You searched for subject:(memory consolidation).
Showing records 1 – 30 of
139 total matches.
◁ [1] [2] [3] [4] [5] ▶
Rutgers University
1.
Kanta Chantzi, Vasiliki, 1990-.
The role of gamma oscillations in the modulation of memory consolidation by emotions.
Degree: PhD, Behavioral and Neural Sciences, 2019, Rutgers University
URL: https://rucore.libraries.rutgers.edu/rutgers-lib/61650/ 
► Our everyday experiences, even for mundane events, can form long-lasting memories. While newly formed memories are labile at first, with time they may become permanent…
(more)
▼ Our everyday experiences, even for mundane events, can form long-lasting memories. While newly formed memories are labile at first, with time they may become permanent and resistant to forgetting. This process is called memory consolidation. For declarative memories, consolidation is thought to involve interactions between the neocortex and hippocampus during offline states such as sleep. Besides strengthening with time, memory consolidation is also influenced by emotional arousal. The facilitating effect of emotions on consolidation is mediated by the basolateral amygdala (BLA) and its strong projections to both the hippocampus and neocortex. In contrast to the extensive investigations of the electrophysiological mechanisms supporting systems consolidation between the hippocampus and neocortex, there has not been a comparable advancement in our understanding of the BLA’s role. However, what is known is that the BLA generates robust gamma oscillations during emotional arousal, which can facilitate interregional interactions. In order to provide a unified understanding of memory consolidation, I examined how the consolidation of emotional experiences affects the interactions between the BLA, hippocampus and medial prefrontal cortex (mPFC), a neocortical area linked to consolidation. In particular, I studied how gamma-related activity is affected after emotional learning. I then directly tested whether gamma oscillations in the BLA support consolidation, by using real-time optogenetic manipulation of these oscillations in the post-training consolidation period. My results show that gamma oscillations mediate the emotional facilitation of memory consolidation.
Advisors/Committee Members: Pare, Denis (chair), Polack, Pierre-Olivier (internal member), Koos, Tibor (internal member), Mena-Segovia, Juan (internal member), LaLumiere, Ryan (outside member).
Subjects/Keywords: Memory consolidation
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Kanta Chantzi, Vasiliki, 1. (2019). The role of gamma oscillations in the modulation of memory consolidation by emotions. (Doctoral Dissertation). Rutgers University. Retrieved from https://rucore.libraries.rutgers.edu/rutgers-lib/61650/
Chicago Manual of Style (16th Edition):
Kanta Chantzi, Vasiliki, 1990-. “The role of gamma oscillations in the modulation of memory consolidation by emotions.” 2019. Doctoral Dissertation, Rutgers University. Accessed March 07, 2021.
https://rucore.libraries.rutgers.edu/rutgers-lib/61650/.
MLA Handbook (7th Edition):
Kanta Chantzi, Vasiliki, 1990-. “The role of gamma oscillations in the modulation of memory consolidation by emotions.” 2019. Web. 07 Mar 2021.
Vancouver:
Kanta Chantzi, Vasiliki 1. The role of gamma oscillations in the modulation of memory consolidation by emotions. [Internet] [Doctoral dissertation]. Rutgers University; 2019. [cited 2021 Mar 07].
Available from: https://rucore.libraries.rutgers.edu/rutgers-lib/61650/.
Council of Science Editors:
Kanta Chantzi, Vasiliki 1. The role of gamma oscillations in the modulation of memory consolidation by emotions. [Doctoral Dissertation]. Rutgers University; 2019. Available from: https://rucore.libraries.rutgers.edu/rutgers-lib/61650/
University of Edinburgh
2.
McIlroy, Lucy.
Age-related Impairments in Long-Term Retention of Verbal Material: A Problem of Accelerated Forgetting or a Deficit in Acquisition?.
Degree: 2009, University of Edinburgh
URL: http://hdl.handle.net/1842/3588
► Several diverging theories exist as to whether young adults share the same analogous difficulties as healthy older adults on tests of verbal acquisition and retention…
(more)
▼ Several diverging theories exist as to whether young adults share the same analogous difficulties as healthy older adults on tests of verbal acquisition and retention of novel stimuli. Research suggests older adults may incur higher processing demands when instructed to remember lists containing unrelated words, compared to semantically categorised word lists, and over retention intervals. Through manipulation of learning criterion and list information, the current study attempted to delineate the contribution of age-related deficits to long-term forgetting. This longitudinal study assessed performance on four word lists each comprised of fifteen nouns, modified from the CVLT and RAVLT. Recall scores were measured over delay-intervals of 30minutes, 24hours and 7days, to test for reliable heterogeneity and critical periods in forgetting rates between young (18-25 years, n=20) and old adults (60-80 years, n=20). By matching subjects on acquisition for half the lists, this test aimed to decompose whether ageing reflects an encoding or
consolidation deficit. Our findings indicate that: (a) older adults incur significantly more rapid forgetting of novel stimuli over time, providing evidence of reliable variability in forgetting slopes across the life span, (b) older adults incur greater difficulty in acquiring novel words, and (c) young and old adults do not differ in the benefit experienced from semantic relatedness of word lists. These results support Huppert & Kopelman’s (1989) findings of a mild acquisition deficit but a more robust impairment in subsequent retention processes and are consistent with a
consolidation account of forgetting.
Advisors/Committee Members: Abrahams, Sharon.
Subjects/Keywords: Memory; Ageing; Forgetting; Acquisition; Consolidation
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
McIlroy, L. (2009). Age-related Impairments in Long-Term Retention of Verbal Material: A Problem of Accelerated Forgetting or a Deficit in Acquisition?. (Thesis). University of Edinburgh. Retrieved from http://hdl.handle.net/1842/3588
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
McIlroy, Lucy. “Age-related Impairments in Long-Term Retention of Verbal Material: A Problem of Accelerated Forgetting or a Deficit in Acquisition?.” 2009. Thesis, University of Edinburgh. Accessed March 07, 2021.
http://hdl.handle.net/1842/3588.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
McIlroy, Lucy. “Age-related Impairments in Long-Term Retention of Verbal Material: A Problem of Accelerated Forgetting or a Deficit in Acquisition?.” 2009. Web. 07 Mar 2021.
Vancouver:
McIlroy L. Age-related Impairments in Long-Term Retention of Verbal Material: A Problem of Accelerated Forgetting or a Deficit in Acquisition?. [Internet] [Thesis]. University of Edinburgh; 2009. [cited 2021 Mar 07].
Available from: http://hdl.handle.net/1842/3588.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
McIlroy L. Age-related Impairments in Long-Term Retention of Verbal Material: A Problem of Accelerated Forgetting or a Deficit in Acquisition?. [Thesis]. University of Edinburgh; 2009. Available from: http://hdl.handle.net/1842/3588
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
University of Edinburgh
3.
Tse, Dorothy.
Schema and memory consolidation.
Degree: PhD, 2011, University of Edinburgh
URL: http://hdl.handle.net/1842/5545
► The traditional view of systems memory consolidation is that it is a gradual process that takes place over days or weeks. Within this approach, the…
(more)
▼ The traditional view of systems memory consolidation is that it is a gradual process that takes place over days or weeks. Within this approach, the hippocampus (HPC) is thought to be involved in the rapid encoding of specific events, whilst neocortex is thought to be involved in slow learning. An idea posited recently is that systems consolidation can occur rapidly if an appropriate “schema” into which the new information can be incorporated has been previously created. Using a hippocampaldependent paradigm, rats were trained to learn a schema involving 6 flavour-place paired-associates (PAs). Once the schema was acquired, relevant new information then became assimilated into extra-hippocampal regions and rapidly became hippocampal-independent. Building upon this foundation and the PAs schema paradigm, this thesis has explored several aspects of the neurobiology of schemas in animals. The first part of the thesis examined the importance of a relevant schema in new information processing. Rats were trained in both a consistent and inconsistent schema. In the consistent schema, rats could learn new PAs in a single trial; however, in the inconsistent schema, rats failed to learn the new PAs as they had not established an appropriate schema that could facilitate rapid learning. The second part of the thesis investigated the role of hippocampal NMDA receptors and dopamine receptors during encoding of new PAs. Bilateral hippocampal infusion of either the NMDA receptor antagonist D-AP5 or the D1/D5 dopamine receptor antagonist SCH23390 before encoding of new PAs resulted in impaired memory tested at 24 hr. This result suggests that the encoding of new PAs is dependent upon NMDA receptors in the HPC and also that dopamine is involved in the modulation of encoding new PAs. The final chapters of the thesis attempted to identify the extrahippocampal regions in which these new PAs are integrated with the schema during encoding. To identify the regions that may be involved, immediate early genes (Zif268 and Arc) were used. In a group of cortical structures, including the prelimbic cortex, there was significantly higher Zif268 and Arc expression when encoding 2 new PAs compared to the reactivation of previously learned (original) PAs or the encoding of 6 new PAs. These findings indicate that the prelimbic cortex may be critical for rapid assimilation of new information into a pre-existing schema. Finally, the last experiment in the thesis investigated this finding using bilateral microinfusions of either the AMPA receptor antagonist CNQX or the NMDA receptor antagonist D-AP5 into the prelimbic cortex. Infusions of CNQX and D-AP5 resulted in poor learning of the new PAs in the schema task. This indicates that parallel encoding of new PAs occurred in the prelimbic cortex and the HPC. The experimental results presented in this thesis suggest that the prelimbic cortex, in particular, plays a crucial role along with the HPC during encoding of new information in rapid memory formation.
Subjects/Keywords: 612.8; schema; memory consolidation
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Tse, D. (2011). Schema and memory consolidation. (Doctoral Dissertation). University of Edinburgh. Retrieved from http://hdl.handle.net/1842/5545
Chicago Manual of Style (16th Edition):
Tse, Dorothy. “Schema and memory consolidation.” 2011. Doctoral Dissertation, University of Edinburgh. Accessed March 07, 2021.
http://hdl.handle.net/1842/5545.
MLA Handbook (7th Edition):
Tse, Dorothy. “Schema and memory consolidation.” 2011. Web. 07 Mar 2021.
Vancouver:
Tse D. Schema and memory consolidation. [Internet] [Doctoral dissertation]. University of Edinburgh; 2011. [cited 2021 Mar 07].
Available from: http://hdl.handle.net/1842/5545.
Council of Science Editors:
Tse D. Schema and memory consolidation. [Doctoral Dissertation]. University of Edinburgh; 2011. Available from: http://hdl.handle.net/1842/5545
San Jose State University
4.
Amy, David.
Effects of Caffeine Administered During Consolidation on Veridical and False Memory.
Degree: MA, Psychology, 2018, San Jose State University
URL: https://doi.org/10.31979/etd.cy6s-636z
;
https://scholarworks.sjsu.edu/etd_theses/4927
► Caffeine is used by many people on a daily basis to enhance wakefulness and cognition, yet the effects of caffeine on long term memory…
(more)
▼ Caffeine is used by many people on a daily basis to enhance wakefulness and cognition, yet the effects of caffeine on long term memory remain underspecified. The literature to date reveals mixed findings with respect to caffeine’s effects on both veridical and false memories. Such variability may be due to differences in methodology with respect to the timing of caffeine administration. Many studies administer caffeine at the beginning of the experiment, prior to encoding, making it challenging to determine the cause of changes in memory performance, which may be due to enhanced encoding, consolidation, or retrieval processes, or due to non-memory related enhancements in arousal or attention. Fewer studies have examined the effects of caffeine on memory consolidation, specifically. Here, we used a randomized, double-blind, placebo-controlled design (n = 39) to determine whether caffeine administered during the consolidation phase affects veridical and false memory assessed 24 hours later using the Deese-Roediger-McDermott paradigm. Although the caffeine and control groups both showed high rates of veridical and false memories, we found no differences between groups for either type of memory. This study is an important step towards better understanding the degree to which caffeine affects memory consolidation, and may encourage future researchers to similarly isolate caffeine’s influence on other memory processes.
Subjects/Keywords: caffeine; consolidation; DRM paradigm; false memory; memory
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Amy, D. (2018). Effects of Caffeine Administered During Consolidation on Veridical and False Memory. (Masters Thesis). San Jose State University. Retrieved from https://doi.org/10.31979/etd.cy6s-636z ; https://scholarworks.sjsu.edu/etd_theses/4927
Chicago Manual of Style (16th Edition):
Amy, David. “Effects of Caffeine Administered During Consolidation on Veridical and False Memory.” 2018. Masters Thesis, San Jose State University. Accessed March 07, 2021.
https://doi.org/10.31979/etd.cy6s-636z ; https://scholarworks.sjsu.edu/etd_theses/4927.
MLA Handbook (7th Edition):
Amy, David. “Effects of Caffeine Administered During Consolidation on Veridical and False Memory.” 2018. Web. 07 Mar 2021.
Vancouver:
Amy D. Effects of Caffeine Administered During Consolidation on Veridical and False Memory. [Internet] [Masters thesis]. San Jose State University; 2018. [cited 2021 Mar 07].
Available from: https://doi.org/10.31979/etd.cy6s-636z ; https://scholarworks.sjsu.edu/etd_theses/4927.
Council of Science Editors:
Amy D. Effects of Caffeine Administered During Consolidation on Veridical and False Memory. [Masters Thesis]. San Jose State University; 2018. Available from: https://doi.org/10.31979/etd.cy6s-636z ; https://scholarworks.sjsu.edu/etd_theses/4927
Brock University
5.
MacDonald, Kevin.
The Role of Sleep in the Selective Reconsolidation of Declarative Memories
.
