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Boston University
1.
Maier, Mihaela.
Magnetization transfer effect on T1 relaxometry on 1.5T vs. 3T.
Degree: MS, Bioimaging, 2017, Boston University
URL: http://hdl.handle.net/2144/26732
► PURPOSE: To assess the variability of incidental magnetization transfer effect (MT) by the number of slices and the magnetic field strength. METHODS: Various magnetic resonance…
(more)
▼ PURPOSE: To assess the variability of incidental magnetization transfer effect (MT) by the number of slices and the magnetic field strength.
METHODS: Various magnetic resonance images (MRI) were obtained with a phantom containing a series of solutions of gadolinium (Gd) and sucrose in distilled water, agarose gel and two vials with olive oil and distilled water. A diffusion weighted image (DWI) sequence was acquired to determine diffusion coefficient for each component of the phantom. Several inversion recovery (IR) sequences having different TI values were run for single-slice and used to calculate T1 relaxation time with maximum precision and minimizing magnetization transfer effect. The T1 relaxation value resulting from processing IR sequences was used as reference value. The mixed-TSE sequences were used to calculate T1, T2 and PD values and to assess MT effect for single-slice as for multi-slice acquisition. All the DICOM MR images were processed using various algorithms programmed in Mathcad (version 2001i, PTC Needham, MA) by Dr. Hernan Jara. According with the potential of each sequences the programs generated the qMRI maps and values of T1, T2, PD were obtained for all the components of the phantom. Values resulted from Mathcad calculation were used for analysis. All the acquisitions, calculations and measurements were performed for 1.5T and 3T field strength.
Subjects/Keywords: Medical imaging; Relaxometry; Magnetization transfer
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APA (6th Edition):
Maier, M. (2017). Magnetization transfer effect on T1 relaxometry on 1.5T vs. 3T. (Masters Thesis). Boston University. Retrieved from http://hdl.handle.net/2144/26732
Chicago Manual of Style (16th Edition):
Maier, Mihaela. “Magnetization transfer effect on T1 relaxometry on 1.5T vs. 3T.” 2017. Masters Thesis, Boston University. Accessed January 16, 2021.
http://hdl.handle.net/2144/26732.
MLA Handbook (7th Edition):
Maier, Mihaela. “Magnetization transfer effect on T1 relaxometry on 1.5T vs. 3T.” 2017. Web. 16 Jan 2021.
Vancouver:
Maier M. Magnetization transfer effect on T1 relaxometry on 1.5T vs. 3T. [Internet] [Masters thesis]. Boston University; 2017. [cited 2021 Jan 16].
Available from: http://hdl.handle.net/2144/26732.
Council of Science Editors:
Maier M. Magnetization transfer effect on T1 relaxometry on 1.5T vs. 3T. [Masters Thesis]. Boston University; 2017. Available from: http://hdl.handle.net/2144/26732

Delft University of Technology
2.
Vedula, Mano (author).
Myelin Imaging in Brain using Inhomogeneous Magnetization Transfer(ihMT) at 3T and 7T.
Degree: 2020, Delft University of Technology
URL: http://resolver.tudelft.nl/uuid:ed118642-7370-471f-9045-948f656887e3
► Demyelination is described as loss of myelin sheath in neurons which could lead to disruption in signal transmission in nervous system. Inhomogeneous Magnetization Transfer(ihMT) is…
(more)
▼ Demyelination is described as loss of myelin sheath in neurons which could lead to disruption in signal transmission in nervous system. Inhomogeneous Magnetization Transfer(ihMT) is a novel MRI technique used to image myelin. It uses the dipolar coupling between methyl chains in lipid layers of myelin to acquire myelin specific information. In this study, we investigated the feasibility of ihMT at 7T. Based on phantom experiments and Bloch simulations, the influence of off-resonance frequency Δ, RF field strength B1 and RF pulse proprieties on ihMTR are studied and optimized. For in-vivo imaging, the experiments are conducted on healthy volunteers. Since B1 inhomogeneties are prevalent at higher fields, an optimized protocol is devised to achieve maximum ihMT effect at 7T. A comparison of 3T and 7T for the off-resonance frequency, RF field strength and pulse proprieties is presented to emphasize the impact of parameters at both the field strengths.
Electrical Engineering | Signals and Systems
Advisors/Committee Members: Remis, Rob (mentor), Ercan, Ece (graduation committee), Staring, Marius (graduation committee), Delft University of Technology (degree granting institution).
Subjects/Keywords: Myelin imaging; MRI; Inhomogeneous Magnetization Transfer
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APA (6th Edition):
Vedula, M. (. (2020). Myelin Imaging in Brain using Inhomogeneous Magnetization Transfer(ihMT) at 3T and 7T. (Masters Thesis). Delft University of Technology. Retrieved from http://resolver.tudelft.nl/uuid:ed118642-7370-471f-9045-948f656887e3
Chicago Manual of Style (16th Edition):
Vedula, Mano (author). “Myelin Imaging in Brain using Inhomogeneous Magnetization Transfer(ihMT) at 3T and 7T.” 2020. Masters Thesis, Delft University of Technology. Accessed January 16, 2021.
http://resolver.tudelft.nl/uuid:ed118642-7370-471f-9045-948f656887e3.
MLA Handbook (7th Edition):
Vedula, Mano (author). “Myelin Imaging in Brain using Inhomogeneous Magnetization Transfer(ihMT) at 3T and 7T.” 2020. Web. 16 Jan 2021.
Vancouver:
Vedula M(. Myelin Imaging in Brain using Inhomogeneous Magnetization Transfer(ihMT) at 3T and 7T. [Internet] [Masters thesis]. Delft University of Technology; 2020. [cited 2021 Jan 16].
Available from: http://resolver.tudelft.nl/uuid:ed118642-7370-471f-9045-948f656887e3.
Council of Science Editors:
Vedula M(. Myelin Imaging in Brain using Inhomogeneous Magnetization Transfer(ihMT) at 3T and 7T. [Masters Thesis]. Delft University of Technology; 2020. Available from: http://resolver.tudelft.nl/uuid:ed118642-7370-471f-9045-948f656887e3

Louisiana State University
3.
Schurr, Ryan Nicholas.
Z-Spectral Modeling for Magnetization Transfer Ratio Asymmetry Calculations in Chemical Exchange Saturation Transfer MRI at 3 Tesla.
Degree: MS, Physical Sciences and Mathematics, 2015, Louisiana State University
URL: etd-06182015-155915
;
https://digitalcommons.lsu.edu/gradschool_theses/2661
► Chemical exchange saturation transfer (CEST) and magnetization transfer (MT) are types of magnetic resonance imaging (MRI) experiments in which contrast is based on the transfer…
(more)
▼ Chemical exchange saturation transfer (CEST) and magnetization transfer (MT) are types of magnetic resonance imaging (MRI) experiments in which contrast is based on the transfer of magnetization from selectively saturated solute or macromolecular protons to bulk water protons. These processes offer insight into the chemical composition of tissue and are quantified by the asymmetry of the magnetization transfer ratio (MTRasym). This study was to develop a Z-spectral curve fitting procedure based on the underlying physics of CEST-MRI from which MTRasym values can be calculated and applied to distinguish healthy tissue from cancer. Z-spectra were collected from CEST-MR images of a phantom. The data were fit to both the proposed model which separately fits the upfield and downfield regions of the Z-spectra, and two polynomial models from literature. A preferred model was identified using the small sample bias-corrected Akaike’s Information Criterion (AICc). Z-spectra were collected from CEST-MR images of prostate cancer patients and fit with the same models; the preferred model was selected using the AICc. CEST-MR images of bladder cancer patients were acquired and the Z-spectra were fit with the preferred model identified from the phantom images. MTRasym was calculated at frequency offsets of 3.5 ppm and 2.0 ppm to determine if these quantities were capable of distinguishing normal bladder wall (NBW) from bladder cancer. The proposed fitting model with a 5th order polynomial for the downfield region was the preferred curve fitting model by the AICc model selection procedure for the phantom while a 6th order polynomial was preferred for the prostate cancer Z-spectra. MTRasym(2.0 ppm) values calculated from the bladder cancer Z-spectra did not differ significantly between the NBW and tumor regions. A statistically significant difference existed between the NBW and tumor regions for the MTRasym(3.5 ppm) values (p < 0.001). The proposed model was preferred to the polynomial models from literature based on the AICc metric. Application of the technique to patient images showed the potential to distinguish NBW from bladder cancer based on the statistically significant MTRasym(3.5 ppm) values in these regions.
Subjects/Keywords: MRI; CEST; magnetization transfer; quantitative imaging
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APA (6th Edition):
Schurr, R. N. (2015). Z-Spectral Modeling for Magnetization Transfer Ratio Asymmetry Calculations in Chemical Exchange Saturation Transfer MRI at 3 Tesla. (Masters Thesis). Louisiana State University. Retrieved from etd-06182015-155915 ; https://digitalcommons.lsu.edu/gradschool_theses/2661
Chicago Manual of Style (16th Edition):
Schurr, Ryan Nicholas. “Z-Spectral Modeling for Magnetization Transfer Ratio Asymmetry Calculations in Chemical Exchange Saturation Transfer MRI at 3 Tesla.” 2015. Masters Thesis, Louisiana State University. Accessed January 16, 2021.
etd-06182015-155915 ; https://digitalcommons.lsu.edu/gradschool_theses/2661.
MLA Handbook (7th Edition):
Schurr, Ryan Nicholas. “Z-Spectral Modeling for Magnetization Transfer Ratio Asymmetry Calculations in Chemical Exchange Saturation Transfer MRI at 3 Tesla.” 2015. Web. 16 Jan 2021.
Vancouver:
Schurr RN. Z-Spectral Modeling for Magnetization Transfer Ratio Asymmetry Calculations in Chemical Exchange Saturation Transfer MRI at 3 Tesla. [Internet] [Masters thesis]. Louisiana State University; 2015. [cited 2021 Jan 16].
Available from: etd-06182015-155915 ; https://digitalcommons.lsu.edu/gradschool_theses/2661.
Council of Science Editors:
Schurr RN. Z-Spectral Modeling for Magnetization Transfer Ratio Asymmetry Calculations in Chemical Exchange Saturation Transfer MRI at 3 Tesla. [Masters Thesis]. Louisiana State University; 2015. Available from: etd-06182015-155915 ; https://digitalcommons.lsu.edu/gradschool_theses/2661

University of Toronto
4.
Desmond, Kimberly Lara.
Endogenous Chemical Exchange Saturation Transfer: Quantitative Modelling and Application in Cancer.
Degree: PhD, 2014, University of Toronto
URL: http://hdl.handle.net/1807/73783
► This work describes the origins of the contrast mechanism chemical exchange saturation transfer (CEST) and methods for proton magnetic resonance imaging (MRI), with application in…
(more)
▼ This work describes the origins of the contrast mechanism chemical exchange saturation
transfer (CEST) and methods for proton magnetic resonance imaging (MRI), with application in cancer. It focuses on endogenous techniques, which do not require the injection of a contrast agent, and the experimental and analytic techniques which allow quantitative metrics to be obtained. The theory behind CEST is presented, and it is modelled using a three pool system of Bloch equations which are a function of
magnetization relaxation parameters, CEST pool concentration, and hydrogen exchange rate constant. A platform is created for optimization and parameter fitting, which is used to obtain parameter values and for pulse sequence experimental design. The contribution of semi-solid macromolecules to the CEST spectrum is determined, and evidence given that the CEST parameters (in particular, the exchange rate constant) can be obtained independently of this additional pool. It is shown that there is a linear relationship between the log of the exchange rate constant and pH. CEST spectra are obtained in cancer xenografts in mice, exhibiting features from amide, amine and aliphatic protons as well as from
magnetization transfer. Semi-quantitative CEST parameter maps are derived, showing the distribution of CEST features in tumours and in contrast with the surrounding normal-appearing muscle. Several exploratory experiments are performed in protein-containing phantoms and cell pellets in order to validate the origins of CEST spectra and their behaviour in conditions of changing pH and temperature. Cell pellet experiments support the hypothesis that CEST is sensitive primarily to intracellular conditions, and furthermore that the cell nucleus is a concentrated source of CEST-contributing proteins. These validation experiments are supportive of the assumptions made in the next section, in which a ratiometric method of determining intracellular pH from CEST spectra is proposed and proof-of-concept experiments are performed. Ultimately, the work contained herein supports the hypothesis that the endogenous CEST experiments provide new information not obtainable from other MRI experiments, leading to quantitative absolute intracellular pH mapping. This has potential for predicting the effectiveness of treatment regimens based upon the relationship between intracellular pH and drug uptake, establishing regions of tumour which are actively proliferating or which may be resistant to therapy.
Advisors/Committee Members: Stanisz, Greg J, Medical Biophysics.
Subjects/Keywords: CEST; chemical exchange saturation transfer; magnetization transfer; MRI; pH; 0786
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APA ·
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APA (6th Edition):
Desmond, K. L. (2014). Endogenous Chemical Exchange Saturation Transfer: Quantitative Modelling and Application in Cancer. (Doctoral Dissertation). University of Toronto. Retrieved from http://hdl.handle.net/1807/73783
Chicago Manual of Style (16th Edition):
Desmond, Kimberly Lara. “Endogenous Chemical Exchange Saturation Transfer: Quantitative Modelling and Application in Cancer.” 2014. Doctoral Dissertation, University of Toronto. Accessed January 16, 2021.
http://hdl.handle.net/1807/73783.
MLA Handbook (7th Edition):
Desmond, Kimberly Lara. “Endogenous Chemical Exchange Saturation Transfer: Quantitative Modelling and Application in Cancer.” 2014. Web. 16 Jan 2021.
Vancouver:
Desmond KL. Endogenous Chemical Exchange Saturation Transfer: Quantitative Modelling and Application in Cancer. [Internet] [Doctoral dissertation]. University of Toronto; 2014. [cited 2021 Jan 16].
Available from: http://hdl.handle.net/1807/73783.
Council of Science Editors:
Desmond KL. Endogenous Chemical Exchange Saturation Transfer: Quantitative Modelling and Application in Cancer. [Doctoral Dissertation]. University of Toronto; 2014. Available from: http://hdl.handle.net/1807/73783

