subject:(glutathione)

University of Waterloo

1. Wang, Yiran. Extraction and Concentration of Glutathione from Yeast.

Degree: 2018, University of Waterloo

► Glutathione is a tripeptide present in most mammalian tissue. It has a great variety of significant physiological functions, such as regulating cell growth and division;… (more)

Subjects/Keywords: glutathione

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Wang, Y. (2018). Extraction and Concentration of Glutathione from Yeast. (Thesis). University of Waterloo. Retrieved from http://hdl.handle.net/10012/13831

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Wang, Yiran. “Extraction and Concentration of Glutathione from Yeast.” 2018. Thesis, University of Waterloo. Accessed January 16, 2021. http://hdl.handle.net/10012/13831.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Wang, Yiran. “Extraction and Concentration of Glutathione from Yeast.” 2018. Web. 16 Jan 2021.

Vancouver:

Wang Y. Extraction and Concentration of Glutathione from Yeast. [Internet] [Thesis]. University of Waterloo; 2018. [cited 2021 Jan 16]. Available from: http://hdl.handle.net/10012/13831.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Wang Y. Extraction and Concentration of Glutathione from Yeast. [Thesis]. University of Waterloo; 2018. Available from: http://hdl.handle.net/10012/13831

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Wollongong

2. Smith, Cassandra Lee. Modes of copper toxicity in marine microalgae: an intracellular investigation.

Degree: PhD, 2014, University of Wollongong

URL: 060199 Biochemistry and Cell Biology not elsewhere classified ; https://ro.uow.edu.au/theses/4271

► Toxicity of metals to aquatic organisms is dependent on both external factors, such as exposure concentration and water quality parameters, and intracellular processes including… (more)

Subjects/Keywords: Reduced glutathione Glutathione Metallothionein Phytochelatin

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Smith, C. L. (2014). Modes of copper toxicity in marine microalgae: an intracellular investigation. (Doctoral Dissertation). University of Wollongong. Retrieved from 060199 Biochemistry and Cell Biology not elsewhere classified ; https://ro.uow.edu.au/theses/4271

Chicago Manual of Style (16^th Edition):

Smith, Cassandra Lee. “Modes of copper toxicity in marine microalgae: an intracellular investigation.” 2014. Doctoral Dissertation, University of Wollongong. Accessed January 16, 2021. 060199 Biochemistry and Cell Biology not elsewhere classified ; https://ro.uow.edu.au/theses/4271.

MLA Handbook (7^th Edition):

Smith, Cassandra Lee. “Modes of copper toxicity in marine microalgae: an intracellular investigation.” 2014. Web. 16 Jan 2021.

Vancouver:

Smith CL. Modes of copper toxicity in marine microalgae: an intracellular investigation. [Internet] [Doctoral dissertation]. University of Wollongong; 2014. [cited 2021 Jan 16]. Available from: 060199 Biochemistry and Cell Biology not elsewhere classified ; https://ro.uow.edu.au/theses/4271.

Council of Science Editors:

Smith CL. Modes of copper toxicity in marine microalgae: an intracellular investigation. [Doctoral Dissertation]. University of Wollongong; 2014. Available from: 060199 Biochemistry and Cell Biology not elsewhere classified ; https://ro.uow.edu.au/theses/4271

3. Baddariyah Sohsansa. Effect of phenethyl isothiocyante (PEITC) and betong watercress (Nasturtium officinale) on glutathione S-transferase activity and glutathione levels in rats .

Degree: คณะวิทยาศาสตร์ ภาควิชาเภสัชวิทยา, 2014, Prince of Songkla University

URL: http://kb.psu.ac.th/psukb/handle/2010/9867

Subjects/Keywords: Glutathione

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Sohsansa, B. (2014). Effect of phenethyl isothiocyante (PEITC) and betong watercress (Nasturtium officinale) on glutathione S-transferase activity and glutathione levels in rats . (Thesis). Prince of Songkla University. Retrieved from http://kb.psu.ac.th/psukb/handle/2010/9867

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Sohsansa, Baddariyah. “Effect of phenethyl isothiocyante (PEITC) and betong watercress (Nasturtium officinale) on glutathione S-transferase activity and glutathione levels in rats .” 2014. Thesis, Prince of Songkla University. Accessed January 16, 2021. http://kb.psu.ac.th/psukb/handle/2010/9867.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Sohsansa, Baddariyah. “Effect of phenethyl isothiocyante (PEITC) and betong watercress (Nasturtium officinale) on glutathione S-transferase activity and glutathione levels in rats .” 2014. Web. 16 Jan 2021.

Vancouver:

Sohsansa B. Effect of phenethyl isothiocyante (PEITC) and betong watercress (Nasturtium officinale) on glutathione S-transferase activity and glutathione levels in rats . [Internet] [Thesis]. Prince of Songkla University; 2014. [cited 2021 Jan 16]. Available from: http://kb.psu.ac.th/psukb/handle/2010/9867.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Sohsansa B. Effect of phenethyl isothiocyante (PEITC) and betong watercress (Nasturtium officinale) on glutathione S-transferase activity and glutathione levels in rats . [Thesis]. Prince of Songkla University; 2014. Available from: http://kb.psu.ac.th/psukb/handle/2010/9867

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Oregon State University

4. Siller-Cepeda, Jorge H. The role of glutathione in the development and release of rest on 'Redhaven' peaches.

Degree: PhD, Horticulture, 1991, Oregon State University

URL: http://hdl.handle.net/1957/25780

► A rapid and sensitive HPLC method for quantifying both the reduced and oxidized forms of glutathione simultaneously in woody plant tissues was developed. This method… (more)

▼ A rapid and sensitive HPLC method for quantifying both the reduced and oxidized forms of glutathione simultaneously in woody plant tissues was developed. This method was applicable to a variety of woody plant species and different tissues. Total glutathione content in the bark tissue of seven of the woody plant species tested were lower during active plant growth, and higher in the dormant stage. All tested tissues of peach plants contained glutathione. The highest and lowest content was found in the leaves and roots, respectively. 'Redhaven' peach trees acquired the onset of rest on 1 Oct, before any chilling had been experienced. Maximum rest was reached on 1 Nov after the plants were exposed to 320 CU, and 50% of the buds were broken at 860 CU on 1 Dec. Total budbreak and phytotoxicity induced by hydrogen cyanamide applied to 'Redhaven' peach trees was dependent on concentration and time of application. Phytotoxicity was evident at all application dates, but greatest at the highest concentrations. Plants were more resistant to hydrogen cyanamide at maximum rest. Hydrogen cyanamide induced budbreak was best during the post-rest period. Budbreak and phytotoxicity induced by hydrogen cyanamide applied during the quiescent stage were dependent on posttreatment temperature and concentration. All cyanamide treatments inhibited budbreak at all tested temperatures. The inhibition was greatest at the the lowest temperature and at the highest concentrations. Phytotoxicity was greater at 15C and 35C than at 25C, and increased with increased concentrations. The content of GSH and GSSG in the buds changed with the development of rest. During the early phases of rest, when rest intensity increased, the content of GSH and GSSG decreased (15 Oct) and then increased at maximum rest (1 Nov). Content of GSH continued to increase and peaked on 1 Dec at 860 CU. On 15 Dec when the buds were qxiiescent GSH content decreased. In contrast, contents of GSSG did not drop during cjuiescence and were highest on 15 Dec. GSH content induced by chilling was closely associated with the end of rest. Hydrogen cyanamide treatments caused a rapid decrease of GSH content within 12 hr followed by a large increase 24 hr after application. The changes of GSH induced were inversely proportional to cyanamide concentration. Non-treated plants showed at relatively constant GSH and GSSG content during this period of time. Hydrogen cyanamide treatments increased GSH contents at all application dates. The extent of GSH changes was dependent on the physiological status of the bud and cyanamide concentration. At maximum rest the plants were more resistant to cyanamide and this coincided with the highest induced GSH content as compared to all application dates. Advisors/Committee Members: Fuchigami, Leslie H. (advisor).

Subjects/Keywords: Glutathione

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Siller-Cepeda, J. H. (1991). The role of glutathione in the development and release of rest on 'Redhaven' peaches. (Doctoral Dissertation). Oregon State University. Retrieved from http://hdl.handle.net/1957/25780

Chicago Manual of Style (16^th Edition):

Siller-Cepeda, Jorge H. “The role of glutathione in the development and release of rest on 'Redhaven' peaches.” 1991. Doctoral Dissertation, Oregon State University. Accessed January 16, 2021. http://hdl.handle.net/1957/25780.

MLA Handbook (7^th Edition):

Siller-Cepeda, Jorge H. “The role of glutathione in the development and release of rest on 'Redhaven' peaches.” 1991. Web. 16 Jan 2021.

Vancouver:

Siller-Cepeda JH. The role of glutathione in the development and release of rest on 'Redhaven' peaches. [Internet] [Doctoral dissertation]. Oregon State University; 1991. [cited 2021 Jan 16]. Available from: http://hdl.handle.net/1957/25780.

Council of Science Editors:

Siller-Cepeda JH. The role of glutathione in the development and release of rest on 'Redhaven' peaches. [Doctoral Dissertation]. Oregon State University; 1991. Available from: http://hdl.handle.net/1957/25780

5. Thomas, Nicholas, O. Age-related decrease in resilience against acute redox cycling agents: Critical role of declining GSH-dependent detoxification capacity.