Degree: Department of Psychology, 2014, Brock University
URL: http://hdl.handle.net/10464/5854
► While sleep has been shown to be involved in memory consolidation and the selective enhancement of newly acquired memories of future relevance (Wilhelm, et al.,…
(more)
▼ While sleep has been shown to be involved in memory consolidation and the selective
enhancement of newly acquired memories of future relevance (Wilhelm, et al., 2011),
limited research has investigated the role of sleep or future relevance in processes of
memory reconsolidation. The current research employed a list-method directed forgetting
procedure in which participants learned two lists of syllable pairs on Night 1 and received
directed forgetting instructions on Night 2. On Night 2, one group (Labile; n = 15)
received a memory reactivation treatment consisting of reminders designed to return
memories of the learned lists to a labile state. A second group (Stable, n = 16) received
similar reminders designed to leave memories of the learned lists in their stable state. No
differences in forgetting were found across the two lists or groups. However, a negative
correlation between frontal delta (1 – 4 Hz) electroencephalographic (EEG) power during
Early Stage 2 non-rapid eye movement (NREM) sleep and forgetting of to-beremembered
material was found exclusively in the Labile group (r = -.61, p < .05).
Further, central theta (4 – 8 Hz ) EEG power during rapid eye movement (REM) sleep
was found to correlate with directed forgetting exclusively in the Labile group (r = .81, p
< .001) and total forgetting in the Stable group (r = .50, p < .05). These observed
relationships support the proposed hypothesis suggesting that sleep processes are
involved in the reconsolidation of labile memories, and that this reconsolidation may be
selective for memories of future relevance. A role for sleep in the beneficial reprocessing
of memories through the selective reconsolidation of labile memories in NREM sleep and
the weakening of memories in REM sleep is discussed.
Subjects/Keywords: Sleep;
Memory Consolidation;
Memory Reconsolidation;
EEG
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
MacDonald, K. (2014). The Role of Sleep in the Selective Reconsolidation of Declarative Memories
. (Thesis). Brock University. Retrieved from http://hdl.handle.net/10464/5854
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
MacDonald, Kevin. “The Role of Sleep in the Selective Reconsolidation of Declarative Memories
.” 2014. Thesis, Brock University. Accessed March 07, 2021.
http://hdl.handle.net/10464/5854.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
MacDonald, Kevin. “The Role of Sleep in the Selective Reconsolidation of Declarative Memories
.” 2014. Web. 07 Mar 2021.
Vancouver:
MacDonald K. The Role of Sleep in the Selective Reconsolidation of Declarative Memories
. [Internet] [Thesis]. Brock University; 2014. [cited 2021 Mar 07].
Available from: http://hdl.handle.net/10464/5854.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
MacDonald K. The Role of Sleep in the Selective Reconsolidation of Declarative Memories
. [Thesis]. Brock University; 2014. Available from: http://hdl.handle.net/10464/5854
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
6.
Todorova, Ralitsa.
Profils d'activité neurale lors d'événements oscillatoires soutendant la consolidation des souvenirs dépendant de l'hippocampe : Neuronal activity patterns during oscillatory events underlying the consolidation of hippocampus dependent memories.
Degree: Docteur es, Neurosciences, 2018, Paris Sciences et Lettres (ComUE)
URL: http://www.theses.fr/2018PSLET043
► Le stockage à long terme des souvenirs épisodiques requiert la formation de la mémoire pendant l'expérience d'éveil ainsi que la consolidation de la mémoire, un…
(more)
▼ Le stockage à long terme des souvenirs épisodiques requiert la formation de la mémoire pendant l'expérience d'éveil ainsi que la
consolidation de la mémoire, un processus de renforcement de la mémoire qui a lieu pendant le sommeil. L'encodage rapide des traces mnésiques a lieu dans l'hippocampe pendant l'éveil. Pendant le sommeil, les traces mnésiques de l'hippocampe sont « rejouées » pendant les ondulations – de brefs motifs oscillatoires hippocampiques (50-150 ms) à haute fréquence associés à une activité synchrone élevée. Les bouffées d'activité synchrone des neurones de l'hippocampe pendant les ondulations font d'eux des acteurs clés dans la
consolidation de la mémoire des systèmes – le processus de communication des mémoires vers le néocortex pour un stockage à long terme.L'activité corticale dans le sommeil est dominée par l'oscillation lente – l'alternance synchrone des neurones corticaux entre un état dépolarisé (état HAUT) associé à des niveaux élevés d'activité endogène, et un état bref (~200ms) hyperpolarisé (état BAS) lorsque les neurones restent silencieux. Les états BAS sont accompagnés de grandes déviations du potentiel de champ local – ondes delta, tandis que les états HAUTS sont associés à une activité élevée et des fuseaux thalamocorticaux, deux processus pouvant entraîner une plasticité synaptique. On pense que la
consolidation de la mémoire des systèmes implique une coordination entre les rythmes hippocampiques et corticaux – notamment, les ondulations hippocampiques précèdent (~130ms) les ondes delta corticales, qui sont ensuite suivies par des fuseaux thalamocorticaux.Pour vérifier si ce couplage temporel entraîne une
consolidation de la mémoire, nous avons déclenché des ondes delta corticales suite à des ondulations hippocampiques afin d'améliorer la cooccurrence d'événements ondulation-delta couplés. Cela a augmenté la
consolidation de la mémoire et la performance du rat sur une tâche de mémoire spatiale, et a entraîné une réorganisation des réseaux corticaux préfrontaux suite à des ondes delta induites ainsi qu'une réponse accrue du cortex préfrontal à la tâche le lendemain. De manière cruciale, ces améliorations n'ont pas été observées lorsqu'un retard (160-240 ms) a été introduit en plus du couplage endogène, indiquant que la stabilisation des traces mnésiques nécessite une interaction très fine entre les ondulations et les ondes delta.Comment l'interruption de l'activité corticale par des périodes de silence généralisées pendant les ondes delta peut-elle sous-tendre la
consolidation de la mémoire lorsqu'elle se produit précisément entre le transfert d'informations (réactivation hippocampique) et la plasticité du réseau (état HAUT) ? Contrairement à un principe généralement accepté, nous avons constaté que les ondes delta ne sont pas des périodes de silence complet, et que l'activité résiduelle n'est pas un simple bruit neuronal. Au lieu de cela, nous avons montré que les cellules corticales émettent des « delta spikes » pendant les ondes delta en réponse à la réactivation transitoire…
Advisors/Committee Members: Zugaro, Michaël (thesis director).
Subjects/Keywords: Mémoire; Consolidation; Hippocampe; Électrophysiologie; Memory; Consolidation; Hippocampus; Electrophysiology; 570
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Todorova, R. (2018). Profils d'activité neurale lors d'événements oscillatoires soutendant la consolidation des souvenirs dépendant de l'hippocampe : Neuronal activity patterns during oscillatory events underlying the consolidation of hippocampus dependent memories. (Doctoral Dissertation). Paris Sciences et Lettres (ComUE). Retrieved from http://www.theses.fr/2018PSLET043
Chicago Manual of Style (16th Edition):
Todorova, Ralitsa. “Profils d'activité neurale lors d'événements oscillatoires soutendant la consolidation des souvenirs dépendant de l'hippocampe : Neuronal activity patterns during oscillatory events underlying the consolidation of hippocampus dependent memories.” 2018. Doctoral Dissertation, Paris Sciences et Lettres (ComUE). Accessed March 07, 2021.
http://www.theses.fr/2018PSLET043.
MLA Handbook (7th Edition):
Todorova, Ralitsa. “Profils d'activité neurale lors d'événements oscillatoires soutendant la consolidation des souvenirs dépendant de l'hippocampe : Neuronal activity patterns during oscillatory events underlying the consolidation of hippocampus dependent memories.” 2018. Web. 07 Mar 2021.
Vancouver:
Todorova R. Profils d'activité neurale lors d'événements oscillatoires soutendant la consolidation des souvenirs dépendant de l'hippocampe : Neuronal activity patterns during oscillatory events underlying the consolidation of hippocampus dependent memories. [Internet] [Doctoral dissertation]. Paris Sciences et Lettres (ComUE); 2018. [cited 2021 Mar 07].
Available from: http://www.theses.fr/2018PSLET043.
Council of Science Editors:
Todorova R. Profils d'activité neurale lors d'événements oscillatoires soutendant la consolidation des souvenirs dépendant de l'hippocampe : Neuronal activity patterns during oscillatory events underlying the consolidation of hippocampus dependent memories. [Doctoral Dissertation]. Paris Sciences et Lettres (ComUE); 2018. Available from: http://www.theses.fr/2018PSLET043
University of Toronto
7.
Santoro, Adam.
A Computational Model of Systems Consolidation: Optimizing Memory-guided Behavior using Abstracted Hippocampal and Cortical Networks.
Degree: PhD, 2015, University of Toronto
URL: http://hdl.handle.net/1807/71318
► Learning is not a isolated event, as nearly every encoding event occurs on a backdrop of previous knowledge. This idea is tightly intertwined with that…
(more)
▼ Learning is not a isolated event, as nearly every encoding event occurs on a backdrop of previous knowledge. This idea is tightly intertwined with that of
memory consolidation, which is a concept that describes the fate of memories post-encoding. After the brain encodes some episode, the encoded information undergoes a transition from hippocampal dependence to cortical dependence. Contemporary
memory consolidation theories emphasize the nature of the computations that occur during this transfer, pointing to the extraction of statistical regularities, or the formation of schemas, as critical components. The work presented in this thesis analyzes
memory consolidation from a computational perspective. Firstly, it describes necessary conditions for the extraction of statistical regularities across individually learned episodes, demonstrating that a
consolidation-like mechanism best captures this phenomenon. Next, it probes a possible purpose of
memory consolidation within a two-
memory system, showing that a joint hippocampal and cortical network optimizes
memory-guided behavior in a foraging-like task. Finally, some anatomical evidence is explored within the context of a major tenet of
memory consolidation, namely the slow changes in interconnectivity between distributed neocortical regions during the
consolidation period. The work presented in this thesis constitutes a highly comprehensive model of
memory consolidation and provides a basis for further inquiry into the nuances of
consolidation phenomena, such as the effects of
memory interference, neurogenesis, and forgetting.
Advisors/Committee Members: Frankland, Paul, Medical Science.
Subjects/Keywords: computational model; episodic memory; hippocampus; learning; memory consolidation; semantic memory; 0317
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Santoro, A. (2015). A Computational Model of Systems Consolidation: Optimizing Memory-guided Behavior using Abstracted Hippocampal and Cortical Networks. (Doctoral Dissertation). University of Toronto. Retrieved from http://hdl.handle.net/1807/71318
Chicago Manual of Style (16th Edition):
Santoro, Adam. “A Computational Model of Systems Consolidation: Optimizing Memory-guided Behavior using Abstracted Hippocampal and Cortical Networks.” 2015. Doctoral Dissertation, University of Toronto. Accessed March 07, 2021.
http://hdl.handle.net/1807/71318.
MLA Handbook (7th Edition):
Santoro, Adam. “A Computational Model of Systems Consolidation: Optimizing Memory-guided Behavior using Abstracted Hippocampal and Cortical Networks.” 2015. Web. 07 Mar 2021.
Vancouver:
Santoro A. A Computational Model of Systems Consolidation: Optimizing Memory-guided Behavior using Abstracted Hippocampal and Cortical Networks. [Internet] [Doctoral dissertation]. University of Toronto; 2015. [cited 2021 Mar 07].
Available from: http://hdl.handle.net/1807/71318.
Council of Science Editors:
Santoro A. A Computational Model of Systems Consolidation: Optimizing Memory-guided Behavior using Abstracted Hippocampal and Cortical Networks. [Doctoral Dissertation]. University of Toronto; 2015. Available from: http://hdl.handle.net/1807/71318
Texas State University – San Marcos
8.
Hawkins, Christopher A.
The Selective Consolidation of Declarative Memories.
Degree: MA, Psychological Research, 2016, Texas State University – San Marcos
URL: https://digital.library.txstate.edu/handle/10877/6123
► During sleep, recently learned memories are stabilized through a process known as consolidation. This process does not uniformly preserve all recent experiences; some memories fade,…
(more)
▼ During sleep, recently learned memories are stabilized through a process known as
consolidation. This process does not uniformly preserve all recent experiences; some memories fade, whereas others become resistant to disruption and appear to last indefinitely. One possibility consistent with recent results is that
memory processing during sleep may reflect an adaptive mechanism for evaluating recent experiences and relating them to future goals. The present study was designed to further test this possibility, by determining whether event-related potentials (ERPs) associated with goal- consistent memories change more across a night of sleep than ERPs associated with goal- irrelevant memories. Participants completed a
memory task involving two sessions separated by a 24-hour delay. In the initial session, participants studied a series of images appearing in one of eight locations on a screen and their
memory was immediately tested for the image locations. Half of the images were money-related (goal-relevant) while the other half were office supply (goal-irrelevant) images. After two study-test cycles were complete, each participant was informed that when they came back the next day they would complete one final
memory test, and that if their
memory for the locations associated with money images improved the following day, they would receive an extra five dollars. The instruction was meant to bias them by making the money-related images in line with their goal of increasing financial gains. ERP’s were recorded for three time components (FN400, LPC, LFE) during the final test on day 1 (baseline) and the test on day 2 (delayed). Results revealed no difference in
memory change from the baseline to the delayed test between the money-related and office supply images. However, ERP results revealed that there was a greater increase in the late positive component (500 – 800 ms) over the posterior regions from the baseline to the delayed test. This result suggests that
memory for locations associated with money-related images may have been preferentially consolidated compared with office supply images. Additionally, the FN400 showed increased negativity at the delayed test compared to the baseline test over frontal regions, suggesting that familiarity increased over time for both image types. Finally, the LFE showed an increased positivity in the central ROI consistent with behavioral results suggesting that money-related images required more effortful processing to accurately retrieve.
