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NSYSU
1.
Kao, Hui-yu.
The Distribution of Alkylphenol Polyethoxylates in the Sediments of the Coastal Areas Along the Southwestern Taiwan.
Degree: Master, Marine Environment and Engineering, 2015, NSYSU
URL: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0719115-235550
► This study investigated spatial distribution and seasonal variation of alkylphenol (APs) in the sediments of the coastal areas along the southwestern Taiwan. The comparison of…
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▼ This study investigated spatial distribution and seasonal variation of alkylphenol (APs) in the sediments of the coastal areas along the southwestern Taiwan. The comparison of AP concentrations was also made between river sediments and coastal sediments of southwestern Taiwan to get a better understanding on the current status of APs in Taiwan. Sediment samples were extracted with a solid phase extraction (SPE) method and analyzed by high-performance liquid-chromatography tandem mass spectrometry (HPLC-MS/MS). Principal Component Analysis (PCA) and Hierarchical Cluster Analysis (HCA) were also performed to determine the potential sources of APs.
ããTotal concentration of APs in coastal sediments ranged from 1.16 to 353 ng/g dry weight in dry season and from ND to 296 ng/g dry weight in wet season. The highest AP concentration was observed at Kaohsiung coastal area in dry season while the highest AP concentration in wet season was found at Tainan coastal area. Total concentration of APs in river sediments ranged from 8.85 to 952 ng/g dry weight in dry season. Total AP level in coastal sediments were much lower than those in river sediments. NP was detected in the sediment samples both in the dry and wet seasons. In comparison with global studies, the concentrations of APs in this study were both at low levels for sediments from coastal areas and Gaping River, but were at moderate levels for sediments from Tainan Canal.
ããAP concentrations showed a significant correlation with total organic carbon (TOC), but no correlation was observed between AP concentrations and particle size. Comparing with predicted no-effect concentrations (PNECs) proposed by European Union (EU), APs might pose a potential risk to the aquatic environment. The results of multivariate statistical analysis indicated that, AP groups were clustered based on the loading of NP, and both PCA and HCA gave a similar result in the studied areas.
Advisors/Committee Members: Chon-Lin Lee (committee member), Meng-Der Fang (chair), Chin-Hsing Lai (chair), Shui-Jen Chen (chair).
Subjects/Keywords: Alkylphenols; Endocrine disrupting compounds; Sediment; Nonylphenol; Octylphenol
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APA (6th Edition):
Kao, H. (2015). The Distribution of Alkylphenol Polyethoxylates in the Sediments of the Coastal Areas Along the Southwestern Taiwan. (Thesis). NSYSU. Retrieved from http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0719115-235550
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Kao, Hui-yu. “The Distribution of Alkylphenol Polyethoxylates in the Sediments of the Coastal Areas Along the Southwestern Taiwan.” 2015. Thesis, NSYSU. Accessed January 27, 2021.
http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0719115-235550.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Kao, Hui-yu. “The Distribution of Alkylphenol Polyethoxylates in the Sediments of the Coastal Areas Along the Southwestern Taiwan.” 2015. Web. 27 Jan 2021.
Vancouver:
Kao H. The Distribution of Alkylphenol Polyethoxylates in the Sediments of the Coastal Areas Along the Southwestern Taiwan. [Internet] [Thesis]. NSYSU; 2015. [cited 2021 Jan 27].
Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0719115-235550.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Kao H. The Distribution of Alkylphenol Polyethoxylates in the Sediments of the Coastal Areas Along the Southwestern Taiwan. [Thesis]. NSYSU; 2015. Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0719115-235550
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of the Western Cape
2.
Baguma, Richard.
Comparison between chemical and tissue culture methods to monitor environmental estrogens
.
Degree: 2012, University of the Western Cape
URL: http://hdl.handle.net/11394/5107
► Endocrine disrupting compounds (EDCs) are exogenous compounds/chemicals in the environment that interfere with the synthesis, secretion, distribution and function or elimination of natural hormones in…
(more)
▼ Endocrine disrupting compounds (EDCs) are exogenous
compounds/chemicals in the environment that interfere with the synthesis, secretion, distribution and function or elimination of natural hormones in the body. Environmental estrogens are a subclass of EDCs that may mimic or inhibit the effect of endogenous estrogen and can therefore influence developmental and reproductive health in humans and animals. EDCs have been reported to adversely affect the reproductive, immune,
endocrine and nervous systems of wildlife and humans. The effects of EDCs include gonadal abnormalities, altered male/female sex ratios, reduced fertility and cancers of the male and female reproductive tract to mention a few. These effects are difficult to detect. Although it is essential to screen for EDCs in aqueous environmental samples, most countries have failed to implement this as part of their routine water quality monitoring programs due to various constraints such as the high cost of assays and the lack of infrastructure and skills required to do the assays. Therefore, there is a clear need for more user-friendly, more economically viable and time saving assays that can be used for routine monitoring of environmental EDCs. The aim of this study was to investigate the comparison between chemical and tissue culture methods to monitor environmental estrogens. 28 environmental water samples were collected from various sites around South Africa and analyzed for EDCs using a battery of rapid in vitro tests. Samples collected for the current study were selected based on various human impacts and also to give approximately 50% high and 50% low estrogen values. The 28 environmental water samples were separated into two groups based on the estradiol ELISA. The estradiol ELISA was chosen because estradiol is the principal estrogen found in all mammalian species during their reproductive years. For this separation, an estradiol level of 5 pg/ml was used as cut-off. Of the 28 samples investigated, 15 had estradiol levels higher than 5 pg/ml and were designated as high estradiol. The remaining 13 samples contained estradiol at 5 pg/ml or less and they were designated as low estradiol. The first objective of this study was to compare different rapid ELISAs for EDC monitoring to determine if the data obtained with these assays are similar/identical. The data obtained from the estrogenic ELISAs was related/similar and showed good correlation with each other. This is because the different estrogens are very similar and also due to the fact that the same sub-group in the population (the reproductively active females) is secreting these hormones. Therefore, an estradiol rapid assay was proposed as a first screening system for estrogens in samples. Even though there was a positive correlation between the estradiol rapid assay and testosterone rapid assay, separation of samples based on estradiol levels wasn’t a good predictor of testosterone levels in the samples. A testosterone rapid assay was therefore recommended as necessary to screen for androgens in…
Advisors/Committee Members: Pool, Edmund J (advisor).
Subjects/Keywords: Bioassay;
Estrogens;
Steroidogenesis;
Pollution;
Endocrine disrupting compounds
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Baguma, R. (2012). Comparison between chemical and tissue culture methods to monitor environmental estrogens
. (Thesis). University of the Western Cape. Retrieved from http://hdl.handle.net/11394/5107
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Baguma, Richard. “Comparison between chemical and tissue culture methods to monitor environmental estrogens
.” 2012. Thesis, University of the Western Cape. Accessed January 27, 2021.
http://hdl.handle.net/11394/5107.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Baguma, Richard. “Comparison between chemical and tissue culture methods to monitor environmental estrogens
.” 2012. Web. 27 Jan 2021.
Vancouver:
Baguma R. Comparison between chemical and tissue culture methods to monitor environmental estrogens
. [Internet] [Thesis]. University of the Western Cape; 2012. [cited 2021 Jan 27].
Available from: http://hdl.handle.net/11394/5107.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Baguma R. Comparison between chemical and tissue culture methods to monitor environmental estrogens
. [Thesis]. University of the Western Cape; 2012. Available from: http://hdl.handle.net/11394/5107
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Georgia
3.
Namulanda, Gonza.
In utero exposure to organochlorine and atrazine pesticides and early menarche in the Avon Longitudinal Study on Parents and Children cohort.
Degree: 2017, University of Georgia
URL: http://hdl.handle.net/10724/36831
► Introduction: Pesticides are toxic substances that can also cause unintended adverse effects, e.g., endocrine disruption, in exposed non-target populations such as humans. Some endocrine disrupting…
(more)
▼ Introduction: Pesticides are toxic substances that can also cause unintended adverse effects, e.g., endocrine disruption, in exposed non-target populations such as humans. Some endocrine disrupting compounds (EDCs) (e.g., the organochlorine
pesticide dichlorodiphenyltrichloroethane (DDT)) are identified as persistent organic pollutants while other suspected EDCs (e.g., atrazine) are less persistent in the body. A trend towards early puberty in girls has been observed in the United States
and Europe. This decline in the age of onset of puberty has been associated with several factors including exposures to EDCs. The endocrine disrupting effects due to population exposures to pesticides are still not well understood. Objectives: 1) To
characterize the in utero exposure of girls in the Avon Longitudinal Study on Parents and Children (ALSPAC) in Bristol, United Kingdom (UK) to organochlorine pesticides and examine the association with early menarche 2) To characterize the in utero
exposure of girls in ALSPAC to atrazine pesticide and examine the association with early menarche. Methods: Exposure to 9 organochlorine compounds and 7 atrazine analytes measured in maternal serum or urine collected during pregnancy was characterized
using non-parametric survival analysis methods. Logistic regression methods were used to examine the association between in utero exposure to these pesticides and early menarche. Results: Hexacholorbenzene (HCB), β-hexacholorocyclohexane (β-HCH),
2,2-Bis(4-chlorophenyl)-1,1,1-trichloroethane (p,p’-DDT) and 2,2-Bis(4-chlorophenyl)-1,1-dichloroethene (p,p’-DDE) were detected in more than 50% of the study participants. Diaminochlorotriazine (DACT) was the only atrazine analyte detected in more than
50% of the study participants. Overall, there was no association between in utero exposure to organochlorines and early menarche. In utero exposure to higher levels of the atrazine metabolite DACT in the ALSPAC cohort was associated with an increased
odds of early menarche. Conclusions: More emphasis needs to be placed on measuring exposure in countries where organochlorine pesticides are still in use and evaluating their associations with adverse health effects. Our results suggest an association
between in utero exposure to the atrazine metabolite DACT and early menarche in the ALSPAC cohort. To accurately assess atrazine exposure in populations, several metabolites including DACT need to be measured.
Subjects/Keywords: Endocrine disrupting compounds; ALSPAC; menarche; early puberty
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Namulanda, G. (2017). In utero exposure to organochlorine and atrazine pesticides and early menarche in the Avon Longitudinal Study on Parents and Children cohort. (Thesis). University of Georgia. Retrieved from http://hdl.handle.net/10724/36831
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Namulanda, Gonza. “In utero exposure to organochlorine and atrazine pesticides and early menarche in the Avon Longitudinal Study on Parents and Children cohort.” 2017. Thesis, University of Georgia. Accessed January 27, 2021.
http://hdl.handle.net/10724/36831.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Namulanda, Gonza. “In utero exposure to organochlorine and atrazine pesticides and early menarche in the Avon Longitudinal Study on Parents and Children cohort.” 2017. Web. 27 Jan 2021.
Vancouver:
Namulanda G. In utero exposure to organochlorine and atrazine pesticides and early menarche in the Avon Longitudinal Study on Parents and Children cohort. [Internet] [Thesis]. University of Georgia; 2017. [cited 2021 Jan 27].
Available from: http://hdl.handle.net/10724/36831.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Namulanda G. In utero exposure to organochlorine and atrazine pesticides and early menarche in the Avon Longitudinal Study on Parents and Children cohort. [Thesis]. University of Georgia; 2017. Available from: http://hdl.handle.net/10724/36831
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Massey University
4.
Zia, Asif Iqbal.
Smart electrochemical sensing system for the real time detection of endocrine disrupting compounds and hormones.
Degree: PhD, Electronics Engineering, 2015, Massey University
URL: http://hdl.handle.net/10179/6680
► Presented research work has not only provided a real-time tool to perform week-long chemical and bio-chemical assays in minutes yet, it had been operating as…
(more)
▼ Presented research work has not only provided a real-time tool to perform week-long chemical and bio-chemical assays in minutes yet, it had been operating as a source of community awareness about the said chemicals that we keep ingesting knowing or unknowingly. Phthalates are the most ubiquitous chemicals that pose a grave danger to the human race due to their extraordinary use as plasticizer in consumer product industry. All contemporary detection methods require high level of skills, expensive equipment and long analysis time as compared to the technique presented in this research work that introduces a real time non-invasive assay. A novel type of silicon substrate based smart interdigital sensor fabricated by employing thin film micro-electromechanical system semiconductor device fabrication technology. Electrochemical Impedance Spectroscopy was used in conjunction with the fabricated sensor to detect hormones and phthalates in deionized water. Various concentrations of phthalates as low as 2 parts per billion to a higher level of 2 parts per million in deionized water were detected distinctively using new planar ID sensor based EIS sensing system. The sensor was functionalized by a self-assembled monolayer of 3-aminopropyltrietoxysilane with embedded molecular imprinted polymer to introduce selectivity for the phthalate molecule. Spectrum analysis algorithm interpreted the experimentally obtained impedance spectra by applying complex nonlinear least square curve fitting in order to obtain electrochemical equivalent circuit and corresponding circuit parameters describing the kinetics of the electrochemical cell. Principal component analysis was applied to deduce the effects of surface immobilized molecular imprinted polymer layer on the evaluated circuit parameters and its electrical response. The results obtained by the testing system were validated using commercially available high performance liquid chromatography diode array detector system.