Degree: PhD, 2017, Oregon State University

URL: http://hdl.handle.net/1957/61681

► Over the past century, life expectancy in the United States has dramatically increased leading to an increasingly aging population with people reaching, and spending more… (more)

▼ Over the past century, life expectancy in the United States has dramatically increased leading to an increasingly aging population with people reaching, and spending more years in ‘old age’. While this unprecedented shift in population demographics represents great strides for humanity, it is not without cost. One consequence of longer life is the increased accrual of age-associated diseases and chronic pathophysiological conditions. This is evident in the fact that over 80% of Americans over the age of 65 have at least one chronic medical condition [275]. Thus, lifespan has outpaced ‘healthspan’, or the time of one’s life spent free from disease and disuse syndromes. The work in this dissertation is defined by the investigation of “health assurance” biochemical pathways, the failure of which lead to heightened risk for age-related diseases. In particular, I have focused on why resiliency to oxidative stresses decline significantly with age. This focus has led to a research project that ultimately pinpoints a loss in glutathione-dependent defenses as an underlying aging factor, which could enhance risk for a variety of age-related diseases. Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) is a major transcriptional regulator of numerous anti-oxidant, anti-inflammatory, and metabolic genes. We observed that, paradoxically, Nrf2 protein levels decline in the livers of aged rats despite the inflammatory environment evident in that organ. To examine the cause(s) of this loss, we investigated the age-related changes in Nrf2 protein homeostasis and activation in cultured hepatocytes from young (4–6 months) and old (24–28 months) Fischer 344 rats. While no significant age-dependent change in Nrf2 mRNA levels was observed, Nrf2 protein content was attenuated by ~40% with age (p<0.05 , N=4). Treatment with anethole trithione (A3T), along with bortezomib to inhibit degradation of existing protein, caused Nrf2 to accumulate significantly in cells from young animals (p < 0.05), but not old, indicating a lack of new Nrf2 synthesis. We hypothesized that the loss of Nrf2 protein synthesis with age may partly stem from an age-related increase in microRNA inhibition of Nrf2 translation. miRNA-146a, increases by > 2-fold with age and is predicted to bind Nrf2 mRNA. Transfection of hepatocytes from young rats with a miRNA-146a mimic caused a 55% attenuation of Nrf2 translation that paralleled the age-related loss of Nrf2. Overall, these results provide novel insights for the age-related decline in Nrf2 and identify new targets to maintain Nrf2-dependent detoxification with age. Having established that this major transcriptional regulator is attenuated with age, we next examined what effects this would have on toxicological resilience. Isolated hepatocytes from young and old rats were exposed to increasing concentrations of menadione, a vitamin K derivative and redox cycling agent, an LC50 for each age group was established, and results showed a nearly 2-fold increase in susceptibility to menadione (LC50 for young: 405 μM;… Advisors/Committee Members: Hagen, Tory, M. (advisor), Perez, Viviana, I (committee member).

Subjects/Keywords: Glutathione

…2 1.2 Glutathione… …12 1.2.6 Glutathione and detoxification enzymes… …45 Chapter 3. Glutathione Maintenance Mitigates Age Related Susceptibility to Redox Cycling… …61 3.3.9 Glutathione Analysis… …74 Chapter 4. The Age-Related Loss of Mitochondrial Glutathione Exacerbates Menadione…

10 more images…

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Thomas, Nicholas, O. (2017). Age-related decrease in resilience against acute redox cycling agents: Critical role of declining GSH-dependent detoxification capacity. (Doctoral Dissertation). Oregon State University. Retrieved from http://hdl.handle.net/1957/61681

Chicago Manual of Style (16^th Edition):

Thomas, Nicholas, O. “Age-related decrease in resilience against acute redox cycling agents: Critical role of declining GSH-dependent detoxification capacity.” 2017. Doctoral Dissertation, Oregon State University. Accessed January 16, 2021. http://hdl.handle.net/1957/61681.

MLA Handbook (7^th Edition):

Thomas, Nicholas, O. “Age-related decrease in resilience against acute redox cycling agents: Critical role of declining GSH-dependent detoxification capacity.” 2017. Web. 16 Jan 2021.

Vancouver:

Thomas, Nicholas O. Age-related decrease in resilience against acute redox cycling agents: Critical role of declining GSH-dependent detoxification capacity. [Internet] [Doctoral dissertation]. Oregon State University; 2017. [cited 2021 Jan 16]. Available from: http://hdl.handle.net/1957/61681.

Council of Science Editors:

Thomas, Nicholas O. Age-related decrease in resilience against acute redox cycling agents: Critical role of declining GSH-dependent detoxification capacity. [Doctoral Dissertation]. Oregon State University; 2017. Available from: http://hdl.handle.net/1957/61681

University of Hawaii – Manoa

6. Pang, Xiaosha. HIV-induced redox changes and inflammation in the central nervous system and modulatory factors.

Degree: 2016, University of Hawaii – Manoa

URL: http://hdl.handle.net/10125/100634

►

Ph.D. University of Hawaii at Manoa 2013.

Currently 34 million people live with human immunodeficiency virus (HIV) infection. Although the lifespan of HIV patients has… (more)

▼

Ph.D. University of Hawaii at Manoa 2013.

Currently 34 million people live with human immunodeficiency virus (HIV) infection. Although the lifespan of HIV patients has been prolonged by highly active antiretroviral treatment, the prevalence of HIV-associated neurocognitive disorders (HANDs) is increasing. Oxidative stress and inflammation in the central nervous system (CNS) are major causes of HANDs, and concurrent drug abuse may accelerate the progression of symptoms. This dissertation aims to study HIV-induced changes in antioxidants, oxidative stress, and inflammation in the CNS, assess the effects of concurrent methamphetamine (Meth) exposure, and evaluate the protective effect of dietary supplementation of bamboo Phyllostachys edulis extract (BEX). This study centered on the most abundant antioxidant in the brain-glutathione (GSH). The changes of GSH metabolism and GSH-dependent antioxidant enzymes were measured in cerebrospinal fluid (CSF) of human cohorts with HIV infection and/or uses of Meth, and in the brain tissues of HIV-1 model transgenic rats (HIV-1Tg expressing 7 HIV viral proteins) with or without Meth exposure. HIV infection resulted in elevated gamma-glutamyl transpeptidase (GGT) activity, GSH depletion and a several-fold increase in lipid peroxidation in human CSF. Compared to HIV infection, use of Meth resulted in less severe oxidative stress, which may be partially explained by the upregulation of glutathione peroxidase (GPx) and GSH in the CSF. Meth did not interact with HIV in modulating the redox changes in the CSF. In HIV-1Tg rats, redox and inflammatory changes were observed in the brain in a region-specific manner, with little synergy from Meth exposure. The thalamus was highlighted by its high GSH content and systematic upregulation of GSH biosynthesis and GSH-dependent antioxidant enzymes in the HIV-1Tg rats. On the other hand, neuroinflammation markers, such as glial fibrillary acidic protein (GFAP) and p65, were increased in the hippocampus of the transgenic rats, and such changes were effectively normalized by dietary supplementation of BEX. In summary, this dissertation documents the significance of GSH and GSH-dependent antioxidant enzymes in regulating the redox status of CNS, and the potential anti-neuroinflammatory effects of BEX in the context of HIV infection.

Subjects/Keywords: glutathione (GSH)

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Pang, X. (2016). HIV-induced redox changes and inflammation in the central nervous system and modulatory factors. (Thesis). University of Hawaii – Manoa. Retrieved from http://hdl.handle.net/10125/100634

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Pang, Xiaosha. “HIV-induced redox changes and inflammation in the central nervous system and modulatory factors.” 2016. Thesis, University of Hawaii – Manoa. Accessed January 16, 2021. http://hdl.handle.net/10125/100634.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Pang, Xiaosha. “HIV-induced redox changes and inflammation in the central nervous system and modulatory factors.” 2016. Web. 16 Jan 2021.

Vancouver:

Pang X. HIV-induced redox changes and inflammation in the central nervous system and modulatory factors. [Internet] [Thesis]. University of Hawaii – Manoa; 2016. [cited 2021 Jan 16]. Available from: http://hdl.handle.net/10125/100634.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Pang X. HIV-induced redox changes and inflammation in the central nervous system and modulatory factors. [Thesis]. University of Hawaii – Manoa; 2016. Available from: http://hdl.handle.net/10125/100634

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of North Texas

7. Ingle, Brandall L. The Mechanisms of Human Glutathione Synthetase and Related Non-Enyzmatic Catalysis.

Degree: 2015, University of North Texas

URL: https://digital.library.unt.edu/ark:/67531/metadc801927/

► Human glutathione synthetase (hGS) is a homodimeric enzymes that catalyzes the second step in the biological synthesis of glutathione, a critical cellular antioxidant. The enzyme… (more)

▼ Human glutathione synthetase (hGS) is a homodimeric enzymes that catalyzes the second step in the biological synthesis of glutathione, a critical cellular antioxidant. The enzyme exhibits negative cooperativity towards the γ-glutamylcysteine (γ-GC) substrate. In this type of allosteric regulation, the binding of γ-GC at one active site significantly reduces substrate affinity at a second active site over 40 Å away. The presented work explores protein-protein interactions, substrate binding, and allosteric communication through investigation of three regions of hGS: the dimer interface, the S-loop, and the E-loop. Strong electrostatic interactions across the dimer interface of hGS maintain the appropriate tertiary and quaternary enzymatic structure needed for activity. The S-loop and E-loop of hGS form walls of the active site near γ-GC, with some residues serving to bind and position the negatively cooperative substrate. These strong interactions in the active site serve as a trigger for allosteric communication, which then passes through hydrophobic interactions at the interface. A comprehensive computational and experimental approach relates hGS structure with activity and regulation. ATP-grasp enzymes, including hGS, utilize ATP in the nucleophilic attack of a carboxylic acid in a reaction thought to proceed through the formation of an acylphosphate intermediate. Small metal cations are known to chelate the terminal phosphates of actives site ATP, yet the role of these atoms remains unclear. In the presented work, a computational metal substitution study establishes the role these divalent cations in the catalysis of peptide bonds. The simple model is used to determine the impact of metal cations on the thermodynamics and kinetics, an important stepping stone in understanding the importance of metal cations in larger biological systems. Advisors/Committee Members: Cundari, Thomas R., Omary, Mohammad A., Petros, Robby A., Richmond, Michael G., Anderson, Mary E..