Universiteit Utrecht
5.
Oorschot, J.W.M. van.
Endogenous assessment of myocardial fibrosis with quantitative MRI.
Degree: 2016, Universiteit Utrecht
URL: http://dspace.library.uu.nl:8080/handle/1874/328798
► In this thesis, we have studied the use of quantitative MR contrast mechanisms, that could potentially be used for endogenous detection of myocardial fibrosis in…
(more)
▼ In this thesis, we have studied the use of quantitative MR contrast mechanisms, that could potentially be used for endogenous detection of myocardial fibrosis in the clinic. we have mainly focused on T2*, T1ρ MRI and
Magnetization Transfer Imaging, and found that T1ρ -mapping, and
Magnetization Transfer imaging are most promising. We found a significantly higher T1ρ-relaxation time in myocardial infarct tissue, compared to healthy remote tissue, both in a porcine animal model and chronic infarct patients. A comparison with LGE as gold standard for infarct detection, showed that native T1ρ –maps can be used to locate the myocardial scar area. For diffuse myocardial fibrosis, we have shown that T1ρ relaxation times correlate with the amount of fibrosis, determined by histology, and with extracellular volume fraction, measured in vivo. The results of native T1 –mapping in DCM patients did not indicate a significant relation with extracellular volume fraction in patients. Measurements of
magnetization transfer in an animal model showed a decrease in
magnetization transfer ratio in the infarct area, and the addition of an MT pulse in front of a T1ρ-mapping experiment resulted in a significantly higher T1ρ-relaxation time.
For infarct detection with T1ρ –mapping the main advantage compared to gold standard LGE imaging is that a contrast agent is no longer required. As a first step towards clinical applications, this technique could be used as an alternative in patients that are unable to receive a gadolinium based contrast agent, such as patients with severe renal failure. Also for diffuse fibrosis, T1ρ –mapping can be used as an alternative to the gadolinium based ECV-mapping. When the sensitivity of the technique is significantly increased, it could be considered as an alternative for LGE and ECV-mapping in clinical practice for all patients.
Advisors/Committee Members: Luijten, P.R., Leiner, T., Zwanenburg, J.J.M..
Subjects/Keywords: MRI; Cardiac; Heart; Endogenous; T1rho; Magnetization Transfer; Contrast agent; Native
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APA ·
Chicago ·
MLA ·
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APA (6th Edition):
Oorschot, J. W. M. v. (2016). Endogenous assessment of myocardial fibrosis with quantitative MRI. (Doctoral Dissertation). Universiteit Utrecht. Retrieved from http://dspace.library.uu.nl:8080/handle/1874/328798
Chicago Manual of Style (16th Edition):
Oorschot, J W M van. “Endogenous assessment of myocardial fibrosis with quantitative MRI.” 2016. Doctoral Dissertation, Universiteit Utrecht. Accessed January 16, 2021.
http://dspace.library.uu.nl:8080/handle/1874/328798.
MLA Handbook (7th Edition):
Oorschot, J W M van. “Endogenous assessment of myocardial fibrosis with quantitative MRI.” 2016. Web. 16 Jan 2021.
Vancouver:
Oorschot JWMv. Endogenous assessment of myocardial fibrosis with quantitative MRI. [Internet] [Doctoral dissertation]. Universiteit Utrecht; 2016. [cited 2021 Jan 16].
Available from: http://dspace.library.uu.nl:8080/handle/1874/328798.
Council of Science Editors:
Oorschot JWMv. Endogenous assessment of myocardial fibrosis with quantitative MRI. [Doctoral Dissertation]. Universiteit Utrecht; 2016. Available from: http://dspace.library.uu.nl:8080/handle/1874/328798

Vanderbilt University
6.
Janve, Vaibhav Anil.
Myelin sensitivity in quantitative magnetization transfer and diffusion tensor imaging in an animal model of multiple sclerosis.
Degree: PhD, Physics, 2015, Vanderbilt University
URL: http://hdl.handle.net/1803/11234
► Conventional MRI is sensitive to detect brain abnormalities non-invasively through excellent contrast generated by variation in relaxation times and water proton density. However, conventional MRI…
(more)
▼ Conventional MRI is sensitive to detect brain abnormalities non-invasively through excellent contrast generated by variation in relaxation times and water proton density. However, conventional MRI lacks the specificity and quantitation to specific pathologies and tissue components such as myelin. Myelin is the major constituent of white matter ─an insulating macromolecular sleeve wrapped around axons of brain cells. Loss of white matter, specifically myelin leads to severe motor and cognitive deficits in diseases such as multiple sclerosis. Advanced quantitative MRI methods such as quantitative
magnetization transfer (qMT) and diffusion tensor imaging (DTI) have emerged as putative biomarkers that improve sensitivity, specificity and provide quantitative metrics to measure myelin. qMT and DTI are model based quantitative techniques, which provide sub-voxel information of the underlying tissue architecture. qMT is sensitive to the tissue macromolecular content, whereas DTI is sensitive to tissue microstructure. Pool size ratio (PSR, a qMT parameter) and radial diffusivity (RD, a DTI parameter) provide an indirect quantitative measure of myelin. However, their relative sensitivities and specificities to myelin are unclear. qMT and DTI are based on different physical principles and may provide complementary information. While histology is the gold standard for myelin quantification, it can only be performed postmortem or through invasive biopsies. Thus, systematic quantitative MRI and histological validation studies are essential to determine the specific sensitivities of non-invasive quantitative metrics. Although, limited data is available on such studies due to their tedious, time intensive and complex nature. My thesis work addresses this gap by performing quantitative MRI and histological validation on a relatively new animal model of multiple sclerosis (MS), which recapitulates the inflammatory and non-inflammatory demyelinating phases seen in patients. The animal model was characterized using structural MRI, qMRI and histological methods. To enable quantitative comparisons amongst MRI and histological parameters, detailed processing protocol were designed and implemented including 3D qMT and DTI protocols and histological pipeline. In vivo and ex vivo studies were performed and qMT and DTI metrics were correlated with histology and among each other to determine their specific sensitivities. Furthermore, in an attempt to translate the animal work to clinical settings, a fast qMT sequence with GRASE readout was tested on human scanners. In conclusion, we found that PSR, and RD are sensitive to histological myelin content with PSR having the strongest correlation.
Advisors/Committee Members: Adam W. Anderson (committee member), David J. Ernst (committee member), Mark D. Does (committee member), John C. Gore (committee member), Daniel F. Gochberg (Committee Chair).
Subjects/Keywords: MRI; magnetization transfer; diffusion; multiple sclerosis; qMT; DTI; quantitative
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APA (6th Edition):
Janve, V. A. (2015). Myelin sensitivity in quantitative magnetization transfer and diffusion tensor imaging in an animal model of multiple sclerosis. (Doctoral Dissertation). Vanderbilt University. Retrieved from http://hdl.handle.net/1803/11234
Chicago Manual of Style (16th Edition):
Janve, Vaibhav Anil. “Myelin sensitivity in quantitative magnetization transfer and diffusion tensor imaging in an animal model of multiple sclerosis.” 2015. Doctoral Dissertation, Vanderbilt University. Accessed January 16, 2021.
http://hdl.handle.net/1803/11234.
MLA Handbook (7th Edition):
Janve, Vaibhav Anil. “Myelin sensitivity in quantitative magnetization transfer and diffusion tensor imaging in an animal model of multiple sclerosis.” 2015. Web. 16 Jan 2021.
Vancouver:
Janve VA. Myelin sensitivity in quantitative magnetization transfer and diffusion tensor imaging in an animal model of multiple sclerosis. [Internet] [Doctoral dissertation]. Vanderbilt University; 2015. [cited 2021 Jan 16].
Available from: http://hdl.handle.net/1803/11234.
Council of Science Editors:
Janve VA. Myelin sensitivity in quantitative magnetization transfer and diffusion tensor imaging in an animal model of multiple sclerosis. [Doctoral Dissertation]. Vanderbilt University; 2015. Available from: http://hdl.handle.net/1803/11234

Vanderbilt University
7.
West, Kathryn Louise.
Development and Evaluation of Relaxation-Based Measures of Myelin Content and Microstructure in Rodent Brains.
Degree: PhD, Biomedical Engineering, 2016, Vanderbilt University
URL: http://hdl.handle.net/1803/14525
► Advanced neuroimaging techniques provide the possibility to non-invasively understand and monitor white matter during development and disease. While data from quantitative MRI techniques, such as…
(more)
▼ Advanced neuroimaging techniques provide the possibility to non-invasively understand and monitor white matter during development and disease. While data from quantitative MRI techniques, such as multiexponential T2 (MET2) and quantitative
magnetization transfer (qMT), correlate with myelin content, neither provide an absolute measure of the myelin volume fraction (MVF). Additionally, in preclinical studies, despite time-intensity and small tissue samples, histology remains the gold standard for quantitatively assessing changes in myelin content and white matter microstructural properties, such as myelin thickness and the g-ratio (ratio of axon radius to myelinated fiber radius). Therefore, the work in this dissertation first established and validated methods for MVF imaging from MET2 and qMT against quantitative electron microscopy. We show strong agreement in adult, control mice along with three mouse models of white matter disease. Next, we applied MVF imaging in mice during normal development and observe good agreement between MET2 and qMT and with expected myelin development. To further investigate specific changes in myelin microstructure, recent methods proposed measuring the g-ratio from MRI (gMRI). We revised the model and displayed with quantitative histology that gMRI provides an axon-area-weighted g-ratio. Calculating gMRI requires an accurate measure of MVF; thus, we utilize our MVF imaging techniques to measure gMRI in mouse brain and detect changes in g-ratio with disease in agreement with quantitative histology. In short, we develop and validate measures of MVF and g-ratio from MRI which have the potential to non-invasively provide more specific and thorough assessment of white matter not obtainable with currently used methods.
Advisors/Committee Members: Adam W. Anderson (committee member), Kevin C. Ess (committee member), Daniel F. Gochberg (committee member), John C. Gore (committee member), Mark D. Does (Committee Chair).
Subjects/Keywords: magnetization transfer; multiexponential T2; myelin; MRI; neuroimaging; histology; g-ratio
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
West, K. L. (2016). Development and Evaluation of Relaxation-Based Measures of Myelin Content and Microstructure in Rodent Brains. (Doctoral Dissertation). Vanderbilt University. Retrieved from http://hdl.handle.net/1803/14525
Chicago Manual of Style (16th Edition):
West, Kathryn Louise. “Development and Evaluation of Relaxation-Based Measures of Myelin Content and Microstructure in Rodent Brains.” 2016. Doctoral Dissertation, Vanderbilt University. Accessed January 16, 2021.
http://hdl.handle.net/1803/14525.
MLA Handbook (7th Edition):
West, Kathryn Louise. “Development and Evaluation of Relaxation-Based Measures of Myelin Content and Microstructure in Rodent Brains.” 2016. Web. 16 Jan 2021.
Vancouver:
West KL. Development and Evaluation of Relaxation-Based Measures of Myelin Content and Microstructure in Rodent Brains. [Internet] [Doctoral dissertation]. Vanderbilt University; 2016. [cited 2021 Jan 16].
Available from: http://hdl.handle.net/1803/14525.
Council of Science Editors:
West KL. Development and Evaluation of Relaxation-Based Measures of Myelin Content and Microstructure in Rodent Brains. [Doctoral Dissertation]. Vanderbilt University; 2016. Available from: http://hdl.handle.net/1803/14525

University of Texas – Austin
8.
Xiong, Bangguo.
Toward a geometric theory of magnetization dynamics : electronic contribution in the semiclassical approach.
Degree: PhD, Physics, 2019, University of Texas – Austin
URL: http://dx.doi.org/10.26153/tsw/2270
► This dissertation presents theoretical studies of the magnetization dynamics in ferromagnetic materials. To give a general description of the influences of electric fields or currents…
(more)
▼ This dissertation presents theoretical studies of the
magnetization dynamics in ferromagnetic materials. To give a general description of the influences of electric fields or currents on
magnetization dynamics, we developed a semiclassical theory for the
magnetization implicitly coupled to electronic degrees of freedom.
In the absence of electric fields, the Bloch electron Hamiltonian changes the Berry curvature, the effective H fields and the damping in the dynamical equation of the
magnetization, which we classify into intrinsic and extrinsic effects. Static electric field modifies these as first-order perturbations, with which we are able to give a physically clear interpretation of the current-induced spin-orbit torques.
In analogy of the electromagnetic fields, the Berry curvature is the magnetic field and the gradient of energy is the static electric field in the
magnetization space. If the system is driven by external forces, an additional Faraday H field appears. The Faraday H field can be provided by electron motion, e.g. in the presence of electric fields, giving the intrinsic spin-orbital torque. We use a toy model mimicking a ferromagnet-topological-insulator interface to illustrate the various effects, and we predict an anisotropic gyromagnetic ratio and the dynamical stability for an in-plane
magnetization.
In the presence of inhomogeneity, the Faraday H field can be provided by electron velocity, giving rise to the intrinsic spin-
transfer torque. In the semiclassical framework, the electronic spin dipole is found to influence the
magnetization dynamics in terms of Dzyaloshinskii-Mariya interaction. We obtain both the equilibrium spin dipole and the field-induced spin dipole, for the equilibrium and non-equilibrium Dzyaloshinskii-Mariya interaction, respectively. In addition, the induced effective H field has a geometric contribution in the second Chern form, extending the first Chern form in uniform systems. Our results provide methods for the electric field control of magnetic structures.
Advisors/Committee Members: Niu, Qian (advisor), MacDonald, Allan (committee member), Demkov, Alexander (committee member), Shih, Chih-Kang (committee member), Tutuc, Emanuel (committee member).
Subjects/Keywords: Magnetization dynamics; Spin-orbital torques; Spin-transfer torques; Semiclassical theory
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Xiong, B. (2019). Toward a geometric theory of magnetization dynamics : electronic contribution in the semiclassical approach. (Doctoral Dissertation). University of Texas – Austin. Retrieved from http://dx.doi.org/10.26153/tsw/2270
Chicago Manual of Style (16th Edition):
Xiong, Bangguo. “Toward a geometric theory of magnetization dynamics : electronic contribution in the semiclassical approach.” 2019. Doctoral Dissertation, University of Texas – Austin. Accessed January 16, 2021.
http://dx.doi.org/10.26153/tsw/2270.
MLA Handbook (7th Edition):
Xiong, Bangguo. “Toward a geometric theory of magnetization dynamics : electronic contribution in the semiclassical approach.” 2019. Web. 16 Jan 2021.
Vancouver:
Xiong B. Toward a geometric theory of magnetization dynamics : electronic contribution in the semiclassical approach. [Internet] [Doctoral dissertation]. University of Texas – Austin; 2019. [cited 2021 Jan 16].
Available from: http://dx.doi.org/10.26153/tsw/2270.
Council of Science Editors:
Xiong B. Toward a geometric theory of magnetization dynamics : electronic contribution in the semiclassical approach. [Doctoral Dissertation]. University of Texas – Austin; 2019. Available from: http://dx.doi.org/10.26153/tsw/2270

