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1.
Cho, Seongkoo.
Analysis of Impedance Response in Lithium-ion Battery Electrodes.
Degree: 2013, Texas Digital Library
URL: http://hdl.handle.net/1969; 
http://hdl.handle.net/2249.1/66828
► A major amount of degradation in battery life is in the form of chemical degradation due to the formation of Solid Electrolyte Interface (SEI) which…
(more)
▼ A major amount of degradation in battery life is in the form of chemical degradation due to the formation of Solid Electrolyte Interface (SEI) which is a passive film resulting from chemical reaction. Mechanical degradation in the form of fracture formation due to diffusion induced stress can aggravate the aging of the electrode. These mechanisms of deterioration are primary contributors on limiting the durability of Lithium-ion battery (LIB). In addition, an composition of insertion materials such as active material, additive, and binder as well as active particle???s morphological heterogeneity can influence solid-state transport, electronic conductivity and hence, battery performance.
In this study, virtual 3-D microstructures of LIB electrodes with intercalation particles are designed to describe the influence of microstructure on effective electrical conductivity and the electrochemical
impedance. The technique of digital stochastic modeling has been employed for the generation of electrode microstructures consisting of active material, binder, conductive additive and electrolyte. Physicochemical properties for each of the constituent phases have been duly accounted for. Mathematical models have been developed to characterize the electrochemical
impedance of LIB electrode. In this work, we demonstrate the coupling of electrode microstructures to the solid state diffusion
impedance response in LIB electrodes. This model considers not only the effect of heterogeneity in active particle size on the diffusion
impedance response, but also the effect of electrical conductivity, interfacial surface area of the active materials, and volume fraction of the active materials in the porous electrode on the
impedance response. In addition, the impact of the morphology of the active materials on the diffusion
impedance response through utilization of the characteristic diffusion length of active particles and a Sauter mean particle size has been demonstrated.
In order to show the effect of chemical degradation on the
impedance response with focus on aging, the Li-ion diffusion inside an active particle is considered along with SEI. Finally, mechanical degradation induced increase in
impedance is analyzed by coupling diffusion induced fracture with
impedance. These approaches are envisioned to offer a virtual
impedance response probing framework to elucidate the influence of electrode microstructural variability and underlying electrochemical and transport interactions.
Advisors/Committee Members: Mukherjee, Partha P (advisor).
Subjects/Keywords: Electrochemical Impedance
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APA (6th Edition):
Cho, S. (2013). Analysis of Impedance Response in Lithium-ion Battery Electrodes. (Thesis). Texas Digital Library. Retrieved from http://hdl.handle.net/1969; http://hdl.handle.net/2249.1/66828
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Cho, Seongkoo. “Analysis of Impedance Response in Lithium-ion Battery Electrodes.” 2013. Thesis, Texas Digital Library. Accessed March 04, 2021.
http://hdl.handle.net/1969; http://hdl.handle.net/2249.1/66828.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Cho, Seongkoo. “Analysis of Impedance Response in Lithium-ion Battery Electrodes.” 2013. Web. 04 Mar 2021.
Vancouver:
Cho S. Analysis of Impedance Response in Lithium-ion Battery Electrodes. [Internet] [Thesis]. Texas Digital Library; 2013. [cited 2021 Mar 04].
Available from: http://hdl.handle.net/1969; http://hdl.handle.net/2249.1/66828.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Cho S. Analysis of Impedance Response in Lithium-ion Battery Electrodes. [Thesis]. Texas Digital Library; 2013. Available from: http://hdl.handle.net/1969; http://hdl.handle.net/2249.1/66828
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Texas A&M University
2.
Sobahi, Nebras MohammedKamal A.
Development of High-Throughput Microfluidic Impedance Spectroscopy Platform for Analyzing Microdroplets in Droplet Microfluidic System.
Degree: MS, Electrical Engineering, 2014, Texas A&M University
URL: http://hdl.handle.net/1969.1/153517
► This thesis presents the development of a high-throughput microfluidic impedance spectroscopy platform for electrically detecting analyzing impedance measurements of non-contact and label free microdroplets. This…
(more)
▼ This thesis presents the development of a high-throughput microfluidic
impedance spectroscopy platform for electrically detecting analyzing
impedance measurements of non-contact and label free microdroplets. This microfluidic
impedance spectroscopy platform gives valuable information of the size and contents of the microdroplets in general and particularly of cells encapsulated within droplets.
Impedance spectroscopy is a common method for analyzing dielectric properties of particles with respect to the stimulating frequency. Microfluidic based
impedance spectroscopy can analyze up to micro size particles. However, droplets based microfluidic
impedance spectroscopy systems for analyzing cells encapsulated within droplets have been rarely developed.
However, to develop a high-throughput system, a novel sensitive high-throughput droplets based microfluidic
impedance spectroscopy platform for analyzing cells encapsulated with droplets at different levels concentrations at throughput of 140 Hz which has not been reported in the literature yet.
The device sensitivity was demonstrated using chlamydomonas reinhardtii cells. Two throughputs (17 and 140 droplets/s) for four level of cells concentrations were discriminating and compared. The maximum deviation in the acquired data for both cases was 6.9%. At 10% difference of cells encapsulated within droplets, the device was capable of discriminating and distinguishing different between the encapsulated microdroplets.
Advisors/Committee Members: Han, Arum (advisor), Ji, Jim X (committee member), Palermo, Samuel (committee member), Yakovlev, Vladislav V (committee member).
Subjects/Keywords: microfluidic; impedance
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APA (6th Edition):
Sobahi, N. M. A. (2014). Development of High-Throughput Microfluidic Impedance Spectroscopy Platform for Analyzing Microdroplets in Droplet Microfluidic System. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/153517
Chicago Manual of Style (16th Edition):
Sobahi, Nebras MohammedKamal A. “Development of High-Throughput Microfluidic Impedance Spectroscopy Platform for Analyzing Microdroplets in Droplet Microfluidic System.” 2014. Masters Thesis, Texas A&M University. Accessed March 04, 2021.
http://hdl.handle.net/1969.1/153517.
MLA Handbook (7th Edition):
Sobahi, Nebras MohammedKamal A. “Development of High-Throughput Microfluidic Impedance Spectroscopy Platform for Analyzing Microdroplets in Droplet Microfluidic System.” 2014. Web. 04 Mar 2021.
Vancouver:
Sobahi NMA. Development of High-Throughput Microfluidic Impedance Spectroscopy Platform for Analyzing Microdroplets in Droplet Microfluidic System. [Internet] [Masters thesis]. Texas A&M University; 2014. [cited 2021 Mar 04].
Available from: http://hdl.handle.net/1969.1/153517.
Council of Science Editors:
Sobahi NMA. Development of High-Throughput Microfluidic Impedance Spectroscopy Platform for Analyzing Microdroplets in Droplet Microfluidic System. [Masters Thesis]. Texas A&M University; 2014. Available from: http://hdl.handle.net/1969.1/153517
Indian Institute of Science
3.
Naik, Dinesh.
Development of Handheld Impedance Spectroscopy Instrument Suitable for Biological Tissue Characterization.
Degree: MSc Engg, Faculty of Engineering, 2017, Indian Institute of Science
URL: http://etd.iisc.ac.in/handle/2005/2813
► Impedance spectroscopy (IS) is a powerful and sophisticated tool to characterize intrinsic electrical properties of any materials and its interface, measuring the electric and transport…
(more)
▼ Impedance spectroscopy (IS) is a powerful and sophisticated tool to characterize intrinsic electrical properties of any materials and its interface, measuring the electric and transport properties of the materials, investigating the mechanism of electrochemical reaction etc. The fundamental principle of IS is the measurement of the
impedance (equivalent to resistance in DC analysis) of the system under investigation over a wide frequency range. The IS study provides quantitative information about the conductance, the dielectric coefficient, the static properties of the interfaces like contact resistance, and its dynamic change due to adsorption or charge transfer phenomenon. Commercial
Impedance analyzers that are available today are bulky and cannot be carried or deployed at remote locations for monitoring so easily, also such systems are expensive.
Though IS concept is not new, standard
Impedance analyzers are interfaced to the computer and require detailed analysis of the data by experts. Advancement in data conversion and signal processing is opening up opportunities for handheld smart devices. Hence it is felt that there is a need to develop a versatile low cost, portable (handheld)
impedance analyzer instrument which can be used to characterize non linear materials like semiconductors, biological objects, and electrochemical samples. The instrument should be capable accepting test parameters using a touch screen based keypad and display test results on a Graphical LCD for quick analysis. Hence a standalone handheld instrument is designed to work independently without any PC control.
The designed instrument consists of Digital Direct Synthesis (DDS) signal generator, a constant current source, Analog to digital convertor, Microcontroller to control frequency sweep parameters and acquire data, TFT Graphics LCD for displaying various plots, touch screen user interface to input sweep parameters and data storage section for offline analysis of obtained data. The instrument is designed to work on a battery or a regulated power supply. The instrument has options to display Nyquist plot, capacitance versus frequency plot, real and imaginary value of
impedance versus frequency plot etc.
Experimental investigations are conducted using this instrument on few passive components like resistor, inductor, capacitor and combinations. The instrument is also used to monitor the performance of polyimide based capacitive humidity sensor and its characteristics like sensitivity, linearity, repeatability and hysteresis. The measurement accuracy of the
impedance varies from 0.7% to 4.67% depending on the
impedance range.
Bio
impedance measurements are carried out on biological samples like Banana and the measured values are compared with the standard LCR meter. The bio
impedance measurements are repeatable and comparable with the standard LCR meter readings and it is found to be within ±1% accuracy at the calibrated frequency.
The instrument is also validated using industry standard Gauge R & R procedure to understand the…
Advisors/Committee Members: Nagaraju, J (advisor).
Subjects/Keywords: Bio Impedance Spectroscopy; Tissue Impedance; Impedance Spectroscopy; Handheld Impedance Analyzer; Bio Impedance Measurement (BIS); Instrumentation
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APA (6th Edition):
Naik, D. (2017). Development of Handheld Impedance Spectroscopy Instrument Suitable for Biological Tissue Characterization. (Masters Thesis). Indian Institute of Science. Retrieved from http://etd.iisc.ac.in/handle/2005/2813
Chicago Manual of Style (16th Edition):
Naik, Dinesh. “Development of Handheld Impedance Spectroscopy Instrument Suitable for Biological Tissue Characterization.” 2017. Masters Thesis, Indian Institute of Science. Accessed March 04, 2021.
http://etd.iisc.ac.in/handle/2005/2813.
MLA Handbook (7th Edition):
Naik, Dinesh. “Development of Handheld Impedance Spectroscopy Instrument Suitable for Biological Tissue Characterization.” 2017. Web. 04 Mar 2021.
Vancouver:
Naik D. Development of Handheld Impedance Spectroscopy Instrument Suitable for Biological Tissue Characterization. [Internet] [Masters thesis]. Indian Institute of Science; 2017. [cited 2021 Mar 04].
Available from: http://etd.iisc.ac.in/handle/2005/2813.
Council of Science Editors:
Naik D. Development of Handheld Impedance Spectroscopy Instrument Suitable for Biological Tissue Characterization. [Masters Thesis]. Indian Institute of Science; 2017. Available from: http://etd.iisc.ac.in/handle/2005/2813
4.
Magnusson, Karolina.
Mechanical heart rate detection using cardiogenic impedance - a morphology approach.
Degree: Faculty of Science & Engineering, 2015, Linköping UniversityLinköping University
URL: http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-119381
► The objective of this thesis is to examine the possibility to determine the mechanical heart rate using intracardiac impedance in the time domain. Deducing…
(more)
▼ The objective of this thesis is to examine the possibility to determine the mechanical heart rate using intracardiac impedance in the time domain. Deducing the mechanical heartrate from the impedance could help improve the performance of implanted devices that today depend on the measurement of the heart’s electrical activity. Cardiogenic – also known as intracardiac – impedance is based on the difference in conductivity between heart muscle tissue and blood, making the impedance vary as the heart is filled and emptied. The data used in this thesis was acquired from three previous studies performed by St Jude Medical, two clinical and one preclinical. Two impedance measurement configurations were chosen from these studies, one bipolar and one quadropolar. To deduce the heart rate from the intracardiac impedance six algorithms were evaluated. Three using continuous peak detection and three evaluating small frames of the impedance signal.The peak detection algorithms were peak detection on the impedance signal itself, on its derivative and on its integral. The three others were an Auto Correlation Function (ACF), an Average Magnutide Difference Function (AMDF) and an Average Wave Comparison Function (AWCF). In order to assess the heart rates deduced from the intracardiac impedance by the algorithms, these rates were compared to both the IEGM or the ECG (depending on which study was at hand) and the blood pressure. Several issues affected the performance of the algorithms. Impedance morphology can vary between patients. Some display so called “double peaks”, making it hard to decide whether a patient has for example a pulse of 80 bpm or of 160 bpm. The impedance morphology was also affected by amplitude modulation with the respiration frequency which in some patients cause difficulties to analyze the impedance signal. The results show that the two impedance measurement configurations perform equally well and that the ACF method was the overall best performing algorithm. They also show that individual patient impedance morphology has a large influence on the results and for future studies it should therefore be interesting to calibrate the algorithms for each patient, as this should improve performance.