Advisors/Committee Members: Westerberg, Carmen E. (advisor), Deason, Rebecca (committee member), Kelemen, William (committee member), Trujillo, Logan (committee member).
Subjects/Keywords: Memory; Selective; Consolidation; Declarative; LPC; Hawkins; Memory; Memory – Psychological aspects
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Hawkins, C. A. (2016). The Selective Consolidation of Declarative Memories. (Masters Thesis). Texas State University – San Marcos. Retrieved from https://digital.library.txstate.edu/handle/10877/6123
Chicago Manual of Style (16th Edition):
Hawkins, Christopher A. “The Selective Consolidation of Declarative Memories.” 2016. Masters Thesis, Texas State University – San Marcos. Accessed March 07, 2021.
https://digital.library.txstate.edu/handle/10877/6123.
MLA Handbook (7th Edition):
Hawkins, Christopher A. “The Selective Consolidation of Declarative Memories.” 2016. Web. 07 Mar 2021.
Vancouver:
Hawkins CA. The Selective Consolidation of Declarative Memories. [Internet] [Masters thesis]. Texas State University – San Marcos; 2016. [cited 2021 Mar 07].
Available from: https://digital.library.txstate.edu/handle/10877/6123.
Council of Science Editors:
Hawkins CA. The Selective Consolidation of Declarative Memories. [Masters Thesis]. Texas State University – San Marcos; 2016. Available from: https://digital.library.txstate.edu/handle/10877/6123
Texas A&M University
9.
Kim, Taewon.
Want to Foster New Motor Learning Following High Contextual Interference Practice: Better Consolidate Previous Learning First.
Degree: MS, Kinesiology, 2015, Texas A&M University
URL: http://hdl.handle.net/1969.1/154960
► High contextual interference (CI) practice regimes aid in the retention and transfer of skilled actions. The elaboration perspective, still considered a viable explanation for the…
(more)
▼ High contextual interference (CI) practice regimes aid in the retention and transfer of skilled actions. The elaboration perspective, still considered a viable explanation for the benefit of high CI training, proposes that a richer network of task specific knowledge is developed from random practice thus, affording the learner a variety of ways to retrieve task relevant information during delayed tests. One would expect that new tasks, similar to previously trained exemplars, will be acquired faster and retained with greater success following random as opposed to blocked practice. That is, the presence of a rich
memory network should provide a suitable foundation from which to incorporate new related task knowledge. To examine this prediction subjects practiced three unique motor tasks in either a blocked or random format. Original practice consisted of nine trials for each seven-element motor sequence in a blocked or random schedule. An additional nine trials of practice with the novel motor sequence was experienced by all participants shortly after original training in the Experiment 1. While the typical retention benefit emerged for random practice for the original motor tasks, no practice schedule effect was revealed for new learning. Experiment 2 examined the possibility that increasing the interval between original training and supplemental practice with the novel motor task might benefit from a greater time interval. By increasing this interval from 2–min to 24-hr afforded individuals an opportunity to consolidate the
memory network developed following random or blocked practice. Congruent with Experiment 1 the CI effect emerged in the form of superior retention of the motor tasks acquired via random practice. Moreover, following the longer temporal interval, random practice facilitated the rate at which new task information was used to execute a new skill which was also reflected in superior retention than observed following blocked practice. Interestingly, following
consolidation, both practice schedules exhibited a task-independent benefit when first required to perform the novel task, and offline improvement in performance across a 24-hr interval. These data will be discussed with respect to broader learning benefits from inducing greater CI and the importance of
memory consolidation for motor learning.
Advisors/Committee Members: Wright, David L (advisor), Shea , Charles H (committee member), Geraci, Lisa (committee member).
Subjects/Keywords: Contextual interference; New motor learning; Memory consolidation
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Kim, T. (2015). Want to Foster New Motor Learning Following High Contextual Interference Practice: Better Consolidate Previous Learning First. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/154960
Chicago Manual of Style (16th Edition):
Kim, Taewon. “Want to Foster New Motor Learning Following High Contextual Interference Practice: Better Consolidate Previous Learning First.” 2015. Masters Thesis, Texas A&M University. Accessed March 07, 2021.
http://hdl.handle.net/1969.1/154960.
MLA Handbook (7th Edition):
Kim, Taewon. “Want to Foster New Motor Learning Following High Contextual Interference Practice: Better Consolidate Previous Learning First.” 2015. Web. 07 Mar 2021.
Vancouver:
Kim T. Want to Foster New Motor Learning Following High Contextual Interference Practice: Better Consolidate Previous Learning First. [Internet] [Masters thesis]. Texas A&M University; 2015. [cited 2021 Mar 07].
Available from: http://hdl.handle.net/1969.1/154960.
Council of Science Editors:
Kim T. Want to Foster New Motor Learning Following High Contextual Interference Practice: Better Consolidate Previous Learning First. [Masters Thesis]. Texas A&M University; 2015. Available from: http://hdl.handle.net/1969.1/154960
Lithuanian Academy of Physical Education
10.
Petraitytė,
Rūta.
Motorinių įgūdžių įtvirtinimas nakties metu
asmenims, sergantiems galvos smegenų insultu.
Degree: Master, Nursing, 2011, Lithuanian Academy of Physical Education
URL: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2011~D_20110630_135359-47408
;
► Tyrimo objektas: dieninis ir naktinis motorinių įgūdžių sutvirtinimas. Tyrimo tikslas: nustatyti dieninis ar naktinis motorinių įgūdžių sutvirtinimas yra efektyvesnis. Tyrimo uždaviniai: 1. Nustatyti sveikų tiriamųjų…
(more)
▼ Tyrimo objektas: dieninis ir naktinis
motorinių įgūdžių sutvirtinimas. Tyrimo tikslas: nustatyti dieninis
ar naktinis motorinių įgūdžių sutvirtinimas yra efektyvesnis.
Tyrimo uždaviniai: 1. Nustatyti sveikų tiriamųjų motorinių įgūdžių
įtvirtinimą dienos ir nakties metu. 2. Nustatyti tiriamųjų,
patyrusių insultą motorinių įgūdžių įtvirtinimą dienos ir nakties
metu. 3. Palyginti motorinių įgūdžių įtvirtinimą tarp sveikų ir
tiriamųjų po insulto, dieninio ir naktinio mokymo grupių. Tyrimo
hipotezė: Manome, kad pakenktos rankos judesių sutvirtinamą
teigiamai įtakos miegas. Tyrimo metodai: žmogaus rankų ir kojų
judesių dinaminių parametrų analizatorius DPA-1, anketinė apklausa,
statistika. Išvados: 1. Dienos metu sveikiems tiriamiesiems
nustatytas įtvirtintas abiejų užduočių sutrumpėjęs reakcijos
laikas, bei judesio laiko sutrumpėjimas. O nakties metu papildomai
sutrumpėjo įveiktas kelias ir greitis. 2. Galvos smegenų insultu
sergantiems tiriamiesiems, dienos metu pagerėjo reakcijos laikas.
Nakties metu papildomai pagerėjo standartinės užduoties judesio
laikas ir įtvirtintas variabilios užduoties greitis ir judesio
laikas. 3. Tarp sveikų tiriamųjų dieninio ir naktinio mokymo
grupių, reikšmingo skirtumo nėra. Lyginant insultą patyrusius
tiriamuosius dieninėj grupėj pagerėjo reakcijos laikas, naktinio
mokymo grupėje variabilios užduoties laikas iki taikinio ir
vidutinis greitis.
The object of research: „day time“ learning
and „off-line“ learning. The aim of research: to determine which
kind of learning, „day time“ or „off-line“ learning is more
efficient. The goals of research: 1. To determine the consolidation
of motor skills during the day and night for healthy adults. 2. To
determine the consolidation of motor skills during the day and
night for individuals following stroke. 3. To compare consolidation
of motor skills between healthy subjects and after stroke, daytime
and night-time groups. Hypothesis: individuals following stroke do
benefit from sleep to promote off-line motor learning to their
damaged side. Research methods: analyzer DPA – 1, questionnaire
survey, mathematical statistic. Conclusions: 1. During the day,
healthy subjects of both the tasks laid down in the shorter
reaction time and movement time shortening. And at night, in
addition, shorter trajectory and speed. 2. Subjects with stroke
during the day improved response time. At night an additional
improvement in the standard task of motion time and established
variabilis task speed and movement time. 3. Between healthy subject
daytime and night-time training groups, there is no significant
difference. Comparing subjects following stroke, daytime testing
group improved response time of night-time testing group improved
variabilis task target time and average
speed.
Advisors/Committee Members: Kriščiūnas, Aleksandras (Master’s degree committee chair), Žiliukas, Geriuldas (Master’s degree committee member), Dudonienė, Vilma (Master’s degree committee member), Krutulytė, Gražina (Master’s degree committee member), Gorinienė, Galinda (Master’s degree committee member), Vaitauskienė, Vida (Master’s degree session secretary), Skurvydas, Albertas (Master’s thesis supervisor), Bacevičienė, Rasa (Master’s thesis reviewer).
Subjects/Keywords: Miegas; Atmintis; Konsolidacija; Sleep; Memory; Consolidation
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Petraitytė,
Rūta. (2011). Motorinių įgūdžių įtvirtinimas nakties metu
asmenims, sergantiems galvos smegenų insultu. (Masters Thesis). Lithuanian Academy of Physical Education. Retrieved from http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2011~D_20110630_135359-47408 ;
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
Chicago Manual of Style (16th Edition):
Petraitytė,
Rūta. “Motorinių įgūdžių įtvirtinimas nakties metu
asmenims, sergantiems galvos smegenų insultu.” 2011. Masters Thesis, Lithuanian Academy of Physical Education. Accessed March 07, 2021.
http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2011~D_20110630_135359-47408 ;.
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
MLA Handbook (7th Edition):
Petraitytė,
Rūta. “Motorinių įgūdžių įtvirtinimas nakties metu
asmenims, sergantiems galvos smegenų insultu.” 2011. Web. 07 Mar 2021.
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
Vancouver:
Petraitytė,
Rūta. Motorinių įgūdžių įtvirtinimas nakties metu
asmenims, sergantiems galvos smegenų insultu. [Internet] [Masters thesis]. Lithuanian Academy of Physical Education; 2011. [cited 2021 Mar 07].
Available from: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2011~D_20110630_135359-47408 ;.
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
Council of Science Editors:
Petraitytė,
Rūta. Motorinių įgūdžių įtvirtinimas nakties metu
asmenims, sergantiems galvos smegenų insultu. [Masters Thesis]. Lithuanian Academy of Physical Education; 2011. Available from: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2011~D_20110630_135359-47408 ;
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
University of Houston
11.
-1295-195X.
The Slow Rate of Visual Working Memory Consolidation Is a Structural Limit.
Degree: MA, Psychology, 2020, University of Houston
URL: http://hdl.handle.net/10657/6661
► Extensive research has focused on the limited storage capacity of working memory (WM), i.e., the maximum amount of information that can be maintained in WM.…
(more)
▼ Extensive research has focused on the limited storage capacity of working
memory (WM), i.e., the maximum amount of information that can be maintained in WM. However, a relatively understudied limitation of WM involves the processing speed by which sensory information can be transformed into a WM representation that is resistant to distraction from ongoing perception and cognition. The speed of this “consolidation” process is the
subject of conflicting results. Researchers have arrived at estimates of the
consolidation time course using distinct paradigms ranging from 25 ms to 1 s, meaning more than an order of magnitude of variability. The extremely large variation in WM
consolidation speed estimates across measurement approaches motivated the current work’s goal of determining whether
consolidation speed is under strategic control or is a stable structural constraint of WM encoding. Here, the slower (1 s) measurement of WM
consolidation of visually-presented verbal stimuli (i.e., letters) was replicated by using retroactive interference (RI; Nieuwenstein & Wyble, 2014)—essentially, measuring how long it takes after a WM sample array is presented for the representation in WM to no longer be vulnerable to distraction by performing a speeded second task (T2). Then, the RI results were extended to more standard visual WM stimuli (i.e., color patches). Further, slow
consolidation was obtained regardless of the relative prioritization of WM encoding vs. T2, supporting the structural account. However, no RI was obtained when T2 was unspeeded. Finally, a sensorimotor decision and motor response to T2 were required to obtain RI. Given that RI was robust to varying WM probes, WM stimuli, and that slow
consolidation was obtained regardless of strategic demands, the present study supports the structural account of WM
consolidation.
Advisors/Committee Members: Tamber-Rosenau, Benjamin J. (advisor), Cirino, Paul T. (committee member), Yoshida, Hanako (committee member).
Subjects/Keywords: visual working memory; consolidation rate; retroactive interference
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
-1295-195X. (2020). The Slow Rate of Visual Working Memory Consolidation Is a Structural Limit. (Masters Thesis). University of Houston. Retrieved from http://hdl.handle.net/10657/6661
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
Chicago Manual of Style (16th Edition):
-1295-195X. “The Slow Rate of Visual Working Memory Consolidation Is a Structural Limit.” 2020. Masters Thesis, University of Houston. Accessed March 07, 2021.
http://hdl.handle.net/10657/6661.
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
MLA Handbook (7th Edition):
-1295-195X. “The Slow Rate of Visual Working Memory Consolidation Is a Structural Limit.” 2020. Web. 07 Mar 2021.
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
Vancouver:
-1295-195X. The Slow Rate of Visual Working Memory Consolidation Is a Structural Limit. [Internet] [Masters thesis]. University of Houston; 2020. [cited 2021 Mar 07].
Available from: http://hdl.handle.net/10657/6661.
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
Council of Science Editors:
-1295-195X. The Slow Rate of Visual Working Memory Consolidation Is a Structural Limit. [Masters Thesis]. University of Houston; 2020. Available from: http://hdl.handle.net/10657/6661
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
University of Manchester
12.
Roberts, Jenna.
