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University of Toronto
1.
Chan, David.
The “Gist” of Early Visual Processing.
Degree: 2012, University of Toronto
URL: http://hdl.handle.net/1807/33362
► Visual information is processed by two separate visual pathways. One is the magnocellular visual pathway (M-pathway), which carries high temporal frequency information but low spatial…
(more)
▼ Visual information is processed by two separate visual pathways. One is the magnocellular visual pathway (M-pathway), which carries high temporal frequency information but low spatial frequency information. The other is the parvocellular visual pathway (P-pathway), which carries low temporal information but high spatial information. Kveraga and colleagues (2007) presented participants with high and low spatial frequency images and found that participants made faster and more accurate categorization responses to the low spatial frequency images. They hypothesized this was due to low spatial frequency “gist” information being rapidly carried by the M-pathway. Using diffuse light and hand posture manipulations, we replicated the advantage for low spatial frequency (LSF) images in both experiments, and also found a larger advantage for LSF information when biasing the M-pathway (using hand posture). We were unable to inhibit the M-pathway using red diffuse light. Thus, it does appear “gist” processing is uniquely carried by the M-pathway.
MAST
Advisors/Committee Members: Pratt, Jay, Psychology.
Subjects/Keywords: Cognition; Vision; magnocellular; parvocellular; 0633
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APA (6th Edition):
Chan, D. (2012). The “Gist” of Early Visual Processing. (Masters Thesis). University of Toronto. Retrieved from http://hdl.handle.net/1807/33362
Chicago Manual of Style (16th Edition):
Chan, David. “The “Gist” of Early Visual Processing.” 2012. Masters Thesis, University of Toronto. Accessed March 01, 2021.
http://hdl.handle.net/1807/33362.
MLA Handbook (7th Edition):
Chan, David. “The “Gist” of Early Visual Processing.” 2012. Web. 01 Mar 2021.
Vancouver:
Chan D. The “Gist” of Early Visual Processing. [Internet] [Masters thesis]. University of Toronto; 2012. [cited 2021 Mar 01].
Available from: http://hdl.handle.net/1807/33362.
Council of Science Editors:
Chan D. The “Gist” of Early Visual Processing. [Masters Thesis]. University of Toronto; 2012. Available from: http://hdl.handle.net/1807/33362
2.
Zisman, Celia.
Magnocellular Impairments in Autism Spectrum Disorders as Assesses by Visual Evoked Potentials.
Degree: 2013, University of Nevada – Reno
URL: http://hdl.handle.net/11714/3071
► Motion perception in Autism Spectrum Disorders (ASD) has become a salient topic in the past few years. Several studies have found links between abnormal motion…
(more)
▼ Motion perception in Autism Spectrum Disorders (ASD) has become a salient topic in the past few years. Several studies have found links between abnormal motion processing and symptomatology in ASDs, suggesting that impaired
magnocellular function may underlie some of the various symptoms and outcomes in individuals with ASD. The following study explored achromatic motion perception processing differences in high-functioning adolescents with Autism Spectrum Disorder (ASD). Previous studies have shown abnormalities in the way that individuals with ASD perceive motion, including biological and coherent motion, but few studies have examined pattern-reversal and expanding and contracting motion. Abnormalities can have implications for ASD symptomatology, including emotional/facial expression processing, and difficulty with integration of visual information with other cognitive information, such as social cues and communication systems. Two motion stimuli, a reversing checkerboard and an expanding and contracting dartboard, were displayed for ASD male participants and male and female neurotypical control groups. Visual-evoked potentials (VEPs) were used to examine differences in time-to-peak amplitude, area amplitude, and latency of the VEP in participants. Results showed that there are
magnocellular impairments in ASD. There were several main effects for check size and contrast and significant 3-way interactions for contrast, check size and diagnosis in P1 area amplitude and N1 fractional area latency for all three groups, and P1 peak amplitude for ASD males and neurotypical males. Results imply that contrast and size in environment have an effect on how individuals with ASD process visual stimuli, which can explain some of their symptomatology and difficulty with other forms of processing that follow the
magnocellular process. Future research can focus on successful interventions that aim to correct these deficits in visual-motion processing and as a result, help treat the individuals with innovative therapies that improve quality of life. These results can also have implications for early diagnosis and treatment, and possibly prevention.
Advisors/Committee Members: Hutsler, Jeffrey J. (advisor), Crognale, Michael (committee member), Cook, Daniel M (committee member), Hutsler, Jeffrey J (committee member).
Subjects/Keywords: Autism; Electrophysiology; Magnocellular; VEP
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
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APA (6th Edition):
Zisman, C. (2013). Magnocellular Impairments in Autism Spectrum Disorders as Assesses by Visual Evoked Potentials. (Thesis). University of Nevada – Reno. Retrieved from http://hdl.handle.net/11714/3071
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Zisman, Celia. “Magnocellular Impairments in Autism Spectrum Disorders as Assesses by Visual Evoked Potentials.” 2013. Thesis, University of Nevada – Reno. Accessed March 01, 2021.
http://hdl.handle.net/11714/3071.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Zisman, Celia. “Magnocellular Impairments in Autism Spectrum Disorders as Assesses by Visual Evoked Potentials.” 2013. Web. 01 Mar 2021.
Vancouver:
Zisman C. Magnocellular Impairments in Autism Spectrum Disorders as Assesses by Visual Evoked Potentials. [Internet] [Thesis]. University of Nevada – Reno; 2013. [cited 2021 Mar 01].
Available from: http://hdl.handle.net/11714/3071.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Zisman C. Magnocellular Impairments in Autism Spectrum Disorders as Assesses by Visual Evoked Potentials. [Thesis]. University of Nevada – Reno; 2013. Available from: http://hdl.handle.net/11714/3071
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Otago
3.
Han, Su Young.
Plasticity in vasopressin magnocellular neurosecretory cell activity in hypertension
.
Degree: 2013, University of Otago
URL: http://hdl.handle.net/10523/4392
► While the initial event that triggers essential hypertension is unknown, circulating vasopressin levels are paradoxically elevated in some patients with established hypertension. Vasopressin secretion is…
(more)
▼ While the initial event that triggers essential hypertension is unknown, circulating vasopressin levels are paradoxically elevated in some patients with established hypertension. Vasopressin secretion is determined by action potential discharge of vasopressin
magnocellular neurosecretory cells (MNCs). Hence, vasopressin MNC activity might be paradoxically increased in hypertension. To determine whether increased vasopressin MNC activity might contribute to the development of hypertension, I recorded the activity of vasopressin MNCs during the induction of hypertension in genetically modified rats that have the transgene, Cyp1a1-Ren2 (comprised of the mouse renin, Ren-2, gene fused to the cytochrome P450, Cyp1a1, promoter), inserted in the Y-Chromosome of Fischer 344 (F344) rats. Activation of the Cyp1a1 promoter by dietary administration of indole-3-carbinol (I3C) results in a fixed level of Ren-2 gene expression and leads to the development of angiotensin II (Ang II)-dependent hypertension.
Telemetric recording of arterial blood pressure (ABP) showed the development of hypertension in Cyp1a1-Ren2 rats in a dose- and time-dependent manner: on 0.15% (w/w) I3C mild hypertension developed over thirteen days [mean ABP (MABP): 120 ± 6 mmHg)]; on 0.225% I3C moderate hypertension developed over seven days (MABP: 140 ± 6 mmHg); and on 0.3% I3C severe hypertension developed over five days (MABP: 161 ± 4 mmHg). Only Cyp1a1-Ren2 rats developed hypertension, only upon the consumption of I3C-containing diet.
To investigate whether the activity of vasopressin MNCs change in hypertension, extracellular single-unit recordings of supraoptic nucleus (SON) vasopressin MNCs were made from urethane-anaesthetized F344 rats fed ordinary diet and from Cyp1a1a-Ren2 rats fed ordinary diet (CYP rats) or 0.225% I3C (HD7 rats) for seven days. The basal firing rate of vasopressin MNCs in HD7 rats was higher (8.8 ± 0.8 spikes s-1; F = 5.27, P = 0.007, one-way ANOVA; n = 23 cells from 9 rats) than in F344 rats (6.3 ± 0.7 spikes s-1; P = 0.03, Bonferroni’s post-hoc test; n = 30 cells 11 rats) and CYP rats (6.1 ± 0.5 spikes s-1; P = 0.01, Bonferroni’s post-hoc test; n = 22 cells 14 rats). Stimulation of afferent baroreceptor input by intravenous (i.v.) injection of 2.5 µg kg-1 of the α1 aderenoreceptor agonist, phenylephrine (PE), induced a transient rise in MABP from 74 ± 3 to 119 ± 4 mmHg in F344 rats (n = 8 rats), and from 70 ± 3 to 113 ± 3 mmHg in CYP rats (n = 9 rats), which was accompanied by an inhibition of vasopressin MNC firing rate by 55.9 ± 8.4% (n = 16 cells) and 52.4 ± 8.8% (n = 15 cells), respectively. In HD7 rats, PE induced a similar elevation of MABP (77 ± 4 to 124 ± 3 mmHg; n = 7 rats) to that seen in F344 and CYP rats (interaction: F = 0.53, P = 0.59, two-way RM ANOVA), but did not inhibit vasopressin MNC firing rate (increased by 14.8 ± 33.7 %; n = 13 cells; F = 4.92, P = 0.01, one way ANOVA).
To investigate whether the plastic changes occurred in vasopressin MNCs are mediated by angiotensin II (Ang II)-sensitive afferent input…
Advisors/Committee Members: Brown, Colin H (advisor).
Subjects/Keywords: hypertension;
vasopressin;
magnocellular;
hypothalamus;
SON;
MNC
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Han, S. Y. (2013). Plasticity in vasopressin magnocellular neurosecretory cell activity in hypertension
. (Doctoral Dissertation). University of Otago. Retrieved from http://hdl.handle.net/10523/4392
Chicago Manual of Style (16th Edition):
Han, Su Young. “Plasticity in vasopressin magnocellular neurosecretory cell activity in hypertension
.” 2013. Doctoral Dissertation, University of Otago. Accessed March 01, 2021.
http://hdl.handle.net/10523/4392.
MLA Handbook (7th Edition):
Han, Su Young. “Plasticity in vasopressin magnocellular neurosecretory cell activity in hypertension
.” 2013. Web. 01 Mar 2021.
Vancouver:
Han SY. Plasticity in vasopressin magnocellular neurosecretory cell activity in hypertension
. [Internet] [Doctoral dissertation]. University of Otago; 2013. [cited 2021 Mar 01].
Available from: http://hdl.handle.net/10523/4392.
Council of Science Editors:
Han SY. Plasticity in vasopressin magnocellular neurosecretory cell activity in hypertension
. [Doctoral Dissertation]. University of Otago; 2013. Available from: http://hdl.handle.net/10523/4392

University of Georgia
4.
Skalicky, Aaron Emil.
The relationship between early visual processing and reading ability : investigation of temporal processing in adults and children.
Degree: 2014, University of Georgia
URL: http://hdl.handle.net/10724/29430
► Evidence from psychophysical, physiological and neuroimaging studies suggests that functioning of the magnocellular pathway, which is specialized for processing moving stimuli at low-contrast conditions, correlates…
(more)
▼ Evidence from psychophysical, physiological and neuroimaging studies suggests that functioning of the magnocellular pathway, which is specialized for processing moving stimuli at low-contrast conditions, correlates with reading performance.
Nevertheless, the magnocellular-deficit hypothesis remains somewhat controversial. Some researchers continue to publish conflicting evidence, although differences in subject selection criteria and visual stimuli may contribute to discrepant findings.
Recent functional neuroimaging studies provide compelling evidence that, in response to moving stimuli at low-contrast conditions, dyslexics evidence a characteristic pattern of physiological under-activation in V5 (MT), an extrastriate area predominated
by magnocellular input. Results from this psychophysical study support the hypothesized relationship between magnocellular function and reading ability for adults, but not for children and adolescents. The psychophysical stimuli used in this study might
help to advance neuroimaging of early visual correlates with adults. Conversely, these stimuli offer questionable utility to the development of screening instruments that might one day predict developmental dyslexia with young children.
Subjects/Keywords: Early Visual Processing; Magnocellular Pathway; Developmental Dyslexia
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APA ·
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APA (6th Edition):
Skalicky, A. E. (2014). The relationship between early visual processing and reading ability : investigation of temporal processing in adults and children. (Thesis). University of Georgia. Retrieved from http://hdl.handle.net/10724/29430
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Skalicky, Aaron Emil. “The relationship between early visual processing and reading ability : investigation of temporal processing in adults and children.” 2014. Thesis, University of Georgia. Accessed March 01, 2021.
http://hdl.handle.net/10724/29430.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Skalicky, Aaron Emil. “The relationship between early visual processing and reading ability : investigation of temporal processing in adults and children.” 2014. Web. 01 Mar 2021.
Vancouver:
Skalicky AE. The relationship between early visual processing and reading ability : investigation of temporal processing in adults and children. [Internet] [Thesis]. University of Georgia; 2014. [cited 2021 Mar 01].