Subjects/Keywords: Cardiogenic impedance; heart beat detection; intracardiac impedance
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APA (6th Edition):
Magnusson, K. (2015). Mechanical heart rate detection using cardiogenic impedance - a morphology approach. (Thesis). Linköping UniversityLinköping University. Retrieved from http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-119381
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Magnusson, Karolina. “Mechanical heart rate detection using cardiogenic impedance - a morphology approach.” 2015. Thesis, Linköping UniversityLinköping University. Accessed March 04, 2021.
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-119381.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Magnusson, Karolina. “Mechanical heart rate detection using cardiogenic impedance - a morphology approach.” 2015. Web. 04 Mar 2021.
Vancouver:
Magnusson K. Mechanical heart rate detection using cardiogenic impedance - a morphology approach. [Internet] [Thesis]. Linköping UniversityLinköping University; 2015. [cited 2021 Mar 04].
Available from: http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-119381.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Magnusson K. Mechanical heart rate detection using cardiogenic impedance - a morphology approach. [Thesis]. Linköping UniversityLinköping University; 2015. Available from: http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-119381
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Colorado State University
5.
Kern, Tucker.
Design of integrated on-chip impedance sensors.
Degree: MS(M.S.), Electrical and Computer Engineering, 2014, Colorado State University
URL: http://hdl.handle.net/10217/83982
► In this thesis two integrated sensor systems for measuring the impedance of a device under test (DUT) are presented. Both sensors have potential applications in…
(more)
▼ In this thesis two integrated sensor systems for measuring the
impedance of a device under test (DUT) are presented. Both sensors have potential applications in label-free affinity biosensors for biological and bio-medical analysis. The first sensor is a purely capacitive sensor that operates on the theory of capacitive division. Test capacitance is placed within a capacitive divider and produces an output voltage proportional to its value. This voltage is then converted to a timedomain signal for easy readout. The prototype capacitive sensor shows a resolution of 5 fF on a base of 500 fF, which corresponds to a 1 % resolution. The second sensor, a general purpose
impedance sensor calculates the ratio between a DUT and reference
impedance when stimulated by a sinusoidal signal. Computation of DUT magnitude and phase is accomplished in silicon via mixed-signal division and a phase module. An automatic gain controller (AGC) allows the sensor to measure
impedance from 30 Ω to 2.5 MΩ with no more than 10 % error and a resolution of at least .44 %. Prototypes of both sensing topologies were implemented in a .18 μm CMOS process and their operation in silicon was verified. The prototype capacitive sensor required a circuit area of .014 mm2 and successfully demonstrated a resolution of 5 fF in silicon. A prototype
impedance sensor without the phase module or AGC was implemented with a circuit area of .17 mm2. Functional verification of the peak capture systems and mixed-signal divider was accomplished. The complete implementation of the
impedance sensor, with phase module and AGC, requires an estimated .28 mm2 of circuit area.
Advisors/Committee Members: Chen, Thomas W. (advisor), Pezeshki, Ali (committee member), Tobet, Stuart (committee member).
Subjects/Keywords: CMOS; sensor; impedance
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APA (6th Edition):
Kern, T. (2014). Design of integrated on-chip impedance sensors. (Masters Thesis). Colorado State University. Retrieved from http://hdl.handle.net/10217/83982
Chicago Manual of Style (16th Edition):
Kern, Tucker. “Design of integrated on-chip impedance sensors.” 2014. Masters Thesis, Colorado State University. Accessed March 04, 2021.
http://hdl.handle.net/10217/83982.
MLA Handbook (7th Edition):
Kern, Tucker. “Design of integrated on-chip impedance sensors.” 2014. Web. 04 Mar 2021.
Vancouver:
Kern T. Design of integrated on-chip impedance sensors. [Internet] [Masters thesis]. Colorado State University; 2014. [cited 2021 Mar 04].
Available from: http://hdl.handle.net/10217/83982.
Council of Science Editors:
Kern T. Design of integrated on-chip impedance sensors. [Masters Thesis]. Colorado State University; 2014. Available from: http://hdl.handle.net/10217/83982
University of Florida
6.
Alexander, Christopher L.
Impedance Spectroscopy The Influence of Surface Heterogeneity and Application to Corrosion Monitoring of Bridge Tendons.
Degree: PhD, Chemical Engineering, 2017, University of Florida
URL: https://ufdc.ufl.edu/UFE0051021
► External post-tensioned tendons are used in bridge construction to link precast concrete segments together. The tendons consist of 7-wire high-strength steel strands contained within a…
(more)
▼ External post-tensioned tendons are used in bridge construction to link precast concrete segments together. The tendons consist of 7-wire high-strength steel strands contained within a HDPE duct, which is filled with an alkaline grout to protect against corrosion. Despite the use of grout, corrosion has occurred in as little as 7 years compromising the integrity and safety of the bridge. Non-destructive techniques are needed to determine the integrity of the steel without having to break open the tendon. An indirect
impedance technique is proposed as a way to detect corrosion within the tendons before failure of the steel occurs. By inserting 4 electrodes into the duct of the tendon to establish electric contact to the grout, the
impedance of the grout and the grout and steel interface may be measured. Bench-top experiments were performed on fabricated tendons with and without induced corrosion to show that the indirect
impedance was sensitive to the properties of the steel and grout interface. The biggest obstacle in the application of this technique is the lack of a reliable way of interpreting the data. Due to the geometry of the tendon and the configuration of the indirect
impedance, frequency dispersion occurs at low frequencies which obscures the actual
impedance of the steel. Finite-element models were used to simulate the indirect
impedance and determine how the
impedance of the grout contributed to the indirect
impedance.
Advisors/Committee Members: ORAZEM,MARK E (committee chair), ZIEGLER,KIRK JEREMY (committee member), BLOOMQUIST,DAVID G (committee member), VIVIER,VINCENT (committee member).
Subjects/Keywords: corrosion – electrochemistry – impedance
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APA (6th Edition):
Alexander, C. L. (2017). Impedance Spectroscopy The Influence of Surface Heterogeneity and Application to Corrosion Monitoring of Bridge Tendons. (Doctoral Dissertation). University of Florida. Retrieved from https://ufdc.ufl.edu/UFE0051021
Chicago Manual of Style (16th Edition):
Alexander, Christopher L. “Impedance Spectroscopy The Influence of Surface Heterogeneity and Application to Corrosion Monitoring of Bridge Tendons.” 2017. Doctoral Dissertation, University of Florida. Accessed March 04, 2021.
https://ufdc.ufl.edu/UFE0051021.
MLA Handbook (7th Edition):
Alexander, Christopher L. “Impedance Spectroscopy The Influence of Surface Heterogeneity and Application to Corrosion Monitoring of Bridge Tendons.” 2017. Web. 04 Mar 2021.
Vancouver:
Alexander CL. Impedance Spectroscopy The Influence of Surface Heterogeneity and Application to Corrosion Monitoring of Bridge Tendons. [Internet] [Doctoral dissertation]. University of Florida; 2017. [cited 2021 Mar 04].
Available from: https://ufdc.ufl.edu/UFE0051021.
Council of Science Editors:
Alexander CL. Impedance Spectroscopy The Influence of Surface Heterogeneity and Application to Corrosion Monitoring of Bridge Tendons. [Doctoral Dissertation]. University of Florida; 2017. Available from: https://ufdc.ufl.edu/UFE0051021
University of Florida
7.
Zou, Liuruidong.
Application of Lissajous Plots to Identify Non-Stationary Behavior in Impedance Spectroscopy.
Degree: MS, Chemical Engineering, 2020, University of Florida
URL: https://ufdc.ufl.edu/UFE0056551
► When examining properties of unknown devices spectrum of impedance are critical for overlooking the electrochemical properties of devices. Electrochemical impedance spectroscopy(EIS) measuring the transfer function…
(more)
▼ When examining properties of unknown devices spectrum of
impedance are critical for overlooking the electrochemical properties of devices. Electrochemical
impedance spectroscopy(EIS) measuring the transfer function which connecting the input potential and output current. Identification of non-stationary behavior in EIS requires post-processing by application of measurement model simulation based on Kramers-Kronig relations.The objective of this thesis was to explore the suitability of instantaneously measured Lissajous figures for identifying non-stationary behavior. Despite transmitting
impedance spectrum a script written by Prof. Buruk Ulgut was used to obtain averaged and instantaneous Lissajous plots for the
impedance measurements of steel electrode, titanium alloy electrode and red quantum-dot light emitting diodes provided by Nanophotonica. Comparison between the two Lissajous plots printing methods revealed that instantaneous Lissajous plots were shown to be sensitive to nonstationary behavior, even when the averaged Lissajous plot suggested stationary behavior. Instantaneous Lissajous plots were shown to provide a simple manner by which non-stationary behavior could be detected during the course of an
impedance measurement. Comparison to use of a measurement model to assess consistency with the Kramers-Kronig relations to measured spectra showed that the instantaneous Lissajous plots could detect non-stationary behavior under conditions for which the measurement model gave inconclusive results. ( en )
Advisors/Committee Members: Orazem,Mark E (committee chair).
Subjects/Keywords: impedance – lissajous – nonstationary
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APA (6th Edition):
Zou, L. (2020). Application of Lissajous Plots to Identify Non-Stationary Behavior in Impedance Spectroscopy. (Masters Thesis). University of Florida. Retrieved from https://ufdc.ufl.edu/UFE0056551
Chicago Manual of Style (16th Edition):
Zou, Liuruidong. “Application of Lissajous Plots to Identify Non-Stationary Behavior in Impedance Spectroscopy.” 2020. Masters Thesis, University of Florida. Accessed March 04, 2021.
https://ufdc.ufl.edu/UFE0056551.
MLA Handbook (7th Edition):
Zou, Liuruidong. “Application of Lissajous Plots to Identify Non-Stationary Behavior in Impedance Spectroscopy.” 2020. Web. 04 Mar 2021.
Vancouver:
Zou L. Application of Lissajous Plots to Identify Non-Stationary Behavior in Impedance Spectroscopy. [Internet] [Masters thesis]. University of Florida; 2020. [cited 2021 Mar 04].
Available from: https://ufdc.ufl.edu/UFE0056551.
Council of Science Editors:
Zou L. Application of Lissajous Plots to Identify Non-Stationary Behavior in Impedance Spectroscopy. [Masters Thesis]. University of Florida; 2020. Available from: https://ufdc.ufl.edu/UFE0056551
Queens University
8.
Swyer, Ian.
Considerations on the use of Impedance Spectroscopy for the Detection of Virions Trapped in Quadrupolar Microelectrode Arrays
.
Degree: Chemical Engineering, 2011, Queens University
URL: http://hdl.handle.net/1974/6528
► The impedance response of a quadrupolar microelectrode array was studied over a wide frequency range to determine whether particles captured at the center of the…
(more)
▼ The impedance response of a quadrupolar microelectrode array was studied over a wide frequency range to determine whether particles captured at the center of the array could be detected impedimetrically. The microelectrode array (denoted as DEP chip) uses dielectrophoretic forces to concentrate particles at its center. Initial results showed that there was a large electrode-silicon-electrode (ESE) capacitance which dominated at high frequencies. This capacitance was reduced by decreasing the electrode area and increasing the insulating layer thickness. These measures however proved fruitless as this capacitance was still significantly greater then the dielectric capacitance of the chip. This ESE capacitance can be eliminated through the use of a glass substrate so that the dielectric response of the chip dominates at higher frequencies. Since the ESE capacitance prevented experimental validation of impedance spectroscopy as a signal transduction method, computer simulations were performed. These simulations indicated that capture with the current DEP chips would not have a significant impact on the impedance of the chip. Decreasing the electrode gap distance and reducing the area of the electrodes, which is recommended for future work, can remedy this.
As measureable changes in the dielectric capacitance of the chip are not possible, a reaction scheme was developed to translate the capture of viral particles into a change in medium conductivity. An ELISA type system was proposed where the viral particles would be functionalized with urease. This uease would then be used to degrade non-ionic urea into ionic products thereby increasing the medium conductivity. A model was formulated to predict the conductivity increase expected for low concentrations, and validated using higher concentrations of biotinylated-urease. Urease from commercial sources proved not to be a viable option as it does not possess a high enough activity to produce a significant conductivity change given the low concentrations of viral particles expected after collection. Urease with suitable activity is produced by the organism Ureaplasma urealyticum which has an activity of 180 000 µmol urea catalyzed min-1 mg urease-1. It is not recommended that this method be pursued further due to technical challenges that would be encountered.
