gallardo MF. Prevalencia de la enfermedad por reflujo gastroesofágico en población adulta. [Internet] [Thesis]. Universitat Autònoma de Barcelona; 2009. [cited 2019 Dec 08]. Available from: http://hdl.handle.net/10803/4332.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Vial Gallardo MF. Prevalencia de la enfermedad por reflujo gastroesofágico en población adulta. [Thesis]. Universitat Autònoma de Barcelona; 2009. Available from: http://hdl.handle.net/10803/4332

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universitat Autònoma de Barcelona

7. Pidemunt Moli, Gemma. Factores determinantes en el deterioro de la función y la calidad de vida del anciano afecto de fractura de cadera.

Degree: Departament de Cirurgia, 2010, Universitat Autònoma de Barcelona

URL: http://hdl.handle.net/10803/4352

► Introduction: Hip fracture is the most important consequence of osteoporosi due to its high mortality rate one year after and the functional impairments that patients… (more)

▼ Introduction: Hip fracture is the most important consequence of osteoporosi due to its high mortality rate one year after and the functional impairments that patients have. Despite the improvements in surgical technique, functional outcome of these patients in cases is not correlated with radiologic results.We have also to take into account the elevated costs (social and economycal) that this kind of fracture causes, for this reason, it is important for sanitary professionals to know how this fracture affects quality of life patients and the ability to perform the daily living activities. Moreover, it is interesting to know wich characteristics of the fracture, patient or social network will affect the final outcome.Only this way, we will be able to inform our patients and relatives about the illness they are suffering. Patient and method: We performed a prospective, longitudinal, obervational study including 126 consecutive patients older than 65 years suffering hip fracture.Patients with cognitive impairment (Folstein test), previous contralateral fracture or pathologic fracture due to neoplasia were excluded. The follow up was 1 year, losing 6,3% patients and having a mortality rate at year of 14,2% The targets evaluated were:epidemiologic data, cognitive status (Folstein test), level of dependence (Barthel index),mood disorders (GDS-15),morbidity (Charlson index)and quality of life (SF-36) Results: Our population has similar epidemiological characteristics than most of published literature series , being a more frequent fracture in women older than 80 years.Most of our patients came to hospital from their own houses and had a general health status similar to general population of same age and sex. Their quality of life gets worse at 3 months after the fracture, specially for physical skills, then improves at one year, but never achieves the pre-fracture level. Mortality is significatively correlated to number of comorbidities that patients have. Hip fracture worsens mood status, the more depressed patients are the worse quality of life and functional outcome they have. We have not found statistically significant correlation between functional outcome and type of fracture,type of treatment,or number of days before the surgery Discussion and conclusions: Quality of life and level of dependence clearly worsens three months after a hip fracture, then improve during the following months but never achieve the pre fracture level. Functional outcome and level of dependence have a positive correlation with perception of general health that patients have.In contrast, mood disorders have a negative correlations with functional results and quality of life. We can predict, based on mental state and quality of life that patients have in hospital revenue , wich patients will have poor functional results and will be more dependent , this will help to plan sanitary resources needed in each case. Key words: Hip fracture, quality of life, mood… Advisors/Committee Members: [email protected] (authoremail), true (authoremailshow), Cáceres Palou, Enrique (director).

Subjects/Keywords: Traumatologia; Calidad de vida; Ciències de la Salut; 616

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APA (6^th Edition):

Pidemunt Moli, G. (2010). Factores determinantes en el deterioro de la función y la calidad de vida del anciano afecto de fractura de cadera. (Thesis). Universitat Autònoma de Barcelona. Retrieved from http://hdl.handle.net/10803/4352

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Pidemunt Moli, Gemma. “Factores determinantes en el deterioro de la función y la calidad de vida del anciano afecto de fractura de cadera.” 2010. Thesis, Universitat Autònoma de Barcelona. Accessed December 08, 2019. http://hdl.handle.net/10803/4352.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Pidemunt Moli, Gemma. “Factores determinantes en el deterioro de la función y la calidad de vida del anciano afecto de fractura de cadera.” 2010. Web. 08 Dec 2019.

Vancouver:

Pidemunt Moli G. Factores determinantes en el deterioro de la función y la calidad de vida del anciano afecto de fractura de cadera. [Internet] [Thesis]. Universitat Autònoma de Barcelona; 2010. [cited 2019 Dec 08]. Available from: http://hdl.handle.net/10803/4352.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Pidemunt Moli G. Factores determinantes en el deterioro de la función y la calidad de vida del anciano afecto de fractura de cadera. [Thesis]. Universitat Autònoma de Barcelona; 2010. Available from: http://hdl.handle.net/10803/4352

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universitat Autònoma de Barcelona

8. Ojanguren Arranz, Amaia. El Lung Allocation Score como modelo predictivo de morbimortalidad en el trasplante pulmonar.

Degree: Departament de Cirurgia, 2011, Universitat Autònoma de Barcelona

URL: http://hdl.handle.net/10803/79136

► BACKGROUND: Lung transplantation has become a widely accepted treatment in the management of a broad spectrum of end stage pulmonary diseases. However, the number of… (more)

▼ BACKGROUND: Lung transplantation has become a widely accepted treatment in the management of a broad spectrum of end stage pulmonary diseases. However, the number of donor organs remains far less than the number of patients who may potentially benefit from this procedure. The development of the lung allocation system (LAS) in the United States in 2005 marked the first time an estimate of benefit was used to prioritize organ allocation. The LAS was designed to prioritize wait-list candidates based on a combination of wait-list urgency and post-transplant survival, whereas, the lung allocation policy in the majority of lung transplant programmes abroad is based on time accrued on the waiting list. OBJECTIVES: The purpose of this study was to examine if the LAS at the time of the lung transplantation would be a prognostic factor with regards to morbidity and mortality for the 170 patients who underwent a lung transplant between 2006-2009 in Vall d´Hebron Hospital, Barcelone (Spain). METHODS: All recipients aged > 12 years undergoing first-time lung transplantation during the period from January 1, 2006 to December 31, 2009 were included in the study. The cohort was divided into three groups: LAS < 32.5 (n=58, 37%), LAS 32.5-36 (n=50, 32%) and LAS > 36 (n=49, 31%), referred to as low LAS (LLAS), intermediate LAS (ILAS) and high LAS (HLAS). A time to event analysis was performed for risk of death after transplantation using Kaplan-Meier survival and Cox proportional hazard models. RESULTS: Patients in high risk group (LAS>36) had significantly worse first year survival compared with lower LAS recipients (67% vs. 83%; p=0.03 by log rank test). Patients with high risk group were also found to have increased risk of death (Hazard Ratio 1.99) compared with low risk group. HLAS recipients were more likely to require mechanical ventilatory support at the time of transplant compared with patients in the low-intermediate risk groups. Patients in the high risk group were also found to have increased airway complications. CONCLUSIONS: The lung allocation score is useful as a prognostic factor for the cohort of patients who underwent a lung transplant in the Vall d´Hebron Hospital. HLAS is associated with decreased one year survival and increased complications during the post-transplant hospitalization. Advisors/Committee Members: [email protected] (authoremail), true (authoremailshow), Solé Montserrat, Juan (director), Armengol Carrasco, Manuel (director), true (authorsendemail).

Subjects/Keywords: Trasplante pulmonar; Lista de espera; Score; Ciències de la Salut; 617

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Ojanguren Arranz, A. (2011). El Lung Allocation Score como modelo predictivo de morbimortalidad en el trasplante pulmonar. (Thesis). Universitat Autònoma de Barcelona. Retrieved from http://hdl.handle.net/10803/79136

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Ojanguren Arranz, Amaia. “El Lung Allocation Score como modelo predictivo de morbimortalidad en el trasplante pulmonar.” 2011. Thesis, Universitat Autònoma de Barcelona. Accessed December 08, 2019. http://hdl.handle.net/10803/79136.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Ojanguren Arranz, Amaia. “El Lung Allocation Score como modelo predictivo de morbimortalidad en el trasplante pulmonar.” 2011. Web. 08 Dec 2019.

Vancouver:

Ojanguren Arranz A. El Lung Allocation Score como modelo predictivo de morbimortalidad en el trasplante pulmonar. [Internet] [Thesis]. Universitat Autònoma de Barcelona; 2011. [cited 2019 Dec 08]. Available from: http://hdl.handle.net/10803/79136.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Ojanguren Arranz A. El Lung Allocation Score como modelo predictivo de morbimortalidad en el trasplante pulmonar. [Thesis]. Universitat Autònoma de Barcelona; 2011. Available from: http://hdl.handle.net/10803/79136

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universitat Autònoma de Barcelona

9. García Lorenzo, Jacinto. Valoración de un método de clasificación y estadiaje de la segunda neoplasia de cabeza y cuello.

Degree: Departament de Cirurgia, 2012, Universitat Autònoma de Barcelona

URL: http://hdl.handle.net/10803/96383

► Introduction Metacrhonous second primary tumors are amongst the main obstacles that hamper long term survival after a head and neck squamous cell carcinoma. When compared… (more)

▼ Introduction Metacrhonous second primary tumors are amongst the main obstacles that hamper long term survival after a head and neck squamous cell carcinoma. When compared with index tumors of the same stage and location, prognosis of second tumors is significantly worse. Medical literature remains controversial regarding the causes of this phenomenon, while some authors point to the use of certain treatment options for the index tumor as a plausible cause. Objectives We studied the prognostic influence of a metachronous tumor in the survival of a cohort of patients diagnosed of a squamous cell carcinomoa of the oral cavity, pharynx or larynx. Secondly, we evaluated the contribution of diverse variables related to the index tumor in the prognosis of the patient after diagnosis of the second neoplasm. Patients and Methods A retrospective review was carried out using the tumor database of the Otolaryngology Department of the Hospital de la Santa Creu i Sant Pau between 1985 and 2006. This database prospectively collects information regarding the localization, extension and treatment of all tumors diagnosed and treated in the department. The study sample was composed of 3676 patients diagnosed of a squamous cell carcinoma of the oral cavity, oro- or hypopharynx or larynx with a minimal follow-up of 12 months. In 301 cases a second primary tumor of the mentioned locations was found (8% of the total number of cases). Multivariate Cox analysis and classification tree algorithms (C5.0, C&RT, QUEST y CHAID) were used to assess prognostic factors. Results. Second primary tumors of the oral cavity, oropharynx, larynx or hypopharynx showed a 10% decrease in survival with respect to patients with a single tumor of such locations. Conventional uni and multivariate analysis failed to detect relevant prognostic index tumor-related factors. On the other hand, classification tree algorithms highlighted the relevance of index tumor extension and radiotherapy use as relevant predictors of survival after diagnosis of a second malignancy. This information has served as basis for the proposal of a second neoplasms prognostic classification system. Conclusions. Metachronous second neoplasms reduce the survival of patients suffering from head and neck carcinomas. Index tumor extension and the use of radiotherapy in the treatment of the index significantly affect survival of patients with a second malignancy. The nature of these relationships is complex and escapes traditional statistical methods. Advisors/Committee Members: [email protected] (authoremail), true (authoremailshow), Quer, Miquel (director), León i Vintró, Xavier (director), true (authorsendemail).

Subjects/Keywords: Cancer de cabeza y cuello; Segundos tumores; Mineria de datos; 616

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APA (6^th Edition):

García Lorenzo, J. (2012). Valoración de un método de clasificación y estadiaje de la segunda neoplasia de cabeza y cuello. (Thesis). Universitat Autònoma de Barcelona. Retrieved from http://hdl.handle.net/10803/96383

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

García Lorenzo, Jacinto. “Valoración de un método de clasificación y estadiaje de la segunda neoplasia de cabeza y cuello.” 2012. Thesis, Universitat Autònoma de Barcelona. Accessed December 08, 2019. http://hdl.handle.net/10803/96383.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

García Lorenzo, Jacinto. “Valoración de un método de clasificación y estadiaje de la segunda neoplasia de cabeza y cuello.” 2012. Web. 08 Dec 2019.

Vancouver:

García Lorenzo J. Valoración de un método de clasificación y estadiaje de la segunda neoplasia de cabeza y cuello. [Internet] [Thesis]. Universitat Autònoma de Barcelona; 2012. [cited 2019 Dec 08]. Available from: http://hdl.handle.net/10803/96383.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

García Lorenzo J. Valoración de un método de clasificación y estadiaje de la segunda neoplasia de cabeza y cuello. [Thesis]. Universitat Autònoma de Barcelona; 2012. Available from: http://hdl.handle.net/10803/96383

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universitat Autònoma de Barcelona

10. Martínez Cuenca, Esther. Alteraciones del metabolismo fosfocálcico y óseo en cáncer de próstata bajo supresión androgénica: Utilidad de los marcadores de recambio óseo para diagnóstico de osteoporosis.