Subjects/Keywords: Electrochemical analysis;
Impedance spectroscopy;
Water analysis;
Beverages;
Analysis;
Phthalate esters;
Endocrine disrupting hormones;
Endocrine disrupting compounds
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Zia, A. I. (2015). Smart electrochemical sensing system for the real time detection of endocrine disrupting compounds and hormones. (Doctoral Dissertation). Massey University. Retrieved from http://hdl.handle.net/10179/6680
Chicago Manual of Style (16th Edition):
Zia, Asif Iqbal. “Smart electrochemical sensing system for the real time detection of endocrine disrupting compounds and hormones.” 2015. Doctoral Dissertation, Massey University. Accessed January 27, 2021.
http://hdl.handle.net/10179/6680.
MLA Handbook (7th Edition):
Zia, Asif Iqbal. “Smart electrochemical sensing system for the real time detection of endocrine disrupting compounds and hormones.” 2015. Web. 27 Jan 2021.
Vancouver:
Zia AI. Smart electrochemical sensing system for the real time detection of endocrine disrupting compounds and hormones. [Internet] [Doctoral dissertation]. Massey University; 2015. [cited 2021 Jan 27].
Available from: http://hdl.handle.net/10179/6680.
Council of Science Editors:
Zia AI. Smart electrochemical sensing system for the real time detection of endocrine disrupting compounds and hormones. [Doctoral Dissertation]. Massey University; 2015. Available from: http://hdl.handle.net/10179/6680

University of Adelaide
5.
Langdon, Kate Alison.
Environmental behaviour of pharmaceuticals, personal care products and endocrine disrupting compounds following land application of biosolids.
Degree: 2010, University of Adelaide
URL: http://hdl.handle.net/2440/65255
► The reuse of biosolids through application onto agricultural land has been shown to provide plants with additional nutrients and organic carbon and improve moisture retention…
(more)
▼ The reuse of biosolids through application onto agricultural land has been shown to provide plants with additional nutrients and organic carbon and improve moisture retention in soils. This practice can however be a route of entry into the environment for numerous contaminants that may be contained within the biosolids. The work presented in this thesis aims to gain a better understanding of the environmental behaviour of pharmaceuticals and personal care products (PPCPs) and
endocrine disrupting compounds (EDCs) following the addition of biosolids to land. This work involved initially conducting an aquatic hazard assessment for PPCPs and EDCs following biosolids addition to land. Following this, seven
compounds were selected, 4-nonylphenol (4NP), 4-t-octylphenol (4tOP), bisphenol A (BPA), triclosan (TCS), 17β-estradiol (E2), estrone (E1), estriol (E3) and 17α-ethinylestradiol (EE2), for an Australian biosolids survey. Four of these
compounds were then chosen (i.e. 4NP, 4tOP, BPA and TCS) for a series of experiments assessing their dissipation (i.e. decreases in concentration) following the addition of biosolids to soil in the laboratory and in the field, as well as the suitability of using spiking experiments (i.e. spiking elevated concentrations of
compounds into a soil and biosolids sample) to predict the persistence of these
compounds following biosolids addition. Finally, the yeast estrogen screen (YES) bioassay was conducted on several soil sample extracts from the field trial to determine if estrogenic activity could be measured in soils following biosolids addition. The results from the hazard assessment showed that the majority of PPCPs and EDCs that have been detected in biosolids pose low hazard to adjacent aquatic ecosystems. However, there were ten
compounds that posed a high hazard and therefore warrant further investigation. These
compounds were the fragrance
compounds, tonalide and galaxolide, the estrogen
compounds, 17β-estradiol and 17α ethinylestradiol, the antibiotic
compounds ciprofloxacin, doxycycline and norfloxacin and the antimicrobial agents triclosan and triclocarban. The survey of Australian biosolids detected concentrations of 0.35 to 513 mg/kg for 4NP, 0.05 to 3.08 mg/kg for 4tOP, < 0.01 to 11.2 mg/kg for TCS, < 0.01 to 1.47 mg/kg for BPA and < 0.05 to 0.37 mg/kg for E1. The remaining
compounds, E2, E3 and EE2, were below the limit of detection (i.e. 45 μg/kg) in all samples. These concentrations were similar to those that have been measured internationally. The dissipation of the
compounds 4NP, 4tOP, BPA and TCS was assessed over 32 weeks in the laboratory, following the addition of biosolids to a soil. The dissipation of 4NP, BPA and TCS followed a biphasic pattern which consisted of a dissipating fraction and a recalcitrant fraction. When the dissipation rates of the same four
compounds were assessed under field conditions, 4NP and 4tOP dissipated 10- to 20-times slower in the field and BPA dissipated 2.5-times slower compared to the laboratory-based dissipation rates. The compound…
Advisors/Committee Members: Warne, Michael St John (advisor), Smernik, Ronald Josef (advisor), Shareef, Ali (advisor), Kookana, Rai S. (advisor), School of Agriculture, Food and Wine (school).
Subjects/Keywords: pharmaceuticals; personal care products; endocrine disrupting compounds; biosolids
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Langdon, K. A. (2010). Environmental behaviour of pharmaceuticals, personal care products and endocrine disrupting compounds following land application of biosolids. (Thesis). University of Adelaide. Retrieved from http://hdl.handle.net/2440/65255
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Langdon, Kate Alison. “Environmental behaviour of pharmaceuticals, personal care products and endocrine disrupting compounds following land application of biosolids.” 2010. Thesis, University of Adelaide. Accessed January 27, 2021.
http://hdl.handle.net/2440/65255.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Langdon, Kate Alison. “Environmental behaviour of pharmaceuticals, personal care products and endocrine disrupting compounds following land application of biosolids.” 2010. Web. 27 Jan 2021.
Vancouver:
Langdon KA. Environmental behaviour of pharmaceuticals, personal care products and endocrine disrupting compounds following land application of biosolids. [Internet] [Thesis]. University of Adelaide; 2010. [cited 2021 Jan 27].
Available from: http://hdl.handle.net/2440/65255.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Langdon KA. Environmental behaviour of pharmaceuticals, personal care products and endocrine disrupting compounds following land application of biosolids. [Thesis]. University of Adelaide; 2010. Available from: http://hdl.handle.net/2440/65255
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Northeastern University
6.
Wurth, Renee.
Examination of the impact of environmental and dietary exposures on the health of Puerto Ricans.
Degree: PhD, Department of Health Sciences, 2017, Northeastern University
URL: http://hdl.handle.net/2047/D20285525
► Background: Puerto Ricans face health disparities when compared with both non-Hispanics whites as well as compared to other Hispanic subgroups. Although little research has been…
(more)
▼ Background: Puerto Ricans face health disparities when compared with both non-Hispanics whites as well as compared to other Hispanic subgroups. Although little research has been done specifically on this minority group, other research has shown that environmental and dietary exposures differ by ethic and minority groups and results in disparate health outcomes. We investigate how air pollution and diet impact health as well as the two health intermediates: urinary biomarkers and the gut microbiome.; Methods: A variety of methods were employed to access the relationships of air pollution, and diet and cognition, urinary phthalate metabolites and the composition of the gut microbiome, respectively. Linear models were used for association analyses using two prospective cohorts of Puerto Ricans, from northern Puerto Rico (Puerto Rico Testsite for Exploring Contamination Threats) and the greater Boston area (Boston Puerto Rican Health Study). From the latter we recruited participants, collected and processed stool samples to characterize their gut microbiome. Linear models and the analyses of the gut microbiome adjusted or stratified by demographic, socioeconomic and health variables.; Results: We observed that among our cohort of pregnant women in Puerto Rico, those who more frequently consumed milk, cheese, rice, bread, soft drink, fruit drinks, and dined out had higher levels of several urinary phthalate metabolites, while those who consumed more yogurt, egg and starch had lower levels across metabolites. Within the cohort of older Puerto Rican in Boston we found significant associations for the fine particulate (PM2.5) components, black carbon (BC) and nickel (Ni), across five cognitive domains. Additionally, within the subset of this cohort used for the pilot study, we found that the gut microbiome was dominated by the phylum Firmicutes, while having an average relative abundance of Bacteroidetes lower than that of other studies on both white and Hispanic populations.; Conclusions: Consistent significant associations were found for dietary items and urinary phthalate metabolites, BC and Ni and cognitive health, as well as the first characterization of the gut microbiome of elderly Puerto Ricans. These results further the research on health disparities for Puerto Ricans.
Subjects/Keywords: air pollution; endocrine disrupting compounds; health disparities; microbiome; nutrition; Puerto Ricans
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Wurth, R. (2017). Examination of the impact of environmental and dietary exposures on the health of Puerto Ricans. (Doctoral Dissertation). Northeastern University. Retrieved from http://hdl.handle.net/2047/D20285525
Chicago Manual of Style (16th Edition):
Wurth, Renee. “Examination of the impact of environmental and dietary exposures on the health of Puerto Ricans.” 2017. Doctoral Dissertation, Northeastern University. Accessed January 27, 2021.
http://hdl.handle.net/2047/D20285525.
MLA Handbook (7th Edition):
Wurth, Renee. “Examination of the impact of environmental and dietary exposures on the health of Puerto Ricans.” 2017. Web. 27 Jan 2021.
Vancouver:
Wurth R. Examination of the impact of environmental and dietary exposures on the health of Puerto Ricans. [Internet] [Doctoral dissertation]. Northeastern University; 2017. [cited 2021 Jan 27].
Available from: http://hdl.handle.net/2047/D20285525.
Council of Science Editors:
Wurth R. Examination of the impact of environmental and dietary exposures on the health of Puerto Ricans. [Doctoral Dissertation]. Northeastern University; 2017. Available from: http://hdl.handle.net/2047/D20285525

University of Manitoba
7.
Yang, Wenbo.
Investigation of endocrine disrupting compounds in membrane bioreactor and UV processes.
Degree: Biosystems Engineering, 2010, University of Manitoba
URL: http://hdl.handle.net/1993/3855
► Endocrine disrupting compounds (EDCs) in the environment have recently emerged as a major issue in Canada and around the globe. The primary objective of this…
(more)
▼ Endocrine disrupting compounds (EDCs) in the environment have recently emerged as a major issue in Canada and around the globe. The primary objective of this thesis was to investigate the fate of EDCs in two wastewater treatment processes, membrane bioreactors (MBRs) and ultraviolet (UV) disinfection. Two submerged MBR systems using hollow fiber membranes from two membrane manufacturers were tested. The results from a bench-scale and a pilot scale MBR for the treatment of swine wastewater with high concentration of EDCs showed that over 94% of the estrogenic activity (EA) in the influent was reduced through the MBR process. Biological degradation was the dominant removal mechanism for the removal of EDCs in MBRs. Over 85% of the influent EA was reduced by biodegradation through the MBR process. The other MBR system was built to study the removal mechanisms of two estrogens in a hybrid MBR with the addition of powdered activated carbon (PAC). The effects of PAC dosing on MBR overall performance was studied as well. It was found that PAC dosing could increase the removal rates of 17β-estradiol (E2) and 17α-ethinylestradiol (EE2) by 3.4% and 15.8%, respectively and result in a slower rate of trans-membrane pressure (TMP) increase during MBR operation, which could significantly reduce the operating cost for membrane cleaning and/or replacement. The operating cost for PAC dosing could be offset by the benefit achieved from reducing the cost for membrane maintenance. The slower rate of TMP increase in the PAC-MBR was associated with the lower concentrations of soluble extracellular polymeric substances and colloidal organic
compounds in the PAC-MBR sludge.
The degradation kinetics of three estrogens, estrone (E1), E2, and EE2 in de-ionized water by UV irradiation was studied. The experimental results showed both the apparent concentrations and overall EA of all three investigated estrogens in water decreased with direct UV irradiation. To further study the impact of UV on the overall EA of wastewater, the EA of pre-UV and post-UV samples from five wastewater treatment plants were measured in both liquid and solid phase by Yeast Estrogen Screen assay. It was found that the EA of wastewater decreased after UV disinfection in three of the investigated plants whereas it increased in the other two plants. This observation needs to be further studied because it might have significant impacts on the application of UV systems for wastewater disinfection.
Advisors/Committee Members: Cicek, Nazim (Biosystems Engineering) (supervisor), Mann, Danny (Biosystems Engineering).
Subjects/Keywords: Endocrine disrupting compounds; Membrane bioreactor; UV; Wastewater treatment; YES assay
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Yang, W. (2010). Investigation of endocrine disrupting compounds in membrane bioreactor and UV processes. (Thesis). University of Manitoba. Retrieved from http://hdl.handle.net/1993/3855
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Yang, Wenbo. “Investigation of endocrine disrupting compounds in membrane bioreactor and UV processes.” 2010. Thesis, University of Manitoba. Accessed January 27, 2021.
http://hdl.handle.net/1993/3855.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Yang, Wenbo. “Investigation of endocrine disrupting compounds in membrane bioreactor and UV processes.” 2010. Web. 27 Jan 2021.
Vancouver:
Yang W. Investigation of endocrine disrupting compounds in membrane bioreactor and UV processes. [Internet] [Thesis]. University of Manitoba; 2010. [cited 2021 Jan 27].
Available from: http://hdl.handle.net/1993/3855.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Yang W. Investigation of endocrine disrupting compounds in membrane bioreactor and UV processes. [Thesis]. University of Manitoba; 2010. Available from: http://hdl.handle.net/1993/3855
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of the Western Cape
8.