University of Toronto
9.
Skarsgard, Matthew.
Saturation Transfer Neuroimaging Features of Sickle Cell Anemia.
Degree: 2020, University of Toronto
URL: http://hdl.handle.net/1807/103525
► The broad symptomatology of sickle cell anemia (SCA) includes severe neurologic complications, such as stroke and cognitive impairment, from a young age in many patients.…
(more)
▼ The broad symptomatology of sickle cell anemia (SCA) includes severe neurologic complications, such as stroke and cognitive impairment, from a young age in many patients. Evidence suggests that chronic oxygen deprivation leads to alterations in cerebral blood flow, metabolism, and tissue microstructure which contribute to neurologic morbidity. We have proposed that saturation transfer MRI, an imaging modality sensitive to the microstructure and biochemical environment of tissues, could improve our understanding of neurologic pathology in SCA and have potential clinical utility for assessing disease severity. This thesis reports on a preclinical study to characterize saturation transfer neuroimaging features in a mouse model of SCA. The results of this study demonstrate that saturation transfer MRI is sensitive to microstructural and metabolic alterations in the normal-appearing grey matter of SCA mice. These findings warrant further investigation into saturation transfer neuroimaging as a research tool and a clinical biomarker of brain injury in SCA.
M.Sc.
Advisors/Committee Members: Sled, John G, Medical Biophysics.
Subjects/Keywords: CEST; Magnetization Transfer; MRI; Saturation Transfer; Sickle Cell Anemia; Sickle Cell Disease; 0574
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APA (6th Edition):
Skarsgard, M. (2020). Saturation Transfer Neuroimaging Features of Sickle Cell Anemia. (Masters Thesis). University of Toronto. Retrieved from http://hdl.handle.net/1807/103525
Chicago Manual of Style (16th Edition):
Skarsgard, Matthew. “Saturation Transfer Neuroimaging Features of Sickle Cell Anemia.” 2020. Masters Thesis, University of Toronto. Accessed January 16, 2021.
http://hdl.handle.net/1807/103525.
MLA Handbook (7th Edition):
Skarsgard, Matthew. “Saturation Transfer Neuroimaging Features of Sickle Cell Anemia.” 2020. Web. 16 Jan 2021.
Vancouver:
Skarsgard M. Saturation Transfer Neuroimaging Features of Sickle Cell Anemia. [Internet] [Masters thesis]. University of Toronto; 2020. [cited 2021 Jan 16].
Available from: http://hdl.handle.net/1807/103525.
Council of Science Editors:
Skarsgard M. Saturation Transfer Neuroimaging Features of Sickle Cell Anemia. [Masters Thesis]. University of Toronto; 2020. Available from: http://hdl.handle.net/1807/103525

Universidade do Rio Grande do Sul
10.
Accioly, Artur Difini.
Estudo do efeito de transferência de spin.
Degree: 2011, Universidade do Rio Grande do Sul
URL: http://hdl.handle.net/10183/29508
► A ideia de transferência de spin, como forma de controle da magnetização, foi introduzida independentemente por Slonczewski e por Berger em 1996. Desde então, esse…
(more)
▼ A ideia de transferência de spin, como forma de controle da magnetização, foi introduzida independentemente por Slonczewski e por Berger em 1996. Desde então, esse efeito tem sido alvo de inúmeras pesquisas, em especial pela possibilidade de aplicações em memorias magnéticas não voláteis e em osciladores de alta frequência. Devido _a complexidade do problema, a grande maioria das pesquisas teóricas sobre o assunto _e baseada em resultados numéricos. Porém, esses métodos podem dificultar a visualização das influências individuais dos diferentes termos envolvidos. Para isso, seria melhor a utilização de métodos analíticos, o que nos motiva a buscar por esses resultados. Nesse trabalho, apresentamos uma revisão sobre a teoria básica do efeito de transferência de spin e da dinâmica da magnetização. São revistas as principais equações que descrevem o comportamento da magnetização, as equações de Landau-Lifshitz e de Landau-Lifshitz-Gilbert, e comparadas suas componentes quando da inclusão do termo de transferência, analisando a melhor forma de incluir esse termo. É destacada a contribuição dada pelo termo de transferência na frequência de precessão da magnetização, que aparece ao se utilizar a equação de Landau-Lifshitz-Gilbert. Após essa revisão dos conceitos base, são buscadas soluções analíticas para a dinâmica da magnetização da camada livre de um sistema nanopilar em tricamada. Quatro casos são analisados: primeiro um sistema sem anisotropias e sem a inclusão do campo de Oersted, no segundo caso é incluído um termo de anisotropia e no terceiro novamente um sistema sem anisotropias, mas com a inclusão do campo de Oersted. Todas essas análises são feitas em uma aproximação de macrospin. Por último, uma aproximação de microspin com campo de Oersted. Nos três primeiros casos, é possível obter resultados analíticos e simular os resultados. São estimados o tempo de reversão e a frequência de precessão estável.
The idea of spin transfer as a way to control magnetization was introduced independently by Slonczewski and Berger in 1996. Since then, this e ect has been the subject of numerous studies, especially for potential applications in nonvolatile magnetic memories and high-frequency oscillators. Due to the complexity of the problem, the vast majority of theoretical research on this subject is based on numerical results. However, these methods might not display the in uences of individual terms involved. For this, it would be better to use analytical methods, which motivates us to search for these results. In this paper, we review the basic theory of spin transfer e ect and of magnetization dynamics. We review the main equations that describe the behavior of magnetization, the Landau-Lifshitz and Landau-Lifshitz-Gilbert equations, and compare its components when inserting the spin torque term, analyzing the best way to include this term. The contribution of spin transfer on magnetization precession frequency, which appears when using the Landau-Lifshitz- Gilbert equation, is emphasized. After this review of basic…
Advisors/Committee Members: Pereira, Luis Gustavo.
Subjects/Keywords: Spin; Spin transfer; Nanopillar; Magnetização; Magnetorresistência; Magnetization dynamics; Analytical solution; Stable precession
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
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APA (6th Edition):
Accioly, A. D. (2011). Estudo do efeito de transferência de spin. (Thesis). Universidade do Rio Grande do Sul. Retrieved from http://hdl.handle.net/10183/29508
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Accioly, Artur Difini. “Estudo do efeito de transferência de spin.” 2011. Thesis, Universidade do Rio Grande do Sul. Accessed January 16, 2021.
http://hdl.handle.net/10183/29508.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Accioly, Artur Difini. “Estudo do efeito de transferência de spin.” 2011. Web. 16 Jan 2021.
Vancouver:
Accioly AD. Estudo do efeito de transferência de spin. [Internet] [Thesis]. Universidade do Rio Grande do Sul; 2011. [cited 2021 Jan 16].
Available from: http://hdl.handle.net/10183/29508.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Accioly AD. Estudo do efeito de transferência de spin. [Thesis]. Universidade do Rio Grande do Sul; 2011. Available from: http://hdl.handle.net/10183/29508
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Vanderbilt University
11.
Harrigan, Robert Louis.
Optic Nerve Characterization using Magnetic Resonance Imaging: The Search for Biomarkers.
Degree: PhD, Electrical Engineering, 2017, Vanderbilt University
URL: http://hdl.handle.net/1803/10773
► The optic nerve is a vital bundle of axons which carries all visual information from the retina posterior to the brain for higher order processing.…
(more)
▼ The optic nerve is a vital bundle of axons which carries all visual information from the retina posterior to the brain for higher order processing. The optic nerve and eye orbit are affected by many devastating diseases including optic neuritis, glaucoma and anterior ischemic optic neuritis. This dissertation addresses the use of magnetic resonance imaging for investigating anatomical and microstructural changes in the optic nerve in healthy controls and disease cohorts.
We propose a fully automated pipeline for segmentation of the optic nerve and other eye-orbit structures. This pipeline is applied to large-scale disease cohort to search for correlations between morphological changes and functional visual measures. We introduce a clinically viable advanced MRI sequence for accurate visualization of the optic nerve and sub-arachnoid cerebrospinal fluid. We develop and improve upon an algorithm to automatically estimate optic nerve and surrounding cerebrospinal fluid radius along the length of the optic nerve. We perform a short- and long-term reproducibility study on young healthy controls for algorithm evaluation and publicly release this data for the standardized comparison of future proposed algorithms. We apply this validated automatic radius estimation algorithm to a clinical population of patients with multiple sclerosis to detect differences in patients’ eyes with and without a history of optic neuritis. Finally, we utilize a simulation framework to numerically optimize quantitative
magnetization transfer imaging sampling patterns to move towards reducing scan times and increasing clinical viability of quantitative
magnetization transfer imaging for microstructural characterization of tissue.
Advisors/Committee Members: David J. Calkins (committee member), Richard Alan Peters (committee member), Jack H. Noble (committee member), Seth A. Smith (Committee Chair), Bennett A. Landman (Committee Chair).
Subjects/Keywords: multi atlas segmentation; Optic nerve; conjugate gradient descent; magnetic resonance imaging; quantitative magnetization transfer
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APA (6th Edition):
Harrigan, R. L. (2017). Optic Nerve Characterization using Magnetic Resonance Imaging: The Search for Biomarkers. (Doctoral Dissertation). Vanderbilt University. Retrieved from http://hdl.handle.net/1803/10773
Chicago Manual of Style (16th Edition):
Harrigan, Robert Louis. “Optic Nerve Characterization using Magnetic Resonance Imaging: The Search for Biomarkers.” 2017. Doctoral Dissertation, Vanderbilt University. Accessed January 16, 2021.
http://hdl.handle.net/1803/10773.
MLA Handbook (7th Edition):
Harrigan, Robert Louis. “Optic Nerve Characterization using Magnetic Resonance Imaging: The Search for Biomarkers.” 2017. Web. 16 Jan 2021.
Vancouver:
Harrigan RL. Optic Nerve Characterization using Magnetic Resonance Imaging: The Search for Biomarkers. [Internet] [Doctoral dissertation]. Vanderbilt University; 2017. [cited 2021 Jan 16].
Available from: http://hdl.handle.net/1803/10773.
Council of Science Editors:
Harrigan RL. Optic Nerve Characterization using Magnetic Resonance Imaging: The Search for Biomarkers. [Doctoral Dissertation]. Vanderbilt University; 2017. Available from: http://hdl.handle.net/1803/10773

Texas A&M University
12.
Vehstedt, Erin Kathleen.
Spin-Orbit Torque Driven Magnetization Dynamics in (Ga,Mn)As and (Ga,Mn)(As,P) Dilute Magnetic Semiconductors.
Degree: MS, Physics, 2014, Texas A&M University
URL: http://hdl.handle.net/1969.1/153402
► Spintronics-based technologies are poised to leapfrog the current limitations on the scaling, speed, and power consumption of electronic devices. Conventional devices rely on complex structures…
(more)
▼ Spintronics-based technologies are poised to leapfrog the current limitations on the scaling, speed, and power consumption of electronic devices. Conventional devices rely on complex structures and magnetic-field-based switching to manipulate data. In order to overcome these limits, new methods must be developed to reliably transmit and store data more efficiently. The understanding and manipulation of magnetic domain walls (DWs) may play a pivotal role in the development of new
non-volatile and down-scalable logic and memory devices.
This thesis investigates current-induced
magnetization dynamics and control mechanisms in the ideal ferromagnetic semiconductors Phosphorus-doped Gallium Manganese Arsenide (Ga,Mn)(As,P) and Gallium Manganese Arsenide (Ga,Mn)As. In spin-orbit (SO) coupled materials with broken inversion symmetry, unpolarized electric fields provide a means to control
magnetization orientation via the inverse spin-galvanic effect (ISGE). The ISGE generates a non-equilibrium spin-accumulation
which can exert a torque on a
magnetization if the spins are generated in (or injected into) a ferromagnetic material. This so-called current-induced spin-orbit torque (SOT) is calculated for a broad range of experimental parameters and compared with previous measurements.
The study also assess the viability of using SOTs to control DW motion in semiconductor micro-structures. Typically, DW mobility is divided into steady and precession motion regimes with different mobilities, separated by the so-called Walker breakdown (WB). By manipulating the magnetic anisotropy of (Ga,Mn)(As,P) using piezoelectric strain, these experiments investigate the potential of strain to shift the WB, establishing strain-modified DW mobility as tool for electrically controlled DW motion.
Advisors/Committee Members: Sinova, Jairo (advisor), Ross, Joseph H (committee member), Harris, Harlan R (committee member).
Subjects/Keywords: Spintronics; Spin-Transfer-Torque; Magnetization Dynamics; Semiconductors; Spin Orbit Couping; GaMnAs; GaMnAsP; Domain Wall Motion
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Vehstedt, E. K. (2014). Spin-Orbit Torque Driven Magnetization Dynamics in (Ga,Mn)As and (Ga,Mn)(As,P) Dilute Magnetic Semiconductors. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/153402
Chicago Manual of Style (16th Edition):
Vehstedt, Erin Kathleen. “Spin-Orbit Torque Driven Magnetization Dynamics in (Ga,Mn)As and (Ga,Mn)(As,P) Dilute Magnetic Semiconductors.” 2014. Masters Thesis, Texas A&M University. Accessed January 16, 2021.
http://hdl.handle.net/1969.1/153402.
MLA Handbook (7th Edition):
Vehstedt, Erin Kathleen. “Spin-Orbit Torque Driven Magnetization Dynamics in (Ga,Mn)As and (Ga,Mn)(As,P) Dilute Magnetic Semiconductors.” 2014. Web. 16 Jan 2021.
Vancouver:
Vehstedt EK. Spin-Orbit Torque Driven Magnetization Dynamics in (Ga,Mn)As and (Ga,Mn)(As,P) Dilute Magnetic Semiconductors. [Internet] [Masters thesis]. Texas A&M University; 2014. [cited 2021 Jan 16].
Available from: http://hdl.handle.net/1969.1/153402.
Council of Science Editors:
Vehstedt EK. Spin-Orbit Torque Driven Magnetization Dynamics in (Ga,Mn)As and (Ga,Mn)(As,P) Dilute Magnetic Semiconductors. [Masters Thesis]. Texas A&M University; 2014. Available from: http://hdl.handle.net/1969.1/153402
13.
Bouazizi Verdier, Khaoula.
Caractérisation de l’os cortical par IRM à temps d’écho ultra-court (UTE) : Cortical bone characterization using UTE-MRI.
Degree: Docteur es, Imagerie et physique médicale, 2015, Université Paris-Saclay (ComUE)
URL: http://www.theses.fr/2015SACLS164
► On utilise en IRM clinique T2, T1 et la densité de protons comme biomarqueurs de diagnostic et de suivi. Cependant, seuls les tissus à T2…
(more)
▼ On utilise en IRM clinique T2, T1 et la densité de protons comme biomarqueurs de diagnostic et de suivi. Cependant, seuls les tissus à T2 long sont visibles par IRM classique. La séquence UTE (Ultra-short TE) a été récemment développée pour des études quantitatives de l’os cortical. Nous avons dans une première étape confronté des mesures de porosité de l’os cortical par IRM-UTE et par microtomographie par rayonnement synchrotron, car la porosité est un paramètre déterminant de la qualité osseuse. L’étude a été menée sur 38 échantillons de diaphyses fémorales humaines en collaboration avec une équipe du B2OA (UMR7052). La porosité par IRM-UTE à 4.7 T (TE = 51 µs) est entre 18 et 43% (moyenne 30%). La porosité par microtomographie (résolution spatiale : 6.5 µm) est entre 3 et 27% (moyenne 14%). Aucune corrélation n’a pu être observée entre les deux mesures. Une importante dispersion a été observée sur les valeurs de T1 entre les échantillons, que nous proposons d’attribuer à des effets de transfert d’aimantation (MT) entre les protons de l’eau liée au collagène et les protons des terminaisons méthylène du collagène. Pour confirmer cette interprétation, nous avons dans une seconde étape confronté plusieurs méthodes d’évaluation de la relaxation longitudinale dans des échantillons d’os bovin. Les mesures réalisées par différentes séquences (inversion-récupération, saturation hors-résonance, saturation par répétition de binomiales et angle de bascule variable) confirment des effets de MT importants. Les méthodes les plus robustes pour évaluer les paramètres sont la saturation hors-résonance et par répétition de binomiales, ce qui suggère leur utilisation pour de futures applications in vivo.
Longitudinal and transverse relaxations are quantitative tools used in MRI for diagnosis and follow up. However only tissues with long T2 can be detected with MRI. Quantitative evaluation of cortical bone porosity is now feasible with UTE.In this work, porosity measurements from UTE in human cortical bone samples were compared with those from micro-computed tomography (µCT). 38 human cortical bone samples (upper diaphysis) were examined in collaboration with a team from B2OA (UMR7052). Porosity from UTE (TE = 51 µs) was between 18% and 43% (mean 30%) and from µCT (spatial resolution = 6.5 µm) between 3% and 27% (mean 14%). No correlation could be established between the two measurements. T1 values from few samples were dispersed; a possible explanation could be the magnetization transfer (MT) between collagen-bound water protons and collagen methylene protons.For a quantitative interpretation of this phenomenon, 11 bovine cortical bone samples were examined. Several sequences (inversion-recovery, off-resonance saturation, repeated binomial excitations, variable flip angle) were implemented at 4.7 T to assess MT parameters. The aim was to compare which method may provide accurate parameter estimation. Off-resonance saturation and repeated binomial excitation seem to be more suitable for in vivo MT quantification.
Advisors/Committee Members: Guillot, Geneviève (thesis director).
Subjects/Keywords: Irm; Ute; Os cortical; Porosité; Transfert d'aimantation; Mri; Ute; Cortical bone; Porosity; Magnetization transfer
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APA ·
Chicago ·
MLA ·
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Export
to Zotero / EndNote / Reference
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APA (6th Edition):
Bouazizi Verdier, K. (2015). Caractérisation de l’os cortical par IRM à temps d’écho ultra-court (UTE) : Cortical bone characterization using UTE-MRI. (Doctoral Dissertation). Université Paris-Saclay (ComUE). Retrieved from http://www.theses.fr/2015SACLS164
Chicago Manual of Style (16th Edition):
Bouazizi Verdier, Khaoula. “Caractérisation de l’os cortical par IRM à temps d’écho ultra-court (UTE) : Cortical bone characterization using UTE-MRI.” 2015. Doctoral Dissertation, Université Paris-Saclay (ComUE). Accessed January 16, 2021.
http://www.theses.fr/2015SACLS164.
MLA Handbook (7th Edition):
Bouazizi Verdier, Khaoula. “Caractérisation de l’os cortical par IRM à temps d’écho ultra-court (UTE) : Cortical bone characterization using UTE-MRI.” 2015. Web. 16 Jan 2021.
Vancouver:
Bouazizi Verdier K. Caractérisation de l’os cortical par IRM à temps d’écho ultra-court (UTE) : Cortical bone characterization using UTE-MRI. [Internet] [Doctoral dissertation]. Université Paris-Saclay (ComUE); 2015. [cited 2021 Jan 16].
Available from: http://www.theses.fr/2015SACLS164.
Council of Science Editors:
Bouazizi Verdier K. Caractérisation de l’os cortical par IRM à temps d’écho ultra-court (UTE) : Cortical bone characterization using UTE-MRI. [Doctoral Dissertation]. Université Paris-Saclay (ComUE); 2015. Available from: http://www.theses.fr/2015SACLS164