Do the electrophysiological correlates of recognition
memory change with time?.
Degree: 2013, University of Manchester
URL: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:185557
► Jenna RobertsThe University of Manchester, Doctor of PhilosophyAbstractDo the electrophysiological correlates of recognition memory change with time?1st October 2012The aim of this PhD thesis was…
(more)
▼ Jenna RobertsThe University of Manchester, Doctor
of PhilosophyAbstractDo the electrophysiological correlates of
recognition
memory change with time?1st October 2012The aim of this
PhD thesis was to explore the way in which recognition
memory
changes over time and the impact this has on event related
potentials (ERPs) recorded during recognition. An emerging body of
fMRI and animal work has started to suggest that changes to the
neural basis of
memory can be observed after intervals in the order
of days and weeks. Although much research has examined the ERP
correlates of recent recognition, there has been little attempt to
compare this to remote recognition. This gap in the literature is
investigated in the present PhD thesis over five ERP and two
behavioural experiments. The first set of experiments investigated
recognition success i.e. the subjective awareness that a stimulus
has been encountered before. Previous work has associated
familiarity-based recognition with an early midfrontal ERP effect
whereas recollection-based recognition has been linked to a later
onsetting parietal ERP effect. These effects were compared for
recently studied stimuli and stimuli studied 1 week earlier.
Results revealed an attenuation of the late parietal effect. This
quantitative difference suggests that the neural networks
underlying the ERPs for recent and remote recollection remain the
same after a 1 week delay but may be less active after a period of
forgetting. Behavioural work linked this to a drop in strength and
episodic detail for remote recollection. Examining the midfrontal
effect over time produced a more complex pattern of results. The
effect was not reliable in Experiment 1 for remote familiarity
judgments. In follow up experiments, however, midfrontal effects
were reliable for week old memories but were not modulated by
either delay or
memory strength manipulations. These findings do
not permit strong conclusions regarding the way familiarity
memory
and midfrontal ERPs vary over time, other than to say that the
midfrontal effect is not a short lived correlate of recognition
memory. A second set of experiments investigated retrieval
orientation and effort. Retrieval orientation refers to the way in
which participants strategically alter how a
memory cue is
processed based on current task demands. Results showed ERP
differences when remote memories were cued compared to when recent
memories were cued. However, these differences were eliminated when
recent and remote
memory was matched for performance. This finding
indicated that effort required at retrieval rather than
memory age
per se influenced differential cue processing. A follow up
experiment supported this claim but found that participants may
utilise delay information in a very general sense. In this
experiment, ERPs indicated different cue processing when
participants knew the age of the memories they were trying to
retrieve compared to when they did not. Overall, the results
suggest that
memory age does not influence the ERP correlates of
recognition in a…
Advisors/Committee Members: MAYES, ANDREW AR, Mayes, Andrew, Tsivilis, Dimitrios.
Subjects/Keywords: Recognition memory; Consolidation; Event related potentials
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Roberts, J. (2013). Do the electrophysiological correlates of recognition
memory change with time?. (Doctoral Dissertation). University of Manchester. Retrieved from http://www.manchester.ac.uk/escholar/uk-ac-man-scw:185557
Chicago Manual of Style (16th Edition):
Roberts, Jenna. “Do the electrophysiological correlates of recognition
memory change with time?.” 2013. Doctoral Dissertation, University of Manchester. Accessed March 07, 2021.
http://www.manchester.ac.uk/escholar/uk-ac-man-scw:185557.
MLA Handbook (7th Edition):
Roberts, Jenna. “Do the electrophysiological correlates of recognition
memory change with time?.” 2013. Web. 07 Mar 2021.
Vancouver:
Roberts J. Do the electrophysiological correlates of recognition
memory change with time?. [Internet] [Doctoral dissertation]. University of Manchester; 2013. [cited 2021 Mar 07].
Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:185557.
Council of Science Editors:
Roberts J. Do the electrophysiological correlates of recognition
memory change with time?. [Doctoral Dissertation]. University of Manchester; 2013. Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:185557
University of Manchester
13.
Roberts, Jenna.
Do the electrophysiological correlates of recognition
memory change with time?.
Degree: 2013, University of Manchester
URL: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:185051
► AbstractThe aim of this PhD thesis was to explore the way in which recognition memory changes over time. Of particular interest was how forgetting and…
(more)
▼ AbstractThe aim of this PhD thesis was to explore
the way in which recognition
memory changes over time. Of
particular interest was how forgetting and systems level
consolidation processes alter the qualitative nature of recognition
judgments and the impact this has on event related potentials
(ERPs) recorded during recognition. An emerging body of fMRI and
animal work has started to suggest that changes to the neural basis
of
memory can be observed after intervals in the order of days and
weeks. Although much research has examined the ERP correlates of
recent recognition, there has been little attempt to compare this
to remote recognition. This gap in the literature is investigated
in the present PhD thesis over five ERP and two behavioural
experiments. The first set of experiments investigated recognition
success i.e. the subjective awareness that a stimulus has been
encountered before. Previous work has associated familiarity-based
recognition with an early midfrontal ERP effect whereas
recollection-based recognition has been linked to a later onsetting
parietal ERP effect. These effects were compared for recently
studied stimuli and stimuli studied 1 week earlier. Results
revealed an attenuation of the late parietal effect. This
quantitative difference suggests that the neural networks
underlying the ERPs for recent and remote recollection remain the
same after a 1 week delay but may be less active after a period of
forgetting. Behavioural work linked this to a drop in strength and
episodic detail for remote recollection. Examining the midfrontal
effect over time produced a more complex pattern of results. The
effect was not reliable in Experiment 1 for remote familiarity
judgments. In follow up experiments, however, midfrontal effects
were reliable for week old memories but were not modulated by
either delay or
memory strength manipulations. These findings do
not permit strong conclusions regarding the way familiarity
memory
and midfrontal ERPs vary over time, other than to say that the
midfrontal effect is not a short lived correlate of recognition
memory. A second set of experiments investigated how the length of
the delay between study and test impacts on retrieval orientation
and retrieval effort. Retrieval orientation refers to the way in
which participants strategically alter how a
memory cue is
processed based on current task demands. Results showed ERP
differences when remote memories were cued compared to when recent
memories were cued. However, these differences were eliminated when
recent and remote
memory was matched for performance. This finding
indicated that effort required at retrieval rather than
memory age
per se influenced differential cue processing. A follow up
experiment supported this claim but found that participants may
utilise delay information during recognition in a very general
sense. In this experiment, ERPs indicated different cue processing
when participants knew the age of the memories they were trying to
retrieve compared to when they did not. Taken together, the results
suggest…
Advisors/Committee Members: MAYES, ANDREW AR, Mayes, Andrew, Tsivilis, Dimitrios.
Subjects/Keywords: Recognition memory; Consolidation; Event related potential (ERP)
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Roberts, J. (2013). Do the electrophysiological correlates of recognition
memory change with time?. (Doctoral Dissertation). University of Manchester. Retrieved from http://www.manchester.ac.uk/escholar/uk-ac-man-scw:185051
Chicago Manual of Style (16th Edition):
Roberts, Jenna. “Do the electrophysiological correlates of recognition
memory change with time?.” 2013. Doctoral Dissertation, University of Manchester. Accessed March 07, 2021.
http://www.manchester.ac.uk/escholar/uk-ac-man-scw:185051.
MLA Handbook (7th Edition):
Roberts, Jenna. “Do the electrophysiological correlates of recognition
memory change with time?.” 2013. Web. 07 Mar 2021.
Vancouver:
Roberts J. Do the electrophysiological correlates of recognition
memory change with time?. [Internet] [Doctoral dissertation]. University of Manchester; 2013. [cited 2021 Mar 07].
Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:185051.
Council of Science Editors:
Roberts J. Do the electrophysiological correlates of recognition
memory change with time?. [Doctoral Dissertation]. University of Manchester; 2013. Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:185051
University of Toronto
14.
McKelvey, Kyra.
Time-dependent Transformation of Episodic Memories.
Degree: 2013, University of Toronto
URL: http://hdl.handle.net/1807/43226
► Although there has been over a century of research on memory and consolidation, there remains no consensus with respect to the nature of episodic memories…
(more)
▼ Although there has been over a century of research on memory and consolidation, there remains no consensus with respect to the nature of episodic memories over time. This study tests two prominent theories (Standard Consolidation Theory and Trace Transformation Hypothesis), which make opposing predictions as to the quality of remote episodic memory, by investigating memories for film clips. Using true/false questions to test recall immediately, 3 days, and 7 days after encoding, these experiments demonstrate that details (both perceptual and story-line details) are lost, while the gist of memories is maintained over time. These data also suggest that gist and detail may be maintained independently in the brain. These results broaden our understanding of recent and remote memory, and provide support for the transformation view of consolidation. In the future, the transfer of this paradigm to neuroimaging will allow us to investigate the neural basis of episodic memory over time.
MAST
Advisors/Committee Members: Moscovitch, Morris, Psychology.
Subjects/Keywords: Episodic Memory; Transformation; Consolidation; 0633; 0623
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
McKelvey, K. (2013). Time-dependent Transformation of Episodic Memories. (Masters Thesis). University of Toronto. Retrieved from http://hdl.handle.net/1807/43226
Chicago Manual of Style (16th Edition):
McKelvey, Kyra. “Time-dependent Transformation of Episodic Memories.” 2013. Masters Thesis, University of Toronto. Accessed March 07, 2021.
http://hdl.handle.net/1807/43226.
MLA Handbook (7th Edition):
McKelvey, Kyra. “Time-dependent Transformation of Episodic Memories.” 2013. Web. 07 Mar 2021.
Vancouver:
McKelvey K. Time-dependent Transformation of Episodic Memories. [Internet] [Masters thesis]. University of Toronto; 2013. [cited 2021 Mar 07].
Available from: http://hdl.handle.net/1807/43226.
Council of Science Editors:
McKelvey K. Time-dependent Transformation of Episodic Memories. [Masters Thesis]. University of Toronto; 2013. Available from: http://hdl.handle.net/1807/43226
15.
Vinals-Castonguay, Lydia.
Learning, Consolidating, and Generalising Novel Morphology.
Degree: PhD, 2018, University of Cambridge
URL: https://www.repository.cam.ac.uk/handle/1810/274922
► Despite a central role for morphological knowledge in supporting linguistic generalisation, the neural representations supporting its learning remain largely unexplored. This thesis addressed this gap…
(more)
▼ Despite a central role for morphological knowledge in supporting linguistic generalisation, the neural representations supporting its learning remain largely unexplored. This thesis addressed this gap by exploring the role of memory consolidation in morphological learning and generalisation. In three experiments, adult participants learned an artificial language in which stems (e.g. gleet, shiln) combined with plural affixes (e.g. –aff, -opp; gleetaff, shilnopp) to refer to the occupation of multiple male and female characters. Mimicking properties of morphological systems in natural languages, the plurals varied in their phonological consistency/ambiguity and type/token frequency. Two sets of plurals, distinguished by gender, were trained on two successive days. Experiment 1 revealed that generalisation to novel phonologically ambiguous forms measured on the second day showed a greater influence of token frequency for plurals trained on the previous day, suggesting overnight changes in their underlying representations. Experiment 2 examined this effect further by using fMRI to compare the neural representations underlying plurals learned on the day of scanning or on the previous day. Representational Similarity Analysis revealed increased similarity structure among high type frequency plurals and reduced similarity structure among high token frequency plurals following overnight consolidation in the left superior temporal gyrus (STG). These results are consistent with a Complementary Learning Systems (CLS) model in which overnight consolidation supports the development of overlapping representations among several items sharing the same feature (here, an affix; type frequency) and strengthens item-specific representations for frequently occurring items (token frequency). Additionally, connectivity analyses showed that the functional coupling between the left STG and the left dorsolateral prefrontal cortex was weaker for high type frequency plurals and stronger for high token frequency plurals following overnight consolidation. These results suggest that the engagement of prefrontal control processes in retrieving the newly-learned plurals is subject to overnight consolidation and sensitive to the similarity structure underlying the plurals to be retrieved. However, the overnight changes in similarity structure and functional networks observed in Experiment 2 were not mirrored by changes in generalisation to novel forms as were observed in Experiment 1. Experiment 3 aimed to address the discrepancy in consolidation-related changes in generalisation behaviour between the first two experiments. Type/token frequencies were manipulated to bias learning, consolidation, and generalisation towards high token frequency plurals. Despite this manipulation, no consolidation-related changes in generalisation were observed. Findings from all three experiments are interpreted in the context of the CLS model and a role for overnight consolidation in morphological learning and generalisation is discussed.
Subjects/Keywords: Learning; memory consolidation; generalisation; inflectional morphology; fMRI
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Vinals-Castonguay, L. (2018). Learning, Consolidating, and Generalising Novel Morphology. (Doctoral Dissertation). University of Cambridge. Retrieved from https://www.repository.cam.ac.uk/handle/1810/274922
Chicago Manual of Style (16th Edition):
Vinals-Castonguay, Lydia. “Learning, Consolidating, and Generalising Novel Morphology.” 2018. Doctoral Dissertation, University of Cambridge. Accessed March 07, 2021.
https://www.repository.cam.ac.uk/handle/1810/274922.
MLA Handbook (7th Edition):
Vinals-Castonguay, Lydia. “Learning, Consolidating, and Generalising Novel Morphology.” 2018. Web. 07 Mar 2021.
Vancouver:
Vinals-Castonguay L. Learning, Consolidating, and Generalising Novel Morphology. [Internet] [Doctoral dissertation]. University of Cambridge; 2018. [cited 2021 Mar 07].
Available from: https://www.repository.cam.ac.uk/handle/1810/274922.