Degree: Departament de Cirurgia, 2012, Universitat Autònoma de Barcelona

URL: http://hdl.handle.net/10803/363922

► Introduction: Prostate cancer is one of the three most common cancers in incidence and cause of death in developed countries. Androgen deprivation has been used… (more)

▼ Introduction: Prostate cancer is one of the three most common cancers in incidence and cause of death in developed countries. Androgen deprivation has been used to treat symptoms and reduce metastases. However this treatment also causes side effects such as low bone mineral density and as a result increases the risk of fractures. The aims are: to determine the prevalence of osteoporosis in patients with prostate cancer and androgen deprivation; to assess in these patients phosphocalcic metabolism by measurement of serum concentration of calcium, phosphorus, vitamin D3 and PTH, and urine concentration of calcium and phosphorus, depending on androgen deprivation and bone mineral density; to analyze the behaviour of bone turnover markers, total alkaline phosphatase, bone alkaline phosphatase and tartrate-resistant acid phosphatase in serum and deoxypyridinoline and N-telopeptide in urine depending on androgen deprivation and bone mineral density; finally to determine the effectiveness of these markers for diagnosis of osteoporosis and assess whether any of them can replace bone densitometry. Material and methods: this is a cross-sectional study in 548 patients with prostate cancer, controlled in the urology department at Hospital Vall d´Hebron. We measured bone mineral density by dual X-ray absortiometry using a densitometer Lunar DXP IQ-4977. For statistical analysis we used the U Mann-Whitney test, analysis of variance, binary logistic regression and ROC curves. Results: The overall prevalence of osteoporosis was 38.9%, with increase in the prevalence of osteoporosis as they advanced with androgen deprivation reaching 86.7% at 10 years. Patients on androgen deprivation only show alterations in serum phosphorus (higher levels than untreated), and vitamin D and PTH (lower levels than untreated). Phosphocalcic metabolism remains stable regardless of the densitometric diagnosis. Bone turnover markers, except total alkaline phosphatase, had higher levels in the androgen suppression group. Also markers tend to rise in proportion to the loss of bone mass. Bone alkaline phosphatase showed the highest area under the curve, however was not useful for diagnosis of osteoporosis. Conclusion: None of the analyzed bone turnover markers has been proven effective enough in the diagnosis of bone loss to be able to replace bone densitometry. Advisors/Committee Members: [email protected] (authoremail), true (authoremailshow), Morote Robles, Juan (director), Armengol Carrasco, Manuel (director), true (authorsendemail).

Subjects/Keywords: Cáncer de próstata; Supresión androgénica; Osteoporosis; Ciències de la Salut; 616.6

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Martínez Cuenca, E. (2012). Alteraciones del metabolismo fosfocálcico y óseo en cáncer de próstata bajo supresión androgénica: Utilidad de los marcadores de recambio óseo para diagnóstico de osteoporosis. (Thesis). Universitat Autònoma de Barcelona. Retrieved from http://hdl.handle.net/10803/363922

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Martínez Cuenca, Esther. “Alteraciones del metabolismo fosfocálcico y óseo en cáncer de próstata bajo supresión androgénica: Utilidad de los marcadores de recambio óseo para diagnóstico de osteoporosis.” 2012. Thesis, Universitat Autònoma de Barcelona. Accessed December 08, 2019. http://hdl.handle.net/10803/363922.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Martínez Cuenca, Esther. “Alteraciones del metabolismo fosfocálcico y óseo en cáncer de próstata bajo supresión androgénica: Utilidad de los marcadores de recambio óseo para diagnóstico de osteoporosis.” 2012. Web. 08 Dec 2019.

Vancouver:

Martínez Cuenca E. Alteraciones del metabolismo fosfocálcico y óseo en cáncer de próstata bajo supresión androgénica: Utilidad de los marcadores de recambio óseo para diagnóstico de osteoporosis. [Internet] [Thesis]. Universitat Autònoma de Barcelona; 2012. [cited 2019 Dec 08]. Available from: http://hdl.handle.net/10803/363922.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Martínez Cuenca E. Alteraciones del metabolismo fosfocálcico y óseo en cáncer de próstata bajo supresión androgénica: Utilidad de los marcadores de recambio óseo para diagnóstico de osteoporosis. [Thesis]. Universitat Autònoma de Barcelona; 2012. Available from: http://hdl.handle.net/10803/363922

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universitat Autònoma de Barcelona

11. Carrasco López, Cristian. Estudio anatómico, radiológico y clínico del colgajo de arteria intercostal anterior en el tratamiento de cáncer de mama.

Degree: Departament de Cirurgia, 2018, Universitat Autònoma de Barcelona

URL: http://hdl.handle.net/10803/572063

► Background: reconstruction of the anterior thorax is complex because of the presence of aesthetically important areas such as the breast, sternum, and upper abdomen. For… (more)

▼ Background: reconstruction of the anterior thorax is complex because of the presence of aesthetically important areas such as the breast, sternum, and upper abdomen. For this reason, a wide variety of pedicled perforator flaps have been described. The intercostal perforator flaps (ICAP) are one of these perforators flaps and are valuable for use in breast reconstruction surgery. Although the use of lateral intercostal artery perforator flaps for immediate breast reconstruction has been widely described, data on the use of the anterior ICAP (AICAP) flaps for this indication are limited. In this context, we describe the results of anatomical and radiological study and our clinical experience with AICAP flaps for breast reconstruction. Methods: in the first article, the location and characteristics of the anterior intercostal perforators were evaluated both anatomically and radiologically. The anatomical study was conducted in a set of 14 hemitrunk cadavers, and the radiologic study was performed retrospectively from a randomly selected set of images obtained from 30 female patients who underwent thoracic computed tomographic angiography for other health problems at the authors’ institution during the year 2015. The findings were then compared. In the second article, the anatomical findings were described under clinical point of view. Furthermore, we analyzed fourteen patients (mean BMI 23) who underwent partial breast resection for a quadrant breast cancer followed by breast reconstruction with an intercostal perforator flap. The mean resection size was 6 × 5 × 5.5 cm (range 3-8 × 3.5-7 × 4-8 cm). The main outcome measures were pre-operative and postradiotherapy health-related quality of life assessed with the BREAST-Q reconstruction survey. Results: in the first article, a total of 60 perforators in 14 hemitrunks were identified and mapped. Perforators were found in all hemithoraces. Hemitrunk was divided in thirds. The lateral third donor location was the most reliable zone, containing larger and more numerous perforators compared with the other donor regions. According to the radiologic study, a total of 164 perforators in 30 computed tomographic angiographs were identified and mapped. Perforators were found in all thoraxes. In the second article and according to anatomical study, at least one perforator was found in each third of hemitrunks dissected. The mean of perforator size was in diameter 0.42 ± 0.05 mm and in length 3.1 ± 0.36 cm. In clinical outcomes, the mean of flap size was 16 × 5 × 3 cm (range 14-19 × 3-8 × 2-5 cm). The mean surgical time was 120 min (range 109-125 min). Only one partial flap failure was detected. No postoperative changes in breast size were observed, although soft tissue changes were observed in four patients after radiotherapy. The mean BREAST-Q scores changes were 0 in satisfaction with the breast, 5 in satisfaction with outcome, 0 in psychosocial well-being, 6.15 in sexual well being, and 34.69 in physical well-being. Conclusions: the authors found that the intercostal perforator… Advisors/Committee Members: [email protected] (authoremail), true (authoremailshow), Julián Ibáñez, Juan Francisco (director), Higueras Suñe, Ma Carmen (director), Fernández-Llamazares Rodríguez, Jaume (tutor), true (authorsendemail).

Subjects/Keywords: Cirugia conservadora de mama; Cirurgía consevadora de mama; Forest conserv insurgery; Penjoll; Colgajo; Flap; Càncer de mama; Cáncer de mama; Brecost cancer; Ciències de la Salut; 617

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APA (6^th Edition):

Carrasco López, C. (2018). Estudio anatómico, radiológico y clínico del colgajo de arteria intercostal anterior en el tratamiento de cáncer de mama. (Thesis). Universitat Autònoma de Barcelona. Retrieved from http://hdl.handle.net/10803/572063

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Carrasco López, Cristian. “Estudio anatómico, radiológico y clínico del colgajo de arteria intercostal anterior en el tratamiento de cáncer de mama.” 2018. Thesis, Universitat Autònoma de Barcelona. Accessed December 08, 2019. http://hdl.handle.net/10803/572063.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Carrasco López, Cristian. “Estudio anatómico, radiológico y clínico del colgajo de arteria intercostal anterior en el tratamiento de cáncer de mama.” 2018. Web. 08 Dec 2019.

Vancouver:

Carrasco López C. Estudio anatómico, radiológico y clínico del colgajo de arteria intercostal anterior en el tratamiento de cáncer de mama. [Internet] [Thesis]. Universitat Autònoma de Barcelona; 2018. [cited 2019 Dec 08]. Available from: http://hdl.handle.net/10803/572063.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Carrasco López C. Estudio anatómico, radiológico y clínico del colgajo de arteria intercostal anterior en el tratamiento de cáncer de mama. [Thesis]. Universitat Autònoma de Barcelona; 2018. Available from: http://hdl.handle.net/10803/572063

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universitat Autònoma de Barcelona

12. Silva Vergara, Claudio Andrés. Seguridad oncológica de los injertos de tejido adiposo en procedimientos de reconstrucción mamaria oncológica.

Degree: Departament de Cirurgia, 2017, Universitat Autònoma de Barcelona

URL: http://hdl.handle.net/10803/457853

► The autologous fat graft or lipofilling technique revolutionized the management of tissue losses and now is widely used in plastic surgery for breast reconstruction. However,… (more)

▼ The autologous fat graft or lipofilling technique revolutionized the management of tissue losses and now is widely used in plastic surgery for breast reconstruction. However, concerns have been raised regarding the potential oncologic risks of these procedures. Cells could express protumorigenic factors; stem cells transform within the graft or even this new tissue could compromise our ability to detect breast disease. A number of new techniques of fat preparation have been described with the ultimate goal of improving adipocyte purification and stem cell selection. Inevitably, the intentional placement of regenerating tissue at the site of a previous tumor bed raises questions regarding the possibility of promoting a cancer recurrence. In experimental studies, adipocytes and white adipose tissue progenitors are able to produce different growth factors involved in tumorigenesis. They could act on cancer cell cycle through autocrine, paracrine, and endocrine secretions promoting tumor progression. In this current dilemma between improving patients' quality of life and the arising evidence that fat graft might have cooperative roles in breast cancer progression, we designed a clinical study to analyze the oncologic outcome of lipofilling procedures in breast cancer patients. In the first paper of this thesis, an exhaustive review of all patients who underwent lipofilling technique for breast reconstruction at Hospital Clinic of Barcelona since January 2007 to December 2014, were analyzed for oncological findings, lipofilling technique issues and its complications. We reviewed 319 lipofilling procedures from 195 patients. They underwent a mean of 1.6 lipofilling sessions (range, 1-6). Lipofilling was performed under outpatient surgery in majority of the cases, otherwise, inpatients surgery were usually associated with other procedures. We observed 26 complications from 319 procedures (8.2%). The most common complication was liponecrosis and oil cyst. Regarding oncological results; 4 local, 2 regional and 4 metastases were observed as first oncological event of relapse during a mean follow-up from oncologic surgery of 74 months, and the locoregional recurrence rate was 1.08% per year. On the second paper, we use a matched control group to analyze whether lipofilling procedures have any influence over recurrence in patients who underwent breast cancer surgery. Between January of 2007 and December of 2015, 315 breast lipofilling procedures from 205 breast cancer patients treated with fat grafting for breast cancer reconstructions were included. They were matched with 2 randomly selected patients with breast cancer who underwent surgery treatment but did not undergo any lipofilling procedures for 6 variables: date of primary cancer operation (within 3 years), age (within 5 years), type of cancer surgery, histopathology, lymphatic involvement, and estrogen receptor status. In a follow-up of 88.7 months, no relapse or mortality differences were found between the lipofilling and control groups. Moreover, no differences… Advisors/Committee Members: [email protected] (authoremail), true (authoremailshow), Grande Posa, Luis (director), Fontdevila Font, Joan (director), true (authorsendemail).

