subject:(medical device)

Delft University of Technology

1. Dinh, P.L. Olla-Deluxe, development of a patient-specific commode:.

Degree: 2015, Delft University of Technology

URL: http://resolver.tudelft.nl/uuid:5147ce96-4d99-4642-8d78-9b013ba0baa2

► The new concept introduces a patient-specific commode, achieved by connecting the commode to the hospital bed. This will diminish the chances of cross-contamination between patients.… (more)

Subjects/Keywords: commode; medical device

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APA (6^th Edition):

Dinh, P. L. (2015). Olla-Deluxe, development of a patient-specific commode:. (Masters Thesis). Delft University of Technology. Retrieved from http://resolver.tudelft.nl/uuid:5147ce96-4d99-4642-8d78-9b013ba0baa2

Chicago Manual of Style (16^th Edition):

Dinh, P L. “Olla-Deluxe, development of a patient-specific commode:.” 2015. Masters Thesis, Delft University of Technology. Accessed December 13, 2019. http://resolver.tudelft.nl/uuid:5147ce96-4d99-4642-8d78-9b013ba0baa2.

MLA Handbook (7^th Edition):

Dinh, P L. “Olla-Deluxe, development of a patient-specific commode:.” 2015. Web. 13 Dec 2019.

Vancouver:

Dinh PL. Olla-Deluxe, development of a patient-specific commode:. [Internet] [Masters thesis]. Delft University of Technology; 2015. [cited 2019 Dec 13]. Available from: http://resolver.tudelft.nl/uuid:5147ce96-4d99-4642-8d78-9b013ba0baa2.

Council of Science Editors:

Dinh PL. Olla-Deluxe, development of a patient-specific commode:. [Masters Thesis]. Delft University of Technology; 2015. Available from: http://resolver.tudelft.nl/uuid:5147ce96-4d99-4642-8d78-9b013ba0baa2

Victoria University of Wellington

2. Houlihan, Christina. The development of an intellectual property strategy for a biotechnology company.

Degree: 2015, Victoria University of Wellington

URL: http://hdl.handle.net/10063/4890

► The 2014 Masters of Advanced Technology Enterprise (MATE) programme is a multi-disciplinary course with the goal of creating teams that explore the challenges of creating… (more)

Subjects/Keywords: Patent; Biotechnology; Strategy; Medical Device

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Houlihan, C. (2015). The development of an intellectual property strategy for a biotechnology company. (Masters Thesis). Victoria University of Wellington. Retrieved from http://hdl.handle.net/10063/4890

Chicago Manual of Style (16^th Edition):

Houlihan, Christina. “The development of an intellectual property strategy for a biotechnology company.” 2015. Masters Thesis, Victoria University of Wellington. Accessed December 13, 2019. http://hdl.handle.net/10063/4890.

MLA Handbook (7^th Edition):

Houlihan, Christina. “The development of an intellectual property strategy for a biotechnology company.” 2015. Web. 13 Dec 2019.

Vancouver:

Houlihan C. The development of an intellectual property strategy for a biotechnology company. [Internet] [Masters thesis]. Victoria University of Wellington; 2015. [cited 2019 Dec 13]. Available from: http://hdl.handle.net/10063/4890.

Council of Science Editors:

Houlihan C. The development of an intellectual property strategy for a biotechnology company. [Masters Thesis]. Victoria University of Wellington; 2015. Available from: http://hdl.handle.net/10063/4890

University of Manchester

3. Forbes, Sarah. Assessment of Apolipoprotein E Derived Peptides as Novel Antimicrobials for the Coating of Biomedical Devices.

Degree: 2013, University of Manchester

URL: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:185610

► The microbial contamination of biomedical devices is a leading cause of hospital- acquired infection. A number of strategies aimed at developing device coatings that are… (more)

▼ The microbial contamination of biomedical devices is a leading cause of hospital- acquired infection. A number of strategies aimed at developing device coatings that are refractory to microbial adhesion, colonisation and biofilm formation have been developed, but the problem remains. The incorporation of biocides into biomedical device surface coatings has shown promising results in preventing the establishment of infection. Current controversy over the possibility that extensive use of biocides could potentially lead to antimicrobial resistance has fuelled the search for new actives with good antimicrobial activity and low cytotoxicity, that maintain marked efficacy after prolonged use. This doctoral thesis aims to evaluate the antimicrobial potential of a novel peptide based on human apolipoprotein E receptor binding region (apoEdpL-W). The spectrum of antimicrobial activity and anti-biofilm efficacy of apoEdpL-W was compared to that of common biocides polyhexamethylene biguanide, triclosan, cetrimide and chlorhexidine. The potential to induce bacterial insusceptibility towards these agents after long-term sub-lethal level exposure was assessed. Initial examination against 18 test microorganisms, commonly associated with device infection, showed that apoEdpL-W displayed broad-range antimicrobial and anti-biofilm efficacy. ApoEdpL-W also maintained marked antibacterial activity after incorporation onto various biomaterial polymers, often used in device surface coatings. Alterations in bacterial susceptibility after prolonged exposure to apoEdpL-W, as well as to the other biocides, were often temporary and partially reverted once the bacteria had been grown in the absence of the antimicrobial agent. The adaption of Staphylococcus aureus to the presence of triclosan resulted in the formation of small colony variants (SVCs) with reduced triclosan susceptibility. Analysis of the physiological characteristics of the triclosan induced SCVs revealed the loss of virulence determinants and potentially reduced pathogenic capability, when compared to the parent strain. The biocompatibility index values of the test actives were determined by the parallel assessment of their antibacterial activity and in vitro cytotoxicity. ApoEdpL-W showed good antibacterial efficacy whilst remaining relatively less toxic to mammalian cells than triclosan or chlorhexidine. We studied the interactions of the test antimicrobials with a preformed phospholipid bilayer using the quartz crystal microbalance device and dual polarisation interferometry, to better understand potential mode of action. Analysis revealed that ApoEdpL-W and PHMB induced the highest level of bilayer disruption, of all the antimicrobials tested. These data suggest that apoEdpL-W demonstrates antibacterial activity; biocompatibility and long-term efficacy on a level that compares favourably to that of currently used biocides. The peptide demonstrates good antimicrobial efficacy when incorporated into a range of biomaterial polymers and shows the potential to be developed as an… Advisors/Committee Members: MCBAIN, ANDREW AJ, Dobson, Curtis, Mcbain, Andrew.

Subjects/Keywords: Biocide; Antimicrobial peptide; Medical device

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Forbes, S. (2013). Assessment of Apolipoprotein E Derived Peptides as Novel Antimicrobials for the Coating of Biomedical Devices. (Doctoral Dissertation). University of Manchester. Retrieved from http://www.manchester.ac.uk/escholar/uk-ac-man-scw:185610

Chicago Manual of Style (16^th Edition):

Forbes, Sarah. “Assessment of Apolipoprotein E Derived Peptides as Novel Antimicrobials for the Coating of Biomedical Devices.” 2013. Doctoral Dissertation, University of Manchester. Accessed December 13, 2019. http://www.manchester.ac.uk/escholar/uk-ac-man-scw:185610.

MLA Handbook (7^th Edition):

Forbes, Sarah. “Assessment of Apolipoprotein E Derived Peptides as Novel Antimicrobials for the Coating of Biomedical Devices.” 2013. Web. 13 Dec 2019.

Vancouver:

Forbes S. Assessment of Apolipoprotein E Derived Peptides as Novel Antimicrobials for the Coating of Biomedical Devices. [Internet] [Doctoral dissertation]. University of Manchester; 2013. [cited 2019 Dec 13]. Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:185610.

Council of Science Editors:

Forbes S. Assessment of Apolipoprotein E Derived Peptides as Novel Antimicrobials for the Coating of Biomedical Devices. [Doctoral Dissertation]. University of Manchester; 2013. Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:185610

University of Manchester

4. Forbes, Sarah. Assessment of apolipoprotein E derived peptides as novel antimicrobials for the coating of biomedical devices.

Degree: PhD, 2013, University of Manchester

URL: https://www.research.manchester.ac.uk/portal/en/theses/assessment-of-apolipoprotein-e-derived-peptides-as-novel-antimicrobials-for-the-coating-of-biomedical-devices(86d1dcbb-33f8-4ea4-bec0-9f07b97c29b6).html ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.734200

► The microbial contamination of biomedical devices is a leading cause of hospital- acquired infection. A number of strategies aimed at developing device coatings that are… (more)

▼ The microbial contamination of biomedical devices is a leading cause of hospital- acquired infection. A number of strategies aimed at developing device coatings that are refractory to microbial adhesion, colonisation and biofilm formation have been developed, but the problem remains. The incorporation of biocides into biomedical device surface coatings has shown promising results in preventing the establishment of infection. Current controversy over the possibility that extensive use of biocides could potentially lead to antimicrobial resistance has fuelled the search for new actives with good antimicrobial activity and low cytotoxicity, that maintain marked efficacy after prolonged use. This doctoral thesis aims to evaluate the antimicrobial potential of a novel peptide based on human apolipoprotein E receptor binding region (apoEdpL-W). The spectrum of antimicrobial activity and anti-biofilm efficacy of apoEdpL-W was compared to that of common biocides polyhexamethylene biguanide, triclosan, cetrimide and chlorhexidine. The potential to induce bacterial insusceptibility towards these agents after long-term sub-lethal level exposure was assessed. Initial examination against 18 test microorganisms, commonly associated with device infection, showed that apoEdpL-W displayed broad-range antimicrobial and anti-biofilm efficacy. ApoEdpL-W also maintained marked antibacterial activity after incorporation onto various biomaterial polymers, often used in device surface coatings. Alterations in bacterial susceptibility after prolonged exposure to apoEdpL-W, as well as to the other biocides, were often temporary and partially reverted once the bacteria had been grown in the absence of the antimicrobial agent. The adaption of Staphylococcus aureus to the presence of triclosan resulted in the formation of small colony variants (SVCs) with reduced triclosan susceptibility. Analysis of the physiological characteristics of the triclosan induced SCVs revealed the loss of virulence determinants and potentially reduced pathogenic capability, when compared to the parent strain. The biocompatibility index values of the test actives were determined by the parallel assessment of their antibacterial activity and in vitro cytotoxicity. ApoEdpL-W showed good antibacterial efficacy whilst remaining relatively less toxic to mammalian cells than triclosan or chlorhexidine. We studied the interactions of the test antimicrobials with a preformed phospholipid bilayer using the quartz crystal microbalance device and dual polarisation interferometry, to better understand potential mode of action. Analysis revealed that ApoEdpL-W and PHMB induced the highest level of bilayer disruption, of all the antimicrobials tested. These data suggest that apoEdpL-W demonstrates antibacterial activity; biocompatibility and long-term efficacy on a level that compares favourably to that of currently used biocides. The peptide demonstrates good antimicrobial efficacy when incorporated into a range of biomaterial polymers and shows the potential to be developed as an…

Subjects/Keywords: Medical device; Biocide; Antimicrobial peptide

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Forbes, S. (2013). Assessment of apolipoprotein E derived peptides as novel antimicrobials for the coating of biomedical devices. (Doctoral Dissertation). University of Manchester. Retrieved from https://www.research.manchester.ac.uk/portal/en/theses/assessment-of-apolipoprotein-e-derived-peptides-as-novel-antimicrobials-for-the-coating-of-biomedical-devices(86d1dcbb-33f8-4ea4-bec0-9f07b97c29b6).html ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.734200

Chicago Manual of Style (16^th Edition):

Forbes, Sarah. “Assessment of apolipoprotein E derived peptides as novel antimicrobials for the coating of biomedical devices.” 2013. Doctoral Dissertation, University of Manchester. Accessed December 13, 2019. https://www.research.manchester.ac.uk/portal/en/theses/assessment-of-apolipoprotein-e-derived-peptides-as-novel-antimicrobials-for-the-coating-of-biomedical-devices(86d1dcbb-33f8-4ea4-bec0-9f07b97c29b6).html ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.734200.