Available from: http://hdl.handle.net/10724/29430.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Skalicky AE. The relationship between early visual processing and reading ability : investigation of temporal processing in adults and children. [Thesis]. University of Georgia; 2014. Available from: http://hdl.handle.net/10724/29430
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Otago
5.
Seymour, Alexander James.
Regulation of Oxytocin Magnocellular Neurosecretory Cells by Kisspeptin in Late Pregnancy
.
Degree: University of Otago
URL: http://hdl.handle.net/10523/6526
► Oxytocin magnocellular neurosecretory cells (MNCs) are located in the supraoptic nucleus (SON) and paraventricular nucleus of the hypothalamus. MNC activity during parturition results in secretion…
(more)
▼ Oxytocin
magnocellular neurosecretory cells (MNCs) are located in the supraoptic nucleus (SON) and paraventricular nucleus of the hypothalamus. MNC activity during parturition results in secretion of oxytocin into the bloodstream to facilitate uterine contraction, which aids delivery of the offspring. The regulation of oxytocin MNCs during late pregnancy and parturition is not completely understood. Kisspeptin is a peptide that has become widely recognised as a positive regulator of gonadotropin releasing hormone neurons and is essential for normal fertility. Previous work in the Brown lab has shown that kisspeptin also excites oxytocin MNCs from late-pregnant rats in vivo, but does not affect oxytocin MNCs from virgin rats. Furthermore, the expression of kisspeptin in fibres of the perinuclear zone (PNZ) of the SON is higher in late-pregnant rats compared to virgin rats. These results suggest that kisspeptin might be involved in excitation of oxytocin MNCs in late pregnancy to release oxytocin during parturition. The aim of this thesis is to further elucidate the mechanisms regarding the activation of oxytocin MNCs in late-pregnant rats.
Firstly, I confirmed earlier results by showing that kisspeptin fibre density in the PNZ was significantly higher in late-pregnant rats compared to virgin rats. Furthermore, I showed that kisspeptin expression in cell bodies was significantly higher in the rostral periventricular region of the third ventricle but was lower in the arcuate nucleus. To identify the origin of PNZ kisspeptin fibres, I conducted retrograde tracing and showed that only kisspeptin neurons from the periventricular nucleus co-expressed retrograde tracer, indicating that this is the region from which the neurons project.
Next, I performed patch clamp electrophysiology to determine whether kisspeptin excitation of oxytocin MNCs in vivo is evident in brain slices and whether the membrane properties of oxytocin MNCs are affected by kisspeptin. Using cell-attached recordings, I showed that kisspeptin did not affect action current frequency of MNCs in slices from virgin or late-pregnant rats. Because kisspeptin might affect membrane currents that are not strong enough to increase activity in the slice, I used whole-cell recordings of SON MNCs to measure postsynaptic currents. Kisspeptin did not affect excitatory or inhibitory postsynaptic current frequency or amplitude, suggesting that kisspeptin does not affect MNCs indirectly through modulation of glutamatergic or GABAergic inputs. Furthermore, kisspeptin did not affect MNC holding currents, indicating that kisspeptin does not act directly on MNCs. To determine whether central kisspeptin increased oxytocin MNC activation, I conducted immunohistochemistry for the marker of neuronal activation, Fos protein. Kisspeptin did not increase Fos expression in oxytocin MNCs in virgin or pregnant rats. Furthermore, central injection of antagonists to the kisspeptin receptor (Kiss1R) or neuropeptide FF receptor (NPFFR), receptors through which kisspeptin has been shown to…
Advisors/Committee Members: Brown, Colin H (advisor).
Subjects/Keywords: Oxytocin;
kisspeptin;
pregnancy;
magnocellular;
parturition
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Seymour, A. J. (n.d.). Regulation of Oxytocin Magnocellular Neurosecretory Cells by Kisspeptin in Late Pregnancy
. (Doctoral Dissertation). University of Otago. Retrieved from http://hdl.handle.net/10523/6526
Note: this citation may be lacking information needed for this citation format:
No year of publication.
Chicago Manual of Style (16th Edition):
Seymour, Alexander James. “Regulation of Oxytocin Magnocellular Neurosecretory Cells by Kisspeptin in Late Pregnancy
.” Doctoral Dissertation, University of Otago. Accessed March 01, 2021.
http://hdl.handle.net/10523/6526.
Note: this citation may be lacking information needed for this citation format:
No year of publication.
MLA Handbook (7th Edition):
Seymour, Alexander James. “Regulation of Oxytocin Magnocellular Neurosecretory Cells by Kisspeptin in Late Pregnancy
.” Web. 01 Mar 2021.
Note: this citation may be lacking information needed for this citation format:
No year of publication.
Vancouver:
Seymour AJ. Regulation of Oxytocin Magnocellular Neurosecretory Cells by Kisspeptin in Late Pregnancy
. [Internet] [Doctoral dissertation]. University of Otago; [cited 2021 Mar 01].
Available from: http://hdl.handle.net/10523/6526.
Note: this citation may be lacking information needed for this citation format:
No year of publication.
Council of Science Editors:
Seymour AJ. Regulation of Oxytocin Magnocellular Neurosecretory Cells by Kisspeptin in Late Pregnancy
. [Doctoral Dissertation]. University of Otago; Available from: http://hdl.handle.net/10523/6526
Note: this citation may be lacking information needed for this citation format:
No year of publication.

University of California – Berkeley
6.
Denison, Rachel.
Parallel and Competitive Processes in Low-Level Vision and Their Impact on Awareness.
Degree: Neuroscience, 2013, University of California – Berkeley
URL: http://www.escholarship.org/uc/item/5dm049zd
► Perception consists of the brain's single best interpretation of the sensory world at a given moment in time. Multiple channels of visual input - be…
(more)
▼ Perception consists of the brain's single best interpretation of the sensory world at a given moment in time. Multiple channels of visual input - be they from the two eyes or from the many parallel visual pathways that originate as early as the retina - must be reconciled to arrive at a unified percept. The fact that this must occur in roughly real time as the visual scene changes poses special challenges and constraints. I investigated two classes of visual processes relevant for the perception of time-varying visual stimuli: prediction, with a probable neural substrate in early visual cortical areas, and parallel processing in the magnocellular (M) and parvocellular (P) pathways. In Chapters 2 and 3, I asked how prediction and parallel pathways, respectively, contribute to perceptual selection using dynamic binocular rivalry stimuli. In binocular rivalry, incompatible images presented to the two eyes result in just one of the images being selected for awareness at any given time. This bistability makes rivalry a useful tool for the study of perceptual selection. In Chapter 2, we found that predictive context in the form of an unambiguous rotating grating biased perceptual selection during subsequent rivalry towards the expected next grating in the rotation sequence, compared to an orthogonal grating. This provided evidence that a prediction-like process influences perceptual selection during rivalry between gratings, which other work has shown is likely resolved at early stages of visual processing. In Chapter 3, we studied spatial, temporal, luminance, and chromatic factors influencing perceptual selection during interocular switch rivalry. In this type of rivalry, flickering orthogonal gratings are periodically exchanged between the two eyes, resulting in either the perception of a fast, regular alternation between orthogonally oriented gratings (similar to the display presented to a single eye) or a slow, irregular alternation, a percept that requires integration across the two eyes over time. We found that stimuli biased toward the M pathway increased the prevalence of fast, regular alternations, while stimuli biased toward the P pathway increased the prevalence of slow, irregular alternations. This finding suggested that the M and P pathways can make distinct contributions to perception during binocular rivalry and led us to propose a new framework for understanding perceptual selection during interocular switch rivalry.Physiological measurement of activity in the M and P pathways can lead to greater understanding of how these pathways contribute to perceptual experience, but methods for measuring functional signals from the M and P pathways of humans have been lacking. Therefore, in Chapter 4, we developed a procedure for functionally mapping the M and P subdivisions of human LGN, the site where these pathways are most clearly segregated, using functional magnetic resonance imaging (fMRI). We observed a gradient of more M-like to more P-like responses across the LGN. Importantly, this gradient had a spatial…
Subjects/Keywords: Neurosciences; Psychology; binocular rivalry; fMRI; LGN; magnocellular; parvocellular; visual perception
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Denison, R. (2013). Parallel and Competitive Processes in Low-Level Vision and Their Impact on Awareness. (Thesis). University of California – Berkeley. Retrieved from http://www.escholarship.org/uc/item/5dm049zd
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Denison, Rachel. “Parallel and Competitive Processes in Low-Level Vision and Their Impact on Awareness.” 2013. Thesis, University of California – Berkeley. Accessed March 01, 2021.
http://www.escholarship.org/uc/item/5dm049zd.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Denison, Rachel. “Parallel and Competitive Processes in Low-Level Vision and Their Impact on Awareness.” 2013. Web. 01 Mar 2021.
Vancouver:
Denison R. Parallel and Competitive Processes in Low-Level Vision and Their Impact on Awareness. [Internet] [Thesis]. University of California – Berkeley; 2013. [cited 2021 Mar 01].
Available from: http://www.escholarship.org/uc/item/5dm049zd.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Denison R. Parallel and Competitive Processes in Low-Level Vision and Their Impact on Awareness. [Thesis]. University of California – Berkeley; 2013. Available from: http://www.escholarship.org/uc/item/5dm049zd
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Georgia
7.
Siddiqui, Aisha Patrice.
Effect of spatial frequency adaptation on location-based inhibition of return as a function of target spatial frequency.
Degree: 2014, University of Georgia
URL: http://hdl.handle.net/10724/26154
► The current study used an inhibition of return (IOR) paradigm to investigate the relationship between spatial attention and the magnocellular (M) and parvocellular (P) pathways.…
(more)
▼ The current study used an inhibition of return (IOR) paradigm to investigate the relationship between spatial attention and the magnocellular (M) and parvocellular (P) pathways. By selectively adapting participants to a particular spatial
frequency (1 cpd or 12 cpd), we expected to find differences in IOR values depending on how adaptation influenced visual pathway activity. Simple reaction times (RTs) to target onset were relatively equal across adaptation conditions, with RTs to 12 cpd
targets longer than RTs to 1 cpd targets. Target spatial frequency differences in IOR were not found. However, overall IOR was greater in the 1 cpd, relative to the 12 cpd adaptation condition and the control condition. These findings suggest adapting
the M-pathway using a low spatial frequency affected IOR more than adapting the P-pathway using a high spatial frequency.
Subjects/Keywords: spatial frequency adaptation; inhibition of return; covert attention; magnocellular & parvocellular pathways
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
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APA (6th Edition):
Siddiqui, A. P. (2014). Effect of spatial frequency adaptation on location-based inhibition of return as a function of target spatial frequency. (Thesis). University of Georgia. Retrieved from http://hdl.handle.net/10724/26154
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Siddiqui, Aisha Patrice. “Effect of spatial frequency adaptation on location-based inhibition of return as a function of target spatial frequency.” 2014. Thesis, University of Georgia. Accessed March 01, 2021.
http://hdl.handle.net/10724/26154.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Siddiqui, Aisha Patrice. “Effect of spatial frequency adaptation on location-based inhibition of return as a function of target spatial frequency.” 2014. Web. 01 Mar 2021.
Vancouver:
Siddiqui AP. Effect of spatial frequency adaptation on location-based inhibition of return as a function of target spatial frequency. [Internet] [Thesis]. University of Georgia; 2014. [cited 2021 Mar 01].
Available from: http://hdl.handle.net/10724/26154.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Siddiqui AP. Effect of spatial frequency adaptation on location-based inhibition of return as a function of target spatial frequency. [Thesis]. University of Georgia; 2014. Available from: http://hdl.handle.net/10724/26154
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
8.
Lang, Jenny Louise.
Asymmetry in the Magnocellular and Parvocellular Pathways.
Degree: PhD, 2014, University of New Hampshire
URL: https://scholars.unh.edu/dissertation/2173
► Why humans are less sensitive to increment than decrement contrast remains unknown. One hypothesis is that the psychophysical asymmetry in increment and decrement thresholds results…
(more)
▼ Why humans are less sensitive to increment than decrement contrast remains unknown. One hypothesis is that the psychophysical asymmetry in increment and decrement thresholds results from an asymmetry in respective ON and OFF cell contrast gains. Contrast gain also differs, however, by the visual pathway within which the ON and OFF cells travel. Cells show greater contrast gain in the
magnocellular (M) than parvocellular (P) pathway. Therefore, the asymmetry in increment and decrement thresholds may also differ by visual pathway. My first three experiments established that observers were more sensitive to decrement than increment contrast in both pathways, in monocular as well as dichoptic conditions. Contrast gain model analyses revealed greater asymmetry in increment and decrement contrast gains only in the P pathway. Lower decrement relative to increment contrast gains resulted in progressively lower decrement than increment contrast discrimination thresholds. Also found was that only decrement binocular summation increased as stimulus contrast increased. Therefore, the two remaining experiments assessed P pathway binocular summation of disparate increment or decrement contrast. An interocular contrast disparity in stimulus contrast generated a strong nonlinear weighting towards the eye with greater delta pedestal contrast during decrement binocular summation and reduced contrast discrimination threshold. Manipulation of two mediating contrast gain normalization processes reduced the disparity and increased the threshold. Combined, the five experiments provide psychophysical evidence that differences in increment and decrement contrast gain normalization underlie the asymmetries in increment and decrement contrast discrimination threshold and binocular summation.
