Advanced search options

Advanced Search Options 🞨

Browse by author name (“Author name starts with…”).

Find ETDs with:

in
/  
in
/  
in
/  
in

Written in Published in Earliest date Latest date

Sorted by

Results per page:

Sorted by: relevance · author · university · dateNew search

Country:

You searched for subject:(functional selectivity). Showing records 1 – 12 of 12 total matches.

Search Limiters

Last 2 Years | English Only

No search limiters apply to these results.

▼ Search Limiters


Vanderbilt University

1. Yin, Shen. Allosteric modulation of metabotropic glutamate receptors.

Degree: PhD, Pharmacology, 2013, Vanderbilt University

 Metabotropic glutamate receptors (mGlus) are a group of Family C Seven Transmembrane Spanning Receptors that play important roles in modulating signaling transduction, particularly within the… (more)

Subjects/Keywords: heterodimerization; functional selectivity; pharmacology; allosteric modulators; mGlu

Record DetailsSimilar RecordsGoogle PlusoneFacebookTwitterCiteULikeMendeleyreddit

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Yin, S. (2013). Allosteric modulation of metabotropic glutamate receptors. (Doctoral Dissertation). Vanderbilt University. Retrieved from http://etd.library.vanderbilt.edu//available/etd-11262013-230503/ ;

Chicago Manual of Style (16th Edition):

Yin, Shen. “Allosteric modulation of metabotropic glutamate receptors.” 2013. Doctoral Dissertation, Vanderbilt University. Accessed December 09, 2019. http://etd.library.vanderbilt.edu//available/etd-11262013-230503/ ;.

MLA Handbook (7th Edition):

Yin, Shen. “Allosteric modulation of metabotropic glutamate receptors.” 2013. Web. 09 Dec 2019.

Vancouver:

Yin S. Allosteric modulation of metabotropic glutamate receptors. [Internet] [Doctoral dissertation]. Vanderbilt University; 2013. [cited 2019 Dec 09]. Available from: http://etd.library.vanderbilt.edu//available/etd-11262013-230503/ ;.

Council of Science Editors:

Yin S. Allosteric modulation of metabotropic glutamate receptors. [Doctoral Dissertation]. Vanderbilt University; 2013. Available from: http://etd.library.vanderbilt.edu//available/etd-11262013-230503/ ;


University of Kansas

2. Johnson, Stephanie. Design and Synthesis of Functionally Selective Kappa Opioid Receptor Ligands.

Degree: MS, Medicinal Chemistry, 2017, University of Kansas

 The ability of ligands to differentially regulate the activity of signaling pathways coupled to a receptor potentially enables researchers to optimize therapeutically relevant efficacies, while… (more)

Subjects/Keywords: Pharmaceutical sciences; Organic chemistry; Chemistry; functional; kappa; opioid; selectivity; U50; 488

Record DetailsSimilar RecordsGoogle PlusoneFacebookTwitterCiteULikeMendeleyreddit

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Johnson, S. (2017). Design and Synthesis of Functionally Selective Kappa Opioid Receptor Ligands. (Masters Thesis). University of Kansas. Retrieved from http://hdl.handle.net/1808/26154

Chicago Manual of Style (16th Edition):

Johnson, Stephanie. “Design and Synthesis of Functionally Selective Kappa Opioid Receptor Ligands.” 2017. Masters Thesis, University of Kansas. Accessed December 09, 2019. http://hdl.handle.net/1808/26154.

MLA Handbook (7th Edition):

Johnson, Stephanie. “Design and Synthesis of Functionally Selective Kappa Opioid Receptor Ligands.” 2017. Web. 09 Dec 2019.

Vancouver:

Johnson S. Design and Synthesis of Functionally Selective Kappa Opioid Receptor Ligands. [Internet] [Masters thesis]. University of Kansas; 2017. [cited 2019 Dec 09]. Available from: http://hdl.handle.net/1808/26154.