MLA Handbook (7^th Edition):

Forbes, Sarah. “Assessment of apolipoprotein E derived peptides as novel antimicrobials for the coating of biomedical devices.” 2013. Web. 13 Dec 2019.

Vancouver:

Forbes S. Assessment of apolipoprotein E derived peptides as novel antimicrobials for the coating of biomedical devices. [Internet] [Doctoral dissertation]. University of Manchester; 2013. [cited 2019 Dec 13]. Available from: https://www.research.manchester.ac.uk/portal/en/theses/assessment-of-apolipoprotein-e-derived-peptides-as-novel-antimicrobials-for-the-coating-of-biomedical-devices(86d1dcbb-33f8-4ea4-bec0-9f07b97c29b6).html ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.734200.

Council of Science Editors:

Forbes S. Assessment of apolipoprotein E derived peptides as novel antimicrobials for the coating of biomedical devices. [Doctoral Dissertation]. University of Manchester; 2013. Available from: https://www.research.manchester.ac.uk/portal/en/theses/assessment-of-apolipoprotein-e-derived-peptides-as-novel-antimicrobials-for-the-coating-of-biomedical-devices(86d1dcbb-33f8-4ea4-bec0-9f07b97c29b6).html ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.734200

Indian Institute of Science

5. Arunagiri, Srigowtham. Assessment of University Technology Transfer Efficiency in the Context of Medical Device Technologies.

Degree: 2018, Indian Institute of Science

URL: http://etd.iisc.ernet.in/2005/3850 ; http://etd.iisc.ernet.in/abstracts/4722/G28540-Abs.pdf

► Data to understand the inventiveness and technology transfer process for medical devices in India is lacking and majority of medical devices are imported. The presence… (more)

Subjects/Keywords: University Technology Transfer; Technology Transfer, Medical Device; Medical Device Research; Medical Device Technology Patents; Universities’ Patents; Medical Device Patents (MDU); Management

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Arunagiri, S. (2018). Assessment of University Technology Transfer Efficiency in the Context of Medical Device Technologies. (Thesis). Indian Institute of Science. Retrieved from http://etd.iisc.ernet.in/2005/3850 ; http://etd.iisc.ernet.in/abstracts/4722/G28540-Abs.pdf

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Arunagiri, Srigowtham. “Assessment of University Technology Transfer Efficiency in the Context of Medical Device Technologies.” 2018. Thesis, Indian Institute of Science. Accessed December 13, 2019. http://etd.iisc.ernet.in/2005/3850 ; http://etd.iisc.ernet.in/abstracts/4722/G28540-Abs.pdf.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Arunagiri, Srigowtham. “Assessment of University Technology Transfer Efficiency in the Context of Medical Device Technologies.” 2018. Web. 13 Dec 2019.

Vancouver:

Arunagiri S. Assessment of University Technology Transfer Efficiency in the Context of Medical Device Technologies. [Internet] [Thesis]. Indian Institute of Science; 2018. [cited 2019 Dec 13]. Available from: http://etd.iisc.ernet.in/2005/3850 ; http://etd.iisc.ernet.in/abstracts/4722/G28540-Abs.pdf.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Arunagiri S. Assessment of University Technology Transfer Efficiency in the Context of Medical Device Technologies. [Thesis]. Indian Institute of Science; 2018. Available from: http://etd.iisc.ernet.in/2005/3850 ; http://etd.iisc.ernet.in/abstracts/4722/G28540-Abs.pdf

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Delft University of Technology

6. Op de Macks, F.L. Development of a medical device for diagnosis and treatment of pelvic floor dysfunctions:.

Degree: 2011, Delft University of Technology

URL: http://resolver.tudelft.nl/uuid:72ad9284-cb6c-42d7-9c9c-b09bd77803ec

► This graduation thesis describes the development of a system for the diagnosis and treatment of Pelvic Floor Dysfunctions, such as urinary incontinence, bowel problems, pain,… (more)

▼ This graduation thesis describes the development of a system for the diagnosis and treatment of Pelvic Floor Dysfunctions, such as urinary incontinence, bowel problems, pain, pelvic prolapse and/or sexual dysfunction. The assignment was initiated by MAXAM Medical, a start-up company consisting of Fiebke Op de Macks (author of this thesis) and ir. Jeroen Voorham. Suffering from Pelvic Floor Dysfunction can be very disabling and has an enormous impact on the patient’s Quality of Life. Currently over 180M people in Western countries suffer from a Pelvic Floor Dysfunction. A possible treatment method for these dysfunctions is Pelvic Floor Physiotherapy. MAXAM Medical is developing a system for diagnosis and treatment of Pelvic Floor Dysfunctions, which will assist Pelvic Floor Physiotherapists. As a result of this graduation thesis, this system will aid the process in an accurate and effective manner, providing innovative and qualitative health care. To develop a system that closely meets end-users’ needs and requirements, a Human Centered Design approach was used. Feedback from future end-users was actively used in the analysis, design and simulation phases of the project. During an analysis of currently used diagnosis and treatment equipment, the functions of Pelvic Floor Physiotherapists, their habits and problems became clear, providing valuable design input. This input was used for the system development, during the design phase of this project. As part of an iterative process the design was thoroughly tested with the help of future end-users, which resulted in a system that meets the express needs of the market. In the past decade, it has become apparent that usability alone does not provide people with everything they want when it comes to (new) products. People want products and services that add value to their daily lives. As products mature, they not only become more useful and usable tools, but they also require other qualities to be (commercially) more distinctive and satisfying. An entirely new user experience was created in this graduation thesis to meet these requirements. To be able to develop this new user experience, the Service, Technology, Organization and Finance (STOF) method was used. It is a design method that is developed especially for the creation of successful services and offers a step-by-step approach towards creating a balanced and secure business model. To conclude the thesis, a market analysis was performed of Europe and North-America, identifying the most interesting market entry countries. A strategic plan that MAXAM Medical should devise in order to achieve a successful market entry is proposed, together with recommendations for continuing innovation, development and testing of new functions to keep the system user’s experience and output at a high level. Advisors/Committee Members: Van Heur, R.J.H.G., Freudenthal, A., Pelger, R.C.M..

Subjects/Keywords: pelvic floor dysfunction; medical device

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Op de Macks, F. L. (2011). Development of a medical device for diagnosis and treatment of pelvic floor dysfunctions:. (Masters Thesis). Delft University of Technology. Retrieved from http://resolver.tudelft.nl/uuid:72ad9284-cb6c-42d7-9c9c-b09bd77803ec

Chicago Manual of Style (16^th Edition):

Op de Macks, F L. “Development of a medical device for diagnosis and treatment of pelvic floor dysfunctions:.” 2011. Masters Thesis, Delft University of Technology. Accessed December 13, 2019. http://resolver.tudelft.nl/uuid:72ad9284-cb6c-42d7-9c9c-b09bd77803ec.

MLA Handbook (7^th Edition):

Op de Macks, F L. “Development of a medical device for diagnosis and treatment of pelvic floor dysfunctions:.” 2011. Web. 13 Dec 2019.

Vancouver:

Op de Macks FL. Development of a medical device for diagnosis and treatment of pelvic floor dysfunctions:. [Internet] [Masters thesis]. Delft University of Technology; 2011. [cited 2019 Dec 13]. Available from: http://resolver.tudelft.nl/uuid:72ad9284-cb6c-42d7-9c9c-b09bd77803ec.

Council of Science Editors:

Op de Macks FL. Development of a medical device for diagnosis and treatment of pelvic floor dysfunctions:. [Masters Thesis]. Delft University of Technology; 2011. Available from: http://resolver.tudelft.nl/uuid:72ad9284-cb6c-42d7-9c9c-b09bd77803ec

Indian Institute of Science

7. Rekha, G Naga. An Exploratory Study of Indian Medical Device Clinical Trials : Landscaping and Assessment of Challenges.

Degree: 2016, Indian Institute of Science

URL: http://etd.iisc.ernet.in/2005/3812 ; http://etd.iisc.ernet.in/abstracts/4683/G27761-Abs.pdf

► The present day world has been experiencing rapid technological advancement on the one hand and increasing number of diseases afflicting the human beings on the… (more)

▼ The present day world has been experiencing rapid technological advancement on the one hand and increasing number of diseases afflicting the human beings on the other. To deal with the later, medical devices are innovated and introduced in to the market (making use of the technological advancements), on a continuous basis across the world. However, taking an innovated medical device to the market poses innumerable challenges and therefore, these have to be clinically trialled before its launch to ensure safety and efficacy. Of late, India has emerged as one of the preferred destinations to carry out clinical studies due to numerous advantages, primarily its diverse human gene pool and cost-competitiveness. However, there is very little understanding on the landscape of medical devices clinically trialled in India. It is to throw light on this critical issue with respect to the selection of participants in the clinical trial process, selection of locations and determination of trial duration that the present study has been carried out. In addition, the role of patents associated with the introduction of new medical devices in relation to the key challenges is examined. Furthermore, we studied the characteristics of clinical trials by industry and non-industry sponsors and between cardiovascular and other disease related trials. The present study has been carried out based on secondary data covering 108 medical device clinical trial registrations accessed from Clinical Trial Registry of India (CTRI) database pertaining to the period 2008-2014. At the outset, the pattern of trials related to the most prominent diseases such as cardiology and cardiovascular diseases and those which are invasive and non-invasive are examined. Our findings indicate that almost 50% of the trials are related to diseases of cardiology, cardiovascular diseases and those which are invasive in nature. For studying the patenting aspect, we proposed a conceptual grouping of sponsors as Incumbent, Potential Entrant and Supporter, based on their patent holdings in the domestic market and in PCT (Patent Cooperation Treaty) filings. Patents owned by Primary Sponsor (PS) showed significant variations in their clinical trial characteristics particularly the invasiveness of device, disease type, locations and participants. Three quantitative models are developed to identify the factors that influence the selection of number of participants, locations and time taken to execute medical device clinical trials using multivariate statistical techniques. The results of the three conceptual models on number of participants, locations and trial duration showed invasiveness of device and disease type playing significant roles in all the three models. The number of PCTs owned by PS was found to be influential in selecting the number of locations and participants but not the patents owned in IPO (Indian Patent Office). We also observed significant differences between industry and non-industry sponsors in terms of their clinical trial characteristics. The findings… Advisors/Committee Members: Bala Subrahmanya, M H.