Subjects/Keywords: allostery; glutathione; enzyme; catalysis; Glutathione.; Ligases.; Catalysis.

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Ingle, B. L. (2015). The Mechanisms of Human Glutathione Synthetase and Related Non-Enyzmatic Catalysis. (Thesis). University of North Texas. Retrieved from https://digital.library.unt.edu/ark:/67531/metadc801927/

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Ingle, Brandall L. “The Mechanisms of Human Glutathione Synthetase and Related Non-Enyzmatic Catalysis.” 2015. Thesis, University of North Texas. Accessed January 16, 2021. https://digital.library.unt.edu/ark:/67531/metadc801927/.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Ingle, Brandall L. “The Mechanisms of Human Glutathione Synthetase and Related Non-Enyzmatic Catalysis.” 2015. Web. 16 Jan 2021.

Vancouver:

Ingle BL. The Mechanisms of Human Glutathione Synthetase and Related Non-Enyzmatic Catalysis. [Internet] [Thesis]. University of North Texas; 2015. [cited 2021 Jan 16]. Available from: https://digital.library.unt.edu/ark:/67531/metadc801927/.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Ingle BL. The Mechanisms of Human Glutathione Synthetase and Related Non-Enyzmatic Catalysis. [Thesis]. University of North Texas; 2015. Available from: https://digital.library.unt.edu/ark:/67531/metadc801927/

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Mississippi State University

8. Lakdusinghe, Madhubhashini. Thermodynamic studies of Zn2+ binding to glutathione.

Degree: MS, Chemistry, 2015, Mississippi State University

URL: http://sun.library.msstate.edu/ETD-db/theses/available/etd-10302015-124603/ ;

► Glutathione is one of the most abundant organic compounds found in many biological systems. It is a non-protein tripeptide of Glutamic acid, Cysteine and… (more)

Subjects/Keywords: Glutathione; Zinc; Thermodynamic

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Lakdusinghe, M. (2015). Thermodynamic studies of Zn2+ binding to glutathione. (Masters Thesis). Mississippi State University. Retrieved from http://sun.library.msstate.edu/ETD-db/theses/available/etd-10302015-124603/ ;

Chicago Manual of Style (16^th Edition):

Lakdusinghe, Madhubhashini. “Thermodynamic studies of Zn2+ binding to glutathione.” 2015. Masters Thesis, Mississippi State University. Accessed January 16, 2021. http://sun.library.msstate.edu/ETD-db/theses/available/etd-10302015-124603/ ;.

MLA Handbook (7^th Edition):

Lakdusinghe, Madhubhashini. “Thermodynamic studies of Zn2+ binding to glutathione.” 2015. Web. 16 Jan 2021.

Vancouver:

Lakdusinghe M. Thermodynamic studies of Zn2+ binding to glutathione. [Internet] [Masters thesis]. Mississippi State University; 2015. [cited 2021 Jan 16]. Available from: http://sun.library.msstate.edu/ETD-db/theses/available/etd-10302015-124603/ ;.

Council of Science Editors:

Lakdusinghe M. Thermodynamic studies of Zn2+ binding to glutathione. [Masters Thesis]. Mississippi State University; 2015. Available from: http://sun.library.msstate.edu/ETD-db/theses/available/etd-10302015-124603/ ;

University of Georgia

9. Turner, Martha Kathleen. Anthocyanins increase antioxidant enzyme activity in HT-29 adenocarcinoma cells.

Degree: 2014, University of Georgia

URL: http://hdl.handle.net/10724/25966

► Anthocyanins are thought to have antioxidant effects in the body. The effects of two anthocyanins, malvidin and peonidin, on activity of antioxidant enzymes, glutathione-S-transferase (GST),… (more)

Subjects/Keywords: Anthocyanin; Antioxidant; Glutathione peroxidase; Glutathione reductase; Glutathione-S-transferase

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Turner, M. K. (2014). Anthocyanins increase antioxidant enzyme activity in HT-29 adenocarcinoma cells. (Thesis). University of Georgia. Retrieved from http://hdl.handle.net/10724/25966

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Turner, Martha Kathleen. “Anthocyanins increase antioxidant enzyme activity in HT-29 adenocarcinoma cells.” 2014. Thesis, University of Georgia. Accessed January 16, 2021. http://hdl.handle.net/10724/25966.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Turner, Martha Kathleen. “Anthocyanins increase antioxidant enzyme activity in HT-29 adenocarcinoma cells.” 2014. Web. 16 Jan 2021.

Vancouver:

Turner MK. Anthocyanins increase antioxidant enzyme activity in HT-29 adenocarcinoma cells. [Internet] [Thesis]. University of Georgia; 2014. [cited 2021 Jan 16]. Available from: http://hdl.handle.net/10724/25966.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Turner MK. Anthocyanins increase antioxidant enzyme activity in HT-29 adenocarcinoma cells. [Thesis]. University of Georgia; 2014. Available from: http://hdl.handle.net/10724/25966

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Georgia

10. Galambos, Alexis Rose. The effects of blueberry anthocyanidins on antioxidant enzyme activity in human HepG2 cells.

Degree: 2014, University of Georgia

URL: http://hdl.handle.net/10724/28270

► Anthocyanins are thought to have antioxidant effects in the body. The effects of two anthocyanidins, malvidin and delphinidin, on the activities of antioxidant enzymes, glutathione… (more)

Subjects/Keywords: Anthocyanin; Antioxidant; Oxidative Stress; Glutathione Reductase; Glutathione Peroxidase; Glutathione S-Transferase

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Galambos, A. R. (2014). The effects of blueberry anthocyanidins on antioxidant enzyme activity in human HepG2 cells. (Thesis). University of Georgia. Retrieved from http://hdl.handle.net/10724/28270

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Galambos, Alexis Rose. “The effects of blueberry anthocyanidins on antioxidant enzyme activity in human HepG2 cells.” 2014. Thesis, University of Georgia. Accessed January 16, 2021. http://hdl.handle.net/10724/28270.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Galambos, Alexis Rose. “The effects of blueberry anthocyanidins on antioxidant enzyme activity in human HepG2 cells.” 2014. Web. 16 Jan 2021.

Vancouver:

Galambos AR. The effects of blueberry anthocyanidins on antioxidant enzyme activity in human HepG2 cells. [Internet] [Thesis]. University of Georgia; 2014. [cited 2021 Jan 16]. Available from: http://hdl.handle.net/10724/28270.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Galambos AR. The effects of blueberry anthocyanidins on antioxidant enzyme activity in human HepG2 cells. [Thesis]. University of Georgia; 2014. Available from: http://hdl.handle.net/10724/28270

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Utah

11. Raftogianis, Rebecca Blanchard. Total parenteral nutrition alters hepatic drug conjugation in rats;.

Degree: PhD, Pharmaceutics & Pharmaceutical Chemistry;, 1995, University of Utah

URL: http://content.lib.utah.edu/cdm/singleitem/collection/etd1/id/1614/rec/1404

► Total parenteral nutrition (TPN) provides complete nutritional support in settings in which patients cannot eat. TPN, typically administered through a central vein as an elemental… (more)

Subjects/Keywords: Prostaglandin; Glutathione

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Raftogianis, R. B. (1995). Total parenteral nutrition alters hepatic drug conjugation in rats;. (Doctoral Dissertation). University of Utah. Retrieved from http://content.lib.utah.edu/cdm/singleitem/collection/etd1/id/1614/rec/1404

Chicago Manual of Style (16^th Edition):

Raftogianis, Rebecca Blanchard. “Total parenteral nutrition alters hepatic drug conjugation in rats;.” 1995. Doctoral Dissertation, University of Utah. Accessed January 16, 2021. http://content.lib.utah.edu/cdm/singleitem/collection/etd1/id/1614/rec/1404.

MLA Handbook (7^th Edition):

Raftogianis, Rebecca Blanchard. “Total parenteral nutrition alters hepatic drug conjugation in rats;.” 1995. Web. 16 Jan 2021.

Vancouver:

Raftogianis RB. Total parenteral nutrition alters hepatic drug conjugation in rats;. [Internet] [Doctoral dissertation]. University of Utah; 1995. [cited 2021 Jan 16]. Available from: http://content.lib.utah.edu/cdm/singleitem/collection/etd1/id/1614/rec/1404.