Georgia Tech
14.
Kani, Nickvash.
Modeling of magnetization dynamics and applications to spin-based logic and memory devices.
Degree: PhD, Electrical and Computer Engineering, 2017, Georgia Tech
URL: http://hdl.handle.net/1853/59242
► The objective of this research is to develop models to better evaluate the performance and reliability of proposed spin-based boolean devices. This research will focus…
(more)
▼ The objective of this research is to develop models to better evaluate the performance and reliability of proposed spin-based boolean devices. This research will focus on a particular spin-based logic technology called Spin-Switch Logic. There are two primary reversal mechanisms that will be considered for a full evaluation of Spin-Switch technology. Firstly, nanomagnet reversal through the use of spin-
transfer torque (STT) is studied. While switching through STT has been analytically solved for the uniaxial nanomagnet case, the biaxial case has yet to be studied on a sufficient scale and will be a focus of this research.
Secondly, input-output isolation is achieved through dipolar coupling; hence, the performance and reliability of this type of reversal mechanism is extensively studied. It is shown that dipolar coupling strength is not only a function of geometric and material parameters, but also of reversal speed. If the reversal of a neighboring nanomagnet is very fast, the dipolar field reduces to a constant longitudinal field and can be analytically studied. However, if the reversal of the neighboring nanomagnet is slow, new models are needed to estimate the region of reliable coupling and delay.
Lastly, a focal point of this research will be on the reliability of nanomagnet states in the presence of thermal noise and new models are proposed to estimate the reliability of complex spin-based systems. Not only does the thermal noise affect the probability of
magnetization state consistency, it also alters nanomagnet precession during reversal, making the delay a random variable. Hence, models are developed for evaluating the variation in reversal delay through STT for both uniaxial and biaxial cases.
Ultimately, these analytic models are combined to comprehensively evaluate the performance of Spin-Switch technology and identify possible improvements to this technology. While the end result of this research will be a thorough analysis of Spin-Switch logic, the models developed during this research are applicable to a variety of spin-based logic and memory technologies.
Advisors/Committee Members: Gaylord, Thomas K. (advisor), Naeemi, Azad J. (committee member), Davis, Jeffrey A. (committee member), Yalamanchili, Sudhakar (committee member), Jacobs, Laurence J. (committee member).
Subjects/Keywords: Nanomagnet; Dipolar coupling; Spin-transfer torque; Magnetic tunnel junction; Spin-switch; Spintronics; Straintronics; Magnetization dynamics
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Kani, N. (2017). Modeling of magnetization dynamics and applications to spin-based logic and memory devices. (Doctoral Dissertation). Georgia Tech. Retrieved from http://hdl.handle.net/1853/59242
Chicago Manual of Style (16th Edition):
Kani, Nickvash. “Modeling of magnetization dynamics and applications to spin-based logic and memory devices.” 2017. Doctoral Dissertation, Georgia Tech. Accessed January 16, 2021.
http://hdl.handle.net/1853/59242.
MLA Handbook (7th Edition):
Kani, Nickvash. “Modeling of magnetization dynamics and applications to spin-based logic and memory devices.” 2017. Web. 16 Jan 2021.
Vancouver:
Kani N. Modeling of magnetization dynamics and applications to spin-based logic and memory devices. [Internet] [Doctoral dissertation]. Georgia Tech; 2017. [cited 2021 Jan 16].
Available from: http://hdl.handle.net/1853/59242.
Council of Science Editors:
Kani N. Modeling of magnetization dynamics and applications to spin-based logic and memory devices. [Doctoral Dissertation]. Georgia Tech; 2017. Available from: http://hdl.handle.net/1853/59242

Delft University of Technology
15.
Kovalev, A.A.
Electrical and mechanical magnetization torques.
Degree: 2006, Delft University of Technology
URL: http://resolver.tudelft.nl/uuid:ba55eaf7-80ff-4225-b2e1-d5f3cebcabdb
;
urn:NBN:nl:ui:24-uuid:ba55eaf7-80ff-4225-b2e1-d5f3cebcabdb
;
urn:NBN:nl:ui:24-uuid:ba55eaf7-80ff-4225-b2e1-d5f3cebcabdb
;
http://resolver.tudelft.nl/uuid:ba55eaf7-80ff-4225-b2e1-d5f3cebcabdb
► Only charge degree of freedom is utilized in most electronic devices. The use of the spin degree of freedom is relatively recent. The discovery of…
(more)
▼ Only charge degree of freedom is utilized in most electronic devices. The use of the spin degree of freedom is relatively recent. The discovery of the Giant Magnetoresistance (GMR) effect initiated the development of magnetoelectronics - the field that studies effects on electron transport involving the spin degree of freedom. GMR is a very large change in electrical resistance observed in ferromagnet/nonmagnet multilayer structures when the relative orientations of the magnetizations in ferromagnetic layers change as a function of applied field. The development of magnetoelectronics was very rapid leading to useful applications already within several years. For example, the GMR effect is presently routinely used to sense magnetic fields of data in read heads of magnetic hard disk drives. Whereas in GMR the relative direction of the magnetizations defines the current flowing through the system, an opposite effect of current on the magnetizations is also possible. Slonczewski predicted this effect - the spin
transfer torque. In a ferromagnet/normal metal/ferromagnet structure with one
magnetization free and the other fixed, the
magnetization dynamics of the free layer can be driven by a current through the system as a result of spin-
transfer torques. The
magnetization dynamics in small magnetic clusters and films is a basic problem of condensed matter physics and is also important for applications: the spin-
transfer effect may find applications in the so-called magnetic random access memories in which the direction of the
magnetization is used to store the data and the rewriting process can be done by spin-
transfer torques. Magnetoelectronics is a rapidly developing field at the moment and this thesis deals with some aspects of it related to
magnetization dynamics and torques. The main
subject of the thesis is torque, i.e. a change of angular momentum in time. We deal with torques that arise in spin valves and small magnetic cantilevers; spin-
transfer torques in the former and magnetomechanical torques in the latter case. In order to describe spin-
transfer torques we develop an approach based on the diffusion equation with quantum mechanical boundary conditions. With some simplifications this leads to magnetoelectronic circuit theory. This allows us to treat arbitrary diffuse spin valves and other devices. Magnetomechanical torques arise in small magnetic cantilevers. An example is a cantilever with one end fixed and the other covered with a magnetic film. It is important that the magnetic film has strong crystal or shape magnetic anisotropy, which provides coupling between vibrations and the
magnetization dynamics. The anisotropy in the film leads to magnetomechanical torques that affect both the
magnetization dynamics and the mechanical motion of the cantilever. This can open new possibilities for Magnetic Resonance Force Microscopy in imaging and sensor applications. In Chapter 1 of this thesis we introduce the basic concepts of magnetoelectronics such as the spin-polarized current, the GMR effect, the…
Advisors/Committee Members: Bauer, G.E.W., Brataas, A..
Subjects/Keywords: magnetoelectronics; nanomechanics; spin transfer; magnetization dynamics
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Kovalev, A. A. (2006). Electrical and mechanical magnetization torques. (Doctoral Dissertation). Delft University of Technology. Retrieved from http://resolver.tudelft.nl/uuid:ba55eaf7-80ff-4225-b2e1-d5f3cebcabdb ; urn:NBN:nl:ui:24-uuid:ba55eaf7-80ff-4225-b2e1-d5f3cebcabdb ; urn:NBN:nl:ui:24-uuid:ba55eaf7-80ff-4225-b2e1-d5f3cebcabdb ; http://resolver.tudelft.nl/uuid:ba55eaf7-80ff-4225-b2e1-d5f3cebcabdb
Chicago Manual of Style (16th Edition):
Kovalev, A A. “Electrical and mechanical magnetization torques.” 2006. Doctoral Dissertation, Delft University of Technology. Accessed January 16, 2021.
http://resolver.tudelft.nl/uuid:ba55eaf7-80ff-4225-b2e1-d5f3cebcabdb ; urn:NBN:nl:ui:24-uuid:ba55eaf7-80ff-4225-b2e1-d5f3cebcabdb ; urn:NBN:nl:ui:24-uuid:ba55eaf7-80ff-4225-b2e1-d5f3cebcabdb ; http://resolver.tudelft.nl/uuid:ba55eaf7-80ff-4225-b2e1-d5f3cebcabdb.
MLA Handbook (7th Edition):
Kovalev, A A. “Electrical and mechanical magnetization torques.” 2006. Web. 16 Jan 2021.
Vancouver:
Kovalev AA. Electrical and mechanical magnetization torques. [Internet] [Doctoral dissertation]. Delft University of Technology; 2006. [cited 2021 Jan 16].
Available from: http://resolver.tudelft.nl/uuid:ba55eaf7-80ff-4225-b2e1-d5f3cebcabdb ; urn:NBN:nl:ui:24-uuid:ba55eaf7-80ff-4225-b2e1-d5f3cebcabdb ; urn:NBN:nl:ui:24-uuid:ba55eaf7-80ff-4225-b2e1-d5f3cebcabdb ; http://resolver.tudelft.nl/uuid:ba55eaf7-80ff-4225-b2e1-d5f3cebcabdb.
Council of Science Editors:
Kovalev AA. Electrical and mechanical magnetization torques. [Doctoral Dissertation]. Delft University of Technology; 2006. Available from: http://resolver.tudelft.nl/uuid:ba55eaf7-80ff-4225-b2e1-d5f3cebcabdb ; urn:NBN:nl:ui:24-uuid:ba55eaf7-80ff-4225-b2e1-d5f3cebcabdb ; urn:NBN:nl:ui:24-uuid:ba55eaf7-80ff-4225-b2e1-d5f3cebcabdb ; http://resolver.tudelft.nl/uuid:ba55eaf7-80ff-4225-b2e1-d5f3cebcabdb

University of Maryland
16.
Lee, Andrew Wuham.
Stochastic Magnetization Dynamics Driven by a Jump-Noise Process.
Degree: Electrical Engineering, 2015, University of Maryland
URL: http://hdl.handle.net/1903/16906
► An approach to modeling thermal noise effects in stochastic magnetization dynamics using a jump-noise process is presented. The damping term present in classical Landau-Lifshitz and…
(more)
▼ An approach to modeling thermal noise effects in stochastic
magnetization dynamics using a jump-noise process is presented. The damping term present in classical Landau-Lifshitz and Landau-Lifshitz-Gilbert equations is shown to result from the average of the jump-noise process in the presented stochastic Landau-Lifshitz equation approach. A numerical technique for solving the Landau-Lifshitz equation driven by a jump-noise process based on the Monte Carlo method is introduced and the results obtained from this method are shown. The drawback of using the Monte Carlo approach is discussed as well as the introduction of an averaging method to model stochastic
magnetization dynamics on energy graphs. This averaging technique takes advantage of the difference in time-scale between the precessional motion and thermal effects in the stochastic Landau-Lifshitz model. By averaging over precessional trajectories, a stochastic
magnetization dynamics equation on graphs is obtained. This averaging technique is demonstrated to be consistent with Monte Carlo results through numerical simulations. Application of the averaging technique to self-oscillations in
magnetization dynamics due to the spin-
transfer torque phenomenon is investigated and numerical results are presented. Finally, the power spectral density for
magnetization dynamics on energy graphs is calculated. Numerical results for the power spectral density are studied and analyzed.
Advisors/Committee Members: Mayergoyz, Isaak (advisor).
Subjects/Keywords: Electrical engineering; Theoretical physics; Physics; Averaging Technique; Jump-Noise Process; Magnetization Dynamics; Spin-Transfer Torque
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Lee, A. W. (2015). Stochastic Magnetization Dynamics Driven by a Jump-Noise Process. (Thesis). University of Maryland. Retrieved from http://hdl.handle.net/1903/16906
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Lee, Andrew Wuham. “Stochastic Magnetization Dynamics Driven by a Jump-Noise Process.” 2015. Thesis, University of Maryland. Accessed January 16, 2021.
http://hdl.handle.net/1903/16906.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Lee, Andrew Wuham. “Stochastic Magnetization Dynamics Driven by a Jump-Noise Process.” 2015. Web. 16 Jan 2021.
Vancouver:
Lee AW. Stochastic Magnetization Dynamics Driven by a Jump-Noise Process. [Internet] [Thesis]. University of Maryland; 2015. [cited 2021 Jan 16].
Available from: http://hdl.handle.net/1903/16906.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Lee AW. Stochastic Magnetization Dynamics Driven by a Jump-Noise Process. [Thesis]. University of Maryland; 2015. Available from: http://hdl.handle.net/1903/16906
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