Subjects/Keywords: Emplet de greix; Injertos de tejido graso; Lipofilling; Reconstrucció de mama; Reconstruccón de mama; Breast reconstruction; Risc oncològic; Riesgo oncológico; Oncological risk; Ciències de la Salut; 617

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APA (6^th Edition):

Silva Vergara, C. A. (2017). Seguridad oncológica de los injertos de tejido adiposo en procedimientos de reconstrucción mamaria oncológica. (Thesis). Universitat Autònoma de Barcelona. Retrieved from http://hdl.handle.net/10803/457853

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Silva Vergara, Claudio Andrés. “Seguridad oncológica de los injertos de tejido adiposo en procedimientos de reconstrucción mamaria oncológica.” 2017. Thesis, Universitat Autònoma de Barcelona. Accessed December 08, 2019. http://hdl.handle.net/10803/457853.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Silva Vergara, Claudio Andrés. “Seguridad oncológica de los injertos de tejido adiposo en procedimientos de reconstrucción mamaria oncológica.” 2017. Web. 08 Dec 2019.

Vancouver:

Silva Vergara CA. Seguridad oncológica de los injertos de tejido adiposo en procedimientos de reconstrucción mamaria oncológica. [Internet] [Thesis]. Universitat Autònoma de Barcelona; 2017. [cited 2019 Dec 08]. Available from: http://hdl.handle.net/10803/457853.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Silva Vergara CA. Seguridad oncológica de los injertos de tejido adiposo en procedimientos de reconstrucción mamaria oncológica. [Thesis]. Universitat Autònoma de Barcelona; 2017. Available from: http://hdl.handle.net/10803/457853

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universitat Autònoma de Barcelona

13. Villalba i Modol, Jordi. Com afecta el disseny d’una pròtesi en la millora de la qualitat de vida.

Degree: Departament de Cirurgia, 2015, Universitat Autònoma de Barcelona

URL: http://hdl.handle.net/10803/322803

► Knee replacement has been proved effective for the treatment of advanced Knee osteoarthritis regarding function recovery and improvement of life quality in patients who undergo… (more)

▼ Knee replacement has been proved effective for the treatment of advanced Knee osteoarthritis regarding function recovery and improvement of life quality in patients who undergo surgery. Increased life expectancy of the population on one side, and the willingness of society to have better quality of life and health, has also increased the number of knee replacements implanted, almost exponentially, causing an important economical social impact. The main hypothesis of this study is to demonstrate that the outcomes obtained from three different prosthesis type designs, show no differences when it comes to life-quality improvement perceived by patients, as reflected by the WOMAC and SF-36 scales. We studied 133 patients undergoing knee replacement with one of the following: A posteroestabilizated model (PS), a cruciate retained model (CR) or a mobile bearing model (M). We carried out a population-based, observational, prospective and unicentric study to evaluate clinical practice at our hospital. We concluded that there are no differences between the three types of models of arthroplasties when it comes to life quality improvement. Preoperative baseline variables (age, gender, leg dominance, BMI, comorbidities and ASA) showed no influence over life-quality values previously obtained and therefore no influence on the WOMAC and SF -36 scales. The preoperative WOMAC score has been seen to predispose a different evolution in postoperative WOMAC. Patients with a low preoperative WOMAC score achieved a greater improvement in the postoperative WOMAC. The preoperative SF 36, however, did not influence postoperative values. Assessing whether the final function studied with KSS was related to an improvement in the quality of life we obtained the following. Good final function is related to good results in the WOMAC and SF-36 scales, although the latter is not significant. A good final function is associated with a high degree of patient satisfaction. A rise in quality of life was linked to a high degree of patient satisfaction. We did not observe differences depending on the type of prosthesis model used. Advisors/Committee Members: [email protected] (authoremail), true (authoremailshow), Cáceres i Palou, Enric (director), Torner Pifarré, Pere (director), true (authorsendemail).

Subjects/Keywords: Disseny; Diseño; Dessing; Pròtesi de genoll; Prótesis de rodilla; Knee arthroplasty; Qualitat de vida; Calidad de vida; Quality of life; Ciències de la Salut; 617

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APA (6^th Edition):

Villalba i Modol, J. (2015). Com afecta el disseny d’una pròtesi en la millora de la qualitat de vida. (Thesis). Universitat Autònoma de Barcelona. Retrieved from http://hdl.handle.net/10803/322803

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Villalba i Modol, Jordi. “Com afecta el disseny d’una pròtesi en la millora de la qualitat de vida.” 2015. Thesis, Universitat Autònoma de Barcelona. Accessed December 08, 2019. http://hdl.handle.net/10803/322803.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Villalba i Modol, Jordi. “Com afecta el disseny d’una pròtesi en la millora de la qualitat de vida.” 2015. Web. 08 Dec 2019.

Vancouver:

Villalba i Modol J. Com afecta el disseny d’una pròtesi en la millora de la qualitat de vida. [Internet] [Thesis]. Universitat Autònoma de Barcelona; 2015. [cited 2019 Dec 08]. Available from: http://hdl.handle.net/10803/322803.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Villalba i Modol J. Com afecta el disseny d’una pròtesi en la millora de la qualitat de vida. [Thesis]. Universitat Autònoma de Barcelona; 2015. Available from: http://hdl.handle.net/10803/322803

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universitat Autònoma de Barcelona

14. Sheriff, Hemin Oathman. Supraclavicular artery perforator flap anatomical study, imaging findings, and clinical applications.

Degree: Departament de Cirurgia, 2018, Universitat Autònoma de Barcelona

URL: http://hdl.handle.net/10803/462763

► Background: Supraclavicular artery flap is an excellent pedicled fasciocutaneous flap taken from skin of the shoulder and supraclavicular area for head and neck reconstruction. The… (more)

▼ Background: Supraclavicular artery flap is an excellent pedicled fasciocutaneous flap taken from skin of the shoulder and supraclavicular area for head and neck reconstruction. The color match, thinness, pliability, and hair free skin of supraclavicular artery flap parallels that of the head and neck region, and provides a superior cosmetic outcome when compared to free tissue transfer flaps from such as the forearm, abdomen, or thigh. The purpose of this study is to find the ideal technique for the preoperative mapping of the supraclavicular artery perforator flap, and also to determine the safe survival length of the flap. Methods: Between July 2013 and February 2017, A total of 74 cases were studied, they were aged between 19 and 85 years (mean age of 49.26 years), 32 males and 42 females, In this study, the following six imaging modalities were used for supraclavicular vascular tree visualization: 1) Handheld Doppler (HHD) 2) Triplex ultrasound (TU) 3) Computed Tomography Angiogram (CTA) 4) Magnetic Resonance Angiography' (MRA) 5) Digital Subtraction Angiography (DSA) 6) Indocyanine Green Fluorescent Angiograms (ICGA). Also 21 patients from the total of 74 cases, underwent head and neck reconstruction surgery, in which 25 supraclavicular flaps were used. Twelve of these cases had flaps following release and excision of burn contractures whereas the remaining 9 patients had flaps following wide excision of tumors. Results: Handheld Doppler identified perforators’ sites in 80% of the cases but showed no results for the course of the vessel. Triplex ultrasound identified the site of *perforators in 52.9% and partial mapping of the course of a supraclavicular artery in 64.7% of the cases. Computerized tomography angiogram showed the site of *perforators in 60%, and the course of supraclavicular artery completely in 45%, and partially in an additional 30%of the cases examined. Magnetic resonance angiography showed negative results for all parameters. Digital subtraction angiography showed the partial course of a supraclavicular artery in 62.5%, but showed no perforators. Indocyanine green angiogram showed the site of perforators in 60% and a partial course of supraclavicular artery distal to perforators in 60%. The length of the 25 flaps used varied according to the patient’s need. On average the length ranged from 12- 35 cm with a mean length of 20.76 cm. There was no total flap loss, however 3 of the flaps (12%) resulted in distal end necrosis. The results showed that all the flaps with distal necrosis had a length 23cm or longer. Furthermore, the flaps that had length below 23 cm had no necrosis, which consists of 14 flaps, (56%). Conclusions: ICG angiogram precisely shows the site of the perforators and superficial course of the artery in the real time of the test. Although CTA performed better in the mapping of the supraclavicular artery, but it has irradiation and the risk of contrast problems. The distal survival of the supraclavicular artery perforator flap is reliable below 22 cm, but the… Advisors/Committee Members: [email protected] (authoremail), true (authoremailshow), Masià, Jaume (director), Rius Cornadó, X. (Xavier) (tutor), true (authorsendemail).

Subjects/Keywords: Penjoll de perforant de l'artèria supraclavicular; Colgajo de perforante de la arteria supraclavicular; Supraclavicular artery perforator flap; Reconstrucció de cap i recollida; Reconstrucción de cabeza y cuello; Head and neck reconstruction; Ciències de la Salut; 617

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APA (6^th Edition):

Sheriff, H. O. (2018). Supraclavicular artery perforator flap anatomical study, imaging findings, and clinical applications. (Thesis). Universitat Autònoma de Barcelona. Retrieved from http://hdl.handle.net/10803/462763

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Sheriff, Hemin Oathman. “Supraclavicular artery perforator flap anatomical study, imaging findings, and clinical applications.” 2018. Thesis, Universitat Autònoma de Barcelona. Accessed December 08, 2019. http://hdl.handle.net/10803/462763.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Sheriff, Hemin Oathman. “Supraclavicular artery perforator flap anatomical study, imaging findings, and clinical applications.” 2018. Web. 08 Dec 2019.

Vancouver:

Sheriff HO. Supraclavicular artery perforator flap anatomical study, imaging findings, and clinical applications. [Internet] [Thesis]. Universitat Autònoma de Barcelona; 2018. [cited 2019 Dec 08]. Available from: http://hdl.handle.net/10803/462763.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Sheriff HO. Supraclavicular artery perforator flap anatomical study, imaging findings, and clinical applications. [Thesis]. Universitat Autònoma de Barcelona; 2018. Available from: http://hdl.handle.net/10803/462763

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universitat Autònoma de Barcelona

15. Jiménez Gómez, Luis Miguel. Síndrome de resección anterior de recto. Análisis de los factores asociados y su conocimiento entre la comunidad quirúrgica.

Degree: Departament de Cirurgia, 2019, Universitat Autònoma de Barcelona

URL: http://hdl.handle.net/10803/666757

► Introduction The advance in diagnosis and treatment of rectal cancer has allowed an improvement in prognosis. The technological development and the progression in the training… (more)

▼ Introduction The advance in diagnosis and treatment of rectal cancer has allowed an improvement in prognosis. The technological development and the progression in the training of specialized surgeons has resulted in an increase in the rate of sphincter-sparing surgery, and therefore in an increase in patients suffering from functional defecatory disorders after rectal cancer surgery. Aim and thesis Firstly, to assess the experience and perception of surgeons dedicated to the treatment of rectal cancer about their technical preferences as well as their etiopathogenic considerations in low anterior resection syndrome. Secondly, to analyze different factors potentially associated with development of low anterior resection syndrome. Mehod A survey was designed that covers several areas: the scope and experience of the surgeon, the technical preferences and aspects related to the low anterior resection syndrome. The results are described as descriptive statistics. On the other hand, a cross-sectional study was carried out in two third-level hospitals, in which patients who underwent rectal cancer with sphincter preservation between January 2001 and December 2009 were invited to fill in a validated defecatory function questionnaire ( "LARS score"). The variables under study were assessed by univariate and multivariate analyses. Results Sphincter preservation rate that surgeons estimate according to the survey is between 71 and 90%. The technique of choice is end-to-end anastomosis. Although there is awareness about low anterior resection syndrome, its severity is usually measured by clinical criteria without questionnaires. Almost 75% of surgeons interviewed believe that major low anterior resection syndrome does not affect more than 40% of patients. Likewise, they report that distance from anastomosis to anal margin is the most important risk factor. On the other hand, 56.2% of patients with low anterior resection suffer from "major" syndrome, 19.6% "minor" and 23.9% do not present the syndrome. In the multivariate analysis, total mesorectum excision and radiotherapy were independent risk factors for major low anterior resection syndrome. Conclusions Although there is awareness of low anterior resection syndrome, probability of suffering it and its severity is underestimated. The variable that shows the greatest strength of association with the severity of the anterior resection syndrome is radiotherapy, both preoperatively and postoperatively. Advisors/Committee Members: [email protected] (authoremail), true (authoremailshow), Espín Basany, Eloi (director), Sánchez García, José Luis (director), Armengol Carrasco, Manuel (director).