Council of Science Editors:

Raftogianis RB. Total parenteral nutrition alters hepatic drug conjugation in rats;. [Doctoral Dissertation]. University of Utah; 1995. Available from: http://content.lib.utah.edu/cdm/singleitem/collection/etd1/id/1614/rec/1404

University of Utah

12. Phaneuf, Holly Louise. Synthesis and evaluation of novel hepatoprotective L-cysteine prodrugs;.

Degree: PhD, Biochemistry;, 1997, University of Utah

URL: http://content.lib.utah.edu/cdm/singleitem/collection/etd1/id/1638/rec/1318

► Numerous deleterious physiological effects result from cellular depletion of glutathione (GSH). GSH is abundant in living systems and exerts several protective functions. Reduction of the… (more)

▼ Numerous deleterious physiological effects result from cellular depletion of glutathione (GSH). GSH is abundant in living systems and exerts several protective functions. Reduction of the normally high levels of GSH in cells results from a wide array of endogenous and exogenous factors. The liver is frequently vulnerable to GSH depletion by exposure to toxins. Developing novel agents that increase GSH in the liver has been the primary goal of this work. Since GSH cannot be taken up by cells and is quickly catabolized, prodrug forms of its constituent L-cysteine, which supports the biosynthesis of GSH, have proved a successful therapeutic alternative. Prodrug versions of L-cysteine are required to overcome the toxicity of L-cystelne itself. Drug targeting as a means of directing agents to particular cells or organs is well established in the case of hepatocyte targeting. The hepatic asialoglycoprotein receptor (ASGPR) recognizes molecules bearing galactose moieties, which is followed by cellular uptake. Three L-cysteine prodrugs possessing galactose were synthesized using the condensation of L-cysteine with aldoses to form a thiazolidine carboxylic acid (TCA). TCAs dissociate nonenzymatically over time and have previously demonstrated GSH-maintaining ability. The galactose-bearing prodrugs were developed with the aim of increasing liver L-cysteine prodrug through ASGPR targeting. Two related glucose-bearing prodrugs were synthesized as controls. Prodrug toxicity was not seen in mice and apparent in cells only at high concentrations after prolonged exposures. Biodistribution of prodrugs in mice and protection using hepatocytes with and without the ASGPR were used to indicate targeting. Protection studies used acetaminophen (APAP), which is well documented as a GSH-depleting hepatotoxin. All five prodrugs protected against APAP, yet prodrug targeting is ambiguous. Additional protection mechanisms involving Phase II enzyme induction were addressed, because thiol induction has been documented. Prodrugs did not cause induction at the doses given, with the possible exception of one, but this was complicated by APAP induction. Studies determining liver and kidney GSH imply that the most conspicuous protection mechanism is the prevention of GSH depletion by APAP. Although ASGPR targeting is not immediately obvious from these studies, the principal goal, the development of novel hepatoprotective GSH-maintaining agents, was achieved.

Subjects/Keywords: Physiological; Glutathione

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Phaneuf, H. L. (1997). Synthesis and evaluation of novel hepatoprotective L-cysteine prodrugs;. (Doctoral Dissertation). University of Utah. Retrieved from http://content.lib.utah.edu/cdm/singleitem/collection/etd1/id/1638/rec/1318

Chicago Manual of Style (16^th Edition):

Phaneuf, Holly Louise. “Synthesis and evaluation of novel hepatoprotective L-cysteine prodrugs;.” 1997. Doctoral Dissertation, University of Utah. Accessed January 16, 2021. http://content.lib.utah.edu/cdm/singleitem/collection/etd1/id/1638/rec/1318.

MLA Handbook (7^th Edition):

Phaneuf, Holly Louise. “Synthesis and evaluation of novel hepatoprotective L-cysteine prodrugs;.” 1997. Web. 16 Jan 2021.

Vancouver:

Phaneuf HL. Synthesis and evaluation of novel hepatoprotective L-cysteine prodrugs;. [Internet] [Doctoral dissertation]. University of Utah; 1997. [cited 2021 Jan 16]. Available from: http://content.lib.utah.edu/cdm/singleitem/collection/etd1/id/1638/rec/1318.

Council of Science Editors:

Phaneuf HL. Synthesis and evaluation of novel hepatoprotective L-cysteine prodrugs;. [Doctoral Dissertation]. University of Utah; 1997. Available from: http://content.lib.utah.edu/cdm/singleitem/collection/etd1/id/1638/rec/1318

University of Georgia

13. Zhou, Yang. Genetic control of the glutathione redox system throughout the life span.

Degree: 2017, University of Georgia

URL: http://hdl.handle.net/10724/36585

► Glutathione (GSH), a ubiquitous tripeptide molecule, regulates numerous cellular processes. In biological systems, GSH exists either in its reduced or oxidized (GSSG) forms, and the… (more)

Subjects/Keywords: Glutathione; Age; Mice; Genetics; Heritability

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Zhou, Y. (2017). Genetic control of the glutathione redox system throughout the life span. (Thesis). University of Georgia. Retrieved from http://hdl.handle.net/10724/36585

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Zhou, Yang. “Genetic control of the glutathione redox system throughout the life span.” 2017. Thesis, University of Georgia. Accessed January 16, 2021. http://hdl.handle.net/10724/36585.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Zhou, Yang. “Genetic control of the glutathione redox system throughout the life span.” 2017. Web. 16 Jan 2021.

Vancouver:

Zhou Y. Genetic control of the glutathione redox system throughout the life span. [Internet] [Thesis]. University of Georgia; 2017. [cited 2021 Jan 16]. Available from: http://hdl.handle.net/10724/36585.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Zhou Y. Genetic control of the glutathione redox system throughout the life span. [Thesis]. University of Georgia; 2017. Available from: http://hdl.handle.net/10724/36585

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Victoria University of Wellington

14. Pal, Ramavati. Proteomic Analysis of Glutathione Transferases from Lucilia Cuprina.

Degree: 2010, Victoria University of Wellington

URL: http://hdl.handle.net/10063/1541

► The glutathione transferases are a family of multifunctional enzymes involved in detoxification of xenobiotic and endogenous electrophilic compounds. Interest in insect GSTs has primarily focused… (more)

▼ The glutathione transferases are a family of multifunctional enzymes involved in detoxification of xenobiotic and endogenous electrophilic compounds. Interest in insect GSTs has primarily focused on their role in insecticide resistance. The sheep blowfly, Lucilia cuprina is a major economic problem for the sheep meat and wool industries in Australasia and hence this thesis has attempted the study of the Lucilia cuprina GST family, using proteomics, with a view to eventually determining their role in insecticide resistance. Combinations of different affinity matrices (glutathione-Sepharose matrix (GSH) followed by dinitrophenyl-glutathione-Sepharose matrix (DNP-GSH)) and two-dimensional electrophoresis has successfully isolated members from major four insect GST classes: Sigma, Delta, Epsilon and Omega. Drosophila melanogaster has been used as a model insect throughout as a basis for comparison. To characterise Lucilia GSTs, the whole metazoan fragmentation database was used for sequence alignment with Lucilia peptides. This approach is broad and speculative but predicts a possible classification of the GSTs based on % similarity and % identity. This method of characterisation yielded match scores that provided a basis for classification, which must at present be regarded as tentative and in need of confirmation. In D. melanogaster and L. cuprina, GSH affinity-purified extracts showed the presence of only Sigma and Delta GSTs. In D. melanogaster, the DNP-GSH affinity-purified GSTs showed mostly the presence of Epsilon and Omega GSTs whereas in L. cuprina no Omega GSTs were detected. In both species, the migration pattern of Delta GST on 2D PAGE gel indicated possible post-translational modification. The results from analysis of LC-MS/MS data by the software PEAKS suggested deamidation at asparagine and glutamine residues in a limited number of the matched peptides of Delta GST. GST activity was present in all developmental stages of L. cuprina. The number of isoenzymes and their extent of expression vary as the insect develops. Delta GSTs were present in all developmental stages. The Sigma GST started expressing from the larval stage and was abundantly present in adult stage. The DNP-GSH affinity matrix purified GSTs which have been tentatively classified as Mu-like GSTs were present in egg, larvae and pupae but totally absent in adult stage. The GST families were characterised by proteomics in the main body sections of L. cuprina. Higher GST activity towards 1-chloro-2, 4-dinitrobenzene (CDNB) was found in the thorax (65.2 %) followed by the abdomen (19.6%) and the head (15.2%). The cytosolic GSTs of a resistant strain (PY81) of L. cuprina had significantly higher (2.26- and 2.6- fold) activity than the susceptible strains (NSW and CSIRO) towards CDNB and 2, 3-dichloro, 4-nitrobenzene (DCNB) respectively. The proteomic analysis of DNP-GSH purified extract from susceptible and resistant strains showed quantitatively higher expression of GSTs on 2D PAGE gel of the PY81 strain. The in vitro interaction of purified GSTs… Advisors/Committee Members: Clark, Alan, Teesdale-Spittle, Paul.

Subjects/Keywords: Glutathione; Transferases; Lucilia cuprina; Proteomics

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Pal, R. (2010). Proteomic Analysis of Glutathione Transferases from Lucilia Cuprina. (Doctoral Dissertation). Victoria University of Wellington. Retrieved from http://hdl.handle.net/10063/1541

Chicago Manual of Style (16^th Edition):

Pal, Ramavati. “Proteomic Analysis of Glutathione Transferases from Lucilia Cuprina.” 2010. Doctoral Dissertation, Victoria University of Wellington. Accessed January 16, 2021. http://hdl.handle.net/10063/1541.

MLA Handbook (7^th Edition):

Pal, Ramavati. “Proteomic Analysis of Glutathione Transferases from Lucilia Cuprina.” 2010. Web. 16 Jan 2021.

Vancouver:

Pal R. Proteomic Analysis of Glutathione Transferases from Lucilia Cuprina. [Internet] [Doctoral dissertation]. Victoria University of Wellington; 2010. [cited 2021 Jan 16]. Available from: http://hdl.handle.net/10063/1541.

