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You searched for subject:(functional selectivity). Showing records 1 – 18 of 18 total matches.

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Vanderbilt University

1. Yin, Shen. Allosteric modulation of metabotropic glutamate receptors.

Degree: PhD, Pharmacology, 2013, Vanderbilt University

 Metabotropic glutamate receptors (mGlus) are a group of Family C Seven Transmembrane Spanning Receptors that play important roles in modulating signaling transduction, particularly within the… (more)

Subjects/Keywords: heterodimerization; functional selectivity; pharmacology; allosteric modulators; mGlu

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APA (6th Edition):

Yin, S. (2013). Allosteric modulation of metabotropic glutamate receptors. (Doctoral Dissertation). Vanderbilt University. Retrieved from http://etd.library.vanderbilt.edu//available/etd-11262013-230503/ ;

Chicago Manual of Style (16th Edition):

Yin, Shen. “Allosteric modulation of metabotropic glutamate receptors.” 2013. Doctoral Dissertation, Vanderbilt University. Accessed December 08, 2019. http://etd.library.vanderbilt.edu//available/etd-11262013-230503/ ;.

MLA Handbook (7th Edition):

Yin, Shen. “Allosteric modulation of metabotropic glutamate receptors.” 2013. Web. 08 Dec 2019.

Vancouver:

Yin S. Allosteric modulation of metabotropic glutamate receptors. [Internet] [Doctoral dissertation]. Vanderbilt University; 2013. [cited 2019 Dec 08]. Available from: http://etd.library.vanderbilt.edu//available/etd-11262013-230503/ ;.

Council of Science Editors:

Yin S. Allosteric modulation of metabotropic glutamate receptors. [Doctoral Dissertation]. Vanderbilt University; 2013. Available from: http://etd.library.vanderbilt.edu//available/etd-11262013-230503/ ;


University of Kansas

2. Johnson, Stephanie. Design and Synthesis of Functionally Selective Kappa Opioid Receptor Ligands.

Degree: MS, Medicinal Chemistry, 2017, University of Kansas

 The ability of ligands to differentially regulate the activity of signaling pathways coupled to a receptor potentially enables researchers to optimize therapeutically relevant efficacies, while… (more)

Subjects/Keywords: Pharmaceutical sciences; Organic chemistry; Chemistry; functional; kappa; opioid; selectivity; U50; 488

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APA (6th Edition):

Johnson, S. (2017). Design and Synthesis of Functionally Selective Kappa Opioid Receptor Ligands. (Masters Thesis). University of Kansas. Retrieved from http://hdl.handle.net/1808/26154

Chicago Manual of Style (16th Edition):

Johnson, Stephanie. “Design and Synthesis of Functionally Selective Kappa Opioid Receptor Ligands.” 2017. Masters Thesis, University of Kansas. Accessed December 08, 2019. http://hdl.handle.net/1808/26154.

MLA Handbook (7th Edition):

Johnson, Stephanie. “Design and Synthesis of Functionally Selective Kappa Opioid Receptor Ligands.” 2017. Web. 08 Dec 2019.

Vancouver:

Johnson S. Design and Synthesis of Functionally Selective Kappa Opioid Receptor Ligands. [Internet] [Masters thesis]. University of Kansas; 2017. [cited 2019 Dec 08]. Available from: http://hdl.handle.net/1808/26154.

Council of Science Editors:

Johnson S. Design and Synthesis of Functionally Selective Kappa Opioid Receptor Ligands. [Masters Thesis]. University of Kansas; 2017. Available from: http://hdl.handle.net/1808/26154


The Ohio State University

3. Schmid, Cullen L. Differential regulation of serotonin 2A receptor responsiveness by agonist-directed interactions with beta-arrestin2.

Degree: PhD, Neuroscience Graduate Studies Program, 2011, The Ohio State University

 The G protein-coupled, serotonin 2A (5-HT2A) receptor is a major drug target for the treatment of a number of mental health disorders, including schizophrenia, anxiety… (more)

Subjects/Keywords: Neurosciences; Pharmacology; G protein-coupled receptor; Serotonin 2A receptor; beta-arrestin2; hallucinogens; functional selectivity

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APA (6th Edition):

Schmid, C. L. (2011). Differential regulation of serotonin 2A receptor responsiveness by agonist-directed interactions with beta-arrestin2. (Doctoral Dissertation). The Ohio State University. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=osu1300287547

Chicago Manual of Style (16th Edition):

Schmid, Cullen L. “Differential regulation of serotonin 2A receptor responsiveness by agonist-directed interactions with beta-arrestin2.” 2011. Doctoral Dissertation, The Ohio State University. Accessed December 08, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=osu1300287547.