Council of Science Editors:

Johnson S. Design and Synthesis of Functionally Selective Kappa Opioid Receptor Ligands. [Masters Thesis]. University of Kansas; 2017. Available from: http://hdl.handle.net/1808/26154


Purdue University

3. Brust Fernandes, Tarsis. FUNCTIONAL SELECTIVITY DOWNSTREAM OF Gαi/o-COUPLED RECEPTORS.

Degree: PhD, Medicinal Chemistry and Molecular Pharmacology, 2015, Purdue University

 G protein-coupled receptors (GPCRs) are drug targets that often activate multiple signaling pathways. The multiple GPCR responses provide opportunities for biased or functionally selective ligands… (more)

Subjects/Keywords: adenylyl cyclase; beta-arrestin; biased signaling; functional selectivity; GPCR; G protein

Record DetailsSimilar RecordsGoogle PlusoneFacebookTwitterCiteULikeMendeleyreddit

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Brust Fernandes, T. (2015). FUNCTIONAL SELECTIVITY DOWNSTREAM OF Gαi/o-COUPLED RECEPTORS. (Doctoral Dissertation). Purdue University. Retrieved from https://docs.lib.purdue.edu/open_access_dissertations/1448

Chicago Manual of Style (16th Edition):

Brust Fernandes, Tarsis. “FUNCTIONAL SELECTIVITY DOWNSTREAM OF Gαi/o-COUPLED RECEPTORS.” 2015. Doctoral Dissertation, Purdue University. Accessed December 09, 2019. https://docs.lib.purdue.edu/open_access_dissertations/1448.

MLA Handbook (7th Edition):

Brust Fernandes, Tarsis. “FUNCTIONAL SELECTIVITY DOWNSTREAM OF Gαi/o-COUPLED RECEPTORS.” 2015. Web. 09 Dec 2019.

Vancouver:

Brust Fernandes T. FUNCTIONAL SELECTIVITY DOWNSTREAM OF Gαi/o-COUPLED RECEPTORS. [Internet] [Doctoral dissertation]. Purdue University; 2015. [cited 2019 Dec 09]. Available from: https://docs.lib.purdue.edu/open_access_dissertations/1448.

Council of Science Editors:

Brust Fernandes T. FUNCTIONAL SELECTIVITY DOWNSTREAM OF Gαi/o-COUPLED RECEPTORS. [Doctoral Dissertation]. Purdue University; 2015. Available from: https://docs.lib.purdue.edu/open_access_dissertations/1448


The Ohio State University

4. Schmid, Cullen L. Differential regulation of serotonin 2A receptor responsiveness by agonist-directed interactions with beta-arrestin2.

Degree: PhD, Neuroscience Graduate Studies Program, 2011, The Ohio State University

 The G protein-coupled, serotonin 2A (5-HT2A) receptor is a major drug target for the treatment of a number of mental health disorders, including schizophrenia, anxiety… (more)

Subjects/Keywords: Neurosciences; Pharmacology; G protein-coupled receptor; Serotonin 2A receptor; beta-arrestin2; hallucinogens; functional selectivity

Record DetailsSimilar RecordsGoogle PlusoneFacebookTwitterCiteULikeMendeleyreddit

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Schmid, C. L. (2011). Differential regulation of serotonin 2A receptor responsiveness by agonist-directed interactions with beta-arrestin2. (Doctoral Dissertation). The Ohio State University. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=osu1300287547

Chicago Manual of Style (16th Edition):

Schmid, Cullen L. “Differential regulation of serotonin 2A receptor responsiveness by agonist-directed interactions with beta-arrestin2.” 2011. Doctoral Dissertation, The Ohio State University. Accessed December 09, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=osu1300287547.

MLA Handbook (7th Edition):

Schmid, Cullen L. “Differential regulation of serotonin 2A receptor responsiveness by agonist-directed interactions with beta-arrestin2.” 2011. Web. 09 Dec 2019.

Vancouver:

Schmid CL. Differential regulation of serotonin 2A receptor responsiveness by agonist-directed interactions with beta-arrestin2. [Internet] [Doctoral dissertation]. The Ohio State University; 2011. [cited 2019 Dec 09]. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=osu1300287547.

Council of Science Editors:

Schmid CL. Differential regulation of serotonin 2A receptor responsiveness by agonist-directed interactions with beta-arrestin2. [Doctoral Dissertation]. The Ohio State University; 2011. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=osu1300287547


UCLA

5. Yu, Peiyuan. Computational Studies on the Reactivity, Selectivity and Molecular Dynamics of Cycloaddition Reactions.

Degree: Chemistry, 2017, UCLA

 The first part of this dissertation describes computational studies of higher-order cycloadditions with a focus on elucidating the origins of periselectivity. These reactions involve ambimodal… (more)

Subjects/Keywords: Chemistry; Organic chemistry; Cycloaddition; Density Functional Theory; Diels–Alder; Molecular Dynamics; Reactivity; Selectivity