Council of Science Editors:
Vinals-Castonguay L. Learning, Consolidating, and Generalising Novel Morphology. [Doctoral Dissertation]. University of Cambridge; 2018. Available from: https://www.repository.cam.ac.uk/handle/1810/274922
University of Southern California
16.
Kantak, Shailesh S.
Neural substrates of motor memory consolidation: a double
dissociation of primary motor cortex and dorsolateral prefrontal
cortex induced by practice structure.
Degree: PhD, Biokinesiology & Physical Therapy, 2011, University of Southern California
URL: http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll127/id/340348/rec/4375
► Motor practice drives subsequent offline activity within functionally related resting brain networks. Little is known about how offline neural networks are modulated by practice structures…
(more)
▼ Motor practice drives subsequent offline activity
within functionally related resting brain networks. Little is known
about how offline neural networks are modulated by practice
structures known to affect motor skill learning. To investigate the
neural correlates of motor
memory consolidation, we applied 1 Hz
repetitive Transcranial Magnetic Stimulation (rTMS) immediately
after a bout of constant or variable motor practice to disrupt
either primary motor cortex (M1) or dorsolateral prefrontal cortex
(DLPFC), two putative nodes previously shown to be engaged in early
consolidation. Motor learning was assessed the following day
through a performance-based retention test. Immediately after
constant practice, rTMS to M1, but not DLPFC attenuated retention
of the motor skill. In contrast, immediately after variable
practice, rTMS to DLPFC, but not M1 attenuated retention
performance. These findings provide evidence that for motor skills,
the neural substrates of motor
memory consolidation are modulated
by practice structure.
Advisors/Committee Members: Sullivan, Katherine J.Winstein, Carolee J. (Committee Chair), Fisher, Beth (Committee Member), Knowlton, Barbara (Committee Member), Azen, Stanley Paul (Committee Member).
Subjects/Keywords: motor memory consolidation; neural substrates; practice structure
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Kantak, S. S. (2011). Neural substrates of motor memory consolidation: a double
dissociation of primary motor cortex and dorsolateral prefrontal
cortex induced by practice structure. (Doctoral Dissertation). University of Southern California. Retrieved from http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll127/id/340348/rec/4375
Chicago Manual of Style (16th Edition):
Kantak, Shailesh S. “Neural substrates of motor memory consolidation: a double
dissociation of primary motor cortex and dorsolateral prefrontal
cortex induced by practice structure.” 2011. Doctoral Dissertation, University of Southern California. Accessed March 07, 2021.
http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll127/id/340348/rec/4375.
MLA Handbook (7th Edition):
Kantak, Shailesh S. “Neural substrates of motor memory consolidation: a double
dissociation of primary motor cortex and dorsolateral prefrontal
cortex induced by practice structure.” 2011. Web. 07 Mar 2021.
Vancouver:
Kantak SS. Neural substrates of motor memory consolidation: a double
dissociation of primary motor cortex and dorsolateral prefrontal
cortex induced by practice structure. [Internet] [Doctoral dissertation]. University of Southern California; 2011. [cited 2021 Mar 07].
Available from: http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll127/id/340348/rec/4375.
Council of Science Editors:
Kantak SS. Neural substrates of motor memory consolidation: a double
dissociation of primary motor cortex and dorsolateral prefrontal
cortex induced by practice structure. [Doctoral Dissertation]. University of Southern California; 2011. Available from: http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll127/id/340348/rec/4375
Louisiana State University
17.
Evans, Donell DeBacker.
Quizzing and retention in the high school science class.
Degree: MNS, 2013, Louisiana State University
URL: etd-07022013-072304
;
https://digitalcommons.lsu.edu/gradschool_theses/3780
► There is a need to identify educational tools and methods that are easily assimilated into a secondary science education classroom. The use of testing as…
(more)
▼ There is a need to identify educational tools and methods that are easily assimilated into a secondary science education classroom. The use of testing as an educational tool, rather than as a summative assessment only, has emerged as a possible solution. Test-enhanced learning is attributed to the testing effect (Roediger & Karpicke, 2006). The testing effect refers to the higher probability of recalling an item resulting from the act of retrieving the item from memory (testing) versus additional study trials of the item (Craney et al., 2008). A comparison of frequent testing/quizzing versus no quizzing outcomes were studied to determine whether the testing effect has a positive influence on learning gains in a high school science setting. Eighty-eight juniors and seniors enrolled in chemistry (4 sections) and advance placement biology (1 section) classes during the 2012-2013 school year were studied. A within student experimental design was used. Students were pre-tested prior to content coverage. Upon completion of each topic section the students were given quizzes with feedback. The quizzes targeted 50% of the pre-test/post-test material but were not identical in wording. Learning gains for the quizzed material were equivalent to the learning gains for the non-quizzed material in 66% of the instances tested. In 44 % of the individual classes the learning gains were greater for the quizzed condition. For these pooled data, quizzing resulted in greater learning gains in all chapters. For two of the three biology chapters quizzing resulted in greater learning gains. These results indicate that using tests and quizzes as an educational tool can have a positive impact on student learning gains.
Subjects/Keywords: memory consolidation; within design; pedagogy; potentiated learning
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Evans, D. D. (2013). Quizzing and retention in the high school science class. (Masters Thesis). Louisiana State University. Retrieved from etd-07022013-072304 ; https://digitalcommons.lsu.edu/gradschool_theses/3780
Chicago Manual of Style (16th Edition):
Evans, Donell DeBacker. “Quizzing and retention in the high school science class.” 2013. Masters Thesis, Louisiana State University. Accessed March 07, 2021.
etd-07022013-072304 ; https://digitalcommons.lsu.edu/gradschool_theses/3780.
MLA Handbook (7th Edition):
Evans, Donell DeBacker. “Quizzing and retention in the high school science class.” 2013. Web. 07 Mar 2021.
Vancouver:
Evans DD. Quizzing and retention in the high school science class. [Internet] [Masters thesis]. Louisiana State University; 2013. [cited 2021 Mar 07].
Available from: etd-07022013-072304 ; https://digitalcommons.lsu.edu/gradschool_theses/3780.
Council of Science Editors:
Evans DD. Quizzing and retention in the high school science class. [Masters Thesis]. Louisiana State University; 2013. Available from: etd-07022013-072304 ; https://digitalcommons.lsu.edu/gradschool_theses/3780
University of Notre Dame
18.
Enmamuelle Pardilla Delgado.
Does Sleep Influence the Persistence of False Memories
Across Long Delays?</h1>.
Degree: Psychology, 2014, University of Notre Dame
URL: https://curate.nd.edu/show/dn39x061h9d
► While the influence of sleep on memory has a long history, sleep’s role in the formation of false memories is less clear. False memory…
(more)
▼ While the influence of sleep on
memory has a
long history, sleep’s role in the formation of false memories is
less clear. False
memory has been widely studied using the DRM
task. Although technically a false
memory, remembering the gist of
experience is arguably an adaptive process. Recent studies
demonstrate that a period of sleep benefits both true
memory and
gist-based false
memory when compared to a wake period. Over longer
delays (e.g. 1-2 weeks), true
memory tends to deteriorate while
false
memory persists, but it is currently unknown how sleep
influences this pattern. Here we assess how the positioning of
sleep relative to
memory encoding impacts later retention across
longer delays of 24 and 48 hours. Participants encoded 16 DRM lists
in the morning (WAKE 1st Groups) or evening (SLEEP 1st Groups), and
were tested either 24 or 48 hours later at the same time (four
groups). Results show that true
memory was better after sleeping
first, than after waking first. To a lesser extent, sleeping soon
after learning also increased false
memory. A negative correlation
between SWS and false recognition was found, suggesting that SWS
may be detrimental for semantic/gist processing. These findings are
consistent with fuzzy trace theory, so that verbatim (true)
memories are independent from gist (false) memories, and therefore,
sleep can impact them differently.
Advisors/Committee Members: Kathleen Eberhard, Committee Member, Gabriel A. Radvansky, Committee Member, Jessica D. Payne, Committee Chair.
Subjects/Keywords: gist memory; DRM task; gist; false memory; DRM; gist extraction; sleep-dependent consolidation; consolidation
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Delgado, E. P. (2014). Does Sleep Influence the Persistence of False Memories
Across Long Delays?</h1>. (Thesis). University of Notre Dame. Retrieved from https://curate.nd.edu/show/dn39x061h9d
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Delgado, Enmamuelle Pardilla. “Does Sleep Influence the Persistence of False Memories
Across Long Delays?</h1>.” 2014. Thesis, University of Notre Dame. Accessed March 07, 2021.
https://curate.nd.edu/show/dn39x061h9d.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Delgado, Enmamuelle Pardilla. “Does Sleep Influence the Persistence of False Memories
Across Long Delays?</h1>.” 2014. Web. 07 Mar 2021.
Vancouver:
Delgado EP. Does Sleep Influence the Persistence of False Memories
Across Long Delays?</h1>. [Internet] [Thesis]. University of Notre Dame; 2014. [cited 2021 Mar 07].
Available from: https://curate.nd.edu/show/dn39x061h9d.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Delgado EP. Does Sleep Influence the Persistence of False Memories
Across Long Delays?</h1>. [Thesis]. University of Notre Dame; 2014. Available from: https://curate.nd.edu/show/dn39x061h9d
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
19.
Duffau, Céline.
Implication de la connectivité anatomo-fonctionnelle des régions du cortex frontal dans la formation et la consolidation de la mémoire associative olfactive chez le rongeur : Implication of the anatomo-functional connectivity of frontal cortex regions in the formation and consolidation of associative olfactory memory in the rodent.
Degree: Docteur es, Neurosciences, 2019, Bordeaux
URL: http://www.theses.fr/2019BORD0250
► Initialement encodés dans l’hippocampe, les nouveaux souvenirs déclaratifs, aussi appelés engrammes, deviennent progressivement dépendants d’un réseau distribué de neurones corticaux au cours de leur maturation.…
(more)
▼ Initialement encodés dans l’hippocampe, les nouveaux souvenirs déclaratifs, aussi appelés engrammes, deviennent progressivement dépendants d’un réseau distribué de neurones corticaux au cours de leur maturation. Bien que le rôle du cortex dans le stockage de la mémoire ancienne (MA) ait été clairement démontré, plusieurs études montrent que certains réseaux corticaux pourraient être recrutés précocement, dès l’encodage, et participeraient après maturation, au stockage de la trace mnésique. Ceci a notamment été suggéré pour le cortex frontal, dans lequel des changements structuraux et fonctionnels précoces ont été observés, indiquant que la maturation de la trace corticale nécessiterait des renforcements dans la connectivité fonctionnelle entre les différentes structures dépositaires de la trace mnésique. Grâce au marqueur d’activité neuronale c-fos, nous avons étudié l’évolution temporelle, au cours de la
consolidation mnésique, de la connectivité fonctionnelle des régions frontales : le Cortex PréFrontal médian (CPFm), les parties antérieure (CCa) et postérieure (CCp) du Cortex Cingulaire et le Cortex OrbitoFrontal (COF), lesquelles pourraient participer à la maturation de l’engramme. Nous avons comparé l’activité dans ces régions lors du rappel d’une mémoire olfactive associative récente (MR) ou ancienne à l’aide d’une tâche de transmission sociale de préférence alimentaire.Nous avons identifié trois régions corticales clés co-activées lors du rappel de la MA, suggérant qu’elles forment un nœud critique au sein d’un réseau cortical plus vaste, nécessaire à la formation de l’engramme. L’analyse des corrélations interrégionales des activités neuronales révèle que l’activité du CPFm et du COF est corrélée dès le rappel de la MR, bien que leur recrutement soit dépendant de l’âge de la mémoire. Cette connectivité fonctionnelle s’appuie sur une connectivité anatomique unidirectionnelle entre le CPFm et le COF. Par contraste, le CCp est activé uniquement lors du rappel d’une mémoire récente. Par une approche pharmacogénétique, nous avons sélectivement inhibé le CPFm et révélé son implication lors de la phase d’encodage, mais également dans le rappel de la MR et de la MA. L’ensemble de ces résultats suggèrent que bien que le processus de maturation de la trace mnésique au niveau cortical soit spécifique à chaque région, il requiert une connectivité fonctionnelle entre plusieurs régions corticales dont les cinétiques d’activation distinctes mais coordonnées permettent le stockage et l’expression à long terme du souvenir.Des altérations focalisées de cette connectivité, notamment lors du vieillissement, pourraient ralentir le processus d’apprentissage et/ou changer les stratégies d’apprentissage mis en place par l’animal pour résoudre une tâche complexe. À l’aide un test de discrimination spatiale, au cours de huit sessions d’apprentissage dans un labyrinthe radiaire à huit bras sur une large cohorte de souris âgées (22 mois), nous avons pu isoler deux populations : l’une avec une vitesse d’apprentissage similaire à celle…
Advisors/Committee Members: Nicole, Olivier (thesis director).
Subjects/Keywords: Mémoire olfactive associative; Mémoire spatiale; Consolidation mnésique; Cortex frontal; Vieillissement; Associative olfactory memory; Spatial memory; Memory consolidation; Frontal cortex; Aging
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Duffau, C. (2019). Implication de la connectivité anatomo-fonctionnelle des régions du cortex frontal dans la formation et la consolidation de la mémoire associative olfactive chez le rongeur : Implication of the anatomo-functional connectivity of frontal cortex regions in the formation and consolidation of associative olfactory memory in the rodent. (Doctoral Dissertation). Bordeaux. Retrieved from http://www.theses.fr/2019BORD0250
Chicago Manual of Style (16th Edition):
Duffau, Céline. “Implication de la connectivité anatomo-fonctionnelle des régions du cortex frontal dans la formation et la consolidation de la mémoire associative olfactive chez le rongeur : Implication of the anatomo-functional connectivity of frontal cortex regions in the formation and consolidation of associative olfactory memory in the rodent.” 2019. Doctoral Dissertation, Bordeaux. Accessed March 07, 2021.
http://www.theses.fr/2019BORD0250.