MLA Handbook (7th Edition):

Schmid, Cullen L. “Differential regulation of serotonin 2A receptor responsiveness by agonist-directed interactions with beta-arrestin2.” 2011. Web. 08 Dec 2019.

Vancouver:

Schmid CL. Differential regulation of serotonin 2A receptor responsiveness by agonist-directed interactions with beta-arrestin2. [Internet] [Doctoral dissertation]. The Ohio State University; 2011. [cited 2019 Dec 08]. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=osu1300287547.

Council of Science Editors:

Schmid CL. Differential regulation of serotonin 2A receptor responsiveness by agonist-directed interactions with beta-arrestin2. [Doctoral Dissertation]. The Ohio State University; 2011. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=osu1300287547


UCLA

4. Yu, Peiyuan. Computational Studies on the Reactivity, Selectivity and Molecular Dynamics of Cycloaddition Reactions.

Degree: Chemistry, 2017, UCLA

 The first part of this dissertation describes computational studies of higher-order cycloadditions with a focus on elucidating the origins of periselectivity. These reactions involve ambimodal… (more)

Subjects/Keywords: Chemistry; Organic chemistry; Cycloaddition; Density Functional Theory; Diels–Alder; Molecular Dynamics; Reactivity; Selectivity

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APA (6th Edition):

Yu, P. (2017). Computational Studies on the Reactivity, Selectivity and Molecular Dynamics of Cycloaddition Reactions. (Thesis). UCLA. Retrieved from http://www.escholarship.org/uc/item/1jk894mq

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Yu, Peiyuan. “Computational Studies on the Reactivity, Selectivity and Molecular Dynamics of Cycloaddition Reactions.” 2017. Thesis, UCLA. Accessed December 08, 2019. http://www.escholarship.org/uc/item/1jk894mq.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Yu, Peiyuan. “Computational Studies on the Reactivity, Selectivity and Molecular Dynamics of Cycloaddition Reactions.” 2017. Web. 08 Dec 2019.

Vancouver:

Yu P. Computational Studies on the Reactivity, Selectivity and Molecular Dynamics of Cycloaddition Reactions. [Internet] [Thesis]. UCLA; 2017. [cited 2019 Dec 08]. Available from: http://www.escholarship.org/uc/item/1jk894mq.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Yu P. Computational Studies on the Reactivity, Selectivity and Molecular Dynamics of Cycloaddition Reactions. [Thesis]. UCLA; 2017. Available from: http://www.escholarship.org/uc/item/1jk894mq

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation


University of Arizona

5. Olson, Keith Mathew. Atypical Opioid Interactions – Development of Selective Mu-Delta Heterodimer Antagonists, Clinical Opioids at Non-Mu Pain Targets and Endogenous Biased Signaling .

Degree: 2017, University of Arizona

 Most clinical opioids produce analgesia through the Mu Opioid Receptor (MOR) providing the only effective treatment for chronic pain patients. These studies explore three pre-clinical… (more)

Subjects/Keywords: Bivalent; Delta Opioid Receptor; Functional Selectivity; MDOR Heterodimer; Mu Opioid Receptor; Opioid Signaling

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APA (6th Edition):

Olson, K. M. (2017). Atypical Opioid Interactions – Development of Selective Mu-Delta Heterodimer Antagonists, Clinical Opioids at Non-Mu Pain Targets and Endogenous Biased Signaling . (Doctoral Dissertation). University of Arizona. Retrieved from http://hdl.handle.net/10150/626669

Chicago Manual of Style (16th Edition):

Olson, Keith Mathew. “Atypical Opioid Interactions – Development of Selective Mu-Delta Heterodimer Antagonists, Clinical Opioids at Non-Mu Pain Targets and Endogenous Biased Signaling .” 2017. Doctoral Dissertation, University of Arizona. Accessed December 08, 2019. http://hdl.handle.net/10150/626669.

MLA Handbook (7th Edition):

Olson, Keith Mathew. “Atypical Opioid Interactions – Development of Selective Mu-Delta Heterodimer Antagonists, Clinical Opioids at Non-Mu Pain Targets and Endogenous Biased Signaling .” 2017. Web. 08 Dec 2019.

Vancouver:

Olson KM. Atypical Opioid Interactions – Development of Selective Mu-Delta Heterodimer Antagonists, Clinical Opioids at Non-Mu Pain Targets and Endogenous Biased Signaling . [Internet] [Doctoral dissertation]. University of Arizona; 2017. [cited 2019 Dec 08]. Available from: http://hdl.handle.net/10150/626669.