Abuaniza, Zaroug A.M.
Effects of green, black and rooibos tea, coffee and buchu on testosterone production by mouse testicular cultures
.
Degree: 2013, University of the Western Cape
URL: http://hdl.handle.net/11394/4584
► Modulation of the male reproductive system occurs as a result of exposure to endocrine disrupting compounds (EDCs) in different life stages. The effects of EDCs…
(more)
▼ Modulation of the male reproductive system occurs as a result of exposure to
endocrine disrupting compounds (EDCs) in different life stages. The effects of EDCs on the male reproductive system include infertility, decreased sperm count, function and morphology, abnormal development of secondary sex characteristics, reproductive function and sexual behavior, as well as decreased libido. Phytochemicals are naturally occurring, biologically active chemical
compounds in plants. They are divided into different groups. Isoflavonoids and lignans, are the two major groups of phytoestrogens. Phytoestrogens of teas, coffee and buchu have many beneficial effects on body systems such as antimutagenic, antidiabetic, anti-inflammatory, antibacterial and antiviral properties. They also elicit many adverse events, for example, heavy consumption of green and black tea may cause liver damage and added unwanted effects when combined with other herbal beverages. Chronic heavy consumption of coffee is positively correlated to acute myocardial infarction and can elevate serum cholesterol levels. Rooibos tea decreases steroidogenesis by steroid secreting cell lines.This study investigated the effects of these beverages on the male reproductive system, using a minced testes method for determination of cell viability and hormone (testosterone) production. The first objective of this study was to optimize protein supplement for in vitro testosterone production using human serum albumin (HSA) and foetal bovine serum (FBS). Testicular cultures were prepared and exposed overnight to different concentrations of both sera and then incubated for 4 hours with or without luteinizing hormone (LH). The results showed that addition of protein supplements (HSA or FBS) did not have a significant effect on testosterone production. The second objective of this study was to investigate the effects of green tea, black tea, rooibos tea, coffee and buchu on cell viability of testicular cultures. Cells were treated overnight with varying concentrations of the plant extracts followed by incubation with/without LH for 4 hours. The effects of the plant beverages on cellular protein production were determined by the Bradford assay. The results showed that treatment of cells with varying concentrations of the plant extracts (with/without LH-treatment) had no significant effect on total cellular protein. The third objective of this study was to investigate the effects of black, green and rooibos teas, coffee and buchu on testosterone production by testicular cultures. The results obtained from these experiments showed that rooibos tea and buchu did not affect testosterone production in the presence or absence of LH. The results also indicated that green tea, black tea and coffee inhibited testosterone production by mouse testis cultures in the presence of LH, but not in the absence of LH. Black tea was the most potent inhibitor of testosterone synthesis by mouse testis cultures (IC50= 48 μg/ml), followed by coffee (IC50= 64 μg/ml) and green tea (IC50= 173 μg/ml).…
Advisors/Committee Members: Pool, Edmund J (advisor).
Subjects/Keywords: Male reproductive system;
Testosterone production;
Rooibos tea;
Endocrine disrupting compounds
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Abuaniza, Z. A. M. (2013). Effects of green, black and rooibos tea, coffee and buchu on testosterone production by mouse testicular cultures
. (Thesis). University of the Western Cape. Retrieved from http://hdl.handle.net/11394/4584
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Abuaniza, Zaroug A M. “Effects of green, black and rooibos tea, coffee and buchu on testosterone production by mouse testicular cultures
.” 2013. Thesis, University of the Western Cape. Accessed January 27, 2021.
http://hdl.handle.net/11394/4584.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Abuaniza, Zaroug A M. “Effects of green, black and rooibos tea, coffee and buchu on testosterone production by mouse testicular cultures
.” 2013. Web. 27 Jan 2021.
Vancouver:
Abuaniza ZAM. Effects of green, black and rooibos tea, coffee and buchu on testosterone production by mouse testicular cultures
. [Internet] [Thesis]. University of the Western Cape; 2013. [cited 2021 Jan 27].
Available from: http://hdl.handle.net/11394/4584.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Abuaniza ZAM. Effects of green, black and rooibos tea, coffee and buchu on testosterone production by mouse testicular cultures
. [Thesis]. University of the Western Cape; 2013. Available from: http://hdl.handle.net/11394/4584
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Minnesota
9.
Kadlec, Sarah.
Evaluation of testicular oocytes and gonadal development in smallmouth bass (Micropterus dolomieu) under presumed and known exposure to estrogenic compounds.
Degree: PhD, Integrated Biosciences, 2017, University of Minnesota
URL: http://hdl.handle.net/11299/198386
► Testicular oocytes (TOs), a form of gonadal intersex, have been found in black basses (Micropterus spp.) from many locations in North America. The presence of…
(more)
▼ Testicular oocytes (TOs), a form of gonadal intersex, have been found in black basses (Micropterus spp.) from many locations in North America. The presence of TOs is often assumed to imply exposure to estrogenic endocrine disrupting compounds (EDCs), however, a definitive causal relationship has yet to be established, and TO prevalence is not consistently low in fish from areas lacking evident EDC sources. This could suggest unknown or unidentified EDC sources, or that TOs can be stimulated by other stressors, or that they arise spontaneously during normal development. The goal of this dissertation research was to improve our ability to interpret observations of TOs in smallmouth bass (M. dolomieu) in particular, with approaches that are applicable to any other species. These approaches included statistical analysis of TO occurrence in wild populations where estrogenic exposure is more and less likely, and laboratory studies to characterize the early gonadal development in smallmouth bass, both in the presence and absence of exogenous estrogen. TO occurrence in smallmouth bass was assessed in eight watersheds in Northeastern Minnesota watersheds with differing degrees of human development, and hence, likelihood of EDC exposure. Testicular tissues from mature fish were evaluated using a semi-quantitative method that estimated TO density, normalized by cross-sectional area. TO prevalence and density among populations from more developed watersheds were higher than in populations from less developed watersheds. However, TO prevalence was unexpectedly high and variable (7-43%) in some populations from less developed watersheds, and only weak evidence was found for a relationship between TO density and watershed development, suggesting alternative or more complex explanations for TO presence in smallmouth bass. To characterize early gonadal development in smallmouth bass, both in the presence and absence of estrogen, swim-up fry were exposed to control water or the potent model estrogen, 17α-ethinylestradiol (EE2), for 90 days, and reared for another 90 days in clean water. Development of gonadal tissue was assessed at 11 time points using standard histology methods. Ovarian differentiation was observed in 50% of control fish by test day 49, and testicular differentiation occurred by day 92. Among EE2-exposed groups, ovarian phenotypes were observed in 83% of fish by day 49, and in 98% of fish between days 92 and 180, indicating that EE2 can cause complete, and likely permanent, sex reversal in smallmouth bass. Among the EE2-exposed fish that developed ovaries between days 92 and 180, 38% had abnormal characteristics, suggesting that ovaries in sex reversed males can be distinguished from ovaries in genetic females. In a second laboratory study, smallmouth bass gonadal development was assessed during early life stage exposure across a range of concentrations of EE2, including environmentally realistic concentrations. 97% of fish exposed to 4.3 ng/L EE2 (mean measured concentration) had ovaries on test days…
Subjects/Keywords: Ecotoxicology; Endocrine disrupting compounds; Ethinylestradiol; Gonadal development; Sexual differentiation; Smallmouth bass
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Kadlec, S. (2017). Evaluation of testicular oocytes and gonadal development in smallmouth bass (Micropterus dolomieu) under presumed and known exposure to estrogenic compounds. (Doctoral Dissertation). University of Minnesota. Retrieved from http://hdl.handle.net/11299/198386
Chicago Manual of Style (16th Edition):
Kadlec, Sarah. “Evaluation of testicular oocytes and gonadal development in smallmouth bass (Micropterus dolomieu) under presumed and known exposure to estrogenic compounds.” 2017. Doctoral Dissertation, University of Minnesota. Accessed January 27, 2021.
http://hdl.handle.net/11299/198386.
MLA Handbook (7th Edition):
Kadlec, Sarah. “Evaluation of testicular oocytes and gonadal development in smallmouth bass (Micropterus dolomieu) under presumed and known exposure to estrogenic compounds.” 2017. Web. 27 Jan 2021.
Vancouver:
Kadlec S. Evaluation of testicular oocytes and gonadal development in smallmouth bass (Micropterus dolomieu) under presumed and known exposure to estrogenic compounds. [Internet] [Doctoral dissertation]. University of Minnesota; 2017. [cited 2021 Jan 27].
Available from: http://hdl.handle.net/11299/198386.
Council of Science Editors:
Kadlec S. Evaluation of testicular oocytes and gonadal development in smallmouth bass (Micropterus dolomieu) under presumed and known exposure to estrogenic compounds. [Doctoral Dissertation]. University of Minnesota; 2017. Available from: http://hdl.handle.net/11299/198386

University of Western Ontario
10.
Atisha, Ambareen.
Identification, Quantification and Removal of Pharmaceuticals and Endocrine Disrupting Compounds from Water Using Customized PDMS Membrane.
Degree: 2017, University of Western Ontario
URL: https://ir.lib.uwo.ca/etd/4370
► This study concentrates on the identification and quantification of three pharmaceutical compounds (ibuprofen, naproxen and diclofenac) and an endocrine disrupting compound (17α-ethinylestradiol) in wastewater effluents…
(more)
▼ This study concentrates on the identification and quantification of three pharmaceutical compounds (ibuprofen, naproxen and diclofenac) and an endocrine disrupting compound (17α-ethinylestradiol) in wastewater effluents collected from Adelaide Wastewater Treatment Plant and Greenway Pollution Control Plant, London, ON, Canada. For sample preparation, both solid-phase extraction and liquid-liquid extraction techniques were followed and GC-FID and LC-MS were used for sample analysis. Although the target pharmaceuticals were present in the wastewater samples at concentrations in a range of 0.29-8.98 µ/L, 17α-ethinylestradiol was not detected.
For eradicating or removing the above-mentioned organic compounds from water, organic solvent nanofiltration (OSNF) membrane was used in this study. Different types of OSNF membranes were prepared where commercially available PTFE ultrafiltration membrane as well as laboratory-made polysulfone ultrafiltration membranes served as the base supports, and poly (dimethylsiloxane) as the thin active layer. A thin film composite membrane was also prepared using a base support made of a mixture of polysulfone and multi-walled carbon nanotubes and a thin active layer top constituted from interfacial polymerization between m-phenylenediamine and trymesoyl chloride. For membrane characterization, Scanning Electron Microscopy (SEM) and Atomic Force Microscoopy (AFM) were performed. The performance of the membranes was studied by monitoring permeability along with the removal capacity using a dead-end filtration system, under a pressure range of 5~30 bars. A commercially available polyimide membrane, DuraMem, was exploited to compare the membrane performance. The 2.5% PTFE/PDMS (RTV 615) membrane showed the highest performance by removing 95~97% 17α- ethinylestradiol, 70% ibuprofen, 65% naproxen and 65% diclofenac. Hansen’s Solubility Parameter theory was adopted to explain the removal mechanism of pharmaceutical compounds, while size exclusion theory explained the removal of the synthetic estrogen by OSNF.
Subjects/Keywords: Wastewater effluent; pharmaceutically active compounds; endocrine disrupting compounds; organic solvent nanofiltration; PDMS; polyimide; Environmental Engineering
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Atisha, A. (2017). Identification, Quantification and Removal of Pharmaceuticals and Endocrine Disrupting Compounds from Water Using Customized PDMS Membrane. (Thesis). University of Western Ontario. Retrieved from https://ir.lib.uwo.ca/etd/4370
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Atisha, Ambareen. “Identification, Quantification and Removal of Pharmaceuticals and Endocrine Disrupting Compounds from Water Using Customized PDMS Membrane.” 2017. Thesis, University of Western Ontario. Accessed January 27, 2021.
https://ir.lib.uwo.ca/etd/4370.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Atisha, Ambareen. “Identification, Quantification and Removal of Pharmaceuticals and Endocrine Disrupting Compounds from Water Using Customized PDMS Membrane.” 2017. Web. 27 Jan 2021.
Vancouver:
Atisha A. Identification, Quantification and Removal of Pharmaceuticals and Endocrine Disrupting Compounds from Water Using Customized PDMS Membrane. [Internet] [Thesis]. University of Western Ontario; 2017. [cited 2021 Jan 27].
Available from: https://ir.lib.uwo.ca/etd/4370.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Atisha A. Identification, Quantification and Removal of Pharmaceuticals and Endocrine Disrupting Compounds from Water Using Customized PDMS Membrane. [Thesis]. University of Western Ontario; 2017. Available from: https://ir.lib.uwo.ca/etd/4370
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

NSYSU
11.
Zen, Yi-peng.
Treatment of Endocrine Disrupting Chemicals (EDCs) by Constructed Wetlands.