Advisors/Committee Members: William W Stine, Robert C Drugan, Robert S Ross.
Subjects/Keywords: asymmetry; contrast; magnocellular; normalization; parvocellular; vision; Experimental psychology; Psychology
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
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APA (6th Edition):
Lang, J. L. (2014). Asymmetry in the Magnocellular and Parvocellular Pathways. (Doctoral Dissertation). University of New Hampshire. Retrieved from https://scholars.unh.edu/dissertation/2173
Chicago Manual of Style (16th Edition):
Lang, Jenny Louise. “Asymmetry in the Magnocellular and Parvocellular Pathways.” 2014. Doctoral Dissertation, University of New Hampshire. Accessed March 01, 2021.
https://scholars.unh.edu/dissertation/2173.
MLA Handbook (7th Edition):
Lang, Jenny Louise. “Asymmetry in the Magnocellular and Parvocellular Pathways.” 2014. Web. 01 Mar 2021.
Vancouver:
Lang JL. Asymmetry in the Magnocellular and Parvocellular Pathways. [Internet] [Doctoral dissertation]. University of New Hampshire; 2014. [cited 2021 Mar 01].
Available from: https://scholars.unh.edu/dissertation/2173.
Council of Science Editors:
Lang JL. Asymmetry in the Magnocellular and Parvocellular Pathways. [Doctoral Dissertation]. University of New Hampshire; 2014. Available from: https://scholars.unh.edu/dissertation/2173
9.
Bordaberry, Pierre.
Fonctionnement et dysfonctionnement du système visuel : une dissociation entre systèmes parvocellulaire et magnocellulaire chez l’adulte jeune et âgé et rôle de la dopamine : Function and dysfunction of the visual system : a dissociation between parvocellular and magnocellular systems in the young adult and aging and the role of dopamine.
Degree: Docteur es, Psychologie, 2011, Université de Bordeaux Segalen
URL: http://www.theses.fr/2011BOR21816
► L'objectif de cette thèse était l'investigation du fonctionnement et des dysfonctionnements des deux systèmes visuels principaux (magnocellulaire et parvocellulaire). Une synthèse théorique sur la dissociation…
(more)
▼ L'objectif de cette thèse était l'investigation du fonctionnement et des dysfonctionnements des deux systèmes visuels principaux (magnocellulaire et parvocellulaire). Une synthèse théorique sur la dissociation de ces deux systèmes et une revue sur les procédures expérimentales permettant de les dissocier constituaient la première partie de cette thèse. Ensuite, des arguments neuropsychologiques concernant le vieillissement normal et pathologique du système visuel ont été synthétisés et différents résultats de la littérature ont été analysés pour étayer cette dissociation. La quinzaine d’expériences réalisées a mis en évidence deux résultats principaux. Il y a un déficit massif du système parvocellulaire dans le vieillissement normal dès les étapes précoces du traitement et qui perdure aux étapes plus tardives, ainsi qu’un déficit magnocellulaire sous certaines conditions seulement. L'étude des dysfonctionnements visuels dans les pathologies à syndromes extrapyramidaux a montré que ces patients présentaient un déficit spécifiquement magnocellulaire en lien avec la dénervation dopaminergique dans le système central, objectivée à l’aide d’une technique de scintigraphie cérébrale.
The objective was to investigate the normal functioning and the impairment of the two main visual systems, the parvocellular and the magnocellular systems. A theoretical review on the two systems and on the experimental procedures that have been used to dissociate them is proposed in the first chapter. In a second part, a synthesis of the neuropsychological studies focusing on the normal aging of the visual system and on the visual deficits found in various pathologies, that support the parvocellular / magnocellular dissociation is presented. The experimental chapter comprised about fifteen experiments and showed two main results: 1/ a major low-level parvocellular impairment with normal aging that was not compensated at the later stages, and a slighter magnocellular impairment under certain conditions: 2/ a specific deterioration of the magnocellular system in extrapyramidal patients, correlated with dopamine denervation in two structures of the central system.
Advisors/Committee Members: Cousson-Gélie, Florence (thesis director), Delord, Sandrine (thesis director).
Subjects/Keywords: Vision; Magnocellulaire; Parvocellulaire; Dopamine; Vieillissement; Vision; Parvocellular; Magnocellular; Dopamine; Aging
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Bordaberry, P. (2011). Fonctionnement et dysfonctionnement du système visuel : une dissociation entre systèmes parvocellulaire et magnocellulaire chez l’adulte jeune et âgé et rôle de la dopamine : Function and dysfunction of the visual system : a dissociation between parvocellular and magnocellular systems in the young adult and aging and the role of dopamine. (Doctoral Dissertation). Université de Bordeaux Segalen. Retrieved from http://www.theses.fr/2011BOR21816
Chicago Manual of Style (16th Edition):
Bordaberry, Pierre. “Fonctionnement et dysfonctionnement du système visuel : une dissociation entre systèmes parvocellulaire et magnocellulaire chez l’adulte jeune et âgé et rôle de la dopamine : Function and dysfunction of the visual system : a dissociation between parvocellular and magnocellular systems in the young adult and aging and the role of dopamine.” 2011. Doctoral Dissertation, Université de Bordeaux Segalen. Accessed March 01, 2021.
http://www.theses.fr/2011BOR21816.
MLA Handbook (7th Edition):
Bordaberry, Pierre. “Fonctionnement et dysfonctionnement du système visuel : une dissociation entre systèmes parvocellulaire et magnocellulaire chez l’adulte jeune et âgé et rôle de la dopamine : Function and dysfunction of the visual system : a dissociation between parvocellular and magnocellular systems in the young adult and aging and the role of dopamine.” 2011. Web. 01 Mar 2021.
Vancouver:
Bordaberry P. Fonctionnement et dysfonctionnement du système visuel : une dissociation entre systèmes parvocellulaire et magnocellulaire chez l’adulte jeune et âgé et rôle de la dopamine : Function and dysfunction of the visual system : a dissociation between parvocellular and magnocellular systems in the young adult and aging and the role of dopamine. [Internet] [Doctoral dissertation]. Université de Bordeaux Segalen; 2011. [cited 2021 Mar 01].
Available from: http://www.theses.fr/2011BOR21816.
Council of Science Editors:
Bordaberry P. Fonctionnement et dysfonctionnement du système visuel : une dissociation entre systèmes parvocellulaire et magnocellulaire chez l’adulte jeune et âgé et rôle de la dopamine : Function and dysfunction of the visual system : a dissociation between parvocellular and magnocellular systems in the young adult and aging and the role of dopamine. [Doctoral Dissertation]. Université de Bordeaux Segalen; 2011. Available from: http://www.theses.fr/2011BOR21816

University of Georgia
10.
Bedwell, Jeffrey Scott.
Functional magnetic resonance imaging of the magnocellular visual pathway in nonpsychotic relatives of persons with schizophrenia.
Degree: 2014, University of Georgia
URL: http://hdl.handle.net/10724/21427
► Physiological research with monkeys and psychophysical research with humans has demonstrated the ability of diffuse red light to suppress activity in the magnocellular (M) visual…
(more)
▼ Physiological research with monkeys and psychophysical research with humans has demonstrated the ability of diffuse red light to suppress activity in the magnocellular (M) visual pathway. In contrast, a previous psychophysical study found
that a subset of nonpsychotic relatives of persons with schizophrenia showed the opposite effect, suggesting a novel biobehavioral marker for the disorder. Other research suggests that persons with schizophrenia have a dysfunctional M pathway under
neutral (non-red) light conditions. However, it does not appear that these findings have been explored with physiological methods in nonpsychotic relatives, which would provide support for genetic contributions. The current study used physiological
methodology to explore whether, as a group: 1) healthy adults show suppression of the M pathway in response to diffuse red light; 2) nonpsychotic relatives of persons with schizophrenia have a dysfunctional M pathway under neutral light conditions; and
3) nonpsychotic relatives of persons with schizophrenia have a differential M pathway response to red light. Functional magnetic resonance imaging (fMRI) was used to investigate a group of 13 nonpsychotic relatives of persons with schizophrenia and 11
controls. Moving concentric rings were presented on both red and green backgrounds to stimulate the M pathway. The fMRI signal strength in bilateral cortical region V5 (MT) was measured as a marker of M pathway functioning. Statistically significant
results were limited to measures of fMRI signal in right hemisphere V5 relative to signal from bilateral V5, and suggested that: 1) the control group had reduced M pathway activity in response to diffuse red light; 2) the relative group had a hypoactive
M pathway; and 3) a subset of the relatives had the opposite M pathway response to diffuse red light. The differential M pathway response to red light in the relatives remained a statistical trend after controlling for M pathway signal from the neutral
(green) background condition. Results provide preliminary evidence that genetic risk for schizophrenia is related to a hypoactive M pathway and an independent differential response (increase in activity) of the M pathway to red light. These features may
be more evident in the right hemisphere when examining cortical region V5.
Subjects/Keywords: schizophrenia; relatives; magnocellular visual pathway; red light; V5
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Bedwell, J. S. (2014). Functional magnetic resonance imaging of the magnocellular visual pathway in nonpsychotic relatives of persons with schizophrenia. (Thesis). University of Georgia. Retrieved from http://hdl.handle.net/10724/21427
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Bedwell, Jeffrey Scott. “Functional magnetic resonance imaging of the magnocellular visual pathway in nonpsychotic relatives of persons with schizophrenia.” 2014. Thesis, University of Georgia. Accessed March 01, 2021.
http://hdl.handle.net/10724/21427.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Bedwell, Jeffrey Scott. “Functional magnetic resonance imaging of the magnocellular visual pathway in nonpsychotic relatives of persons with schizophrenia.” 2014. Web. 01 Mar 2021.
Vancouver:
Bedwell JS. Functional magnetic resonance imaging of the magnocellular visual pathway in nonpsychotic relatives of persons with schizophrenia. [Internet] [Thesis]. University of Georgia; 2014. [cited 2021 Mar 01].
Available from: http://hdl.handle.net/10724/21427.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Bedwell JS. Functional magnetic resonance imaging of the magnocellular visual pathway in nonpsychotic relatives of persons with schizophrenia. [Thesis]. University of Georgia; 2014. Available from: http://hdl.handle.net/10724/21427
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Georgia
11.
Boyd, Megan Carly.
Schizophrenia and the magnocellular system.
Degree: 2014, University of Georgia
URL: http://hdl.handle.net/10724/24079
► Previous research has shown that the Magnocellular pathway in schizophrenia patients may be hyperactive and may be suppressed using red light. This study uses a…
(more)
▼ Previous research has shown that the Magnocellular pathway in schizophrenia patients may be hyperactive and may be suppressed using red light. This study uses a Visual Backward Masking paradigm to manipulate magnocellular pathway
functioning. Participants were shown stimuli presented on a red or green background, quickly followed by a mask, and were asked to locate the stimulus on the screen or attend to a detail in the stimulus. The stimuli and mask were separated by varying
time intervals. In the red background condition, schizophrenia patients should show accuracy rates similar to non-psychiatric controls on a green background, regardless of the task. Overall, schizophrenia patients were less accurate than normal controls
on both backgrounds; however, only one time interval obtained statistical significance in the location task while two were significant in the identification task. These results suggest schizophrenia patients have general deficits, rather than only
hyperactivity, in the magnocellular pathway.
Subjects/Keywords: Schizophrenia; magnocellular pathway; visual processing; visual backward masking; hyperactivity
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Boyd, M. C. (2014). Schizophrenia and the magnocellular system. (Thesis). University of Georgia. Retrieved from http://hdl.handle.net/10724/24079
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Boyd, Megan Carly. “Schizophrenia and the magnocellular system.” 2014. Thesis, University of Georgia. Accessed March 01, 2021.
http://hdl.handle.net/10724/24079.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Boyd, Megan Carly. “Schizophrenia and the magnocellular system.” 2014. Web. 01 Mar 2021.
Vancouver:
Boyd MC. Schizophrenia and the magnocellular system. [Internet] [Thesis]. University of Georgia; 2014. [cited 2021 Mar 01].
Available from: http://hdl.handle.net/10724/24079.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Boyd MC. Schizophrenia and the magnocellular system. [Thesis]. University of Georgia; 2014. Available from: http://hdl.handle.net/10724/24079
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Wright State University
12.
Garrett, James Samuel.
Interaction of Top-Down and Bottom-Up Search with
Magnocellular- and Parvocellular-Mediated Stimuli.