Council of Science Editors:

Olson KM. Atypical Opioid Interactions – Development of Selective Mu-Delta Heterodimer Antagonists, Clinical Opioids at Non-Mu Pain Targets and Endogenous Biased Signaling . [Doctoral Dissertation]. University of Arizona; 2017. Available from: http://hdl.handle.net/10150/626669


University of Guelph

6. Silenieks, Leonardo. The Effect of 5-HT2C Receptor Activation on Nausea-Induced Behaviour in Rats .

Degree: 2014, University of Guelph

 The present study aimed at investigating the role of the 5-HT2C receptor in nausea using different models of nausea-induced behaviour in rats. Two chemically distinct… (more)

Subjects/Keywords: Neuroscience; Nausea; Serotonin; 5-HT2C; Lorcaserin; CP-809101; Pharmacology; Behavioural Neuroscience; Obesity; Conditioned Gaping; Taste Reactivity; Functional Selectivity

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APA (6th Edition):

Silenieks, L. (2014). The Effect of 5-HT2C Receptor Activation on Nausea-Induced Behaviour in Rats . (Thesis). University of Guelph. Retrieved from https://atrium.lib.uoguelph.ca/xmlui/handle/10214/8306

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Silenieks, Leonardo. “The Effect of 5-HT2C Receptor Activation on Nausea-Induced Behaviour in Rats .” 2014. Thesis, University of Guelph. Accessed December 08, 2019. https://atrium.lib.uoguelph.ca/xmlui/handle/10214/8306.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Silenieks, Leonardo. “The Effect of 5-HT2C Receptor Activation on Nausea-Induced Behaviour in Rats .” 2014. Web. 08 Dec 2019.

Vancouver:

Silenieks L. The Effect of 5-HT2C Receptor Activation on Nausea-Induced Behaviour in Rats . [Internet] [Thesis]. University of Guelph; 2014. [cited 2019 Dec 08]. Available from: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/8306.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Silenieks L. The Effect of 5-HT2C Receptor Activation on Nausea-Induced Behaviour in Rats . [Thesis]. University of Guelph; 2014. Available from: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/8306

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation


Université de Montréal

7. Trottier, Giacomo. The biasing of the 5-HT4 receptor as an antidepressant target .

Degree: 2017, Université de Montréal

 La dépression majeure peut être très dommageable pour le 8% des Nord-Américains qui en souffriront au moins une fois durant leur vie. Les traitements actuels… (more)

Subjects/Keywords: 5-HT; RS67333; BRET; AD; Antidepressant; pCREB; CREB; Anhedonia; Zacopride; Prucalopride; ML10302; 5-HT4; Functional Selectivity; anhédonie; GPCR; récepteur 5-HT4; 5-HT4 Receptor; Sélectivité Fonctionnelle

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APA (6th Edition):

Trottier, G. (2017). The biasing of the 5-HT4 receptor as an antidepressant target . (Thesis). Université de Montréal. Retrieved from http://hdl.handle.net/1866/18903

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Trottier, Giacomo. “The biasing of the 5-HT4 receptor as an antidepressant target .” 2017. Thesis, Université de Montréal. Accessed December 08, 2019. http://hdl.handle.net/1866/18903.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Trottier, Giacomo. “The biasing of the 5-HT4 receptor as an antidepressant target .” 2017. Web. 08 Dec 2019.

Vancouver:

Trottier G. The biasing of the 5-HT4 receptor as an antidepressant target . [Internet] [Thesis]. Université de Montréal; 2017. [cited 2019 Dec 08]. Available from: http://hdl.handle.net/1866/18903.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Trottier G. The biasing of the 5-HT4 receptor as an antidepressant target . [Thesis]. Université de Montréal; 2017. Available from: http://hdl.handle.net/1866/18903

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

8. Nattino, Francesco. Ab initio molecular dynamics calculations on reactions of molecules with metal surfaces.

Degree: 2015, Theoretical Chemistry Group, Leiden Institute of Chemistry (LIC), Faculty of Science, Leiden University

 Reactions on metal surfaces are of scientific interest due to the tremendous relevance of heterogeneous catalysis. Single crystal surfaces under controlled physical conditions are generally… (more)

Subjects/Keywords: Ab-initio-molecular-dynamics; Density-functional-theory; Gas-surface dynamics; Surface-temperature effects; Mode specificity; Bond selectivity; Ab-initio-molecular-dynamics; Density-functional-theory; Gas-surface dynamics; Surface-temperature effects; Mode specificity; Bond selectivity