MLA Handbook (7th Edition):
Duffau, Céline. “Implication de la connectivité anatomo-fonctionnelle des régions du cortex frontal dans la formation et la consolidation de la mémoire associative olfactive chez le rongeur : Implication of the anatomo-functional connectivity of frontal cortex regions in the formation and consolidation of associative olfactory memory in the rodent.” 2019. Web. 07 Mar 2021.
Vancouver:
Duffau C. Implication de la connectivité anatomo-fonctionnelle des régions du cortex frontal dans la formation et la consolidation de la mémoire associative olfactive chez le rongeur : Implication of the anatomo-functional connectivity of frontal cortex regions in the formation and consolidation of associative olfactory memory in the rodent. [Internet] [Doctoral dissertation]. Bordeaux; 2019. [cited 2021 Mar 07].
Available from: http://www.theses.fr/2019BORD0250.
Council of Science Editors:
Duffau C. Implication de la connectivité anatomo-fonctionnelle des régions du cortex frontal dans la formation et la consolidation de la mémoire associative olfactive chez le rongeur : Implication of the anatomo-functional connectivity of frontal cortex regions in the formation and consolidation of associative olfactory memory in the rodent. [Doctoral Dissertation]. Bordeaux; 2019. Available from: http://www.theses.fr/2019BORD0250
Texas State University – San Marcos
20.
Johnson, McKensey L.
The Effect of Continuous Positive Airway Pressure (CPAP).
Degree: MA, Psychological Research, 2017, Texas State University – San Marcos
URL: https://digital.library.txstate.edu/handle/10877/8768
► Obstructive sleep apnea (OSA) is a clinical sleep disorder that is characterized by frequent pauses in breathing during sleep due to obstructions of the upper…
(more)
▼ Obstructive sleep apnea (OSA) is a clinical sleep disorder that is characterized by frequent pauses in breathing during sleep due to obstructions of the upper airway, and can lead to a range of cardiovascular and neuropsychological deficits, including
memory problems. During sleep, recent memories are actively processed and consolidated into pre-existing knowledge networks.
Consolidation is also discriminatory, such that memories that are relevant for future behavior are enhanced more so than other memories. It is possible that the
memory deficits associated with untreated OSA are due to deficits in
memory consolidation from disrupted sleep. Continuous positive airway pressure (CPAP) is the standard treatment for OSA, and long-term use has been shown to ameliorate the physiological, psychological, and
memory impairments associated with OSA. This study investigated the effect of a single night of CPAP treatment on
memory consolidation. The study included treatment-naïve OSA patients (no-CPAP group) and OSA patients receiving their first night of CPAP treatment (CPAP group). All participants completed two consecutive rounds of study followed by a test for picture- location memories from two categories of objects before a sleep period. In addition, just prior to sleep, all participants were informed that they would complete the
memory test again in the morning and if their
memory for one specific category of objects improved from the evening test they would receive additional compensation. Before the morning test, all participants were informed that, counter to the previous instruction, they would receive the monetary bonus upon improvement in both reward-relevant and reward – irrelevant object categories. There were no differences in
memory accuracy or in
memory change from the evening to the morning test between groups. Furthermore, both groups showed better retention of reward-irrelevant compared with reward-relevant items from the evening to the morning test. These results suggest that a single night of CPAP use is not sufficient to improve
memory. Furthermore, while both groups became less confident in their responses from the evening to the morning test, the no-CPAP group showed a greater confidence decrease for reward-irrelevant compared with reward-relevant items. This suggests that
memory consolidation processes may have actually been more efficient for the no-CPAP group compared with the CPAP group, perhaps due to the difficulty adjusting to initial CPAP use. Overall, these results suggest that future research including objective sleep measures is necessary to fully understand the relationship between OSA, CPAP, and
memory consolidation.
Advisors/Committee Members: Westerberg, Carmen (advisor), Kelemen, William (committee member), Hu, Yueqin (committee member).
Subjects/Keywords: CPAP; OSA; Continuous Positive Airway Pressure; Obstructive Sleep Apnea; Memory; Memory consolidation; Declarative memory; Single use; Titration study; Consolidation
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Johnson, M. L. (2017). The Effect of Continuous Positive Airway Pressure (CPAP). (Masters Thesis). Texas State University – San Marcos. Retrieved from https://digital.library.txstate.edu/handle/10877/8768
Chicago Manual of Style (16th Edition):
Johnson, McKensey L. “The Effect of Continuous Positive Airway Pressure (CPAP).” 2017. Masters Thesis, Texas State University – San Marcos. Accessed March 07, 2021.
https://digital.library.txstate.edu/handle/10877/8768.
MLA Handbook (7th Edition):
Johnson, McKensey L. “The Effect of Continuous Positive Airway Pressure (CPAP).” 2017. Web. 07 Mar 2021.
Vancouver:
Johnson ML. The Effect of Continuous Positive Airway Pressure (CPAP). [Internet] [Masters thesis]. Texas State University – San Marcos; 2017. [cited 2021 Mar 07].
Available from: https://digital.library.txstate.edu/handle/10877/8768.
Council of Science Editors:
Johnson ML. The Effect of Continuous Positive Airway Pressure (CPAP). [Masters Thesis]. Texas State University – San Marcos; 2017. Available from: https://digital.library.txstate.edu/handle/10877/8768
University of New South Wales
21.
Tu, Sicong.
Memory consolidation in ageing and neurodegeneration.
Degree: Neuroscience Research Australia, 2012, University of New South Wales
URL: http://handle.unsw.edu.au/1959.4/52107
;
https://unsworks.unsw.edu.au/fapi/datastream/unsworks:10777/SOURCE01?view=true
► Research into the neuroanatomical bases of long-term memory has consistently implicated medial temporal lobe structures, namely the hippocampus, to play a critical role in the…
(more)
▼ Research into the neuroanatomical bases of long-term
memory has consistently implicated medial temporal lobe structures, namely the hippocampus, to play a critical role in the
consolidation of newly acquired episodic
memory (
memory of specific events in a persons life) for long-term storage. The work described in this thesis investigates
consolidation of anterograde episodic
memory using recognition and source (contextual) behavioural tasks with the addition of extensive neuroimaging techniques to better understand the role of medial temporal lobe structures when this process is intact and when it is impaired. We examined intact
consolidation and the cognitive effect of healthy ageing in a sample of young and elderly participants, and impaired
consolidation in early stage Alzheimers disease (AD) and semantic dementia (SD) patients, who show contrasting atrophy in the medial temporal lobe region. Building on previous studies, functional neuroimaging revealed the posterior region of the left hippocampus is crucial for intact long-term
consolidation of memories that have a contextual component. Diffusion tensor imaging further revealed greater white matter integrity in the fornix and cingulate, two subcortical structures responsible for efferent and afferent communication with the hippocampus, respectively, also predicted successful
consolidation. Behaviourally, cognitive changes associated with healthy ageing showed decreased recognition and source
memory retrieval after extended delays, but the same pattern of performance change over time was observed in young and elderly participants. In amnesic patients, AD showed a significant dissociation in the pattern of source
memory performance over time compared to controls while in SD this was only observed for recognition
memory. Considering atrophy in early stage AD is often reported to be confined to the hippocampus, these results are consistent with the multiple trace model of long-term
consolidation.The critical role of the hippocampus and adjacent subcortical structures along the Papez
memory circuit in long-term
consolidation of anterograde episodic
memory is consistent with our findings. In addition, our results from additional testing of a single SD patient found the
memory impairment appears to leave implicit long-term
memory retrieval intact. The theoretical and clinical implications of these findings for human long-term
memory will be discussed.
Advisors/Committee Members: Hornberger, Michael, Neuroscience Research Australia , Faculty of Medicine, UNSW, Piguet, Olivier, Neuroscience Research Australia , Faculty of Medicine, UNSW.
Subjects/Keywords: Ageing; Memory consolidation; Episodic memory; fMRI; Frontotemporal dementia
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Tu, S. (2012). Memory consolidation in ageing and neurodegeneration. (Masters Thesis). University of New South Wales. Retrieved from http://handle.unsw.edu.au/1959.4/52107 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:10777/SOURCE01?view=true
Chicago Manual of Style (16th Edition):
Tu, Sicong. “Memory consolidation in ageing and neurodegeneration.” 2012. Masters Thesis, University of New South Wales. Accessed March 07, 2021.
http://handle.unsw.edu.au/1959.4/52107 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:10777/SOURCE01?view=true.
MLA Handbook (7th Edition):
Tu, Sicong. “Memory consolidation in ageing and neurodegeneration.” 2012. Web. 07 Mar 2021.
Vancouver:
Tu S. Memory consolidation in ageing and neurodegeneration. [Internet] [Masters thesis]. University of New South Wales; 2012. [cited 2021 Mar 07].
Available from: http://handle.unsw.edu.au/1959.4/52107 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:10777/SOURCE01?view=true.
Council of Science Editors:
Tu S. Memory consolidation in ageing and neurodegeneration. [Masters Thesis]. University of New South Wales; 2012. Available from: http://handle.unsw.edu.au/1959.4/52107 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:10777/SOURCE01?view=true
22.
Rosier, Marius.
Émotions et sommeil paradoxal : étude comportementale, fonctionnelle et anatomique chez la souris : Emotions and paradoxical sleep : a behavioral, functional and anatomical study in mice.
Degree: Docteur es, Neurosciences, 2017, Lyon
URL: http://www.theses.fr/2017LYSE1016
► Le sommeil est un état de vigilance présent dans la plupart des espèces animales et impliqué dans de nombreuses fonctions. Le sommeil paradoxal (SP), un…
(more)
▼ Le sommeil est un état de vigilance présent dans la plupart des espèces animales et impliqué dans de nombreuses fonctions. Le sommeil paradoxal (SP), un des deux stades principaux de sommeil serait étroitement associé à la régulation des émotions. Cette régulation pourrait faciliter la consolidation de la mémoire émotionnelle, et paradoxalement diminuer le tonus émotionnel associé à cette mémoire. Nous proposons que l'hypothèse selon laquelle les premières heures de SP post-apprentissage soient importantes pour la consolidation à très long terme de la mémoire de peur. Pour cela, nous avons effectué un conditionnement de peur au contexte chez la souris suivi de 6h de privation spécifique de SP, et testé la mémoire récente (24 heures) et ancienne (30 jours) des animaux. Notre analyse du comportement révèle une altération spécifique des performances mnésiques des animaux privés de SP lors du rappel de la mémoire ancienne, pointant pour la première fois un rôle du SP post-apprentissage dans la consolidation à très long terme de la mémoire.Nous avons réalisé chez ces animaux une étude immunohistochimique visant à évaluer l'activité des populations neuronales de différentes aires corticales et sous-corticales lors du rappel. Pour cela, nous avons analysé l'expression du gène d'expression précoce zif268. Nos résultats révèlent une importance majeure du SP post-apprentissage dans la mise en place du processus de réorganisation systémique observé lors de la consolidation à très long terme.Nous avons ainsi montré que les premières heures de SP post-apprentissage peuvent être cruciales dans la régulation à très long terme d'une mémoire de la peur. Nous avons également montré que cette fonction du SP passerait par une initialisation précoce de la réorganisation à long terme des réseaux mnésiques, et notamment par une diminution homéostatique de l'activité dans les régions cérébrales impliquées dans l'expression des émotions
Sleep is a vigilance state observed in most of animal species and is involved in many functions. Paradoxical sleep (PS, or Rapid Eye Movement Sleep), an essential sleep state, seems to be closely linked to emotion regulation. It seems that one aspect of this function could be due to the potentiating role of PS in emotional long-term memory, and the paradoxical decrease in the emotional tone associated to the memorized event. We tested the hypothesis that the first hours of post-learning PS could be important for remote long term emotional memory in mice. We performed a contextual fear conditioning followed by 6 hours of PS deprivation, and assessed the memory at recent (24 hours) and remote (30 days) recall. Our behavioral analysis reveals a specific alteration of memory performances when animals were tested at remote delays, revealing for the first time a role of post-learning PS in remote memory consolidation.We then performed immunohistochemistry analysis of neuronal activation during memory recall by assessing the expression of the immediate early gene zif268 in a large number of areas involved in…
Advisors/Committee Members: Salin, Paul (thesis director).
Subjects/Keywords: Mémoire; Consolidation; Émotions; Sommeil paradoxal; Dépression; Memory; Consolidation; Emotions; Paradoxical sleep; Depression; 612.8
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Rosier, M. (2017). Émotions et sommeil paradoxal : étude comportementale, fonctionnelle et anatomique chez la souris : Emotions and paradoxical sleep : a behavioral, functional and anatomical study in mice. (Doctoral Dissertation). Lyon. Retrieved from http://www.theses.fr/2017LYSE1016
Chicago Manual of Style (16th Edition):
Rosier, Marius. “Émotions et sommeil paradoxal : étude comportementale, fonctionnelle et anatomique chez la souris : Emotions and paradoxical sleep : a behavioral, functional and anatomical study in mice.” 2017. Doctoral Dissertation, Lyon. Accessed March 07, 2021.
http://www.theses.fr/2017LYSE1016.
MLA Handbook (7th Edition):
Rosier, Marius. “Émotions et sommeil paradoxal : étude comportementale, fonctionnelle et anatomique chez la souris : Emotions and paradoxical sleep : a behavioral, functional and anatomical study in mice.” 2017. Web. 07 Mar 2021.
Vancouver:
Rosier M. Émotions et sommeil paradoxal : étude comportementale, fonctionnelle et anatomique chez la souris : Emotions and paradoxical sleep : a behavioral, functional and anatomical study in mice. [Internet] [Doctoral dissertation]. Lyon; 2017. [cited 2021 Mar 07].