Subjects/Keywords: Impedance
;
Biosensors
;
Microfluidic
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APA (6th Edition):
Swyer, I. (2011). Considerations on the use of Impedance Spectroscopy for the Detection of Virions Trapped in Quadrupolar Microelectrode Arrays
. (Thesis). Queens University. Retrieved from http://hdl.handle.net/1974/6528
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Swyer, Ian. “Considerations on the use of Impedance Spectroscopy for the Detection of Virions Trapped in Quadrupolar Microelectrode Arrays
.” 2011. Thesis, Queens University. Accessed March 04, 2021.
http://hdl.handle.net/1974/6528.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Swyer, Ian. “Considerations on the use of Impedance Spectroscopy for the Detection of Virions Trapped in Quadrupolar Microelectrode Arrays
.” 2011. Web. 04 Mar 2021.
Vancouver:
Swyer I. Considerations on the use of Impedance Spectroscopy for the Detection of Virions Trapped in Quadrupolar Microelectrode Arrays
. [Internet] [Thesis]. Queens University; 2011. [cited 2021 Mar 04].
Available from: http://hdl.handle.net/1974/6528.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Swyer I. Considerations on the use of Impedance Spectroscopy for the Detection of Virions Trapped in Quadrupolar Microelectrode Arrays
. [Thesis]. Queens University; 2011. Available from: http://hdl.handle.net/1974/6528
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Brno University of Technology
9.
Sliž, Jiří.
Impedanční spektroskop: Impedance Spectroscope.
Degree: 2019, Brno University of Technology
URL: http://hdl.handle.net/11012/27562
► The aim of this thesis is to design a measuring instrument intended for impedance spectroscopy. There are definitions of the terms impedance and impedance spectroscopy…
(more)
▼ The aim of this thesis is to design a measuring instrument intended for
impedance spectroscopy. There are definitions of the terms
impedance and
impedance spectroscopy and methods of its measurement. The integrated circuit AD5933 from Analog Devices was used for measurement. The measuring device is controlled by a microcontroller PIC32MX460F512L, which communicates with the measuring circuit, controls the actual measurement and communication with the control PC via the USB interface. The work also includes the creation of the control program, which ensures calibration, measurement, storage data, and data visualization. Device has also the possibility of repeated measurements and automatic switching of multiple inputs. Finally, the proposed device has been tested on two microbiological experiments.
Impedance change depending on the concentration of bacteria in the measured solution was proved in first experiment. The aim of the second experiment is to distinguish bacterial strains of Staphylococcus epidermidis which creates biofilm and which not. With PLS was created validation model that can be used as a detector strains forming biofilm.
Advisors/Committee Members: Beneš, Petr (advisor), Pikula, Stanislav (referee).
Subjects/Keywords: Impedance; Impedanční spektroskopie; Frekvenční charakteristika; Impedance; Impedance spectroscopy; Bode plot
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APA (6th Edition):
Sliž, J. (2019). Impedanční spektroskop: Impedance Spectroscope. (Thesis). Brno University of Technology. Retrieved from http://hdl.handle.net/11012/27562
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Sliž, Jiří. “Impedanční spektroskop: Impedance Spectroscope.” 2019. Thesis, Brno University of Technology. Accessed March 04, 2021.
http://hdl.handle.net/11012/27562.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Sliž, Jiří. “Impedanční spektroskop: Impedance Spectroscope.” 2019. Web. 04 Mar 2021.
Vancouver:
Sliž J. Impedanční spektroskop: Impedance Spectroscope. [Internet] [Thesis]. Brno University of Technology; 2019. [cited 2021 Mar 04].
Available from: http://hdl.handle.net/11012/27562.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Sliž J. Impedanční spektroskop: Impedance Spectroscope. [Thesis]. Brno University of Technology; 2019. Available from: http://hdl.handle.net/11012/27562
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Brno University of Technology
10.
Přibyl, Jakub.
Studium interakce DNA a doxorubicinu elektrochemickými metodami na nanostrukturovaných elektrodách: Study of DNA-doxorubicine interaction by electrochemical methods on nanostructured electrodes.
Degree: 2018, Brno University of Technology
URL: http://hdl.handle.net/11012/26176
► Cancer diseases are one of the leading causes of mortality worldwide, for this reason, great attention anticancer drugs. Doxorubicin falls into the category of the…
(more)
▼ Cancer diseases are one of the leading causes of mortality worldwide, for this reason, great attention anticancer drugs. Doxorubicin falls into the category of the most widely used cancer drugs. The method of electrochemical
impedance spectroscopy were investigated properties of golds electrodes without deposit nanoparticles and electrodes with deposit gold nanoparticles. Using voltammetric measurements we detected doxorubicin and investigated the interaction of doxorubicin with oligonucleotides on gold electrodes without nanoparticles and electrodes modified with gold nanoparticles.
Advisors/Committee Members: Kynclová, Hana (advisor), Fohlerová, Zdenka (referee).
Subjects/Keywords: Deoxyribonukleová kyselina; Doxorubicin; Impedance; Impedanční spektroskopie; Voltametrie; Deoxyribonucleic acid; Doxorubicin; Impedance; Impedance Spectroscopy; Voltammetry
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APA ·
Chicago ·
MLA ·
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CSE |
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to Zotero / EndNote / Reference
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APA (6th Edition):
Přibyl, J. (2018). Studium interakce DNA a doxorubicinu elektrochemickými metodami na nanostrukturovaných elektrodách: Study of DNA-doxorubicine interaction by electrochemical methods on nanostructured electrodes. (Thesis). Brno University of Technology. Retrieved from http://hdl.handle.net/11012/26176
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Přibyl, Jakub. “Studium interakce DNA a doxorubicinu elektrochemickými metodami na nanostrukturovaných elektrodách: Study of DNA-doxorubicine interaction by electrochemical methods on nanostructured electrodes.” 2018. Thesis, Brno University of Technology. Accessed March 04, 2021.
http://hdl.handle.net/11012/26176.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Přibyl, Jakub. “Studium interakce DNA a doxorubicinu elektrochemickými metodami na nanostrukturovaných elektrodách: Study of DNA-doxorubicine interaction by electrochemical methods on nanostructured electrodes.” 2018. Web. 04 Mar 2021.
Vancouver:
Přibyl J. Studium interakce DNA a doxorubicinu elektrochemickými metodami na nanostrukturovaných elektrodách: Study of DNA-doxorubicine interaction by electrochemical methods on nanostructured electrodes. [Internet] [Thesis]. Brno University of Technology; 2018. [cited 2021 Mar 04].
Available from: http://hdl.handle.net/11012/26176.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Přibyl J. Studium interakce DNA a doxorubicinu elektrochemickými metodami na nanostrukturovaných elektrodách: Study of DNA-doxorubicine interaction by electrochemical methods on nanostructured electrodes. [Thesis]. Brno University of Technology; 2018. Available from: http://hdl.handle.net/11012/26176
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
University of Kentucky
11.
Liu, Jinghao.
ADVANCED STUDIES ON SERIES IMPEDANCE IN WAVEGUIDES WITH AN EMPHASIS ON SOURCE AND TRANSFER IMPEDANCE.
Degree: 2011, University of Kentucky
URL: https://uknowledge.uky.edu/gradschool_diss/821
► Series impedances, including source and transfer impedances, are commonly used to model a variety of noise sources and noise treatment elements in duct systems. Particle…
(more)
▼ Series impedances, including source and transfer impedances, are commonly used to model a variety of noise sources and noise treatment elements in duct systems. Particle velocity is assumed to be constant on the plane where the series impedances are defined. The research reported herein details investigations into measuring source and transfer impedance. Especially, the measurement and prediction of the transfer impedance of micro-perforated panel (MPP) absorbers is considered.
A wave decomposition method for measuring source impedance and source strength was developed that was purely based on acoustic concepts instead of the equivalent circuit analysis. The method developed is a two-load method. However, it is not necessary to know the impedances of either load a priori. The selection of proper loads was investigated via an error analysis, and the results suggested that it was best to choose one resistive and one reactive load.
In addition, a novel type of perforated element was investigated. MPP absorbers are metal or plastic panels with sub-millimeter size holes or slits. In the past, Maa's equation has been used to characterize their performance. However, Maa's equation is only valid for circular perforations. In this research, an inverse method using a nonlinear least square data fitting algorithm was developed to estimate effective parameters that could be used in Maa's theory.
This inverse approach was also used to aid in understanding the effect of dust and fluid contamination on the performance of MPP absorbers. In addition, an approach to enhance the attenuation of MPP absorbers by partitioning the backing cavity was investigated experimentally and numerically. Results indicated that partitioning improved the attenuating of grazing sound waves.
The effect of modifying both the source and transfer impedances on the system response was also studied using the Moebius transformation. It was demonstrated that the Moebius transformation is a mathematical tool that can be employed to aid in determining and understanding the impact of acoustic impedance modifications on a vibro-acoustic system.
Subjects/Keywords: series impedance; source impedance; transfer impedance; microperforated panel absorbers; Moebius transformation; Mechanical Engineering
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APA ·
Chicago ·
MLA ·
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CSE |
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to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Liu, J. (2011). ADVANCED STUDIES ON SERIES IMPEDANCE IN WAVEGUIDES WITH AN EMPHASIS ON SOURCE AND TRANSFER IMPEDANCE. (Doctoral Dissertation). University of Kentucky. Retrieved from https://uknowledge.uky.edu/gradschool_diss/821
Chicago Manual of Style (16th Edition):
Liu, Jinghao. “ADVANCED STUDIES ON SERIES IMPEDANCE IN WAVEGUIDES WITH AN EMPHASIS ON SOURCE AND TRANSFER IMPEDANCE.” 2011. Doctoral Dissertation, University of Kentucky. Accessed March 04, 2021.
https://uknowledge.uky.edu/gradschool_diss/821.
MLA Handbook (7th Edition):
Liu, Jinghao. “ADVANCED STUDIES ON SERIES IMPEDANCE IN WAVEGUIDES WITH AN EMPHASIS ON SOURCE AND TRANSFER IMPEDANCE.” 2011. Web. 04 Mar 2021.
Vancouver:
Liu J. ADVANCED STUDIES ON SERIES IMPEDANCE IN WAVEGUIDES WITH AN EMPHASIS ON SOURCE AND TRANSFER IMPEDANCE. [Internet] [Doctoral dissertation]. University of Kentucky; 2011. [cited 2021 Mar 04].
Available from: https://uknowledge.uky.edu/gradschool_diss/821.
Council of Science Editors:
Liu J. ADVANCED STUDIES ON SERIES IMPEDANCE IN WAVEGUIDES WITH AN EMPHASIS ON SOURCE AND TRANSFER IMPEDANCE. [Doctoral Dissertation]. University of Kentucky; 2011. Available from: https://uknowledge.uky.edu/gradschool_diss/821
University of Utah
12.
Roberts, Deanne Davis.
Electrical impedance of human urine;.
Degree: MS;, Nursing;, 1980, University of Utah
URL: http://content.lib.utah.edu/cdm/singleitem/collection/etd1/id/348/rec/442
► Electrical impedance measurements were taken on 269 samples of human urine to compare the mean impedance of abnormal urine to the mean impedance of normal…
(more)
▼ Electrical impedance measurements were taken on 269 samples of human urine to compare the mean impedance of abnormal urine to the mean impedance of normal urine. Samples obtained from the population of specimens sent to The University of Utah Clinical Chemistry Lab were assigned to seven different categories based on their urinalysis results. The methodology controlled for the following variables: (1) solution volume; (2) type, size and distance between electrodes; (3) frequency and amperage of the input current; and, (4) temperature of the solution. Impedance measurements were taken using a High Resolution Impedance Convertor (Transmed Scientific Model 2991), which provided 50 uA constant current at 50 kHz. The results of this study indicate that: (1) There is no significant difference in mean impedance between normal urine and urine containing higher than normal amounts of either red blood cells, white blood cells, protein, glucose, bacteria, or Pyridium; and, (2) there is a significant difference between the mean impedance of normal urine and urine that is either concentrated (specific gravity ? 1.025) or dilute (specific gravity ? 1.003). It was also found that impedance readings varied considerably within each category. These findings suggest that factors other than those identified for this study may significantly influence the electrical impedance of human urine.