The Ohio State University
17.
Clark, Daniel James.
Chemical Exchange Saturation Transfer and Quantitative MRI
Methods: Applications for Osteoarthritis and Cartilage
Injury.
Degree: PhD, Biomedical Engineering, 2015, The Ohio State University
URL: http://rave.ohiolink.edu/etdc/view?acc_num=osu1431016691
► Osteoarthritis (OA) is a huge disease burden in United States, affecting almost 30 million Americans, and is the leading cause of disability in the elderly.…
(more)
▼ Osteoarthritis (OA) is a huge disease burden in United
States, affecting almost 30 million Americans, and is the leading
cause of disability in the elderly. Knee and hip replacements cost
over $40 billion annually, but may be avoided through early
detection of at risk cartilage and early intervention. There are
abundant MRI tools for non-invasive, quantitative imaging that
reveal characteristics of cartilage structure and physiology such
as collagen alignment, molecular content, and health of subchondral
bone vasculature. However, no quantitative MRI technique has been
added to clinical standard of care for cartilage imaging because of
lack of specificity and technical difficulty. Chemical exchange
saturation
transfer (CEST) MRI is a promising technique to detect
small metabolites such as glutamate, creatine and glucose, as well
as large soluble molecules such as protein, proteoglycans, and
glycogen. It has been demonstrated that CEST MRI can detect
glycosaminoglycan (GAG), a proteoglycan crucial to the functioning
of healthy articular cartilage, however only with high-field
non-clinical scanners (> 3 Tesla). In osteoarthritis
development, reduction in GAG content is a preliminary step before
gross changes in cartilage thickness and joint space, and therefore
clinical methods to detect GAG may have a tremendous impact on OA
prevention. In this dissertation, we discuss multiple quantitative
MRI techniques used to characterize articular cartilage, but then
focus on CEST MRI. A miniature horse model of cartilage injury is
used to evaluate several MRI techniques through serial imaging of
the healing process over the course of one year. While promising,
the techniques lack specificity and are technically challenging to
perform, especially delayed gadolinium enchance MRI of cartilage
(dGEMRIC), a technique used to detect GAG content. To meet the
challenge of GAG detection at 3 Tesla, we hypothesized that a
variant of CEST, using a novel variable saturation power (vCEST)
scheme could detect the hydroxyl protons of the GAG molecule. We
show through phantom studies that vCEST robustly detects glycogen
and glucose (hydroxyl rich molecules) in multiple environments
(aqueous, multiple solutes, and within semi-solid tissue), an
improvement over typical CEST MRI. We offer in vivo imaging that
shows contrast between lesions and normal cartilage using vCEST
that is not apparent in typical CEST imaging. Finally, we propose
an extension of vCEST that combines it with quantitative
magnetization transfer (qMT). We use in vivo imaging of a healthy
brain to show that vCEST/qMT can produce hydroxyl, amine/amide, and
NOE maps that are consistent with results achieved at higher
field-strengths. Since GAG molecules, in addition to hydroxyl
moieties, also have an amine proton in each disaccharide unit, we
hypothesize that the vCEST/qMT combine technique might further
specify GAG detection at 3 T, which will be included in future
work.The theme of this work is cartilage imaging, but it focuses on
developing a novel technology for molecular…
Advisors/Committee Members: Knopp, Michael (Advisor).
Subjects/Keywords: Biomedical Engineering; Medical Imaging; chemical exchange; CEST; magnetization transfer; MRI; cartilage; glycosaminoglycan
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Clark, D. J. (2015). Chemical Exchange Saturation Transfer and Quantitative MRI
Methods: Applications for Osteoarthritis and Cartilage
Injury. (Doctoral Dissertation). The Ohio State University. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=osu1431016691
Chicago Manual of Style (16th Edition):
Clark, Daniel James. “Chemical Exchange Saturation Transfer and Quantitative MRI
Methods: Applications for Osteoarthritis and Cartilage
Injury.” 2015. Doctoral Dissertation, The Ohio State University. Accessed January 16, 2021.
http://rave.ohiolink.edu/etdc/view?acc_num=osu1431016691.
MLA Handbook (7th Edition):
Clark, Daniel James. “Chemical Exchange Saturation Transfer and Quantitative MRI
Methods: Applications for Osteoarthritis and Cartilage
Injury.” 2015. Web. 16 Jan 2021.
Vancouver:
Clark DJ. Chemical Exchange Saturation Transfer and Quantitative MRI
Methods: Applications for Osteoarthritis and Cartilage
Injury. [Internet] [Doctoral dissertation]. The Ohio State University; 2015. [cited 2021 Jan 16].
Available from: http://rave.ohiolink.edu/etdc/view?acc_num=osu1431016691.
Council of Science Editors:
Clark DJ. Chemical Exchange Saturation Transfer and Quantitative MRI
Methods: Applications for Osteoarthritis and Cartilage
Injury. [Doctoral Dissertation]. The Ohio State University; 2015. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=osu1431016691

Université Paris-Sud – Paris XI
18.
Gorchon, Jon.
Current and field induced magnetization reversal in Pt/Co/Pt and (Ga, Mn)(As, P) ferromagnetic films : Retournement de l’aimantation par courant et champ magnétique dans les films ferromagnétiques de Pt/Co/Pt et (Ga,Mn)(As,P).
Degree: Docteur es, Physique, 2014, Université Paris-Sud – Paris XI
URL: http://www.theses.fr/2014PA112143
► La manipulation de l’état magnétique d’un système ferromagnétique présente un grand intérêt en raison de possibles applications technologiques. Comprendre les mécanismes fondamentaux qui contrôlent l’aimantation…
(more)
▼ La manipulation de l’état magnétique d’un système ferromagnétique présente un grand intérêt en raison de possibles applications technologiques. Comprendre les mécanismes fondamentaux qui contrôlent l’aimantation est donc particulièrement important. La compréhension de certains mécanismes peut également avoir un impact dans d’autres domaines de la physique. C’est le cas par exemple de la dynamique de déplacement de parois de domaines sous champ magnétique dans le régime de reptation (creep) qui peut être assimilé à celui d’une interface élastique et qui présente un caractère universel. Cette thèse présente tout d’abord, à travers un travail expérimental sur des couches ultra-minces de Pt/Co/Pt, une description complète de la dynamique de déplacement de parois de domaines sous champ magnétique. Une analyse auto-cohérente permet d’extraire tous les paramètres de contrôle, des exposants universels sont confirmés et un nouveau régime dynamique (le TAFF) est identifié. Une deuxième étude porte sur le déplacement de parois sous courant électrique en géométrie étendue dans un film de (Ga,Mn)(As,P). Cette étude met en évidence des instabilités de forme des parois de domaines soumises à un gradient de courant électrique. Les limites de stabilités sont analytiquement prédites et présentent un bon accord avec les expériences. Un troisième travail porte sur le renversement de l’aimantation à l’interface entre un film de (Ga,Mn)(As,P) et une électrode non ferromagnétique. Un renversement stochastique de l’aimantation sous courant continu est mis en évidence. Son origine réside dans l’accumulation de spin à l’interface qui diminue fortement l’aimantation locale. Un modèle simplifié permet de décrire la probabilité de retournement de l’aimantation et d’extraire les temps caractéristiques associés.
Effectively manipulating the magnetic state of a ferromagnet has a great interest for possible technological applications. Understanding the underlying fundamental mechanisms is thus particularly important. In some cases, the understanding of some mechanisms may even importantly impact other areas of physics. This is the case for example with field induced magnetic domain walls motion in the creep regime, where the wall can be assimilated to an elastic interface and follows an universal behavior. This thesis presents through an experimental work on Pt/Co/Pt ultra-thin samples, a complete description of the temperature and field dependent domain wall dynamics. A self-consistent analysis allows the extraction of all control parameters, identifying the new Thermally Activated Flux Flow regime, and confirming universal thermal scaling exponents. A second study focuses on current induced domain wall motion in an extended geometry of a (Ga,Mn)(As,P) ferromagnetic film. This study unveils domain wall shape instabilities under a gradient of current. The instability limits are analytically predicted in agreement with the experimental observations. A third work concerns the magnetization reversal mechanism evidenced at the interface between a…
Advisors/Committee Members: Jeudy, Vincent (thesis director).
Subjects/Keywords: Aimantation; Dynamique; Spin; Transfer; Creep; Instabilités; Universalité; Stochastique; Renversement; Magnetization; Dynamics; Spin; Transfer; Creep; Instabilities; Universality; Stochastic; Reversal
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Gorchon, J. (2014). Current and field induced magnetization reversal in Pt/Co/Pt and (Ga, Mn)(As, P) ferromagnetic films : Retournement de l’aimantation par courant et champ magnétique dans les films ferromagnétiques de Pt/Co/Pt et (Ga,Mn)(As,P). (Doctoral Dissertation). Université Paris-Sud – Paris XI. Retrieved from http://www.theses.fr/2014PA112143
Chicago Manual of Style (16th Edition):
Gorchon, Jon. “Current and field induced magnetization reversal in Pt/Co/Pt and (Ga, Mn)(As, P) ferromagnetic films : Retournement de l’aimantation par courant et champ magnétique dans les films ferromagnétiques de Pt/Co/Pt et (Ga,Mn)(As,P).” 2014. Doctoral Dissertation, Université Paris-Sud – Paris XI. Accessed January 16, 2021.
http://www.theses.fr/2014PA112143.
MLA Handbook (7th Edition):
Gorchon, Jon. “Current and field induced magnetization reversal in Pt/Co/Pt and (Ga, Mn)(As, P) ferromagnetic films : Retournement de l’aimantation par courant et champ magnétique dans les films ferromagnétiques de Pt/Co/Pt et (Ga,Mn)(As,P).” 2014. Web. 16 Jan 2021.
Vancouver:
Gorchon J. Current and field induced magnetization reversal in Pt/Co/Pt and (Ga, Mn)(As, P) ferromagnetic films : Retournement de l’aimantation par courant et champ magnétique dans les films ferromagnétiques de Pt/Co/Pt et (Ga,Mn)(As,P). [Internet] [Doctoral dissertation]. Université Paris-Sud – Paris XI; 2014. [cited 2021 Jan 16].
Available from: http://www.theses.fr/2014PA112143.
Council of Science Editors:
Gorchon J. Current and field induced magnetization reversal in Pt/Co/Pt and (Ga, Mn)(As, P) ferromagnetic films : Retournement de l’aimantation par courant et champ magnétique dans les films ferromagnétiques de Pt/Co/Pt et (Ga,Mn)(As,P). [Doctoral Dissertation]. Université Paris-Sud – Paris XI; 2014. Available from: http://www.theses.fr/2014PA112143