Subjects/Keywords: Cancer de recte; Cáncer de recto; Rectal cancer; Síndrome de resecció anterior baixa; Sindrome de resección anterior baja; Low anterior resection syndrome; Factors de risc/factores de riesgo; Risk factors; Ciències de la Salut; 617

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APA (6^th Edition):

Jiménez Gómez, L. M. (2019). Síndrome de resección anterior de recto. Análisis de los factores asociados y su conocimiento entre la comunidad quirúrgica. (Thesis). Universitat Autònoma de Barcelona. Retrieved from http://hdl.handle.net/10803/666757

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Jiménez Gómez, Luis Miguel. “Síndrome de resección anterior de recto. Análisis de los factores asociados y su conocimiento entre la comunidad quirúrgica.” 2019. Thesis, Universitat Autònoma de Barcelona. Accessed December 08, 2019. http://hdl.handle.net/10803/666757.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Jiménez Gómez, Luis Miguel. “Síndrome de resección anterior de recto. Análisis de los factores asociados y su conocimiento entre la comunidad quirúrgica.” 2019. Web. 08 Dec 2019.

Vancouver:

Jiménez Gómez LM. Síndrome de resección anterior de recto. Análisis de los factores asociados y su conocimiento entre la comunidad quirúrgica. [Internet] [Thesis]. Universitat Autònoma de Barcelona; 2019. [cited 2019 Dec 08]. Available from: http://hdl.handle.net/10803/666757.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Jiménez Gómez LM. Síndrome de resección anterior de recto. Análisis de los factores asociados y su conocimiento entre la comunidad quirúrgica. [Thesis]. Universitat Autònoma de Barcelona; 2019. Available from: http://hdl.handle.net/10803/666757

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universitat Autònoma de Barcelona

16. Amilibia Cabeza, Emilio. Caracterización de la hipoacusia en la enfermedad de Paget.

Degree: Departament de Cirurgia, 2018, Universitat Autònoma de Barcelona

URL: http://hdl.handle.net/10803/664352

► Introduction and objectives: Paget’s disease of bone (PDB) may lead to hearing loss. The present study is conducted with the aim of measuring, characterizing, determining… (more)

▼ Introduction and objectives: Paget’s disease of bone (PDB) may lead to hearing loss. The present study is conducted with the aim of measuring, characterizing, determining the risk factors for hearing loss and analyse the possible relation of hearing loss with tomography findings in a group of subjects with PDB. Methods: An observational, transversal, case-control study was conducted, a cohort of 76 subjects diagnosed of Paget’s disease of bone (PDB) in the case group and a control group of 134 subjects were included. Clinical, demographic, audiometric and tomographic data (by means of a CT scan study) were analysed. Results: The comparative analysis between the subjects in the PDB group and the control group found that the case group showed higher hearing thresholds (39,51dB) comparing with the control group (37,28 dB) (p=0,069) and presented a greater rate of conductive hearing loss (22,76%) than the control group (12,05%) (p=0,0062). The study of risk factors for hearing loss found that skull involvement in bone scintigraphy, age and high blood pressure were risk factors for higher hearing impairment in PDB. The CT scan data showed that subjects in the PDB group had lower temporal bone density (Hounsfield Units, HU) comparing with the control group. It was also found that the otic capsule bone density in the PDB group correlated with both the air and bone conduction hearing thresholds (p<0,05) and that the finding of an air-bone gap in the audiogram correlated with Paget’s disease temporal bone involvement. Conclusions: − The 63,45% of subjects with Paget’s disease of bone (PDB) suffer hearing loss with a hearing threshold of 39,51dB on average. − The subjects with PDB showed a deeper hearing loss and a higher proportion of conductive type than the control group. − The patients with PDB and skull involvement presented a more severe hearing loss compared with the subjects without skull involvement. Skull involvement and age were found to be risk factors for hearing loss. − In the PDB group both the air and bone conduction hearing thresholds correlated with the otic capsule bone density. Advisors/Committee Members: [email protected] (authoremail), true (authoremailshow), Quer, Miquel (director), Roca-Ribas Serdà, Francisco (director).

Subjects/Keywords: Hipoacúsia; Hipoacusia; Hearing loss; Malatia de Paget; Enfermedad de Paget; Paget's disease; Ciències de la Salut; 617

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APA (6^th Edition):

Amilibia Cabeza, E. (2018). Caracterización de la hipoacusia en la enfermedad de Paget. (Thesis). Universitat Autònoma de Barcelona. Retrieved from http://hdl.handle.net/10803/664352

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Amilibia Cabeza, Emilio. “Caracterización de la hipoacusia en la enfermedad de Paget.” 2018. Thesis, Universitat Autònoma de Barcelona. Accessed December 08, 2019. http://hdl.handle.net/10803/664352.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Amilibia Cabeza, Emilio. “Caracterización de la hipoacusia en la enfermedad de Paget.” 2018. Web. 08 Dec 2019.

Vancouver:

Amilibia Cabeza E. Caracterización de la hipoacusia en la enfermedad de Paget. [Internet] [Thesis]. Universitat Autònoma de Barcelona; 2018. [cited 2019 Dec 08]. Available from: http://hdl.handle.net/10803/664352.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Amilibia Cabeza E. Caracterización de la hipoacusia en la enfermedad de Paget. [Thesis]. Universitat Autònoma de Barcelona; 2018. Available from: http://hdl.handle.net/10803/664352

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universitat Autònoma de Barcelona

17. Esquivel Miranda, Miguel Ángel. Impacto del grado de resección quirúrgica en la calidad de vida y la supervivencia en pacientes con gliomas. Resultados de un estudio prospectivo.

Degree: Departament de Cirurgia, 2017, Universitat Autònoma de Barcelona

URL: http://hdl.handle.net/10803/459082

► Diffuse gliomas represent the most common primary malignant tumors of the Central Nervous System. Traditionally grade III and IV gliomas or glioblastoma (GBM) are referred… (more)

▼ Diffuse gliomas represent the most common primary malignant tumors of the Central Nervous System. Traditionally grade III and IV gliomas or glioblastoma (GBM) are referred to high grade (HGG) and grade I and II low grade (LGG). The impact of the degree of surgical resection on Quality of Life (QoL) and survival in patients with gliomas at Hospital México, Costa Rica, from September 2009 to April 2015, was analyzed. The degree of resection was evaluated in digital studies of nuclear magnetic resonance and computed tomography through digital volumetric measurement, before and after surgery. The baseline QoL test was evaluated in 187 patients, The European Organization for Research and Treatment of Cancer Core QOL Questionnaire (EORTC QLQ-C30) and the Sickness Impact Profile (SIP), also the Mini Mental Status Test Examination and the Karnofsky Scale (KPS). Of the 187 patients who performed the baseline test, 117 (62.6%) performed the EORTC QLQ-C30 and SIP postoperative questionnaires at 8 weeks. Survival was correlated according to the percentage of resection: 1-biopsy (< 10% of the lesion); 2-partial (10 to < 90%) and 3-subtotal/complete (> 90 to 100%) and residual tumor volume. The 58.8% of the patients were men, mean age was 49.4 ± 15.1 years. Patients with grade IV tumors were the majority (65.3%), followed by patients with grade II gliomas (20.1%); the HGG accounted for 77.2%. The KPS was identified as the predictor variable best related to baseline QoL variables and a low KPS at the time of diagnosis was associated, for the whole series, with a greater risk of deterioration in postoperative tests in intellectual / emotive aspects (Intellectual Activity of SIP OR: 1.05; CI 95%: 1.02-1.08; p = 0.007; Emotional Function EORTC QLQ-C30 OR: 1.05; CI 95%: 1.01-1.09; p = 0.038) and Fatigue EORTC QLQ C-30 OR: 1.25; CI 95%: 1.04- 1.49; p = 0.016). The impact on baseline QoL of SIP and EORTC QLQ-C30 in LGG and HGG was very similar. The affectation of the cognitive functions in the basal QoL tests was relevant. The most committed category of the SIP was the Intellectual Activity of the Psychosocial Dimension, (44.8 points, min: 0.0, max 100) for the whole series. The Physical categories were the least compromised, the Physical Dimension of the SIP presented median 23.1 points (min: 0.0; max: 87.8) for the whole series and the physical function of EORTC QLQ-C30 was the least compromised in patients with LGG (median 93.2 points, min: 0.0, max: 100) and the second in HGG (median 73.3 points min: 0.0; max: 100). Patients with tumors in the dominant hemisphere had greater cognitive impairment and lesions in the centromedial region of the cerebral hemispheres were significantly affected in most SIP and EORTC QLQ-C30 categories. The QoL scores improved after surgery in all of the SIP and EORTC QLQ-C30 evaluated variables when the tumor resection percentage was subtotal/complete and worsened when a biopsy was performed les in all dimensions, especially in the physical categories. Survival for the… Advisors/Committee Members: [email protected] (authoremail), true (authoremailshow), Sahuquillo Barris, Juan (director), true (authorsendemail).

Subjects/Keywords: Gliomas; Qualitat de vida; Calidad de vida; Quality of life; Supervivència; Supervivencia; Survival; Ciències de la Salut; 616.8

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APA (6^th Edition):

Esquivel Miranda, M. �. (2017). Impacto del grado de resección quirúrgica en la calidad de vida y la supervivencia en pacientes con gliomas. Resultados de un estudio prospectivo. (Thesis). Universitat Autònoma de Barcelona. Retrieved from http://hdl.handle.net/10803/459082

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Esquivel Miranda, Miguel Ángel. “Impacto del grado de resección quirúrgica en la calidad de vida y la supervivencia en pacientes con gliomas. Resultados de un estudio prospectivo.” 2017. Thesis, Universitat Autònoma de Barcelona. Accessed December 08, 2019. http://hdl.handle.net/10803/459082.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Esquivel Miranda, Miguel Ángel. “Impacto del grado de resección quirúrgica en la calidad de vida y la supervivencia en pacientes con gliomas. Resultados de un estudio prospectivo.” 2017. Web. 08 Dec 2019.

Vancouver:

Esquivel Miranda M�. Impacto del grado de resección quirúrgica en la calidad de vida y la supervivencia en pacientes con gliomas. Resultados de un estudio prospectivo. [Internet] [Thesis]. Universitat Autònoma de Barcelona; 2017. [cited 2019 Dec 08]. Available from: http://hdl.handle.net/10803/459082.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Esquivel Miranda M�. Impacto del grado de resección quirúrgica en la calidad de vida y la supervivencia en pacientes con gliomas. Resultados de un estudio prospectivo. [Thesis]. Universitat Autònoma de Barcelona; 2017. Available from: http://hdl.handle.net/10803/459082

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universitat Autònoma de Barcelona

18. Sanz Moreno, Silvia. Eficacia y factores pronósticos de la ciclofotocoagulación con láser diodo transescleral en los pacientes con glaucoma por silicona intraocular.

Degree: Departament de Cirurgia, 2017, Universitat Autònoma de Barcelona

URL: http://hdl.handle.net/10803/456690

► Aims: The main purpose of this doctoral thesis is to assess the efficacy of transcleral cyclodiode (TCD) in terms of reduction of intraocular pressure (IOP)… (more)

▼ Aims: The main purpose of this doctoral thesis is to assess the efficacy of transcleral cyclodiode (TCD) in terms of reduction of intraocular pressure (IOP) and the evolution of clinical signs and symptoms in patients with previous retinal detachment and secondary silicone oil glaucoma (SOG). Other aspects evaluated are the efficacy of retreatment after failure of previous TCD surgery, complications of the surgical technique, prognostic factors associated with success and long-term survival of the procedure. Methods: This is an interventional retrospective non-comparative study. The sample size is 55 eyes from 55 patients with the diagnosis of SOG. The main variable of the study is the value of intraocular pressure in terms of success or failure. The measurements have been performed before and at 1,3,6, 12 and 24 months after the surgical procedure. The secondary variables evaluated are visual acuity, presence of ocular pain and corneal edema, number of medications and laser power. The data are summarised in terms of mean, median, standard deviation, first and third quartil and range for quantitative variables and bar charts for qualitative variables. The data were analyzed using the Friedman test, Chi square test, Fischer test, Wilcoxon test, logistic regression in terms of odds ratio and Kaplan Meier for survival analysis. Results: An IOP decrease after surgery has been observed along the entire follow up for the first, second and third procedures (Friedman test p= 0,0030, p < 0,0001 and p =0,0022, respectively). The IOP values have shown significant differences with silicone oil type –mainly 1000cs- (Fisher test p=0,0024) and previous silicone oil removal (Fisher test p=0,0047); in both cases a failure of the technique has been observed in most patients. The average of retreatment is 1,67. A complete and stable improvement of the ocular pain (Fisher test p < 0,0009) and corneal edema (Fisher test p <0,0001) has been achieved. There´s a significant reduction in the number of medications following the first surgical procedure with an average of 1,2 (Friedman test p= 0,0307). After the first TCD procedure, no significant decrease in visual acuity has been observed at the end of the 24 months follow up (Tau b_Kendall p =0,9231). However, chronic hypotony increases after 12 month after the first surgery (LR.Chi Square p=0,0020). Among the preoperative variables evaluated for prognostic factors, the use of 5000 cts silicone oil, the presence of vitreoretinal proliferation (VRP) and non-surgical removal of silicone oil have been associated with a significant success of the CT technique in the logistic regression analysis (OR = 18,20, OR = 4 and OR 8,26 respectively). The value of IOP at three months after TC surgery has been found as a predictive value of success at the 12 months period in the 69,2% of patients. The Kaplan Meier method has shown a survival of the technique after the first procedure of 0,6364 and 0,4545 at the 3 months and 24 months period. No significant differences in survival have… Advisors/Committee Members: [email protected] (authoremail), true (authoremailshow), García Arumí, José (director), true (authorsendemail).