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APA (6th Edition):

Nattino, F. (2015). Ab initio molecular dynamics calculations on reactions of molecules with metal surfaces. (Doctoral Dissertation). Theoretical Chemistry Group, Leiden Institute of Chemistry (LIC), Faculty of Science, Leiden University. Retrieved from http://hdl.handle.net/1887/35980

Chicago Manual of Style (16th Edition):

Nattino, Francesco. “Ab initio molecular dynamics calculations on reactions of molecules with metal surfaces.” 2015. Doctoral Dissertation, Theoretical Chemistry Group, Leiden Institute of Chemistry (LIC), Faculty of Science, Leiden University. Accessed December 08, 2019. http://hdl.handle.net/1887/35980.

MLA Handbook (7th Edition):

Nattino, Francesco. “Ab initio molecular dynamics calculations on reactions of molecules with metal surfaces.” 2015. Web. 08 Dec 2019.

Vancouver:

Nattino F. Ab initio molecular dynamics calculations on reactions of molecules with metal surfaces. [Internet] [Doctoral dissertation]. Theoretical Chemistry Group, Leiden Institute of Chemistry (LIC), Faculty of Science, Leiden University; 2015. [cited 2019 Dec 08]. Available from: http://hdl.handle.net/1887/35980.

Council of Science Editors:

Nattino F. Ab initio molecular dynamics calculations on reactions of molecules with metal surfaces. [Doctoral Dissertation]. Theoretical Chemistry Group, Leiden Institute of Chemistry (LIC), Faculty of Science, Leiden University; 2015. Available from: http://hdl.handle.net/1887/35980

9. Stallaert, Wayne. Use of cellular impedance to characterize ligand functional selectivity at G protein-coupled receptors .

Degree: 2014, Université de Montréal

 Les récepteurs couplés aux protéines G (RCPGs) représentent la plus grande famille de cibles thérapeutiques pour le traitement d’une panoplie de pathologies humaines. Bien que… (more)

Subjects/Keywords: Récepteurs couplés aux protéines G; Récepteur β2-adrénergique; Sélectivité fonctionnelle des ligands; Réseaux signalétique; Impédance cellulaire; Cardiomyocytes; Découverte de médicaments; G protein-coupled receptors; β2-adrenergic receptor; Ligand functional selectivity; Signalling networks; Cellular impedance

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APA (6th Edition):

Stallaert, W. (2014). Use of cellular impedance to characterize ligand functional selectivity at G protein-coupled receptors . (Thesis). Université de Montréal. Retrieved from http://hdl.handle.net/1866/11055

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Stallaert, Wayne. “Use of cellular impedance to characterize ligand functional selectivity at G protein-coupled receptors .” 2014. Thesis, Université de Montréal. Accessed December 08, 2019. http://hdl.handle.net/1866/11055.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Stallaert, Wayne. “Use of cellular impedance to characterize ligand functional selectivity at G protein-coupled receptors .” 2014. Web. 08 Dec 2019.

Vancouver:

Stallaert W. Use of cellular impedance to characterize ligand functional selectivity at G protein-coupled receptors . [Internet] [Thesis]. Université de Montréal; 2014. [cited 2019 Dec 08]. Available from: http://hdl.handle.net/1866/11055.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Stallaert W. Use of cellular impedance to characterize ligand functional selectivity at G protein-coupled receptors . [Thesis]. Université de Montréal; 2014. Available from: http://hdl.handle.net/1866/11055

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation


Georgia Tech

10. Pak, Richard. An investigation of perceptual load, aging, and the functional field of view.

Degree: PhD, Psychology, 2005, Georgia Tech

 A common metaphor for visual attention is the spotlight (Posner, 1980). It follows from the spotlight metaphor and other similar models (e.g., zoom-lens model; Eriksen… (more)

Subjects/Keywords: Perceptual load; FFOV; Aging; Functional field of view; Selectivity (Psychology); Visual perception; Aging; Attention

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APA (6th Edition):

Pak, R. (2005). An investigation of perceptual load, aging, and the functional field of view. (Doctoral Dissertation). Georgia Tech. Retrieved from http://hdl.handle.net/1853/7585

Chicago Manual of Style (16th Edition):

Pak, Richard. “An investigation of perceptual load, aging, and the functional field of view.” 2005. Doctoral Dissertation, Georgia Tech. Accessed December 08, 2019. http://hdl.handle.net/1853/7585.