University of Western Ontario
19.
Booth, William J.
Reductions in Muscle Quantity and Quality in Old and Very Old Men: New Insights into the Progression of Sarcopenia.
Degree: 2012, University of Western Ontario
URL: https://ir.lib.uwo.ca/etd/511
► Healthy adult aging is associated with sarcopenia; a loss of skeletal muscle mass known as. Major contributors to this process include functional and morphological changes…
(more)
▼ Healthy adult aging is associated with sarcopenia; a loss of skeletal muscle mass known as. Major contributors to this process include functional and morphological changes in the contractile tissue and within the neuromuscular system. Currently, the relationship between muscle mass, normalized strength, structural integrity, and neuromuscular properties [such as motor unit number estimates (MUNE)], in the tibialis anterior (TA) with aging is largely unknown. Therefore, to examine this relationship we recruited twelve young (25 ± 3 years old), six old (68 ± 5 years old) and six very old (79 ± 3 years old) men. Magnetic resonance (MR) images were obtained from the entire musculature of the leg from the tibial plateau to the malleoli. Muscle cross-sectional areas (CSA) were calculated using image processing software. Strength was measured as maximal isometric voluntary dorsiflexion contraction (MVC) torque; this was then normalized to CSA. Structural integrity of the muscle was evaluated by magnetization transfer ratio (MTR) using magnetic resonance imaging (MRI). Neuromuscular measures were also collected and decomposition-enhanced spike-triggered averaging was used to collect surface and intramuscular electromyography (EMG) signals. From these data, estimates of motor unit numbers were made. Muscle CSA was less only in the very old (11.2cm2), no differences existed between the young (13.4cm2) and old (11.7cm2). Strength was ~26% lower in the old and ~24% in the very old than the young. When strength was normalized to CSA there were no differences between the groups. Very old men had ~8% lower MTR values than the young and old men, with no differences between young and old. Neuromuscular measures, specifically the combination of a decreased compound muscle action potential (CMAP) and increased surface motor unit potential (SMUP), resulted in a decrease in MUNE between young [~147 motor units (MU)] and old (~109 MUs) and also between young and very old (~80 MUs). In conclusion, muscular structure and function appear to be maintained in the older adult due to compensatory motor unit remodeling; however in the very old adult the structural integrity of the muscle becomes compromised as motor unit losses are greater resulting in the acceleration of sarcopenia.
Subjects/Keywords: aging; normalized strength; magnetic resonance imaging; magnetization transfer ratio; motor unit number estimates; neuromuscular; Other Medicine and Health Sciences
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Booth, W. J. (2012). Reductions in Muscle Quantity and Quality in Old and Very Old Men: New Insights into the Progression of Sarcopenia. (Thesis). University of Western Ontario. Retrieved from https://ir.lib.uwo.ca/etd/511
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Booth, William J. “Reductions in Muscle Quantity and Quality in Old and Very Old Men: New Insights into the Progression of Sarcopenia.” 2012. Thesis, University of Western Ontario. Accessed January 16, 2021.
https://ir.lib.uwo.ca/etd/511.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Booth, William J. “Reductions in Muscle Quantity and Quality in Old and Very Old Men: New Insights into the Progression of Sarcopenia.” 2012. Web. 16 Jan 2021.
Vancouver:
Booth WJ. Reductions in Muscle Quantity and Quality in Old and Very Old Men: New Insights into the Progression of Sarcopenia. [Internet] [Thesis]. University of Western Ontario; 2012. [cited 2021 Jan 16].
Available from: https://ir.lib.uwo.ca/etd/511.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Booth WJ. Reductions in Muscle Quantity and Quality in Old and Very Old Men: New Insights into the Progression of Sarcopenia. [Thesis]. University of Western Ontario; 2012. Available from: https://ir.lib.uwo.ca/etd/511
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
20.
WONG CHUN KIT.
IMPLEMENTATION, OPTIMIZATION, AND APPLICATION OF QUANTITATIVE MAGNETIZATION TRANSFER RATIO (QMTR).
Degree: 2016, National University of Singapore
URL: http://scholarbank.nus.edu.sg/handle/10635/132134
Subjects/Keywords: quantitative magnetization transfer; qMT; qMTR; MTR; MRI; quantitative MRI
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
KIT, W. C. (2016). IMPLEMENTATION, OPTIMIZATION, AND APPLICATION OF QUANTITATIVE MAGNETIZATION TRANSFER RATIO (QMTR). (Thesis). National University of Singapore. Retrieved from http://scholarbank.nus.edu.sg/handle/10635/132134
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
KIT, WONG CHUN. “IMPLEMENTATION, OPTIMIZATION, AND APPLICATION OF QUANTITATIVE MAGNETIZATION TRANSFER RATIO (QMTR).” 2016. Thesis, National University of Singapore. Accessed January 16, 2021.
http://scholarbank.nus.edu.sg/handle/10635/132134.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
KIT, WONG CHUN. “IMPLEMENTATION, OPTIMIZATION, AND APPLICATION OF QUANTITATIVE MAGNETIZATION TRANSFER RATIO (QMTR).” 2016. Web. 16 Jan 2021.
Vancouver:
KIT WC. IMPLEMENTATION, OPTIMIZATION, AND APPLICATION OF QUANTITATIVE MAGNETIZATION TRANSFER RATIO (QMTR). [Internet] [Thesis]. National University of Singapore; 2016. [cited 2021 Jan 16].
Available from: http://scholarbank.nus.edu.sg/handle/10635/132134.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
KIT WC. IMPLEMENTATION, OPTIMIZATION, AND APPLICATION OF QUANTITATIVE MAGNETIZATION TRANSFER RATIO (QMTR). [Thesis]. National University of Singapore; 2016. Available from: http://scholarbank.nus.edu.sg/handle/10635/132134
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Freie Universität Berlin
21.
Bobowski, Kamil Nick.
Magnetization Dynamics in the Lanthanide Metal Gadolinium.
Degree: 2020, Freie Universität Berlin
URL: http://dx.doi.org/10.17169/refubium-27906
► In this thesis we investigate the rare-earth metal Gd aiming to gain more insight into the complex interplay of physical processes leading to optically induced…
(more)
▼ In this thesis we investigate the rare-earth metal Gd aiming to gain more insight into the complex interplay of physical processes leading to optically induced ultrafast
magnetization dynamics. Using X-ray magnetic circular dichroism (XMCD) we study the
magnetization dynamics in Gd over a wide range of time scales and pump laser fluences, while using photoemission spectroscopy (PES) we focus on the first 100 fs of the dynamics showing an increase in exchange splitting of the 5d6s bulk bands. Moreover, we analyze oscillations in the kinetic energy of the photoemitted electrons for negative pump-probe delays in our PES data.
Using XMCD in reflection we find a two-step demagnetization on sub-ps and tens of ps time scales with a remagnetization on a hundred ps time scale for various pump laser fluences. An extended version of the microscopic three-temperature model (M3TM) captures the dynamics of the whole data set and suggests Elliott-Yafet-type spin-flip scattering to play a dominant role in the 100 fs to ns
magnetization dynamics in Gd. On the fast time scale the demagnetization magnitude depends exponentially on the pump laser fluence implying that a complete demagnetization on that time scale in pure Gd is not physically possible. Results for varying pump photon energies indicate an influence of the initial hot electron distribution on the following dynamics, where lower pump photon energies cause a weaker demagnetization in the early sub-ps dynamics. Our PES study reveals new results particularly in the first 100 fs, where the majority-spin bulk band reacts directly to laser excitation and is not delayed as found in literature. Shifts in the minority- and majority-spin bulk band binding energies lead to a surprising increase in exchange splitting of the 5d6s valence bands in Gd for a few dozen fs after laser excitation indicating an increase in
magnetization. Concurrently, the majority-spin bulk and surface states shift in opposing directions despite the same spin polarization. We find optically induced spin
transfer (OISTR) between the surface and bulk states in Gd likely to account for this phenomenon.
At negative pump-probe delays we observe oscillations in the kinetic energy of photoemitted electrons, a phenomenon explained in literature by ponderomotive acceleration by a transient grating formed by the interference of the incoming and reflected pump laser pulse. We observe a strong enhancement of the oscillation amplitudes on Gd in accordance with the model. We find similar oscillations on W and model parameters show the expected pump photon energy dependence. However, we see different amplitudes for electrons emitted out of different states in W with only slightly different kinetic energy, an unexpected result since photoemitted, free electrons
subject to the same potential should experience the same force.
Advisors/Committee Members: male (gender), Weinelt, Martin (firstReferee), Ernstorfer, Ralph (furtherReferee).
Subjects/Keywords: Ultrafast magnetization dynamics; Gadolinium; Electron dynamics; Optically induced spin transfer; Ponderomotive oscillations; X-ray magnetic circular dichroism; Photoemission spectroscopy; ddc:538
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Bobowski, K. N. (2020). Magnetization Dynamics in the Lanthanide Metal Gadolinium. (Thesis). Freie Universität Berlin. Retrieved from http://dx.doi.org/10.17169/refubium-27906
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Bobowski, Kamil Nick. “Magnetization Dynamics in the Lanthanide Metal Gadolinium.” 2020. Thesis, Freie Universität Berlin. Accessed January 16, 2021.
http://dx.doi.org/10.17169/refubium-27906.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Bobowski, Kamil Nick. “Magnetization Dynamics in the Lanthanide Metal Gadolinium.” 2020. Web. 16 Jan 2021.
Vancouver:
Bobowski KN. Magnetization Dynamics in the Lanthanide Metal Gadolinium. [Internet] [Thesis]. Freie Universität Berlin; 2020. [cited 2021 Jan 16].
Available from: http://dx.doi.org/10.17169/refubium-27906.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Bobowski KN. Magnetization Dynamics in the Lanthanide Metal Gadolinium. [Thesis]. Freie Universität Berlin; 2020. Available from: http://dx.doi.org/10.17169/refubium-27906
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Oulu
22.
Rantaharju, J. (Jyrki).
Magnetization dynamics in paramagnetic systems.
Degree: 2018, University of Oulu
URL: http://urn.fi/urn:isbn:9789526221205
► Abstract This thesis reports simulations of direct observables in electron and nuclear spin relaxation experiments in an example paramagnetic system, as well as polarization transfer…
(more)
▼ Abstract
This thesis reports simulations of direct observables in electron and nuclear spin relaxation experiments in an example paramagnetic system, as well as polarization transfer occurring in a spin-exchange optical pumping (SEOP) experiment. Studies of paramagnetic relaxation are important, e.g., in the development of agents used for enhanced contrast in magnetic resonance imaging. SEOP is used to produce hyperpolarized noble gases, which are then used to, e.g., enhance sensitivity in structural studies of matter with nuclear magnetic resonance. Presently the theory, available software and hardware for such computational modeling have reached a state in which quantitative reproduction of the experimentally observed magnetization decay is possible from first principles.
The present multiscale computations are carried out from first principles combining molecular dynamics simulations of atomistic motion and quantum-chemical electronic structure calculations of the spin interaction parameters that enter the effective spin Hamiltonian. A time series of the spin Hamiltonian is then explicitly used to propagate spin dynamics in the system, and dynamical time constants of the magnetization are obtained through ensemble averaging. The complete decay of electron spin magnetization could be followed directly within the duration of the simulation, whereas the nuclear spin relaxation rates were extracted using Kubo’s theory regarding generalized cumulant expansion and stochastic processes.
The extracted electron and nuclear spin relaxation rates for the chosen prototypic system, the aqueous solution of Ni²⁺, are in quantitative and semi-quantitative agreement, respectively, with the available experimental results. The simulations of polarization transfer corroborate the empirical observations on the importance of van der Waals complexes and binary collisions in the spin-exchange process. Long van der Waals complexes represent the overwhelmingly most significant kind of individual events, but the short binary collisions can also give a relatively important contribution due to their vast abundance. This thesis represents a first study in which first principles-calculated trajectories of individual events could be followed.
The simulations reported in this thesis were run without any empirical parametrization and thus represent a significant step in first-principles computational modeling of magnetization dynamics.
Subjects/Keywords: electron spin relaxation; generalized cumulant expansion; hyperpolarization; magnetization dynamics; multiscale modeling; nuclear spin relaxation; paramagnetic nuclear magnetic resonance; polarization transfer; spin-exchange optical pumping; stochastic process
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APA (6th Edition):
Rantaharju, J. (. (2018). Magnetization dynamics in paramagnetic systems. (Doctoral Dissertation). University of Oulu. Retrieved from http://urn.fi/urn:isbn:9789526221205
Chicago Manual of Style (16th Edition):
Rantaharju, J (Jyrki). “Magnetization dynamics in paramagnetic systems.” 2018. Doctoral Dissertation, University of Oulu. Accessed January 16, 2021.
http://urn.fi/urn:isbn:9789526221205.
MLA Handbook (7th Edition):
Rantaharju, J (Jyrki). “Magnetization dynamics in paramagnetic systems.” 2018. Web. 16 Jan 2021.
Vancouver:
Rantaharju J(. Magnetization dynamics in paramagnetic systems. [Internet] [Doctoral dissertation]. University of Oulu; 2018. [cited 2021 Jan 16].
Available from: http://urn.fi/urn:isbn:9789526221205.
Council of Science Editors:
Rantaharju J(. Magnetization dynamics in paramagnetic systems. [Doctoral Dissertation]. University of Oulu; 2018. Available from: http://urn.fi/urn:isbn:9789526221205

Universidade do Rio Grande do Sul
23.
Accioly, Artur Difini.
Transferência de spin em nanopilares magnéticos : caos e ressonância estocástica.
Degree: 2015, Universidade do Rio Grande do Sul
URL: http://hdl.handle.net/10183/129999
► Ao passar por uma fina camada magnética uma corrente spin polarizada pode produzir um efeito de torque clássico atuando na camada, sendo capaz de gerar…
(more)
▼ Ao passar por uma fina camada magnética uma corrente spin polarizada pode produzir um efeito de torque clássico atuando na camada, sendo capaz de gerar precessão e reversão da magnetização. Esse efeito tem sido alvo de inúmeras pesquisas, em especial pela possibilidade de aplicações em memórias magnéticas não voláteis e em nano-osciladores de alta frequência, entretanto outras características podem ser exploradas. Em particular, devido ao seu caráter não-linear, torques de spin aplicados em camadas magnéticas podem fornecer condições para aparecimento de caos determinístico e ressonância estocástica. Caos determinístico pode ocorrer em sistemas dinâmicos contínuos que tenham ao menos três graus de liberdade. Nesse caso, mesmo que apenas termos determinísticos sejam considerados, a combinação de termos não-lineares e alta sensibilidade em relação a condições iniciais ou pequenas perturbações pode gerar irregularidade e imprevisibilidade no sistema. Ressonância estocástica é o nome que se dá para fenômenos em que a adição de ruído a um sistema pode melhorar a resposta do mesmo, existindo um nível ótimo de ruído. Esse fenômeno pode ser usado para detecção e amplificação de sinais de baixa intensidade, por exemplo. Aqui analisamos a dinâmica da magnetização da camada livre de junções magnéticas em geometrias do tipo nanopilar, com o estudo dividido em dinâmicas determinísticas e estocásticas. Dentro da análise apenas com termos determinísticos, buscamos verificar comportamentos regulares, irregulares e caóticos, caracterizando o sistema através da geração de diagramas com as fases dinâmicas para diferentes valores de parâmetros. Foram vistas duas geometrias diferentes, sendo que em uma delas foi possível fazer a caracterização completa das fases dinâmicas do sistema. No caso de dinâmicas estocásticas, buscamos explorar efeitos não-lineares e flutuações térmicas, analisando ressonância estocástica e sincronização facilitada por ruído em uma junção túnel magnética, além de estudar as respostas dinâmicas quando há apenas o torque de Slonczewski e quando também está presente o torque tipo campo. Foi possível observar a influência de diversos parâmetros, como a amplitude da corrente aplicada e a frequência de entrada, na resposta magnética e na sincronização de dispositivos estocásticos. Além disso, vimos que com a inclusão do torque tipo campo aparece um possível novo comportamento, similar à ressonância, em alta frequência, ainda não detectado experimentalmente. Esses resultados são importantes pela possibilidade de uso desses dispositivos spintrônicos em transmissão segura de dados, comunicação em alta frequência e em uma nova geração de dispositivos bio-inspirados e eficientes energeticamente.
When passing through a fine magnetic layer a spin polarized electric current may result in a classical torque acting on the layer, being capable of causing magnetization precession and reversal. This effect has been object of numerous researches, specially because of possible applications in non-volatile magnetic memories and…
Advisors/Committee Members: Pereira, Luis Gustavo.
Subjects/Keywords: Magnetização; Spin transfer; Magnetorresistência; Spin torques; Densidade de corrente; Magnetization dynamics; Magnetic junctions; Torque; Sistemas estocásticos; Nanopillars; Nonlinear dynamics; Tunelamento magnético; Stochastic resonance; Dinamica nao-linear; Spin; Chaos; Caos; Osciladores
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Accioly, A. D. (2015). Transferência de spin em nanopilares magnéticos : caos e ressonância estocástica. (Thesis). Universidade do Rio Grande do Sul. Retrieved from http://hdl.handle.net/10183/129999
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Accioly, Artur Difini. “Transferência de spin em nanopilares magnéticos : caos e ressonância estocástica.” 2015. Thesis, Universidade do Rio Grande do Sul. Accessed January 16, 2021.
http://hdl.handle.net/10183/129999.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Accioly, Artur Difini. “Transferência de spin em nanopilares magnéticos : caos e ressonância estocástica.” 2015. Web. 16 Jan 2021.
Vancouver:
Accioly AD. Transferência de spin em nanopilares magnéticos : caos e ressonância estocástica. [Internet] [Thesis]. Universidade do Rio Grande do Sul; 2015. [cited 2021 Jan 16].
Available from: http://hdl.handle.net/10183/129999.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Accioly AD. Transferência de spin em nanopilares magnéticos : caos e ressonância estocástica. [Thesis]. Universidade do Rio Grande do Sul; 2015. Available from: http://hdl.handle.net/10183/129999
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Université de Grenoble
24.
Merodio Camara, Pablo.
Spin dependent transport in antiferro and ferrimagnetic nanostructures : Transport dépendant du spin dans des nanostructures antiferro et ferrimagnétiques.
Degree: Docteur es, Physique de la matière condensée et du rayonnement, 2014, Université de Grenoble
URL: http://www.theses.fr/2014GRENY072
► En électronique de spin, le couple de transfert de spin (STT) et la magnétorésistance tunnel (TMR) dans les jonctions tunnel magnétiques à électrodes ferromagnétiques (F)…
(more)
▼ En électronique de spin, le couple de transfert de spin (STT) et la magnétorésistance tunnel (TMR) dans les jonctions tunnel magnétiques à électrodes ferromagnétiques (F) sont deux phénomènes physiques essentiels. Dans cette thèse, nous présentons une étude théorique du STT dans des jonctions tunnel antiferromagnétiques (AF), où deux électrodes non-plus F mais AF sont séparées par une barrière isolante non-magnétique. Plus concrètement, les comportements du STT et de la TMR sont étudiés dans des jonctions tunnel AF cristallines, et ce, à l´aide de calculs de liaisons fortes dans le cadre du formalisme de Keldysh. Nous avons observé une distribution spatiale de la composante perpendiculaire du STT régulière et de signe alternatif, ce qui est similaire au comportement de la composante parallèle. Ces variations spatiales de la composante perpendiculaire sont cependant spécifiques à l'utilisation d'une barrière tunnel et contrastent avec les effets observés par le passé pour le cas de couches séparatrices métalliques. De plus, contrairement aux jonctions tunnel F conventionnelles, nous avons montré que la TMR peut augmenter avec la tension appliquée et atteindre des valeurs du même ordre de grandeur que pour des vannes de spin usuelles : tout-métallique et à électrodes F.L´analyse effectuée pour des AF est ensuite étendue aux matériaux ferrimagnétiques (FI), pour lesquels les AF constituent, somme toute, des cas limites. La complexité magnétique additionnelle inhérente aux FI se traduit par un comportement spatial du STT beaucoup plus riche dans les jonctions tunnel FI. Nous observons notamment que les paramètres électroniques tels que les largeurs et les décalages de bandes ont une très forte influence sur le STT. Plus particulièrement, la différence entre les couplages d'échange inter-spin locaux des deux sous-réseaux du FI donne lieu à une distribution spatiale du STT ondulatoire qui est modulée par la densité locale de spin. Il est possible d'ajuster cet effet en jouant sur la tension appliquée aux bornes de la jonction tunnel FI. Nous trouvons de plus que la différence entre les couplages d'échange inter-spin locaux constitue un paramètre fondamental pour la quantification des longueurs caractéristiques du STT dans les FIs. Ce paramètre peut être considéré comme un champ d´échange effectif, par similitude avec le cas usuel des Fs qui présentent un champ d´échange homogène.Pour finir, nous avons sondé expérimentalement les longueurs caractéristiques du STT dans des AFs. Pour de l'Ir20Mn80 et du Fe50Mn50, nous avons déterminé les longueurs de pénétration de spin et les mécanismes d'absorption de courants de spin à température ambiante en utilisant la résonance F et le pompage de spin. Plus précisément, nous avons associé les profondeurs de pénétration critiques à deux mécanismes d'absorption distincts: du déphasage pour l´Ir20Mn80 et du retournement de spin pour le Fe50Mn50.
Spin transfer torque (STT) and tunnelling magnetoresistance (TMR) in magnetic tunnel junctions with ferromagnetic (F) leads are two essential…
Advisors/Committee Members: Chshiev, Mairbek (thesis director), Baltz, Vincent (thesis director), Béa, Hélène (thesis director).
Subjects/Keywords: Couple de transfert de spin; Multicouches magnetiques; Spintronique; Magnétorésistance; Dynamique de l’aimantation; Spin pumping; Spin torque/spin transfer effect; Magnetic multilayers; Spintronics; Magnetoresistance; Magnetization dynamics; Spin pumping; 530
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Merodio Camara, P. (2014). Spin dependent transport in antiferro and ferrimagnetic nanostructures : Transport dépendant du spin dans des nanostructures antiferro et ferrimagnétiques. (Doctoral Dissertation). Université de Grenoble. Retrieved from http://www.theses.fr/2014GRENY072
Chicago Manual of Style (16th Edition):
Merodio Camara, Pablo. “Spin dependent transport in antiferro and ferrimagnetic nanostructures : Transport dépendant du spin dans des nanostructures antiferro et ferrimagnétiques.” 2014. Doctoral Dissertation, Université de Grenoble. Accessed January 16, 2021.
http://www.theses.fr/2014GRENY072.
MLA Handbook (7th Edition):
Merodio Camara, Pablo. “Spin dependent transport in antiferro and ferrimagnetic nanostructures : Transport dépendant du spin dans des nanostructures antiferro et ferrimagnétiques.” 2014. Web. 16 Jan 2021.
Vancouver:
Merodio Camara P. Spin dependent transport in antiferro and ferrimagnetic nanostructures : Transport dépendant du spin dans des nanostructures antiferro et ferrimagnétiques. [Internet] [Doctoral dissertation]. Université de Grenoble; 2014. [cited 2021 Jan 16].
Available from: http://www.theses.fr/2014GRENY072.
Council of Science Editors:
Merodio Camara P. Spin dependent transport in antiferro and ferrimagnetic nanostructures : Transport dépendant du spin dans des nanostructures antiferro et ferrimagnétiques. [Doctoral Dissertation]. Université de Grenoble; 2014. Available from: http://www.theses.fr/2014GRENY072