Subjects/Keywords: Indian Health Care Industry; Medical Device Patenting; Medical Device Clinical Trail -India; Indian Medical Devices Industry; Medical Device Clinical Trials; Medical Device Clinical Trial Landscape; Management

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Rekha, G. N. (2016). An Exploratory Study of Indian Medical Device Clinical Trials : Landscaping and Assessment of Challenges. (Thesis). Indian Institute of Science. Retrieved from http://etd.iisc.ernet.in/2005/3812 ; http://etd.iisc.ernet.in/abstracts/4683/G27761-Abs.pdf

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Rekha, G Naga. “An Exploratory Study of Indian Medical Device Clinical Trials : Landscaping and Assessment of Challenges.” 2016. Thesis, Indian Institute of Science. Accessed December 13, 2019. http://etd.iisc.ernet.in/2005/3812 ; http://etd.iisc.ernet.in/abstracts/4683/G27761-Abs.pdf.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Rekha, G Naga. “An Exploratory Study of Indian Medical Device Clinical Trials : Landscaping and Assessment of Challenges.” 2016. Web. 13 Dec 2019.

Vancouver:

Rekha GN. An Exploratory Study of Indian Medical Device Clinical Trials : Landscaping and Assessment of Challenges. [Internet] [Thesis]. Indian Institute of Science; 2016. [cited 2019 Dec 13]. Available from: http://etd.iisc.ernet.in/2005/3812 ; http://etd.iisc.ernet.in/abstracts/4683/G27761-Abs.pdf.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Rekha GN. An Exploratory Study of Indian Medical Device Clinical Trials : Landscaping and Assessment of Challenges. [Thesis]. Indian Institute of Science; 2016. Available from: http://etd.iisc.ernet.in/2005/3812 ; http://etd.iisc.ernet.in/abstracts/4683/G27761-Abs.pdf

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Illinois – Urbana-Champaign

8. Lee, Yun Young. Safe medical device interaction rules.

Degree: MS, 0112, 2011, University of Illinois – Urbana-Champaign

URL: http://hdl.handle.net/2142/18451

► The advent of computerized medical devices has resulted in better accuracy and increased safety for patients and clinicians, yet medical accidents are still not uncommon.… (more)

Subjects/Keywords: Medical Informatics; Safety; MDPnP; Medical Devices; Medical Device Interaction.

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Lee, Y. Y. (2011). Safe medical device interaction rules. (Thesis). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/18451

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Lee, Yun Young. “Safe medical device interaction rules.” 2011. Thesis, University of Illinois – Urbana-Champaign. Accessed December 13, 2019. http://hdl.handle.net/2142/18451.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Lee, Yun Young. “Safe medical device interaction rules.” 2011. Web. 13 Dec 2019.

Vancouver:

Lee YY. Safe medical device interaction rules. [Internet] [Thesis]. University of Illinois – Urbana-Champaign; 2011. [cited 2019 Dec 13]. Available from: http://hdl.handle.net/2142/18451.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Lee YY. Safe medical device interaction rules. [Thesis]. University of Illinois – Urbana-Champaign; 2011. Available from: http://hdl.handle.net/2142/18451

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

NSYSU

9. Liu, Yin-Tse. Study of the Information System Application in Consignment Inventory Management: A Case of the Logistic Service Provider.

Degree: Master, EMBA, 2014, NSYSU

URL: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0631114-091107

► In 1995, the National Health Insurance (NHI) governed by the Ministry of Health and Welfare in Taiwan was instituted nationwide. Since the time NHI was… (more)

▼ In 1995, the National Health Insurance (NHI) governed by the Ministry of Health and Welfare in Taiwan was instituted nationwide. Since the time NHI was conceived, the budget has been running a deficit, frequently relying on government assistance with its financial problems. To solve the problems, the Ministry of Health and Welfare begin to cut costs, in ways which it changed its current reimbursement structure of current fee-for-service basis reimbursement to same pre-determined amount in the same diagnosis related groups reimbursement. This switch was known as Taiwan DRG. The Taiwan DRG system has been controversial. Due to its nature of limiting the reimbursements, the hospitals will now try to limit costs to a minimum, therefore limiting the patients for proper care. Since medical devices are responsible for 30% to 40% of hospital costs per DRG reimbursement, hospitals have now the incentive to specifically lower costs in medical devices. One way to lower costs in this area is to use the consignment method in managing medical device inventory. This means medical device suppliers now face a new set of problems with consignment inventory management: discrepancies in inventory, product availability, and overall efficiency in logistics. Suppliers still lack the experience and knowledge to properly execute consignment management with hospitals under the Taiwan DRG system. DKSH Healthcare is the leading partner for hospitals seeking to stabilize and grow. DKSH offer services ranging from market expansion services, and marketing and sales to physical distribution. Since 2008, our team at DKSH has accumulated many years of consignment management experience, leveraging DKSHâs high tech approach in using the latest tech solutions to solve problems for its partners. This thesis will observe and analyze DKSH Healthcareâs methods and solutions for consignment management problems. The research and efforts spent with hospitals and suppliers from DHSK are expected to benefit everyone with a more efficient and effective process in consignment management for medical deceives. DKSH will continue to discover new solutions and efficiencies for consignment inventory management as it partners with more hospitals and suppliers in the future. Advisors/Committee Members: Pei-How Huang (committee member), Tsai, Hsien-tang (chair), Cher-Min Fong (chair).

Subjects/Keywords: Barcode; RFID; Inventory; Consignment; Medical Device

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Liu, Y. (2014). Study of the Information System Application in Consignment Inventory Management: A Case of the Logistic Service Provider. (Thesis). NSYSU. Retrieved from http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0631114-091107

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Liu, Yin-Tse. “Study of the Information System Application in Consignment Inventory Management: A Case of the Logistic Service Provider.” 2014. Thesis, NSYSU. Accessed December 13, 2019. http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0631114-091107.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Liu, Yin-Tse. “Study of the Information System Application in Consignment Inventory Management: A Case of the Logistic Service Provider.” 2014. Web. 13 Dec 2019.

Vancouver:

Liu Y. Study of the Information System Application in Consignment Inventory Management: A Case of the Logistic Service Provider. [Internet] [Thesis]. NSYSU; 2014. [cited 2019 Dec 13]. Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0631114-091107.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Liu Y. Study of the Information System Application in Consignment Inventory Management: A Case of the Logistic Service Provider. [Thesis]. NSYSU; 2014. Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0631114-091107

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

NSYSU

10. Yang, Ya-Wen. Designs of Novel Antennas and Artificial Electromagnetic Cover Layers for Medical Implant Communication Systems.

Degree: Master, Electrical Engineering, 2012, NSYSU

URL: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0716112-161948

► In this thesis, we design novel implantable antennas for medical implant communication systems and it could operate with the metamaterial which is the artificial electromagnetic… (more)

Subjects/Keywords: Implantable antenna; Implantable medical device (IMD); Metamaterial

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APA (6^th Edition):

Yang, Y. (2012). Designs of Novel Antennas and Artificial Electromagnetic Cover Layers for Medical Implant Communication Systems. (Thesis). NSYSU. Retrieved from http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0716112-161948

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Yang, Ya-Wen. “Designs of Novel Antennas and Artificial Electromagnetic Cover Layers for Medical Implant Communication Systems.” 2012. Thesis, NSYSU. Accessed December 13, 2019. http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0716112-161948.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Yang, Ya-Wen. “Designs of Novel Antennas and Artificial Electromagnetic Cover Layers for Medical Implant Communication Systems.” 2012. Web. 13 Dec 2019.

Vancouver:

Yang Y. Designs of Novel Antennas and Artificial Electromagnetic Cover Layers for Medical Implant Communication Systems. [Internet] [Thesis]. NSYSU; 2012. [cited 2019 Dec 13]. Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0716112-161948.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Yang Y. Designs of Novel Antennas and Artificial Electromagnetic Cover Layers for Medical Implant Communication Systems. [Thesis]. NSYSU; 2012. Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0716112-161948

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

NSYSU

11. Wang, Kuan-Ju. The Study on Integration Strategy of Medical Device Industry in Taiwan â The Case of the Joint Venture Project between Excelsior and Sinopharm.

Degree: Master, EMBA, 2012, NSYSU

URL: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0730112-233051

► Up to date, the biggest challenge of Taiwanâs medical device industry is that the major market was occupied by international companies which directly hold the… (more)

▼ Up to date, the biggest challenge of Taiwanâs medical device industry is that the major market was occupied by international companies which directly hold the research and development, manufacture and selling. In addition, the medical devices have the properties in producing few products with diverse forms, research and development with complicating technology and high threshold in the application of product license. As the domestic market in Taiwan is quite small, small and medium-sized enterprises are the mainscales of Enterprises' Operating Capacity here. The chosen of joint venture of two enterprises through strategic cooperation may be one solution to survive in such ecology and play their good in order to create the core value supporting the goal of sustainability for business management. According to the policy considerations, the biotechnology and medical treatment industry are as the important issue in ECFA agreement between Taiwan and mainland China in 2010. All together, there are hundreds and thousands of opportunities for merger, acquisitions and strategic alliance within this industyin the foreseeable future. This study was based on the study case of the 32-years-old Excelsior. It began with dialysis market-oriented industry and then branched out into all the medical equipment industry. Through strategic co-operation, it expanded to become a medical integration platform providing services regarding to comprehensive roles from trade to hospital management. It accommodates the full range of downstream applications for Medical Engineering Services, Pharmaceutical warehousing and logistics, Procurement and supply, and health care management. Although the Excelsior has been to China ten years ago, it fails to succeed and returns back. In 2011, Excelsior makes the joining venture cooperates with the biggest pharmaceutic distributor in China, Sinopharm focuses on four major medicalterritory that are dialysis, medical cosmetic, dentistry and health-check, and approaches the 5000 billion market in Health-Care-Reform offered by the 12th-Five year-plan of China. However, this time it attempts a come back to become the most valuable of the integrated medical and health industry in Asia. Through study on the history and outcome of joining venture between Excelsior and Sinopharm in the field of medical device industry, this thesis addresses factors that will affect business innovation integrated and product line expression. Through studying the case of Excelsior on its background, history of Strategic cooperationã integrated product lineãfinancial management and experience of success or failure in the past may provide the reference for the development of Taiwan medical device industry. Advisors/Committee Members: Jung-Ing Huang (committee member), Min-Hsin Huang (chair), Huang,Jen-Jsung (chair), Ying-Chun Li (committee member).