Subjects/Keywords: Impedance; Bioelectric
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CSE |
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Manager
APA (6th Edition):
Roberts, D. D. (1980). Electrical impedance of human urine;. (Masters Thesis). University of Utah. Retrieved from http://content.lib.utah.edu/cdm/singleitem/collection/etd1/id/348/rec/442
Chicago Manual of Style (16th Edition):
Roberts, Deanne Davis. “Electrical impedance of human urine;.” 1980. Masters Thesis, University of Utah. Accessed March 04, 2021.
http://content.lib.utah.edu/cdm/singleitem/collection/etd1/id/348/rec/442.
MLA Handbook (7th Edition):
Roberts, Deanne Davis. “Electrical impedance of human urine;.” 1980. Web. 04 Mar 2021.
Vancouver:
Roberts DD. Electrical impedance of human urine;. [Internet] [Masters thesis]. University of Utah; 1980. [cited 2021 Mar 04].
Available from: http://content.lib.utah.edu/cdm/singleitem/collection/etd1/id/348/rec/442.
Council of Science Editors:
Roberts DD. Electrical impedance of human urine;. [Masters Thesis]. University of Utah; 1980. Available from: http://content.lib.utah.edu/cdm/singleitem/collection/etd1/id/348/rec/442
San Jose State University
13.
Rayfield, Kurtis Ryan.
Effects of Optimizing the Respiratory Pump on Performance During a Simulated Ice Hockey Period.
Degree: MA, Kinesiology, 2018, San Jose State University
URL: https://doi.org/10.31979/etd.9pf7-9u25
;
https://scholarworks.sjsu.edu/etd_theses/4978
► The inspiratory impedance threshold device (ITD) was designed to increase negative intrathoracic pressure and, thus, improve the body’s natural ability to deliver and return…
(more)
▼ The inspiratory impedance threshold device (ITD) was designed to increase negative intrathoracic pressure and, thus, improve the body’s natural ability to deliver and return blood to the heart. Five ice hockey athletes participated in this study because of the high physiological demands associated with the sport, the more predictable nature of their shifts, and the inactive rest between shifts. The participants skated a course, the Peterson On-Ice Repeated Sprint Test, eight times (shifts) with 90 s recovery between each shift. During the recovery periods, participants breathed with or without the ITD. The test conditions were randomized and counterbalanced with 48 hr between test conditions. Performance, measured as time to skate the course, was comparable between conditions (p = .21); however, lactate measured after the 8th shift was lower, although not statistically significant, during the ITD condition compared to the control (10.9 ± 1.5 mM and 14.0 ± 0.4 mM, respectively, t(4) = -2.591, p = .06). Athletes rated their exertion lower when using the ITD during recovery (F(8, 32) = 4.199, p < 0.01). Thus, use of the ITD positively affected lactate and perceived exertion when performing repeated ice hockey shifts using the Peterson Repeated Sprint Test. Future research using the ITD technology may help to better characterize its effects on performance as well as the physiological and perceptual responses associated with its use during repeated bouts of high-intensity exercise.
Subjects/Keywords: inspiratory impedance threshold device
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MLA ·
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Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Rayfield, K. R. (2018). Effects of Optimizing the Respiratory Pump on Performance During a Simulated Ice Hockey Period. (Masters Thesis). San Jose State University. Retrieved from https://doi.org/10.31979/etd.9pf7-9u25 ; https://scholarworks.sjsu.edu/etd_theses/4978
Chicago Manual of Style (16th Edition):
Rayfield, Kurtis Ryan. “Effects of Optimizing the Respiratory Pump on Performance During a Simulated Ice Hockey Period.” 2018. Masters Thesis, San Jose State University. Accessed March 04, 2021.
https://doi.org/10.31979/etd.9pf7-9u25 ; https://scholarworks.sjsu.edu/etd_theses/4978.
MLA Handbook (7th Edition):
Rayfield, Kurtis Ryan. “Effects of Optimizing the Respiratory Pump on Performance During a Simulated Ice Hockey Period.” 2018. Web. 04 Mar 2021.
Vancouver:
Rayfield KR. Effects of Optimizing the Respiratory Pump on Performance During a Simulated Ice Hockey Period. [Internet] [Masters thesis]. San Jose State University; 2018. [cited 2021 Mar 04].
Available from: https://doi.org/10.31979/etd.9pf7-9u25 ; https://scholarworks.sjsu.edu/etd_theses/4978.
Council of Science Editors:
Rayfield KR. Effects of Optimizing the Respiratory Pump on Performance During a Simulated Ice Hockey Period. [Masters Thesis]. San Jose State University; 2018. Available from: https://doi.org/10.31979/etd.9pf7-9u25 ; https://scholarworks.sjsu.edu/etd_theses/4978
University of Alberta
14.
Yakimets, Joan M.
Impedance cardiography: comparison of NCCOM3-R7 to
thermodilution and fick methods.
Degree: Master in Nursing, Faculty of Nursing, 1993, University of Alberta
URL: https://era.library.ualberta.ca/files/fn107117f
Subjects/Keywords: Impedance plethysmography.
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Manager
APA (6th Edition):
Yakimets, J. M. (1993). Impedance cardiography: comparison of NCCOM3-R7 to
thermodilution and fick methods. (Masters Thesis). University of Alberta. Retrieved from https://era.library.ualberta.ca/files/fn107117f
Chicago Manual of Style (16th Edition):
Yakimets, Joan M. “Impedance cardiography: comparison of NCCOM3-R7 to
thermodilution and fick methods.” 1993. Masters Thesis, University of Alberta. Accessed March 04, 2021.
https://era.library.ualberta.ca/files/fn107117f.
MLA Handbook (7th Edition):
Yakimets, Joan M. “Impedance cardiography: comparison of NCCOM3-R7 to
thermodilution and fick methods.” 1993. Web. 04 Mar 2021.
Vancouver:
Yakimets JM. Impedance cardiography: comparison of NCCOM3-R7 to
thermodilution and fick methods. [Internet] [Masters thesis]. University of Alberta; 1993. [cited 2021 Mar 04].
Available from: https://era.library.ualberta.ca/files/fn107117f.
Council of Science Editors:
Yakimets JM. Impedance cardiography: comparison of NCCOM3-R7 to
thermodilution and fick methods. [Masters Thesis]. University of Alberta; 1993. Available from: https://era.library.ualberta.ca/files/fn107117f
University of Alberta
15.
AREFIFAR, SEYED ALI.
Online measurement and monitoring of power system impedance
and load model parameters.
Degree: PhD, Department of Electrical and Computer
Engineering, 2010, University of Alberta
URL: https://era.library.ualberta.ca/files/b5644t04m
► In power system studies, some parameters cannot be measured directly by using the currently existing power meters. These power system parameters include the power system…
(more)
▼ In power system studies, some parameters cannot be
measured directly by using the currently existing power meters.
These power system parameters include the power system Thevenin
impedance, harmonic impedances, zero sequence impedance, and the
load model parameters. The power system’s Thevenin impedance at a
load bus is an important parameter for power system planning and
operation. The effects of changing the system operation conditions
on voltages at the load buses can be easily determined if the power
system impedance parameters are known. Moreover, by knowing the
Thevenin equivalent parameters, one can calculate the system’s
voltage stability margin and maximum loadability. The knowledge of
power system harmonic impedances is necessary for harmonic
mitigation, determination of harmonic limit compliance, prediction
of system resonance, and harmonic propagation studies. Moreover,
real-time monitoring of the system’s harmonic impedances provides
significant improvements to the design and operation of active
filters. The system’s zero sequence impedance at the substation bus
is also important information for power system studies. It is used
to calculate the different ground fault levels at substations.
Furthermore, the loads in power systems play a significant role in
power system planning, control, and stability analysis. Having
reliable and accurate models of the loads is essential for
designing automatic control systems and optimizing their
configuration. Obtaining such models has been a challenging problem
for power system engineers for decades, especially in the current
deregulated market environment. This thesis presents newly
developed and verified algorithms for online measurement and
monitoring of these power system parameters. The algorithm proposed
for monitoring the system’s Thevenin, harmonic, and zero sequence
impedance parameters, uses the natural variations of the loads
connected to the substations. The proposed algorithm for monitoring
of load model parameters uses the voltage and current waveforms
captured during the operation of the Under Load Tap Change (ULTC)
transformers installed in the distribution substations. The
proposed algorithms are applied to several field measurements from
different substations. The results show that the algorithms fulfill
the requirements for the online measurement and monitoring of power
system Thevenin, harmonic and zero sequence impedances as well as
the load model parameters.
Subjects/Keywords: load modeling; impedance measurement
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
AREFIFAR, S. A. (2010). Online measurement and monitoring of power system impedance
and load model parameters. (Doctoral Dissertation). University of Alberta. Retrieved from https://era.library.ualberta.ca/files/b5644t04m
Chicago Manual of Style (16th Edition):
AREFIFAR, SEYED ALI. “Online measurement and monitoring of power system impedance
and load model parameters.” 2010. Doctoral Dissertation, University of Alberta. Accessed March 04, 2021.
https://era.library.ualberta.ca/files/b5644t04m.
MLA Handbook (7th Edition):
AREFIFAR, SEYED ALI. “Online measurement and monitoring of power system impedance
and load model parameters.” 2010. Web. 04 Mar 2021.
Vancouver:
AREFIFAR SA. Online measurement and monitoring of power system impedance
and load model parameters. [Internet] [Doctoral dissertation]. University of Alberta; 2010. [cited 2021 Mar 04].
Available from: https://era.library.ualberta.ca/files/b5644t04m.
Council of Science Editors:
AREFIFAR SA. Online measurement and monitoring of power system impedance
and load model parameters. [Doctoral Dissertation]. University of Alberta; 2010. Available from: https://era.library.ualberta.ca/files/b5644t04m
University of Alberta
16.
Kalainy, Sylvia AR.
Fluid volume assessment in hemodialysis patients.
Degree: MS, Department of Medicine, 2015, University of Alberta
URL: https://era.library.ualberta.ca/files/jw827f01m
► Achievement of normal volume status is crucial in hemodialysis (HD), since both volume overload and volume depletion have been associated with adverse outcome and events.…
(more)
▼ Achievement of normal volume status is crucial in
hemodialysis (HD), since both volume overload and volume depletion
have been associated with adverse outcome and events. The main
objectives of this thesis were to find out the prevalence of volume
overload and to identify the best clinical parameter or set of
parameters that can predict volume overload in HD patients along
with the development of volume management protocol. Another
objective was investigating the literature about the use of sodium
profiling in alleviating intradialytic side effects. Volume status
of 194 HD patients in 2 hemodialysis units was assessed by
multi-frequency bio-impedance spectroscopy. Of all patients 48%
(n=94) were volume expanded. ECFV depletion was present in 9% of
patients (n=17). Interdialytic weight gain (IDWG) was not different
between hypovolemic, normovolemic and hypervolemic patients. Only
50% of the volume overloaded patients were hypertensive
(>140/90mmHg). Paradoxical hypertension was common (31% of
all patients) in our HD population, however, its incidence was not
different between patients. Intradialytic hypotension was
relatively common and was more frequent amongst hypovolemic
patients. Blood pressure was neither sensitive nor specific for
volume assessment. Edema was highly specific for detection of
volume overload but lacks sensitivity. In sum, the study indicates
that volume overload is highly prevalent in HD population and could
not be identified using clinical parameters alone. Only 4 clinical
parameters (edema, SBP, lower BMI, smoking) were found to be
significant predictors for volume overload. None of the 4
parameters was sensitive and specific. We found that bio-impedance
was a helpful bedside method to better identify hidden volume
overload.
Subjects/Keywords: Hemodialysis; Volume assessment; bio-impedance
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Manager
APA (6th Edition):
Kalainy, S. A. (2015). Fluid volume assessment in hemodialysis patients. (Masters Thesis). University of Alberta. Retrieved from https://era.library.ualberta.ca/files/jw827f01m
Chicago Manual of Style (16th Edition):
Kalainy, Sylvia AR. “Fluid volume assessment in hemodialysis patients.” 2015. Masters Thesis, University of Alberta. Accessed March 04, 2021.
https://era.library.ualberta.ca/files/jw827f01m.
MLA Handbook (7th Edition):
Kalainy, Sylvia AR. “Fluid volume assessment in hemodialysis patients.” 2015. Web. 04 Mar 2021.
Vancouver:
Kalainy SA. Fluid volume assessment in hemodialysis patients. [Internet] [Masters thesis]. University of Alberta; 2015. [cited 2021 Mar 04].
Available from: https://era.library.ualberta.ca/files/jw827f01m.
Council of Science Editors:
Kalainy SA. Fluid volume assessment in hemodialysis patients. [Masters Thesis]. University of Alberta; 2015. Available from: https://era.library.ualberta.ca/files/jw827f01m
University of Manchester
17.
