Advanced search options

Advanced Search Options 🞨

Browse by author name (“Author name starts with…”).

Find ETDs with:

in
/  
in
/  
in
/  
in

Written in Published in Earliest date Latest date

Sorted by

Results per page:

Sorted by: relevance · author · university · dateNew search

You searched for subject:(gas emboli). Showing records 1 – 2 of 2 total matches.

Search Limiters

Last 2 Years | English Only

No search limiters apply to these results.

▼ Search Limiters


University of Adelaide

1. Harding, Joanne Elizabeth. An examination into the origins of microscopic gas emboli in blast.

Degree: 2015, University of Adelaide

Injuries from blast are found in a variety of clinical settings following exposure to an explosion. An explosion results in a blast wave, formed as it releases (and expands) the gas produced, into the immediate surrounding environment. While blast trauma is well documented in the literature, the origins of microscopic gas emboli resulting from blast are not. As such the management of gas emboli for blast victims is currently not based upon research evidence. The major objective of this research was to outline and test an alternative theory to microscopic gas emboli development in blast other than the popular and untested translocation theory. This research has shown a rapid decompression effect liberates a dissolved gas (carbon dioxide) from blood to gas bubble, this was supported by a lowered carbon dioxide content in active samples and aligned acid-base chemistry using a blood gas analyser. These findings justified a further experiment using an explosives experiment, again using blood samples and blood gas analysis. Although the blast experiment did not provide clear evidence in support of the autologous theory for microscopic gas emboli formation (due to the effects of the positive pressure phase), it justifies the continuation of the search for mechanisms of emboli development other than translocation because the bubbling in blood could not possibly have resulted from translocation via damaged pulmonary architecture. Advisors/Committee Members: Henneberg, Maciej (advisor), School of Medicine (school).

Subjects/Keywords: explosives trauma; gas emboli; negative pressure; phase of blast

Record DetailsSimilar RecordsGoogle PlusoneFacebookTwitterCiteULikeMendeleyreddit

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Harding, J. E. (2015). An examination into the origins of microscopic gas emboli in blast. (Thesis). University of Adelaide. Retrieved from http://hdl.handle.net/2440/96825

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Harding, Joanne Elizabeth. “An examination into the origins of microscopic gas emboli in blast.” 2015. Thesis, University of Adelaide. Accessed September 15, 2019. http://hdl.handle.net/2440/96825.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Harding, Joanne Elizabeth. “An examination into the origins of microscopic gas emboli in blast.” 2015. Web. 15 Sep 2019.

Vancouver:

Harding JE. An examination into the origins of microscopic gas emboli in blast. [Internet] [Thesis]. University of Adelaide; 2015. [cited 2019 Sep 15]. Available from: http://hdl.handle.net/2440/96825.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Harding JE. An examination into the origins of microscopic gas emboli in blast. [Thesis]. University of Adelaide; 2015. Available from: http://hdl.handle.net/2440/96825

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

2. Loddé, Brice. Etude de la variation de la capacité de diffusion pulmonaire du monoxyde de carbone (DLCO) sur les riques d'accident de décompression : Study of the decreases of diffusing lung capacity of carbon monoxide on decompression sickness risks.

Degree: Docteur es, Physiologie, physiophatologie, biologie systémique médicale, 2018, Brest

L’exposition hyperbare induit des risques sanitaires, en particulier d’accidents de décompression (ADD), dont la probabilité dépend de multiples facteurs, tant externes qu’individuels. Parmi ceux-ci, l’altération de la barrière alvéolo-capillaire est peu ou pas étudiée. Nous avons donc cherché à identifier les effets d’une altération pulmonaire caractérisée par une diminution de la capacité de diffusion alvéolo-capillaire du monoxyde de carbone (DLCO) sur le risque d’ADD. Après un bilan d’aptitude préalable, chaque volontaire a été évalué avant et après la plongée.15 plongeurs professionnels civils répartis en 2 groupes en fonction de leur DLCO, normale (Contrôle) ou diminuée (DLCO), ont réalisé une plongée standardisée à 20 mètres pendant 40 minutes dans le bassin d’eau de mer d’IFREMER. Nous avons mesuré le score de bulles intravasculaires (VGE), la réponse microcirculatoire par débitmétrie laser doppler et les concentrations de différents paramètres biologiques en particulier l’aldostéronémie. Même en l’absence de survenue d’ADD, tous les plongeurs produisent des VGE. Le groupe DLCO est caractérisé par un pic de VGE plus tardif (60 minutes vs 30 minutes) et une tendance à des scores plus importants (Grade IV : 17% vs 11%). Par ailleurs, l’hypoaldostéronémie n’est observée que dans le groupe contrôle (-30.4±24.6%), pas dans le groupe DLCO (+14.8±34.7%). En dehors d’une diminution du risque thrombotique chez tous les plongeurs, les autres paramètres mesurés sont inchangés. Ces résultats évoquent une augmentation du risque d’ADD devant être confirmée par d’autres études.