Subjects/Keywords: Sinopharm; Excelsior; Joint venture; medical device industry

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APA (6^th Edition):

Wang, K. (2012). The Study on Integration Strategy of Medical Device Industry in Taiwan â The Case of the Joint Venture Project between Excelsior and Sinopharm. (Thesis). NSYSU. Retrieved from http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0730112-233051

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Wang, Kuan-Ju. “The Study on Integration Strategy of Medical Device Industry in Taiwan â The Case of the Joint Venture Project between Excelsior and Sinopharm.” 2012. Thesis, NSYSU. Accessed December 13, 2019. http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0730112-233051.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Wang, Kuan-Ju. “The Study on Integration Strategy of Medical Device Industry in Taiwan â The Case of the Joint Venture Project between Excelsior and Sinopharm.” 2012. Web. 13 Dec 2019.

Vancouver:

Wang K. The Study on Integration Strategy of Medical Device Industry in Taiwan â The Case of the Joint Venture Project between Excelsior and Sinopharm. [Internet] [Thesis]. NSYSU; 2012. [cited 2019 Dec 13]. Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0730112-233051.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Wang K. The Study on Integration Strategy of Medical Device Industry in Taiwan â The Case of the Joint Venture Project between Excelsior and Sinopharm. [Thesis]. NSYSU; 2012. Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0730112-233051

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Akron

12. Quang, Tri T. Development of Compact Multimodal Optical Imaging and Medical Assessment Systems.

Degree: MSin Engineering, Biomedical Engineering, 2015, University of Akron

URL: http://rave.ohiolink.edu/etdc/view?acc_num=akron1452533192

► Development of medical devices in a small size, lightweight and low cost design is attracting growing attentions in healthcare. Compact, portable and easy to use… (more)

▼ Development of medical devices in a small size, lightweight and low cost design is attracting growing attentions in healthcare. Compact, portable and easy to use systems that can solve a specific medical or health related problem and also offer customization and integration abilities to perform multi-functional features are appealing options to clinicians. In the thesis, two proposed systems for multimodal optical imaging and medical assessment are presented. The first part describes a novel mobile eye tracking based traumatic brain injury assessment system that was developed to detect traumatic brain injuries (TBIs). Integrated visual tracking and visuomotor tests were developed to assess TBI quickly and conveniently. The system can be operated in mobile devices such as tablets and cell phones and enables videooculographic and visuomotor assessment of patients based on a target-oriented visual tracking-touching synchronization. Two simulation tests were utilized to test system performance in detection of impaired eye movement. Statistically significant differences between the pathological simulation and normal cases were found in the concentration test (P<.0001), the horizontal (P=.0005) and circular movement tests (P=.0013) with a statistical power of 80.5%. 100% touch success and shorter time in performing the visuomotor test were obtained in normal cases. The second part describes the development of a Fluorescence Imaging Topology Scanning (FITS) system. Clinically, conventional imaging modalities such as positron emission tomography, x-ray computed tomography and fluorescence molecular tomography can provide useful data to clinicians. However, these tomographic imaging modalities are not optimized for intraoperative settings due to the slow scan time and the lack of real time update which is crucial for guiding surgery. The FITS system can offer color reflectance imaging, fluorescence imaging and surface topology scanning capabilities for three-dimensional multimodal imaging. In this study, system characterization, ex vivo image-guided surgeries in chicken and in vivo multimodal imaging of sentinel lymph nodes (SLNs) in mice using FITS and PET/CT were conducted to validate the capabilities of the system in providing multimodal imaging for surgery. The prototype offers a sub-millimeter lateral resolution, a sub-millimeter depth resolution for topology and 10nM fluorescence detection sensitivity. Fluorescence labeled targets were successfully identified and highlighted. Lymph vessels (diameter < 0.3mm) and the SLNs were imaged (average SBR of the lymph node = 6.09 ± 0.6). The system is compact and portable, and thus suitable for deployment in the operating room. These systems have demonstrated great potential in supporting clinical decision making and guiding medical assessments. Advisors/Committee Members: Liu, Yang (Advisor).

Subjects/Keywords: Biomedical Engineering; medical device; TBI; FITS

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APA (6^th Edition):

Quang, T. T. (2015). Development of Compact Multimodal Optical Imaging and Medical Assessment Systems. (Masters Thesis). University of Akron. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=akron1452533192

Chicago Manual of Style (16^th Edition):

Quang, Tri T. “Development of Compact Multimodal Optical Imaging and Medical Assessment Systems.” 2015. Masters Thesis, University of Akron. Accessed December 13, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=akron1452533192.

MLA Handbook (7^th Edition):

Quang, Tri T. “Development of Compact Multimodal Optical Imaging and Medical Assessment Systems.” 2015. Web. 13 Dec 2019.

Vancouver:

Quang TT. Development of Compact Multimodal Optical Imaging and Medical Assessment Systems. [Internet] [Masters thesis]. University of Akron; 2015. [cited 2019 Dec 13]. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=akron1452533192.

Council of Science Editors:

Quang TT. Development of Compact Multimodal Optical Imaging and Medical Assessment Systems. [Masters Thesis]. University of Akron; 2015. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=akron1452533192

University of California – Berkeley

13. Kanjanapas, Kan. Human Mechatronics Considerations of Sensing and Actuation Systems for Rehabilitation Application.

Degree: Mechanical Engineering, 2014, University of California – Berkeley

URL: http://www.escholarship.org/uc/item/8vg7w7bp

► With the predicted increase in worldwide elderly population in the future and already significant populations of disabled people, assistive technologies and rehabilitation devices are demanded… (more)

Subjects/Keywords: Mechanical engineering; Control; Mechatronics; Medical Device; Rehabilitation

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APA (6^th Edition):

Kanjanapas, K. (2014). Human Mechatronics Considerations of Sensing and Actuation Systems for Rehabilitation Application. (Thesis). University of California – Berkeley. Retrieved from http://www.escholarship.org/uc/item/8vg7w7bp

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Kanjanapas, Kan. “Human Mechatronics Considerations of Sensing and Actuation Systems for Rehabilitation Application.” 2014. Thesis, University of California – Berkeley. Accessed December 13, 2019. http://www.escholarship.org/uc/item/8vg7w7bp.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Kanjanapas, Kan. “Human Mechatronics Considerations of Sensing and Actuation Systems for Rehabilitation Application.” 2014. Web. 13 Dec 2019.

Vancouver:

Kanjanapas K. Human Mechatronics Considerations of Sensing and Actuation Systems for Rehabilitation Application. [Internet] [Thesis]. University of California – Berkeley; 2014. [cited 2019 Dec 13]. Available from: http://www.escholarship.org/uc/item/8vg7w7bp.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Kanjanapas K. Human Mechatronics Considerations of Sensing and Actuation Systems for Rehabilitation Application. [Thesis]. University of California – Berkeley; 2014. Available from: http://www.escholarship.org/uc/item/8vg7w7bp

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Illinois – Chicago

14. Zellander, Amelia. Designing Novel Biomaterials for Cornea Replacement.

Degree: 2013, University of Illinois – Chicago

URL: http://hdl.handle.net/10027/10367

► Artificial corneas, also known as keratoprostheses (KPros), are an alternative cornea replacement therapy when donor cornea is either inappropriate or inaccessible to a patient. KPro… (more)

▼ Artificial corneas, also known as keratoprostheses (KPros), are an alternative cornea replacement therapy when donor cornea is either inappropriate or inaccessible to a patient. KPro recipients often have preexisting ocular diseases, ocular tissue injury, or a history of corneal graft failure. While a number of KPro models are available on the market, each fails to completely address one or more of the following vital parameters: host integration, mass transport, tissue epithelialization, or innervation. This study presents biomaterials that can potentially improve stable host integration and long term vision restoration. KPros made with poly (2-hydroxyethyl methacrylate) (PHEMA) - poly (methyl methacrylate) (PMMA) (PHEMA-PMMA) and copolymers made with of PHEMA and PEG (polyethylene glycol) are structurally, mechanically, and biologically appropriate for corneal replacement. The center region of the KPro is optically transparent to permit vision; the outer rim of the device is porous to permit tissue ingrowth. Following the addition of cell adhesion components (collagen type I) human corneal fibroblasts proliferated on the porous skirt structures. Mechanical tensile data indicated that the KPro structures are strong enough to resist rupture under the mechanical forces of the eye. PHEMA-PMMA based KPros are mechanically stable enough to be sutured in as full thickness corneal replacement devices. PHEMA and PEG copolymers, mechanically weaker than PHEMA-PMMA, are better suited for suture-less cornea replacement strategies. SEM and Micro CT data show that the pores in the skirts are large enough to permit cell ingrowth. In vivo, healthy tissues penetrate the voids of the porous copolymers. Since diseased ocular tissue is more reluctant to colonize synthetic biomaterials compared to natural-synthetic hybrids, the each skirt’s amenability to cell adhesion component addition is vital to the survival of the KPro in the target patient population. A cell adhesive KPro skirt with a high density of cell permeable pores and physiologically relevant mass transport could potentially facilitate the stable integration of a KPro into ocular tissue. Advisors/Committee Members: Cho, Michael (advisor).

Subjects/Keywords: cornea; keratoprosthesis; polymer; tissue engineering; medical device

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APA (6^th Edition):

Zellander, A. (2013). Designing Novel Biomaterials for Cornea Replacement. (Thesis). University of Illinois – Chicago. Retrieved from http://hdl.handle.net/10027/10367

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Zellander, Amelia. “Designing Novel Biomaterials for Cornea Replacement.” 2013. Thesis, University of Illinois – Chicago. Accessed December 13, 2019. http://hdl.handle.net/10027/10367.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Zellander, Amelia. “Designing Novel Biomaterials for Cornea Replacement.” 2013. Web. 13 Dec 2019.