Available from: http://www.theses.fr/2017LYSE1016.
Council of Science Editors:
Rosier M. Émotions et sommeil paradoxal : étude comportementale, fonctionnelle et anatomique chez la souris : Emotions and paradoxical sleep : a behavioral, functional and anatomical study in mice. [Doctoral Dissertation]. Lyon; 2017. Available from: http://www.theses.fr/2017LYSE1016
University of Toronto
23.
McKelvey, Kyra.
Event Typicality and Memory: Investigating How Prior Knowledge and Novelty Modulate Memory for Complex Events.
Degree: PhD, 2016, University of Toronto
URL: http://hdl.handle.net/1807/76560
► A complex set of processes and brain regions work together in healthy adults, allowing them to create and recall memories of daily events. Additionally, the…
(more)
▼ A complex set of processes and brain regions work together in healthy adults, allowing them to create and recall memories of daily events. Additionally, the perception and recall of these events is shaped by factors such as novelty and congruence with prior knowledge (typicality). Despite a long history of research, studies on the neural underpinnings of the mnemonic effects of novelty and typicality rarely examine complex naturalistic event memories. Moreover, it is uncertain how these effects evolve over time, as memories are stabilized and transformed from acquisition to retention and retrieval. In this thesis I use naturalistic film clip stimuli, behavioural measures, and functional magnetic resonance imaging (fMRI) to explore the effects of both novelty and typicality on the neural substrates mediating
memory, and examine how these effects evolve through encoding and retrieval over the course of a week. Behaviourally, I find that both typicality and novelty enhance
memory for events, but that atypical events are recalled with more errors over time. With respect to the neural bases of
memory, I demonstrate that the greatest differences based on event typicality are seen during encoding - when typicality is correlated with greater medial prefrontal cortex (mPFC) and parietal activation, while novelty is correlated with greater activation in the medial temporal lobes (MTLs) and posterior sensory cortices. During retrieval, however, such differences based on typicality are subtler, with retrieval supported by the MTLs, irrespective of event typicality, at all time points. Notwithstanding these overall neural similarities in the retrieval of all events, typical clips are associated with attenuated MTL activation during remote retrieval, indicating that recall dynamics may be influenced by event typicality over time. Furthermore, I provide evidence for differential functional connectivity of both the mPFC and MTLs during encoding and retrieval, based on event typicality. These results, which demonstrate how the neural substrates mediating narrative episodic memories are modulated by event typicality, are consistent with two complementary theories - Trace Transformation Theory and Schema Theory. Furthermore, they suggest, through mPFC and MTL functional connectivity, potential mechanisms by which typical and novel events may be differentially encoded and retrieved.
Advisors/Committee Members: Moscovitch, Morris, Psychology.
Subjects/Keywords: episodic memory; medial prefrontal cortex; medial temporal lobes; memory consolidation; schemas; semantic memory; 0623
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
McKelvey, K. (2016). Event Typicality and Memory: Investigating How Prior Knowledge and Novelty Modulate Memory for Complex Events. (Doctoral Dissertation). University of Toronto. Retrieved from http://hdl.handle.net/1807/76560
Chicago Manual of Style (16th Edition):
McKelvey, Kyra. “Event Typicality and Memory: Investigating How Prior Knowledge and Novelty Modulate Memory for Complex Events.” 2016. Doctoral Dissertation, University of Toronto. Accessed March 07, 2021.
http://hdl.handle.net/1807/76560.
MLA Handbook (7th Edition):
McKelvey, Kyra. “Event Typicality and Memory: Investigating How Prior Knowledge and Novelty Modulate Memory for Complex Events.” 2016. Web. 07 Mar 2021.
Vancouver:
McKelvey K. Event Typicality and Memory: Investigating How Prior Knowledge and Novelty Modulate Memory for Complex Events. [Internet] [Doctoral dissertation]. University of Toronto; 2016. [cited 2021 Mar 07].
Available from: http://hdl.handle.net/1807/76560.
Council of Science Editors:
McKelvey K. Event Typicality and Memory: Investigating How Prior Knowledge and Novelty Modulate Memory for Complex Events. [Doctoral Dissertation]. University of Toronto; 2016. Available from: http://hdl.handle.net/1807/76560
University of Lethbridge
24.
University of Lethbridge. Faculty of Arts and Science.
Low acetylcholine during early sleep is crucial for motor memory consolidation
.
Degree: 2018, University of Lethbridge
URL: http://hdl.handle.net/10133/5108
► I investigated a potential relationship between motor memory and acetylcholine activity during early sleep characterized by slow-wave electroencephalographic activity and reduced cholinergic tone. I tested…
(more)
▼ I investigated a potential relationship between motor memory and acetylcholine activity during early sleep characterized by slow-wave electroencephalographic activity and reduced cholinergic tone. I tested the hypothesis that altering acetylcholine levels during early sleep would disrupt motor memory consolidation. I trained 93 wild-type and 17 transgenic adult mice on motor tasks either rotarod or skilled-forelimb reach. Immediately after training, I either increased or decreased acetylcholine levels in the subsequent post-learning early sleep. Upon retesting performance on motor tasks, I discovered that increasing acetylcholine levels impaired motor memory consolidation while decreasing acetylcholine levels did not have an effect. I also found a larger involvement of muscarinic acetylcholine receptors compared to nicotinic ones for motor memory consolidation. With filming and electrophysiology, I determined that increasing acetylcholine altered sleep structure and reduced slow-wave activity in early sleep. These results suggest that motor memories are consolidated during slow-wave sleep when cholinergic levels are low.
Subjects/Keywords: motor memory consolidation;
sleep;
acetylcholine neuromodulation;
skilled forelimb reach task;
rotarod task;
electrophysiology;
Acetylcholine;
Memory consolidation;
Slow wave sleep
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Science, U. o. L. F. o. A. a. (2018). Low acetylcholine during early sleep is crucial for motor memory consolidation
. (Thesis). University of Lethbridge. Retrieved from http://hdl.handle.net/10133/5108
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Science, University of Lethbridge. Faculty of Arts and. “Low acetylcholine during early sleep is crucial for motor memory consolidation
.” 2018. Thesis, University of Lethbridge. Accessed March 07, 2021.
http://hdl.handle.net/10133/5108.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Science, University of Lethbridge. Faculty of Arts and. “Low acetylcholine during early sleep is crucial for motor memory consolidation
.” 2018. Web. 07 Mar 2021.
Vancouver:
Science UoLFoAa. Low acetylcholine during early sleep is crucial for motor memory consolidation
. [Internet] [Thesis]. University of Lethbridge; 2018. [cited 2021 Mar 07].
Available from: http://hdl.handle.net/10133/5108.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Science UoLFoAa. Low acetylcholine during early sleep is crucial for motor memory consolidation
. [Thesis]. University of Lethbridge; 2018. Available from: http://hdl.handle.net/10133/5108
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
University of California – Riverside
25.
McDevitt, Elizabeth Ann.
The Memory Function of REM Sleep.
Degree: Psychology, 2017, University of California – Riverside
URL: http://www.escholarship.org/uc/item/3dh0p3w9
► How does the human brain adapt to changes in the environment and store information to form memories? Decades of research has explored how information input…
(more)
▼ How does the human brain adapt to changes in the environment and store information to form memories? Decades of research has explored how information input from the environment triggers plastic changes in the brain, leading to new memory traces that have the potential to become long-term memories. My thesis asks what the optimal brain states (i.e., level of engagement with the external environment and the internal neural dynamics) are for these memory consolidation processes to occur. Sleep promotes memory consolidation (Rasch & Born, 2013), with the majority of prior studies focusing on the role of non-rapid eye movement (NREM) sleep for reducing forgetting in explicit memory contexts. Less is known about the role of rapid eye movement (REM) sleep, however, studies have shown REM may be critical for implicit or procedural learning (Cai, Mednick, Harrison, Kanady, & Mednick, 2009; Mednick, Nakayama, & Stickgold, 2003; Plihal & Born, 1997). The current thesis examines the effect of different brain states on memory consolidation, with a specific focus on visual perceptual learning. In the first two studies, I manipulated levels of sensory input from the external environment by using different wake conditions (active and quiet wake) compared with sleep, and manipulated internal neural dynamics by using different sleep conditions (naps with NREM sleep alone or NREM plus REM sleep). I tested perceptual learning of both motion direction (Study 1) and texture (Study 2) discrimination. My results show that REM sleep promotes training-induced improvements in performance (i.e., plasticity) on visual skills tasks. I hypothesize that REM sleep is the optimal brain state for this consolidation due to its unique combination of low external input coupled with neural dynamics that promote plasticity. As a secondary aim of this thesis, I explored the utility of napping beyond its use as an experimental tool by examining individual differences in nap-dependent learning. In other words, should everyone nap to boost daytime performance? I found that learning profiles after a nap are different in men and women (Study 1), and that people who regularly nap show greater magnitude of nap-dependent learning compared to people who nap infrequently (Study 3). These findings should be taken into consideration when recommending napping in operational settings.
Subjects/Keywords: Cognitive psychology; interference; memory consolidation; napping; REM sleep; sex differences; sleep
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
McDevitt, E. A. (2017). The Memory Function of REM Sleep. (Thesis). University of California – Riverside. Retrieved from http://www.escholarship.org/uc/item/3dh0p3w9
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
McDevitt, Elizabeth Ann. “The Memory Function of REM Sleep.” 2017. Thesis, University of California – Riverside. Accessed March 07, 2021.
http://www.escholarship.org/uc/item/3dh0p3w9.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
McDevitt, Elizabeth Ann. “The Memory Function of REM Sleep.” 2017. Web. 07 Mar 2021.
Vancouver:
McDevitt EA. The Memory Function of REM Sleep. [Internet] [Thesis]. University of California – Riverside; 2017. [cited 2021 Mar 07].
Available from: http://www.escholarship.org/uc/item/3dh0p3w9.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
McDevitt EA. The Memory Function of REM Sleep. [Thesis]. University of California – Riverside; 2017. Available from: http://www.escholarship.org/uc/item/3dh0p3w9
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
26.
Shepley, Avril.
Accelerated forgetting and memory consolidation in children with idiopathic generalised epilepsy.
Degree: 2011, University of Edinburgh
URL: http://hdl.handle.net/1842/6037
► Long-term memory retention and learning of verbal and non-verbal material was investigated in children with idiopathic generalised epilepsy (IGE) and healthy controls. Ten children with…
(more)
▼ Long-term
memory retention and learning of verbal and non-verbal material was investigated in children with idiopathic generalised epilepsy (IGE) and healthy controls. Ten children with IGE were compared to 12 control children for their initial learning ability and
memory retention of verbal and non-verbal material at delays of 30-minutes and 1-week. A minimum learning criterion was used to control for initial learning. No significant group differences were found for the initial learning and recall of non-verbal material across delays. In the verbal test children with IGE did not differ significantly from controls in the number of learning trials they required to achieve criterion or in their recall at the 30-minute delay, however one week later they recalled significantly less than controls. There were no significant group differences for the recognition of verbal material across delays. These findings suggest that children with IGE have difficulty retrieving verbal material that has been successfully encoded and stored in long-term
memory.
Advisors/Committee Members: Abrahams, Sharon, MacPherson, Sarah.
Subjects/Keywords: Accelerated forgetting; memory consolidation
…2000). As such
the process of memory consolidation could take days, weeks, months or… …memory consolidation has
been of interest to researchers for over a century the exact time… …course and mechanisms of
memory consolidation remain unclear (Meeter & Murre, 2004)… …in the initial stages of memory
consolidation (Mayes et al.. 2003).
Squire and… …mechanisms of memory consolidation, it
seems apparent that interactions between the MTL and…
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Shepley, A. (2011). Accelerated forgetting and memory consolidation in children with idiopathic generalised epilepsy. (Thesis). University of Edinburgh. Retrieved from http://hdl.handle.net/1842/6037
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Shepley, Avril. “Accelerated forgetting and memory consolidation in children with idiopathic generalised epilepsy.” 2011. Thesis, University of Edinburgh. Accessed March 07, 2021.
http://hdl.handle.net/1842/6037.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Shepley, Avril. “Accelerated forgetting and memory consolidation in children with idiopathic generalised epilepsy.” 2011. Web. 07 Mar 2021.
Vancouver:
Shepley A. Accelerated forgetting and memory consolidation in children with idiopathic generalised epilepsy. [Internet] [Thesis]. University of Edinburgh; 2011. [cited 2021 Mar 07].
Available from: http://hdl.handle.net/1842/6037.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Shepley A. Accelerated forgetting and memory consolidation in children with idiopathic generalised epilepsy. [Thesis]. University of Edinburgh; 2011. Available from: http://hdl.handle.net/1842/6037
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Brigham Young University
27.
James, Jesse Ray.
The Effect of Sleep-Dependent Consolidation on Pattern Separation and Pattern Completion in Delayed Retrieval.