Degree: Master, Marine Environment and Engineering, 2010, NSYSU
URL: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0715110-153809
► Alkylphenol polyethoxylates (APEOs), a class of nonionic surfactants, have been widely used for industrial, agricultural and household applications. The biodegradation metabolites of APEOs, such as…
(more)
▼ Alkylphenol polyethoxylates (APEOs), a class of nonionic surfactants, have been widely used for industrial, agricultural and household applications. The biodegradation metabolites of APEOs, such as nonylphenol and octylphenol, are more persistent and known to disrupt
endocrine function in wildlife and human. These
compounds are also recognized as
endocrine disrupting chemicals (EDCs). The objectives of this study were to investigate the distribution and removal efficiencies of EDCs, including nonylphenol diethoxylates (NP2EO), nonylphenol monoethoxylates (NP1EO), nonylphenol (NP) and octylphenol (OP), of wastewater treated by the constructed wetland systems along the Dahan River and around the Dapeng Bay, respectively. In addition, the method of risk quotient was used to evaluate the potential ecological risk of APEOs to aquatic organisms in current study.
The water samples collected from 32 sampling sites in the Dapeng Bay National Scenic Area including Datan, Pengcun and Linbain right bank constructed wetlands. The samples were then concentrated by solid phase extraction, and analyzed for target
compounds by HPLC/fluorescence. According to the results, nonylphenol diethoxylates, nonylphenol monoethoxylates, nonylphenol and octylphenol were found approximately equal to 29.9, 47.3, 20.5 and 57.7 %, respectively of the samples from three constructed wetlands with concentrations ranged from <3.3 to 968.7, <3.3 to 226.5, <1.3 to 238.4 and <1.0 to 1458.7 ng/L, respectively. Temporal variation of APEOs showed a decreasing in the order of summerï¼springï¼winterï¼autumn. The removal efficiencies of APEOs in these constructed wetlands showed a decreasing order of Datan wetlandï¼Pengcun wetlandï¼Linbain right bank wetland.
In addition, the samples collected from 18 sampling sites from the constructed wetlands along the riparian of Dahan River including Daniaopi, Hsin-Hai Bridge Phases I and II constructed wetlands. According to the results, nonylphenol diethoxylates, nonylphenol monoethoxylates, nonylphenol and octylphenol were found approximately equal to 91.9ã84.8ã17.1 and 73.7 %, respectively of samples collected from three constructed wetlands with concentrations ranged from <3.3 to 11191.5, <3.3 to 6069.0, <1.3 to 671.0 and <1.0 to 5581.9 ng/L, respectively. The removal potential of APEOs in these constructed wetlands showed a decreasing order of Hsin-Hai Bridge Phases IIï¼Daniaopiï¼Hsin-Hai Bridge Phases I constructed wetland.
Regarding the ecological assessment in this research, the calculated risk quotients were up to 30 times higher in the constructed wetland systems of Dahan River than those in the Dapeng Bay National Scenic Area, indicating that the existing concentrations of these EDCs in wetland systems might cause potential ecological risks to aquatic organisms. Furthermore, the decreasing risk quotient from influent to effluent indicating the capabilities of treating alkylphenolic
compounds in these constructed wetlands.
Advisors/Committee Members: Chi-Ying Hsieh (committee member), Chih-Ming Kao (chair), Wen-Chien Kuo (chair), Lei Yang (committee member).
Subjects/Keywords: Ecological Risk Assessment; Constructed Wetland; Environment Hormone; Alkylphenolic Compounds; Endocrine Disrupting Chemicals
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Zen, Y. (2010). Treatment of Endocrine Disrupting Chemicals (EDCs) by Constructed Wetlands. (Thesis). NSYSU. Retrieved from http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0715110-153809
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Zen, Yi-peng. “Treatment of Endocrine Disrupting Chemicals (EDCs) by Constructed Wetlands.” 2010. Thesis, NSYSU. Accessed January 27, 2021.
http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0715110-153809.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Zen, Yi-peng. “Treatment of Endocrine Disrupting Chemicals (EDCs) by Constructed Wetlands.” 2010. Web. 27 Jan 2021.
Vancouver:
Zen Y. Treatment of Endocrine Disrupting Chemicals (EDCs) by Constructed Wetlands. [Internet] [Thesis]. NSYSU; 2010. [cited 2021 Jan 27].
Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0715110-153809.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Zen Y. Treatment of Endocrine Disrupting Chemicals (EDCs) by Constructed Wetlands. [Thesis]. NSYSU; 2010. Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0715110-153809
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

NSYSU
12.
Yu, Bo-Ya.
Assessment of Estrogenic Activity in a Constructed Wetland Using Bioassay.
Degree: Master, Marine Environment and Engineering, 2014, NSYSU
URL: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0020114-125635
► The first objective of this study was to investigate the removal efficiency of the endocrine disrupting chemicals(EDCs), including phenolic compounds such as nonylphenol(NP), octylphenol(OP) and…
(more)
▼ The first objective of this study was to investigate the removal efficiency of the
endocrine disrupting chemicals(EDCs), including phenolic
compounds such as nonylphenol(NP), octylphenol(OP) and bisphenol A(BPA), and natural and synthetic chemicals such as estrone(E1), 17β-estradiol(E2), estriol(E3), diethylstilbestrol(DES) and 17α-ethinylestradiol(EE2) of wastewater treated by the constructed wetland from the Wan-Dan embankment. The second objective was to assess the estrogenic activity with different treatment units using the T47D-KBluc bioassay.
According to the T47D-KBluc assay, the estrogenicities in influent(In), grit chamber(GC), pre-aeration tank (AT), the contact aeration tank(CAT), aquatic plants area (PA) and effluent(Eff) were ranged from 1.18 to 30.4, 0.85 to 27.74, 0.46 to 3.32, 0.53 to 6.48, 0.48 to 13.44 and 0.52 to 21.16ng 17β-estradiol(E2) equivalents/L. The results of the different flows from the constructed wetland, 100CMD, 200CMD, 350CMD and 500CMD showed the mean removal efficiency of estrogenic activity, 64%, 42%, 36% and 31%, respectively.
In chemical analysis, the samples were pre-concentrated by solid phase extraction, and analyzed for target
compounds by LC-MS/MS method. According to the results, estrone, estradiol, ethynyl estradiol and diethylstilbestrol were not detected throughout the study period. The detection frequency of estriol, nonylphenol, octylphenol and bisphenol A were approximately 16%, 3%, 21% and 1%, respectively. The removal efficiency of estriol and octylphenol, showed was larger than 99% and 37%,respectively. Nonylphenol canât be removed in the system. Bisphenol A detected only in one sample located in the aquatic plants area.
Comparison of to the chemical analysis and bioassay, the concentration of estrogenic activity ranged from ND to 0.46ng / L and 0.48 to 30.3ng / L, respectively. Bioassay could be used to detect known and unknown estrogenic
compounds, as a rapid and effective detection method.
Advisors/Committee Members: Wen-Chen Kuo (chair), Jimmy C. M. Kao (chair), Lei Yang (committee member), Chi-Ying Hsieh (committee member).
Subjects/Keywords: Estrogenic Compounds; T47B-KBluc Bioassay; Constructed Wetland; Endocrine Disrupting Chemicals; Estrogenic Activity
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Yu, B. (2014). Assessment of Estrogenic Activity in a Constructed Wetland Using Bioassay. (Thesis). NSYSU. Retrieved from http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0020114-125635
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Yu, Bo-Ya. “Assessment of Estrogenic Activity in a Constructed Wetland Using Bioassay.” 2014. Thesis, NSYSU. Accessed January 27, 2021.
http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0020114-125635.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Yu, Bo-Ya. “Assessment of Estrogenic Activity in a Constructed Wetland Using Bioassay.” 2014. Web. 27 Jan 2021.
Vancouver:
Yu B. Assessment of Estrogenic Activity in a Constructed Wetland Using Bioassay. [Internet] [Thesis]. NSYSU; 2014. [cited 2021 Jan 27].
Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0020114-125635.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Yu B. Assessment of Estrogenic Activity in a Constructed Wetland Using Bioassay. [Thesis]. NSYSU; 2014. Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0020114-125635
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Tulane University
13.
Srisawat, Ponsawat.
Deactivation of Endocrine Disrupting Compounds in Wastewater by Ferrate(VI) Oxidant.
Degree: PhD, 2013, Tulane University
URL: https://digitallibrary.tulane.edu/islandora/object/tulane:26625
► In recent years exposure to endocrine-disrupting chemicals (EDCs) in humans and wildlife has become an increasing concern. These compounds have been found ubiquitously in the…
(more)
▼ In recent years exposure to
endocrine-
disrupting chemicals (EDCs) in humans and wildlife has become an increasing concern. These
compounds have been found ubiquitously in the environment and are suspected to induce adverse effects on the health of aquatic organisms. The results of health effects due to EDCs are clearly presented in many aquatic organisms, such as the feminization of male fish and a near extinction of some species. No clear effects on human health have been documented at this time. The major sources of these contaminants in the environment are discharges from wastewater treatment plants (WWTP) and diffuse pollution. Conventional wastewater treatment processes are not designed to remove such emerging pollutants and removal efficiency depends on many factors, including treatment technology and pollutant species. Passage through WWTPs and changes due to treatment technologies lead to detection of minute concentrations of EDCs in water downstream from discharge points. In New Orleans, Louisiana, discharge from its East Bank WWTP is being considered for potential reuse for wetland restoration. Therefore, effluents must be treated adequately to prevent adverse effects on the natural biota. Since effluents from wastewater treatment plants using conventional technologies may prove potentially unsafe for the environment due to the presence of EDCs, improved and/or new treatment processes for removal of these contaminants are needed. Ferrate (Fe+6) is known as an alternative oxidant for the treatment of wastewater that can be used as an oxidizing, disinfectant, and/or coagulating agent. Because of its redox potential, ferrate has been used as a disinfection agent and has been reported as a tool for enhanced treatment to remove many micropollutants without producing undesirable disinfection byproducts in contrast to other disinfection processes. Recent research has noted the ability of ferrate to deactivate a wide range of EDCs present in wastewater effluents. The negative effect of effluent's soluble organic matter on ferrate has been reported and higher doses of ferrate may be needed to obtain desired effluent quality. This study found that aerobic biological treatment processes reduce more than half of EDCs in wastewater and that free chlorine disinfection increases estrogenic activity in discharged effluent. Higher organic content in wastewater results in increased ferrate demand. The optimum ferrate dosage to deactivate EDCs in lab scale is 6 ppm, and a dosage of 8 ppm is possibly the operational optimum dose. pH neutralization by concentrated sulfuric acid was not found to affect EDCs deactivation efficiency by ferrate when added at the end of designed contact time. Ferrate was observed to have a high oxidation rate in the first10 minutes after application into wastewater and then degraded to other iron states, such as iron III. Higher oxidation rates can be obtained when more organics are present in wastewater as TOC. Higher dosages required longer oxidation reaction times. Ferrate was observed to…
Advisors/Committee Members: Reimers, Robert (Thesis advisor).
Subjects/Keywords: Ferrate; Endocrine disrupting compounds; Deactivation; School of Public Health & Tropical Medicine; Environmental Health Sciences; Ph.D
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Srisawat, P. (2013). Deactivation of Endocrine Disrupting Compounds in Wastewater by Ferrate(VI) Oxidant. (Doctoral Dissertation). Tulane University. Retrieved from https://digitallibrary.tulane.edu/islandora/object/tulane:26625
Chicago Manual of Style (16th Edition):
Srisawat, Ponsawat. “Deactivation of Endocrine Disrupting Compounds in Wastewater by Ferrate(VI) Oxidant.” 2013. Doctoral Dissertation, Tulane University. Accessed January 27, 2021.
https://digitallibrary.tulane.edu/islandora/object/tulane:26625.
MLA Handbook (7th Edition):
Srisawat, Ponsawat. “Deactivation of Endocrine Disrupting Compounds in Wastewater by Ferrate(VI) Oxidant.” 2013. Web. 27 Jan 2021.
Vancouver:
Srisawat P. Deactivation of Endocrine Disrupting Compounds in Wastewater by Ferrate(VI) Oxidant. [Internet] [Doctoral dissertation]. Tulane University; 2013. [cited 2021 Jan 27].
Available from: https://digitallibrary.tulane.edu/islandora/object/tulane:26625.
Council of Science Editors:
Srisawat P. Deactivation of Endocrine Disrupting Compounds in Wastewater by Ferrate(VI) Oxidant. [Doctoral Dissertation]. Tulane University; 2013. Available from: https://digitallibrary.tulane.edu/islandora/object/tulane:26625

University of Toronto
14.
Diemert, Sabrina Anne.
The Impact of Coagulation on Endocrine Disrupting Compounds, Pharmaceutically Active Compounds and Natural Organic Matter.
Degree: 2012, University of Toronto
URL: http://hdl.handle.net/1807/32462
► Previous research indicates that pharmaceutically active compounds (PhACs) and endocrine-disrupting compounds (EDCs) are poorly removed during conventional drinking water treatment processes including coagulation; however, removal…
(more)
▼ Previous research indicates that pharmaceutically active compounds (PhACs) and endocrine-disrupting compounds (EDCs) are poorly removed during conventional drinking water treatment processes including coagulation; however, removal efficiency increases in the presence of natural organic matter (NOM). Therefore, this project investigates the link between various NOM types with EDC/PhAC removal. Bench-scale coagulation tests were conducted on three different source waters spiked with environmentally relevant levels (nominally 1000 ng/L) of EDCs/PhACs. Two different coagulants were used: polyaluminum chloride (PACl) and aluminum sulphate (alum). NOM was characterized using size exclusion liquid chromatography-organic carbon detection (LC-OCD).