MLA Handbook (7th Edition):

Pak, Richard. “An investigation of perceptual load, aging, and the functional field of view.” 2005. Web. 08 Dec 2019.

Vancouver:

Pak R. An investigation of perceptual load, aging, and the functional field of view. [Internet] [Doctoral dissertation]. Georgia Tech; 2005. [cited 2019 Dec 08]. Available from: http://hdl.handle.net/1853/7585.

Council of Science Editors:

Pak R. An investigation of perceptual load, aging, and the functional field of view. [Doctoral Dissertation]. Georgia Tech; 2005. Available from: http://hdl.handle.net/1853/7585

11. Gabl, Michael. Modulation of Receptor Signaling and Functional Selectivity in Neutrophils.

Degree: 2017, University of Gothenburg / Göteborgs Universitet

 Neutrophils are important effector cells of the innate immune system and in the regulation of inflammation. Many of their functions, such as chemotactic migration, secretion… (more)

Subjects/Keywords: neutrophils; G-protein coupled receptors; reactive oxygen species; ligands; functional selectivity; allosteric modulation

…56 Functional Selectivity… …certain morphological and functional changes and they are transferred from a resting to a primed… …TLR11 is a non-functional pseudogene and TLR12 and 13 are lacking [80]. Human… 

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APA (6th Edition):

Gabl, M. (2017). Modulation of Receptor Signaling and Functional Selectivity in Neutrophils. (Thesis). University of Gothenburg / Göteborgs Universitet. Retrieved from http://hdl.handle.net/2077/52860

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Gabl, Michael. “Modulation of Receptor Signaling and Functional Selectivity in Neutrophils.” 2017. Thesis, University of Gothenburg / Göteborgs Universitet. Accessed December 08, 2019. http://hdl.handle.net/2077/52860.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Gabl, Michael. “Modulation of Receptor Signaling and Functional Selectivity in Neutrophils.” 2017. Web. 08 Dec 2019.

Vancouver:

Gabl M. Modulation of Receptor Signaling and Functional Selectivity in Neutrophils. [Internet] [Thesis]. University of Gothenburg / Göteborgs Universitet; 2017. [cited 2019 Dec 08]. Available from: http://hdl.handle.net/2077/52860.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Gabl M. Modulation of Receptor Signaling and Functional Selectivity in Neutrophils. [Thesis]. University of Gothenburg / Göteborgs Universitet; 2017. Available from: http://hdl.handle.net/2077/52860

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

12. Martí Solano, Maria. Ligand selectivity at GPCRs: from multitarget binding profiles to biased agonism.

Degree: Departament de Ciències Experimentals i de la Salut, 2015, Universitat Pompeu Fabra

 Deeper characterization of drugs targeting G protein-coupled receptors (GPCR)s has shown that their mechanisms of action can be more complex than previously thought. On the… (more)

Subjects/Keywords: GPCR; Afinitat d’unió; Selectivitat funcional; Serotonina; Farmacoinformàtica; Binding affinity; Functional selectivity; Serotonin; Pharmacoinformatics; 615

…pathway or functional selectivity and analyze its potential impact in different therapeutic… …functional selectivity at the 2A serotonin receptor, an important antipsychotic drug target… …receptors: implications for functional selectivity 173 xv 3.5 Detection of new biased agonists… …with wanted and unwanted effects. 4 1.3 Functional selectivity and its therapeutic… …different type of selectivity, namely functional selectivity. Functional selectivity is a property… 

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APA (6th Edition):

Martí Solano, M. (2015). Ligand selectivity at GPCRs: from multitarget binding profiles to biased agonism. (Thesis). Universitat Pompeu Fabra. Retrieved from http://hdl.handle.net/10803/285964

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Martí Solano, Maria. “Ligand selectivity at GPCRs: from multitarget binding profiles to biased agonism.” 2015. Thesis, Universitat Pompeu Fabra. Accessed December 08, 2019. http://hdl.handle.net/10803/285964.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Martí Solano, Maria. “Ligand selectivity at GPCRs: from multitarget binding profiles to biased agonism.” 2015. Web. 08 Dec 2019.