Vancouver:

Zellander A. Designing Novel Biomaterials for Cornea Replacement. [Internet] [Thesis]. University of Illinois – Chicago; 2013. [cited 2019 Dec 13]. Available from: http://hdl.handle.net/10027/10367.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Zellander A. Designing Novel Biomaterials for Cornea Replacement. [Thesis]. University of Illinois – Chicago; 2013. Available from: http://hdl.handle.net/10027/10367

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Delft University of Technology

15. Vlieland, J.A. Emma - Improving the patient's therapy adherence by using a smart wristband device:.

Degree: 2014, Delft University of Technology

URL: http://resolver.tudelft.nl/uuid:a5d09674-3b84-4adf-a339-ee0b87d0005e

► This thesis describes the design process and end results of my graduation internship at Medicine Men, a startup which develops medical applications for wearable devices.… (more)

Subjects/Keywords: mHealth; smartwatch; medical device; therapy adherence

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Vlieland, J. A. (2014). Emma - Improving the patient's therapy adherence by using a smart wristband device:. (Masters Thesis). Delft University of Technology. Retrieved from http://resolver.tudelft.nl/uuid:a5d09674-3b84-4adf-a339-ee0b87d0005e

Chicago Manual of Style (16^th Edition):

Vlieland, J A. “Emma - Improving the patient's therapy adherence by using a smart wristband device:.” 2014. Masters Thesis, Delft University of Technology. Accessed December 13, 2019. http://resolver.tudelft.nl/uuid:a5d09674-3b84-4adf-a339-ee0b87d0005e.

MLA Handbook (7^th Edition):

Vlieland, J A. “Emma - Improving the patient's therapy adherence by using a smart wristband device:.” 2014. Web. 13 Dec 2019.

Vancouver:

Vlieland JA. Emma - Improving the patient's therapy adherence by using a smart wristband device:. [Internet] [Masters thesis]. Delft University of Technology; 2014. [cited 2019 Dec 13]. Available from: http://resolver.tudelft.nl/uuid:a5d09674-3b84-4adf-a339-ee0b87d0005e.

Council of Science Editors:

Vlieland JA. Emma - Improving the patient's therapy adherence by using a smart wristband device:. [Masters Thesis]. Delft University of Technology; 2014. Available from: http://resolver.tudelft.nl/uuid:a5d09674-3b84-4adf-a339-ee0b87d0005e

Delft University of Technology

16. Laarhoven, K.J. Hornet Fixation Device:.

Degree: 2016, Delft University of Technology

URL: http://resolver.tudelft.nl/uuid:e2b822fe-a742-4cdb-b2b1-3fcddcc0d9b1

► Laparoscopic suturing can be very time consuming and frustrating for inexperienced surgeons. It is one of the hardest actions to perform in a laparoscopic fashion,… (more)

Subjects/Keywords: laparoscopy; medical; device; suturing; design; 5mm; instrument

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APA (6^th Edition):

Laarhoven, K. J. (2016). Hornet Fixation Device:. (Masters Thesis). Delft University of Technology. Retrieved from http://resolver.tudelft.nl/uuid:e2b822fe-a742-4cdb-b2b1-3fcddcc0d9b1

Chicago Manual of Style (16^th Edition):

Laarhoven, K J. “Hornet Fixation Device:.” 2016. Masters Thesis, Delft University of Technology. Accessed December 13, 2019. http://resolver.tudelft.nl/uuid:e2b822fe-a742-4cdb-b2b1-3fcddcc0d9b1.

MLA Handbook (7^th Edition):

Laarhoven, K J. “Hornet Fixation Device:.” 2016. Web. 13 Dec 2019.

Vancouver:

Laarhoven KJ. Hornet Fixation Device:. [Internet] [Masters thesis]. Delft University of Technology; 2016. [cited 2019 Dec 13]. Available from: http://resolver.tudelft.nl/uuid:e2b822fe-a742-4cdb-b2b1-3fcddcc0d9b1.

Council of Science Editors:

Laarhoven KJ. Hornet Fixation Device:. [Masters Thesis]. Delft University of Technology; 2016. Available from: http://resolver.tudelft.nl/uuid:e2b822fe-a742-4cdb-b2b1-3fcddcc0d9b1

Vanderbilt University

17. Garbin, Nicolo. Endoscopic and magnetic actuation for miniature lifesaving devices.

Degree: PhD, Mechanical Engineering, 2019, Vanderbilt University

URL: http://etd.library.vanderbilt.edu/available/etd-02052019-125544/ ;

► The need for medical technologies that improve patient access to diagnostic techniques and treat pathological conditions in a minimally invasive approach is capitalized in this… (more)

▼ The need for medical technologies that improve patient access to diagnostic techniques and treat pathological conditions in a minimally invasive approach is capitalized in this dissertation with the development, characterization, and testing toward clinical use of a series of endoscopically and magnetically actuated devices. The ï¬rst half of this dissertation proposed an alternative solution to the use of conventional ï¬exible endoscopy for the diagnosis of the upper gastrointestinal tract. The proposed disposable ï¬exible endoscope is, compared to conventional endoscopy, more cost effective, intuitive, and hygienic. The deviceâs endoscopic tip is controlled via pneumatic actuation. Modeling was inspired from multi-backbone continuum robots, and two user interfaces were investigated. First, a robotic platform is used to tackle the closed-loop control problem, then a novel user interface allows direct user-to-task mapping via pure mechanical actuation. The effectiveness of the latter approach was further assessed during in-vivo and cadaveric trials, ease of use was instead determined via approved user studies that involved medical providers with different backgrounds. The device is currently undergoing design freeze toward human trials. The second half of this dissertation exploits robotic control of magnetic actuation to develop therapeutic medical devices with applications in minimally invasive surgery and subcutaneous implants. A laparoscopic retractor able to retract up to 10 times its own weight, and laparoscopic camera with an hemispherical workspace via a compact unique magnetic coupling, decrease by two the number of incisions needed for abdominal surgery. These technologies decrease trauma, pain, and risk of infection for the patients, and offer better visibility, surgical workspace access, and decrease trocar crowding for the surgeons. Then, a subcutaneously implantable pump developed for the treatment of refractory ascites removes a large quantity of ï¬uids without the need of on-board electronics. All of these devices were tested during ex-vivo and in-vivo trials highlighting the advantages and effectiveness of using magnetic coupling for clinically relevant therapeutic tasks. Advisors/Committee Members: Pietro Valdastri (chair), Keith L. Obstein (chair), Thomas J. Withrow (committee member), Robert J. Webster III (committee member), Nabil Simaan (committee member).

Subjects/Keywords: magnetic actuation; disposable; robotic; medical device

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Garbin, N. (2019). Endoscopic and magnetic actuation for miniature lifesaving devices. (Doctoral Dissertation). Vanderbilt University. Retrieved from http://etd.library.vanderbilt.edu/available/etd-02052019-125544/ ;

Chicago Manual of Style (16^th Edition):

Garbin, Nicolo. “Endoscopic and magnetic actuation for miniature lifesaving devices.” 2019. Doctoral Dissertation, Vanderbilt University. Accessed December 13, 2019. http://etd.library.vanderbilt.edu/available/etd-02052019-125544/ ;.

MLA Handbook (7^th Edition):

Garbin, Nicolo. “Endoscopic and magnetic actuation for miniature lifesaving devices.” 2019. Web. 13 Dec 2019.

Vancouver:

Garbin N. Endoscopic and magnetic actuation for miniature lifesaving devices. [Internet] [Doctoral dissertation]. Vanderbilt University; 2019. [cited 2019 Dec 13]. Available from: http://etd.library.vanderbilt.edu/available/etd-02052019-125544/ ;.

Council of Science Editors:

Garbin N. Endoscopic and magnetic actuation for miniature lifesaving devices. [Doctoral Dissertation]. Vanderbilt University; 2019. Available from: http://etd.library.vanderbilt.edu/available/etd-02052019-125544/ ;

University of Toronto

18. Lam, Albert. Automation of a Multiplexed Microbead-based DNA Assay Platform.

Degree: 2015, University of Toronto

URL: http://hdl.handle.net/1807/69656

►

Microbead-based diagnostic technology has been explored in academia for over 30 years. As the technology matured, it became clear that this was a competitive platform… (more)

Subjects/Keywords: diagnostics; medical device; microfluidics; nanotechnology; 0541

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APA (6^th Edition):

Lam, A. (2015). Automation of a Multiplexed Microbead-based DNA Assay Platform. (Masters Thesis). University of Toronto. Retrieved from http://hdl.handle.net/1807/69656

Chicago Manual of Style (16^th Edition):

Lam, Albert. “Automation of a Multiplexed Microbead-based DNA Assay Platform.” 2015. Masters Thesis, University of Toronto. Accessed December 13, 2019. http://hdl.handle.net/1807/69656.

MLA Handbook (7^th Edition):

Lam, Albert. “Automation of a Multiplexed Microbead-based DNA Assay Platform.” 2015. Web. 13 Dec 2019.

Vancouver:

Lam A. Automation of a Multiplexed Microbead-based DNA Assay Platform. [Internet] [Masters thesis]. University of Toronto; 2015. [cited 2019 Dec 13]. Available from: http://hdl.handle.net/1807/69656.

Council of Science Editors:

Lam A. Automation of a Multiplexed Microbead-based DNA Assay Platform. [Masters Thesis]. University of Toronto; 2015. Available from: http://hdl.handle.net/1807/69656

University of Waterloo

19. Zhang, Shuo. Classification of Sleep Staging For Narcolepsy Assistive Device.

Degree: 2008, University of Waterloo

URL: http://hdl.handle.net/10012/3565

► Narcolepsy is a chronic neurological disorder caused by the brain’s inability to regulate sleep wake cycles normally [1]. Narcoleptic patients feel overwhelmingly tired and sleepy.… (more)

▼ Narcolepsy is a chronic neurological disorder caused by the brain’s inability to regulate sleep wake cycles normally [1]. Narcoleptic patients feel overwhelmingly tired and sleepy. They do not have the ability to carry out normal day time activities, such as work or study, hence proper treatment is essential. In order to provide an accurate diagnosis of the sleep disorder, physicians must analyze the sleep stages of the patient. Sleep staging analysis is the process of extracting sleep information with brain signals known as electrophysiological signals. There are three major electrophysiological signals: Electroencephalograms (EEG), Electro-oculograms (EOG), and Electromyograms (EMG). Through the three signals, physicians and technicians can classify the sleep stages. Although all three signals are important, most physicians and researchers agree that 95% of information can be extracted from EEG signal. With the current technology, patients must go to the hospital and sleep there over night to perform the sleep stage studies. Electrodes are placed on their scalp, eyelids and skin for this examination. Often patients feel that it is very inconvenient and time consuming. Moreover, the technicians are prone to make human errors during the classification of the sleep stages. These errors are a result of fatigue that the technicians experience while doing the long process of classification of the sleep stages, and the complexity and ambiguity of the rules to determine the sleep stages. Our research group has worked together to construct a portable device that will provide advice to the narcolepsy patient for activity planning and medication dosage. In addition, it provides fore-warning to the patients prior to an narcoleptic attack. This device will also perform real-time sleep analysis and alertness assessment through processing of electroencephalogram (EEG) signal. The classification accuracy is extremely important to the development of this device. With high accuracy of the classifier, treatment for the patients can be determined more accurately by the physicians. As a result, the main purpose of the research presented in this thesis is to analyze different classification methodology and to optimize the parameters of each technology to obtain the optimal sleep stage classification results. The thesis will also present the description of the portable device and its components used for the development of the prototype.