Council of Science Editors:

Pal R. Proteomic Analysis of Glutathione Transferases from Lucilia Cuprina. [Doctoral Dissertation]. Victoria University of Wellington; 2010. Available from: http://hdl.handle.net/10063/1541

University of Cape Town

15. Thumser, Alfred Ernst Adolf. The glutathione S-transferases : inhibition, activation, binding and kinetics.

Degree: Image, Division of Medical Biochemistry, 1990, University of Cape Town

URL: http://hdl.handle.net/11427/28958

Subjects/Keywords: Glutathione transferases

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Thumser, A. E. A. (1990). The glutathione S-transferases : inhibition, activation, binding and kinetics. (Thesis). University of Cape Town. Retrieved from http://hdl.handle.net/11427/28958

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Thumser, Alfred Ernst Adolf. “The glutathione S-transferases : inhibition, activation, binding and kinetics.” 1990. Thesis, University of Cape Town. Accessed January 16, 2021. http://hdl.handle.net/11427/28958.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Thumser, Alfred Ernst Adolf. “The glutathione S-transferases : inhibition, activation, binding and kinetics.” 1990. Web. 16 Jan 2021.

Vancouver:

Thumser AEA. The glutathione S-transferases : inhibition, activation, binding and kinetics. [Internet] [Thesis]. University of Cape Town; 1990. [cited 2021 Jan 16]. Available from: http://hdl.handle.net/11427/28958.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Thumser AEA. The glutathione S-transferases : inhibition, activation, binding and kinetics. [Thesis]. University of Cape Town; 1990. Available from: http://hdl.handle.net/11427/28958

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Cape Town

16. Sherman, Morris. Clinical and biochemical studies on the gluthathione S-transferases.

Degree: Image, Division of Chemical Pathology, 1982, University of Cape Town

URL: http://hdl.handle.net/11427/27261

► The glutathione S-transferases (ligandins) are a ubiquitous system of xenobiotic metabolising enzymes. In the rat liver they comprise up to 10% of soluble hepatic protein.… (more)

▼ The glutathione S-transferases (ligandins) are a ubiquitous system of xenobiotic metabolising enzymes. In the rat liver they comprise up to 10% of soluble hepatic protein. Studies in the rat suggested that ligandin was an accurate and sensitive marker of hepatocellular necrosis. and of renal tubular necrosis. The first part of this thesis examines the release of ligandin from liver and kidney in human liver and renal disease in an attempt to determine whether the measurement of ligandin is clinically useful. Ligandin was purified from human liver cytosol using a combination of anion exchange chromatography and gel filtration. The purified protein had similar physicochemical characteristics to ligandin purified by others. The protein was used to raise a monospecific antibody. Ligandin was iodinated by the Chloramine-T method. which yielded a labelled protein of high specific activity. A sensitive and specific radioimmunoassay for human ligandin was developed which had a low intra- and interassay variation. The assay was applied to the study of human liver disease. In acute hepatitis ligandin is released from the liver into serum early in the illness. High serum ligandin levels are seen in the first week of acute hepatitis. The rapid return to normal suggests that ligandin may provide an early indication of recovery. In chronic hepatitis ligandin levels correlated significantly with histological severity of disease. whereas SGOT showed no such correlation. Ligandin may be a better index of severity of disease and for treatment than SGOT. Ligandin was released from the kidney in severe renal ischaemia and in acute tubular necrosis, but was not a reliable predictor or indicator of acute tubular necrosis. Part two examines the distribution of GSH-T activity in organs and in hepatocellular carcinoma. Ligandin was shown to be immunologically similar in all tissues studied. Isoelectric focusing of cytosol separated the three groups of GSH-T activity. Considerable variety in the distribution and activity of GSH-T's was shown in different organs from a single donor, and in the same organs from different donors. Anionic transferase activity was shown to contribute a significant proportion of activity in organs other than the liver. and to be the major source of activity in ovary and lung. In hepatocellular carcinoma cationic GSH-T activity was present in amounts varying from near normal to absent. The anionic and neutral GSH-T's were present in amounts similar to that seen in normal liver. Immunohistochemical studies using a peroxidase-antiperoxidase method showed a rough correlation between tumour differentiation and the amount of ligandin in the tumour. Advisors/Committee Members: Kirsch, Ralph E (advisor).

Subjects/Keywords: Glutathione transferases

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Sherman, M. (1982). Clinical and biochemical studies on the gluthathione S-transferases. (Thesis). University of Cape Town. Retrieved from http://hdl.handle.net/11427/27261

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Sherman, Morris. “Clinical and biochemical studies on the gluthathione S-transferases.” 1982. Thesis, University of Cape Town. Accessed January 16, 2021. http://hdl.handle.net/11427/27261.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Sherman, Morris. “Clinical and biochemical studies on the gluthathione S-transferases.” 1982. Web. 16 Jan 2021.

Vancouver:

Sherman M. Clinical and biochemical studies on the gluthathione S-transferases. [Internet] [Thesis]. University of Cape Town; 1982. [cited 2021 Jan 16]. Available from: http://hdl.handle.net/11427/27261.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Sherman M. Clinical and biochemical studies on the gluthathione S-transferases. [Thesis]. University of Cape Town; 1982. Available from: http://hdl.handle.net/11427/27261

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Florida

17. Xu, Changjie. The Effects and Mechanisms of Consuming Sulfur-Containing Dietary Supplements on Chronic Inflammation in Adults with Obesity.

Degree: PhD, Nutritional Sciences, 2017, University of Florida

URL: https://ufdc.ufl.edu/UFE0051738

► Obesity is global health issue. In the United States, more than one-third of adults are obese. Obesity induces chronic systemic inflammation and increasing obesity positively… (more)

Subjects/Keywords: garlic – glutathione – inflammation – obesity

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Xu, C. (2017). The Effects and Mechanisms of Consuming Sulfur-Containing Dietary Supplements on Chronic Inflammation in Adults with Obesity. (Doctoral Dissertation). University of Florida. Retrieved from https://ufdc.ufl.edu/UFE0051738

Chicago Manual of Style (16^th Edition):

Xu, Changjie. “The Effects and Mechanisms of Consuming Sulfur-Containing Dietary Supplements on Chronic Inflammation in Adults with Obesity.” 2017. Doctoral Dissertation, University of Florida. Accessed January 16, 2021. https://ufdc.ufl.edu/UFE0051738.

MLA Handbook (7^th Edition):

Xu, Changjie. “The Effects and Mechanisms of Consuming Sulfur-Containing Dietary Supplements on Chronic Inflammation in Adults with Obesity.” 2017. Web. 16 Jan 2021.

Vancouver:

Xu C. The Effects and Mechanisms of Consuming Sulfur-Containing Dietary Supplements on Chronic Inflammation in Adults with Obesity. [Internet] [Doctoral dissertation]. University of Florida; 2017. [cited 2021 Jan 16]. Available from: https://ufdc.ufl.edu/UFE0051738.

Council of Science Editors:

Xu C. The Effects and Mechanisms of Consuming Sulfur-Containing Dietary Supplements on Chronic Inflammation in Adults with Obesity. [Doctoral Dissertation]. University of Florida; 2017. Available from: https://ufdc.ufl.edu/UFE0051738

University of Hong Kong

18. Hong, Yifan. Positive feedback between bismuth uptake and glutathione biosynthesis in human cell and bismuth's impacts on metal metabolism.

Degree: 2013, University of Hong Kong

URL: http://hdl.handle.net/10722/209469

Subjects/Keywords: Bismuth; Glutathione

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Hong, Y. (2013). Positive feedback between bismuth uptake and glutathione biosynthesis in human cell and bismuth's impacts on metal metabolism. (Thesis). University of Hong Kong. Retrieved from http://hdl.handle.net/10722/209469

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Hong, Yifan. “Positive feedback between bismuth uptake and glutathione biosynthesis in human cell and bismuth's impacts on metal metabolism.” 2013. Thesis, University of Hong Kong. Accessed January 16, 2021. http://hdl.handle.net/10722/209469.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Hong, Yifan. “Positive feedback between bismuth uptake and glutathione biosynthesis in human cell and bismuth's impacts on metal metabolism.” 2013. Web. 16 Jan 2021.

Vancouver:

Hong Y. Positive feedback between bismuth uptake and glutathione biosynthesis in human cell and bismuth's impacts on metal metabolism. [Internet] [Thesis]. University of Hong Kong; 2013. [cited 2021 Jan 16]. Available from: http://hdl.handle.net/10722/209469.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Hong Y. Positive feedback between bismuth uptake and glutathione biosynthesis in human cell and bismuth's impacts on metal metabolism. [Thesis]. University of Hong Kong; 2013. Available from: http://hdl.handle.net/10722/209469

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of British Columbia

19. Guo, Ningning. GSH : a new candidate neuropeptide in the CNS.

Degree: MS- MSc, Neuroscience, 1991, University of British Columbia

URL: http://hdl.handle.net/2429/29856

► The physiological significance of glutathione (GSH) in the mammalian central nervous system is still uncertain, although some evidence has indicated that GSH may play an… (more)

Subjects/Keywords: Glutathione; Neuropeptides

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Guo, N. (1991). GSH : a new candidate neuropeptide in the CNS. (Masters Thesis). University of British Columbia. Retrieved from http://hdl.handle.net/2429/29856

Chicago Manual of Style (16^th Edition):

Guo, Ningning. “GSH : a new candidate neuropeptide in the CNS.” 1991. Masters Thesis, University of British Columbia. Accessed January 16, 2021. http://hdl.handle.net/2429/29856.