Results for Lake Ontario, Otonabee and Grand River water indicate that certain EDCs/PhACs are significantly removed during coagulation while others increase in concentration. Concurrently, particular NOM fractions (biopolymers and humic substances) are also being removed. Solvents used for EDC/PhAC spiking (acetone and acetonitrile) did not affect coagulation, but contributed to low molecular weight neutral and hydrophobic NOM fractions.
MAST
Advisors/Committee Members: Andrews, Robert C., Civil Engineering.
Subjects/Keywords: Water treatment; Natural organic matter; Endocrine disrupting compounds; Pharmaceuticals; Coagulation; LC-OCD; 0775
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Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
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APA (6th Edition):
Diemert, S. A. (2012). The Impact of Coagulation on Endocrine Disrupting Compounds, Pharmaceutically Active Compounds and Natural Organic Matter. (Masters Thesis). University of Toronto. Retrieved from http://hdl.handle.net/1807/32462
Chicago Manual of Style (16th Edition):
Diemert, Sabrina Anne. “The Impact of Coagulation on Endocrine Disrupting Compounds, Pharmaceutically Active Compounds and Natural Organic Matter.” 2012. Masters Thesis, University of Toronto. Accessed January 27, 2021.
http://hdl.handle.net/1807/32462.
MLA Handbook (7th Edition):
Diemert, Sabrina Anne. “The Impact of Coagulation on Endocrine Disrupting Compounds, Pharmaceutically Active Compounds and Natural Organic Matter.” 2012. Web. 27 Jan 2021.
Vancouver:
Diemert SA. The Impact of Coagulation on Endocrine Disrupting Compounds, Pharmaceutically Active Compounds and Natural Organic Matter. [Internet] [Masters thesis]. University of Toronto; 2012. [cited 2021 Jan 27].
Available from: http://hdl.handle.net/1807/32462.
Council of Science Editors:
Diemert SA. The Impact of Coagulation on Endocrine Disrupting Compounds, Pharmaceutically Active Compounds and Natural Organic Matter. [Masters Thesis]. University of Toronto; 2012. Available from: http://hdl.handle.net/1807/32462

Hong Kong University of Science and Technology
15.
Mak, Shuk Fong.
Adsorption of endocrine disrupting compounds.
Degree: 2011, Hong Kong University of Science and Technology
URL: http://repository.ust.hk/ir/Record/1783.1-7271
;
https://doi.org/10.14711/thesis-b1156465
;
http://repository.ust.hk/ir/bitstream/1783.1-7271/1/th_redirect.html
► Endocrine disrupting compounds, which are the compounds having the ability to interfere with the hormonal system, have drawn growing attentions worldwide over the last decades,…
(more)
▼ Endocrine disrupting compounds, which are the compounds having the ability to interfere with the hormonal system, have drawn growing attentions worldwide over the last decades, owing to their frequent detections in surface and ground water and their potential environmental and health hazards. Adsorption is one of the promising methods for the removal of EDCs in water. The purpose of this research is to evaluate the adsorption performance of various commercial adsorbents (activated carbon (AC), alumina (Al2O3) and hydrotalcite (HT)) and new adsorbents (MCM-41 and mesoporous carbon (MC)) toward different endocrine disrupting compounds (EDCs). Six EDCs, namely caffeine (CF), carbamazepine (CBZ), diclofenac (DFS), estradiol (EE2), phthalates (KHP) and nonylphenol (NP), were selected to be the model pollutants. Detailed characterization tests of each adsorbent were conducted. Adsorption performances of each adsorbent were evaluated through adsorption kinetics, equilibria and pH effect on the partition coefficient (Kd) of six EDCs in the single component system. The results of the adsorption kinetics and adsorption equilibria were modeled by kinetic equations (pseudo-first and pseudo-second order equation) and isotherm model (Langmuir isotherm model and Freundlich isotherm model) respectively. Those results on AC and HT were correlated to the hydrophobicity (logKow) and ease of ionization (pKa) of EDCs. More studies were done on AC. The binary component adsorption studies were presented with the modeling with Extended Langmuir isotherm and Ideal Adsorbed Solution (IAS) theory. Adsorption performance of EDC degradates on AC was demonstrated by the adsorption kinetics and equilibria study. Synergetic effect of adsorption of AC and ozonation were also studied and found that AC exerted the positive effect to increase the rate of ozonation. Adsorption thermodynamics on AC was also evaluated.
Subjects/Keywords: Water – Purification – Adsorption
; Water – Purification – Organic compounds removal – By-products
; Endocrine disrupting chemicals
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Mak, S. F. (2011). Adsorption of endocrine disrupting compounds. (Thesis). Hong Kong University of Science and Technology. Retrieved from http://repository.ust.hk/ir/Record/1783.1-7271 ; https://doi.org/10.14711/thesis-b1156465 ; http://repository.ust.hk/ir/bitstream/1783.1-7271/1/th_redirect.html
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Mak, Shuk Fong. “Adsorption of endocrine disrupting compounds.” 2011. Thesis, Hong Kong University of Science and Technology. Accessed January 27, 2021.
http://repository.ust.hk/ir/Record/1783.1-7271 ; https://doi.org/10.14711/thesis-b1156465 ; http://repository.ust.hk/ir/bitstream/1783.1-7271/1/th_redirect.html.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Mak, Shuk Fong. “Adsorption of endocrine disrupting compounds.” 2011. Web. 27 Jan 2021.
Vancouver:
Mak SF. Adsorption of endocrine disrupting compounds. [Internet] [Thesis]. Hong Kong University of Science and Technology; 2011. [cited 2021 Jan 27].
Available from: http://repository.ust.hk/ir/Record/1783.1-7271 ; https://doi.org/10.14711/thesis-b1156465 ; http://repository.ust.hk/ir/bitstream/1783.1-7271/1/th_redirect.html.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Mak SF. Adsorption of endocrine disrupting compounds. [Thesis]. Hong Kong University of Science and Technology; 2011. Available from: http://repository.ust.hk/ir/Record/1783.1-7271 ; https://doi.org/10.14711/thesis-b1156465 ; http://repository.ust.hk/ir/bitstream/1783.1-7271/1/th_redirect.html
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
16.
Mezghani-Chaari, Sawssan.
Effet de la pollution urbaine et industrielle sur le système endocrinien : évaluation des conséquences sur la reproduction de "Ruditapes decusatus" issue du golfe de Gabès (Tunisie) : Effect of urban and industrial pollution on the endocrine system : evaluation of the consequences on reproduction of "Ruditapes decussatus".
Degree: Docteur es, Physiologie et biologie des organismes - populations - interactions, 2017, Normandie; Université de Sfax (Tunisie)
URL: http://www.theses.fr/2017NORMLH25
► Notre étude a porté sur le diagnostic de la présence des perturbateurs endocriniens dans le golfe de Gabès (Tunisie), leurs effets sur la reproduction d’une…
(more)
▼ Notre étude a porté sur le diagnostic de la présence des perturbateurs endocriniens dans le golfe de Gabès (Tunisie), leurs effets sur la reproduction d’une espèce bioindicatrice de pollution, la palourde R. decussatus ainsi que leurs mécanismes d’action. Pour atteindre ces objectifs, nous avons fait appel à plusieurs outils méthodologiques, des expositions in vivo (effluents urbains, effluents industriels, 17β-œstradiol) et des prélèvements in situ afin d’évaluer le risque encouru par l’écosystème du golfe de Gabès tout entier en utilisant une approche multiparamétrique basée sur différents niveaux de l’organisation biologique (allant du niveau biochimique jusqu’au niveau populationnel). Nous avons mis en évidence la présence des composés reprotoxiques tout au long de la côte Sud-Est de la Tunisie. Les résultats obtenus ont révélé une corrélation entre la contamination chimique (cadmium, activités œstrogéniques et androgéniques au niveau du sédiment) et certains paramètres biologiques liés à la reproduction (diamètre ovocytaire, vitellogénine, glycogène) et un site très divergent de tous les autres sites (El hofra). Cette station d’El hofra semble être touchée par une perturbation endocrinienne liée probablement à une synergie entre la contamination par le Cd et la présence des composés à activité œstrogénique et androgénique dans le milieu. En parallèle à cette étude in situ, trois expérimentations au laboratoire ont été réalisées. Les résultats ont montré que les effluents de la station d’épuration de Sfax (cocktail de contaminants) sont capables d’affecter la reproduction de la palourde en induisant la synthèse de la vitellogénine et stimulant la reproduction chez les deux sexes. L’exposition des palourdes à un contaminant pur, le 17β-œstradiol, a révélé qu’il peut contribuer à expliquer les perturbations du cycle reproducteur observées dans l’expérience précédente. Cette hormone naturelle a un effet et sans doute un rôle dans la physiologie de la palourde. Dans le but d’étudier son mécanisme d’action via le récepteur aux œstrogènes (RE), nous avons cloné une partie de l’ADNc codant pour les RE. Cependant, l’analyse de la réponse transcriptionnelle n’a pas montré de changement significatif dans l'expression du gène aussi bien chez les mâles que chez les femelles suite à une exposition aux œstrogènes (17β-œstradiol, effluents urbains et industriels).
Our study aimed to assess the presence of endocrine disrupting compounds in the Gulf of Gabes area (Tunisia), their effects on the reproductive potential of the marine bivalve, Ruditapes decussatus as well as elucidating their mechanisms of action. To achieve these goals, several methodologies have been deployed, such as laboratory in vivo exposures (to urban or industrial effluents, estradiol), and in situ sampling to assess the risk of such substances on this ecosystem by using a multiparametric approach based on different levels of biological organization in clams (from biochemical level to the population level). We have demonstrated the presence of reprotoxic…
Advisors/Committee Members: Minier, Christophe (thesis director), Hamza-Chaffai, Amel (thesis director).
Subjects/Keywords: Ruditapes decussatus; Ruditapes decussatus; Endocrine disrupting compounds; Gulf of Gabes (Tunisia); Reproduction; Biomarkers
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Mezghani-Chaari, S. (2017). Effet de la pollution urbaine et industrielle sur le système endocrinien : évaluation des conséquences sur la reproduction de "Ruditapes decusatus" issue du golfe de Gabès (Tunisie) : Effect of urban and industrial pollution on the endocrine system : evaluation of the consequences on reproduction of "Ruditapes decussatus". (Doctoral Dissertation). Normandie; Université de Sfax (Tunisie). Retrieved from http://www.theses.fr/2017NORMLH25
Chicago Manual of Style (16th Edition):
Mezghani-Chaari, Sawssan. “Effet de la pollution urbaine et industrielle sur le système endocrinien : évaluation des conséquences sur la reproduction de "Ruditapes decusatus" issue du golfe de Gabès (Tunisie) : Effect of urban and industrial pollution on the endocrine system : evaluation of the consequences on reproduction of "Ruditapes decussatus".” 2017. Doctoral Dissertation, Normandie; Université de Sfax (Tunisie). Accessed January 27, 2021.
http://www.theses.fr/2017NORMLH25.
MLA Handbook (7th Edition):
Mezghani-Chaari, Sawssan. “Effet de la pollution urbaine et industrielle sur le système endocrinien : évaluation des conséquences sur la reproduction de "Ruditapes decusatus" issue du golfe de Gabès (Tunisie) : Effect of urban and industrial pollution on the endocrine system : evaluation of the consequences on reproduction of "Ruditapes decussatus".” 2017. Web. 27 Jan 2021.
Vancouver:
Mezghani-Chaari S. Effet de la pollution urbaine et industrielle sur le système endocrinien : évaluation des conséquences sur la reproduction de "Ruditapes decusatus" issue du golfe de Gabès (Tunisie) : Effect of urban and industrial pollution on the endocrine system : evaluation of the consequences on reproduction of "Ruditapes decussatus". [Internet] [Doctoral dissertation]. Normandie; Université de Sfax (Tunisie); 2017. [cited 2021 Jan 27].
Available from: http://www.theses.fr/2017NORMLH25.
Council of Science Editors:
Mezghani-Chaari S. Effet de la pollution urbaine et industrielle sur le système endocrinien : évaluation des conséquences sur la reproduction de "Ruditapes decusatus" issue du golfe de Gabès (Tunisie) : Effect of urban and industrial pollution on the endocrine system : evaluation of the consequences on reproduction of "Ruditapes decussatus". [Doctoral Dissertation]. Normandie; Université de Sfax (Tunisie); 2017. Available from: http://www.theses.fr/2017NORMLH25

University of Arkansas
17.
Kamaz, Mohanad Ali Abdulsahib.
Removal of Endocrine Disrupting Compounds Using Membrane Bioreactor.