Hyperbaric exposure leads to a risk of decompression sickness (DCS). The likelihood of DCS depends on multiple factors, external as well as individual. Among them, the alteration of the blood-air barrier has been poorly studied.Therefore, we measured the effect of pulmonary impairment characterized by a decreased diffusing lung capacity of carbon monoxide (DLCO) on the risk of DCS.15 professional divers were splited into 2 groups according to their DLCO, normal (control) or decreased (DLCO), and enrolled after an initial full “fit-to-dive” clinical check-up. They made a standardized 20 meters/40 minutes SCUBA dive in a sea water pool (IFREMER) Vascular Gas Emboli (VGE) score, micro-circulatory response, inflammatory biomarkers, thrombotic factors, and aldosteron rate were measured pre- and post-dive. Although no DCS occurred, all the divers showed VGE after diving. Compared to the control group, we observed in the DLCO group an increased latency to the VGE peak (60 vs 30 minutes) and a tendency for higher VGE scores (Grade IV: 17% vs 11%). A significant decrease (-30.4±24.6%) of aldosteron rate was observed in control and not in the DLCO group (+14.8±34.7%). Most of the biological parameters and microvascular response remained unchanged while all divers had a lowered post-dive thrombotic risk.These results imply that divers with a decreased DLCO might be exposed to an increased DCS risk.Further studies are required to confirm the implication and…

Advisors/Committee Members: Guerrero, François (thesis director), Lafère, Pierre (thesis director).

Subjects/Keywords: Plongée sous-marine; Embole vasculaire gazeux; Aldostérone; Exposition professionnelle; SCUBA diving; Vascular gas emboli; Aldosteron; Occupational exposure; 612

Record DetailsSimilar RecordsGoogle PlusoneFacebookTwitterCiteULikeMendeleyreddit

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Loddé, B. (2018). Etude de la variation de la capacité de diffusion pulmonaire du monoxyde de carbone (DLCO) sur les riques d'accident de décompression : Study of the decreases of diffusing lung capacity of carbon monoxide on decompression sickness risks. (Doctoral Dissertation). Brest. Retrieved from http://www.theses.fr/2018BRES0097

Chicago Manual of Style (16th Edition):

Loddé, Brice. “Etude de la variation de la capacité de diffusion pulmonaire du monoxyde de carbone (DLCO) sur les riques d'accident de décompression : Study of the decreases of diffusing lung capacity of carbon monoxide on decompression sickness risks.” 2018. Doctoral Dissertation, Brest. Accessed September 15, 2019. http://www.theses.fr/2018BRES0097.

MLA Handbook (7th Edition):

Loddé, Brice. “Etude de la variation de la capacité de diffusion pulmonaire du monoxyde de carbone (DLCO) sur les riques d'accident de décompression : Study of the decreases of diffusing lung capacity of carbon monoxide on decompression sickness risks.” 2018. Web. 15 Sep 2019.

Vancouver:

Loddé B. Etude de la variation de la capacité de diffusion pulmonaire du monoxyde de carbone (DLCO) sur les riques d'accident de décompression : Study of the decreases of diffusing lung capacity of carbon monoxide on decompression sickness risks. [Internet] [Doctoral dissertation]. Brest; 2018. [cited 2019 Sep 15]. Available from: http://www.theses.fr/2018BRES0097.

Council of Science Editors:

Loddé B. Etude de la variation de la capacité de diffusion pulmonaire du monoxyde de carbone (DLCO) sur les riques d'accident de décompression : Study of the decreases of diffusing lung capacity of carbon monoxide on decompression sickness risks. [Doctoral Dissertation]. Brest; 2018. Available from: http://www.theses.fr/2018BRES0097

.