Subjects/Keywords: Medical Device Design

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APA (6^th Edition):

Zhang, S. (2008). Classification of Sleep Staging For Narcolepsy Assistive Device. (Thesis). University of Waterloo. Retrieved from http://hdl.handle.net/10012/3565

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Zhang, Shuo. “Classification of Sleep Staging For Narcolepsy Assistive Device.” 2008. Thesis, University of Waterloo. Accessed December 13, 2019. http://hdl.handle.net/10012/3565.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Zhang, Shuo. “Classification of Sleep Staging For Narcolepsy Assistive Device.” 2008. Web. 13 Dec 2019.

Vancouver:

Zhang S. Classification of Sleep Staging For Narcolepsy Assistive Device. [Internet] [Thesis]. University of Waterloo; 2008. [cited 2019 Dec 13]. Available from: http://hdl.handle.net/10012/3565.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Zhang S. Classification of Sleep Staging For Narcolepsy Assistive Device. [Thesis]. University of Waterloo; 2008. Available from: http://hdl.handle.net/10012/3565

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Queens University

20. Esau, Greg. Analysis and Design of Bearing Systems in Controlled Passive Energy Management (CPEM) Prosthetic Feet .

Degree: Mechanical and Materials Engineering, 2014, Queens University

URL: http://hdl.handle.net/1974/12439

► The overall goal of this study is to advance the availability of prosthetic devices for developing and post conflict regions by establishing a framework for… (more)

Subjects/Keywords: Analysis; Biomechanics; Design; Medical Device; Prosthetic foot

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APA (6^th Edition):

Esau, G. (2014). Analysis and Design of Bearing Systems in Controlled Passive Energy Management (CPEM) Prosthetic Feet . (Thesis). Queens University. Retrieved from http://hdl.handle.net/1974/12439

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Esau, Greg. “Analysis and Design of Bearing Systems in Controlled Passive Energy Management (CPEM) Prosthetic Feet .” 2014. Thesis, Queens University. Accessed December 13, 2019. http://hdl.handle.net/1974/12439.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Esau, Greg. “Analysis and Design of Bearing Systems in Controlled Passive Energy Management (CPEM) Prosthetic Feet .” 2014. Web. 13 Dec 2019.

Vancouver:

Esau G. Analysis and Design of Bearing Systems in Controlled Passive Energy Management (CPEM) Prosthetic Feet . [Internet] [Thesis]. Queens University; 2014. [cited 2019 Dec 13]. Available from: http://hdl.handle.net/1974/12439.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Esau G. Analysis and Design of Bearing Systems in Controlled Passive Energy Management (CPEM) Prosthetic Feet . [Thesis]. Queens University; 2014. Available from: http://hdl.handle.net/1974/12439

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Virginia Tech

21. Trent, Alexis Raven. Fabrication, Characterization and Cellular Interactions of Keratin Nanomaterial Coatings for Implantable Percutaneous Prosthetics.

Degree: PhD, Materials Science and Engineering, 2018, Virginia Tech

URL: http://hdl.handle.net/10919/94417

► Implantable medical devices face numerous complications when interfacing with soft tissue, and are plagued by negative responses from host tissue. One such class devices are… (more)

▼ Implantable medical devices face numerous complications when interfacing with soft tissue, and are plagued by negative responses from host tissue. One such class devices are percutaneous osseointegrated prosthetics (POP). POP consist of a bone anchored titanium post that extrudes through the skin and attaches to an external prosthetic. Compared to the traditional socket interface, POPs offer better stability, limb functionality, and osseoperception for both upper and lower prosthetic limbs. Although the POP surgery technique is well established, the main disadvantage to this technology remains the titanium (Ti) - skin interface. Some of the complications that can arise include epithelial downgrowth, mechanical tearing, and infection. Various types of coatings, surface structure, and antibiotic release technologies have been used to coat Ti in an effort to mitigate POP's associated obstacles, but these methods have failed to translate into published clinical studies and mainstream medical use. One potential solution may be to mimic an interface already found in the human body, the fingernail-skin interface, which is infection-free and mechanically stable. The same keratins that make up the cortex of human hair fibers are found in the fingernail. These cortical human hair keratins can be extracted and purified, and fingernail-specific dimeric complexes coated onto Ti surfaces using silane coupling chemistry. Keratin has been used in other studies for its cell adhesion and differentiation properties, and it has been suggested that the Leu-Asp-Val (LDV) amino acid motif is the primary site responsible for cellular attachment. In the present work, keratins extracted from human hair fibers and recombinant keratin nanomaterials (KN) were used to create biomimetic coatings on silanized Ti surfaces. These coatings were characterized and investigated for surface topography, elemental composition, cell adhesion motifs, and cell adhesion. Both keratin substrates showed the ability to create uniform coatings that retain a protein conformation that exhibits cell adhesion motifs. The coatings exhibit the ability to support cell adhesion of both epithelial and connective tissue cells. Application of fluid shear stress was used to test the mechanical adhesion strength of cells on keratin coatings. The structure, biochemical stability and sustained cellular adhesion of these coatings support keratin's capacity to provide a stable interface between POPs and skin. Side-by-side studies of extracted and recombinant keratins reveals that the recombinant form of these materials may provide distinct advantages for their use in POP devices. Overall, this study confirmed that a uniform, silane-coupled keratin coating was feasible. We demonstrated the substrates contain a biological function in terms of cellular adhesion and phenotypic changes in skin-relevant cells. These results support the biomimetic function of keratin on silanized Ti, which may provide a suitable coating to translate percutaneous medical device coating… Advisors/Committee Members: Van Dyke, Mark (committeechair), Goldstein, Aaron S (committee member), Whittington, Abby Rebecca (committee member), Foster, Earl Johan (committee member).

Subjects/Keywords: Biomimetic interface; medical device; protein surface modification

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Trent, A. R. (2018). Fabrication, Characterization and Cellular Interactions of Keratin Nanomaterial Coatings for Implantable Percutaneous Prosthetics. (Doctoral Dissertation). Virginia Tech. Retrieved from http://hdl.handle.net/10919/94417

Chicago Manual of Style (16^th Edition):

Trent, Alexis Raven. “Fabrication, Characterization and Cellular Interactions of Keratin Nanomaterial Coatings for Implantable Percutaneous Prosthetics.” 2018. Doctoral Dissertation, Virginia Tech. Accessed December 13, 2019. http://hdl.handle.net/10919/94417.

MLA Handbook (7^th Edition):

Trent, Alexis Raven. “Fabrication, Characterization and Cellular Interactions of Keratin Nanomaterial Coatings for Implantable Percutaneous Prosthetics.” 2018. Web. 13 Dec 2019.

Vancouver:

Trent AR. Fabrication, Characterization and Cellular Interactions of Keratin Nanomaterial Coatings for Implantable Percutaneous Prosthetics. [Internet] [Doctoral dissertation]. Virginia Tech; 2018. [cited 2019 Dec 13]. Available from: http://hdl.handle.net/10919/94417.

Council of Science Editors:

Trent AR. Fabrication, Characterization and Cellular Interactions of Keratin Nanomaterial Coatings for Implantable Percutaneous Prosthetics. [Doctoral Dissertation]. Virginia Tech; 2018. Available from: http://hdl.handle.net/10919/94417

Massey University

22. Kioumars, Amir Hoshang. Wireless data acquisition and monitoring for healthcare services systems : a thesis in the partial fulfillment of the requirement for the Masters of Engineering (Electronics and Computer Systems), Massey University, Palmerston North, New Zealand .

Degree: 2011, Massey University

URL: http://hdl.handle.net/10179/3585

► The aging population brings challenges to healthcare systems. To cope with the high demand on health professionals and services, the feasible solution is to engage… (more)

▼ The aging population brings challenges to healthcare systems. To cope with the high demand on health professionals and services, the feasible solution is to engage modern technologies. Wireless communication, service robots and information technology have become the active research areas for future healthcare systems. In the field of human health, collecting and analysing the real-time data is vital. New facilities and advanced tools give health service providers and their patients more choices to readily access and use health information and collect and store real-time health data. Information technology (IT) has the potential to improve the quality, safety, and efficiency of healthcare. IT allows healthcare providers to collect, store, retrieve and transfer information electronically. Together with modern communication technologies and intelligent systems, patients are able to monitor their own vital health signs from home and communicate the results to their health providers wirelessly. This will increase the ability to address a problem before a patient requires acute care. The ability to remotely monitor vital signs of a patient in real-time using a simple, low-cost and compact device with a minimum training time is highly desirable in a society with an increasing aging population. This research outlines the design and development of a cost effective and reliable wireless sensing device for collecting real-time health vital signs such as human body temperature and heart rate. A software system is also developed to provide two-way communications with the remote sensor device in order to receive and store the collected data by the sensor device in a central database. The literature review led to the use of ATmega micro-controller, ZigBee technology for wireless communication and the development of highly adaptable, flexible and intelligent software written in Microsoft C-Sharp (C#). A unique communication data packet is also developed and implemented to overcome the micro-controller memory limitations, improving the reliability of the communication and increasing the security of data as well as saving power. The system is able to communicate with service robots and host computers via the network of XBees. The proposed hardware device is able to collect the human heart rate and body temperature in real-time. It is light-weight, low-cost, power efficient and maintainable. It can be wrapped around the wrist and carried with the person. It transmits the data when it is needed and stays on sleep mode to save power. The developed software system (T-HBR, stands for temperature-heart beat rate) is capable of receiving the data from the remote device and storing the data to a central database. T-HBR allows health professionals such as general practitioners (GPs), nurses and healthcare providers to be able to collect the real-time data, see the patient‟s history, issue a new prescription and send it to the patient, other GPs or nurses by e-mails or text messages. The software can be a…

Subjects/Keywords: Wireless communication systems; Medical telematics; Remote sensing; Remote sensing device design; Wireless communication device design; Healthcare device design; Medical informatics

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Kioumars, A. H. (2011). Wireless data acquisition and monitoring for healthcare services systems : a thesis in the partial fulfillment of the requirement for the Masters of Engineering (Electronics and Computer Systems), Massey University, Palmerston North, New Zealand . (Thesis). Massey University. Retrieved from http://hdl.handle.net/10179/3585

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Kioumars, Amir Hoshang. “Wireless data acquisition and monitoring for healthcare services systems : a thesis in the partial fulfillment of the requirement for the Masters of Engineering (Electronics and Computer Systems), Massey University, Palmerston North, New Zealand .” 2011. Thesis, Massey University. Accessed December 13, 2019. http://hdl.handle.net/10179/3585.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Kioumars, Amir Hoshang. “Wireless data acquisition and monitoring for healthcare services systems : a thesis in the partial fulfillment of the requirement for the Masters of Engineering (Electronics and Computer Systems), Massey University, Palmerston North, New Zealand .” 2011. Web. 13 Dec 2019.