Record DetailsSimilar RecordsGoogle PlusoneFacebookTwitterCiteULikeMendeleyreddit

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Yu, P. (2017). Computational Studies on the Reactivity, Selectivity and Molecular Dynamics of Cycloaddition Reactions. (Thesis). UCLA. Retrieved from http://www.escholarship.org/uc/item/1jk894mq

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Yu, Peiyuan. “Computational Studies on the Reactivity, Selectivity and Molecular Dynamics of Cycloaddition Reactions.” 2017. Thesis, UCLA. Accessed December 09, 2019. http://www.escholarship.org/uc/item/1jk894mq.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Yu, Peiyuan. “Computational Studies on the Reactivity, Selectivity and Molecular Dynamics of Cycloaddition Reactions.” 2017. Web. 09 Dec 2019.

Vancouver:

Yu P. Computational Studies on the Reactivity, Selectivity and Molecular Dynamics of Cycloaddition Reactions. [Internet] [Thesis]. UCLA; 2017. [cited 2019 Dec 09]. Available from: http://www.escholarship.org/uc/item/1jk894mq.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Yu P. Computational Studies on the Reactivity, Selectivity and Molecular Dynamics of Cycloaddition Reactions. [Thesis]. UCLA; 2017. Available from: http://www.escholarship.org/uc/item/1jk894mq

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation


University of Arizona

6. Olson, Keith Mathew. Atypical Opioid Interactions – Development of Selective Mu-Delta Heterodimer Antagonists, Clinical Opioids at Non-Mu Pain Targets and Endogenous Biased Signaling .

Degree: 2017, University of Arizona

 Most clinical opioids produce analgesia through the Mu Opioid Receptor (MOR) providing the only effective treatment for chronic pain patients. These studies explore three pre-clinical… (more)

Subjects/Keywords: Bivalent; Delta Opioid Receptor; Functional Selectivity; MDOR Heterodimer; Mu Opioid Receptor; Opioid Signaling

Record DetailsSimilar RecordsGoogle PlusoneFacebookTwitterCiteULikeMendeleyreddit

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Olson, K. M. (2017). Atypical Opioid Interactions – Development of Selective Mu-Delta Heterodimer Antagonists, Clinical Opioids at Non-Mu Pain Targets and Endogenous Biased Signaling . (Doctoral Dissertation). University of Arizona. Retrieved from http://hdl.handle.net/10150/626669

Chicago Manual of Style (16th Edition):

Olson, Keith Mathew. “Atypical Opioid Interactions – Development of Selective Mu-Delta Heterodimer Antagonists, Clinical Opioids at Non-Mu Pain Targets and Endogenous Biased Signaling .” 2017. Doctoral Dissertation, University of Arizona. Accessed December 09, 2019. http://hdl.handle.net/10150/626669.

MLA Handbook (7th Edition):

Olson, Keith Mathew. “Atypical Opioid Interactions – Development of Selective Mu-Delta Heterodimer Antagonists, Clinical Opioids at Non-Mu Pain Targets and Endogenous Biased Signaling .” 2017. Web. 09 Dec 2019.

Vancouver:

Olson KM. Atypical Opioid Interactions – Development of Selective Mu-Delta Heterodimer Antagonists, Clinical Opioids at Non-Mu Pain Targets and Endogenous Biased Signaling . [Internet] [Doctoral dissertation]. University of Arizona; 2017. [cited 2019 Dec 09]. Available from: http://hdl.handle.net/10150/626669.

Council of Science Editors:

Olson KM. Atypical Opioid Interactions – Development of Selective Mu-Delta Heterodimer Antagonists, Clinical Opioids at Non-Mu Pain Targets and Endogenous Biased Signaling . [Doctoral Dissertation]. University of Arizona; 2017. Available from: http://hdl.handle.net/10150/626669


Georgia Tech

7. Pak, Richard. An investigation of perceptual load, aging, and the functional field of view.

Degree: PhD, Psychology, 2005, Georgia Tech

 A common metaphor for visual attention is the spotlight (Posner, 1980). It follows from the spotlight metaphor and other similar models (e.g., zoom-lens model; Eriksen… (more)

Subjects/Keywords: Perceptual load; FFOV; Aging; Functional field of view; Selectivity (Psychology); Visual perception; Aging; Attention

Record DetailsSimilar RecordsGoogle PlusoneFacebookTwitterCiteULikeMendeleyreddit

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Pak, R. (2005). An investigation of perceptual load, aging, and the functional field of view. (Doctoral Dissertation). Georgia Tech. Retrieved from http://hdl.handle.net/1853/7585

Chicago Manual of Style (16th Edition):

Pak, Richard. “An investigation of perceptual load, aging, and the functional field of view.” 2005. Doctoral Dissertation, Georgia Tech. Accessed December 09, 2019. http://hdl.handle.net/1853/7585.