Vanderbilt University
25.
Ou, Xiawei.
Quantitative magnetization transfer imaging techniques and applications.
Degree: PhD, Physics, 2007, Vanderbilt University
URL: http://hdl.handle.net/1803/14808
► This dissertation discusses magnetization transfer effects in magnetic resonance imaging and the development and applications of quantitative magnetization transfer imaging techniques. Specifically, the magnetization transfer…
(more)
▼ This dissertation discusses
magnetization transfer effects in magnetic resonance imaging and the development and applications of quantitative
magnetization transfer imaging techniques. Specifically, the
magnetization transfer effects in single slice spoiled gradient echo imaging are investigated; state-of-the-art quantitative
magnetization transfer imaging techniques are presented and compared; the sensitivity and specificity of quantitative
magnetization imaging are tested and demonstrated by imaging various animal models with central nervous system diseases.
Advisors/Committee Members: John C. Gore (committee member), Adam W. Anderson (committee member), Mark D. Does (committee member), Norman H. Tolk (committee member), Daniel Frank Gochberg (Committee Chair).
Subjects/Keywords: diffusion tensor imaging; quantitative magnetization transfer; magnetic resonance imaging; myelin; central nervous system
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
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APA (6th Edition):
Ou, X. (2007). Quantitative magnetization transfer imaging techniques and applications. (Doctoral Dissertation). Vanderbilt University. Retrieved from http://hdl.handle.net/1803/14808
Chicago Manual of Style (16th Edition):
Ou, Xiawei. “Quantitative magnetization transfer imaging techniques and applications.” 2007. Doctoral Dissertation, Vanderbilt University. Accessed January 16, 2021.
http://hdl.handle.net/1803/14808.
MLA Handbook (7th Edition):
Ou, Xiawei. “Quantitative magnetization transfer imaging techniques and applications.” 2007. Web. 16 Jan 2021.
Vancouver:
Ou X. Quantitative magnetization transfer imaging techniques and applications. [Internet] [Doctoral dissertation]. Vanderbilt University; 2007. [cited 2021 Jan 16].
Available from: http://hdl.handle.net/1803/14808.
Council of Science Editors:
Ou X. Quantitative magnetization transfer imaging techniques and applications. [Doctoral Dissertation]. Vanderbilt University; 2007. Available from: http://hdl.handle.net/1803/14808

Vanderbilt University
26.
Dula, Adrienne Nicole.
Micro-anatomical characterization of central white matter using magnetic resonance imaging.
Degree: PhD, Biomedical Engineering, 2008, Vanderbilt University
URL: http://hdl.handle.net/1803/12177
► Most magnetic resonance imaging techniques offer tissue contrast but provide limited information regarding the variation of the magnetic resonance signal that exists on a smaller…
(more)
▼ Most magnetic resonance imaging techniques offer tissue contrast but provide limited information regarding the variation of the magnetic resonance signal that exists on a smaller scale. The magnetic resonance signal arising from a heterogeneous tissue, such as spinal cord white matter, is the sum of signals from each tissue compartment within the imaging voxel. Analysis of this signal can better characterize the micro-anatomical heterogeneity tissue, white matter in particular. Many questions remain with regard to the compartmental contributions for the various types of magnetic resonance imaging (MRI) contrast. This project utilizes a variety of in vitro studies as well as simulations to better characterize the contribution of different water compartments to conventional MRI methods. Such an understanding of the complex combination of the various relaxation and exchange properties is important in developing an anatomical basis for interpreting
magnetization transfer and T2 weighted images, particularly with respect to myelination.
Advisors/Committee Members: Bill Valentine (committee member), Adam Anderson (committee member), Dan Gochberg (committee member), John Gore (committee member), Dr. Mark Does (Committee Chair).
Subjects/Keywords: quantitative magnetization transfer; multiexponential T2; Spinal cord – Magnetic resonance imaging; myelin; Myelination
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Dula, A. N. (2008). Micro-anatomical characterization of central white matter using magnetic resonance imaging. (Doctoral Dissertation). Vanderbilt University. Retrieved from http://hdl.handle.net/1803/12177
Chicago Manual of Style (16th Edition):
Dula, Adrienne Nicole. “Micro-anatomical characterization of central white matter using magnetic resonance imaging.” 2008. Doctoral Dissertation, Vanderbilt University. Accessed January 16, 2021.
http://hdl.handle.net/1803/12177.
MLA Handbook (7th Edition):
Dula, Adrienne Nicole. “Micro-anatomical characterization of central white matter using magnetic resonance imaging.” 2008. Web. 16 Jan 2021.
Vancouver:
Dula AN. Micro-anatomical characterization of central white matter using magnetic resonance imaging. [Internet] [Doctoral dissertation]. Vanderbilt University; 2008. [cited 2021 Jan 16].
Available from: http://hdl.handle.net/1803/12177.
Council of Science Editors:
Dula AN. Micro-anatomical characterization of central white matter using magnetic resonance imaging. [Doctoral Dissertation]. Vanderbilt University; 2008. Available from: http://hdl.handle.net/1803/12177
27.
Mchinda, Samira.
Optimisation théorique et expérimentale de la technique IRM du transfert d’aimantation inhomogène pour l’imagerie de la myéline : application à la sclérose en plaques : Theorical and experimental optimisation of the inhomogeneous magnetization transfer MRI technique for myelin imaging : application in multiple sclerosis.
Degree: Docteur es, Neurosciences, 2019, Aix Marseille Université
URL: http://www.theses.fr/2019AIXM0378
► La technique ihMT permet d’isoler de manière sélective le signal associé à certaines macromolécules en exploitant les processus de couplage dipolaire dont elles font l’objet,…
(more)
▼ La technique ihMT permet d’isoler de manière sélective le signal associé à certaines macromolécules en exploitant les processus de couplage dipolaire dont elles font l’objet, sur la base de leur durée de vie caractérisée par le temps de relaxation dipolaire, T1D. Les valeurs de T1D relativement longues dans les structures myélinisées permettent d’obtenir des images sélectives de la myéline. L’objectif de cette thèse est le développement de séquences IRM ihMT 3D optimisées en termes de sensibilité à la myéline, membrane essentielle à la conduction de l’influx nerveux, en vue d’une application en clinique. Pour cela, nous avons développé des modèles physiques (calculs numériques avec Matlab) basés sur la théorie de saturation des spins dans les solides, qui décrivent l’évolution du signal ihMT au cours du temps en fonction des paramètres tissulaires et de paramètres de séquences IRM cliniques réalistes. Nous avons avec l’appui du modèle implémenté une séquence ihMT 3D optimisée sur un scanner IRM 1,5T. Les paramètres optimaux ont permis d’aboutir à un protocole haute résolution du cerveau entier, qui présente une sensibilité accrue aux structures myélinisées. Puis nous avons étendu ce travail d’optimisation à 3T ; ce qui a permis d’obtenir un protocole hautement résolu du cerveau entier, sensible aux structures myélinisées et avec une sensibilité réduite aux inhomogénéités de champ B1. Afin de valider la technique ihMT comme biomarqueur de la myéline, nous avons appliqué la séquence optimisée à 1,5T sur une cohorte de patients atteints de SEP, et nous avons évalué sa capacité à suivre au cours du temps les processus de démyélinisation et de remyélinisation spontanées..
The ihMT technique selectively isolates the signal associated with certain macromolecules by exploiting the dipolar coupling processes to which they are subjected, on the basis of their lifetime characterized by the dipolar relaxation time, T1D. The relatively long T1D values in myelinated structures provide selective images of myelin. The objective of this thesis is the development of ihMT 3D MRI sequences optimized in terms of sensitivity to myelin,which is an essential membrane for nerve impulse conduction, for clinical application. To achieve it, we first developed physical models (numerical calculations with Matlab) based on the theory of saturation of spins in solids, which describe the evolution of the ihMT signal over time as a function of tissue parameters and for realistic parameters of clinical MRI sequences.. Using this theoretical model, we then optimized a 3D ihMT sequence on a 1.5T MRI scanner. The optimal parameters resulted in a high-resolution protocol of the whole brain, with increased sensitivity to myelinated structures. Then we extended this optimization work at 3T. Optimal parameters at 3T also resulted in a high-resolution protocol for the whole brain, with a trade-off between high sensitivity to myelinated structures and reduced sensitivity to B1 field inhomogeneities. In order to validate the ihMT technique as a myelin…
Advisors/Committee Members: Duhamel, Guillaume (thesis director), Girard, Olivier (thesis director).
Subjects/Keywords: Irm; Transfert d’aimantation inhomogène (ihMT); Couplage dipolaire; Myéline; Sclérose en plaques (SEP); Mri; Inhomogeneous Magnetization Transfer (ihMT); Dipolar coupling; Myelin; Multiple sclerosis (MS)
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Mchinda, S. (2019). Optimisation théorique et expérimentale de la technique IRM du transfert d’aimantation inhomogène pour l’imagerie de la myéline : application à la sclérose en plaques : Theorical and experimental optimisation of the inhomogeneous magnetization transfer MRI technique for myelin imaging : application in multiple sclerosis. (Doctoral Dissertation). Aix Marseille Université. Retrieved from http://www.theses.fr/2019AIXM0378
Chicago Manual of Style (16th Edition):
Mchinda, Samira. “Optimisation théorique et expérimentale de la technique IRM du transfert d’aimantation inhomogène pour l’imagerie de la myéline : application à la sclérose en plaques : Theorical and experimental optimisation of the inhomogeneous magnetization transfer MRI technique for myelin imaging : application in multiple sclerosis.” 2019. Doctoral Dissertation, Aix Marseille Université. Accessed January 16, 2021.
http://www.theses.fr/2019AIXM0378.
MLA Handbook (7th Edition):
Mchinda, Samira. “Optimisation théorique et expérimentale de la technique IRM du transfert d’aimantation inhomogène pour l’imagerie de la myéline : application à la sclérose en plaques : Theorical and experimental optimisation of the inhomogeneous magnetization transfer MRI technique for myelin imaging : application in multiple sclerosis.” 2019. Web. 16 Jan 2021.
Vancouver:
Mchinda S. Optimisation théorique et expérimentale de la technique IRM du transfert d’aimantation inhomogène pour l’imagerie de la myéline : application à la sclérose en plaques : Theorical and experimental optimisation of the inhomogeneous magnetization transfer MRI technique for myelin imaging : application in multiple sclerosis. [Internet] [Doctoral dissertation]. Aix Marseille Université 2019. [cited 2021 Jan 16].
Available from: http://www.theses.fr/2019AIXM0378.
Council of Science Editors:
Mchinda S. Optimisation théorique et expérimentale de la technique IRM du transfert d’aimantation inhomogène pour l’imagerie de la myéline : application à la sclérose en plaques : Theorical and experimental optimisation of the inhomogeneous magnetization transfer MRI technique for myelin imaging : application in multiple sclerosis. [Doctoral Dissertation]. Aix Marseille Université 2019. Available from: http://www.theses.fr/2019AIXM0378