Degree: PhD, Human Factors and Industrial/Organizational Psychology
PhD, 2016, Wright State University
URL: http://rave.ohiolink.edu/etdc/view?acc_num=wright1464278964
► The current study simultaneously examined the potentiality of a magnocellular attentional advantage and the competition between top-down and bottom-up processing on attention during visual search…
(more)
▼ The current study simultaneously examined the
potentiality of a
magnocellular attentional advantage and the
competition between top-down and bottom-up processing on attention
during visual search as measured by covert and overt visual
attention. Specifically, the study tested two opposing views of the
competition between top-down and bottom-up processing. The
contingent involuntary orienting hypothesis (Folk, Remington, &
Johnston, 1992), states that goal directed search is not affected
by target-irrelevant stimuli. In contrast, the distractor
interference paradigm (Theeuwes, 1994), states that goal directed
search can be affected by target-irrelevant stimuli if more salient
than the rest of the search array. The study utilized a search
array of contrast-equated orientation and spatial frequency
modulated Gabor patches to preferentially activate the
magnocellular and parvocellular visual streams in order to test for
a
magnocellular attentional advantage. Participants were asked to
find a singleton target Gabor patch amongst a field of distractor
Gabor patches. The results were mixed. Top-down search for a
spatial frequency singleton provided support for the distractor
interference paradigm while top-down search for an orientation
singleton provided support for the contingent involuntary
orientating hypothesis. These mixed results suggest top-down versus
bottom-up search is more complicated than these two theories
suggest. By demonstrating the effect of a target-irrelevant
distractor on response time and accuracy, I provide that a
bottom-up attentional priority exists when performing a top-down
search for an orientation singleton, but not for a spatial
frequency singleton. Additionally, the current study could find no
evidence for a
magnocellular attentional advantage.
Advisors/Committee Members: Watamaniuk, Scott (Advisor).
Subjects/Keywords: Psychology; visual search; top-down; bottom-up; spatial frequency; magnocellular; parvocellular
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Garrett, J. S. (2016). Interaction of Top-Down and Bottom-Up Search with
Magnocellular- and Parvocellular-Mediated Stimuli. (Doctoral Dissertation). Wright State University. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=wright1464278964
Chicago Manual of Style (16th Edition):
Garrett, James Samuel. “Interaction of Top-Down and Bottom-Up Search with
Magnocellular- and Parvocellular-Mediated Stimuli.” 2016. Doctoral Dissertation, Wright State University. Accessed March 01, 2021.
http://rave.ohiolink.edu/etdc/view?acc_num=wright1464278964.
MLA Handbook (7th Edition):
Garrett, James Samuel. “Interaction of Top-Down and Bottom-Up Search with
Magnocellular- and Parvocellular-Mediated Stimuli.” 2016. Web. 01 Mar 2021.
Vancouver:
Garrett JS. Interaction of Top-Down and Bottom-Up Search with
Magnocellular- and Parvocellular-Mediated Stimuli. [Internet] [Doctoral dissertation]. Wright State University; 2016. [cited 2021 Mar 01].
Available from: http://rave.ohiolink.edu/etdc/view?acc_num=wright1464278964.
Council of Science Editors:
Garrett JS. Interaction of Top-Down and Bottom-Up Search with
Magnocellular- and Parvocellular-Mediated Stimuli. [Doctoral Dissertation]. Wright State University; 2016. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=wright1464278964

University of Saskatchewan
13.
Star, Blanc.
Dehydration increases L-type calcium channel density in the somata of magnocellular neurosecretory cells in rats.
Degree: 2005, University of Saskatchewan
URL: http://hdl.handle.net/10388/etd-07282005-110945
► The magnocellular neurosecretory cells (MNCs) of the hypothalamus are responsible for the synthesis and secretion of vasopressin (VP), which is important for fluid homeostasis, and…
(more)
▼ The
magnocellular neurosecretory cells (MNCs) of the hypothalamus are responsible for the synthesis and secretion of vasopressin (VP), which is important for fluid homeostasis, and oxytocin (OT), which is responsible for uterine contraction during parturition and milk let-down during lactation. VP-ergic MNCs undergo a number of structural and functional changes during dehydration, including the adoption of a bursting pattern of firing, the retraction of glial processes from MNC somata and terminals, the translocation of kappa-opioid receptors from internal stores to the plasma membrane, and the somatodendritic release of VP and OT. Since voltage-gated Ca2+ channels have been found on intracellular granules, and since an increase in Ca2+ current could regulate firing patterns and neuropeptide release, the surface expression of Ca2+ channel subtypes in MNCs was tested to determine if it would be altered by 16-24 hours of water deprivation. Using radioligand binding of antagonists of N-type and L-type Ca2+ channels, channel density was measured in the supraoptic nucleus (SON), which is largely composed of MNC somata, and in the neurohypophysis (NH), which is largely composed of MNC terminals. Dehydration caused an increase in the density of L-type channels in the SON, while causing no significant change in the N-type density. No change in density of either channel type was observed in the NH. Electrophysiological measurements in isolated MNC somata showed no change in total Ca2+ current, but a significant increase in the nifedipine-sensitive current following dehydration. Reverse transcription-polymerase chain reaction (RT-PCR) demonstrated no increase in messenger RNA levels for L-type channels, suggesting that the increase in channel density is not a consequence of de novo synthesis. These results suggest that L-type Ca2+ channels may be translocated from internal stores to the plasma membrane of MNCs in response to dehydration. Such a process may be important in maximizing secretion of VP when the physiological need is high.
Advisors/Committee Members: Fisher, Thomas E., Walz, Wolfgang, Tuchek, John M., Sulakhe, Prakash, Desautels, Michel.
Subjects/Keywords: magnocellular neurosecretory cells; dehydration; calcium channels
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Star, B. (2005). Dehydration increases L-type calcium channel density in the somata of magnocellular neurosecretory cells in rats. (Thesis). University of Saskatchewan. Retrieved from http://hdl.handle.net/10388/etd-07282005-110945
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Star, Blanc. “Dehydration increases L-type calcium channel density in the somata of magnocellular neurosecretory cells in rats.” 2005. Thesis, University of Saskatchewan. Accessed March 01, 2021.
http://hdl.handle.net/10388/etd-07282005-110945.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Star, Blanc. “Dehydration increases L-type calcium channel density in the somata of magnocellular neurosecretory cells in rats.” 2005. Web. 01 Mar 2021.
Vancouver:
Star B. Dehydration increases L-type calcium channel density in the somata of magnocellular neurosecretory cells in rats. [Internet] [Thesis]. University of Saskatchewan; 2005. [cited 2021 Mar 01].
Available from: http://hdl.handle.net/10388/etd-07282005-110945.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Star B. Dehydration increases L-type calcium channel density in the somata of magnocellular neurosecretory cells in rats. [Thesis]. University of Saskatchewan; 2005. Available from: http://hdl.handle.net/10388/etd-07282005-110945
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
14.
Mumtaz, Naima.
Acute and chronic adaptation of Supraoptic neurons to changes in osmolality.
Degree: 2011, University of Saskatchewan
URL: http://hdl.handle.net/10388/etd-05262011-102523
► Vasopressin (VP) is an antidiuretic hormone that is synthesized and released by osmosensitive magnocellular neurosecretory cells (MNCs) to regulate water homeostasis in the body. The…
(more)
▼ Vasopressin (VP) is an antidiuretic hormone that is synthesized and released by osmosensitive
magnocellular neurosecretory cells (MNCs) to regulate water homeostasis in the body. The rate and firing pattern of MNCs determines the amount of VP release, which is elevated during physiological stress particularly dehydration. During acute osmotic changes the MNCs shrink and swell due to hypertonic and hypotonic stimuli, respectively. In contrast to hippocampal neurons, which display regulatory volume increases (RVI) and regulatory volume decreases (RVD) in response to hypertonic and hypotonic stimuli, MNCs do not have compensatory mechanisms. The MNCs undergo hypertrophy as a part of their physiological structural and functional plasticity during chronic dehydration. These changes are thought to be important during long term osmotic changes for the sustained and high level releases of hormone. However, the mechanism of hypertrophy is still unclear and it is difficult to address this issue in vivo. We therefore undertook studies on acutely isolated MNCs to test hypertrophy in MNCs. We observed that acutely isolated MNCs treated with hyperosmolar solution (325 mOsmol kg-1) for 150 minutes in vitro showed hypertrophy (a 9% increase in CSA) and recovered their original size when returned to isotonic solution (295 mOsmol kg-1) for another 60 minutes. Whole cell patch clamp experiments showed a 34% increase in cell membrane capacitance following treatment with hypertonic solution for 90-150 minutes. The osmotically-evoked hypertrophic response was blocked by using a TAT (human immunodeficiency virus transactivator of transcription) peptide (TAT-NSF700) that prevents SNARE-mediated exocytotic fusion by blocking the function of NSF (N-ethylmaleimide-sensitive factor). The hypertrophic response did not appear to be altered by a scrambled version of the peptide, showing that osmotically-evoked hypertrophy depends on SNARE-mediated exocytotic fusion. The VP and OT-MNCs exposed to hyperosmolar solution for two hours showed increased immunofluorescence for L-type Ca²⁺ channels (both Cav1.2 and Cav1.3). Our data suggest that the osmotically-evoked hypertrophy is associated with an increase in the total membrane surface area due to the exocytotic fusion of intracellular granules with the plasma membrane and with increased expression of L-type Ca2+ channels. This study will be helpful in understanding of the adaptation that MNCs undergo during long term dehydration and pathological conditions that lead to increased plasma osmolality.
Advisors/Committee Members: Fisher, Thomas E., Mulligan, Sean, Desautels, Michel, West, Nigel, Muir, Gillian.
Subjects/Keywords: adaptation; Magnocellular neurosecretory cells; Osmolality
…receptor
MARCKS
Myristoylated alanine-rich C kinase substrate
MNC
Magnocellular… …x28;Bourque, 2008).
1.1.2 The magnocellular neurosecretory cells (MNCs)
The… …primary osmoreceptors are known as magnocellular neurosecretory cells (MNCs), which…
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Mumtaz, N. (2011). Acute and chronic adaptation of Supraoptic neurons to changes in osmolality. (Thesis). University of Saskatchewan. Retrieved from http://hdl.handle.net/10388/etd-05262011-102523
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Mumtaz, Naima. “Acute and chronic adaptation of Supraoptic neurons to changes in osmolality.” 2011. Thesis, University of Saskatchewan. Accessed March 01, 2021.
http://hdl.handle.net/10388/etd-05262011-102523.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Mumtaz, Naima. “Acute and chronic adaptation of Supraoptic neurons to changes in osmolality.” 2011. Web. 01 Mar 2021.
Vancouver:
Mumtaz N. Acute and chronic adaptation of Supraoptic neurons to changes in osmolality. [Internet] [Thesis]. University of Saskatchewan; 2011. [cited 2021 Mar 01].
Available from: http://hdl.handle.net/10388/etd-05262011-102523.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Mumtaz N. Acute and chronic adaptation of Supraoptic neurons to changes in osmolality. [Thesis]. University of Saskatchewan; 2011. Available from: http://hdl.handle.net/10388/etd-05262011-102523
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
15.
Lenoble, Quentin.
Etude psychophysique des systèmes visuels magnocellulaire et parvocellulaire dans le vieillissement normal et proposition de réhabilitation des déficits : une approche en neuropsychologie cognitive : Psychophysical study of the magnocellular and parvocellular visual systems in normal aging and rehabilitation of deficits : approach a neuropsychological.
Degree: Docteur es, Psychologie, 2011, Université de Bordeaux Segalen
URL: http://www.theses.fr/2011BOR21829
► Cette thèse avait pour principal objectif d’étudier la dissociation du système magnocellulaire et parvocellulaire en testant l’évolution de ces systèmes dans le vieillissement normal et…
(more)
▼ Cette thèse avait pour principal objectif d’étudier la dissociation du système magnocellulaire et parvocellulaire en testant l’évolution de ces systèmes dans le vieillissement normal et la réhabilitation à l’aide de lunettes à filtre jaune. Pour cela deux paradigmes expérimentaux dont les caractéristiques des stimuli permettaient de biaiser le traitement visuel vers l’un ou l’autre des deux systèmes et dont les tâches impliquaient un niveau de traitement cognitif plus ou moins élaboré ont été utilisés. A l’aide d’une tâche de discrimination de luminance, les travaux ont mis en évidence l’apparition d’un déficit parvocellulaire massif dans le vieillissement ainsi qu’un déficit magnocellulaire de moindre ampleur au début du vieillissement mais qui s’accentuait rapidement au-delà de 75 ans. Dans une tâche de catégorisation d’objets, la présence du déficit magnocellulaire avec l’âge et le grand âge a été corroborée mais aucune répercussion du déficit parvocellulaire mis en évidence à un niveau de traitement plus précoce n’a été observée dans cette tâche. Concernant la réhabilitation, seul le groupe de participants très âgé (>75 ans) a vu ses performances améliorées par le filtre jaune dans la condition impliquant spécifiquement le système magnocellulaire à l’épreuve de discrimination de luminance. Dans l’épreuve de catégorisation, les deux groupes de participants âgés et très âgés ont montré une diminution significative de leur temps de réponse avec le filtre jaune accompagnée d’une amélioration de la précision de catégorisation pour le groupe très âgé, spécifiquement dans la condition mettant en jeu le système magnocellulaire.L’ensemble des résultats confirment donc la dissociation neuropsychologique entre système magnocellulaire et parvocellulaire : ils peuvent être sollicités de façon privilégiée chez l’adulte jeune en faisant varier à la fois plusieurs caractéristiques de la stimulation et la tâche ; ils ne vieillissent pas au même rythme et l’un d’entre eux peut être spécifiquement réhabilité
The thesis aimed at studying the dissociation between the magnocellular and the parvocellular system by testing their evolution in normal aging and their rehabilitation with yellow filter glasses. Two experimental paradigms whose specific stimuli characteristics and task allow to bias visual processing toward one or the other system and which involved a low or an elaborated cognitive processing were used.In a luminance discrimination task, the results showed a massive parvocellular and a lower magnocellular deficit at the beginning of aging, but the magnocellular deficit increased rapidly beyond 75 years old. In an object categorization task, the presence of magnocellular deficit with age and very old age was corroborated but there was no parvocellular deficit suggesting that the parvocellular deficit found at earlier stage of processing had no consequence for higher-level processes.Regarding rehabilitation, yellow filter improved sensitivity in the discrimination of luminance specifically in the condition involving the…
Advisors/Committee Members: Semal, Catherine (thesis director), Delord, Sandrine (thesis director).