MLA Handbook (7^th Edition):

Guo, Ningning. “GSH : a new candidate neuropeptide in the CNS.” 1991. Web. 16 Jan 2021.

Vancouver:

Guo N. GSH : a new candidate neuropeptide in the CNS. [Internet] [Masters thesis]. University of British Columbia; 1991. [cited 2021 Jan 16]. Available from: http://hdl.handle.net/2429/29856.

Council of Science Editors:

Guo N. GSH : a new candidate neuropeptide in the CNS. [Masters Thesis]. University of British Columbia; 1991. Available from: http://hdl.handle.net/2429/29856

Youngstown State University

20. Warren, John C., III. Evaluation of the Role of gsp, ygiC, and yjfC Genes in Glutathione Metabolism in Escherichia coli by Gene Disruption.

Degree: MSin Chemistry, Department of Chemistry, 2011, Youngstown State University

URL: http://rave.ohiolink.edu/etdc/view?acc_num=ysu1310473424

► Glutathione metabolism differs amongst humans and bacteria and has the potential to be a good target for antibacterial agents. Within <i>Escherichia coli</i>, glutathione can form… (more)

Subjects/Keywords: Chemistry; Gene disruption; Glutathione; Spermidine

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Warren, John C., I. (2011). Evaluation of the Role of gsp, ygiC, and yjfC Genes in Glutathione Metabolism in Escherichia coli by Gene Disruption. (Masters Thesis). Youngstown State University. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=ysu1310473424

Chicago Manual of Style (16^th Edition):

Warren, John C., III. “Evaluation of the Role of gsp, ygiC, and yjfC Genes in Glutathione Metabolism in Escherichia coli by Gene Disruption.” 2011. Masters Thesis, Youngstown State University. Accessed January 16, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=ysu1310473424.

MLA Handbook (7^th Edition):

Warren, John C., III. “Evaluation of the Role of gsp, ygiC, and yjfC Genes in Glutathione Metabolism in Escherichia coli by Gene Disruption.” 2011. Web. 16 Jan 2021.

Vancouver:

Warren, John C. I. Evaluation of the Role of gsp, ygiC, and yjfC Genes in Glutathione Metabolism in Escherichia coli by Gene Disruption. [Internet] [Masters thesis]. Youngstown State University; 2011. [cited 2021 Jan 16]. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=ysu1310473424.

Council of Science Editors:

Warren, John C. I. Evaluation of the Role of gsp, ygiC, and yjfC Genes in Glutathione Metabolism in Escherichia coli by Gene Disruption. [Masters Thesis]. Youngstown State University; 2011. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=ysu1310473424

Youngstown State University

21. Gadapa, Sirisha. Purification and Characterization of Putative Glutathionylspermidine synthetase, YgiC from Escherichia coli.

Degree: MSin Chemistry, Department of Chemistry, 2011, Youngstown State University

URL: http://rave.ohiolink.edu/etdc/view?acc_num=ysu1311165527

► Glutathione (γ-Glu-Cys-Gly) is a tripeptide-, and a primary thiol found in most organisms. It regulates intracellular thiol levels and maintains redox balance. In <i>Escherichia coli</i>… (more)

Subjects/Keywords: Biochemistry; Chemistry; Glutathione; Glutathionylspermidine

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Gadapa, S. (2011). Purification and Characterization of Putative Glutathionylspermidine synthetase, YgiC from Escherichia coli. (Masters Thesis). Youngstown State University. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=ysu1311165527

Chicago Manual of Style (16^th Edition):

Gadapa, Sirisha. “Purification and Characterization of Putative Glutathionylspermidine synthetase, YgiC from Escherichia coli.” 2011. Masters Thesis, Youngstown State University. Accessed January 16, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=ysu1311165527.

MLA Handbook (7^th Edition):

Gadapa, Sirisha. “Purification and Characterization of Putative Glutathionylspermidine synthetase, YgiC from Escherichia coli.” 2011. Web. 16 Jan 2021.

Vancouver:

Gadapa S. Purification and Characterization of Putative Glutathionylspermidine synthetase, YgiC from Escherichia coli. [Internet] [Masters thesis]. Youngstown State University; 2011. [cited 2021 Jan 16]. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=ysu1311165527.

Council of Science Editors:

Gadapa S. Purification and Characterization of Putative Glutathionylspermidine synthetase, YgiC from Escherichia coli. [Masters Thesis]. Youngstown State University; 2011. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=ysu1311165527

22. Lovejoy, Richard Perry. The occurrence of glutathione in the foliage of horticultural plants, and its relation to the use of sulfur as a fungicide.

Degree: Chemistry, 1934, University of Massachusetts

URL: https://scholarworks.umass.edu/theses/1736

Subjects/Keywords: Glutathione; Sulphur

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Lovejoy, R. P. (1934). The occurrence of glutathione in the foliage of horticultural plants, and its relation to the use of sulfur as a fungicide. (Thesis). University of Massachusetts. Retrieved from https://scholarworks.umass.edu/theses/1736

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Lovejoy, Richard Perry. “The occurrence of glutathione in the foliage of horticultural plants, and its relation to the use of sulfur as a fungicide.” 1934. Thesis, University of Massachusetts. Accessed January 16, 2021. https://scholarworks.umass.edu/theses/1736.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Lovejoy, Richard Perry. “The occurrence of glutathione in the foliage of horticultural plants, and its relation to the use of sulfur as a fungicide.” 1934. Web. 16 Jan 2021.

Vancouver:

Lovejoy RP. The occurrence of glutathione in the foliage of horticultural plants, and its relation to the use of sulfur as a fungicide. [Internet] [Thesis]. University of Massachusetts; 1934. [cited 2021 Jan 16]. Available from: https://scholarworks.umass.edu/theses/1736.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Lovejoy RP. The occurrence of glutathione in the foliage of horticultural plants, and its relation to the use of sulfur as a fungicide. [Thesis]. University of Massachusetts; 1934. Available from: https://scholarworks.umass.edu/theses/1736

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Cape Town

23. Corrigall, Anne Vint. Human glutathione S-transferases : characterization, tissue distribution and kinetic studies.

Degree: Image, UCT/MRC Liver Research Centre, 1988, University of Cape Town

URL: http://hdl.handle.net/11427/27205

► In this study the purification of human basic and near-neutral liver, and human basic and acidic lung glutathione S-transferases (GSH S-T) was undertaken. Purification of… (more)

▼ In this study the purification of human basic and near-neutral liver, and human basic and acidic lung glutathione S-transferases (GSH S-T) was undertaken. Purification of the basic and near-neutral GSH S-T was achieved using a combination of affinity chromatography, chromatofocusing and immunoaffinity chromatography. Affinity and ion exchange chromatography were employed in the purification of the basic and acidic lung forms. The purified proteins had similar physicochemical characteristics to the GSH S-T purified by others. The binding of 1-chloro-2,4-dinitrobenzene (CDNB) to the 3 classes of human GSH S-T, viz. basic, near-neutral and acidic and the effects of such binding, if any, were examined. Human acidic lung GSH S-T is irreversibly inactivated by CDNB in the absence of the co-substrate glutathione (GSH). The time-dependent inactivation is pseudo-first order and demonstrates saturation kinetics, suggesting that inactivation occurs from an EI complex. GSH protects the enzyme against CDNB inactivation. In contrast, the basic and near-neutral GSH S-T are not significantly inactivated by CDNB. Incubation with [¹⁴C]-CDNB indicated covalent binding to all 3 classes of GSH S-T. When the basic and acidic GSH S-T were incubated with [¹⁴C]-CDNB and GSH, cleaved with cyanogen bromide, and chromatographed by HPLC, a single peptide fraction was found to be labelled in both classes. Incubation in the absence of GSH yielded 1 and 2 additional labelled peptide fractions for the basic and acidic transferases, respectively. These results suggest that while CDNB arylates all 3 classes of human GSH S-T, only the acidic GSH S-T possesses a specific GSH-sensitive CDNB binding site, which when occupied leads to time-dependent inactivation of the enzyme. The tissue distribution and localization of the 3 classes of human GSH S-T in normal and tumour tissue was examined. Antibodies to representatives of the 3 classes were raised in rabbits, and radial immunodiffusion employed to quantitate their concentrations in the cytosol of 18 organs from 9 individuals. The data provide the first direct, quantitative evidence for the inter-individual and inter-organ variation suggested by earlier workers. The absence of the near-neutral GSH S-T in 5 of the 9 individuals studied confirms an earlier suggestion of a "null" allele for this transferase. Basic and acidic GSH S-T (apart from in a single liver), were always present. Near-neutral GSH S-T, when present, were found in all tissues examined. The marked inter-organ and inter-individual variation observed in this study may explain individual and organ susceptibility to drugs, toxins and carcinogens. The immunohistochemical localization of the 3 classes of GSH S-T reveals important differences in their localization, and may provide insight into their functions in various organs and tissues. Advisors/Committee Members: Kirsch, Ralph E (advisor).

Subjects/Keywords: Glutathione transferase; Glutathione transferases

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Corrigall, A. V. (1988). Human glutathione S-transferases : characterization, tissue distribution and kinetic studies. (Thesis). University of Cape Town. Retrieved from http://hdl.handle.net/11427/27205

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Corrigall, Anne Vint. “Human glutathione S-transferases : characterization, tissue distribution and kinetic studies.” 1988. Thesis, University of Cape Town. Accessed January 16, 2021. http://hdl.handle.net/11427/27205.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Corrigall, Anne Vint. “Human glutathione S-transferases : characterization, tissue distribution and kinetic studies.” 1988. Web. 16 Jan 2021.