Vancouver:

Kioumars AH. Wireless data acquisition and monitoring for healthcare services systems : a thesis in the partial fulfillment of the requirement for the Masters of Engineering (Electronics and Computer Systems), Massey University, Palmerston North, New Zealand . [Internet] [Thesis]. Massey University; 2011. [cited 2019 Dec 13]. Available from: http://hdl.handle.net/10179/3585.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Kioumars AH. Wireless data acquisition and monitoring for healthcare services systems : a thesis in the partial fulfillment of the requirement for the Masters of Engineering (Electronics and Computer Systems), Massey University, Palmerston North, New Zealand . [Thesis]. Massey University; 2011. Available from: http://hdl.handle.net/10179/3585

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Loughborough University

23. Grant, Tom. The involvement of users in the design of home use medical devices : challenges and incentives for change.

Degree: PhD, 2014, Loughborough University

URL: https://dspace.lboro.ac.uk/2134/16283 ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.631590

► The prevalence and use of medical devices in the home environment continues to grow in the United Kingdom (UK) and Worldwide. It is recognised that… (more)

▼ The prevalence and use of medical devices in the home environment continues to grow in the United Kingdom (UK) and Worldwide. It is recognised that such devices offer significant benefits to both patients and the National Health Service in the UK. The design of home use medical devices however represents a considerable challenge to designers and manufacturers alike. Developing devices that are usable and understandable by inexperienced, lay or dexterity impaired users requires an understanding across a breadth of disciplines. Previous research in this field has explored these challenges in attempt to offer support for developers of home use medical devices. There have been very few studies however that have explored whether the design community actually need, want or use such guidance, before considering whether this literature is adopted correctly. Through case studies, an online survey and in depth interviews this thesis suggests that industry practitioners are sceptical of the value of design guidance towards user involvement in home use medical device design. Consequently the practitioners in this research make little or no use of the formal design methods and supportive guidance documents available to them. More typically, practitioners in the home use medical device field use their own personal experiences and knowledge from working in the industry to adapt their own approaches to design. This thesis reports that the greatest challenge to involving users in the design of home use medical devices are the internal corporate and traditionally hierarchical barriers between stakeholders within the design process. In contrast to previous research offering support for designers and developers of home use medical devices this thesis calls for a wider change in design practice to facilitate the application of usability principles. As a conclusion to this thesis, recommendations for further research to address these changes in practice are proposed to industry professionals in the medical device industry. This thesis is submitted as part of the requirement for the Degree of Doctor of Philosophy at Loughborough University.

Subjects/Keywords: 610.28; User involvement; Medical device design; Home use medical devices; Usability

Record Details Similar Records Cite « Share

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Grant, T. (2014). The involvement of users in the design of home use medical devices : challenges and incentives for change. (Doctoral Dissertation). Loughborough University. Retrieved from https://dspace.lboro.ac.uk/2134/16283 ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.631590

Chicago Manual of Style (16^th Edition):

Grant, Tom. “The involvement of users in the design of home use medical devices : challenges and incentives for change.” 2014. Doctoral Dissertation, Loughborough University. Accessed December 13, 2019. https://dspace.lboro.ac.uk/2134/16283 ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.631590.

MLA Handbook (7^th Edition):

Grant, Tom. “The involvement of users in the design of home use medical devices : challenges and incentives for change.” 2014. Web. 13 Dec 2019.

Vancouver:

Grant T. The involvement of users in the design of home use medical devices : challenges and incentives for change. [Internet] [Doctoral dissertation]. Loughborough University; 2014. [cited 2019 Dec 13]. Available from: https://dspace.lboro.ac.uk/2134/16283 ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.631590.

Council of Science Editors:

Grant T. The involvement of users in the design of home use medical devices : challenges and incentives for change. [Doctoral Dissertation]. Loughborough University; 2014. Available from: https://dspace.lboro.ac.uk/2134/16283 ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.631590

Harvard University

24. Xu, Shuai. PROMOTING BREAKTHROUGH MEDICAL INNOVATION: INSIGHTS FROM AN ANALYSIS OF RECENT TRANSFORMATIVE DRUGS, BIOLOGICS AND MEDICAL DEVICES.

Degree: Doctor of Medicine, 2014, Harvard University

URL: http://etds.lib.harvard.edu/hms/admin/view/54 ; http://nrs.harvard.edu/urn-3:HUL.InstRepos:12407612

► Given the recent concern from multiple healthcare stakeholders that the pipeline of medical innovation is slowing, this thesis provides insights on how to spur breakthrough… (more)

Subjects/Keywords: medical innovation; FDA; medical technology; drug development; device development

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APA (6^th Edition):

Xu, S. (2014). PROMOTING BREAKTHROUGH MEDICAL INNOVATION: INSIGHTS FROM AN ANALYSIS OF RECENT TRANSFORMATIVE DRUGS, BIOLOGICS AND MEDICAL DEVICES. (Doctoral Dissertation). Harvard University. Retrieved from http://etds.lib.harvard.edu/hms/admin/view/54 ; http://nrs.harvard.edu/urn-3:HUL.InstRepos:12407612

Chicago Manual of Style (16^th Edition):

Xu, Shuai. “PROMOTING BREAKTHROUGH MEDICAL INNOVATION: INSIGHTS FROM AN ANALYSIS OF RECENT TRANSFORMATIVE DRUGS, BIOLOGICS AND MEDICAL DEVICES.” 2014. Doctoral Dissertation, Harvard University. Accessed December 13, 2019. http://etds.lib.harvard.edu/hms/admin/view/54 ; http://nrs.harvard.edu/urn-3:HUL.InstRepos:12407612.

MLA Handbook (7^th Edition):

Xu, Shuai. “PROMOTING BREAKTHROUGH MEDICAL INNOVATION: INSIGHTS FROM AN ANALYSIS OF RECENT TRANSFORMATIVE DRUGS, BIOLOGICS AND MEDICAL DEVICES.” 2014. Web. 13 Dec 2019.

Vancouver:

Xu S. PROMOTING BREAKTHROUGH MEDICAL INNOVATION: INSIGHTS FROM AN ANALYSIS OF RECENT TRANSFORMATIVE DRUGS, BIOLOGICS AND MEDICAL DEVICES. [Internet] [Doctoral dissertation]. Harvard University; 2014. [cited 2019 Dec 13]. Available from: http://etds.lib.harvard.edu/hms/admin/view/54 ; http://nrs.harvard.edu/urn-3:HUL.InstRepos:12407612.

Council of Science Editors:

Xu S. PROMOTING BREAKTHROUGH MEDICAL INNOVATION: INSIGHTS FROM AN ANALYSIS OF RECENT TRANSFORMATIVE DRUGS, BIOLOGICS AND MEDICAL DEVICES. [Doctoral Dissertation]. Harvard University; 2014. Available from: http://etds.lib.harvard.edu/hms/admin/view/54 ; http://nrs.harvard.edu/urn-3:HUL.InstRepos:12407612

Loughborough University

25. Grant, Tom. The involvement of users in the design of home use medical devices : challenges and incentives for change.

Degree: PhD, 2014, Loughborough University

URL: http://hdl.handle.net/2134/16283

► The prevalence and use of medical devices in the home environment continues to grow in the United Kingdom (UK) and Worldwide. It is recognised that… (more)

▼ The prevalence and use of medical devices in the home environment continues to grow in the United Kingdom (UK) and Worldwide. It is recognised that such devices offer significant benefits to both patients and the National Health Service in the UK. The design of home use medical devices however represents a considerable challenge to designers and manufacturers alike. Developing devices that are usable and understandable by inexperienced, lay or dexterity impaired users requires an understanding across a breadth of disciplines. Previous research in this field has explored these challenges in attempt to offer support for developers of home use medical devices. There have been very few studies however that have explored whether the design community actually need, want or use such guidance, before considering whether this literature is adopted correctly. Through case studies, an online survey and in depth interviews this thesis suggests that industry practitioners are sceptical of the value of design guidance towards user involvement in home use medical device design. Consequently the practitioners in this research make little or no use of the formal design methods and supportive guidance documents available to them. More typically, practitioners in the home use medical device field use their own personal experiences and knowledge from working in the industry to adapt their own approaches to design. This thesis reports that the greatest challenge to involving users in the design of home use medical devices are the internal corporate and traditionally hierarchical barriers between stakeholders within the design process. In contrast to previous research offering support for designers and developers of home use medical devices this thesis calls for a wider change in design practice to facilitate the application of usability principles. As a conclusion to this thesis, recommendations for further research to address these changes in practice are proposed to industry professionals in the medical device industry. This thesis is submitted as part of the requirement for the Degree of Doctor of Philosophy at Loughborough University.

Subjects/Keywords: 610.28; User involvement; Medical device design; Home use medical devices; Usability

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Grant, T. (2014). The involvement of users in the design of home use medical devices : challenges and incentives for change. (Doctoral Dissertation). Loughborough University. Retrieved from http://hdl.handle.net/2134/16283

Chicago Manual of Style (16^th Edition):

Grant, Tom. “The involvement of users in the design of home use medical devices : challenges and incentives for change.” 2014. Doctoral Dissertation, Loughborough University. Accessed December 13, 2019. http://hdl.handle.net/2134/16283.

MLA Handbook (7^th Edition):

Grant, Tom. “The involvement of users in the design of home use medical devices : challenges and incentives for change.” 2014. Web. 13 Dec 2019.

Vancouver:

Grant T. The involvement of users in the design of home use medical devices : challenges and incentives for change. [Internet] [Doctoral dissertation]. Loughborough University; 2014. [cited 2019 Dec 13]. Available from: http://hdl.handle.net/2134/16283.