Vancouver:

Martí Solano M. Ligand selectivity at GPCRs: from multitarget binding profiles to biased agonism. [Internet] [Thesis]. Universitat Pompeu Fabra; 2015. [cited 2019 Dec 08]. Available from: http://hdl.handle.net/10803/285964.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Martí Solano M. Ligand selectivity at GPCRs: from multitarget binding profiles to biased agonism. [Thesis]. Universitat Pompeu Fabra; 2015. Available from: http://hdl.handle.net/10803/285964

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation


University of California – San Francisco

13. Chang, Wei Chun. Controlling the Agonist-Mediated and Constitutive G-Protein Signaling of the Human 5-HT4 Receptor.

Degree: Pharmaceutical Sciences and Pharmacogenomics, 2007, University of California – San Francisco

 G-protein-coupled receptors (GPCRs) signal through a limited number of G-protein pathways and are crucial in many biological processes. The molecular and functional diversity of GPCRs… (more)

Subjects/Keywords: Biology, Cell; GPCR; RASSL; 5HT4; domain swapping; chimera; G protein signaling; agonist mediated; constitutive signaling; functional selectivity

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APA (6th Edition):

Chang, W. C. (2007). Controlling the Agonist-Mediated and Constitutive G-Protein Signaling of the Human 5-HT4 Receptor. (Thesis). University of California – San Francisco. Retrieved from http://www.escholarship.org/uc/item/6hf4j89w

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Chang, Wei Chun. “Controlling the Agonist-Mediated and Constitutive G-Protein Signaling of the Human 5-HT4 Receptor.” 2007. Thesis, University of California – San Francisco. Accessed December 08, 2019. http://www.escholarship.org/uc/item/6hf4j89w.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Chang, Wei Chun. “Controlling the Agonist-Mediated and Constitutive G-Protein Signaling of the Human 5-HT4 Receptor.” 2007. Web. 08 Dec 2019.

Vancouver:

Chang WC. Controlling the Agonist-Mediated and Constitutive G-Protein Signaling of the Human 5-HT4 Receptor. [Internet] [Thesis]. University of California – San Francisco; 2007. [cited 2019 Dec 08]. Available from: http://www.escholarship.org/uc/item/6hf4j89w.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Chang WC. Controlling the Agonist-Mediated and Constitutive G-Protein Signaling of the Human 5-HT4 Receptor. [Thesis]. University of California – San Francisco; 2007. Available from: http://www.escholarship.org/uc/item/6hf4j89w

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

14. Janevski, G. Alex. Causes and Consequences of Extinction and Survival in Fossil Marine Invertebrates with a Special Focus on the Crinoidea (Phylum Echinodermata).

Degree: PhD, Geology, 2011, University of Michigan

 In the geologic past, certain traits increased the chance of survival of some marine invertebrate taxa, which means that extinction did not occur randomly. However,… (more)

Subjects/Keywords: Extinction Selectivity; Phylogeny; Crinoids; Marine Invertebrates; Biomechanics; Functional Morphology; Geology and Earth Sciences; Science

…Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . Functional morphology of swimming… …selectivity increases . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Observed extinction… …the contribution of regional selectivity to observed extinction selectivity patterns… …ix 19 36 53 91 91 104 LIST OF APPENDICES Appendix A. Evidence for selectivity for… …the P-Tr extinction event? Did extinction selectivity affect crinoids during this event? The… 

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APA (6th Edition):

Janevski, G. A. (2011). Causes and Consequences of Extinction and Survival in Fossil Marine Invertebrates with a Special Focus on the Crinoidea (Phylum Echinodermata). (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/84527

Chicago Manual of Style (16th Edition):

Janevski, G Alex. “Causes and Consequences of Extinction and Survival in Fossil Marine Invertebrates with a Special Focus on the Crinoidea (Phylum Echinodermata).” 2011. Doctoral Dissertation, University of Michigan. Accessed December 08, 2019. http://hdl.handle.net/2027.42/84527.

MLA Handbook (7th Edition):

Janevski, G Alex. “Causes and Consequences of Extinction and Survival in Fossil Marine Invertebrates with a Special Focus on the Crinoidea (Phylum Echinodermata).” 2011. Web. 08 Dec 2019.

Vancouver:

Janevski GA. Causes and Consequences of Extinction and Survival in Fossil Marine Invertebrates with a Special Focus on the Crinoidea (Phylum Echinodermata). [Internet] [Doctoral dissertation]. University of Michigan; 2011. [cited 2019 Dec 08]. Available from: http://hdl.handle.net/2027.42/84527.

Council of Science Editors:

Janevski GA. Causes and Consequences of Extinction and Survival in Fossil Marine Invertebrates with a Special Focus on the Crinoidea (Phylum Echinodermata). [Doctoral Dissertation]. University of Michigan; 2011. Available from: http://hdl.handle.net/2027.42/84527

15. Strachan, Ryan Thomas. P90 Ribosomal S6 Kinase 2 (RSK2) Directly Phosphorylates the 5-HT2A Serotonin Receptor thereby Modulating Signaling.