Degree: MSChE, 2017, University of Arkansas
URL: https://scholarworks.uark.edu/etd/2384
► The presence of endocrine disrupting compounds (EDCs) and pharmaceutically active compounds (PhAC) such as pesticides, personal care products, antibiotics and pharmaceutical compounds, in sewage,…
(more)
▼ The presence of
endocrine disrupting compounds (EDCs) and pharmaceutically active
compounds (PhAC) such as pesticides, personal care products, antibiotics and pharmaceutical
compounds, in sewage, industrial, and domestic waters has extensively become the major concern for health and environmental organizations. These
compounds have the ability to interact with mammalian
endocrine system and
disrupting their functions. The traditional activated sludge processes are designed to degrade solids, organic carbon and nitrogen loading. Although several treatment steps in a wastewater treatment plant can contribute to partial removal of EDCs, effective removal has been a challenge due to their resistant chemical and biological degradation and extreme low concentrations. Membrane bioreactor (MBR) used in this study is novella better water reclamation technology that shows several advantages including stable operation conditions due to long solid retention time (SRT); concentrated mixed liquor suspended solids (MLSS); and low F/M ration in comparison with conventional wastewater treatment. This research will utilize these advanced membrane technologies to develop wastewater treatment processes for removal of EDCs in order to recover and reuse wastewater to augment drinking water supplies. A set of model EDCs including acetaminophen, amoxicillin, atrazine, estrone, and triclosan were selected to study the removal by membrane bioreactor. Those
compounds were chosen based on their concentrations present in Oklahoma and Arkansas wastewater and to represent each group of
compounds. Optimized HPLC method was used for detection of these model
compounds. A Lab-scale MBR operated with real wastewater was tested under different operating conditions, such as retention time and volatile suspended solids concentrations to remove the spiked EDCs. The module MBR can reach desired chemical oxygen demand COD (< 30 ppm), Total nitrogen <10 ppm, and Nitrate nitrogen < 5 ppm in
different retention times. MBR have shown removal of amoxicillin, acetaminophen, triclosan with the efficiency can reach 100% while (50-55) % removal of atrazine can be achieved. Estrone disappearance was also more than 90%.
Advisors/Committee Members: Xianghong Qian, Ranil Wickramasinghe, Wen Zhang.
Subjects/Keywords: Endocrine Disrupting Compounds; Membrane Bioreactor; Microfiltration; Wastewater Treatment; Biochemistry; Endocrinology; Membrane Science
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Kamaz, M. A. A. (2017). Removal of Endocrine Disrupting Compounds Using Membrane Bioreactor. (Masters Thesis). University of Arkansas. Retrieved from https://scholarworks.uark.edu/etd/2384
Chicago Manual of Style (16th Edition):
Kamaz, Mohanad Ali Abdulsahib. “Removal of Endocrine Disrupting Compounds Using Membrane Bioreactor.” 2017. Masters Thesis, University of Arkansas. Accessed January 27, 2021.
https://scholarworks.uark.edu/etd/2384.
MLA Handbook (7th Edition):
Kamaz, Mohanad Ali Abdulsahib. “Removal of Endocrine Disrupting Compounds Using Membrane Bioreactor.” 2017. Web. 27 Jan 2021.
Vancouver:
Kamaz MAA. Removal of Endocrine Disrupting Compounds Using Membrane Bioreactor. [Internet] [Masters thesis]. University of Arkansas; 2017. [cited 2021 Jan 27].
Available from: https://scholarworks.uark.edu/etd/2384.
Council of Science Editors:
Kamaz MAA. Removal of Endocrine Disrupting Compounds Using Membrane Bioreactor. [Masters Thesis]. University of Arkansas; 2017. Available from: https://scholarworks.uark.edu/etd/2384

University of Lethbridge
18.
University of Lethbridge. Faculty of Arts and Science.
Effects of thyroid hormones, thyroid hormone disruptors, and treated wastewater on bullfrog tadpole chemosensory function and behaviour
.
Degree: 2017, University of Lethbridge
URL: http://hdl.handle.net/10133/4793
► Endocrine disrupting compounds (EDCs) are persistent in wastewater effluent and discharged into receiving waters. Some EDCs can interact with the thyroid system in vertebrates. The…
(more)
▼ Endocrine disrupting compounds (EDCs) are persistent in wastewater effluent and discharged into receiving waters. Some EDCs can interact with the thyroid system in vertebrates. The present study investigated the effects of TH disruption on olfactory responses in Lithobates (Rana) catesbeiana tadpoles. A neurophysiological and a behavioural technique were developed to study olfactory acuity in tadpoles. To investigate the effects of thyroid hormone (TH) disruption, tadpoles were exposed to either 3,5’,3-triiodothyronine (T3), thyroxine (T4), 17β-estradiol (E2), known EDCs, or wastewater effluent. Olfactory-mediated avoidance responses to a chemosensory stimulus were measured. Exposure to T3 and treated wastewater resulted in impaired avoidance responses. Exposures to T4, E2 and known EDCs had no effect on behavioural responses. These results indicated that EDCs in wastewater effluent may contribute to olfactory impairment through TH disruption. Chemosensory-mediated behaviour may serve as an environmentally relevant endpoint to determine possible effects of TH disruption in wastewater effluent receiving waters.
Subjects/Keywords: chemosensory-mediated behaviour;
endocrine disrupting compounds;
olfactory acuity;
premetamorphic tadpoles;
thyroid hormone disruption;
wastewater effluent
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Science, U. o. L. F. o. A. a. (2017). Effects of thyroid hormones, thyroid hormone disruptors, and treated wastewater on bullfrog tadpole chemosensory function and behaviour
. (Thesis). University of Lethbridge. Retrieved from http://hdl.handle.net/10133/4793
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Science, University of Lethbridge. Faculty of Arts and. “Effects of thyroid hormones, thyroid hormone disruptors, and treated wastewater on bullfrog tadpole chemosensory function and behaviour
.” 2017. Thesis, University of Lethbridge. Accessed January 27, 2021.
http://hdl.handle.net/10133/4793.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Science, University of Lethbridge. Faculty of Arts and. “Effects of thyroid hormones, thyroid hormone disruptors, and treated wastewater on bullfrog tadpole chemosensory function and behaviour
.” 2017. Web. 27 Jan 2021.
Vancouver:
Science UoLFoAa. Effects of thyroid hormones, thyroid hormone disruptors, and treated wastewater on bullfrog tadpole chemosensory function and behaviour
. [Internet] [Thesis]. University of Lethbridge; 2017. [cited 2021 Jan 27].
Available from: http://hdl.handle.net/10133/4793.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Science UoLFoAa. Effects of thyroid hormones, thyroid hormone disruptors, and treated wastewater on bullfrog tadpole chemosensory function and behaviour
. [Thesis]. University of Lethbridge; 2017. Available from: http://hdl.handle.net/10133/4793
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
19.
Germana de Paiva Pessoa.
AvaliaÃÃo de Desreguladores EndÃcrinos e do Micropoluente Colesterol em EstaÃÃes de Tratamento de Esgoto SanitÃrio.
Degree: PhD, 2012, Universidade Federal do Ceará
URL: http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=9139
;
► Os desreguladores endÃcrinos (DEs), cuja presenÃa em esgotos sanitÃrios deve-se principalmente aos hormÃnios naturais 17 β-estradiol (E2) e estrona (E1) e ao sintÃtico 17α-etinilestradiol (EE2),…
(more)
▼ Os desreguladores endÃcrinos (DEs), cuja presenÃa em esgotos sanitÃrios deve-se principalmente aos hormÃnios naturais 17 β-estradiol (E2) e estrona (E1) e ao sintÃtico 17α-etinilestradiol (EE2), principal substÃncia ativa do contraceptivo oral, podem causar uma sÃrie de distÃrbios nos ÃrgÃos reprodutores dos seres humanos e animais, haja vista que tais compostos nÃo sÃo prontamente removidos por processos biolÃgicos de tratamento convencionais, sendo lanÃados de forma inadequada em corpos dâÃgua. No entanto, os compostos supramencionados se encontram em baixas concentraÃÃes (ng.L-1/μg.L -1) em matrizes ambientais aquosas, tornando sua detecÃÃo e quantificaÃÃo um desafio analÃtico. Deste modo, buscou-se desenvolver e otimizar uma metodologia analÃtica utilizando a tÃcnica de cromatografia gasosa acoplada a espectrometria de massas (CG/MS) com o objetivo de avaliar a eficiÃncia de remoÃÃo dos DEs e do micropoluente colesterol (CHOL) em EstaÃÃes de Tratamento de Esgotos (ETEs) da RegiÃo Metropolitana de Fortaleza, assim como detectÃ-los em Ãguas superficiais. Foram realizados ensaios de ecotoxicidade aguda e crÃnica com os efluentes e DEs, utilizando o microcrustÃceo Daphnia magna como bioindicador. Foram avaliadas cinco ETEs, sendo quatro tipos de tecnologias, a saber: duas ETEs com lagoa facultativa seguida de lagoa de maturaÃÃo (LF+LM1 e LF+LM2), lagoa facultativa (LF), lodos ativados seguido da etapa de cloraÃÃo (LA+Cl) e reator de manta de lodo e fluxo ascendente seguido da etapa de cloraÃÃo (UASB+Cl). As concentraÃÃes mÃdias para os micropoluentes nos efluentes foram: 557,4 ng.L-1 (E1); 144,4 ng.L-1 (E2); 266,4 ng.L-1 (E2-17A); 421,4 ng.L-1 (EE2) e 4691,9 ng.L-1 (CHOL). Os valores mÃximos obtidos nas Ãguas superficiais foram de: 212,75 ng.L-1 (E1); 256,25 ng.L-1 (E2) e 1175 ng.L-1 (CHOL). Os estrogÃnios E2-17A e EE2 nÃo foram detectados. Com relaÃÃo à remoÃÃo dos DEs, as menores eficiÃncias de remoÃÃo foram encontradas para os sistemas de baixa taxa (lagoas de estabilizaÃÃo) com 68,1% (LF+LM1); 79,9% (LF+LM2) e 54,0% (LF). Os sistemas de alta taxa obtiveram eficiÃncias de remoÃÃo satisfatÃrias: 93,4% (LA+Cl); 95,4% (UASB+Cl). Para o CHOL o melhor Ãndice de remoÃÃo foi obtido na ETE LF+LM2 com 94%, seguida das ETEs LA+Cl (88%) e UASB+Cl (82%). Com relaÃÃo à avaliaÃÃo ecotoxicolÃgica aguda, nÃo foi detectada toxicidade no efluente proveniente da ETE LF+LM2, entretanto, nos efluentes da LF+LM1 e LF, a CE50-48h mÃxima foi de 61% e 57%, respectivamente. O nÃvel de toxicidade nos efluentes das ETE LA+Cl e UASB+Cl foi maior que o obtido nos afluentes. Provavelmente, o aumento de toxicidade deve-se à presenÃa de cloro residual no efluente, uma vez que este era coletado apÃs a etapa de cloraÃÃo. Tratando-se de toxicidade crÃnica, foi detectado efeito significativo em termos de reproduÃÃo (p < 0,05) apenas no efluente proveniente da ETE LF+LM2 com CENO (concentraÃÃo de efeito nÃo observado) de 20% e CEO (concentraÃÃo de efeito observado) de 30%. Nos efluentes provenientes das ETE LA+Cl e UASB+Cl, o valor de…
Advisors/Committee Members: Ronaldo Ferreira do Nascimento, Andrà Bezerra dos Santos, AntÃnio Idivan Vieira Nunes, Silvano Porto Pereira, Luciano Matos Queiroz.
Subjects/Keywords: ENGENHARIA CIVIL; Saneamento ambiental; Endocrine disrupting compounds. Waste Wastewater Treatment Plant, Gas Chromatography, Ecotoxicology, Emerging micropollutants; Cromatografia gasosa; Ãguas residuais - PurificaÃÃo
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Pessoa, G. d. P. (2012). AvaliaÃÃo de Desreguladores EndÃcrinos e do Micropoluente Colesterol em EstaÃÃes de Tratamento de Esgoto SanitÃrio. (Doctoral Dissertation). Universidade Federal do Ceará. Retrieved from http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=9139 ;
Chicago Manual of Style (16th Edition):
Pessoa, Germana de Paiva. “AvaliaÃÃo de Desreguladores EndÃcrinos e do Micropoluente Colesterol em EstaÃÃes de Tratamento de Esgoto SanitÃrio.” 2012. Doctoral Dissertation, Universidade Federal do Ceará. Accessed January 27, 2021.
http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=9139 ;.
MLA Handbook (7th Edition):
Pessoa, Germana de Paiva. “AvaliaÃÃo de Desreguladores EndÃcrinos e do Micropoluente Colesterol em EstaÃÃes de Tratamento de Esgoto SanitÃrio.” 2012. Web. 27 Jan 2021.
Vancouver:
Pessoa GdP. AvaliaÃÃo de Desreguladores EndÃcrinos e do Micropoluente Colesterol em EstaÃÃes de Tratamento de Esgoto SanitÃrio. [Internet] [Doctoral dissertation]. Universidade Federal do Ceará 2012. [cited 2021 Jan 27].
Available from: http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=9139 ;.
Council of Science Editors:
Pessoa GdP. AvaliaÃÃo de Desreguladores EndÃcrinos e do Micropoluente Colesterol em EstaÃÃes de Tratamento de Esgoto SanitÃrio. [Doctoral Dissertation]. Universidade Federal do Ceará 2012. Available from: http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=9139 ;

Universiteit Utrecht
20.
Roelofs, M.J.E.
Steroidogenesis in vitro : towards relevant models for endocrine disruptor screening.