Council of Science Editors:

Grant T. The involvement of users in the design of home use medical devices : challenges and incentives for change. [Doctoral Dissertation]. Loughborough University; 2014. Available from: http://hdl.handle.net/2134/16283

University of Cincinnati

26. Alley, Krista I. Defining the Industrial Designer's Role in the ISO/IEC 62366 Standard.

Degree: MDES, Design, Architecture, Art and Planning: Design, 2014, University of Cincinnati

URL: http://rave.ohiolink.edu/etdc/view?acc_num=ucin1397235614

► In recent years, the medical device industry has revised its development practices by incorporating the ISO/IEC 62366 (Usability Engineering Process) standard. The standard, purposed to… (more)

Subjects/Keywords: Design; Medical Devices; Medical Device Design; Industrial Design; Usability Engineering; Standardization; ISO IEC 62366

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Alley, K. I. (2014). Defining the Industrial Designer's Role in the ISO/IEC 62366 Standard. (Masters Thesis). University of Cincinnati. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=ucin1397235614

Chicago Manual of Style (16^th Edition):

Alley, Krista I. “Defining the Industrial Designer's Role in the ISO/IEC 62366 Standard.” 2014. Masters Thesis, University of Cincinnati. Accessed December 13, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1397235614.

MLA Handbook (7^th Edition):

Alley, Krista I. “Defining the Industrial Designer's Role in the ISO/IEC 62366 Standard.” 2014. Web. 13 Dec 2019.

Vancouver:

Alley KI. Defining the Industrial Designer's Role in the ISO/IEC 62366 Standard. [Internet] [Masters thesis]. University of Cincinnati; 2014. [cited 2019 Dec 13]. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=ucin1397235614.

Council of Science Editors:

Alley KI. Defining the Industrial Designer's Role in the ISO/IEC 62366 Standard. [Masters Thesis]. University of Cincinnati; 2014. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=ucin1397235614

University of Washington

27. Svanevik, Carl Christian. Testing and Improving the UnTape Medical Device Concept.

Degree: 2018, University of Washington

URL: http://hdl.handle.net/1773/42473

► Strong medical tapes adhere well to the skin and different devices, however require a lot of effort to remove properly and cause medical adhesive related… (more)

Subjects/Keywords: Mechanical Engineering; Medical Device; Medical Tape; UnTape; Wand; Mechanical engineering; Medicine; Mechanical engineering

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APA (6^th Edition):

Svanevik, C. C. (2018). Testing and Improving the UnTape Medical Device Concept. (Thesis). University of Washington. Retrieved from http://hdl.handle.net/1773/42473

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Svanevik, Carl Christian. “Testing and Improving the UnTape Medical Device Concept.” 2018. Thesis, University of Washington. Accessed December 13, 2019. http://hdl.handle.net/1773/42473.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Svanevik, Carl Christian. “Testing and Improving the UnTape Medical Device Concept.” 2018. Web. 13 Dec 2019.

Vancouver:

Svanevik CC. Testing and Improving the UnTape Medical Device Concept. [Internet] [Thesis]. University of Washington; 2018. [cited 2019 Dec 13]. Available from: http://hdl.handle.net/1773/42473.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Svanevik CC. Testing and Improving the UnTape Medical Device Concept. [Thesis]. University of Washington; 2018. Available from: http://hdl.handle.net/1773/42473

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of California – San Francisco

28. Fisher, Joshua. In Vitro Binding Kinetics of ChemoFilter with Cisplatin.

Degree: Biomedical Imaging, 2016, University of California – San Francisco

URL: http://www.escholarship.org/uc/item/6pm2102f

► Introduction: Endovascular chemotherapy treatment allows localized delivery adjacent to the target tumor; allowing an increased dosage and decreased leakage to other areas. It also allows… (more)

▼ Introduction: Endovascular chemotherapy treatment allows localized delivery adjacent to the target tumor; allowing an increased dosage and decreased leakage to other areas. It also allows for the opportunity to filter chemotherapy escaping the target tumor and entering the bloodstream. The ChemoFilter - a temporarily deployable, endovascular device will do just that; reducing systemic toxicity thus reducing adverse side effects from chemotherapy treatment. This will allow further increased dosage, increased tumor suppression, and increased tolerance to treatment. ChemoFilter has successfully filtered the chemotherapeutic Doxorubicin, but had yet to be tested in other chemotherapeutics. This study evaluates binding with new chemotherapeutics: Cisplatin, Carboplatin, and a cocktail comprised of Cisplatin and Doxorubicin. Materials and Methods: ChemoFilter prototypes based on: 1.) Genomic DNA and 2.) Dowex (ion-exchange) resin, were evaluated for their ability to bind chemotherapy in vitro in phosphate-buffered saline (PBS). ChemoFilter was tested free in solution and encapsulated in nylon or polyester mesh packets of various dimensions. Concentrations were quantified using inductively coupled plasma mass spectrometry (IPC-MS), ultraviolet-visible spectrophotometry (UV-Vis), or fluorospectrometry. 11C, 13C, and/or 14C radiolabeling Carboplatin began for in vitro and in vivo ChemoFilter quantification. In vitro quantification can include scintillation and/or gamma counting. In vivo may include Positron Emission Tomography (PET) imaging, Hyperpolarized 13C Magnetic Resonance Imaging (MRI), and/or Magnetic Resonance Spectroscopy (MRS) for real-time visualization. Reactions were verified using High Performance Liquid Chromatography (HPLC) for chemical species identification.Results and Discussion: Results indicate significant and nearly complete, ~99% (p<0.01) clearance of Cisplatin using the DNA ChemoFilter sequestered in Nylon mesh, quantified with gold standard ICP-MS (evidenced at 214 and 265 nm). The Ion-exchange ChemoFilter has significant clearance, within seconds, of both Doxorubicin and Cisplatin mixed in a cocktail solution. However, it appears some Cisplatin is binding to the Nylon Mesh itself. Size, shape, and material of the mesh have been optimized. A potential mechanism for 11C, 13C, or 14C radiolabeling of Carboplatin has been developed and early results have been successful. ChemoFilter works much more efficiently when sequestered in nylon packets of specific geometries. Significant improvements have been made to ChemoFilter, moving the device closer to clinical trials.

Subjects/Keywords: Medical imaging; Medicine; Biochemistry; cancer; ChemoFilter; chemotherapy; Cisplatin; interventional radiology; medical device

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Fisher, J. (2016). In Vitro Binding Kinetics of ChemoFilter with Cisplatin. (Thesis). University of California – San Francisco. Retrieved from http://www.escholarship.org/uc/item/6pm2102f

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Fisher, Joshua. “In Vitro Binding Kinetics of ChemoFilter with Cisplatin.” 2016. Thesis, University of California – San Francisco. Accessed December 13, 2019. http://www.escholarship.org/uc/item/6pm2102f.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Fisher, Joshua. “In Vitro Binding Kinetics of ChemoFilter with Cisplatin.” 2016. Web. 13 Dec 2019.

Vancouver:

Fisher J. In Vitro Binding Kinetics of ChemoFilter with Cisplatin. [Internet] [Thesis]. University of California – San Francisco; 2016. [cited 2019 Dec 13]. Available from: http://www.escholarship.org/uc/item/6pm2102f.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Fisher J. In Vitro Binding Kinetics of ChemoFilter with Cisplatin. [Thesis]. University of California – San Francisco; 2016. Available from: http://www.escholarship.org/uc/item/6pm2102f

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Brunel University

29. Stead, Thomas. An investigation into the application of design processes to novel self-use molecular diagnostic devices for sexually transmitted infections.

Degree: PhD, 2017, Brunel University

URL: http://bura.brunel.ac.uk/handle/2438/15197 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.764807

► The purpose of this research was to investigate the application of design processes to the development of novel self-use molecular diagnostic devices for sexually transmitted… (more)

Subjects/Keywords: Medical device design; Medical design process; Design for diagnostic devices; System thinking; Design thinking

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Stead, T. (2017). An investigation into the application of design processes to novel self-use molecular diagnostic devices for sexually transmitted infections. (Doctoral Dissertation). Brunel University. Retrieved from http://bura.brunel.ac.uk/handle/2438/15197 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.764807

Chicago Manual of Style (16^th Edition):

Stead, Thomas. “An investigation into the application of design processes to novel self-use molecular diagnostic devices for sexually transmitted infections.” 2017. Doctoral Dissertation, Brunel University. Accessed December 13, 2019. http://bura.brunel.ac.uk/handle/2438/15197 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.764807.

MLA Handbook (7^th Edition):

Stead, Thomas. “An investigation into the application of design processes to novel self-use molecular diagnostic devices for sexually transmitted infections.” 2017. Web. 13 Dec 2019.

Vancouver:

Stead T. An investigation into the application of design processes to novel self-use molecular diagnostic devices for sexually transmitted infections. [Internet] [Doctoral dissertation]. Brunel University; 2017. [cited 2019 Dec 13]. Available from: http://bura.brunel.ac.uk/handle/2438/15197 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.764807.

Council of Science Editors:

Stead T. An investigation into the application of design processes to novel self-use molecular diagnostic devices for sexually transmitted infections. [Doctoral Dissertation]. Brunel University; 2017. Available from: http://bura.brunel.ac.uk/handle/2438/15197 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.764807

University of Limerick

30. Wallace, Nicole. Examining the perspectives of patients, clinicians and product designers on the design of a tool for measurement and rehabilitation of swallowing.

Degree: 2015, University of Limerick

URL: http://hdl.handle.net/10344/4963

►

non-peer-reviewed

Background: Tools available for dysphagia rehabilitation are limited in number and type. OroPress is a clinic-ready prototype tongue pressure measurement tool which may be… (more)

Subjects/Keywords: focus groups; dysphagia; head and neck cancer; rehabilitation; medical device design

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Wallace, N. (2015). Examining the perspectives of patients, clinicians and product designers on the design of a tool for measurement and rehabilitation of swallowing. (Thesis). University of Limerick. Retrieved from http://hdl.handle.net/10344/4963

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Wallace, Nicole. “Examining the perspectives of patients, clinicians and product designers on the design of a tool for measurement and rehabilitation of swallowing.” 2015. Thesis, University of Limerick. Accessed December 13, 2019. http://hdl.handle.net/10344/4963.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Wallace, Nicole. “Examining the perspectives of patients, clinicians and product designers on the design of a tool for measurement and rehabilitation of swallowing.” 2015. Web. 13 Dec 2019.

Vancouver:

Wallace N. Examining the perspectives of patients, clinicians and product designers on the design of a tool for measurement and rehabilitation of swallowing. [Internet] [Thesis]. University of Limerick; 2015. [cited 2019 Dec 13]. Available from: http://hdl.handle.net/10344/4963.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Wallace N. Examining the perspectives of patients, clinicians and product designers on the design of a tool for measurement and rehabilitation of swallowing. [Thesis]. University of Limerick; 2015. Available from: http://hdl.handle.net/10344/4963

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

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Open Access Theses and Dissertations