Subjects/Keywords: Ciclofotocoagulació; Ciclofotocoagulación; Cyclophotocoagulation; Oli de silicona intraocular; Aceite de silicona intraocular; Intraocular silicone oil; Glaucoma; Ciències de la Salut; 61

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APA (6^th Edition):

Sanz Moreno, S. (2017). Eficacia y factores pronósticos de la ciclofotocoagulación con láser diodo transescleral en los pacientes con glaucoma por silicona intraocular. (Thesis). Universitat Autònoma de Barcelona. Retrieved from http://hdl.handle.net/10803/456690

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Sanz Moreno, Silvia. “Eficacia y factores pronósticos de la ciclofotocoagulación con láser diodo transescleral en los pacientes con glaucoma por silicona intraocular.” 2017. Thesis, Universitat Autònoma de Barcelona. Accessed December 08, 2019. http://hdl.handle.net/10803/456690.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Sanz Moreno, Silvia. “Eficacia y factores pronósticos de la ciclofotocoagulación con láser diodo transescleral en los pacientes con glaucoma por silicona intraocular.” 2017. Web. 08 Dec 2019.

Vancouver:

Sanz Moreno S. Eficacia y factores pronósticos de la ciclofotocoagulación con láser diodo transescleral en los pacientes con glaucoma por silicona intraocular. [Internet] [Thesis]. Universitat Autònoma de Barcelona; 2017. [cited 2019 Dec 08]. Available from: http://hdl.handle.net/10803/456690.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Sanz Moreno S. Eficacia y factores pronósticos de la ciclofotocoagulación con láser diodo transescleral en los pacientes con glaucoma por silicona intraocular. [Thesis]. Universitat Autònoma de Barcelona; 2017. Available from: http://hdl.handle.net/10803/456690

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universitat Autònoma de Barcelona

19. Graell Martín, Xavier. Estudio de la vía lagrimal después de cirugía de cataratas.

Degree: Departament de Cirurgia, 2015, Universitat Autònoma de Barcelona

URL: http://hdl.handle.net/10803/377469

► PURPOSE: To study the role of nasolacrimal drainage obstruction in patients with epiphora after cataract surgery. DESIGN: Prospective, observational and non comparative study METHODS: A… (more)

Subjects/Keywords: Epífora; Epiphora; Cirurgia de cataracta; Cirugía de catarata; Cataract surgery; Estenosi punt; Estenosis punto; Punctal stenosis; Ciències de la Salut; 617

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APA (6^th Edition):

Graell Martín, X. (2015). Estudio de la vía lagrimal después de cirugía de cataratas. (Thesis). Universitat Autònoma de Barcelona. Retrieved from http://hdl.handle.net/10803/377469

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Graell Martín, Xavier. “Estudio de la vía lagrimal después de cirugía de cataratas.” 2015. Thesis, Universitat Autònoma de Barcelona. Accessed December 08, 2019. http://hdl.handle.net/10803/377469.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Graell Martín, Xavier. “Estudio de la vía lagrimal después de cirugía de cataratas.” 2015. Web. 08 Dec 2019.

Vancouver:

Graell Martín X. Estudio de la vía lagrimal después de cirugía de cataratas. [Internet] [Thesis]. Universitat Autònoma de Barcelona; 2015. [cited 2019 Dec 08]. Available from: http://hdl.handle.net/10803/377469.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Graell Martín X. Estudio de la vía lagrimal después de cirugía de cataratas. [Thesis]. Universitat Autònoma de Barcelona; 2015. Available from: http://hdl.handle.net/10803/377469

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universitat Autònoma de Barcelona

20. Servián Vives, Pol. Clinical significance of prostatic proliferative inflammatory atrohpy.

Degree: Departament de Cirurgia, 2016, Universitat Autònoma de Barcelona

URL: http://hdl.handle.net/10803/386532

► Background: Proliferative inflammatory atrophy (PIA) has been involved in prostatic carcinogenesis. Proliferative epithelium in PIA may progress to high-grade prostatic intraepithelial neoplasia (HGPIN) or adenocarcinoma… (more)

▼ Background: Proliferative inflammatory atrophy (PIA) has been involved in prostatic carcinogenesis. Proliferative epithelium in PIA may progress to high-grade prostatic intraepithelial neoplasia (HGPIN) or adenocarcinoma or both. However, little is known about the clinical significance of a PIA finding in negative prostate biopsies (PBs). A preliminary review of the current literature has been done.(1st article) Objectives: 1)Determine the incidence of PIA in PBs with and without prostate cancer (PCa) and RPs, its association to HGPIN and tumor aggressiveness.(2nd article) 2)Determine the prognostic value of PIA finding in a negative PB regarding PCa risk and agressiveness.(3rd article) Methods: Retrospective and observational study of PIA lesion in 528 extended PBs and 200 RPs. Outcome measurements: PIA, HGPIN, PCa incidence, Gleason score, clinical and pathologic tumor stage and insignificant tumor rate.(2nd article) Retrospective and observational study of 474 men scheduled to repeated PBs. Assessment of PIA and its extension in the previous biopsy. PCa detection rate and tumor aggressiveness. Age, serum total PSA, free PSA, percent free PSA (%fPSA), digital rectal exam (DRE), prostate volume (PV), PSA density (PSAD), PSA kinetics (PSAV and PSADT) findings of PIA and HGPIN and number of affected cores in previous PBs were included in the univariate and multivariate analysis. Aggressive tumors were considered when any Gleason pattern 4 was found.(3rd article) Results: Overall incidence of PIA and HGPIN was 30.3% and 54% in extended PBs. In RPS, the incidence was 30.5% and 72%, respectively. No significant association was found between PIA and HGPIN. Overall PCa detection rate in PBs was 38.1%. PCa was found in 27.5% PBs with PIA and 42.7% of those without PIA, p<0.001. In contrast, PCa was detected in 50.9% of PBs with HGPIN and 23% of those without HGPIN, p=0.001. Multivariate analysis revealed that PIA decreased the risk of PCa, OR: 0.59 (95%CI:0.37–0.95), p=0.029, while HGPIN increased OR: 3.16 (95%CI:2.04–4.90), p=0.001. PIA was not related to Gleason grade and clinical stage, however it was associated to an insignificant tumors increase, OR:3.08 (95%CI:1.09–8.7), p=0.033. The information in RPs suggests that PIA is associated with less aggressive tumors and a higher probability of insignificant tumors.(2nd article) In the analysis of 474 men that underwent repeated PBs, PCa was detected in 133 men (28.1%). Age, serum total PSA, %fPSA, PV, PSAD, PSAV, PSADT and PIA finding were significantly associated to PCa detection. However, only age, OR:1.061 (95%CI:1.025-1.098), p=0.001; DRE, OR:1.755 (95%CI:1.054-2.923), p=0.031; %fPSA, OR:0.963 (95%CI: 0.933-0.996), p=0.028; PV, OR:0.983 (95%CI:0.972-0.994), p=0.002 and PIA finding, OR:0.491 (95%CI:0.291-0.828), p=0.008, were independent predictors of PCa detection. PCa was found in 18% of 159 men with previous PIA finding while in 33% of 315 men without previous PIA (p=0.001). None of the studied parameters including PIA in the previous biopsy were related with… Advisors/Committee Members: [email protected] (authoremail), true (authoremailshow), Morote Robles, Juan (director), true (authorsendemail).

Subjects/Keywords: Càncer de pròstata; Cáncer de próstata; Postate cancer; Testosterona; Testosterone; Deprivació androgènica; Deprivación androgénica; Androgen deprivation; Ciències de la Salut; 616.6

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APA (6^th Edition):

Servián Vives, P. (2016). Clinical significance of prostatic proliferative inflammatory atrohpy. (Thesis). Universitat Autònoma de Barcelona. Retrieved from http://hdl.handle.net/10803/386532

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Servián Vives, Pol. “Clinical significance of prostatic proliferative inflammatory atrohpy.” 2016. Thesis, Universitat Autònoma de Barcelona. Accessed December 08, 2019. http://hdl.handle.net/10803/386532.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Servián Vives, Pol. “Clinical significance of prostatic proliferative inflammatory atrohpy.” 2016. Web. 08 Dec 2019.

Vancouver:

Servián Vives P. Clinical significance of prostatic proliferative inflammatory atrohpy. [Internet] [Thesis]. Universitat Autònoma de Barcelona; 2016. [cited 2019 Dec 08]. Available from: http://hdl.handle.net/10803/386532.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Servián Vives P. Clinical significance of prostatic proliferative inflammatory atrohpy. [Thesis]. Universitat Autònoma de Barcelona; 2016. Available from: http://hdl.handle.net/10803/386532

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universitat Autònoma de Barcelona

21. Regis Plácido, Lucas. Valor de la testosterona libre en el diagnóstico y seguimiento del cáncer de próstata.

Degree: Departament de Cirurgia, 2016, Universitat Autònoma de Barcelona

URL: http://hdl.handle.net/10803/386533

► Since Huggins and Hodges published the prostate cancer hormone dependence theory in 1941, high levels of serum testosterone have been associated with the prostatic carcinogenesis.… (more)

▼ Since Huggins and Hodges published the prostate cancer hormone dependence theory in 1941, high levels of serum testosterone have been associated with the prostatic carcinogenesis. However, there is a lack of knowledge about the real role of testosterone in the prostatic neoplasm. Serum testosterone is mainly bounded with sex hormone binding globulin and albumin and only 1-2% is found as free testosterone, the biologically active hormone isoform. Advanced prostate cancer patients under androgen deprivation therapy have long overall survival and survival free of progression rates when testosterone is kept in low levels. Historically, castration has been defined as total testosterone lower than 50 ng/dL, although optimal degree of testosterone suppression following castration remains in question. Current guidelines recommend serum testosterone determinations to evaluate the androgen deprivation therapy efficacy and, furthermore, to diagnose castration resistance status. Because free testosterone is the active isoform of serum testosterone, we believe that it correlates better with intraprostatic environment than total testosterone. The main objective of our thesis project was to compare total and free testosterone in the I. prostate cancer diagnose; II. tumor aggressiveness prediction; and III. control of patients under androgen deprivation therapy as a survival free of castration resistance predictor. Our study was performed in two groups of patients that represent different moments of the natural history of the disease. 3364 men under prostate cancer suspicious due to rising PSA and/or abnormal digital rectal examination (DRE) integrated the prospective collected database 1. 126 patients under androgen deprivation therapy with LHRH agonist due to advanced prostate cancer histologically diagnosed integrated the retrospective collected database 2. Both databases included clinical-demographic data (age, BMI, total and free PSA, DRE, prostatic volume, biopsy result, Gleason score, pathologic stage [TNM 2002]) and hormone profile (total and free testosterone). The intervention performed was serum total testosterone measurement by competitive enzymatic chemiluministent assay with lower level of detection of 10.0 ng/dL (Immulite 2500 automated analyzer, DPC Inc., Los Angeles, CA, USA) and serum free testosterone measurement by radioinmunoanalysis assay with lower limit of detection of 0.05 pg/mL (DPC Inc., Los Angeles, CA, USA). Main endpoints were determine the relation between total and free testosterone and prostate cancer detection and its aggressiveness (database 1); and analyze total and free testosterone predictive values in survival free of castration resistance in order to establish the lower threshold with clinical impact in patients under androgen deprivation therapy (database 2). We conclude that I. low levels of total and free testosterone increment the risk of prostate cancer detection, II. no free or total testosterone levels showed any association with tumor… Advisors/Committee Members: [email protected] (authoremail), true (authoremailshow), Morote Robles, Juan (director), true (authorsendemail).