MLA Handbook (7th Edition):

Pak, Richard. “An investigation of perceptual load, aging, and the functional field of view.” 2005. Web. 09 Dec 2019.

Vancouver:

Pak R. An investigation of perceptual load, aging, and the functional field of view. [Internet] [Doctoral dissertation]. Georgia Tech; 2005. [cited 2019 Dec 09]. Available from: http://hdl.handle.net/1853/7585.

Council of Science Editors:

Pak R. An investigation of perceptual load, aging, and the functional field of view. [Doctoral Dissertation]. Georgia Tech; 2005. Available from: http://hdl.handle.net/1853/7585


University of California – San Francisco

8. Chang, Wei Chun. Controlling the Agonist-Mediated and Constitutive G-Protein Signaling of the Human 5-HT4 Receptor.

Degree: Pharmaceutical Sciences and Pharmacogenomics, 2007, University of California – San Francisco

 G-protein-coupled receptors (GPCRs) signal through a limited number of G-protein pathways and are crucial in many biological processes. The molecular and functional diversity of GPCRs… (more)

Subjects/Keywords: Biology, Cell; GPCR; RASSL; 5HT4; domain swapping; chimera; G protein signaling; agonist mediated; constitutive signaling; functional selectivity

Record DetailsSimilar RecordsGoogle PlusoneFacebookTwitterCiteULikeMendeleyreddit

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Chang, W. C. (2007). Controlling the Agonist-Mediated and Constitutive G-Protein Signaling of the Human 5-HT4 Receptor. (Thesis). University of California – San Francisco. Retrieved from http://www.escholarship.org/uc/item/6hf4j89w

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Chang, Wei Chun. “Controlling the Agonist-Mediated and Constitutive G-Protein Signaling of the Human 5-HT4 Receptor.” 2007. Thesis, University of California – San Francisco. Accessed December 09, 2019. http://www.escholarship.org/uc/item/6hf4j89w.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Chang, Wei Chun. “Controlling the Agonist-Mediated and Constitutive G-Protein Signaling of the Human 5-HT4 Receptor.” 2007. Web. 09 Dec 2019.

Vancouver:

Chang WC. Controlling the Agonist-Mediated and Constitutive G-Protein Signaling of the Human 5-HT4 Receptor. [Internet] [Thesis]. University of California – San Francisco; 2007. [cited 2019 Dec 09]. Available from: http://www.escholarship.org/uc/item/6hf4j89w.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Chang WC. Controlling the Agonist-Mediated and Constitutive G-Protein Signaling of the Human 5-HT4 Receptor. [Thesis]. University of California – San Francisco; 2007. Available from: http://www.escholarship.org/uc/item/6hf4j89w

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

9. Janevski, G. Alex. Causes and Consequences of Extinction and Survival in Fossil Marine Invertebrates with a Special Focus on the Crinoidea (Phylum Echinodermata).

Degree: PhD, Geology, 2011, University of Michigan

 In the geologic past, certain traits increased the chance of survival of some marine invertebrate taxa, which means that extinction did not occur randomly. However,… (more)

Subjects/Keywords: Extinction Selectivity; Phylogeny; Crinoids; Marine Invertebrates; Biomechanics; Functional Morphology; Geology and Earth Sciences; Science

…Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . Functional morphology of swimming… …selectivity increases . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Observed extinction… …the contribution of regional selectivity to observed extinction selectivity patterns… …ix 19 36 53 91 91 104 LIST OF APPENDICES Appendix A. Evidence for selectivity for… …the P-Tr extinction event? Did extinction selectivity affect crinoids during this event? The… 

Record DetailsSimilar RecordsGoogle PlusoneFacebookTwitterCiteULikeMendeleyreddit

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Janevski, G. A. (2011). Causes and Consequences of Extinction and Survival in Fossil Marine Invertebrates with a Special Focus on the Crinoidea (Phylum Echinodermata). (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/84527

Chicago Manual of Style (16th Edition):

Janevski, G Alex. “Causes and Consequences of Extinction and Survival in Fossil Marine Invertebrates with a Special Focus on the Crinoidea (Phylum Echinodermata).” 2011. Doctoral Dissertation, University of Michigan. Accessed December 09, 2019. http://hdl.handle.net/2027.42/84527.