Cao, Gaoxiang.
Multi-functional epoxy/graphene nanoplatelet
composites.
Degree: 2016, University of Manchester
URL: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:301217
► Graphene nanoplatelets (GNP) with thickness of 6 ~ 8 nm and lateral dimension of 5 μm (M5) and 25 μm (M25) have been used to…
(more)
▼ Graphene nanoplatelets (GNP) with thickness of 6 ~
8 nm and lateral dimension of 5 μm (M5) and 25 μm (M25) have been
used to prepare epoxy composites. Epoxy composites were fabricated
initially by shear mixing to investigate the effects of filler type
on the structure and properties of composites. The complex
viscosity of GNP-epoxy mixture was found to increase by almost
three orders of magnitude going from the neat epoxy to the 8 wt.%
loading, leading to difficulties in their processing. Scanning
electron microscopy of the composites showed that both fillers
aggregated at high loadings with the M25 buckling more easily due
to its larger diameter, which compromises its aspect ratio
advantage over M5, resulting in only slightly better mechanical
performance. Polarized Raman spectroscopy revealed that both M5 and
M25 were randomly distributed in the epoxy matrix, After adding M5
and M25 fillers, the storage modulus increase with the filler
loadings, however, the glass transition temperature (Tg) drops
slightly after initial incorporation, then rises with further
filler addition attributed to the pin effects of filler
aggregations. In terms of electrical property, M25 has lower
percolation (1 wt.%) than M5 composites due to its bigger aspect
ratio, which enable M25 to form a conductive network more
efficiently. Furthermore, M25 composites also have slightly better
thermal and mechanical properties over that of M5 composites.
However, the difference is not significant considering the aspect
ratio of M25 is five times of that of M5. The reason is that the
aggregation and buckling of M25 compromise its advantage over M5.
Due to the better performance of M25 as filler, M25/epoxy
composites were prepared by shear mixing, solvent compounding and
three-roll mill. Samples made by solvent compounding display the
lowest percolation threshold (0.5 wt.%), related to its relatively
uniform dispersion of M25 in matrix, resulting in higher thermal
conductivity and better mechanical properties. Water uptake in a
water bath at 50 °C took 75 days to be saturated. Higher loaded
samples have lower diffusion coefficient because of the barrier
effects of GNP fillers, but have higher maximum water absorbed,
which is owing to filler aggregation. Properties test of aged and
unaged specimens show thermal conductivity of the aged was enhanced
due to water’s higher thermal conductivity than epoxy resin matrix,
while electrical performance was compromised due to the swelling
effects caused by absorbed water. The mechanical properties of aged
samples also dropped slightly due to plasticization
effects.
Advisors/Committee Members: YOUNG, ROBERT RJ, Young, Robert, Kinloch, Ian.
Subjects/Keywords: Eopxy; Graphene nanoplatelet; composites; Impedance
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APA (6th Edition):
Cao, G. (2016). Multi-functional epoxy/graphene nanoplatelet
composites. (Doctoral Dissertation). University of Manchester. Retrieved from http://www.manchester.ac.uk/escholar/uk-ac-man-scw:301217
Chicago Manual of Style (16th Edition):
Cao, Gaoxiang. “Multi-functional epoxy/graphene nanoplatelet
composites.” 2016. Doctoral Dissertation, University of Manchester. Accessed March 04, 2021.
http://www.manchester.ac.uk/escholar/uk-ac-man-scw:301217.
MLA Handbook (7th Edition):
Cao, Gaoxiang. “Multi-functional epoxy/graphene nanoplatelet
composites.” 2016. Web. 04 Mar 2021.
Vancouver:
Cao G. Multi-functional epoxy/graphene nanoplatelet
composites. [Internet] [Doctoral dissertation]. University of Manchester; 2016. [cited 2021 Mar 04].
Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:301217.
Council of Science Editors:
Cao G. Multi-functional epoxy/graphene nanoplatelet
composites. [Doctoral Dissertation]. University of Manchester; 2016. Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:301217
University of Manchester
18.
Quraishi, Tanviha.
Clinical Applications of Electrical Impedance
Tomography.
Degree: 2017, University of Manchester
URL: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:308659
► INTRODUCTION Electrical Impedance Tomography (EIT) is an emerging clinical imaging technique. Functional EIT by Evoked Response (fEITER) was developed at the University of Manchester as…
(more)
▼ INTRODUCTION Electrical
Impedance Tomography (EIT)
is an emerging clinical imaging technique. Functional EIT by Evoked
Response (fEITER) was developed at the University of Manchester as
a high-speed, functional brain imaging device for use at the
bedside. This 32-electrode EIT system applies an injection
frequency of 10kHz and captures data using a 10ms temporal
resolution. This thesis reports on the first volunteer and patient
trials undertaken using fEITER for the following conditions: (a)
flashing visual sequence - 14 awake volunteers; (b) a voluntary
Valsalva manoeuvre (VM) - 15 awake volunteers and (c) during the
induction of anaesthesia - 16 elective surgical patients.AIMS The
research presented in this thesis was undertaken to differentiate
between noise and physiological changes in raw fEITER data
signals.METHODS SNR was determined for fEITER. Raw fEITER signals
were pre-processed to reduce noise and dominant trends before
multiple comparisons between reference and stimulus data were
undertaken. Histograms and ROC curves were produced to illustrate
the difference between reference and stimulus fEITER data. AUC
values for single-
subject and pooled ROC curves were calculated to
determine whether fEITER data can be reliably differentiated
between reference and stimulus conditions. Approximate Entropy
(ApEn) was applied to evaluate the regularity of high frequency
components within fEITER data for each trial condition.RESULTS
Average SNR values for fEITER acquired using mesh and physical
phantoms ranged from 62.94dB to 63.58dB, and 28.29dB to 31.45dB
respectively. The following AUC values were acquired: Visual
stimulus-frontal electrode pairs and electrode pairs overlying the
visual cortex 0.520 and 0.505 respectively; VM: 0.658; and
induction of anaesthesia: 0.547. The VM induced the greatest
difference between pooled reference and stimulus data. Visual
stimulation and induction of anaesthesia data showed poor
distinction between pooled reference and stimulus data, although
some single
subject data did show a significant response. No
significant differences were acquired for the comparison of
ApEn-reference and ApEn-stimulus data for all trial conditions
using a Wilcoxon’s signed ranks test (visual stimulus-frontal
electrode pairs: upper p = 0.998, visual stimulus-electrode
overlying the visual cortex: upper p = 0.980; the VM: upper p =
0.976, and induction of anaesthesia: p = 0.912).DISCUSSION Although
single-
subject and pooled fEITER data recorded during the VM
produced the greatest differences between reference and stimulus
measurements, stimuli such as visual flashes and induction of
anaesthesia may not be large enough to induce quantifiable changes
between reference and stimulus data recorded from single electrode
pairs.Collectively, these results provide little evidence to show
that pre-processing of raw fEITER data amplifies features in fEITER
waveforms which may be representative of physiological changes
induced by an applied stimulus.
Advisors/Committee Members: POLLARD, BRIAN BJ, MARCHANT, THOMAS T, Pollard, Brian, Bryan, Angella, Marchant, Thomas.
Subjects/Keywords: Electrical Impedance Tomography; Brain
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Manager
APA (6th Edition):
Quraishi, T. (2017). Clinical Applications of Electrical Impedance
Tomography. (Doctoral Dissertation). University of Manchester. Retrieved from http://www.manchester.ac.uk/escholar/uk-ac-man-scw:308659
Chicago Manual of Style (16th Edition):
Quraishi, Tanviha. “Clinical Applications of Electrical Impedance
Tomography.” 2017. Doctoral Dissertation, University of Manchester. Accessed March 04, 2021.
http://www.manchester.ac.uk/escholar/uk-ac-man-scw:308659.
MLA Handbook (7th Edition):
Quraishi, Tanviha. “Clinical Applications of Electrical Impedance
Tomography.” 2017. Web. 04 Mar 2021.
Vancouver:
Quraishi T. Clinical Applications of Electrical Impedance
Tomography. [Internet] [Doctoral dissertation]. University of Manchester; 2017. [cited 2021 Mar 04].
Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:308659.
Council of Science Editors:
Quraishi T. Clinical Applications of Electrical Impedance
Tomography. [Doctoral Dissertation]. University of Manchester; 2017. Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:308659
Texas A&M University
19.
Huang, Hao.
Impedance Spectroscopy Systems Suitable for Biomedical Cell Impedance Measurement.
Degree: MS, Electrical Engineering, 2013, Texas A&M University
URL: http://hdl.handle.net/1969.1/151036
► Impedance spectroscopy (IS) is an important technique for monitoring and detection of biomaterials. In order to enable point-of-care systems, low-cost IS systems capable of rapidly…
(more)
▼ Impedance spectroscopy (IS) is an important technique for monitoring and detection of biomaterials. In order to enable point-of-care systems, low-cost IS systems capable of rapidly measuring a wide range of biomaterials are required. This thesis presents two IS systems, one in Printed Circuit Board level and the other in Integrated Circuit level.
The board level system is built for preliminary experimental data collection; it is capable of measuring
impedance from 1KHz to 100KHz with 200mV signal injection into cell sample. Experimental results show that magnitude and phase error are less than 6.6% and 2.2%, respectively.
An IC level IS front-end is also proposed which utilizes a time-to-digital converter (TDC) and a peak detector circuit (PDC) for quick measurement of both
impedance phase and magnitude, respectively. Designed in a 0.18μm CMOS process, the front-end is capable of performing
impedance measurements in 6μs at frequencies ranging from 100Hz-10MHz and with a 100Ω-1MΩ dynamic range. Simulation results with cell
impedance models show that the system achieves <2.5% magnitude and <2.2 degree phase error. The front-end consumes 28mW total power and occupies 0.4mm
2 area.
Advisors/Committee Members: Palermo, Samuel (advisor), Banerjee, Debjyoti (committee member), Kamran, Entesari (committee member), Jun, Kameoka (committee member).
Subjects/Keywords: Impedance Spectroscopy; CMOS; biomedical
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APA (6th Edition):
Huang, H. (2013). Impedance Spectroscopy Systems Suitable for Biomedical Cell Impedance Measurement. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/151036
Chicago Manual of Style (16th Edition):
Huang, Hao. “Impedance Spectroscopy Systems Suitable for Biomedical Cell Impedance Measurement.” 2013. Masters Thesis, Texas A&M University. Accessed March 04, 2021.
http://hdl.handle.net/1969.1/151036.
MLA Handbook (7th Edition):
Huang, Hao. “Impedance Spectroscopy Systems Suitable for Biomedical Cell Impedance Measurement.” 2013. Web. 04 Mar 2021.
Vancouver:
Huang H. Impedance Spectroscopy Systems Suitable for Biomedical Cell Impedance Measurement. [Internet] [Masters thesis]. Texas A&M University; 2013. [cited 2021 Mar 04].
Available from: http://hdl.handle.net/1969.1/151036.
Council of Science Editors:
Huang H. Impedance Spectroscopy Systems Suitable for Biomedical Cell Impedance Measurement. [Masters Thesis]. Texas A&M University; 2013. Available from: http://hdl.handle.net/1969.1/151036
University of Waterloo
20.
Schmidt, Jesse.
CMOS Electrochemical Camera for Biological Cell Impedance Imaging.
Degree: 2019, University of Waterloo
URL: http://hdl.handle.net/10012/14812
► Many biomedical applications require observing the response of biological cells to various stimuli and conditions. Typical optical imaging systems for observing cells require labelling cells…
(more)
▼ Many biomedical applications require observing the response of biological cells to various stimuli and conditions. Typical optical imaging systems for observing cells require labelling cells with fluorescent molecules. These systems have drawbacks such as limited luminescence time and light-induced damage. However, use of electrochemical based measurement methods overcome these issues. One method, which is label-free and non-invasive, is impedance spectroscopy (IS), which tracks impedance changes caused by variations in cell membrane properties.
This thesis describes the design and experimental characterization of a CMOS electrochemical camera for biological cell impedance imaging. The electrochemical camera is fabricated in a 0.18-um CMOS technology, and is the first to implement a row-parallel architecture which improves upon spatial-readout efficiency compared to previously published work. Two integrated microelectrode arrays, one containing 17x11 40x40 um2 electrodes and the other containing 70x40 10x10 um2 electrodes, are implemented. Each array is connected to 84 integrated row-parallel lock-in amplifiers to measure the impedance of live cells on the electrode array surface. A novel lock-in amplifier design allows for an electrode pitch of only 20 um. The design of a custom bench-top measurement system for characterizing the performance of the CMOS electrochemical camera is also described.