Subjects/Keywords: Magnocellulaire; Parvocellulaire; Vieillissement; Contraste; Catégorisation; Magnocellular; Parvocellular; Age-related change; Contrast gain; Categorization
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APA ·
Chicago ·
MLA ·
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APA (6th Edition):
Lenoble, Q. (2011). Etude psychophysique des systèmes visuels magnocellulaire et parvocellulaire dans le vieillissement normal et proposition de réhabilitation des déficits : une approche en neuropsychologie cognitive : Psychophysical study of the magnocellular and parvocellular visual systems in normal aging and rehabilitation of deficits : approach a neuropsychological. (Doctoral Dissertation). Université de Bordeaux Segalen. Retrieved from http://www.theses.fr/2011BOR21829
Chicago Manual of Style (16th Edition):
Lenoble, Quentin. “Etude psychophysique des systèmes visuels magnocellulaire et parvocellulaire dans le vieillissement normal et proposition de réhabilitation des déficits : une approche en neuropsychologie cognitive : Psychophysical study of the magnocellular and parvocellular visual systems in normal aging and rehabilitation of deficits : approach a neuropsychological.” 2011. Doctoral Dissertation, Université de Bordeaux Segalen. Accessed March 01, 2021.
http://www.theses.fr/2011BOR21829.
MLA Handbook (7th Edition):
Lenoble, Quentin. “Etude psychophysique des systèmes visuels magnocellulaire et parvocellulaire dans le vieillissement normal et proposition de réhabilitation des déficits : une approche en neuropsychologie cognitive : Psychophysical study of the magnocellular and parvocellular visual systems in normal aging and rehabilitation of deficits : approach a neuropsychological.” 2011. Web. 01 Mar 2021.
Vancouver:
Lenoble Q. Etude psychophysique des systèmes visuels magnocellulaire et parvocellulaire dans le vieillissement normal et proposition de réhabilitation des déficits : une approche en neuropsychologie cognitive : Psychophysical study of the magnocellular and parvocellular visual systems in normal aging and rehabilitation of deficits : approach a neuropsychological. [Internet] [Doctoral dissertation]. Université de Bordeaux Segalen; 2011. [cited 2021 Mar 01].
Available from: http://www.theses.fr/2011BOR21829.
Council of Science Editors:
Lenoble Q. Etude psychophysique des systèmes visuels magnocellulaire et parvocellulaire dans le vieillissement normal et proposition de réhabilitation des déficits : une approche en neuropsychologie cognitive : Psychophysical study of the magnocellular and parvocellular visual systems in normal aging and rehabilitation of deficits : approach a neuropsychological. [Doctoral Dissertation]. Université de Bordeaux Segalen; 2011. Available from: http://www.theses.fr/2011BOR21829

University of Illinois – Chicago
16.
Hall, Cierra Michelle.
A Luminance Noise Approach to Target Post-Receptor Visual Pathways; Application to Optic Nerve Disease.
Degree: 2016, University of Illinois – Chicago
URL: http://hdl.handle.net/10027/21610
► Contrast sensitivity (CS), which is the ability to detect small differences in luminance, is a fundamental task of the visual system and loss of CS…
(more)
▼ Contrast sensitivity (CS), which is the ability to detect small differences in luminance, is a fundamental task of the visual system and loss of CS is an important marker for many disease states. Although clinically-applicable methods are available to assess CS, there are limitations to these standard methods. For example, they are unable to determine which of the two primary post-receptor visual pathways, the
magnocellular (MC) and parvocellular (PC) pathways, mediates CS for a given task. Furthermore, standard clinical measures of CS cannot provide insight into mechanisms underlying CS abnormalities.
In this thesis, a test of CS using letter stimuli will be developed and applied to address these issues. To permit the development of this new CS test, the following series of questions will first be resolved and an optimized CS test will then be applied to patients who have optic nerve dysfunction to better understand their CS deficits. Question 1: Which optotypes should be used in tests of letter CS? Letters are relatively complex targets that are not all equally identifiable. Aim 1 will define the optimal letter set for use in CS testing. Question 2: Can luminance noise, defined as decrements and increments of luminance added to a stimulus (e.g. ‘tv snow’), be used to target the MC and PC pathways? Although there is preliminary evidence that the temporal characteristics of noise can be manipulated to target these post receptor pathways selectively, the specific characteristics of noise needed to do so have not been fully defined. Aim 2 will determine the spatial and temporal characteristics of noise capable of targeting the MC and PC pathways. Question 3: What is the optimal letter size for use in targeting the MC and PC pathways using static and dynamic luminance noise? Aim 3 will determine the range of letter sizes that can be used to target selectively the MC and PC pathways. Question 4: What is the optimal letter duration for use in targeting the MC and PC pathways in noise-based CS tests? Aim 4 will evaluate the ability of static and dynamic noise to target the MC and PC pathways across a series of letter exposure durations. Once the test is developed and finalized, it will be applied in Aim 5 to a small sample of patients who have optic neuritis (ON); the results from the patients will be compared to visually-normal control subjects.
Thus, this dissertation will develop a clinically applicable, noise-based test of letter CS that can independently assess function within the MC and PC pathways. This will permit evaluating potential deficits within the MC and PC pathways, as well as provide preliminary insight into potential factors that limit CS in patients who have ON.
Advisors/Committee Members: McAnany, J. Jason (advisor), Patton, James (committee member), Hetling, John (committee member), Cao, Dingcai (committee member), Royston, Thomas (chair).
Subjects/Keywords: luminance noise; contrast sensitivity; magnocellular pathway; parvocellular pathway; optic neuritis; internal noise; efficiency; object frequency
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Hall, C. M. (2016). A Luminance Noise Approach to Target Post-Receptor Visual Pathways; Application to Optic Nerve Disease. (Thesis). University of Illinois – Chicago. Retrieved from http://hdl.handle.net/10027/21610
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Hall, Cierra Michelle. “A Luminance Noise Approach to Target Post-Receptor Visual Pathways; Application to Optic Nerve Disease.” 2016. Thesis, University of Illinois – Chicago. Accessed March 01, 2021.
http://hdl.handle.net/10027/21610.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Hall, Cierra Michelle. “A Luminance Noise Approach to Target Post-Receptor Visual Pathways; Application to Optic Nerve Disease.” 2016. Web. 01 Mar 2021.
Vancouver:
Hall CM. A Luminance Noise Approach to Target Post-Receptor Visual Pathways; Application to Optic Nerve Disease. [Internet] [Thesis]. University of Illinois – Chicago; 2016. [cited 2021 Mar 01].
Available from: http://hdl.handle.net/10027/21610.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Hall CM. A Luminance Noise Approach to Target Post-Receptor Visual Pathways; Application to Optic Nerve Disease. [Thesis]. University of Illinois – Chicago; 2016. Available from: http://hdl.handle.net/10027/21610
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Queens University
17.
Ranepura, Nipuni.
Comparison of Pyramidal and Magnocellular Neuroendocrine Cell Volume Responses to Osmotic Stress and Stroke - Like Stress
.
Degree: Neuroscience Studies, 2011, Queens University
URL: http://hdl.handle.net/1974/6312
► Acute brain cell swelling (cytotoxic edema) can occur in the first minutes of stroke, presumably as a result of brain cells taking up water. In…
(more)
▼ Acute brain cell swelling (cytotoxic edema) can occur in the first minutes of stroke, presumably as a result of brain cells taking up water. In extreme hypo-osmotic situations such as excessive water-loading by patients, uptake by brain cells can expand the brain, causing seizures. But is ischemic brain cell swelling the same as hypo-osmotic swelling?
Water can passively diffuse across the plasma membrane. However the presence of water channels termed aquaporins (AQP) facilitates passive water diffusion by 10-100 times. Unlike astrocytes, there is no evidence of water channels on neuronal plasma membrane. However, there is still much debate about which cells (neurons or astrocytes) swell during over-hydration or during stroke and if neurons and astrocytes can volume-regulate during osmotic stress.
The purpose of this study was to examine and compare the volume responses of PyNs and magnocellular neuroendocrine cells (MNCs) to acute osmotic challenge and to OGD. We examined MNCs because they are intrinsically osmosensitive to small changes (2-3 mOsm) of plasma osmolality. We also examined if the same neurons behave similarly in brain slices or when dissociated and if they respond differently to acute osmotic stress and stroke-like stress.
Our results indicate that during acute osmotic stress (±40 mOsm) half of dissociated PyNs and MNCs tended to show appropriate responses. MNCs in brain slices showed similar responses to when they were dissociated, while brain slice PyNs were less responsive than when dissociated. Exposure to OGD resulted in obvious differences between the two types of in vitro preparations. Dissociated PyNs and MNCs showed no consistency in their volume responses to 10 minutes of OGD. Dissociated neurons swelled, shrunk or were unchanged in about equal numbers. In contrast, brain slice PyNs underwent profound swelling whereas, brain slice MNCs showed minor volume decreases.
We conclude that about half of our dissociated neurons were too variable and unpredictable in their osmotic volume responses to be useful for osmotic studies. They also were too resistant to stroke-like stress to be good models for ischemia. Brain slice neurons were similar in their osmotic responses to dissociated neurons but proved to have consistent and predictable responses to stroke-like stress.
Subjects/Keywords: Pyramidal Neurons
;
Magnocellular Neuroendocrine Cell
;
Osmotic Stress
;
Oxygen Glucose Deprivation
;
Paraventricular Nucleus
;
Supraoptic Nucleus
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Ranepura, N. (2011). Comparison of Pyramidal and Magnocellular Neuroendocrine Cell Volume Responses to Osmotic Stress and Stroke - Like Stress
. (Thesis). Queens University. Retrieved from http://hdl.handle.net/1974/6312
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Ranepura, Nipuni. “Comparison of Pyramidal and Magnocellular Neuroendocrine Cell Volume Responses to Osmotic Stress and Stroke - Like Stress
.” 2011. Thesis, Queens University. Accessed March 01, 2021.
http://hdl.handle.net/1974/6312.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Ranepura, Nipuni. “Comparison of Pyramidal and Magnocellular Neuroendocrine Cell Volume Responses to Osmotic Stress and Stroke - Like Stress
.” 2011. Web. 01 Mar 2021.
Vancouver:
Ranepura N. Comparison of Pyramidal and Magnocellular Neuroendocrine Cell Volume Responses to Osmotic Stress and Stroke - Like Stress
. [Internet] [Thesis]. Queens University; 2011. [cited 2021 Mar 01].
Available from: http://hdl.handle.net/1974/6312.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Ranepura N. Comparison of Pyramidal and Magnocellular Neuroendocrine Cell Volume Responses to Osmotic Stress and Stroke - Like Stress
. [Thesis]. Queens University; 2011. Available from: http://hdl.handle.net/1974/6312
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Georgia
18.
Narang, Shruti.
Exploring the contribution of the magnocellular pathway in filling-in of artificial scotoma.
Degree: 2015, University of Georgia
URL: http://hdl.handle.net/10724/31254
► Perceptual illusions and disorders often provide insights into normal visual mechanisms. Artificial scotoma is a type of illusion where our visual system loses perception of…
(more)
▼ Perceptual illusions and disorders often provide insights into normal visual mechanisms. Artificial scotoma is a type of illusion where our visual system loses perception of a peripheral target on a dynamic noise background over several
seconds. Several studies have shown that specific sensory manipulations like the size of target and background temporal variations affects the time taken for a target to fade. There is no unifying theory to account for the sensory factors that play a
major role in determining the length of time taken to fade. The experiments described here explored the relation between sensory factors preferentially processed by the magnocellular pathway and the time taken to induce a scotoma. In addition to
measuring time taken to fade, the duration of time a target stayed invisible was also measured. The two measures were recorded for conditions that either stimulate the magnocellular pathway or reduced its response relative to engaging the parvocellular
pathway. The results indicate that altering the background characteristics by using different flicker rates, diffuse red light, and a background pulsed pedestal affected time to fade and the probability of fading. The spatial frequency within the target
region affected the duration of fading. Time taken to fade seems to be modulated by background characteristics while the time taken to reappear seems to be more modulated by target region characteristics indicating the role of competition between figure
and ground. The results provide strong support for the role of visual pathways and figure-ground segregation mechanisms in the perceptual filling-in of a scotoma.