Freie Universität Berlin
28.
Alekhin, Alexandr.
Ultraschnelle Magnetisierungsdynamik durch Transport heißer Ladungträger.
Degree: 2016, Freie Universität Berlin
URL: http://dx.doi.org/10.17169/refubium-12139
► Diese Arbeit umfasst die Untersuchung der ultraschnellen Magnetisierungsdynamik durch Transport heißer Ladungträger (HC) in metallischen Multilayer(ML)-Strukturen anhand zeitaufgelöster linearer und nichtlinearer optischer Femtosekundenspektroskopie. Der lineare…
(more)
▼ Diese Arbeit umfasst die Untersuchung der ultraschnellen
Magnetisierungsdynamik durch Transport heißer Ladungträger (HC) in
metallischen Multilayer(ML)-Strukturen anhand zeitaufgelöster linearer und
nichtlinearer optischer Femtosekundenspektroskopie. Der lineare magneto-
optische Kerr-Effekt (MOKE) und die magnetisch induzierte Erzeugung der
zweiten Harmonischen (mSHG) wurden verwendet, um lichtinduzierte Spindynamik
in hoch angeregten Zuständen der Materie mit 20 Femtosekunden (fs)
Zeitauflösung zu untersuchen, was den Zeitskalen zugrundeliegender
Elementarprozesse in Metallen entspricht. Der Spintransfer von einem
Ferromagneten zu einem Edelmetall, oder von einem Ferromagneten zum anderen
Ferromagneten mittels HC-Transport durch eine nichtmagnetische Zwischenschicht
hindurch ist von besonderem Interesse in dieser Arbeit. Untersuchungen dieser
Effekte sind von großer Bedeutung für das Verständnis der ultraschnellen
Spindynamik, und die gewonnenen Erkenntnisse haben möglicherweise einen großen
Einfluss auf zukünftige Spintronik-Geräte. Als Modellsysteme wurden
epitaktische Au/Fe/MgO(001) und Fe/Au/Fe/MgO(001) Strukturen verwendet, wobei
im letztgenannten Fall eine Fe-Schicht als Spinemitter und die andere Fe-
Schicht als Spinkollektor dient. Als erster Schritt zum Verständnis des Spin-
Transfers in metallischen MLs, wurde der HC Transport in einfachen
Zweischicht-Au/Fe/MgO(001)-strukturen untersucht. Es wurde gezeigt, dass die
optische Anregung von Fe zur Erzeugung eines Spin-Stroms führt, der von der
ferromagnetischen Schicht in die nicht-magnetische Schicht fließt. Dieses
Phänomen ist ein Analogon zum Spin-Seebeck-Effekt, wobei in diesem Fall der
Spin-Strom in Gold von nicht-gleichgewichts HCs dominiert wird, die sich im
quasi-ballistichen Regime bewegen. Die quantitative Analyse der MOKE Signalen,
die von der Fe-Seite der Au/Fe/MgO(001)-Strukturen mit unterschiedlichen Fe-
Dicken gemessen wurden, zeigt den bemerkbaren Beitrag des HC-Transports zur
ultraschnellen Entmagnetisierung des Fe-Films, gefolgt von einer
vorübergehenden Magnetisierung der Au-Schicht, die zusätzlich zum MOKE Signal
beiträgt. Abschließend wurde Magnetisierungsdynamik, die in einem
Ferromagneten mittels der Injektion von spinpolarisierten HCs induziert wird,
an Dreischicht-Fe/Au/Fe/MgO(001)-strukturen untersucht. Aufgrund
unterschiedlicher Koerzitiv-kräfte in den Fe-Filmen können die
Magnetisierungen im Spinemitter und im Spinkollektor parallel, antiparallel
oder orthogonal zueinander ausgerichtet werden. In der orthogonalen
Ausrichtung zeigt es sich, dass der optisch erzeugte Spinstrompuls stehende
Spinwellen im Spinkollektor erzeugt, die durch das räumlich inhomogen Spin-
Transfer-Drehmoment (STT) induziert werden. Die Realisierung verschiedener
gegenseitigen Orientierungen der äußeren Magnetfeldes und der Magnetisierungen
im Spin-emitter und im Spin-kollektor ermöglicht es, das Signal des STT
unabhängig vom Signal der laserinduzierter Erwärmung der Probe zu messen.
Außerdem in der Analyse der mSHG-Antwort, die in verschiedenen magnetischen…
Advisors/Committee Members: [email protected] (contact), [email protected] (contact), m (gender), Prof. Dr. Martin Wolf (firstReferee), Prof. Dr. Martin Weinelt (furtherReferee).
Subjects/Keywords: ultrafast spin transport; magnetization dynamics; nonlinear optics; optical pump-probe experiment; spin transfer torque.; 500 Naturwissenschaften und Mathematik::530 Physik::530 Physik; 500 Naturwissenschaften und Mathematik::530 Physik::538 Magnetismus
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Alekhin, A. (2016). Ultraschnelle Magnetisierungsdynamik durch Transport heißer Ladungträger. (Thesis). Freie Universität Berlin. Retrieved from http://dx.doi.org/10.17169/refubium-12139
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Alekhin, Alexandr. “Ultraschnelle Magnetisierungsdynamik durch Transport heißer Ladungträger.” 2016. Thesis, Freie Universität Berlin. Accessed January 16, 2021.
http://dx.doi.org/10.17169/refubium-12139.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Alekhin, Alexandr. “Ultraschnelle Magnetisierungsdynamik durch Transport heißer Ladungträger.” 2016. Web. 16 Jan 2021.
Vancouver:
Alekhin A. Ultraschnelle Magnetisierungsdynamik durch Transport heißer Ladungträger. [Internet] [Thesis]. Freie Universität Berlin; 2016. [cited 2021 Jan 16].
Available from: http://dx.doi.org/10.17169/refubium-12139.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Alekhin A. Ultraschnelle Magnetisierungsdynamik durch Transport heißer Ladungträger. [Thesis]. Freie Universität Berlin; 2016. Available from: http://dx.doi.org/10.17169/refubium-12139
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Université de Bordeaux I
29.
Gutium Ababei, Rodica.
Synthèses et études de nouveaux matériaux magnétiques et photomagnétiques : What sociology for which democracy? : political rationality and emancipation.
Degree: Docteur es, Physico-Chimie de la Matière Condensée, 2011, Université de Bordeaux I
URL: http://www.theses.fr/2011BOR14238
► Le développement récent de l’électronique exige la mise au point de composants de plus en plus efficaces, de plus en plus rapides et de plus…
(more)
▼ Le développement récent de l’électronique exige la mise au point de composants de plus en plus efficaces, de plus en plus rapides et de plus en plus réduits en taille. Dès les années 1970, il a été montré que l'on pourrait utiliser la molécule comme composante électronique élémentaire. Dans ce domaine, le chimiste sait aujourd’hui créer des molécules douées de propriétés remarquables, comme par exemple les molécules-aimants et les chaines-aimants qui montrent une bistabilité magnétique à basse température (T < 10 K) liée à la relaxation lente de leur aimantation, leur conférant ainsi la capacité de conserver l’information. Dans ce contexte, l’idée d’organiser des molécules-aimants par des connecteurs moléculaires photocommutables permet à la fois d’ajouter une propriété magnétique supplémentaire au matériau, mais également de photo-contrôler la bistabilité magnétique de ces objets. Dans ces travaux de thèse, nous nous sommes intéressés à l’association de molécules-aimants avec deux types de liens : les complexes à transfert de charge Na2[Fe(CN)5NO] et à conversion de spin [Fe(LN5)(CN)2] et [Fe(LN3O2)(CN)2] (LN5 et LN3O2 étant des ligands pentadentes) dans le but de photo-contrôler les propriétés magnétiques. Les résultats obtenus dans la partie dédiée à l’organisation des complexes [MnIII(BS)]+ via le précurseur photo-actif nitroprussiate se sont révélés décevants du point de vue photomagnétisme. Toutefois, un des nouveaux composés 2D présente un comportement magnétique de type molécule-aimant. La stratégie de connecter les précurseurs de [MnIII(BS)]+par des complexes photomagnétiques [Fe(LN3O2)(CN)2] et [Fe(LN5)(CN)2] pour synthétiser de nouveaux systèmes photosensibles a porté ces fruits puisque neuf nouveaux systèmes ont été synthétisés. Permi les résultats les plus significatifs, nous avons obtenu un système unidimensionnel dans lequel les unité dimères [MnIII2(BS)2]2+ sont connectées par l’entité photomagnétique et qui présente un comportement de molécule-aimant. On retiendra aussi un autre système unidimentionnel qui présente un ordre antiferromagnétique et de la relaxation lente de l’aimantation. D’autre part, les études photomagnétiques ont clairement montré des comportements photoinduits pour les cinq composés qui contiennent les centres FeII à l’état bas spin. Pour conclure, le développement de notre stratégie est prometteur pour la création de nouveaux matériaux photomagnétiques dans les années à venir.
The exponential growth of technological demands for information storage capacity is at the origin of the nanosciences and the development of the molecular electronics. Since more than 40 years, the main objective in this field of research is mainly to store as fast as possible more information in a smaller volume. Nowadays, chemists know how to create molecules with remarkable properties, such as Single–Molecule Magnets (SMMs) and Single–Chain Magnets (SCMs), which show magnetic bistability at low temperature (T < 10 K) providing a memory effect. Therefore, the design of novel materials with original…
Advisors/Committee Members: Fourmigué, Marc (thesis director), Clérac, Rodolphe (thesis director).
Subjects/Keywords: Molécule-aimant; Relaxation lente de l’aimantation; Lien photomagnétique; Conversion de spin; Transfert de charge; Single-molecule magnet; Slow relaxation of magnetization; Photomagnetic linker; Spin-crossover; Charge-transfer
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Record Details
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Gutium Ababei, R. (2011). Synthèses et études de nouveaux matériaux magnétiques et photomagnétiques : What sociology for which democracy? : political rationality and emancipation. (Doctoral Dissertation). Université de Bordeaux I. Retrieved from http://www.theses.fr/2011BOR14238
Chicago Manual of Style (16th Edition):
Gutium Ababei, Rodica. “Synthèses et études de nouveaux matériaux magnétiques et photomagnétiques : What sociology for which democracy? : political rationality and emancipation.” 2011. Doctoral Dissertation, Université de Bordeaux I. Accessed January 16, 2021.
http://www.theses.fr/2011BOR14238.
MLA Handbook (7th Edition):
Gutium Ababei, Rodica. “Synthèses et études de nouveaux matériaux magnétiques et photomagnétiques : What sociology for which democracy? : political rationality and emancipation.” 2011. Web. 16 Jan 2021.
Vancouver:
Gutium Ababei R. Synthèses et études de nouveaux matériaux magnétiques et photomagnétiques : What sociology for which democracy? : political rationality and emancipation. [Internet] [Doctoral dissertation]. Université de Bordeaux I; 2011. [cited 2021 Jan 16].
Available from: http://www.theses.fr/2011BOR14238.
Council of Science Editors:
Gutium Ababei R. Synthèses et études de nouveaux matériaux magnétiques et photomagnétiques : What sociology for which democracy? : political rationality and emancipation. [Doctoral Dissertation]. Université de Bordeaux I; 2011. Available from: http://www.theses.fr/2011BOR14238
30.
Oorschot, J.W.M. van.
Endogenous assessment of myocardial fibrosis with quantitative MRI.
Degree: 2016, University Utrecht
URL: http://dspace.library.uu.nl/handle/1874/328798
;
URN:NBN:NL:UI:10-1874-328798
;
urn:isbn:978-90-393-6510-6
;
URN:NBN:NL:UI:10-1874-328798
;
http://dspace.library.uu.nl/handle/1874/328798
► In this thesis, we have studied the use of quantitative MR contrast mechanisms, that could potentially be used for endogenous detection of myocardial fibrosis in…
(more)
▼ In this thesis, we have studied the use of quantitative MR contrast mechanisms, that could potentially be used for endogenous detection of myocardial fibrosis in the clinic. we have mainly focused on T2*, T1ρ MRI and
Magnetization Transfer Imaging, and found that T1ρ -mapping, and
Magnetization Transfer imaging are most promising. We found a significantly higher T1ρ-relaxation time in myocardial infarct tissue, compared to healthy remote tissue, both in a porcine animal model and chronic infarct patients. A comparison with LGE as gold standard for infarct detection, showed that native T1ρ –maps can be used to locate the myocardial scar area. For diffuse myocardial fibrosis, we have shown that T1ρ relaxation times correlate with the amount of fibrosis, determined by histology, and with extracellular volume fraction, measured in vivo. The results of native T1 –mapping in DCM patients did not indicate a significant relation with extracellular volume fraction in patients. Measurements of
magnetization transfer in an animal model showed a decrease in
magnetization transfer ratio in the infarct area, and the addition of an MT pulse in front of a T1ρ-mapping experiment resulted in a significantly higher T1ρ-relaxation time.
For infarct detection with T1ρ –mapping the main advantage compared to gold standard LGE imaging is that a contrast agent is no longer required. As a first step towards clinical applications, this technique could be used as an alternative in patients that are unable to receive a gadolinium based contrast agent, such as patients with severe renal failure. Also for diffuse fibrosis, T1ρ –mapping can be used as an alternative to the gadolinium based ECV-mapping. When the sensitivity of the technique is significantly increased, it could be considered as an alternative for LGE and ECV-mapping in clinical practice for all patients.
Advisors/Committee Members: Luijten, P.R., Leiner, T., Zwanenburg, J.J.M..
Subjects/Keywords: MRI; Cardiac; Heart; Endogenous; T1rho; Magnetization Transfer; Contrast agent; Native
Record Details
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Oorschot, J. W. M. v. (2016). Endogenous assessment of myocardial fibrosis with quantitative MRI. (Doctoral Dissertation). University Utrecht. Retrieved from http://dspace.library.uu.nl/handle/1874/328798 ; URN:NBN:NL:UI:10-1874-328798 ; urn:isbn:978-90-393-6510-6 ; URN:NBN:NL:UI:10-1874-328798 ; http://dspace.library.uu.nl/handle/1874/328798
Chicago Manual of Style (16th Edition):
Oorschot, J W M van. “Endogenous assessment of myocardial fibrosis with quantitative MRI.” 2016. Doctoral Dissertation, University Utrecht. Accessed January 16, 2021.
http://dspace.library.uu.nl/handle/1874/328798 ; URN:NBN:NL:UI:10-1874-328798 ; urn:isbn:978-90-393-6510-6 ; URN:NBN:NL:UI:10-1874-328798 ; http://dspace.library.uu.nl/handle/1874/328798.
MLA Handbook (7th Edition):
Oorschot, J W M van. “Endogenous assessment of myocardial fibrosis with quantitative MRI.” 2016. Web. 16 Jan 2021.
Vancouver:
Oorschot JWMv. Endogenous assessment of myocardial fibrosis with quantitative MRI. [Internet] [Doctoral dissertation]. University Utrecht; 2016. [cited 2021 Jan 16].
Available from: http://dspace.library.uu.nl/handle/1874/328798 ; URN:NBN:NL:UI:10-1874-328798 ; urn:isbn:978-90-393-6510-6 ; URN:NBN:NL:UI:10-1874-328798 ; http://dspace.library.uu.nl/handle/1874/328798.
Council of Science Editors:
Oorschot JWMv. Endogenous assessment of myocardial fibrosis with quantitative MRI. [Doctoral Dissertation]. University Utrecht; 2016. Available from: http://dspace.library.uu.nl/handle/1874/328798 ; URN:NBN:NL:UI:10-1874-328798 ; urn:isbn:978-90-393-6510-6 ; URN:NBN:NL:UI:10-1874-328798 ; http://dspace.library.uu.nl/handle/1874/328798
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