Subjects/Keywords: Càncer de pròstata; Cáncer de próstata; Postate cancer; Testosterona; Testosterone; Deprivació androgènica; Deprivación androgénica; Androgen deprivation; Ciències de la Salut; 616.6

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Regis Plácido, L. (2016). Valor de la testosterona libre en el diagnóstico y seguimiento del cáncer de próstata. (Thesis). Universitat Autònoma de Barcelona. Retrieved from http://hdl.handle.net/10803/386533

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Regis Plácido, Lucas. “Valor de la testosterona libre en el diagnóstico y seguimiento del cáncer de próstata.” 2016. Thesis, Universitat Autònoma de Barcelona. Accessed December 08, 2019. http://hdl.handle.net/10803/386533.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Regis Plácido, Lucas. “Valor de la testosterona libre en el diagnóstico y seguimiento del cáncer de próstata.” 2016. Web. 08 Dec 2019.

Vancouver:

Regis Plácido L. Valor de la testosterona libre en el diagnóstico y seguimiento del cáncer de próstata. [Internet] [Thesis]. Universitat Autònoma de Barcelona; 2016. [cited 2019 Dec 08]. Available from: http://hdl.handle.net/10803/386533.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Regis Plácido L. Valor de la testosterona libre en el diagnóstico y seguimiento del cáncer de próstata. [Thesis]. Universitat Autònoma de Barcelona; 2016. Available from: http://hdl.handle.net/10803/386533

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

22. Aguilera i Roig, Javier. Ácido tranexámico en cirugía protésica de rodilla.

Degree: Departament de Cirurgia, 2015, Universitat Autònoma de Barcelona

URL: http://hdl.handle.net/10803/322820

► This doctoral thesis entitled: "tranexamic acid in knee replacement surgery" of the candidate Xavier Aguilera Roig, is the epitome of a series of clinical research… (more)

▼ This doctoral thesis entitled: "tranexamic acid in knee replacement surgery" of the candidate Xavier Aguilera Roig, is the epitome of a series of clinical research studies, including 7 publications over 4 years, from 2011 to 2015. Total knee replacement is one of the most common surgeries in orthopaedic surgery. In the last decade there has been a significant increase in the number of implanted prosthesis as a result of increased life expectancy and patient’s age and the increase of young patients undergoing this surgery. All this helped by the improvement in the techniques used, acquiring more experience by surgeons and increased implant survival. However, it is not a free process complication. The main objective in the early postoperative surgery of total knee arthroplasty is the fast patient recovery. The clinical outcome of total knee arthroplasty depends among other factors of the total knee arthroplasty component’s design and material, the correct placement of the implants, of the preoperative patient status and also the control of the postoperative bleeding. There is no doubt that the blood lost is one of the factors that influence its immediate result. The postoperative bleeding in knee arthroplasty varies between 800 to 2000 mL, being necessary in many cases allogeneic blood transfusions. The publications presented here seek to obtain evidence about the efficacy and safety of tranexamic acid as an antifibrinolytic drug, in patients undergoing total knee arthroplasty. The importance of these publications is the need to develop an adequate control of bleeding and increase the quality and safety of the surgical patient while reducing the cost of these surgical procedures. The optimal control of postoperative bleeding prevents own prosthetic surgery complications and complications directly related to anemia and allogeneic blood transfusions. The common hypothesis of the different publications presented in this memory is "tranexamic acid reduces postoperative bleeding in patients undergoing total knee arthroplasty, without associated complications." And the main aim of the thesis was to evaluate the efficacy and safety of tranexamic acid in relation to postoperative bleeding compared to standard treatment of routine hemostasis and other drugs in total knee arthroplasty. The publications submitted is concluded that tranexamic acid has been shown to be effective and safe for controlling bleeding in surgery after total knee arthroplasty. Also, the memory raises future studies to complement their line of research. Advisors/Committee Members: [email protected] (authoremail), true (authoremailshow), Videla i Cés, Sebastià (director), Lamas Gómez, Claudia (director), Monllau i Garcia, Joan Carles (director), true (authorsendemail).

Subjects/Keywords: Àcid tranexamic; Ácido tranexámico; Tranexamic acid; Pròtesi de genoll; Prótesis de rodilla; Knee arthroplasty; Ciències de la Salut; 617

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APA (6^th Edition):

Aguilera i Roig, J. (2015). Ácido tranexámico en cirugía protésica de rodilla. (Thesis). Universitat Autònoma de Barcelona. Retrieved from http://hdl.handle.net/10803/322820

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Aguilera i Roig, Javier. “Ácido tranexámico en cirugía protésica de rodilla.” 2015. Thesis, Universitat Autònoma de Barcelona. Accessed December 08, 2019. http://hdl.handle.net/10803/322820.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Aguilera i Roig, Javier. “Ácido tranexámico en cirugía protésica de rodilla.” 2015. Web. 08 Dec 2019.

Vancouver:

Aguilera i Roig J. Ácido tranexámico en cirugía protésica de rodilla. [Internet] [Thesis]. Universitat Autònoma de Barcelona; 2015. [cited 2019 Dec 08]. Available from: http://hdl.handle.net/10803/322820.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Aguilera i Roig J. Ácido tranexámico en cirugía protésica de rodilla. [Thesis]. Universitat Autònoma de Barcelona; 2015. Available from: http://hdl.handle.net/10803/322820

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universitat Autònoma de Barcelona

23. Bellmunt Fontanet, Àngela María. Papel de los exosomas en la comunicación entre las células tumorales y los macrófagos en el carcinoma laríngeo.

Degree: Departament de Cirurgia, 2018, Universitat Autònoma de Barcelona

URL: http://hdl.handle.net/10803/665638

► Laryngeal squamous cell carcinoma is currently the sixth cancer diagnosed in the world and still carries a high mortality. It is therefore necessary to continue… (more)

▼ Laryngeal squamous cell carcinoma is currently the sixth cancer diagnosed in the world and still carries a high mortality. It is therefore necessary to continue investigating new and effective therapies. The tumor microenvironment of laryngeal cancer has been recognized to play an essential role in the tumoral process. It is composed by tumor cells, immune cells, fibroblasts, mesenchymal cells and macrophages. This thesis focuses on the involvement of tumor associated macrophages in tumor growth, angiogenesis and immune response evasion. All these features have been associated with poor prognosis in cancer. This study provides knowledge about the interactions that take place between laryngeal tumor cell and tumor associated macrophages, describing some of the immunobiological mechanisms that occur in laryngeal cancer and that provide a pro-tumoral microenvironment. In the introduction we review and update the anatomy and epidemiological features and provide an overview of some of the microenvirontmental mechanisms involved in the carcinogenesis, focusing on tumor associated macrophages. We have carried out experimental models to study the immunosuppression in head and neck squamous cell carcinoma and the intercellular mechanisms that potentially mediate this process in laryngeal cancer. The main hypothesis of this study is that exosomes are involved in the pathophysiology of laryngeal cancer modulating the communication between macrophages and tumor cells. We have carried out in vitro experiments to determine which effects in the tumor cell are due to the presence of macrophages and which of them would be mediated by exosomes. Additionally, we have evaluated signaling pathways involved in that process. Throughout this experimental work we have concluded that macrophages induce an increased migration in laryngeal tumor cells through exosomes. Reciprocally, the tumor cell induces a pro-tumoral phenotype to macrophages, in part, also through exosomes. Communication mediated by exosome between tumor cell and macrophages alters the expression of PD-1 / PD-L1 proteins in macrophage and tumor cell respectively. We hypothesize that this induction would be mediated by the nuclear signaling pathway STAT3, which would be activated by exosomes derived from macrophages. In conclusion, this data suggest that exosomes may be a potential target for future monitoring and tailoring treatments of laryngeal cancer. Advisors/Committee Members: [email protected] (authoremail), true (authoremailshow), Lorente Guerrero, Juan (director), Closa, Daniel, 1961- (director).

Subjects/Keywords: Càncer de laringe; Cáncer de laringe; Laryngeal cancer; Exosomes; Exosomas; Exosomes; STAT3; Ciències de la Salut; 61

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APA (6^th Edition):

Bellmunt Fontanet, �. M. (2018). Papel de los exosomas en la comunicación entre las células tumorales y los macrófagos en el carcinoma laríngeo. (Thesis). Universitat Autònoma de Barcelona. Retrieved from http://hdl.handle.net/10803/665638

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Bellmunt Fontanet, Àngela María. “Papel de los exosomas en la comunicación entre las células tumorales y los macrófagos en el carcinoma laríngeo.” 2018. Thesis, Universitat Autònoma de Barcelona. Accessed December 08, 2019. http://hdl.handle.net/10803/665638.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Bellmunt Fontanet, Àngela María. “Papel de los exosomas en la comunicación entre las células tumorales y los macrófagos en el carcinoma laríngeo.” 2018. Web. 08 Dec 2019.

Vancouver:

Bellmunt Fontanet �M. Papel de los exosomas en la comunicación entre las células tumorales y los macrófagos en el carcinoma laríngeo. [Internet] [Thesis]. Universitat Autònoma de Barcelona; 2018. [cited 2019 Dec 08]. Available from: http://hdl.handle.net/10803/665638.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Bellmunt Fontanet �M. Papel de los exosomas en la comunicación entre las células tumorales y los macrófagos en el carcinoma laríngeo. [Thesis]. Universitat Autònoma de Barcelona; 2018. Available from: http://hdl.handle.net/10803/665638

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universitat Autònoma de Barcelona

24. Pérez Vélez, Javier Eduardo. Análisis comparativo entre simpaticotomía y clipaje del nervio simpático en la hiperhidrosis y el rubor facial en un programa de cirugía mayor ambulatoria.

Degree: Departament de Cirurgia, 2012, Universitat Autònoma de Barcelona

URL: http://hdl.handle.net/10803/129571

► Introduction Until now, the surgical treatment for hyperhidrosis/facial blushing has been approached using one of two techniques: sympathectomy (excision of the ganglia along the sympathetic… (more)

▼ Introduction Until now, the surgical treatment for hyperhidrosis/facial blushing has been approached using one of two techniques: sympathectomy (excision of the ganglia along the sympathetic nerve chain) and/or sympathicotomy (transection of the sympathetic nerve chain), this last method being the current gold standard for surgical treatment. Sympathetic chain clipping has also been shown to be a safe and effective alternative. Material and Method: We carried out a retrospective analysis of a prospective, descriptive, and comparative database of patients that underwent video-assisted thoracic surgery for hyperhidrosis/facial blushing in the Hospital Universitario Germans Trias i Pujol, between January 2007 and December 2009. We analysed variables involving patient demographics and the surgical procedure for the overall sample and for sub-groups based on the surgical technique employed (clipping vs sympathetic chain transection). Results: We evaluated 163 procedures in 82 patients, the majority of which were for palmar/plantar hyperhidrosis (31.7%), palmar/axillary/plantar hyperhidrosis (31.7%), palmar/axillary hyperhidrosis (9.8%), axillary hyperhidrosis (7.3%), palmar hyperhidrosis (6.8%), facial blushing (2.4%), and other combinations. Clipping was used in 72 procedures (44.2%) and sympathetic chain transection in 91 (55.8%). There were no differences between groups in terms of age, sex, or surgical risk. One ganglion was interrupted in 59.8% of patients and two in 40.2%. Moderate/severe compensatory sweating occurred in 27.9% of cases (9 transections and 3 clipping). Clips were removed in one patient due to severe compensatory sweating. We analysed the following risk factors for compensatory sweating: age, sex, body mass index (BMI), and level and number of ganglia operated on; in the univariate and multivariate analyses, only age resulted as a risk factor regardless of the surgical technique used. Fewer complications occurred in the clipping group (11.1%). Patient satisfaction was 87% in the transection group and 86.1% in the clipping group. Conclusions: Video-assisted thoracoscopic sympathetic nerve surgery in a major ambulatory surgery unit is a safe procedure. Both methods yielded excellent results with comparable complication rates and patient satisfaction. There were no significant differences in terms of compensatory sweating. Advisors/Committee Members: [email protected] (authoremail), true (authoremailshow), Astudillo Pombo, Julio (director), Oller Sales, Benjamín (director), Casas García, Irma (director), true (authorsendemail).