Degree: 2016, Universiteit Utrecht
URL: http://dspace.library.uu.nl:8080/handle/1874/331180
► Starting our search for in vitro alternative methods to screen for steroidogenesis toxicity, we focused on the effects of (suggested) endocrine disrupting compounds (EDCs) on…
(more)
▼ Starting our search for in vitro alternative methods to screen for steroidogenesis toxicity, we focused on the effects of (suggested)
endocrine disrupting compounds (EDCs) on cytochrome P450 17 (CYP17) enzyme activity. CYP17 is responsible for conversion of progestagens to dehydroepiandrosterone (DHEA), the main precursor for androgens and estrogens, important for (fetal) sexual functioning and development. We developed a new assay to screen for effects on CYP17 activity using porcine adrenal cortex microsomes (PACMs) and compared this with the well-known H295R steroidogenesis assay. Also, effects of selected
compounds on CYP19 (aromatase) activity in the H295R assay as well as human placental microsomes were assessed. 28 (suggested) EDCs were screened. The PACM assay showed to be an effective, rapid tool for screening of direct interaction of EDCs with CYP17. Furthermore, we discovered that CYP17 activity is regulated differently from CYP19. The addition of a specific and validated CYP17 assay to an EDC screening battery would be of added value on top of the existing steroidogenesis assays that mainly consider effects on the CYP19 enzyme. We further investigated a specific class of suggested EDCs: the conazole fungicide, some of which have been shown to affect male fertility parameters in vitro and in vivo. Ten conazole fungicides were selected and tested for potential in vitro (anti-)androgenic effects using the murine MA-10 cell line as well as an androgen receptor (AR) activity reporter assay. Exposure of MA-10 cells to six of these conazoles resulted in a decrease in basal testosterone (T) secretion. Nine of the tested conazole fungicides showed an inhibition of T-induced AR activation. Thus, several of the tested conazole fungicides showed distinct in vitro anti-androgenic effects in the performed assays. These effects are a result of two mechanisms, i.e. inhibition of T secretion and AR antagonism, suggesting that these
compounds are potential testicular toxicants in vivo. Subsequently, the effects of two bisphenol analogues, two perfluorinated
compounds, and two phthalates on ABC efflux transporters in the blood-testis barrier (BTB) were studied. Bisphenol A (BPA), tetrabromobisphenol A (TBBPA), perfluorooctanoic acid (PFOA), as well as perfluorooctane-sulfonic acid (PFOS) inhibited breast cancer resistance protein (BCRP) activity. BPA and PFOA showed to be substrates for BCRP. TBBPA, PFOA, and PFOS also showed inhibition of multidrug resistance proteins 1 and 4 (MRP1/4) and P-glycoprotein. In MA-10 cells, BPA and TBBPA concentration-dependently increased T secretion. For TBBPA, this could be blocked by inhibition of MRPs, generating the hypothesis that transporter-mediated efflux of T precursors is inhibited by TBBPA resulting in a higher availability of precursors for T production. This research indicates that, in EDC risk assessment, ABC efflux transporters present in the BTB are of toxicological and clinical relevance for testicular toxicity and should be taken into account. Next, effects of these several…
Advisors/Committee Members: van den Berg, Martin, Piersma, Aldert, van Duursen, Majorie.
Subjects/Keywords: steroidogenesis; endocrine disrupting compounds; in vitro models; screening; DHEA; testosterone; CYP17; CYP19 (aromatase); androgen receptor; glucocorticoid receptor; bisphenol analogues; conazole fungicides
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Roelofs, M. J. E. (2016). Steroidogenesis in vitro : towards relevant models for endocrine disruptor screening. (Doctoral Dissertation). Universiteit Utrecht. Retrieved from http://dspace.library.uu.nl:8080/handle/1874/331180
Chicago Manual of Style (16th Edition):
Roelofs, M J E. “Steroidogenesis in vitro : towards relevant models for endocrine disruptor screening.” 2016. Doctoral Dissertation, Universiteit Utrecht. Accessed January 27, 2021.
http://dspace.library.uu.nl:8080/handle/1874/331180.
MLA Handbook (7th Edition):
Roelofs, M J E. “Steroidogenesis in vitro : towards relevant models for endocrine disruptor screening.” 2016. Web. 27 Jan 2021.
Vancouver:
Roelofs MJE. Steroidogenesis in vitro : towards relevant models for endocrine disruptor screening. [Internet] [Doctoral dissertation]. Universiteit Utrecht; 2016. [cited 2021 Jan 27].
Available from: http://dspace.library.uu.nl:8080/handle/1874/331180.
Council of Science Editors:
Roelofs MJE. Steroidogenesis in vitro : towards relevant models for endocrine disruptor screening. [Doctoral Dissertation]. Universiteit Utrecht; 2016. Available from: http://dspace.library.uu.nl:8080/handle/1874/331180

Penn State University
21.
Henry, Erin.
THE DEVELOPMENT OF AN ADVANCED TREATMENT PROCESS TO REMOVE ENDOCRINE-DISRUPTING COMPOUNDS FROM WASTEWATER USING PHANEROCHAETE CHRYSOSPORIUM.
Degree: 2011, Penn State University
URL: https://submit-etda.libraries.psu.edu/catalog/11936
► Endocrine-disrupting compounds (EDCs) have entered our wastewater in many forms including pesticides and prescription medications. Because typical wastewater treatment processes are not designed to remove…
(more)
▼ Endocrine-
disrupting compounds (EDCs) have entered our wastewater in many forms including pesticides and prescription medications. Because typical wastewater treatment processes are not designed to remove EDCs, some
compounds remain in the effluent. Upon discharge, EDCs are released into the environment, where they can harm aquatic species or reenter potable water supplies.
One potential solution to this problem involves the use of the white-rot fungus (WRF), Phanerochaete chrysosporium. P. chrysosporium produces lignin-degrading extracellular enzymes, which have the capacity to biodegrade a variety of organic pollutants. Although there have been numerous experiments exploring the degradation capacity of WRF, there have not been adequate studies involving wastewater applications. This bench-scale study investigated conditions for fungal growth and extracellular enzyme activity in wastewater for eventual large-scale applications. Degradation of an EDC, atrazine, by P. chrysosporium was also evaluated.
Three batch experiments were carried out to evaluate the growth and extracellular enzyme activity of immobilized P. chrysosporium. The effects of sterile and non-sterile conditions, an organic carbon amendment, pH, wastewater effluent treatment, and three packing (immobilization) materials on P. chrysosporium were evaluated. Additionally, wastewater was spiked with atrazine, and degradation was monitored. In anticipation of scale-up, continuous-flow column reactors were designed and built; however, experimental data was not obtained from these columns.
The batch experiments indicated that 1) enzyme activity can be produced within a pH range of 3.4 – 5.1; 2) supplemental organic carbon positively affected growth, but did not affect enzyme activity; 3) fluctuations in pH negatively affected enzyme activity; 4) enzyme activity was produced in non-sterile wastewater; and 5) removal of atrazine by fungal treatments was not significantly different from controls; however, one fungal treatment may have started to degrade atrazine via enzymatic biocatalysis by the end of the experiment.
Advisors/Committee Members: Rachel Alice Brennan, Thesis Advisor/Co-Advisor, Rachel Alice Brennan, Thesis Advisor/Co-Advisor.
Subjects/Keywords: endocrine disrupting compounds; wastewater; white rot fungi; phanerochaete chrysosporium; atrazine; pH; glucose; sterile; non-sterile; batch study
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Henry, E. (2011). THE DEVELOPMENT OF AN ADVANCED TREATMENT PROCESS TO REMOVE ENDOCRINE-DISRUPTING COMPOUNDS FROM WASTEWATER USING PHANEROCHAETE CHRYSOSPORIUM. (Thesis). Penn State University. Retrieved from https://submit-etda.libraries.psu.edu/catalog/11936
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Henry, Erin. “THE DEVELOPMENT OF AN ADVANCED TREATMENT PROCESS TO REMOVE ENDOCRINE-DISRUPTING COMPOUNDS FROM WASTEWATER USING PHANEROCHAETE CHRYSOSPORIUM.” 2011. Thesis, Penn State University. Accessed January 27, 2021.
https://submit-etda.libraries.psu.edu/catalog/11936.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Henry, Erin. “THE DEVELOPMENT OF AN ADVANCED TREATMENT PROCESS TO REMOVE ENDOCRINE-DISRUPTING COMPOUNDS FROM WASTEWATER USING PHANEROCHAETE CHRYSOSPORIUM.” 2011. Web. 27 Jan 2021.
Vancouver:
Henry E. THE DEVELOPMENT OF AN ADVANCED TREATMENT PROCESS TO REMOVE ENDOCRINE-DISRUPTING COMPOUNDS FROM WASTEWATER USING PHANEROCHAETE CHRYSOSPORIUM. [Internet] [Thesis]. Penn State University; 2011. [cited 2021 Jan 27].
Available from: https://submit-etda.libraries.psu.edu/catalog/11936.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Henry E. THE DEVELOPMENT OF AN ADVANCED TREATMENT PROCESS TO REMOVE ENDOCRINE-DISRUPTING COMPOUNDS FROM WASTEWATER USING PHANEROCHAETE CHRYSOSPORIUM. [Thesis]. Penn State University; 2011. Available from: https://submit-etda.libraries.psu.edu/catalog/11936
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Brigham Young University
22.
Salehi, Sayed Mohammad.
Engineering Cell-free Protein Synthesis Technology for Codon Reassignment, Biotherapeutics Production using Just-add-Water System, and Biosensing Endocrine Disrupting Compounds.
Degree: PhD, 2017, Brigham Young University
URL: https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=7711&context=etd
► Cell-free protein synthesis is an emerging technology that has many applications. The open nature of this system makes it a compelling technology that can be…
(more)
▼ Cell-free protein synthesis is an emerging technology that has many applications. The open nature of this system makes it a compelling technology that can be manipulated to answer many needs that are unavailable in other systems. This dissertation reports on engineering this technology for: 1) sense codon emancipation for incorporation of multiple unnatural amino acids; 2) expressing a hard-to-express anticancer biotherapeutic and introducing a just-add-water system; 3) a biosensing ligand that interacts with nuclear hormone receptors. Emancipating sense codons toward a minimized genetic code is of significant interest to science and engineering. A promising approach to sense codon emancipation is the targeted in vitro removal of native tRNA. Here we introduce a new in-vitro or "cell-free" approach to emancipate sense codons via efficient and affordable degradation of endogenous tRNA using RNase-coated superparamagnetic beads. The presented method removes greater than 99% of tRNA in cell lysates, while preserving cell-free protein synthesis activity. The resulting tRNA-depleted lysate is compatible with in vitro-transcribed synthetic tRNA for the production of peptides and proteins. Biotherapeutics have many promising applications, such as anti-cancer treatments, immune suppression, and vaccines. However, due to their biological nature, some biotherapeutics can be challenging to rapidly express and screen for activity through traditional recombinant methods. In this work, we demonstrate the use of cell-free systems for the expression and direct screening of the difficult-to-express cytotoxic protein onconase. Using cell-free systems, onconase can be rapidly expressed in soluble, active form. Furthermore, the open nature of the reaction environment allows for direct and immediate downstream characterization without the need of purification. Also, we report the ability of a "just-add-water" lyophilized cell-fee system to produce onconase. Here we introduce a Rapid Adaptable Portable In-vitro Detection biosensor platform (RAPID) for detecting ligands that interact with nuclear hormone receptors (NHRs). The biosensor is based on an engineered, allosterically-activated fusion protein, which contains the ligand binding domain from a target NHR. The presented RAPID biosensor platform is significantly faster and less labor intensive than commonly available technologies, making it a promising tool for detecting environmental EDC contamination and screening potential NHR-targeted pharmaceuticals.
Subjects/Keywords: Sayed Mohammad Amin Salehi; cell-free protein synthesis; codon emancipation; cancer biotherapeutics; endocrine disrupting compounds; nuclear hormone receptors; biosensor; Chemical Engineering
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Salehi, S. M. (2017). Engineering Cell-free Protein Synthesis Technology for Codon Reassignment, Biotherapeutics Production using Just-add-Water System, and Biosensing Endocrine Disrupting Compounds. (Doctoral Dissertation). Brigham Young University. Retrieved from https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=7711&context=etd
Chicago Manual of Style (16th Edition):
Salehi, Sayed Mohammad. “Engineering Cell-free Protein Synthesis Technology for Codon Reassignment, Biotherapeutics Production using Just-add-Water System, and Biosensing Endocrine Disrupting Compounds.” 2017. Doctoral Dissertation, Brigham Young University. Accessed January 27, 2021.
https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=7711&context=etd.
MLA Handbook (7th Edition):
Salehi, Sayed Mohammad. “Engineering Cell-free Protein Synthesis Technology for Codon Reassignment, Biotherapeutics Production using Just-add-Water System, and Biosensing Endocrine Disrupting Compounds.” 2017. Web. 27 Jan 2021.
Vancouver:
Salehi SM. Engineering Cell-free Protein Synthesis Technology for Codon Reassignment, Biotherapeutics Production using Just-add-Water System, and Biosensing Endocrine Disrupting Compounds. [Internet] [Doctoral dissertation]. Brigham Young University; 2017. [cited 2021 Jan 27].
Available from: https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=7711&context=etd.