MLA Handbook (7th Edition):

Janevski, G Alex. “Causes and Consequences of Extinction and Survival in Fossil Marine Invertebrates with a Special Focus on the Crinoidea (Phylum Echinodermata).” 2011. Web. 09 Dec 2019.

Vancouver:

Janevski GA. Causes and Consequences of Extinction and Survival in Fossil Marine Invertebrates with a Special Focus on the Crinoidea (Phylum Echinodermata). [Internet] [Doctoral dissertation]. University of Michigan; 2011. [cited 2019 Dec 09]. Available from: http://hdl.handle.net/2027.42/84527.

Council of Science Editors:

Janevski GA. Causes and Consequences of Extinction and Survival in Fossil Marine Invertebrates with a Special Focus on the Crinoidea (Phylum Echinodermata). [Doctoral Dissertation]. University of Michigan; 2011. Available from: http://hdl.handle.net/2027.42/84527

10. Karpinsky-Semper, Darla. The Structural Basis of Gβ5-RGS7 Interaction with the Muscarinic M3 Receptor and Implications for its Role in Functional Pathway Selectivity.

Degree: PhD, Molecular and Cellular Pharmacology (Medicine), 2014, University of Miami

  The neurotransmitter acetylcholine (Ach) is arguably the most important in the CNS. Two classes of receptors are activated by Ach: nicotinic (ionotropic) and muscarinic… (more)

Subjects/Keywords: Gβ5-RGS7; G protein-coupled receptor; muscarinic M3 receptor; Ca2+ signaling; functional selectivity

…conferred functional selectivity of M3R regulation by Gβ5-RGS7… …Fig. 3.16). The terms biased agonism, functional selectivity, agonist trafficking or… …ligand bias are interchangeable. Functional selectivity is not only a consequence of receptor G… …4.4 The central 85 amino acids of the M3R i3 loop may dictate selectivity for Gβ5-RGS7… …different G proteins identified specific receptor regions involved in selectivity of G protein… 

Record DetailsSimilar RecordsGoogle PlusoneFacebookTwitterCiteULikeMendeleyreddit

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Karpinsky-Semper, D. (2014). The Structural Basis of Gβ5-RGS7 Interaction with the Muscarinic M3 Receptor and Implications for its Role in Functional Pathway Selectivity. (Doctoral Dissertation). University of Miami. Retrieved from https://scholarlyrepository.miami.edu/oa_dissertations/1312

Chicago Manual of Style (16th Edition):

Karpinsky-Semper, Darla. “The Structural Basis of Gβ5-RGS7 Interaction with the Muscarinic M3 Receptor and Implications for its Role in Functional Pathway Selectivity.” 2014. Doctoral Dissertation, University of Miami. Accessed December 09, 2019. https://scholarlyrepository.miami.edu/oa_dissertations/1312.

MLA Handbook (7th Edition):

Karpinsky-Semper, Darla. “The Structural Basis of Gβ5-RGS7 Interaction with the Muscarinic M3 Receptor and Implications for its Role in Functional Pathway Selectivity.” 2014. Web. 09 Dec 2019.

Vancouver:

Karpinsky-Semper D. The Structural Basis of Gβ5-RGS7 Interaction with the Muscarinic M3 Receptor and Implications for its Role in Functional Pathway Selectivity. [Internet] [Doctoral dissertation]. University of Miami; 2014. [cited 2019 Dec 09]. Available from: https://scholarlyrepository.miami.edu/oa_dissertations/1312.