Subjects/Keywords: Hiperhidrosis; Clipaje; Ciències de la Salut; 617

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APA (6^th Edition):

Pérez Vélez, J. E. (2012). Análisis comparativo entre simpaticotomía y clipaje del nervio simpático en la hiperhidrosis y el rubor facial en un programa de cirugía mayor ambulatoria. (Thesis). Universitat Autònoma de Barcelona. Retrieved from http://hdl.handle.net/10803/129571

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Pérez Vélez, Javier Eduardo. “Análisis comparativo entre simpaticotomía y clipaje del nervio simpático en la hiperhidrosis y el rubor facial en un programa de cirugía mayor ambulatoria.” 2012. Thesis, Universitat Autònoma de Barcelona. Accessed December 08, 2019. http://hdl.handle.net/10803/129571.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Pérez Vélez, Javier Eduardo. “Análisis comparativo entre simpaticotomía y clipaje del nervio simpático en la hiperhidrosis y el rubor facial en un programa de cirugía mayor ambulatoria.” 2012. Web. 08 Dec 2019.

Vancouver:

Pérez Vélez JE. Análisis comparativo entre simpaticotomía y clipaje del nervio simpático en la hiperhidrosis y el rubor facial en un programa de cirugía mayor ambulatoria. [Internet] [Thesis]. Universitat Autònoma de Barcelona; 2012. [cited 2019 Dec 08]. Available from: http://hdl.handle.net/10803/129571.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Pérez Vélez JE. Análisis comparativo entre simpaticotomía y clipaje del nervio simpático en la hiperhidrosis y el rubor facial en un programa de cirugía mayor ambulatoria. [Thesis]. Universitat Autònoma de Barcelona; 2012. Available from: http://hdl.handle.net/10803/129571

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universitat de València

25. Moreno Puigdollers, Ignacio. Oxido nítrico inhalado en donantes y receptores de trasplante pulmonar. Prevención de la disfunción primaria del injerto.

Degree: Departament de Cirurgia, 2009, Universitat de València

URL: http://hdl.handle.net/10803/9613

► Introduction and objectives: Lung transplantation (LT) is now a valid therapeutic option for patients with end-stage pulmonary parenchymatous and vascular diseases when other treatments have… (more)

▼ Introduction and objectives: Lung transplantation (LT) is now a valid therapeutic option for patients with end-stage pulmonary parenchymatous and vascular diseases when other treatments have failed. Primary graft dysfunction (PGD) secondary to ischaemic/reperfusion damage is responsible for significant morbidity and is the principal cause of early death following lung reimplantation. This inflammatory reaction can be reduced by administering inhaled nitric oxide (iNO), because of its immunomodulatory effects. Our objective was to verify whether administering iNO to LT receptors modifies blood and bronchoalveolar lavage (BAL) levels of interleukin (IL) 6, 8, 10, TNF and whether it is related to PGD. a prospective study was conducted on all lung transplantations performed between June 2005 and November 2007. Material and Methods: Severe PGD (ISHLT, International Society of Heart and Lung Transplantation, grade II) was defined as: 1) Radiographic infiltrates during the first 72 hours after transplantation. 2) PaO2/FiO2 ratio of less than 200 in the first 72 hours post-operatively. 3) No other cause for dysfunction. In the iNO group (INOmax® from INO Therapeutics Inc., Clinton, New Jersey), the gas was administered at 10 ppm from the start of LT until 48 hours after graft reperfusion. BAL and peripheral arterial blood samples were taken prior to reimplantation (baseline level) and at 12, 24, and 48 after reperfusion. Results: In the 49 transplantations studied (100%), elevated IL-6, 8, 10 and TNF in BAL and blood was observed in comparison with baseline levels (p < 0.0001). The iNO treatment group showed a lower incidence of PGD compared with the control group (26% vs 60%), (p = 0,011). Significant differences (p<0.05) were observed in the iNO group, with lower IL levels at 12 and 24 hours in blood and BAL. Discussion: Our lung transplant patients developed an inflammatory response following reimplantation with systemic elevation of IL-6 and significant local elevation of IL-8 within the first few hours, especially in those who developed PGD. In our series, iNO appeared to modulate the inflammatory response by reducing interleukin concentrations in the group that was given iNO, and this reduction was related to a lower incidence of PGD. Advisors/Committee Members: [email protected] (authoremail), false (authoremailshow), Vicente Guillen, Rosario (director).

Subjects/Keywords: Facultat de Medicina i Odontologia; 616.2; 617

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APA (6^th Edition):

Moreno Puigdollers, I. (2009). Oxido nítrico inhalado en donantes y receptores de trasplante pulmonar. Prevención de la disfunción primaria del injerto. (Thesis). Universitat de València. Retrieved from http://hdl.handle.net/10803/9613

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Moreno Puigdollers, Ignacio. “Oxido nítrico inhalado en donantes y receptores de trasplante pulmonar. Prevención de la disfunción primaria del injerto.” 2009. Thesis, Universitat de València. Accessed December 08, 2019. http://hdl.handle.net/10803/9613.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Moreno Puigdollers, Ignacio. “Oxido nítrico inhalado en donantes y receptores de trasplante pulmonar. Prevención de la disfunción primaria del injerto.” 2009. Web. 08 Dec 2019.

Vancouver:

Moreno Puigdollers I. Oxido nítrico inhalado en donantes y receptores de trasplante pulmonar. Prevención de la disfunción primaria del injerto. [Internet] [Thesis]. Universitat de València; 2009. [cited 2019 Dec 08]. Available from: http://hdl.handle.net/10803/9613.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Moreno Puigdollers I. Oxido nítrico inhalado en donantes y receptores de trasplante pulmonar. Prevención de la disfunción primaria del injerto. [Thesis]. Universitat de València; 2009. Available from: http://hdl.handle.net/10803/9613

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universitat de València

26. Belinchón de Diego, Antonio. Historia natural de la enfermedad de Meniere.

Degree: Departament de Cirurgia, 2009, Universitat de València

URL: http://hdl.handle.net/10803/9614

► INTRODUCTION. A constant question in any disease, for the doctor and for the patient, is to know which can be its evolution. Medical science has… (more)

▼ INTRODUCTION. A constant question in any disease, for the doctor and for the patient, is to know which can be its evolution. Medical science has solved this problem by means of a precise diagnosis of the type of disease and the subsequent observation of its evolution in many cases. The diagnostic criteria on which this investigation is based are those of The American Academy of Otolaryngology of 1995 for the diagnosis of the Definitive EM. The number of studies on the natural history of Meniere´s disease are scarce. The principal reason for this are: 1. The absence of homogeneity in the diagnosis. 2. Series with few patients. 3. Studies with too short follow-ups. 4. The lack of uniformity in the criteria for the evaluation of its evolution. OBJECTIVE. Provided that we posses a important number of patients, (considering the small frequency of the process), controlled periodically from 1 to 31 years by means of a computer program MEN designed especially for this study. We evaluated parameters of the evolution of the disease both clinical and auditive exploration, throughout time, to define its natural history. We also will study the evolution depending on that the cases are uni or bilateral and if a surgical treatment (neurectomy, chemical or surgical labyrinthectomy, descompression of endolynphatic sac) takes place. MATERIAL AND METHODS. A group of 237 patients is studied from 1 to 31 years. All the patients included come from the otolaryngology service (unit of otoneurology) of the University Hospital "La Fe". We evaluate the clinical data of the Meniere´s disease: Age, gender, the time elapsed between the beginning of the disease and the assistance by the specialist, the evolution of the appearance of the symptoms (vertigo, hearing loss and tinnitus), the Tumarkin crisis, the degree of disability along the evolution, the frequency of the crisis of vertigo throughout the time, behaviour of the disease the year previous to the first visit, evolution of the hearing, the study of the bilateral cases, correlation between vertigo and hearing loss, the surgical treatments performed and its repercussion on the vertigo crises. Advisors/Committee Members: [email protected] (authoremail), false (authoremailshow), Pérez Garriguez, Herminio (director), Morera Pérez, Constantino (director).

Subjects/Keywords: Facultat de Medicina i Odontologia; 617

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APA (6^th Edition):

Belinchón de Diego, A. (2009). Historia natural de la enfermedad de Meniere. (Thesis). Universitat de València. Retrieved from http://hdl.handle.net/10803/9614

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Belinchón de Diego, Antonio. “Historia natural de la enfermedad de Meniere.” 2009. Thesis, Universitat de València. Accessed December 08, 2019. http://hdl.handle.net/10803/9614.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Belinchón de Diego, Antonio. “Historia natural de la enfermedad de Meniere.” 2009. Web. 08 Dec 2019.

Vancouver:

Belinchón de Diego A. Historia natural de la enfermedad de Meniere. [Internet] [Thesis]. Universitat de València; 2009. [cited 2019 Dec 08]. Available from: http://hdl.handle.net/10803/9614.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Belinchón de Diego A. Historia natural de la enfermedad de Meniere. [Thesis]. Universitat de València; 2009. Available from: http://hdl.handle.net/10803/9614

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universitat de València

27. Renovell Ferrer, Pablo. Factores de riesgo y trombofilia en la necrosis idiopática de cabezal femoral.

Degree: Departament de Cirurgia, 2009, Universitat de València

URL: http://hdl.handle.net/10803/9616

► Although many etiopathological theories and multiple causes have been suggested for idiopathic osteonecrosis of the femoral head, the physiopathology of this illness it has not… (more)

▼ Although many etiopathological theories and multiple causes have been suggested for idiopathic osteonecrosis of the femoral head, the physiopathology of this illness it has not been clarified yet. In the last few years some studies relate the appearance of the illness with coagulation disorders in these patients. Due to the development of sequencing genetic technics, it has also been possible to associate the illness with different genetic polymorphisms of enzymes implicated in osteonecrosis physiopathology. In the present study, 60 patients with diagnosis of idiopathic osteonecrosis of the hip were compared with 60 controls free of this disease that have been matched by sex and age. Antecedents, weith, height, waist diameter and serum analysis including lipids, glucose and trombophilia parameters were collected. It has been analized the genetic polymorphisms of MTHFR (1298C>T), SERPINE1 (4G/5G) of PAI-I, NOS3 (786 C>T), NOS3 (582+244 B>A), VEGFA (634 G>C), LPA and F5. It is found significant statistically differences between the two groups in thromboembolic disease background, patients in treatment of hypertension and diabetes, smoke and alcohol intake habits, corticoesteriods administration, prevalence of patients with Metabolic Syndrome criteria, trombophilia parameters and antithrombin levels. There are significant statistically differences too in prevalence of homozygosity for the mutant eNOS allele (TT) on the T-786C eNOS polymorphism, that have been associated previously with decrease of nitric oxide production. The conclusion is that the interaction between the different risk factors in idiopathic osteonecrosis of the hip is hight. The integration of all them on the same model allows conclude that glucocorticoid excess use, excessive alcohol intake and the presence of Metabolic Syndrome are independent risk factors for the development of idiopathic osteonecrosis of proximal femur. Trombophilia disorders results marginally significative when it is analized together with all risk factors. Advisors/Committee Members: [email protected] (authoremail), false (authoremailshow), Redón i Mas, Josep (director), Silvestre Muñoz, Antonio (director).

Subjects/Keywords: Facultat de Medicina i Odontologia; 617

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APA (6^th Edition):

Renovell Ferrer, P. (2009). Factores de riesgo y trombofilia en la necrosis idiopática de cabezal femoral. (Thesis). Universitat de València. Retrieved from http://hdl.handle.net/10803/9616

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Renovell Ferrer, Pablo. “Factores de riesgo y trombofilia en la necrosis idiopática de cabezal femoral.” 2009. Thesis, Universitat de València. Accessed December 08, 2019. http://hdl.handle.net/10803/9616.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Renovell Ferrer, Pablo. “Factores de riesgo y trombofilia en la necrosis idiopática de cabezal femoral.” 2009. Web. 08 Dec 2019.