Experimental electronic characterization of the electrochemical camera shows that it
can operate from 1 kHz to 1 MHz at a frame rate of 0.0117 Hz, which is sufficient for
several cell imaging applications. The measured input-referred noise is 1.08 nArms with an
applied input signal at 600 kHz. Compared to previously reported CMOS electrochemical
sensor arrays, the presented work consumes the smallest channel area for the sensor readout
electronics with integrated analog-to-digital converter, the lowest power consumption per
channel for operating frequencies greater than 100 kHz, and the best area-readout figure of merit.
Subjects/Keywords: CMOS; camera; impedance; biological; cell
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APA (6th Edition):
Schmidt, J. (2019). CMOS Electrochemical Camera for Biological Cell Impedance Imaging. (Thesis). University of Waterloo. Retrieved from http://hdl.handle.net/10012/14812
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Schmidt, Jesse. “CMOS Electrochemical Camera for Biological Cell Impedance Imaging.” 2019. Thesis, University of Waterloo. Accessed March 04, 2021.
http://hdl.handle.net/10012/14812.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Schmidt, Jesse. “CMOS Electrochemical Camera for Biological Cell Impedance Imaging.” 2019. Web. 04 Mar 2021.
Vancouver:
Schmidt J. CMOS Electrochemical Camera for Biological Cell Impedance Imaging. [Internet] [Thesis]. University of Waterloo; 2019. [cited 2021 Mar 04].
Available from: http://hdl.handle.net/10012/14812.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Schmidt J. CMOS Electrochemical Camera for Biological Cell Impedance Imaging. [Thesis]. University of Waterloo; 2019. Available from: http://hdl.handle.net/10012/14812
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
University of Toronto
21.
Wei, Yuan.
Impedance Spectroscopy of Single Cells Using Embedded AgPDMS Electrodes.
Degree: 2015, University of Toronto
URL: http://hdl.handle.net/1807/70693
► This thesis presents a microfluidic device with wide channels and embedded AgPDMS electrodes for measuring the electrical properties of single cells. The work demonstrates the…
(more)
▼ This thesis presents a microfluidic device with wide channels and embedded AgPDMS electrodes for measuring the electrical properties of single cells. The work demonstrates the feasibility of using a large channel design and embedded electrodes for impedance spectroscopy to circumvent issues such as channel clogging and limited device re-usability. AgPDMS electrodes were formed on channel sidewalls for impedance detection and cell characterization. Equivalent circuit models were used to interpret multi-frequency impedance data to quantify the cytoplasm conductivity and specific membrane capacitance of each cell. T24 cells were tested to validate the microfluidic system and modeling results. Comparisons were then made by measuring two leukemia cell lines (AML-2 and HL-60) which were found to have different cytoplasm conductivity values (0.29 ± 0.15 S/m vs. 0.47 ± 0.20 S/m) and specific membrane capacitance values (41 ± 25 mF/m2 vs. 55 ± 26 mF/m2).
M.A.S.
Advisors/Committee Members: Sun, Yu, Mechanical and Industrial Engineering.
Subjects/Keywords: Cells; Impedance spectroscopy; Microfluidics; 0548
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APA (6th Edition):
Wei, Y. (2015). Impedance Spectroscopy of Single Cells Using Embedded AgPDMS Electrodes. (Masters Thesis). University of Toronto. Retrieved from http://hdl.handle.net/1807/70693
Chicago Manual of Style (16th Edition):
Wei, Yuan. “Impedance Spectroscopy of Single Cells Using Embedded AgPDMS Electrodes.” 2015. Masters Thesis, University of Toronto. Accessed March 04, 2021.
http://hdl.handle.net/1807/70693.
MLA Handbook (7th Edition):
Wei, Yuan. “Impedance Spectroscopy of Single Cells Using Embedded AgPDMS Electrodes.” 2015. Web. 04 Mar 2021.
Vancouver:
Wei Y. Impedance Spectroscopy of Single Cells Using Embedded AgPDMS Electrodes. [Internet] [Masters thesis]. University of Toronto; 2015. [cited 2021 Mar 04].
Available from: http://hdl.handle.net/1807/70693.
Council of Science Editors:
Wei Y. Impedance Spectroscopy of Single Cells Using Embedded AgPDMS Electrodes. [Masters Thesis]. University of Toronto; 2015. Available from: http://hdl.handle.net/1807/70693
Oregon State University
22.
Sternes, Kenneth James.
Impedance bridge balancing using perturbation theory.
Degree: MS, Electrical and Electronics Engineering, 1967, Oregon State University
URL: http://hdl.handle.net/1957/47293
► This paper describes a technique for separating the two signal voltages which are necessary for balancing an ac impedance bridge from its detector output voltage.…
(more)
▼ This paper describes a technique for separating the
two signal voltages which are necessary for balancing an
ac
impedance bridge from its detector output voltage.
The technique is unique in that the necessary information
is derived from modulations on the generator voltage.
These modulations are formed by perturbing the variable
arms at a fixed frequency but phased 90° apart. The two
signals are then separated by phase detectors referenced
to the modulation frequency and the proper phase. The
perturbation increases and decreases the arm by a small
amount; comparable to the action of a human operator
increasing and decreasing the variable arm slightly to
see which direction appears to lead to a null. Although
no attempt was made to automate a bridge, this paper
discusses the theoretical considerations for deriving
the proper control signals for automating a bridge as
well as experimental results obtained from a working
model of such a system.
Advisors/Committee Members: Looney, James C. (advisor).
Subjects/Keywords: Impedance (Electricity)
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APA (6th Edition):
Sternes, K. J. (1967). Impedance bridge balancing using perturbation theory. (Masters Thesis). Oregon State University. Retrieved from http://hdl.handle.net/1957/47293
Chicago Manual of Style (16th Edition):
Sternes, Kenneth James. “Impedance bridge balancing using perturbation theory.” 1967. Masters Thesis, Oregon State University. Accessed March 04, 2021.
http://hdl.handle.net/1957/47293.
MLA Handbook (7th Edition):
Sternes, Kenneth James. “Impedance bridge balancing using perturbation theory.” 1967. Web. 04 Mar 2021.
Vancouver:
Sternes KJ. Impedance bridge balancing using perturbation theory. [Internet] [Masters thesis]. Oregon State University; 1967. [cited 2021 Mar 04].
Available from: http://hdl.handle.net/1957/47293.
Council of Science Editors:
Sternes KJ. Impedance bridge balancing using perturbation theory. [Masters Thesis]. Oregon State University; 1967. Available from: http://hdl.handle.net/1957/47293
University of Connecticut
23.
Cremins, Matthew D.
Fault Detection in Railway Track Using Piezoelectric Impedance.
Degree: MS, Mechanical Engineering, 2014, University of Connecticut
URL: https://opencommons.uconn.edu/gs_theses/630
► In this thesis, piezoelectric transducers are incorporated in an impedance-based damage detection approach for railway track health monitoring. The impedance-based damage detection approach utilizes…
(more)
▼ In this thesis, piezoelectric transducers are incorporated in an
impedance-based damage detection approach for railway track health monitoring. The
impedance-based damage detection approach utilizes the direct relationship between the mechanical
impedance of the track and electrical
impedance of the piezoelectric transducer bonded. The effect of damage is shown in the change of a healthy
impedance curve to an altered, damaged curve. Using a normalized relative difference outlier analysis, the occurrences of various damages on the track are determined. Furthermore, the integration of inductive circuitry with the piezoelectric transducer is found to be able to considerably increase overall damage detection sensitivity.
Advisors/Committee Members: Prof. Shinae Jang, Prof. Robert Gao, Prof. Jiong Tang.
Subjects/Keywords: Railway Track; Impedance; Health Monitoring
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APA (6th Edition):
Cremins, M. D. (2014). Fault Detection in Railway Track Using Piezoelectric Impedance. (Masters Thesis). University of Connecticut. Retrieved from https://opencommons.uconn.edu/gs_theses/630
Chicago Manual of Style (16th Edition):
Cremins, Matthew D. “Fault Detection in Railway Track Using Piezoelectric Impedance.” 2014. Masters Thesis, University of Connecticut. Accessed March 04, 2021.
https://opencommons.uconn.edu/gs_theses/630.
MLA Handbook (7th Edition):
Cremins, Matthew D. “Fault Detection in Railway Track Using Piezoelectric Impedance.” 2014. Web. 04 Mar 2021.
Vancouver:
Cremins MD. Fault Detection in Railway Track Using Piezoelectric Impedance. [Internet] [Masters thesis]. University of Connecticut; 2014. [cited 2021 Mar 04].
Available from: https://opencommons.uconn.edu/gs_theses/630.
Council of Science Editors:
Cremins MD. Fault Detection in Railway Track Using Piezoelectric Impedance. [Masters Thesis]. University of Connecticut; 2014. Available from: https://opencommons.uconn.edu/gs_theses/630
University of Manchester
24.
Quraishi, Tanviha.
Clinical applications of Electrical Impedance Tomography.
Degree: PhD, 2017, University of Manchester
URL: https://www.research.manchester.ac.uk/portal/en/theses/clinical-applications-of-electrical-impedance-tomography(bfe18e6f-e9e3-49ff-9f5b-4b0bbf72c575).html
;
http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.713632
► Introduction: Electrical Impedance Tomography (EIT) is an emerging clinical imaging technique. Functional EIT by Evoked Response (fEITER) was developed at the University of Manchester as…
(more)
▼ Introduction: Electrical Impedance Tomography (EIT) is an emerging clinical imaging technique. Functional EIT by Evoked Response (fEITER) was developed at the University of Manchester as a high-speed, functional brain imaging device for use at the bedside. This 32-electrode EIT system applies an injection frequency of 10kHz and captures data using a 10ms temporal resolution. This thesis reports on the first volunteer and patient trials undertaken using fEITER for the following conditions: (a) flashing visual sequence - 14 awake volunteers; (b) a voluntary Valsalva manoeuvre (VM) - 15 awake volunteers and (c) during the induction of anaesthesia - 16 elective surgical patients. Aims: The research presented in this thesis was undertaken to differentiate between noise and physiological changes in raw fEITER data signals. Methods: SNR was determined for fEITER. Raw fEITER signals were pre-processed to reduce noise and dominant trends before multiple comparisons between reference and stimulus data were undertaken. Histograms and ROC curves were produced to illustrate the difference between reference and stimulus fEITER data. AUC values for single-subject and pooled ROC curves were calculated to determine whether fEITER data can be reliably differentiated between reference and stimulus conditions. Approximate Entropy (ApEn) was applied to evaluate the regularity of high frequency components within fEITER data for each trial condition. Results: Average SNR values for fEITER acquired using mesh and physical phantoms ranged from 62.94dB to 63.58dB, and 28.29dB to 31.45dB respectively. The following AUC values were acquired: Visual stimulus-frontal electrode pairs and electrode pairs overlying the visual cortex 0.520 and 0.505 respectively; VM: 0.658; and induction of anaesthesia: 0.547. The VM induced the greatest difference between pooled reference and stimulus data. Visual stimulation and induction of anaesthesia data showed poor distinction between pooled reference and stimulus data, although some single subject data did show a significant response. No significant differences were acquired for the comparison of ApEn-reference and ApEn-stimulus data for all trial conditions using a Wilcoxon's signed ranks test (visual stimulus-frontal electrode pairs: upper p = 0.998, visual stimulus-electrode overlying the visual cortex: upper p = 0.980; the VM: upper p = 0.976, and induction of anaesthesia: p = 0.912). Discussion: Although single-subject and pooled fEITER data recorded during the VM produced the greatest differences between reference and stimulus measurements, stimuli such as visual flashes and induction of anaesthesia may not be large enough to induce quantifiable changes between reference and stimulus data recorded from single electrode pairs. Collectively, these results provide little evidence to show that pre-processing of raw fEITER data amplifies features in fEITER waveforms which may be representative of physiological changes induced by an applied stimulus.
Subjects/Keywords: 616.07; Electrical Impedance Tomography; Brain
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APA (6th Edition):
Quraishi, T. (2017). Clinical applications of Electrical Impedance Tomography. (Doctoral Dissertation). University of Manchester. Retrieved from https://www.research.manchester.ac.uk/portal/en/theses/clinical-applications-of-electrical-impedance-tomography(bfe18e6f-e9e3-49ff-9f5b-4b0bbf72c575).html ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.713632
Chicago Manual of Style (16th Edition):
Quraishi, Tanviha. “Clinical applications of Electrical Impedance Tomography.” 2017. Doctoral Dissertation, University of Manchester. Accessed March 04, 2021.
https://www.research.manchester.ac.uk/portal/en/theses/clinical-applications-of-electrical-impedance-tomography(bfe18e6f-e9e3-49ff-9f5b-4b0bbf72c575).html ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.713632.