Council of Science Editors:

Karpinsky-Semper D. The Structural Basis of Gβ5-RGS7 Interaction with the Muscarinic M3 Receptor and Implications for its Role in Functional Pathway Selectivity. [Doctoral Dissertation]. University of Miami; 2014. Available from: https://scholarlyrepository.miami.edu/oa_dissertations/1312

11. Peterson, Sean Michael. Functional Selectivity at the Dopamine D2 Receptor .

Degree: 2015, Duke University

  The neuromodulator dopamine signals through the dopamine D2 receptor (D2R) to modulate central nervous system functions through diverse signal transduction pathways. D2R is a… (more)

Subjects/Keywords: Cellular biology; Pharmacology; Dopamine; Functional Selectivity; GPCR; G protein; β-arrestin

…36 Table II: Evolutionary Action predicted functional selectivity phenotype mutations in… …91 Table IV: Receptor manipulations yield operationally defined functional selectivity… …Ligand contributions to functional selectivity. Calculated from Figures 9 and 10. *p<0.05 when… …Table VI: Transducer contributions to functional selectivity. Calculated from Figure 11. *p… …94 viii List of Figures Figure 1: The functional selectivity of D2R. (A)… 

Record DetailsSimilar RecordsGoogle PlusoneFacebookTwitterCiteULikeMendeleyreddit

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Peterson, S. M. (2015). Functional Selectivity at the Dopamine D2 Receptor . (Thesis). Duke University. Retrieved from http://hdl.handle.net/10161/10500

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Peterson, Sean Michael. “Functional Selectivity at the Dopamine D2 Receptor .” 2015. Thesis, Duke University. Accessed December 09, 2019. http://hdl.handle.net/10161/10500.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Peterson, Sean Michael. “Functional Selectivity at the Dopamine D2 Receptor .” 2015. Web. 09 Dec 2019.

Vancouver:

Peterson SM. Functional Selectivity at the Dopamine D2 Receptor . [Internet] [Thesis]. Duke University; 2015. [cited 2019 Dec 09]. Available from: http://hdl.handle.net/10161/10500.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Peterson SM. Functional Selectivity at the Dopamine D2 Receptor . [Thesis]. Duke University; 2015. Available from: http://hdl.handle.net/10161/10500

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

12. Strachan, Ryan Thomas. P90 Ribosomal S6 Kinase 2 (RSK2) Directly Phosphorylates the 5-HT2A Serotonin Receptor thereby Modulating Signaling.

Degree: PhD, Biochemistry, 2009, Case Western Reserve University

 Given the pivotal role G protein-coupled receptors (GPCRs) play in physiological responses, various mechanisms have evolved to ensure the tight regulation of GPCR signaling. Classically,… (more)

Subjects/Keywords: Biochemistry; Pharmacology; serotonin; 5-HT; 5-HT2A; GPCR; RSK; ERK; phosphorylation; RTK; growth factor; functional selectivity; biased agonism

…Differentially Affects Agonist Signaling Thereby Promoting Altered Patterns of Functional Selectivity… …of functional selectivity. These studies ultimately led to the larger discovery that RSK2… …functional selectivity‘, has profound implications for drug discovery and will be discussed in… …x29;. However, functional experiments and low-resolution biophysical studies have provided… 

Record DetailsSimilar RecordsGoogle PlusoneFacebookTwitterCiteULikeMendeleyreddit

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Strachan, R. T. (2009). P90 Ribosomal S6 Kinase 2 (RSK2) Directly Phosphorylates the 5-HT2A Serotonin Receptor thereby Modulating Signaling. (Doctoral Dissertation). Case Western Reserve University. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=case1247172805

Chicago Manual of Style (16th Edition):

Strachan, Ryan Thomas. “P90 Ribosomal S6 Kinase 2 (RSK2) Directly Phosphorylates the 5-HT2A Serotonin Receptor thereby Modulating Signaling.” 2009. Doctoral Dissertation, Case Western Reserve University. Accessed December 09, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=case1247172805.

MLA Handbook (7th Edition):

Strachan, Ryan Thomas. “P90 Ribosomal S6 Kinase 2 (RSK2) Directly Phosphorylates the 5-HT2A Serotonin Receptor thereby Modulating Signaling.” 2009. Web. 09 Dec 2019.

Vancouver:

Strachan RT. P90 Ribosomal S6 Kinase 2 (RSK2) Directly Phosphorylates the 5-HT2A Serotonin Receptor thereby Modulating Signaling. [Internet] [Doctoral dissertation]. Case Western Reserve University; 2009. [cited 2019 Dec 09]. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=case1247172805.

Council of Science Editors:

Strachan RT. P90 Ribosomal S6 Kinase 2 (RSK2) Directly Phosphorylates the 5-HT2A Serotonin Receptor thereby Modulating Signaling. [Doctoral Dissertation]. Case Western Reserve University; 2009. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=case1247172805

.