Vancouver:

Renovell Ferrer P. Factores de riesgo y trombofilia en la necrosis idiopática de cabezal femoral. [Internet] [Thesis]. Universitat de València; 2009. [cited 2019 Dec 08]. Available from: http://hdl.handle.net/10803/9616.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Renovell Ferrer P. Factores de riesgo y trombofilia en la necrosis idiopática de cabezal femoral. [Thesis]. Universitat de València; 2009. Available from: http://hdl.handle.net/10803/9616

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universitat de València

28. Ivorra García-Moncó, Purificación. Estudio prospectivo de calidad de vida tras la cirugia del cáncer de recto.

Degree: Departament de Cirurgia, 2009, Universitat de València

URL: http://hdl.handle.net/10803/9618

► Introduction: Rectal cancer treatment implies in most cases making a rectal excision that affects not only the defecatory function but also the sexual and urinary… (more)

▼ Introduction: Rectal cancer treatment implies in most cases making a rectal excision that affects not only the defecatory function but also the sexual and urinary functions and the quality of life of these patients. Objectives: Evaluate pre and postoperative quality of life and defecatory function in rectal cancer patients. Compare quality of life in patients with a colostomy and patients with anastomosis. Patients and methods: This is a prospective study of a rectal cancer population, T4 and M1 patients were excluded; we performed a preoperative and a postoperative evaluation (one year after the surgery) of the quality of life and defecatory function. Parameters analized were: age, gender, TNM stage, anal margin distance, chemoradiotherapy neoadjuvant therapy and surgical technique. Results: Our study included 85 patients; we found no differences in pre and postoperative defecatory function and quality of life, although postoperative sexual dysfunction was significantly higher in male patients. Patients with total mesorectal excision (TME) suffered more anal incontinence, more pain and more sexual dysfunction than patients with subtotal mesorectal excision (STME); when we excluded patients with neoadjuvant therapy the difference in pain and sexual dysfunction remained. When we compared patients with intersphincteric and conventional resection we found higher rates of obstructive defecation after conventional resection. Patients with colostomy had a worse quality of life that patients with anastomosis, they also had worse results concerning physical function, loss of appetite, nausea and vomiting, loss of weight and body image perception. When we compared patients with TME and anastomosis and patients with colostomy we only found that patients with colostomy had more loss of appetite, more loss of weight and a worse body image perception. Conclusions: Pre and postoperative results in defecatory function and quality of life after rectal cancer surgery are quite similar. However, male patients experience more sexual dysfunction after surgery. Patients with colostomy have worse quality of life that patients with STME and anastomosis and similar quality of life that patientes with TME and anastomosis. In both cases body image perception is worse in the colostomy group. Patients with TME have more sexual dysfunction than patients with STME. Advisors/Committee Members: [email protected] (authoremail), false (authoremailshow), Minguez Pérez, Miguel (director), García-Granero Ximénez, Eduardo (director), Lledó Matoses, Salvador (director).

Subjects/Keywords: Facultat de Medicina i Odontologia; 616; 617

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Ivorra García-Moncó, P. (2009). Estudio prospectivo de calidad de vida tras la cirugia del cáncer de recto. (Thesis). Universitat de València. Retrieved from http://hdl.handle.net/10803/9618

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Ivorra García-Moncó, Purificación. “Estudio prospectivo de calidad de vida tras la cirugia del cáncer de recto.” 2009. Thesis, Universitat de València. Accessed December 08, 2019. http://hdl.handle.net/10803/9618.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Ivorra García-Moncó, Purificación. “Estudio prospectivo de calidad de vida tras la cirugia del cáncer de recto.” 2009. Web. 08 Dec 2019.

Vancouver:

Ivorra García-Moncó P. Estudio prospectivo de calidad de vida tras la cirugia del cáncer de recto. [Internet] [Thesis]. Universitat de València; 2009. [cited 2019 Dec 08]. Available from: http://hdl.handle.net/10803/9618.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Ivorra García-Moncó P. Estudio prospectivo de calidad de vida tras la cirugia del cáncer de recto. [Thesis]. Universitat de València; 2009. Available from: http://hdl.handle.net/10803/9618

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universitat Autònoma de Barcelona

29. Calsina Juscafresa, Laura. Aplicabilitat de les corbes cusum en el control de qualitat i en l’avaluació d’efectes d’aprenentatge en cirurgia endovascular.

Degree: Departament de Cirurgia, 2015, Universitat Autònoma de Barcelona

URL: http://hdl.handle.net/10803/317967

► Quality of care and learning effect surveillance are two unavoidable responsibilities during acquirement and maintenance of new therapeutic techniques. CUSUM curves methodology have been successfully… (more)

▼ Quality of care and learning effect surveillance are two unavoidable responsibilities during acquirement and maintenance of new therapeutic techniques. CUSUM curves methodology have been successfully used for these two purposes. The aim of this study was to evaluate, applying CUSUM curves, the quality of care and the learning effect, associated with the introduction and development of intention to treat endovascular procedures in aorto-iliac, femoropopliteal and renal artery occlusive disease, as well as evaluating, the efficacy and safety of the endovascular diagnostic and therapeutic procedures performed through a brachial approach. MATERIAL AND METHODS: Firstly, consecutive patients with aorto-iliac, femoropopliteal or renal artery occlusive disease with endovascular therapeutic indication, treated by vascular surgeons in the Hospital del Mar of Barcelona between 2003 and 2009, of those were registered, as quality indicators, inability to cross the lesion, peri- and post-procedural complications and significant residual stenosis or occlusion at 1 month. Secondly, consecutive patients in which endovascular procedures through a brachial approach were performed, treated by vascular surgeons in the Hospital del Mar of Barcelona between 2003 and 2010, of those were registered, as quality indicators, all procedural complications. Data collected were transferred to adjusted CUSUM curves according to the average published morbidity given for each arterial territory and for brachial approach. Graphic ascending inflections were later evaluated with sub analysis for each quality indicator and Chi test. RESULTS: Between 2003-2009, 553 consecutive patients, scheduled for endovascular intervention of aorto-iliac (n = 131, 23.7%), femoropopliteal (n = 142, 25.7%) and renal artery (n = 128, 23.1%) occlusive disease were treated. 3 PTA (percutaneous transluminal angioplasty) and 117 PTA + stent; 8 PTA and 119 PTA + stent and 109 PTA + stent, were respectively performed. The percentages associated with peri- and post-procedural complications were 14.5%, 9.2% and 1.6%; failure to cross the lesion, 6.9%, 10.6% and 1.6%; and significant residual stenosis or occlusion at 1 month, 0.8%, 4.9% and 2.3%, respectively. Aorto-iliac CUSUM curve showed two upward inflections at the beginning and the end of the period, both associated with peri- and post-procedural complications (p = 0.034) and the last one also due to failure to cross the lesion (p = 0.033). Femoro-popliteal CUSUM curve moved progressively upward during all the period, initially related to peri- and post-procedural complications and later to failure to cross the lesion (p = 0.005). Renal CUSUM curve didn't show any upward inflection during the analysed period. When it comes to the procedures performed via brachial approach, all but one procedure were completed according to their scheduled intention. The overall complication rate was 5.5% (5 pseudoaneurysms (2.1%), 4 transient ischemic attack (1.7%), 3 brachial artery thromboses (1.3%) and 1 cardiac tamponade (0.4%).… Advisors/Committee Members: [email protected] (authoremail), true (authoremailshow), Clará Velasco, Albert (director), Grande Posa, Luis (director), true (authorsendemail).

Subjects/Keywords: Cusum; Corba d'aprenentatge; Curva de aprendizaje; Learning curve; Control de qualitat; Control de calidad; Quality of care; Ciències de la Salut; 617

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Calsina Juscafresa, L. (2015). Aplicabilitat de les corbes cusum en el control de qualitat i en l’avaluació d’efectes d’aprenentatge en cirurgia endovascular. (Thesis). Universitat Autònoma de Barcelona. Retrieved from http://hdl.handle.net/10803/317967

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Calsina Juscafresa, Laura. “Aplicabilitat de les corbes cusum en el control de qualitat i en l’avaluació d’efectes d’aprenentatge en cirurgia endovascular.” 2015. Thesis, Universitat Autònoma de Barcelona. Accessed December 08, 2019. http://hdl.handle.net/10803/317967.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Calsina Juscafresa, Laura. “Aplicabilitat de les corbes cusum en el control de qualitat i en l’avaluació d’efectes d’aprenentatge en cirurgia endovascular.” 2015. Web. 08 Dec 2019.

Vancouver:

Calsina Juscafresa L. Aplicabilitat de les corbes cusum en el control de qualitat i en l’avaluació d’efectes d’aprenentatge en cirurgia endovascular. [Internet] [Thesis]. Universitat Autònoma de Barcelona; 2015. [cited 2019 Dec 08]. Available from: http://hdl.handle.net/10803/317967.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Calsina Juscafresa L. Aplicabilitat de les corbes cusum en el control de qualitat i en l’avaluació d’efectes d’aprenentatge en cirurgia endovascular. [Thesis]. Universitat Autònoma de Barcelona; 2015. Available from: http://hdl.handle.net/10803/317967

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universitat Autònoma de Barcelona

30. Juan Beltrán, Júlia de. Propuesta de clasificación (pTNM) de los pacientes con carcinoma de cabeza y cuello en función de la presencia de ruptura capsular.

Degree: Departament de Cirurgia, 2011, Universitat Autònoma de Barcelona

URL: http://hdl.handle.net/10803/79092

► INTRODUCTION Most studies show that capsular spread (R +) in lymph nodes of patients with squamous cell carcinoma of head and neck has big significant… (more)

▼ INTRODUCTION Most studies show that capsular spread (R +) in lymph nodes of patients with squamous cell carcinoma of head and neck has big significant prognostic importance. A study was conducted in our center in order to evaluate the prognostic capability of the presence of capsular spread in neck dissections of patients with squamous cell carcinoma of head and neck and to evaluate the usefulness of including this information in the (pTNM) histopathological classification methods. MATERIAL AND METHODS We studied 1190 patients diagnosed of carcinoma of the oral cavity, oro-hypopharynx, larynx, synchronous tumors and metastatic squamous cell carcinoma without known primary tumor between January 1985 and June 2007, treated with neck dissection. We described the clinical characteristics and treatment performed on the primary tumour and nodal areas. Patients were classified according to prognostic variables with a technique that uses recursive partitioning (RPA). RPA and pN classifications were compared. RESULTS 28% of patients had capsular spread. The five year survival rate for pN0 patients was 86%, for pN +/R- patients was 63% and for pN+/R+ patients was 30%. The presence of lymph node metastasis with capsular spread significantly worsened the possibility of regional and distant disease control. We obtained a classification of our patients from the study of survival rate with the RPA method, which included information on: histological nodal status, the presence or absence of capsular spread and the number of lymph nodes with rupture. We calculated the survival rate for the stages of the new classification and we compared survival curves with those obtained from the classical pN classification (TNM). We observed that the RPA classification is better when we compared them visually and also objectively using the criteria described by Groome et al. CONCLUSIONS In patients with squamous cell carcinoma of head and neck, R + is a first order prognostic predictor factor, therefore, we propose a modification of the conventional pTNM classification to improve its prognostic capacity. Advisors/Committee Members: [email protected] (authoremail), true (authoremailshow), León i Vintró, Xavier (director), Quer, Miquel (director), true (authorsendemail).

Subjects/Keywords: Ruptura capsular; Carcinoma cabeza y cuello; Propuesta de clasificación; Ciències de la Salut; 617

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Juan Beltrán, J. d. (2011). Propuesta de clasificación (pTNM) de los pacientes con carcinoma de cabeza y cuello en función de la presencia de ruptura capsular. (Thesis). Universitat Autònoma de Barcelona. Retrieved from http://hdl.handle.net/10803/79092

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Juan Beltrán, Júlia de. “Propuesta de clasificación (pTNM) de los pacientes con carcinoma de cabeza y cuello en función de la presencia de ruptura capsular.” 2011. Thesis, Universitat Autònoma de Barcelona. Accessed December 08, 2019. http://hdl.handle.net/10803/79092.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Juan Beltrán, Júlia de. “Propuesta de clasificación (pTNM) de los pacientes con carcinoma de cabeza y cuello en función de la presencia de ruptura capsular.” 2011. Web. 08 Dec 2019.

Vancouver:

Juan Beltrán Jd. Propuesta de clasificación (pTNM) de los pacientes con carcinoma de cabeza y cuello en función de la presencia de ruptura capsular. [Internet] [Thesis]. Universitat Autònoma de Barcelona; 2011. [cited 2019 Dec 08]. Available from: http://hdl.handle.net/10803/79092.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Juan Beltrán Jd. Propuesta de clasificación (pTNM) de los pacientes con carcinoma de cabeza y cuello en función de la presencia de ruptura capsular. [Thesis]. Universitat Autònoma de Barcelona; 2011. Available from: http://hdl.handle.net/10803/79092

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Open Access Theses and Dissertations