Subjects/Keywords: Magnocellular and Parvocellular Visual Pathways; Artificial Scotoma; Perceptual Filling-in; Figure-Ground Segregation; Texture; Contrast
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Narang, S. (2015). Exploring the contribution of the magnocellular pathway in filling-in of artificial scotoma. (Thesis). University of Georgia. Retrieved from http://hdl.handle.net/10724/31254
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Narang, Shruti. “Exploring the contribution of the magnocellular pathway in filling-in of artificial scotoma.” 2015. Thesis, University of Georgia. Accessed March 01, 2021.
http://hdl.handle.net/10724/31254.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Narang, Shruti. “Exploring the contribution of the magnocellular pathway in filling-in of artificial scotoma.” 2015. Web. 01 Mar 2021.
Vancouver:
Narang S. Exploring the contribution of the magnocellular pathway in filling-in of artificial scotoma. [Internet] [Thesis]. University of Georgia; 2015. [cited 2021 Mar 01].
Available from: http://hdl.handle.net/10724/31254.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Narang S. Exploring the contribution of the magnocellular pathway in filling-in of artificial scotoma. [Thesis]. University of Georgia; 2015. Available from: http://hdl.handle.net/10724/31254
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Georgia
19.
Guenther, Benjamin Aaron.
Influences of abrupt vs. ramped stimulus presentation on location-based inhibition of return.
Degree: 2014, University of Georgia
URL: http://hdl.handle.net/10724/24621
► Recent work has illustrated the importance of a sensory component to inhibition of return (IOR). A recent study exploring the contributions from the parvocellular (P)…
(more)
▼ Recent work has illustrated the importance of a sensory component to inhibition of return (IOR). A recent study exploring the contributions from the parvocellular (P) and magnocellular (M) pathways to location based IOR through bottom-up
sensory (target spatial frequency) and top-down attentional (objects) manipulations (Brown & Guenther, 2008) suggests conditions favoring P/ventral relative to M/dorsal processing should produce greater IOR magnitude and vice versa. To further
explore the roles of the P and M pathways to IOR, the present study used a different sensory manipulation presenting cues and targets either abruptly (producing a strong M response) or ramped on and off (producing a relatively weaker M response). Greater
IOR was expected to ramped targets because of the weaker M response. Less IOR was expected to abrupt targets due to a greater M response. This particular sensory manipulation by itself was unable to produce differences in IOR; however, when combined with
increased P/ventral activity due to the presence of objects (2-D or 3-D) differences in IOR between abrupt and ramped conditions emerged. The results highlight the importance of sensory factors on IOR and provide an example of how they can interact with
other perceptual variables to influence IOR.
Subjects/Keywords: Attention; Location IOR; Object IOR; Parvocellular and Magnocellular Pathways; Ramped stimulus presentation
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Guenther, B. A. (2014). Influences of abrupt vs. ramped stimulus presentation on location-based inhibition of return. (Thesis). University of Georgia. Retrieved from http://hdl.handle.net/10724/24621
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Guenther, Benjamin Aaron. “Influences of abrupt vs. ramped stimulus presentation on location-based inhibition of return.” 2014. Thesis, University of Georgia. Accessed March 01, 2021.
http://hdl.handle.net/10724/24621.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Guenther, Benjamin Aaron. “Influences of abrupt vs. ramped stimulus presentation on location-based inhibition of return.” 2014. Web. 01 Mar 2021.
Vancouver:
Guenther BA. Influences of abrupt vs. ramped stimulus presentation on location-based inhibition of return. [Internet] [Thesis]. University of Georgia; 2014. [cited 2021 Mar 01].
Available from: http://hdl.handle.net/10724/24621.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Guenther BA. Influences of abrupt vs. ramped stimulus presentation on location-based inhibition of return. [Thesis]. University of Georgia; 2014. Available from: http://hdl.handle.net/10724/24621
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Queensland University of Technology
20.
Maynard, Michelle Lorraine.
Dynamics of rod and cone photoreceptor interactions under mesopic light levels.
Degree: 2012, Queensland University of Technology
URL: https://eprints.qut.edu.au/52772/
► Visual adaptation regulates contrast sensitivity during dynamically changing light conditions (Crawford, 1947; Hecht, Haig & Chase, 1937). These adaptation dynamics are unknown under dim (mesopic)…
(more)
▼ Visual adaptation regulates contrast sensitivity during dynamically changing light conditions (Crawford, 1947; Hecht, Haig & Chase, 1937). These adaptation dynamics are unknown under dim (mesopic) light levels when the rod (R) and long (L), medium (M) and short (S) wavelength cone photoreceptor classes contribute to vision via interactions in shared non-opponent Magnocellular (MC), chromatically opponent Parvocellular (PC) and Koniocellular (KC) visual pathways (Dacey, 2000). This study investigated the time-course of adaptation and post-receptoral pathways mediating receptor specific rod and cone interactions under mesopic illumination. A four-primary photostimulator (Pokorny, Smithson & Quinlan, 2004) was used to independently control the activity of the four photoreceptor classes and their post-receptoral visual athways in human observers.
In the first experiment, the contrast sensitivity and time-course of visual adaptation under mesopic illumination were measured for receptoral (L, S, R) and post-receptoral (LMS, LMSR, L-M) stimuli. An incremental (Rapid-ON) sawtooth conditioning pulse biased detection to ON-cells within the visual pathways and sensitivity was assayed relative to pulse onset using a briefly presented incremental probe that did not alter adaptation. Cone.Cone interactions with luminance stimuli (L cone, LMS, LMSR) reduced sensitivity by 15% and the time course of recovery was 25± 5ms-1 (μ ± SEM). PC mediated (+L-M) chromatic stimuli sensitivity loss was less (8%) than for luminance and recovery was slower (μ = 2.95 ± 0.05 ms-1), with KC mediated (S cone) chromatic stimuli showing a high sensitivity loss (38%) and the slowest recovery time (1.6 ± 0.2 ms-1). Rod-Rod interactions increased sensitivity by 20% and the time course of recovery was 0.7 ± 0.2 ms-1 (μ ± SD). Compared to these interaction types, Rod-Cone interactions reduced sensitivity to a lesser degree (5%) and showed the fastest recovery (μ = 43 ± 7 ms-1).
In the second experiment, rod contribution to the magnocellular, parvocellular and koniocellular post-receptoral pathways under mesopic illumination was determined as a function of incremental stimulus duration and waveform (rectangular; sawtooth) using a rod colour match procedure (Cao, Pokorny & Smith, 2005; Cao, Pokorny, Smith & Zele, 2008a). For a 30% rod increment, a cone match required a decrease in [L/(L+M)] and an increase in [L+M] and [S/(L+M)], giving a greenish-blue and brighter appearance for probe durations of 75 ms or longer. Probe durations less than 75 ms showed an increase in [L+M] and no change in chromaticity [L/(L+M) or S/(L+M)], uggesting mediation by the MC pathway only for short duration rod stimuli.
s We advance previous studies by determining the time-course and nature of photoreceptor specific retinal interactions in the three post-receptoral pathways under mesopic illumination. In the first experiment, the time-course of adaptation for ON cell processing was determined, revealing opponent cell facilitation in chromatic PC and KC pathways. The…
Subjects/Keywords: mesopic; photoreceptor; adaptation; rod-cone interaction; temporal dynamics; conditioning pulse; test probe; Magnocellular (MC); Parvocellular (PC); Koniocellular (KC) post-receptoral pathways
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Maynard, M. L. (2012). Dynamics of rod and cone photoreceptor interactions under mesopic light levels. (Thesis). Queensland University of Technology. Retrieved from https://eprints.qut.edu.au/52772/
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Maynard, Michelle Lorraine. “Dynamics of rod and cone photoreceptor interactions under mesopic light levels.” 2012. Thesis, Queensland University of Technology. Accessed March 01, 2021.
https://eprints.qut.edu.au/52772/.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Maynard, Michelle Lorraine. “Dynamics of rod and cone photoreceptor interactions under mesopic light levels.” 2012. Web. 01 Mar 2021.
Vancouver:
Maynard ML. Dynamics of rod and cone photoreceptor interactions under mesopic light levels. [Internet] [Thesis]. Queensland University of Technology; 2012. [cited 2021 Mar 01].
Available from: https://eprints.qut.edu.au/52772/.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Maynard ML. Dynamics of rod and cone photoreceptor interactions under mesopic light levels. [Thesis]. Queensland University of Technology; 2012. Available from: https://eprints.qut.edu.au/52772/
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
21.
Bayle, Dimitri.
Traitement cérébral de l’expression faciale de peur : vision périphérique et effet de l’attention : Central processing of fearful faces : peripheral vision and attention effect.
Degree: Docteur es, Neuroscience, 2009, Université Claude Bernard – Lyon I
URL: http://www.theses.fr/2009LYO10227
► L’expression faciale de peur constitue un important vecteur d’information sociale mais aussi environnementale. En condition naturelle, les visages apeurés apparaissent principalement dans notre champ visuel…
(more)
▼ L’expression faciale de peur constitue un important vecteur d’information sociale mais aussi environnementale. En condition naturelle, les visages apeurés apparaissent principalement dans notre champ visuel périphérique. Cependant, les mécanismes cérébraux qui sous-tendent la perception de l’expression faciale de peur en périphérie restent largement méconnus. Nous avons démontré, grâce à des études comportementales, des enregistrements magnétoencéphalographiques et intracrâniens, que la perception de l’expression faciale de peur est efficace en grande périphérie. La perception de la peur en périphérie génère une réponse rapide de l’amygdale et du cortex frontal, mais également une réponse plus tardive dans les aires visuelles occipitales et temporales ventrales. Le contrôle attentionnel est capable d’inhiber la réponse précoce à l’expression de peur, mais également d’augmenter les activités postérieures plus tardives liées à la perception des visages. Nos résultats montrent non seulement que les réseaux impliqués dans la perception de la peur sont adaptés à la vision périphérique, mais ils mettent également en avant une nouvelle forme d’investigation des mécanismes de traitement de l’expression faciale, pouvant conduire à une meilleure compréhension des mécanismes de traitement des messages sociaux dans des situations plus écologiques.
Facial expression of fear is an important vector of social and environmental information. In natural conditions, the frightened faces appear mainly in our peripheral visual field. However, the brain mechanisms underlying perception of fear in the periphery remain largely unknown. We have demonstrated, through behavioral, magnetoencephalographic and intracranial studies that the perception of fear facial expression is efficient in large peripheral visual field. Fear perception in the periphery produces an early response in the amygdala and the frontal cortex, and a later response in the occipital and infero-temporal visual areas. Attentional control is able to inhibit the early response to fear expression and to increase the later temporo-occipital activities linked to face perception. Our results show that networks involved in fear perception are adapted to the peripheral vision. Moreover, they validate a new form of investigation of facial expression processing, which may lead to a better understanding of how we process social messages in more ecological situations.
Advisors/Committee Members: Krolak-Salmon, Pierre (thesis director).
Subjects/Keywords: Expression faciale; Peur; Amygdale; Magnétoencéphalographie,; SEEG; Périphérie; Attention; Magnocellulaire; Facial expression; Fear; Amygdala; Magnetoencephalography; Intracranial EEG; Peripheral vision; Attention; Magnocellular
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
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APA (6th Edition):
Bayle, D. (2009). Traitement cérébral de l’expression faciale de peur : vision périphérique et effet de l’attention : Central processing of fearful faces : peripheral vision and attention effect. (Doctoral Dissertation). Université Claude Bernard – Lyon I. Retrieved from http://www.theses.fr/2009LYO10227
Chicago Manual of Style (16th Edition):
Bayle, Dimitri. “Traitement cérébral de l’expression faciale de peur : vision périphérique et effet de l’attention : Central processing of fearful faces : peripheral vision and attention effect.” 2009. Doctoral Dissertation, Université Claude Bernard – Lyon I. Accessed March 01, 2021.
http://www.theses.fr/2009LYO10227.
MLA Handbook (7th Edition):
Bayle, Dimitri. “Traitement cérébral de l’expression faciale de peur : vision périphérique et effet de l’attention : Central processing of fearful faces : peripheral vision and attention effect.” 2009. Web. 01 Mar 2021.
Vancouver:
Bayle D. Traitement cérébral de l’expression faciale de peur : vision périphérique et effet de l’attention : Central processing of fearful faces : peripheral vision and attention effect. [Internet] [Doctoral dissertation]. Université Claude Bernard – Lyon I; 2009. [cited 2021 Mar 01].
Available from: http://www.theses.fr/2009LYO10227.