Degree: PhD, 2014, Brigham Young University
URL: https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=5376&context=etd
► While people sleep, the brain replays the same neural firings that resulted from waking activities that day. This results in greater memory strength following…
(more)
▼ While people sleep, the brain replays the same neural firings that resulted from waking activities that day. This results in greater memory strength following a sleeping delay than a waking delay. The current project built upon this fact in a series of three experiments. Experiment 1. Although previous research has demonstrated a benefit of sleep to memory strength, the literature has not established the impact of sleep on memory specificity. Computational models of medial temporal lobe function posit that discrimination and generalization across similar memories are accomplished through processes known as pattern separation and pattern completion, respectively. To discover whether sleep predisposes people toward pattern separation or pattern completion, participants studied pictures of common objects. After a 12-hour delay, during which participants either slept or stayed awake, participants indicated whether “lure” images were exactly the same or merely similar to those they studied. There was better memory discrimination in those who slept, consistent with a bias toward pattern separation following sleep. Experiment 2. In order to discover whether the pattern of memory demonstrated in Experiment 1 would carry over to semantic memories, participants studied textbook material and took a true/false test 12 hours later. There was a shift in the response trends following sleep, such that participants were more likely to mistakenly endorse highly similar false statements as “true” but were also more likely to correctly endorse more dissimilar false statements as “false.” However, we did not detect evidence of an increased bias toward pattern separation or pattern completion following sleep for this material. Our findings appear consistent with the prediction that memory specificity is benefitted by sleep. Experiment 3. Previous research has demonstrated that memories encoded later in the day are consolidated better than memories encoded earlier in the day. However, these studies have not controlled for the differential decay that memories suffer across these two elapsed periods. In this study, we attempted to show the degree of improvement afforded by sleep using a before-sleep comparison group. However, post hoc analyses revealed a significant interaction between the proposed outcomes and whether participants had napped during the day. These preliminary findings may suggest that napping differentially affects the consolidation of information studied before and after napping.
Subjects/Keywords: memory; sleep; consolidation; pattern separation; pattern completion; Psychology
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
James, J. R. (2014). The Effect of Sleep-Dependent Consolidation on Pattern Separation and Pattern Completion in Delayed Retrieval. (Doctoral Dissertation). Brigham Young University. Retrieved from https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=5376&context=etd
Chicago Manual of Style (16th Edition):
James, Jesse Ray. “The Effect of Sleep-Dependent Consolidation on Pattern Separation and Pattern Completion in Delayed Retrieval.” 2014. Doctoral Dissertation, Brigham Young University. Accessed March 07, 2021.
https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=5376&context=etd.
MLA Handbook (7th Edition):
James, Jesse Ray. “The Effect of Sleep-Dependent Consolidation on Pattern Separation and Pattern Completion in Delayed Retrieval.” 2014. Web. 07 Mar 2021.
Vancouver:
James JR. The Effect of Sleep-Dependent Consolidation on Pattern Separation and Pattern Completion in Delayed Retrieval. [Internet] [Doctoral dissertation]. Brigham Young University; 2014. [cited 2021 Mar 07].
Available from: https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=5376&context=etd.
Council of Science Editors:
James JR. The Effect of Sleep-Dependent Consolidation on Pattern Separation and Pattern Completion in Delayed Retrieval. [Doctoral Dissertation]. Brigham Young University; 2014. Available from: https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=5376&context=etd
University of Arizona
28.
Harper, Blaine.
Mechanisms of Sleep-Dependent Memory Consolidation in the Rodent Prefrontal Cortex
.
Degree: 2020, University of Arizona
URL: http://hdl.handle.net/10150/642135
► Animals learn over the course of a lifetime, and the ability to retrieve memories after long delays depends on memory consolidation. This process involves coordinated…
(more)
▼ Animals learn over the course of a lifetime, and the ability to retrieve memories after long delays depends on
memory consolidation. This process involves coordinated oscillatory and cellular activity in the cortex and hippocampus during sleep, but it is not clear how sleep activity after learning engages this mechanism. Studies of
memory consolidation in rats have identified two types of oscillatory activity—sleep spindles in the prefrontal cortex and sharp wave-ripples in the hippocampus—as events that may guide cell activity that supports
memory consolidation.
This dissertation comprises studies of electrophysiological methods and behavioral paradigms used in the investigation of
memory consolidation, and applies these to experimental work on oscillations and cell activity occurring during sleep. The methodological study develops a procedure for the selection of spindle detection parameters and extends it for application to experimental work. The study of behavioral tasks relevant to
memory consolidation examines two existing tasks—one driven by cues, and the other designed to require new learning—and identifies differences in their behavioral profiles, but not their impact on broad sleep features, establishing that they constitute a well-matched pair of tasks for reasoning about the differential recruitment of
memory consolidation mechanisms.
In experimental work regarding the influence of these tasks on spindles and ripples, coordination is observed to occur between these two oscillations but no effect is found for either task on the oscillation density of ripples (per second) or spindles (per minute), or on the
coordination between them. Further investigation of the coordination of cell activity during spindles shows that prefrontal cell activity may be influenced by co-occurring ripple activity, yet this influence does not vary with respect to task exposures. The possibility is discussed that the lack of task effects is due to higher task familiarity than in other
memory consolidation research.
Advisors/Committee Members: Ryan, Lee (advisor), Edgin, Jamie O. (committeemember), Fernandez, Fabian (committeemember), Ruiz, John (committeemember), Nadel, Lynn (committeemember).
Subjects/Keywords: algorithm performance;
electrophysiology;
memory consolidation;
neuroscience;
oscillation;
psychology
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Harper, B. (2020). Mechanisms of Sleep-Dependent Memory Consolidation in the Rodent Prefrontal Cortex
. (Doctoral Dissertation). University of Arizona. Retrieved from http://hdl.handle.net/10150/642135
Chicago Manual of Style (16th Edition):
Harper, Blaine. “Mechanisms of Sleep-Dependent Memory Consolidation in the Rodent Prefrontal Cortex
.” 2020. Doctoral Dissertation, University of Arizona. Accessed March 07, 2021.
http://hdl.handle.net/10150/642135.
MLA Handbook (7th Edition):
Harper, Blaine. “Mechanisms of Sleep-Dependent Memory Consolidation in the Rodent Prefrontal Cortex
.” 2020. Web. 07 Mar 2021.
Vancouver:
Harper B. Mechanisms of Sleep-Dependent Memory Consolidation in the Rodent Prefrontal Cortex
. [Internet] [Doctoral dissertation]. University of Arizona; 2020. [cited 2021 Mar 07].
Available from: http://hdl.handle.net/10150/642135.
Council of Science Editors:
Harper B. Mechanisms of Sleep-Dependent Memory Consolidation in the Rodent Prefrontal Cortex
. [Doctoral Dissertation]. University of Arizona; 2020. Available from: http://hdl.handle.net/10150/642135
University of Cambridge
29.
Vousden, George Henry.
An assessment of reconsolidation blockade to disrupt memories relevant to psychiatric disorders.
Degree: PhD, 2017, University of Cambridge
URL: https://www.repository.cam.ac.uk/handle/1810/267292
► Consolidated memories can become reactivated in order to permit the integration of new information into the memory trace. Blockade of the resultant process, reconsolidation, with…
(more)
▼ Consolidated memories can become reactivated in order to permit the integration of new information into the memory trace. Blockade of the resultant process, reconsolidation, with NMDA receptor antagonists or protein synthesis inhibition can lead to a decrease in subsequent memory expression. This may offer a potential tool for the treatment of psychiatric disorders characterised by maladaptive memories, including drug addiction and post-traumatic disorder.
Given the importance of instrumental associations in supporting drug addiction experiments in Chapters 3 & 4 aimed to disrupt reconsolidation of these memories. Treatment with an NMDA receptor antagonist prior to retrieval sessions of various durations was not able to consistently prevent reconsolidation of these associations.
Drug addiction is characterised by memories that have been formed not over days or weeks, but months or years. Experiments in Chapters 5 & 6 therefore investigated how the extent of training affects the propensity of an appetitive pavlovian memory to reconsolidate. Experiments in Chapter 5 were not able disrupt reconsolidation of these memories after a relatively short period of training. In Chapter 6 attempts to disrupt reconsolidation of a cocaine-seeking memory having undergone extensive training (>1 month, designed to promote the formation of drug-seeking habits) were also unsuccessful. However, when animals were trained in a similar fashion to respond for a food reinforcer treatment with a NMDA receptor antagonist prior to a reactivation session resulted in a decrease in food-seeking behaviour the following day. However, this deficit was only found in the first test session; drug treatment had no effect on responding following reminder of the memory.
If data from preclinical studies are to inform future psychiatric treatments the findings from these works must be robust and replicable. Experiments in previous chapters encountered several issues in this regard, namely the repeated inability to prevent reconsolidation with NMDA receptor antagonism. Given that reconsolidation of auditory fear memories is well characterised a final series of experiments in Chapter 7 used this procedure to explore the possible reasons for the fleeting or absent effects of disrupted memory reconsolidation in previous chapters. Despite the use of similar methods as published reports showing decreases in memory expression as a result of blockade of reconsolidation it was not possible to disrupt this process with NMDA receptor antagonism or protein synthesis inhibition. Results suggested that the failure to observe reactivation-dependent amnesia was due to the amnestic agent used not being able to prevent reconsolidation, should it be taking place, and a failure of the given retrieval trial to result in memory reactivation.
On numerous occasions throughout this thesis it was not possible to disrupt memory reconsolidation. One difficulty in interpreting null data of this nature is that it is often unclear whether the results are due to insufficient…
Subjects/Keywords: reconsolidation; memory; addiction; consolidation; nmda; ptsd; post-traumatic stress disorder; instrumental
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Vousden, G. H. (2017). An assessment of reconsolidation blockade to disrupt memories relevant to psychiatric disorders. (Doctoral Dissertation). University of Cambridge. Retrieved from https://www.repository.cam.ac.uk/handle/1810/267292
Chicago Manual of Style (16th Edition):
Vousden, George Henry. “An assessment of reconsolidation blockade to disrupt memories relevant to psychiatric disorders.” 2017. Doctoral Dissertation, University of Cambridge. Accessed March 07, 2021.
https://www.repository.cam.ac.uk/handle/1810/267292.
MLA Handbook (7th Edition):
Vousden, George Henry. “An assessment of reconsolidation blockade to disrupt memories relevant to psychiatric disorders.” 2017. Web. 07 Mar 2021.
Vancouver:
Vousden GH. An assessment of reconsolidation blockade to disrupt memories relevant to psychiatric disorders. [Internet] [Doctoral dissertation]. University of Cambridge; 2017. [cited 2021 Mar 07].
Available from: https://www.repository.cam.ac.uk/handle/1810/267292.
Council of Science Editors:
Vousden GH. An assessment of reconsolidation blockade to disrupt memories relevant to psychiatric disorders. [Doctoral Dissertation]. University of Cambridge; 2017. Available from: https://www.repository.cam.ac.uk/handle/1810/267292
Boston University
30.
Kinsky, Nathaniel Reid.
Long-term stability of the hippocampal neural code as a substrate for episodic memory.
Degree: PhD, Neuroscience, 2019, Boston University
URL: http://hdl.handle.net/2144/36639
► The hippocampus supports the initial formation and recall of episodic memories, as well as the consolidation of short-term into long-term memories. The ability of hippocampal…
(more)
▼ The hippocampus supports the initial formation and recall of episodic memories, as well as the
consolidation of short-term into long-term memories. The ability of hippocampal neurons to rapidly change their connection strengths during learning and maintain these changes over long time-scales may provide a mechanism supporting
memory. However, little evidence currently exists concerning the long-term stability of information contained in hippocampal neuronal activity, likely due to limitations in recording extracellular activity in vivo from the same neurons across days. In this thesis I employ calcium imaging in freely moving mice to longitudinally track the activity of large ensembles of hippocampal neurons. Using this technology, I explore the proposal that long-term stability of hippocampal information provides a substrate for episodic
memory in three different ways.
First, I tested the hypothesis that hippocampal activity should remain stable across days in the absence of learning. I found that place cells – hippocampal neurons containing information about a mouse’s position – maintain a coherent map relative to each other across long time-scales but exhibit instability in how they anchor to the external world. Furthermore, I found that coherent maps were frequently used to represent a different environment and incorporated learning via changes in a subset of neurons. Next, I examined how learning a spatial alternation task impacts neuron stability. I found that splitter neurons whose activity patterns reflected an animal’s future or past trajectory emerged relatively slowly when compared to place cells. However, splitter neurons remained more consistently active and relayed more consistent spatial information across days than did place cells, suggesting that the utility of information provided by a neuron influences its long term stability. Last, I investigated how protein synthesis, known to be necessary for long-term maintenance of changes in hippocampal neuron connection strengths and for proper
memory consolidation, influences their activity patterns across days. I found that along with blocking
memory consolidation, inhibiting protein synthesis induced a profound, long-lasting decrease in neuronal activity up to two days later. These results combined demonstrate the importance of rapid, lasting changes in the hippocampal neuronal code to supporting long-term
memory.
Advisors/Committee Members: Hasselmo, Michael E. (advisor).
Subjects/Keywords: Neurosciences; Calcium imaging; Hippocampus; Memory consolidation; Protein synthesis; Remapping; Stability
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Kinsky, N. R. (2019). Long-term stability of the hippocampal neural code as a substrate for episodic memory. (Doctoral Dissertation). Boston University. Retrieved from http://hdl.handle.net/2144/36639
Chicago Manual of Style (16th Edition):
Kinsky, Nathaniel Reid. “Long-term stability of the hippocampal neural code as a substrate for episodic memory.” 2019. Doctoral Dissertation, Boston University. Accessed March 07, 2021.
http://hdl.handle.net/2144/36639.
MLA Handbook (7th Edition):
Kinsky, Nathaniel Reid. “Long-term stability of the hippocampal neural code as a substrate for episodic memory.” 2019. Web. 07 Mar 2021.
Vancouver:
Kinsky NR. Long-term stability of the hippocampal neural code as a substrate for episodic memory. [Internet] [Doctoral dissertation]. Boston University; 2019. [cited 2021 Mar 07].
Available from: http://hdl.handle.net/2144/36639.
Council of Science Editors:
Kinsky NR. Long-term stability of the hippocampal neural code as a substrate for episodic memory. [Doctoral Dissertation]. Boston University; 2019. Available from: http://hdl.handle.net/2144/36639
◁ [1] [2] [3] [4] [5] ▶
. 
Open Access Theses and Dissertations