MLA Handbook (7th Edition):
Quraishi, Tanviha. “Clinical applications of Electrical Impedance Tomography.” 2017. Web. 04 Mar 2021.
Vancouver:
Quraishi T. Clinical applications of Electrical Impedance Tomography. [Internet] [Doctoral dissertation]. University of Manchester; 2017. [cited 2021 Mar 04].
Available from: https://www.research.manchester.ac.uk/portal/en/theses/clinical-applications-of-electrical-impedance-tomography(bfe18e6f-e9e3-49ff-9f5b-4b0bbf72c575).html ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.713632.
Council of Science Editors:
Quraishi T. Clinical applications of Electrical Impedance Tomography. [Doctoral Dissertation]. University of Manchester; 2017. Available from: https://www.research.manchester.ac.uk/portal/en/theses/clinical-applications-of-electrical-impedance-tomography(bfe18e6f-e9e3-49ff-9f5b-4b0bbf72c575).html ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.713632
University of Bath
25.
Chen, Bo.
Electrical Resistance Tomography for multiphase flow in water industry.
Degree: PhD, 2019, University of Bath
URL: https://researchportal.bath.ac.uk/en/studentthesis/electrical-resistance-tomography-for-multiphase-flow-in-water-industry(b63192db-d03f-4152-9155-993fe1176b73).html
;
https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.782240
► The main purpose of this thesis is to develop a better understanding of the interfaces between materials in spatial and time domains via 2D and…
(more)
▼ The main purpose of this thesis is to develop a better understanding of the interfaces between materials in spatial and time domains via 2D and 3D visualisation and quantitative parameter measurement using Electrical Resistance Tomography (ERT). Some advantages of ERT have been reported as being high temporal resolution, low-cost and non-radiation emitting. The ERT modality is generally used to visualise the interior of a region by mapping the conductivity distribution using potential difference that is measured by electrodes that are attached to the medium. The main algorithm for image reconstruction that has been used is total variation regularisation due to its potential for producing high-quality images with sharp boundaries. In this work, a series of simulation studies and lab-based phantom experimental tests were conducted. Contributions of this thesis are generally categorised into three aspects. First of all, a spatial-temporal total variation based on the Split Bregman method has been proposed for analysing dynamical movement of a target in a circular tank based on 2D ERT, where spatial and temporal gradients were employed for exploring performance in the space and time domains, and time response of dynamical ERT images has been proposed for the comparison and illustration of advantages of sharp dynamical images. Furthermore, the proposed STTV has extended to 3D ERT visualisation, where a tank with the shape of a vertical pipe has been designed with a dual-plane aiming at representing interior information by producing dynamical images of a moving target inside the pipe. Velocity measurements are feasible based on 2D/3D ERT and the cross correlation method, and the accuracy of these were discussed. Moreover, planar array for 3D ERT visualisation was used to overcome the issue that 3D ERT visualisations based on traditional electrode-ring sensors would suffer from low resolution on the axis-direction along the pipe, especially the region between rings where electrode-ring gaps lead to missing data. Results showed that ERT planar array can extract additional information in its detectable region with a higher 3D spatial resolution, and a combination of planar array and ring-electrode ERT can potentially be made for the purpose of exploring more information in a pipeline. In general, this thesis represents the research works on improving the performance of static/dynamical ERT visualisation and quantitative parameter measurements. These works have potential applications in flow imaging and tomography-based measurement or control systems in the future. Detailed applications and further work are suggested. Although ERT is a new imaging technique and lots of issues are still preserved to be solved, it is believed that such research would have contributions to the future development of electrical impedance tomography research.
Subjects/Keywords: 621.3; Electrical impedance tomography
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Manager
APA (6th Edition):
Chen, B. (2019). Electrical Resistance Tomography for multiphase flow in water industry. (Doctoral Dissertation). University of Bath. Retrieved from https://researchportal.bath.ac.uk/en/studentthesis/electrical-resistance-tomography-for-multiphase-flow-in-water-industry(b63192db-d03f-4152-9155-993fe1176b73).html ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.782240
Chicago Manual of Style (16th Edition):
Chen, Bo. “Electrical Resistance Tomography for multiphase flow in water industry.” 2019. Doctoral Dissertation, University of Bath. Accessed March 04, 2021.
https://researchportal.bath.ac.uk/en/studentthesis/electrical-resistance-tomography-for-multiphase-flow-in-water-industry(b63192db-d03f-4152-9155-993fe1176b73).html ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.782240.
MLA Handbook (7th Edition):
Chen, Bo. “Electrical Resistance Tomography for multiphase flow in water industry.” 2019. Web. 04 Mar 2021.
Vancouver:
Chen B. Electrical Resistance Tomography for multiphase flow in water industry. [Internet] [Doctoral dissertation]. University of Bath; 2019. [cited 2021 Mar 04].
Available from: https://researchportal.bath.ac.uk/en/studentthesis/electrical-resistance-tomography-for-multiphase-flow-in-water-industry(b63192db-d03f-4152-9155-993fe1176b73).html ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.782240.
Council of Science Editors:
Chen B. Electrical Resistance Tomography for multiphase flow in water industry. [Doctoral Dissertation]. University of Bath; 2019. Available from: https://researchportal.bath.ac.uk/en/studentthesis/electrical-resistance-tomography-for-multiphase-flow-in-water-industry(b63192db-d03f-4152-9155-993fe1176b73).html ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.782240
University of Manchester
26.
Othman, Raja.
Synthesis and characterisation of hybrid carbon-nanotube silica microparticles.
Degree: PhD, 2012, University of Manchester
URL: https://www.research.manchester.ac.uk/portal/en/theses/synthesis-and-characterisation-of-hybrid-carbon –
nanotube-silica-microparticles(8975f54b-b679-407d-84b0-99d4d67e6efd).html
;
http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.564314
► Carbon nanotubes (CNTs) have been successfully grafted onto the surfaces of spherical silica gels via a floating-catalyst chemical vapour deposition method. Two types of silica…
(more)
▼ Carbon nanotubes (CNTs) have been successfully grafted onto the surfaces of spherical silica gels via a floating-catalyst chemical vapour deposition method. Two types of silica gels were used as substrates; SG6 (6 – 8 nm pore size) and SG26 (26 – 34 nm pore size). The optimum growth conditions were found to be 760 °C growth temperature, 3 hours growth time, and 5 wt .% of ferrocene catalyst (dissolved in toluene) injected into the furnace at a rate of 0.04 ml/min. Under these conditions, CNTs coated the exterior surface of the gels with growth occurring from both the pores and from the surface. The geometry and porosity of the silica gel were also found to influence the alignment and density of the grafted CNTs, with SG6 producing the best quality hybrid particle under the above conditions (labelled SG6_3). Thermal Gravimetric Analysis showed the yield of CNTs grown under these optimum condition was 33.6 + 0.37 wt. %. As the CNTs remained strongly attached to the surface of the gel, the grafting process produced excellent dispersion of the CNTs within polymer matrices as CNT bundle formation was prevented. The inclusion of micron size silica introduced a large excluded volume within polymer matrices, with the dispersion of CNTs restricted to a region along the silica surface. This arrangement aided the formation of an electrically conductive network in a poly (vinyl) alcohol matrix, where the critical percolation threshold (pc) was calculated as 0.62 wt. % of SG6_3, equivalent to a CNT content of 0.2 wt. %.The inclusion of SG6_3 into an epoxy resin suspension did not alter the rheological behaviour of the resin up to the highest loading employed (5 wt. %, ≈1.65 wt. % of CNTs). Within the linear viscoelastic region the viscoelastic moduli of the neat resin remained within the same magnitude, whilst the addition of 1.65 wt. % of commercially available CNTs into the same resin increased the storage and loss moduli by up to seven and three orders of magnitude, respectively. The complex viscosity of the suspension remained unchanged regardless of the amount of SG6_3 added; whereas an increase in viscosity of up to five orders of magnitude resulted from the addition of 1.65 wt. % non – grafted CNTs.Grafting of CNTs onto the surface of micron size spherical silica gel has been shown to provide a means of incorporating CNTs into a polymer without increasing viscosity. In addition, the SG6_3 also formed an electrically-conductive percolated network in an epoxy resin composite at low levels of addition, with pc = 0.16 wt. % of CNTs (i.e. 0.5 wt. % SG6_3).
Subjects/Keywords: 620.5; Rheology; Carbon Nanotube; Impedance
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APA (6th Edition):
Othman, R. (2012). Synthesis and characterisation of hybrid carbon-nanotube silica microparticles. (Doctoral Dissertation). University of Manchester. Retrieved from https://www.research.manchester.ac.uk/portal/en/theses/synthesis-and-characterisation-of-hybrid-carbon – nanotube-silica-microparticles(8975f54b-b679-407d-84b0-99d4d67e6efd).html ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.564314
Chicago Manual of Style (16th Edition):
Othman, Raja. “Synthesis and characterisation of hybrid carbon-nanotube silica microparticles.” 2012. Doctoral Dissertation, University of Manchester. Accessed March 04, 2021.
https://www.research.manchester.ac.uk/portal/en/theses/synthesis-and-characterisation-of-hybrid-carbon – nanotube-silica-microparticles(8975f54b-b679-407d-84b0-99d4d67e6efd).html ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.564314.
MLA Handbook (7th Edition):
Othman, Raja. “Synthesis and characterisation of hybrid carbon-nanotube silica microparticles.” 2012. Web. 04 Mar 2021.
Vancouver:
Othman R. Synthesis and characterisation of hybrid carbon-nanotube silica microparticles. [Internet] [Doctoral dissertation]. University of Manchester; 2012. [cited 2021 Mar 04].
Available from: https://www.research.manchester.ac.uk/portal/en/theses/synthesis-and-characterisation-of-hybrid-carbon – nanotube-silica-microparticles(8975f54b-b679-407d-84b0-99d4d67e6efd).html ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.564314.
Council of Science Editors:
Othman R. Synthesis and characterisation of hybrid carbon-nanotube silica microparticles. [Doctoral Dissertation]. University of Manchester; 2012. Available from: https://www.research.manchester.ac.uk/portal/en/theses/synthesis-and-characterisation-of-hybrid-carbon – nanotube-silica-microparticles(8975f54b-b679-407d-84b0-99d4d67e6efd).html ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.564314
University of Edinburgh
27.
Morgan, Frances Katie.
Formulating an improved in vitro hepatic model for drug development and toxicity testing.
Degree: PhD, 2019, University of Edinburgh
URL: http://hdl.handle.net/1842/35899
► There is a need in the pharmaceutical industry for more informative and functional in vitro human models for drug testing as the currently used animal…
(more)
▼ There is a need in the pharmaceutical industry for more informative and functional in vitro human models for drug testing as the currently used animal models have poor correlation to their human counterparts. The liver is the main organ of metabolism and xenobiotics detoxification. As such, a human hepatic in vitro model with improved metabolic functions similar to primary human hepatocytes (PHHs) could reduce the number of animals needed in pre-clinical testing and enhance the relevance of data obtained for subsequent in vivo testing. Most immortalized hepatic cell lines are derived from carcinomas and do not retain a full range of functional activity in vitro. Here we have compared a novel hepatic cell line (HepaRG™), an intrinsic co-culture of hepatocyte and cholangiocyte-like cells, with the commonly used C3A cell line which is a derivative of HepG2 cells, in terms of metabolic competency. We found that the HepaRG™ cells out-perform C3As in a number of metabolic functions that include phase I and II metabolism as well as CYP activity. This makes the HepaRG™ cell line a strong alternative to PHHs for in vitro pre-clinical drug testing. Next, we considered the platform for in vitro modelling. There are currently many tissue engineering models available with improved cell culture characteristics such as 3D spheroids, microfluidic models or 3D printing. However, these methods are costly and time consuming. We have used nanopatterned culture plates to develop a cheaper and faster platform that will produce an enhanced human hepatic culture capable of sustaining a differentiated state for several weeks. Such a model will also allow for multi-experimentation or repeat dosage and would be a significant step towards reducing small animal in vivo testing and may correlate better to pre-clinical human trials. We have specifically selected a nanopatterned and oxygen plasma treated culture system that has shown promise in differentiating other stem-like cells into organ specific cultures without the use of additional chemicals or hormones. By growing HepaRG™ progenitor (HepaRG-P™ ) cells on these prototype plates, we showed a much earlier differentiation compared with the established HepaRG-P™ cell culture protocols. Improved functionality at this early time point can also be seen in terms of CYP activity and markers of maturation. There is also some evidence to suggest specific zonation of mature HepaRG™s within this model. Finally, a real-time, label-free monitoring of cell culture fitness, that encompasses a quantitative analysis of cell culture during treatment with a pharmacological agent, is desirable. An electrical cell impedance substrate (ECIS) platform that fulfils the above criteria was validated for real-time, non-invasive, monitoring of the HepaRG™ cell culture. Chlorpromazine (CPZ), a model cholestatic drug, was used to assess its effect on the HepaRG™ cells using ECIS. This study also gave us the opportunity for a more in-depth analysis of CPZ-induced cholestasis by not only analysing tight junctions, adhesion…
Subjects/Keywords: nanopattern; ECIS; impedance; HepaRG; C3A
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APA ·
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APA (6th Edition):
Morgan, F. K. (2019). Formulating an improved in vitro hepatic model for drug development and toxicity testing. (Doctoral Dissertation). University of Edinburgh. Retrieved from http://hdl.handle.net/1842/35899
Chicago Manual of Style (16th Edition):
Morgan, Frances Katie. “Formulating an improved in vitro hepatic model for drug development and toxicity testing.” 2019. Doctoral Dissertation, University of Edinburgh. Accessed March 04, 2021.
http://hdl.handle.net/1842/35899.