Vancouver:

Corrigall AV. Human glutathione S-transferases : characterization, tissue distribution and kinetic studies. [Internet] [Thesis]. University of Cape Town; 1988. [cited 2021 Jan 16]. Available from: http://hdl.handle.net/11427/27205.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Corrigall AV. Human glutathione S-transferases : characterization, tissue distribution and kinetic studies. [Thesis]. University of Cape Town; 1988. Available from: http://hdl.handle.net/11427/27205

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Georgia

24. Governo, Annette Cairns. The effects of the flavonoids quercetin and genistein on the antioxidant enzymes Cu, Zn superoxide dismutase, glutathione peroxidase, and glutathione reductase in male Sprague-Dawley rats.

Degree: 2014, University of Georgia

URL: http://hdl.handle.net/10724/21838

► Quercetin (QC) and genistein (GS) are phytochemicals found in fruits and vegetables. These compounds may exert protective effects by altering antioxidant enzyme activities. The objective… (more)

Subjects/Keywords: Flavonoids; Quercetin; Genistein; Copper Zinc Superoxide Dismutase; Glutathione Peroxidase; Glutathione Reductase

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Governo, A. C. (2014). The effects of the flavonoids quercetin and genistein on the antioxidant enzymes Cu, Zn superoxide dismutase, glutathione peroxidase, and glutathione reductase in male Sprague-Dawley rats. (Thesis). University of Georgia. Retrieved from http://hdl.handle.net/10724/21838

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Governo, Annette Cairns. “The effects of the flavonoids quercetin and genistein on the antioxidant enzymes Cu, Zn superoxide dismutase, glutathione peroxidase, and glutathione reductase in male Sprague-Dawley rats.” 2014. Thesis, University of Georgia. Accessed January 16, 2021. http://hdl.handle.net/10724/21838.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Governo, Annette Cairns. “The effects of the flavonoids quercetin and genistein on the antioxidant enzymes Cu, Zn superoxide dismutase, glutathione peroxidase, and glutathione reductase in male Sprague-Dawley rats.” 2014. Web. 16 Jan 2021.

Vancouver:

Governo AC. The effects of the flavonoids quercetin and genistein on the antioxidant enzymes Cu, Zn superoxide dismutase, glutathione peroxidase, and glutathione reductase in male Sprague-Dawley rats. [Internet] [Thesis]. University of Georgia; 2014. [cited 2021 Jan 16]. Available from: http://hdl.handle.net/10724/21838.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Governo AC. The effects of the flavonoids quercetin and genistein on the antioxidant enzymes Cu, Zn superoxide dismutase, glutathione peroxidase, and glutathione reductase in male Sprague-Dawley rats. [Thesis]. University of Georgia; 2014. Available from: http://hdl.handle.net/10724/21838

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Cape Town

25. Goold, Richard David. The glutathione S-transferases : kinetics, binding and inhibition.

Degree: Image, Division of Medical Biochemistry & Structural Biology, 1989, University of Cape Town

URL: http://hdl.handle.net/11427/27175

► The glutathione S-transferases are a group of enzymes which catalyse the conjugation of reduced glutathione with a variety of electrophilic molecules, and they are therefore… (more)

Subjects/Keywords: Medical Biochemistry; Glutathione transferase; Glutathione transferases; Glutathione transferases - Analysis

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Goold, R. D. (1989). The glutathione S-transferases : kinetics, binding and inhibition. (Thesis). University of Cape Town. Retrieved from http://hdl.handle.net/11427/27175

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Goold, Richard David. “The glutathione S-transferases : kinetics, binding and inhibition.” 1989. Thesis, University of Cape Town. Accessed January 16, 2021. http://hdl.handle.net/11427/27175.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Goold, Richard David. “The glutathione S-transferases : kinetics, binding and inhibition.” 1989. Web. 16 Jan 2021.

Vancouver:

Goold RD. The glutathione S-transferases : kinetics, binding and inhibition. [Internet] [Thesis]. University of Cape Town; 1989. [cited 2021 Jan 16]. Available from: http://hdl.handle.net/11427/27175.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Goold RD. The glutathione S-transferases : kinetics, binding and inhibition. [Thesis]. University of Cape Town; 1989. Available from: http://hdl.handle.net/11427/27175

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

NSYSU

26. Jiang, Jhih-yu. Lysozyme-directed synthesis of platinum nanoclusters as a mimic oxidase for sensing glutathione.

Degree: Master, Chemistry, 2013, NSYSU

URL: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0622113-231202

► We present a simple, one-pot approach for synthesizing ultrafine platinum (Pt) nanocluster (NCs) under alkaline conditions using lysozyme (Lys) as a template. Pt NC formation… (more)

Subjects/Keywords: Lysozyme; mimic oxidase; glutathione; platinum nanoclusters

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Jiang, J. (2013). Lysozyme-directed synthesis of platinum nanoclusters as a mimic oxidase for sensing glutathione. (Thesis). NSYSU. Retrieved from http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0622113-231202

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Jiang, Jhih-yu. “Lysozyme-directed synthesis of platinum nanoclusters as a mimic oxidase for sensing glutathione.” 2013. Thesis, NSYSU. Accessed January 16, 2021. http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0622113-231202.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Jiang, Jhih-yu. “Lysozyme-directed synthesis of platinum nanoclusters as a mimic oxidase for sensing glutathione.” 2013. Web. 16 Jan 2021.

Vancouver:

Jiang J. Lysozyme-directed synthesis of platinum nanoclusters as a mimic oxidase for sensing glutathione. [Internet] [Thesis]. NSYSU; 2013. [cited 2021 Jan 16]. Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0622113-231202.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Jiang J. Lysozyme-directed synthesis of platinum nanoclusters as a mimic oxidase for sensing glutathione. [Thesis]. NSYSU; 2013. Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0622113-231202

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Otago

27. Miller, Jody Carolyn. Selenium supplementation for high risk coronary artery disease patients .

Degree: 2011, University of Otago

URL: http://hdl.handle.net/10523/1906

► Low activities of glutathione peroxidase 1 (GPx1), a selenium-dependent antioxidant enzyme, have been associated with increased risk of cardiac events in patients with coronary artery… (more)

▼ Low activities of glutathione peroxidase 1 (GPx1), a selenium-dependent antioxidant enzyme, have been associated with increased risk of cardiac events in patients with coronary artery disease. In addition, genetic variants in the gene encoding for GPx1 have been associated with lower enzyme activity and these genotypes have been linked to an increased risk of coronary artery disease. The aim of the research presented in this thesis was to investigate the effect of increasing GPx1 activity on risk of recurrent cardiac events and biomarkers of inflammation and oxidative stress in high-risk coronary artery disease patients. Furthermore, we wished to investigate the influence of genetic variants in the GPx1 gene on GPx activity. The low selenium environment in New Zealand makes this an ideal setting for investigating the relation between selenium, GPx1 and coronary artery disease. The effect of increasing GPx1 activity on the risk of recurrent cardiac events was examined in a 2-year, randomised, placebo controlled clinical trial (RCT) involving 148 coronary artery disease patients recruited from the cardiac surgery waiting list. Participants received a daily supplement containing 100 μg of selenium, as L-selenomethionine (SeMet) or a placebo. Plasma selenium concentrations, whole blood glutathione peroxidase (GPx) activity, high sensitivity C-reactive protein (CRP), and biomarkers of oxidative stress were measured at baseline and 12 weeks after enrolment into the study. Whole blood GPx activities in the selenium group at week 12 were 14% (6 U/g Hb) higher than the placebo group (P<0.001), however, no differences in the 2-year rates of clinical cardiac events were noted (HR 0.99, 95%CI 0.50, 1.95). In addition, selenium supplementation did not alter any biomarker of oxidative stress or inflammation. Percutaneous coronary intervention is associated with increased inflammation, which plays a crucial role in the pathogenesis of restenosis. We investigated whether selenium supplementation reduced plasma markers of inflammation in a 12-week, RCT involving 136 percutaneous coronary intervention patients. Participants received a daily supplement containing 100 μg of SeMet or placebo. Plasma selenium, whole blood GPx activity, CRP, soluble vascular adhesion molecule-1, soluble intercellular adhesion molecule-1, paraoxanase-1, and blood lipids were measured at baseline and at week 12. GPx activity was higher in the selenium group, by 16% (P<0.001), yet there were no significant differences between the selenium and placebo groups in any of the plasma markers of inflammation. To determine if inherited genotypes in two single nucleotide polymorphism of GPx1 modified the effect of selenium supplementation on GPx1 activity, 277 patients from the above studies were genotyped for a single nucleotide polymorphism at codon 198 (Pro198Leu) and a sub-group (n=105) were genotyped for the polyalanine repeat sequence in exon 1 (Ala5, Ala6 or Ala7) of the GPx1 gene. Mean whole blood GPx activity in the selenium group was 14% higher… Advisors/Committee Members: Thomson, Christine (advisor).

Subjects/Keywords: selenium; coronary artery disease; glutathione peroxidase

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Miller, J. C. (2011). Selenium supplementation for high risk coronary artery disease patients . (Doctoral Dissertation). University of Otago. Retrieved from http://hdl.handle.net/10523/1906

Chicago Manual of Style (16^th Edition):

Miller, Jody Carolyn. “Selenium supplementation for high risk coronary artery disease patients .” 2011. Doctoral Dissertation, University of Otago. Accessed January 16, 2021. http://hdl.handle.net/10523/1906.