Council of Science Editors:
Bayle D. Traitement cérébral de l’expression faciale de peur : vision périphérique et effet de l’attention : Central processing of fearful faces : peripheral vision and attention effect. [Doctoral Dissertation]. Université Claude Bernard – Lyon I; 2009. Available from: http://www.theses.fr/2009LYO10227

University of Edinburgh
22.
Monteiro, Olivia F. de S.
Mechanisms of dendritic peptide release.
Degree: PhD, 2010, University of Edinburgh
URL: http://hdl.handle.net/1842/4420
► Magnocellular neurones (MCNs) are capable of secreting vasopressin and oxytocin from the somato-dendritic compartment, which can occur independently to secretion from nerve terminals. One hypothesis…
(more)
▼ Magnocellular neurones (MCNs) are capable of secreting vasopressin and oxytocin from the somato-dendritic compartment, which can occur independently to secretion from nerve terminals. One hypothesis of the mechanism that regulates this differential release is that dendrites utilise different vesicle pools compared to those found in terminals. Little is known for the function of neuronal dendrites, especially the mechanism for peptide release. One theory is that vesicles stored in dendrites are non-released vesicles ready for recycling or degradation. Immunofluorescent labelling was performed on hypothalamic slices of the transgenic rat where enhanced green fluorescent protein (eGFP) was tagged to vasopressin. Lysosomes were detected by the lysosome-associated membrane protein LAMP1. Correlation analysis of LAMP1 labelling and VP-eGFP had shown that localisation of lysosomes in dendrites is positively correlated to loci of high vasopressin expression. This suggests active degradation of vesicles in dendrites. It is not known whether preferential release of peptides occurs along the profile of dendrites. Experiments were carried out using a temperature block to block exit of vesicles from the Golgi apparatus. Release of the temperature block triggered release of a wave of newly synthesised vesicles from the Golgi apparatus. Measurement of the fluorescent intensity of VP-eGFP showed that preferential release of peptides does not occur along the profile of dendrites. I have also utilised confocal live cell imaging to study the dynamics of dendritic vasopressin release using VP-eGFP slice explants. Experiments using high potassium stimulation showed significant increase in the release of vasopressin after priming with thapsigargin (intracellular calcium mobiliser), in accordance to in vitro release and microdialysis studies. These results demonstrate that live cell imaging can be achieved in magnocellular neurons, providing a robust model system in the study of dendritic peptide release. Large dense core vesicles (LDCVs) in other cell types such as bovine adrenal chromaffin cells were shown to segregate according to vesicle age, suggesting that vesicle age is an important factor in the regulation of peptide release. Whether vesicles of different age groups exist in magnocellular dendrites is not known. Thus, biolistic transfection with exogenous fluorescent proteins for expression under temporal control was carried out. However, low transfection rate in magnocellular neurones and the high background fluorescence caused by scattered gold particles used as bullets for transfection deemed this method inappropriate for the purpose of imaging vesicles. Hence, development of an adenoviral transduction system was employed. By using an inducible adenovirus gene construct coupled with a fluorescent reporter gene, it is possible to visualise vesicle pool segregation under different experimental conditions. Subcloning of a red fluorescent construct tagged to ppANF was tested on PC12 cells to show targeting of fluorescence expression…
Subjects/Keywords: 612.8; Magnocellular neurones; vasopressin; neuronal dendrites; peptides; oxytocin
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Monteiro, O. F. d. S. (2010). Mechanisms of dendritic peptide release. (Doctoral Dissertation). University of Edinburgh. Retrieved from http://hdl.handle.net/1842/4420
Chicago Manual of Style (16th Edition):
Monteiro, Olivia F de S. “Mechanisms of dendritic peptide release.” 2010. Doctoral Dissertation, University of Edinburgh. Accessed March 01, 2021.
http://hdl.handle.net/1842/4420.
MLA Handbook (7th Edition):
Monteiro, Olivia F de S. “Mechanisms of dendritic peptide release.” 2010. Web. 01 Mar 2021.
Vancouver:
Monteiro OFdS. Mechanisms of dendritic peptide release. [Internet] [Doctoral dissertation]. University of Edinburgh; 2010. [cited 2021 Mar 01].
Available from: http://hdl.handle.net/1842/4420.
Council of Science Editors:
Monteiro OFdS. Mechanisms of dendritic peptide release. [Doctoral Dissertation]. University of Edinburgh; 2010. Available from: http://hdl.handle.net/1842/4420

Australian National University
23.
Flint, Sarah.
It's the chicken not the egg: visual attentional deficits in adults with dyslexia are not the result of a failure to learn to read
.
Degree: 2015, Australian National University
URL: http://hdl.handle.net/1885/110006
► The magnocellular deficit theory of dyslexia posits that many individuals with dyslexia demonstrate deficits in reading, visual attention and visual processing which can be attributed…
(more)
▼ The magnocellular deficit theory of dyslexia posits
that many individuals with dyslexia demonstrate deficits in
reading, visual attention and visual processing which can be
attributed to a functional failure of the magnocells in the
visual system, or general impairment in the dorsal visual
pathway. Research from the last 10 years has examined
magnocellular function in pre-readers, demonstrating that there
is a magnocellular deficit evident in pre-readers at familial
risk of dyslexia demonstrating a neurobiological underpinning to
dyslexia. The inclusion of illiterate adults as a comparison
group in lieu of pre-readers has garnered increasing interest in
recent years. The inclusion of illiterate adults as a test group
can provide strong evidence that any magnocellular deficits
demonstrated are not the result of reading experience or
orthographic familiarity. If a magnocellular deficit is
demonstrated between dyslexic readers and normal readers, but not
between illiterate adults and normal readers, the deficit cannot
be attributed to reading experience. The studies and chapters in
this dissertation set out to examine this. Illiterate adults
were to be recruited from the large illiterate population in
Papua New Guinea. However, as there was no linguistically and
culturally appropriate test of reading ability available in PNG
in order to determine literacy level in the PNG population. The
Flint Melanesian Reading Ability Assessment was developed to
address this need. The Flint Melanesian Reading Ability
Assessment examines the reading ability of adults in PNG in
either English or Tok Pisin. Furthermore, as the research was
being conducted cross-culturally, any possible cultural confounds
that would hinder cross-cultural comparisons needed to be
identified and strategies to overcome these identified.
Consequently, the role of culture on visual processing across
cultures was examined by comparing performance on visual search
tasks between undergraduate students from the University of PNG
and the Australian National University. It was found that
culture may influence visual processing. Section B examines the
role of magnocellular function in dyslexic adults compared to
normal, illiterate and semi-literate readers. Visual search,
coherent motion, and frequency doubling tasks were used to
investigate whether deficits in magnocellular processing were the
result of a failure to learn to read or the result of an
underlying biological deficit. Illiterate adults performed the
same as normal and semi-literate readers in visual search task
and all three groups performed better than the dyslexic readers
did. These findings indicate that there is a difference in the
visual attention of dyslexic readers. Likewise, the coherent
motion and frequency doubling tasks both demonstrated that the
…
Subjects/Keywords: Dyslexia;
Magnocellular Deficit Hypothesis;
Neurobiological;
Dorsal;
Coherent Motion;
Frequency Doubling Illusion;
Visual Search;
Cross-Cultural Psychology;
Papua New Guinea;
Australia;
Illiterate
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Flint, S. (2015). It's the chicken not the egg: visual attentional deficits in adults with dyslexia are not the result of a failure to learn to read
. (Thesis). Australian National University. Retrieved from http://hdl.handle.net/1885/110006
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Flint, Sarah. “It's the chicken not the egg: visual attentional deficits in adults with dyslexia are not the result of a failure to learn to read
.” 2015. Thesis, Australian National University. Accessed March 01, 2021.
http://hdl.handle.net/1885/110006.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Flint, Sarah. “It's the chicken not the egg: visual attentional deficits in adults with dyslexia are not the result of a failure to learn to read
.” 2015. Web. 01 Mar 2021.
Vancouver:
Flint S. It's the chicken not the egg: visual attentional deficits in adults with dyslexia are not the result of a failure to learn to read
. [Internet] [Thesis]. Australian National University; 2015. [cited 2021 Mar 01].
Available from: http://hdl.handle.net/1885/110006.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Flint S. It's the chicken not the egg: visual attentional deficits in adults with dyslexia are not the result of a failure to learn to read
. [Thesis]. Australian National University; 2015. Available from: http://hdl.handle.net/1885/110006
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
24.
Vahine, Théodora.
Traitements visuels précoces du langage écrit : études chez l'enfant et l'adulte jeune : Early visual processes in written language : studies in children and young adults.
Degree: Docteur es, Psychologie, 2017, Bordeaux
URL: http://www.theses.fr/2017BORD0857
► L’objectif de ce travail de thèse était d’étudier l’implication des systèmes visuels magnocellulaire et parvocellulaire dans le traitement de langage écrit, spécialement dans l’identification des…
(more)
▼ L’objectif de ce travail de thèse était d’étudier l’implication des systèmes visuels magnocellulaire et parvocellulaire dans le traitement de langage écrit, spécialement dans l’identification des mots. Quatre études expérimentales ont été réalisées afin de documenter le rôle respectif de ces deux systèmes pour différentes composantes de la structure du mot écrit, la lettre (Etude 1), la longueur du mot (Etude 2) et l’enveloppe du mot (Etude 3), ainsi que le voisinage orthographique (Etude 4). La dissociation des deux sous-systèmes visuels se fondait sur leurs caractéristiques fonctionnelles spécifiques : sensibilité aux fréquences spatiales basses et au contraste de luminance pour le système magnocellulaire ; sensibilité aux fréquences spatiales moyennes et élevées et au contraste chromatique pour le système parvocellulaire. Les participants étaient des adultes jeunes normolecteurs et des enfants de 10-11 ans, lecteurs novices, afin d’envisager l’implication de chaque système visuel à deux étapes de leur développement : maturité chez l’adulte jeune ; en cours de maturation chez l’enfant. Les résultats ont confirmé le rôle prépondérant des traitements parvocellulaires, ce qui corroborait le privilège accordé au traitement des lettres et traits des lettres dans la reconnaissance visuelle des mots. Le traitement de la longueur du mot s’est en revanche révélé être une dimension sélectivement magnocellulaire. L’ensemble des résultats est discuté dans le cadre de l’approche coarse-to-fine.
The main objective was to study the implication of the magnocellular and the parvocellular visual systems in written language processing, specifically in word identification. Four studies were carried out to document the respective roles of these two systems, for different components of the written word structure, the letter (Study 1), the word length (Study 2), the word shape (Study 3) and the orthographic neighborhood (Study 4). The dissociation of the two visual systems was based on their specific functional characteristics: sensitivity to low spatial frequencies and luminance contrast for the magnocellular system; and sensitivity to medium and high spatial frequencies and chromatic contrast for the parvocellular system. The participants were young adult normal readers and 10-11 years-old children, novice readers, in order to consider the involvement of each visual system at two stages of their development: mature in young adults while still maturing in the children. The results confirmed the prominent role of parvocellular processing, which was consistent with the privilege accorded to the processing of letters and letters features in visual word recognition. On the other hand, word length processing has been shown to be a selectively magnocellular dimension. All results are discussed in the framework of the coarse-to-fine approach.
Advisors/Committee Members: Foulin, Jean-Noël (thesis director), Delord, Sandrine (thesis director).
Subjects/Keywords: Psychophysique visuelle; Magnocellulaire; Parvocellulaire; Langage écrit; Identification de mot; Lettre; Visual psychophysics; Magnocellular; Parvocellular; Written language; Word identification; Letter
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Vahine, T. (2017). Traitements visuels précoces du langage écrit : études chez l'enfant et l'adulte jeune : Early visual processes in written language : studies in children and young adults. (Doctoral Dissertation). Bordeaux. Retrieved from http://www.theses.fr/2017BORD0857
Chicago Manual of Style (16th Edition):
Vahine, Théodora. “Traitements visuels précoces du langage écrit : études chez l'enfant et l'adulte jeune : Early visual processes in written language : studies in children and young adults.” 2017. Doctoral Dissertation, Bordeaux. Accessed March 01, 2021.
http://www.theses.fr/2017BORD0857.
MLA Handbook (7th Edition):
Vahine, Théodora. “Traitements visuels précoces du langage écrit : études chez l'enfant et l'adulte jeune : Early visual processes in written language : studies in children and young adults.” 2017. Web. 01 Mar 2021.
Vancouver:
Vahine T. Traitements visuels précoces du langage écrit : études chez l'enfant et l'adulte jeune : Early visual processes in written language : studies in children and young adults. [Internet] [Doctoral dissertation]. Bordeaux; 2017. [cited 2021 Mar 01].
Available from: http://www.theses.fr/2017BORD0857.
Council of Science Editors:
Vahine T. Traitements visuels précoces du langage écrit : études chez l'enfant et l'adulte jeune : Early visual processes in written language : studies in children and young adults. [Doctoral Dissertation]. Bordeaux; 2017. Available from: http://www.theses.fr/2017BORD0857

University of Georgia
25.
Guenther, Benjamin Aaron.
Using the steady/pulsed-pedestal paradigm to study visual attention.