Degree: PhD, Biochemistry, 2009, Case Western Reserve University

 Given the pivotal role G protein-coupled receptors (GPCRs) play in physiological responses, various mechanisms have evolved to ensure the tight regulation of GPCR signaling. Classically,… (more)

Subjects/Keywords: Biochemistry; Pharmacology; serotonin; 5-HT; 5-HT2A; GPCR; RSK; ERK; phosphorylation; RTK; growth factor; functional selectivity; biased agonism

…Differentially Affects Agonist Signaling Thereby Promoting Altered Patterns of Functional Selectivity… …of functional selectivity. These studies ultimately led to the larger discovery that RSK2… …functional selectivity‘, has profound implications for drug discovery and will be discussed in… …x29;. However, functional experiments and low-resolution biophysical studies have provided… 

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APA (6th Edition):

Strachan, R. T. (2009). P90 Ribosomal S6 Kinase 2 (RSK2) Directly Phosphorylates the 5-HT2A Serotonin Receptor thereby Modulating Signaling. (Doctoral Dissertation). Case Western Reserve University. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=case1247172805

Chicago Manual of Style (16th Edition):

Strachan, Ryan Thomas. “P90 Ribosomal S6 Kinase 2 (RSK2) Directly Phosphorylates the 5-HT2A Serotonin Receptor thereby Modulating Signaling.” 2009. Doctoral Dissertation, Case Western Reserve University. Accessed December 08, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=case1247172805.

MLA Handbook (7th Edition):

Strachan, Ryan Thomas. “P90 Ribosomal S6 Kinase 2 (RSK2) Directly Phosphorylates the 5-HT2A Serotonin Receptor thereby Modulating Signaling.” 2009. Web. 08 Dec 2019.

Vancouver:

Strachan RT. P90 Ribosomal S6 Kinase 2 (RSK2) Directly Phosphorylates the 5-HT2A Serotonin Receptor thereby Modulating Signaling. [Internet] [Doctoral dissertation]. Case Western Reserve University; 2009. [cited 2019 Dec 08]. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=case1247172805.

Council of Science Editors:

Strachan RT. P90 Ribosomal S6 Kinase 2 (RSK2) Directly Phosphorylates the 5-HT2A Serotonin Receptor thereby Modulating Signaling. [Doctoral Dissertation]. Case Western Reserve University; 2009. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=case1247172805


Vrije Universiteit Amsterdam

16. Kooistra, A.J. In silico Medicinal Chemistry: Investigating GPCRs: key regulators of signal transduction and cell function .

Degree: 2015, Vrije Universiteit Amsterdam

Subjects/Keywords: GPCRs; virtual screening; membrane proteins; transmembrane proteins; computer-aided drug design; chemogenomics; functional selectivity; histamine receptor; adrenoceptor; antihistamine; site-directed mutagenesis; structure-affinity relationship; protein-ligand interactions; GPCR crystal structures

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APA (6th Edition):

Kooistra, A. J. (2015). In silico Medicinal Chemistry: Investigating GPCRs: key regulators of signal transduction and cell function . (Doctoral Dissertation). Vrije Universiteit Amsterdam. Retrieved from http://hdl.handle.net/1871/52308

Chicago Manual of Style (16th Edition):

Kooistra, A J. “In silico Medicinal Chemistry: Investigating GPCRs: key regulators of signal transduction and cell function .” 2015. Doctoral Dissertation, Vrije Universiteit Amsterdam. Accessed December 08, 2019. http://hdl.handle.net/1871/52308.

MLA Handbook (7th Edition):

Kooistra, A J. “In silico Medicinal Chemistry: Investigating GPCRs: key regulators of signal transduction and cell function .” 2015. Web. 08 Dec 2019.

Vancouver:

Kooistra AJ. In silico Medicinal Chemistry: Investigating GPCRs: key regulators of signal transduction and cell function . [Internet] [Doctoral dissertation]. Vrije Universiteit Amsterdam; 2015. [cited 2019 Dec 08]. Available from: http://hdl.handle.net/1871/52308.