MLA Handbook (7^th Edition):

Miller, Jody Carolyn. “Selenium supplementation for high risk coronary artery disease patients .” 2011. Web. 16 Jan 2021.

Vancouver:

Miller JC. Selenium supplementation for high risk coronary artery disease patients . [Internet] [Doctoral dissertation]. University of Otago; 2011. [cited 2021 Jan 16]. Available from: http://hdl.handle.net/10523/1906.

Council of Science Editors:

Miller JC. Selenium supplementation for high risk coronary artery disease patients . [Doctoral Dissertation]. University of Otago; 2011. Available from: http://hdl.handle.net/10523/1906

University of Pretoria

28. [No author]. Protection of recombinant glutathione reductase by Oryzacystatin-I in transgenic tobacco .

Degree: 2013, University of Pretoria

URL: http://upetd.up.ac.za/thesis/available/etd-05142013-135140/

► Protein degradation poses a significant challenge for the efficient production of recombinant proteins in plants, affecting the stability and yield of the recombinant protein. In… (more)

Subjects/Keywords: Glutathione reductase (gr); Transgenic tobacco plants; UCTD

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

author], [. (2013). Protection of recombinant glutathione reductase by Oryzacystatin-I in transgenic tobacco . (Masters Thesis). University of Pretoria. Retrieved from http://upetd.up.ac.za/thesis/available/etd-05142013-135140/

Chicago Manual of Style (16^th Edition):

author], [No. “Protection of recombinant glutathione reductase by Oryzacystatin-I in transgenic tobacco .” 2013. Masters Thesis, University of Pretoria. Accessed January 16, 2021. http://upetd.up.ac.za/thesis/available/etd-05142013-135140/.

MLA Handbook (7^th Edition):

author], [No. “Protection of recombinant glutathione reductase by Oryzacystatin-I in transgenic tobacco .” 2013. Web. 16 Jan 2021.

Vancouver:

author] [. Protection of recombinant glutathione reductase by Oryzacystatin-I in transgenic tobacco . [Internet] [Masters thesis]. University of Pretoria; 2013. [cited 2021 Jan 16]. Available from: http://upetd.up.ac.za/thesis/available/etd-05142013-135140/.

Council of Science Editors:

author] [. Protection of recombinant glutathione reductase by Oryzacystatin-I in transgenic tobacco . [Masters Thesis]. University of Pretoria; 2013. Available from: http://upetd.up.ac.za/thesis/available/etd-05142013-135140/

29. Bueno, Aline [UNESP]. Papel do sistema antioxidante e influência do gênero na capacidade de desenvolvimento de embriões iniciais em diferentes modelos de diabete experimental.

Degree: 2016, Universidade Estadual Paulista

URL: http://hdl.handle.net/11449/144544

►

Early embryos recovered from diabetic rats show increased number of blastomeres undergoing apoptosis and decreased total number of blastomeres, suggesting impaired litter size and newborn… (more)

▼

Early embryos recovered from diabetic rats show increased number of blastomeres undergoing apoptosis and decreased total number of blastomeres, suggesting impaired litter size and newborn weight. This might increase the chances of metabolic disorders in adulthood of these animals. Since diabetes-induced hyperglycemia impairs the redox balance, the aim was to evaluate the embryonic oxidative stress status before the implantation in order to identify whether there are differences in levels of oxidative stress in early embryos from diabetic dams. Thus, we hypothesized the decreased cell number found in early embryos recovered from diabetic rats is due to the low embryonic ability to maintain their own redox balance. Our study shows that rats with streptozotocin-induced mild and severe diabetes present impaired redox status in early pregnancy. This maternal unbalance directly influences the embryonic redox status, reflecting the increased reactive oxygen species in the morula stage. We also showed that regardless of hyperglycemic level the embryos trigger defense mechanisms involved in the excessive free radical scavenging as an attempt to survive. Nevertheless, the success of this defense mechanism seems to depend on maternal hyperglycemia, highlighting the importance of the programmed pregnancy as well as appropriate medical care starting in early stages of human diabetic pregnancy.

Embriões iniciais recuperados de ratas diabéticos apresentam aumento do número de blastômeros em apoptose e diminuição do número total de blastômeros, além de prejuízo no tamanho da ninhada peso fetal. Isto pode aumentar as chances de desordens metabólicas na idade adulta destes animais. A hiperglicemia induzida por diabetes prejudica o equilíbrio redox, o objetivo deste trabalho foi avaliar o estado de estresse oxidativo embrionário antes da implantação, a fim de identificar se há diferenças nos níveis de estresse oxidativo em embriões iniciais de ratas diabéticos. Assim, temos a hipótese de que a redução no número de células encontrada em embriões precoces recuperados a partir de ratas diabéticas se deve à baixa capacidade embrionária de manter o seu próprio equilíbrio redox. Nosso estudo mostra que os ratos com diabetes moderado e grave apresentam o estado redox prejudicado no início da prenhez diabética. Este desequilíbrio materno influencia diretamente o estado redox embrionário, refletindo o aumento das espécies reativas de oxigênio na fase de mórula. Nós também mostramos que, independentemente do nível hiperglicêmico os embriões acionam mecanismos de defesa envolvidos na eliminação de radicais livres excessiva como uma tentativa de sobreviver. No entanto, o sucesso deste mecanismo de defesa parece depender da hiperglicemia materna, destacando a importância da gravidez programada, bem como cuidados médicos apropriados começando nos estágios iniciais da gravidez diabética humana

Advisors/Committee Members: Damasceno, Débora Cristina [UNESP], Perecin, Felipe [UNESP], Universidade Estadual Paulista (UNESP).

Subjects/Keywords: Glutathione; Morula; Free radicals; Hyperglycemia; Rats

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Bueno, A. [. (2016). Papel do sistema antioxidante e influência do gênero na capacidade de desenvolvimento de embriões iniciais em diferentes modelos de diabete experimental. (Thesis). Universidade Estadual Paulista. Retrieved from http://hdl.handle.net/11449/144544

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Bueno, Aline [UNESP]. “Papel do sistema antioxidante e influência do gênero na capacidade de desenvolvimento de embriões iniciais em diferentes modelos de diabete experimental.” 2016. Thesis, Universidade Estadual Paulista. Accessed January 16, 2021. http://hdl.handle.net/11449/144544.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Bueno, Aline [UNESP]. “Papel do sistema antioxidante e influência do gênero na capacidade de desenvolvimento de embriões iniciais em diferentes modelos de diabete experimental.” 2016. Web. 16 Jan 2021.

Vancouver:

Bueno A[. Papel do sistema antioxidante e influência do gênero na capacidade de desenvolvimento de embriões iniciais em diferentes modelos de diabete experimental. [Internet] [Thesis]. Universidade Estadual Paulista; 2016. [cited 2021 Jan 16]. Available from: http://hdl.handle.net/11449/144544.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Bueno A[. Papel do sistema antioxidante e influência do gênero na capacidade de desenvolvimento de embriões iniciais em diferentes modelos de diabete experimental. [Thesis]. Universidade Estadual Paulista; 2016. Available from: http://hdl.handle.net/11449/144544

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Alberta

30. Turkistani, Abdullah A. REGULATION OF FOXO TRANSCRIPTION FACTORS BY OXIDATIVE STRESS: ROLE OF GLUTATHIONE.

Degree: MS, Faculty of Pharmacy and Pharmaceutical Sciences, 2013, University of Alberta

URL: https://era.library.ualberta.ca/files/x346d526m

► FoxO transcription factors are downstream mediators of insulin effects that can bind to DNA and regulate transcription of multiple target genes. These target genes are… (more)

Subjects/Keywords: FoxO; Buthionine Sulfoximine; Diethyl Maleate; Glutathione

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Turkistani, A. A. (2013). REGULATION OF FOXO TRANSCRIPTION FACTORS BY OXIDATIVE STRESS: ROLE OF GLUTATHIONE. (Masters Thesis). University of Alberta. Retrieved from https://era.library.ualberta.ca/files/x346d526m

Chicago Manual of Style (16^th Edition):

Turkistani, Abdullah A. “REGULATION OF FOXO TRANSCRIPTION FACTORS BY OXIDATIVE STRESS: ROLE OF GLUTATHIONE.” 2013. Masters Thesis, University of Alberta. Accessed January 16, 2021. https://era.library.ualberta.ca/files/x346d526m.

MLA Handbook (7^th Edition):

Turkistani, Abdullah A. “REGULATION OF FOXO TRANSCRIPTION FACTORS BY OXIDATIVE STRESS: ROLE OF GLUTATHIONE.” 2013. Web. 16 Jan 2021.

Vancouver:

Turkistani AA. REGULATION OF FOXO TRANSCRIPTION FACTORS BY OXIDATIVE STRESS: ROLE OF GLUTATHIONE. [Internet] [Masters thesis]. University of Alberta; 2013. [cited 2021 Jan 16]. Available from: https://era.library.ualberta.ca/files/x346d526m.

Council of Science Editors:

Turkistani AA. REGULATION OF FOXO TRANSCRIPTION FACTORS BY OXIDATIVE STRESS: ROLE OF GLUTATHIONE. [Masters Thesis]. University of Alberta; 2013. Available from: https://era.library.ualberta.ca/files/x346d526m

		in
And / Or
		in
And / Or
		in
And / Or
		in

Open Access Theses and Dissertations