Degree: 2014, University of Georgia
URL: http://hdl.handle.net/10724/27145
► Researchers continue to explore the relationship between different attention phenomenon and the sensory nature of the stimuli; however, this relationship is still not well understood.…
(more)
▼ Researchers continue to explore the relationship between different attention phenomenon and the sensory nature of the stimuli; however, this relationship is still not well understood. The steady- and pulsed-pedestal paradigm (S/PP paradigm)
is a simple and flexible stimulus manipulation influencing relative processing along transient and sustained channels. The purposes of the present experiments were to first, evaluate the effectiveness of this paradigm when simple reaction time (RT) was
the dependent measure, and second to further explore the relationship between transient and sustained channel activity and two common attention effects, the object advantage and inhibition of return (IOR). The S/PP paradigm produced a consistent pattern
of effects across both attention paradigms with pulsed-pedestal conditions having a greater influence on RTs to invalidly cued targets. This resulted in an increased validity effect in an object-based attention experiment and decreased IOR magnitudes.
Results indicated, first, the S/PP paradigm can be effectively used with RT as a dependent measure. And secondly, the S/PP paradigm (a task-irrelevant manipulation) has a different influence on attention than previously used task-relevant manipulations.
Additionally, future theories and accounts for IOR and the object advantage need to be able to address the sensory influences revealed through manipulations of relative processing of transient and sustained channels.
Subjects/Keywords: Visuospatial Attention; Inhibition of Return; Object Advantage; Magnocellular and Parvocellular Visual Pathways; Transient and Sustained Channels
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Guenther, B. A. (2014). Using the steady/pulsed-pedestal paradigm to study visual attention. (Thesis). University of Georgia. Retrieved from http://hdl.handle.net/10724/27145
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Guenther, Benjamin Aaron. “Using the steady/pulsed-pedestal paradigm to study visual attention.” 2014. Thesis, University of Georgia. Accessed March 01, 2021.
http://hdl.handle.net/10724/27145.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Guenther, Benjamin Aaron. “Using the steady/pulsed-pedestal paradigm to study visual attention.” 2014. Web. 01 Mar 2021.
Vancouver:
Guenther BA. Using the steady/pulsed-pedestal paradigm to study visual attention. [Internet] [Thesis]. University of Georgia; 2014. [cited 2021 Mar 01].
Available from: http://hdl.handle.net/10724/27145.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Guenther BA. Using the steady/pulsed-pedestal paradigm to study visual attention. [Thesis]. University of Georgia; 2014. Available from: http://hdl.handle.net/10724/27145
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Saskatchewan
26.
Wang, David Daoyi.
Expression and targeting of voltage-gated Ca2+ channels in neuroendocrine cells and pituicytes.
Degree: 2010, University of Saskatchewan
URL: http://hdl.handle.net/10388/etd-12222010-173315
► Magnocellular neurosecretory cells (MNCs) are neuroendocrine cells with somata located in the hypothalamus and nerve terminals in the posterior pituitary. They receive neuronal inputs from…
(more)
▼ Magnocellular neurosecretory cells (MNCs) are neuroendocrine cells with somata located in the hypothalamus and nerve terminals in the posterior pituitary. They receive neuronal inputs from the brain and release vasopressin and oxytocin into the blood to regulate many important functions such as water balance, lactation, and parturition. The process of hormone release depends on Ca2+ influx mediated by voltage-gated Ca2+ channels (VGCCs) on the plasma membranes of neuroendocrine cells. To better understand the cellular and molecular components that are involved in regulating secretory vesicle exocytosis, this thesis work was conducted to investigate the expression and function of different subtypes of VGCCs in MNCs and pituicytes (the glial cells surrounding MNC nerve terminals).
Molecular biology, immunohistochemistry and cellular biology were used to detect expression and alternative splicing of different VGCC subtypes in MNCs, neurons, and pituicytes. First, the presence of CaV2.2 and CaV2.3 channels were detected on the pituicytes in situ. When the pituicytes were isolated and cultured for 14 days, more VGCC subtypes were expressed including CaV1.2 channels. Regulation of VGCC expression was measured in normal and dehydrated rats, and CaV1.2 channels were found to be selectively up-regulated in pituicytes after 24 hours of dehydration.
Second, two splice variants of CaV2.1 channels (CaV2.1Ä1 and Ä2) that lack a large portion of the synprint (synaptic protein interaction) site were detected in the rat brain. To determine whether the splice variants were expressed in MNCs, we did immunocytochemistry using two antibodies (the selective and the inclusive antibody) that recognized the carboxyl-terminus of channels and the synprint site, respectively, in different cell types. We found that vasopressin MNCs, but not the oxytocin MNCs, and one type of endocrine cell (the melanotropes of the pituitary gland) expressed the synprint site deleted variants, whereas the hippocampal neurons mainly expressed the full-length isoform. The splice variants were properly distributed on the plasma membrane of the somata and nerve terminals of the MNCs, suggesting the synprint site is not essential for CaV2.1 channel targeting into the nerve terminals of neuroendocrine cells.
Third, expression and distribution of CaV2.2 channels were studied in the MNCs. All CaV2.2 isoforms we detected contained the full-length synprint site. To test the importance of the CASK/Mint1 binding site for CaV2.2 channel targeting, we over-expressed a peptide that inhibits the interaction between CaV2.2 channels and CASK/Mint1 in differentiated PC12 cells (a neuroendocrine cell line). We found that the distribution of CaV2.2 channels in the growth cones of PC12 cells were significantly decreased, suggesting that the CASK/Mint1 interaction is important for CaV2.2 channel targeting into the neuroendocrine terminals.
In conclusion, these results provide insights of VGCC expression in neuroendocrine cells, and also give rise to a better understanding of…
Advisors/Committee Members: Fisher, Thomas, West, Nigel, Desautels, Michel, Gray, Jack, Mulligan, Sean, Tse, Amy.
Subjects/Keywords: Ion channels; Alternative splicing; Synprint site; CaV2 channels; Magnocellular neurosecretory cells
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Wang, D. D. (2010). Expression and targeting of voltage-gated Ca2+ channels in neuroendocrine cells and pituicytes. (Thesis). University of Saskatchewan. Retrieved from http://hdl.handle.net/10388/etd-12222010-173315
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Wang, David Daoyi. “Expression and targeting of voltage-gated Ca2+ channels in neuroendocrine cells and pituicytes.” 2010. Thesis, University of Saskatchewan. Accessed March 01, 2021.
http://hdl.handle.net/10388/etd-12222010-173315.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Wang, David Daoyi. “Expression and targeting of voltage-gated Ca2+ channels in neuroendocrine cells and pituicytes.” 2010. Web. 01 Mar 2021.
Vancouver:
Wang DD. Expression and targeting of voltage-gated Ca2+ channels in neuroendocrine cells and pituicytes. [Internet] [Thesis]. University of Saskatchewan; 2010. [cited 2021 Mar 01].
Available from: http://hdl.handle.net/10388/etd-12222010-173315.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Wang DD. Expression and targeting of voltage-gated Ca2+ channels in neuroendocrine cells and pituicytes. [Thesis]. University of Saskatchewan; 2010. Available from: http://hdl.handle.net/10388/etd-12222010-173315
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Queensland University of Technology
27.
Kuo, Hui-Ying.
Comparison of temporal processing and motion perception in emmetropes and myopes.
Degree: 2009, Queensland University of Technology
URL: https://eprints.qut.edu.au/31905/
► While spatial determinants of emmetropization have been examined extensively in animal models and spatial processing of human myopes has also been studied, there have been…
(more)
▼ While spatial determinants of emmetropization have been examined extensively in animal models and spatial processing of human myopes has also been studied, there have been few studies investigating temporal aspects of emmetropization and temporal processing in human myopia. The influence of temporal light modulation on eye growth and refractive compensation has been observed in animal models and there is evidence of temporal visual processing deficits in individuals with high myopia or other pathologies. Given this, the aims of this work were to examine the relationships between myopia (i.e. degree of myopia and progression status) and temporal visual performance and to consider any temporal processing deficits in terms of the parallel retinocortical pathways.
Three psychophysical studies investigating temporal processing performance were conducted in young adult myopes and non-myopes: (1) backward visual masking, (2) dot motion perception and (3) phantom contour. For each experiment there were approximately 30 young emmetropes, 30 low myopes (myopia less than 5 D) and 30 high myopes (5 to 12 D). In the backward visual masking experiment, myopes were also classified according to their progression status (30 stable myopes and 30 progressing myopes).
The first study was based on the observation that the visibility of a target is reduced by a second target, termed the mask, presented quickly after the first target. Myopes were more affected by the mask when the task was biased towards the magnocellular pathway; myopes had a 25% mean reduction in performance compared with emmetropes. However, there was no difference in the effect of the mask when the task was biased towards the parvocellular system. For all test conditions, there was no significant correlation between backward visual masking task performance and either the degree of myopia or myopia progression status.
The dot motion perception study measured detection thresholds for the minimum displacement of moving dots, the maximum displacement of moving dots and degree of motion coherence required to correctly determine the direction of motion. The visual processing of these tasks is dominated by the magnocellular pathway. Compared with emmetropes, high myopes had reduced ability to detect the minimum displacement of moving dots for stimuli presented at the fovea (20% higher mean threshold) and possibly at the inferior nasal retina. The minimum displacement threshold was significantly and positively correlated to myopia magnitude and axial length, and significantly and negatively correlated with retinal thickness for the inferior nasal retina. The performance of emmetropes and myopes for all the other dot motion perception tasks were similar.
In the phantom contour study, the highest temporal frequency of the flickering phantom pattern at which the contour was visible was determined. Myopes had significantly lower flicker detection limits (21.8 ± 7.1 Hz) than emmetropes (25.6 ± 8.8 Hz) for tasks biased towards the magnocellular pathway for both high…
Subjects/Keywords: backward visual masking, Dmax, Dmin, dot motion perception, human psychophysics, magnocellular deficit, minimum displacement detection, motion coherence, myopia, myopia progression, phantom contour, refractive error, retinal thickness, visual pathways; visual temporal processing
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Kuo, H. (2009). Comparison of temporal processing and motion perception in emmetropes and myopes. (Thesis). Queensland University of Technology. Retrieved from https://eprints.qut.edu.au/31905/
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Kuo, Hui-Ying. “Comparison of temporal processing and motion perception in emmetropes and myopes.” 2009. Thesis, Queensland University of Technology. Accessed March 01, 2021.
https://eprints.qut.edu.au/31905/.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Kuo, Hui-Ying. “Comparison of temporal processing and motion perception in emmetropes and myopes.” 2009. Web. 01 Mar 2021.
Vancouver:
Kuo H. Comparison of temporal processing and motion perception in emmetropes and myopes. [Internet] [Thesis]. Queensland University of Technology; 2009. [cited 2021 Mar 01].
Available from: https://eprints.qut.edu.au/31905/.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Kuo H. Comparison of temporal processing and motion perception in emmetropes and myopes. [Thesis]. Queensland University of Technology; 2009. Available from: https://eprints.qut.edu.au/31905/
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Université de Montréal
28.
Tremblay, Emmanuel.
Développement des voies visuelles primaires au cours de la première année de vie chez le bébé prématuré et le béné né à terme : une étude en électrophysiologie à haute densité.
Degree: 2009, Université de Montréal
URL: http://hdl.handle.net/1866/6361
Subjects/Keywords: Vision; Visual maturation; Magnocellulaire; Magnocellular; Parvocellulaire; Parvocellular; Topographie; Brain topography; Potentiel évoqué; Visual evoked potentials; Développement; Brain development; Enfant; Infants; Fréquences spatiales; Spatial frequency; Contraste; Contrast; Aires extrastriées
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APA (6th Edition):
Tremblay, E. (2009). Développement des voies visuelles primaires au cours de la première année de vie chez le bébé prématuré et le béné né à terme : une étude en électrophysiologie à haute densité. (Thesis). Université de Montréal. Retrieved from http://hdl.handle.net/1866/6361
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Tremblay, Emmanuel. “Développement des voies visuelles primaires au cours de la première année de vie chez le bébé prématuré et le béné né à terme : une étude en électrophysiologie à haute densité.” 2009. Thesis, Université de Montréal. Accessed March 01, 2021.
http://hdl.handle.net/1866/6361.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Tremblay, Emmanuel. “Développement des voies visuelles primaires au cours de la première année de vie chez le bébé prématuré et le béné né à terme : une étude en électrophysiologie à haute densité.” 2009. Web. 01 Mar 2021.
Vancouver:
Tremblay E. Développement des voies visuelles primaires au cours de la première année de vie chez le bébé prématuré et le béné né à terme : une étude en électrophysiologie à haute densité. [Internet] [Thesis]. Université de Montréal; 2009. [cited 2021 Mar 01].
Available from: http://hdl.handle.net/1866/6361.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Tremblay E. Développement des voies visuelles primaires au cours de la première année de vie chez le bébé prématuré et le béné né à terme : une étude en électrophysiologie à haute densité. [Thesis]. Université de Montréal; 2009. Available from: http://hdl.handle.net/1866/6361
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
.