Council of Science Editors:

Kooistra AJ. In silico Medicinal Chemistry: Investigating GPCRs: key regulators of signal transduction and cell function . [Doctoral Dissertation]. Vrije Universiteit Amsterdam; 2015. Available from: http://hdl.handle.net/1871/52308


Australian National University

17. Lording, William James. A deeper understanding of the Diels–Alder reaction .

Degree: 2014, Australian National University

 The Diels-Alder reaction was discovered in 1928 and has become the most efficient and practical method for the synthesis of six-membered carbocyclic and heterocyclic rings.… (more)

Subjects/Keywords: organic chemistry; physical organic chemistry; chemical synthesis; chemical kinetics; computational chemistry; density functional theory; DFT; nuclear magnetic resonance; NMR; Diels-Alder; Diels-Alder reaction; 4+2 cycloaddition; cycloaddition; 4+2 diene; dienophile; cyclohexene; stereochemistry; stereoselectivity; endo-exo selectivity; endo selective; exo selective; secondary orbital interaction; SOI; electrostatic interaction; butadiene; deuterium; isotopic label; kinetic isotope effect; KIE; natural abundance; transition structure; intramolecular Diels-Alder reaction; rate study; transition state; activation barrier

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APA (6th Edition):

Lording, W. J. (2014). A deeper understanding of the Diels–Alder reaction . (Thesis). Australian National University. Retrieved from http://hdl.handle.net/1885/11776

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Lording, William James. “A deeper understanding of the Diels–Alder reaction .” 2014. Thesis, Australian National University. Accessed December 08, 2019. http://hdl.handle.net/1885/11776.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Lording, William James. “A deeper understanding of the Diels–Alder reaction .” 2014. Web. 08 Dec 2019.

Vancouver:

Lording WJ. A deeper understanding of the Diels–Alder reaction . [Internet] [Thesis]. Australian National University; 2014. [cited 2019 Dec 08]. Available from: http://hdl.handle.net/1885/11776.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Lording WJ. A deeper understanding of the Diels–Alder reaction . [Thesis]. Australian National University; 2014. Available from: http://hdl.handle.net/1885/11776

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

18. Drescher, M.F. Grasping complex matter : large herbivore foraging in patches of heterogeneous resources.

Degree: 2003, Wageningen Universiteit

 Key words: herbivory; functional response; grazing; food intake; food quality; selectivity; cattle; savanna The functional response, defined as the relationship of forage intake with forage… (more)

Subjects/Keywords: herbivoren; begrazing; voedselopname; voedselkwaliteit; foerageren; ruwvoer (forage); voedingsgedrag; rundvee; savannen; functionele reacties; selectiviteit; Diervoeding en voedering (algemeen); herbivores; grazing; food intake; food quality; foraging; forage; feeding behaviour; cattle; savannas; functional responses; selectivity; Animal Nutrition and Feeding (General)

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APA (6th Edition):

Drescher, M. F. (2003). Grasping complex matter : large herbivore foraging in patches of heterogeneous resources. (Doctoral Dissertation). Wageningen Universiteit. Retrieved from http://library.wur.nl/WebQuery/wurpubs/327038 ; urn:nbn:nl:ui:32-327038 ; urn:nbn:nl:ui:32-327038 ; http://library.wur.nl/WebQuery/wurpubs/327038

Chicago Manual of Style (16th Edition):

Drescher, M F. “Grasping complex matter : large herbivore foraging in patches of heterogeneous resources.” 2003. Doctoral Dissertation, Wageningen Universiteit. Accessed December 08, 2019. http://library.wur.nl/WebQuery/wurpubs/327038 ; urn:nbn:nl:ui:32-327038 ; urn:nbn:nl:ui:32-327038 ; http://library.wur.nl/WebQuery/wurpubs/327038.

MLA Handbook (7th Edition):

Drescher, M F. “Grasping complex matter : large herbivore foraging in patches of heterogeneous resources.” 2003. Web. 08 Dec 2019.

Vancouver:

Drescher MF. Grasping complex matter : large herbivore foraging in patches of heterogeneous resources. [Internet] [Doctoral dissertation]. Wageningen Universiteit; 2003. [cited 2019 Dec 08]. Available from: http://library.wur.nl/WebQuery/wurpubs/327038 ; urn:nbn:nl:ui:32-327038 ; urn:nbn:nl:ui:32-327038 ; http://library.wur.nl/WebQuery/wurpubs/327038.

Council of Science Editors:

Drescher MF. Grasping complex matter : large herbivore foraging in patches of heterogeneous resources. [Doctoral Dissertation]. Wageningen Universiteit; 2003. Available from: http://library.wur.nl/WebQuery/wurpubs/327038 ; urn:nbn:nl:ui:32-327038 ; urn:nbn:nl:ui:32-327038 ; http://library.wur.nl/WebQuery/wurpubs/327038

.