MLA Handbook (7th Edition):
Morgan, Frances Katie. “Formulating an improved in vitro hepatic model for drug development and toxicity testing.” 2019. Web. 04 Mar 2021.
Vancouver:
Morgan FK. Formulating an improved in vitro hepatic model for drug development and toxicity testing. [Internet] [Doctoral dissertation]. University of Edinburgh; 2019. [cited 2021 Mar 04].
Available from: http://hdl.handle.net/1842/35899.
Council of Science Editors:
Morgan FK. Formulating an improved in vitro hepatic model for drug development and toxicity testing. [Doctoral Dissertation]. University of Edinburgh; 2019. Available from: http://hdl.handle.net/1842/35899
Hong Kong University of Science and Technology
28.
Quattrocchi, Emanuele MAE.
An impedance model of electrochemical systems using the generalized distribution of diffusion timescales.
Degree: 2018, Hong Kong University of Science and Technology
URL: http://repository.ust.hk/ir/Record/1783.1-96007
;
https://doi.org/10.14711/thesis-991012638165003412
;
http://repository.ust.hk/ir/bitstream/1783.1-96007/1/th_redirect.html
► Electrochemical impedance spectroscopy (EIS) is a powerful technique used to characterize the behavior of the electrochemical systems for design and diagnostic purposes. However, it is…
(more)
▼ Electrochemical impedance spectroscopy (EIS) is a powerful technique used to characterize the behavior of the electrochemical systems for design and diagnostic purposes. However, it is not easy to interpret EIS data. Particular attention has been paid to porous electrodes, because they can enhance power and energy density of the electrochemical systems but is difficult to characterize their microstructure. In the last decades, several models have been developed, based on “equivalent circuits,” Poisson-Nernst-Planck (PNP) equations, distribution of relaxation of times (DRT) and recently, distribution of diffusion times (DDT). These models, however, can be applied only to thin film electrodes. In this work, a generalized framework is presented, based on DDT method, adopting Tikhonov regularization, which extends the existing theories, analyzing EIS data for thick electrodes. We apply our model to two cases of batteries i) a Si nanowire Li-ion battery and ii) a Li-ion battery with plastic crystal electrolyte, and show the capability to recover the physical properties of the electrochemical systems such as chemical diffusivity D̃ and ionic conductivities of the phases. Furthermore, we highlight that this framework can be used for other classes of electrochemical systems such as semiconductors, fuel cells, and supercapacitors.
Subjects/Keywords: Impedance spectroscopy
; Electrochemical analysis
; Electrochemistry
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Export
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APA (6th Edition):
Quattrocchi, E. M. (2018). An impedance model of electrochemical systems using the generalized distribution of diffusion timescales. (Thesis). Hong Kong University of Science and Technology. Retrieved from http://repository.ust.hk/ir/Record/1783.1-96007 ; https://doi.org/10.14711/thesis-991012638165003412 ; http://repository.ust.hk/ir/bitstream/1783.1-96007/1/th_redirect.html
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Quattrocchi, Emanuele MAE. “An impedance model of electrochemical systems using the generalized distribution of diffusion timescales.” 2018. Thesis, Hong Kong University of Science and Technology. Accessed March 04, 2021.
http://repository.ust.hk/ir/Record/1783.1-96007 ; https://doi.org/10.14711/thesis-991012638165003412 ; http://repository.ust.hk/ir/bitstream/1783.1-96007/1/th_redirect.html.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Quattrocchi, Emanuele MAE. “An impedance model of electrochemical systems using the generalized distribution of diffusion timescales.” 2018. Web. 04 Mar 2021.
Vancouver:
Quattrocchi EM. An impedance model of electrochemical systems using the generalized distribution of diffusion timescales. [Internet] [Thesis]. Hong Kong University of Science and Technology; 2018. [cited 2021 Mar 04].
Available from: http://repository.ust.hk/ir/Record/1783.1-96007 ; https://doi.org/10.14711/thesis-991012638165003412 ; http://repository.ust.hk/ir/bitstream/1783.1-96007/1/th_redirect.html.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Quattrocchi EM. An impedance model of electrochemical systems using the generalized distribution of diffusion timescales. [Thesis]. Hong Kong University of Science and Technology; 2018. Available from: http://repository.ust.hk/ir/Record/1783.1-96007 ; https://doi.org/10.14711/thesis-991012638165003412 ; http://repository.ust.hk/ir/bitstream/1783.1-96007/1/th_redirect.html
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
University College Cork
29.
Savage, Niall Thomas Patrick.
Development of a novel probe integrated with a micro-structured impedance sensor for the detection of breast cancer.
Degree: 2016, University College Cork
URL: http://hdl.handle.net/10468/3022
► The work described in this thesis focuses on the development of an innovative bioimpedance device for the detection of breast cancer using electrical impedance as…
(more)
▼ The work described in this thesis focuses on the development of an innovative bioimpedance device for the detection of breast cancer using electrical
impedance as the detection method. The ability for clinicians to detect and treat cancerous lesions as early as possible results in improved patient outcomes and can reduce the severity of the treatment the patient has to undergo. Therefore, new technology and devices are continually required to improve the specificity and sensitivity of the accepted detection methods. The gold standard for breast cancer detection is digital x-ray mammography but it has some significant downsides associated with it. The development of an adjunct technology to aid in the detection of breast cancers could represent a significant patient and economic benefit. In this project silicon substrates were pattern with two gold microelectrodes that allowed electrical
impedance measurements to be recorded from intact tissue structures. These probes were tested and characterised using a range of in vitro and ex vivo experiments. The end application of this novel sensor device was in a first-in-human clinical trial. The initial results of this study showed that the silicon
impedance device was capable of differentiating between normal and abnormal (benign and cancerous) breast tissue. The mean separation between the two tissue types 4,340 Ω with p < 0.001. The cancer type and grade at the site of the probe recordings was confirmed histologically and correlated with the electrical
impedance measurements to determine if the different subtypes of cancer could each be differentiated. The results presented in this thesis showed that the novel
impedance device demonstrated excellent electrochemical recording potential; was biocompatible with the growth of cultured cell lines and was capable of differentiating between intact biological tissues. The results outlined in this thesis demonstrate the potential feasibility of using electrical
impedance for the differentiation of biological tissue samples. The novelty of this thesis is in the development of a new method of tissue determination with an application in breast cancer detection.
Advisors/Committee Members: O'Sullivan, Martin J., O'Donnell, Brian, Moore, Eric J..
Subjects/Keywords: Impedance; Probe; Clinical; Breast cancer
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APA ·
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CSE |
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APA (6th Edition):
Savage, N. T. P. (2016). Development of a novel probe integrated with a micro-structured impedance sensor for the detection of breast cancer. (Thesis). University College Cork. Retrieved from http://hdl.handle.net/10468/3022
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Savage, Niall Thomas Patrick. “Development of a novel probe integrated with a micro-structured impedance sensor for the detection of breast cancer.” 2016. Thesis, University College Cork. Accessed March 04, 2021.
http://hdl.handle.net/10468/3022.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Savage, Niall Thomas Patrick. “Development of a novel probe integrated with a micro-structured impedance sensor for the detection of breast cancer.” 2016. Web. 04 Mar 2021.
Vancouver:
Savage NTP. Development of a novel probe integrated with a micro-structured impedance sensor for the detection of breast cancer. [Internet] [Thesis]. University College Cork; 2016. [cited 2021 Mar 04].
Available from: http://hdl.handle.net/10468/3022.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Savage NTP. Development of a novel probe integrated with a micro-structured impedance sensor for the detection of breast cancer. [Thesis]. University College Cork; 2016. Available from: http://hdl.handle.net/10468/3022
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Loughborough University
30.
Cruz-Manzo, Samuel.
Electrochemical mechanisms of the impedance spectrum in polymer electrolyte fuel cells.
Degree: PhD, 2013, Loughborough University
URL: http://hdl.handle.net/2134/12316
► Electrochemical impedance spectroscopy (EIS) is a powerful technique that can be applied in-situ to deconvolute the various loss mechanisms in the polymer electrolyte fuel cell…
(more)
▼ Electrochemical impedance spectroscopy (EIS) is a powerful technique that can be applied in-situ to deconvolute the various loss mechanisms in the polymer electrolyte fuel cell (PEFC) that occur at different rates. The frequency response of a PEFC that results from EIS is in essence characterised by energy dissipating and energy storing elements of the cell. It can be represented by an equivalent circuit that is composed of resistors and capacitors respectively. By understanding the arrangement and magnitude of the electrical components in the equivalent electrical circuit, it is possible to generate a deeper understanding of how and where the electrical energy that is generated due to the redox reaction is being dissipated and retained within the real physical system. Although the use of equivalent circuits is often an adequate approach, some electrochemical processes are not adequately described by electrical components. In which case, it is necessary to adopt a more rigorous approach of describing processes through the use of differential equations to describe the physics of the electrochemical system at the frequency domain. Studies in the literature have attempted to construct mathematical models to describe the impedance response of the cathode catalyst layer (CCL) based on conservation equations describing the electrochemical and diffusion processes. However this has resulted in a complicated mathematical analysis which in turn results in complicated solutions. The resulting equations cannot be easily validated against real-world EIS measurements and only analytical results have been reported. In this thesis a mathematical model to describe the impedance response of the CCL has been developed. This model is derived from fundamental electrochemical theory describing the physics of the CCL. The mathematical treatment is simplified by taking into account some considerations based on the EIS theory. The resulting model can be easily applied to real-world EIS measurements of PEFCs and presents parameters commonly known in the electrochemical area. The scientific contribution of this doctoral thesis is mainly divided in two sections: Modelling and Application. The first step of the modelling section develops an equation describing charge conservation in the CCL and together with Ohm s Law equation accounting for ionic conduction, predicts the impedance response of the CCL at low currents. The second step includes the change of oxygen concentration during the oxygen reduction reaction (ORR) into the equation accounting for CCL low current operation. The study of mass transport in the CCL is very complex; the literature has treated it with simplifications and approximations. The finite diffusion distance for oxygen to reach the reaction sites in the CCL forms a complicated network of multi-phase parallel and serial paths and can change in dimension at different operating conditions (flooding, drying). In the mathematical treatment of this doctoral thesis the finite diffusion distance and surface concentration of…
Subjects/Keywords: 621.31; PEFC; EIS; Impedance model
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APA ·
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Export
to Zotero / EndNote / Reference
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APA (6th Edition):
Cruz-Manzo, S. (2013). Electrochemical mechanisms of the impedance spectrum in polymer electrolyte fuel cells. (Doctoral Dissertation). Loughborough University. Retrieved from http://hdl.handle.net/2134/12316
Chicago Manual of Style (16th Edition):
Cruz-Manzo, Samuel. “Electrochemical mechanisms of the impedance spectrum in polymer electrolyte fuel cells.” 2013. Doctoral Dissertation, Loughborough University. Accessed March 04, 2021.
http://hdl.handle.net/2134/12316.
MLA Handbook (7th Edition):
Cruz-Manzo, Samuel. “Electrochemical mechanisms of the impedance spectrum in polymer electrolyte fuel cells.” 2013. Web. 04 Mar 2021.
Vancouver:
Cruz-Manzo S. Electrochemical mechanisms of the impedance spectrum in polymer electrolyte fuel cells. [Internet] [Doctoral dissertation]. Loughborough University; 2013. [cited 2021 Mar 04].
Available from: http://hdl.handle.net/2134/12316.
Council of Science Editors:
Cruz-Manzo S. Electrochemical mechanisms of the impedance spectrum in polymer electrolyte fuel cells. [Doctoral Dissertation]. Loughborough University; 2013. Available from: http://hdl.handle.net/2134/12316
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