Council of Science Editors:
Salehi SM. Engineering Cell-free Protein Synthesis Technology for Codon Reassignment, Biotherapeutics Production using Just-add-Water System, and Biosensing Endocrine Disrupting Compounds. [Doctoral Dissertation]. Brigham Young University; 2017. Available from: https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=7711&context=etd

University of the Western Cape
23.
Sidwaba, Unathi.
Development of nanobiosensors for phenolic endocrine disrupting compounds and anti- tuberculosis drugs
.
Degree: 2013, University of the Western Cape
URL: http://hdl.handle.net/11394/3888
► Tuberculosis still remains one of the world’s killer diseases. Pyrazinamide (PZA) is one of the most commonly prescribed anti-tuberculosis (anti-TB) drugs due to its ability…
(more)
▼ Tuberculosis still remains one of the world’s killer diseases. Pyrazinamide (PZA) is one of
the most commonly prescribed anti-tuberculosis (anti-TB) drugs due to its ability to
significantly shorten the TB treatment period. However, excess PZA in the body caused
hepatotoxicity and liver damage. This, together with the resistance of the bacteria to
treatment drugs, poor medication and inappropriate dosing, contribute significantly to the high incidents of TB deaths and diseases (such as liver damage). This, therefore, calls for new methods for ensuring reliable dosing of the drug, which will differ from person to person due to inter-individual differences in drug metabolism. A novel biosensor system for monitoring the metabolism of PZA was prepared with a nanocomposite of multi-walled carbon nanotubes (MWCNTs), polyaniline (PANI) and cytochrome P450 2E1 (CYP2E1) electrochemically deposited on a glassy carbon electrode (GCE). The nanocomposite biosensor system exhibited enhanced electro-activity that is attributed to the catalytic effect of the incorporated MWCNTs. The biosensor had a sensitivity of 7.80 μA/ μg mL-1 PZA and a dynamic linear range (DLR) of 4.92 – 160 ng/mL PZA. Bisphenol A (BPA) is a hormone-
disrupting chemical used in production of epoxy resins and polycarbonates, which produce various products used on a daily basis. However, BPA can leach out of plastic during normal use and cause health effects such as cancer or disrupt the
endocrine system. Moreover, BPA has also been proven to degrade from the containers in landfills and accumulate in groundwater and streams, thereby, polluting the environment while destroying aquatic organisms. Therefore, this also calls for new selective and sensitive methods for the monitoring of BPA. A novel biosensor system for monitoring the oxidation of BPA was prepared from a nanocomposite of polyaniline, polymethyl methacrylate and titanium dioxide nanoparticles, also electrochemically deposited on the GCE. Biosensor fabrication was conducted by immobilization of the enzyme manganese peroxidase (MnP)
iii onto the nanocomposite film. The nanobiosensor also revealed enhanced electro activity, attributed to the incorporation of TiO2 nanoparticles. The biosensor system had a sensitivity of 0.3 μA/nM and a detection limit of 0.12 nM. This detection limit falls within the range of the allowed daily intake of BPA as recommended by the Food and Drug Administration (FDA, USA) and other regulatory bodies.
Advisors/Committee Members: Iwuoha, Emmanuel (advisor).
Subjects/Keywords: Tuberculosis;
Bisphenol A;
Mycobacterium tuberculosis;
Polyaniline;
Titanium dioxide nanoparticles;
Pyrazinamide;
Carbon nanotubes;
Cytochrome P450-2E1;
Manganese peroxidase;
Endocrine disrupting compounds
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Sidwaba, U. (2013). Development of nanobiosensors for phenolic endocrine disrupting compounds and anti- tuberculosis drugs
. (Thesis). University of the Western Cape. Retrieved from http://hdl.handle.net/11394/3888
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Sidwaba, Unathi. “Development of nanobiosensors for phenolic endocrine disrupting compounds and anti- tuberculosis drugs
.” 2013. Thesis, University of the Western Cape. Accessed January 27, 2021.
http://hdl.handle.net/11394/3888.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Sidwaba, Unathi. “Development of nanobiosensors for phenolic endocrine disrupting compounds and anti- tuberculosis drugs
.” 2013. Web. 27 Jan 2021.
Vancouver:
Sidwaba U. Development of nanobiosensors for phenolic endocrine disrupting compounds and anti- tuberculosis drugs
. [Internet] [Thesis]. University of the Western Cape; 2013. [cited 2021 Jan 27].
Available from: http://hdl.handle.net/11394/3888.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Sidwaba U. Development of nanobiosensors for phenolic endocrine disrupting compounds and anti- tuberculosis drugs
. [Thesis]. University of the Western Cape; 2013. Available from: http://hdl.handle.net/11394/3888
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of the Western Cape
24.
Qakala, Sinazo.
Towards rapid electrochemical test system of polyanilino-laccase-on-gold enzyme nanobiosensor for water estrogens
.
Degree: 2013, University of the Western Cape
URL: http://hdl.handle.net/11394/3937
► Current water treatment technologies do not remove many endocrine disruptor compounds (EDCs) such as 17α-ethynylestradiol (EE2) in its entirety, and the amount of these pollutants…
(more)
▼ Current water treatment technologies do not remove many
endocrine disruptor
compounds (EDCs) such as 17α-ethynylestradiol (EE2) in its entirety, and the amount of these pollutants that continues to enter the aquatic environment through wastewater effluents is still capable of causing harmful health effects. Therefore the development of simpler and more sensitive biosensor system for detection of EE2 must be developed which have high responsiveness, low cost and easy handling. Therefore the aim of this study was to work towards the development of rapid test system of polyaniline-laccase on gold enzyme nanobiosensor (PANI-PSSA/Lac/Glu) for water estrogens. Preliminary studies were first done on the materials used in this study: estrogens, laccase, gold nanoparticles (AuNPs), and electropolymerized PANI-PSSA. Laccase was shown to be active towards EE2 and the enzyme could be stored for over three months. EE2 solution also could be used for over three
months. Buffer used in this study was found to be suitable. Phosphoric acid (H3PO4) was a suitable electrolyte than hydrochloric acid (HCl) to be used for the electropolymerization of aniline and was used because it has same ions as the McIlvaine buffer (McIlB) which the post-deposition CVs indicated the formation of electrochemically very stable film. AuNPs were successfully synthesized and its size was identified to be less than 22 nm. McIlB used for testing electrochemical properties of AuNP. CVs of GC/PANI-PSSA and GC/PANIPSSA/ Au showed no difference before and after exposure to aq. EE2 solution, an indication of being re-usable and could also serve as stable immobilising platform in laccase biosensor.
When interrogating with electrochemical impedance spectroscopy (EIS), the charge transfer resistance (Rct) of both GC/PANI-PSSA and GC/PANI-PSSA/Lac/Glu showed an average increase by about 2.4% and 21% before and after exposure of EE2, respectively. This shows that the GC/PANI-PSSA/Lac/Glu was a functional EE2 biosensor and showing a positive step towards achieving a re-usable biosensor for EE2 as a model water estrogen. Future work Page | vi will focus on exploring different ways of improving the biosensor’s surface regeneration and its sensitivity to EE2.
Advisors/Committee Members: Iwuoha, Emmanuel (advisor), Waryo, Tesfaye T (advisor).
Subjects/Keywords: 17α-ethnylestradiol;
17β-estradiol;
Estriol;
Estrone;
Laccase (Trametes versicolor);
Gold nanoparticles;
Cyclic voltammetry;
Polyaniline;
Enzyme biosensor;
Endocrine disrupting compounds
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Qakala, S. (2013). Towards rapid electrochemical test system of polyanilino-laccase-on-gold enzyme nanobiosensor for water estrogens
. (Thesis). University of the Western Cape. Retrieved from http://hdl.handle.net/11394/3937
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Qakala, Sinazo. “Towards rapid electrochemical test system of polyanilino-laccase-on-gold enzyme nanobiosensor for water estrogens
.” 2013. Thesis, University of the Western Cape. Accessed January 27, 2021.
http://hdl.handle.net/11394/3937.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Qakala, Sinazo. “Towards rapid electrochemical test system of polyanilino-laccase-on-gold enzyme nanobiosensor for water estrogens
.” 2013. Web. 27 Jan 2021.
Vancouver:
Qakala S. Towards rapid electrochemical test system of polyanilino-laccase-on-gold enzyme nanobiosensor for water estrogens
. [Internet] [Thesis]. University of the Western Cape; 2013. [cited 2021 Jan 27].
Available from: http://hdl.handle.net/11394/3937.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Qakala S. Towards rapid electrochemical test system of polyanilino-laccase-on-gold enzyme nanobiosensor for water estrogens
. [Thesis]. University of the Western Cape; 2013. Available from: http://hdl.handle.net/11394/3937
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
25.
HUANG ZHENZHEN.
DEVELOPMENT OF MINIATURIZED EXTRACTION METHODS WITH ADVANCES OF NOVEL SORBENT MATERIALS FOR ENVIRONMENTAL ANALYSIS.
Degree: 2015, National University of Singapore
URL: http://scholarbank.nus.edu.sg/handle/10635/121772
Subjects/Keywords: Sample preparation; microextraction; sorbent; endocrine disrupting compounds; environmental analysis
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
ZHENZHEN, H. (2015). DEVELOPMENT OF MINIATURIZED EXTRACTION METHODS WITH ADVANCES OF NOVEL SORBENT MATERIALS FOR ENVIRONMENTAL ANALYSIS. (Thesis). National University of Singapore. Retrieved from http://scholarbank.nus.edu.sg/handle/10635/121772
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
ZHENZHEN, HUANG. “DEVELOPMENT OF MINIATURIZED EXTRACTION METHODS WITH ADVANCES OF NOVEL SORBENT MATERIALS FOR ENVIRONMENTAL ANALYSIS.” 2015. Thesis, National University of Singapore. Accessed January 27, 2021.
http://scholarbank.nus.edu.sg/handle/10635/121772.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
ZHENZHEN, HUANG. “DEVELOPMENT OF MINIATURIZED EXTRACTION METHODS WITH ADVANCES OF NOVEL SORBENT MATERIALS FOR ENVIRONMENTAL ANALYSIS.” 2015. Web. 27 Jan 2021.
Vancouver:
ZHENZHEN H. DEVELOPMENT OF MINIATURIZED EXTRACTION METHODS WITH ADVANCES OF NOVEL SORBENT MATERIALS FOR ENVIRONMENTAL ANALYSIS. [Internet] [Thesis]. National University of Singapore; 2015. [cited 2021 Jan 27].
Available from: http://scholarbank.nus.edu.sg/handle/10635/121772.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
ZHENZHEN H. DEVELOPMENT OF MINIATURIZED EXTRACTION METHODS WITH ADVANCES OF NOVEL SORBENT MATERIALS FOR ENVIRONMENTAL ANALYSIS. [Thesis]. National University of Singapore; 2015. Available from: http://scholarbank.nus.edu.sg/handle/10635/121772
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Minnesota
26.
Fairbairn, David Joel.
Sources, Transport, and Sediment-Water Distributions of Contaminants of Emerging Concern in a Mixed-Use Watershed.
Degree: PhD, Water Resources Science, 2015, University of Minnesota
URL: http://hdl.handle.net/11299/177673
► Understanding the sources and transport of contaminants of emerging concern (CECs) is crucial for risk assessment and mitigation. The goal of this research was to…
(more)
▼ Understanding the sources and transport of contaminants of emerging concern (CECs) is crucial for risk assessment and mitigation. The goal of this research was to augment this knowledge by characterizing the spatiotemporal variability of a diverse set of CECs in a mixed land-use watershed. The study area (South Zumbro Watershed, Minnesota) presented a gradient of land uses that facilitated the investigation of agricultural and urban/residential sources and transport of CECs. Concentrations and loadings of CECs in water samples were analyzed in light of spatial, temporal, hydrologic, and physicochemical variables. Contaminant mass balances were analyzed to characterize the proportional sources and instream transport of CECs. Sediment-water distributions of CECs were assessed in terms of their magnitude, variability, and predictability. Three distinct CEC groups emerged with respect to sources, transport, and seasonal/temporal patterns. The first group (i.e., atrazine, acetochlor, metolachlor, and daidzein) was characterized by agricultural/upstream-dominated sources and transport. These CECs were input primarily via upstream routes with loadings and concentrations that were greatest during high flows. For the second group (i.e., acetaminophen, trimethoprim, DEET, caffeine, cotinine, and mecoprop), a mix of wastewater and runoff transport was demonstrated by frequent detections in effluent and upstream samples, with peak loadings/concentrations associated with high flows and areas of greater population density/development. For the third group (i.e., sulfamethoxazole, carbamazepine, erythromycin, tylosin, carbaryl, and 4-nonylphenol), the detections, concentrations, and loadings were explained by effluent-dominated sources and transport. These CECs showed expected trends of stable loading across events, with the greatest concentrations and detection frequencies associated with low flows and the wastewater treatment plant. Average measured sediment-water distributions exceeded equilibrium hydrophobic-based predictions for five of seven detected CECs by at least an order of magnitude. The consistency and predictability of the measured distributions improved with increasing CEC hydrophobicity and persistence. Thus, spatiotemporal analysis can be used to characterize and track CEC sources and transport, even for ubiquitous CECs. These results augment existing knowledge of CEC sources, fate, and transport by describing dominant sources, transport, and temporal patterns for different types of CECs. This will enhance monitoring, exposure/risk assessments, and management of CECs in surface water ecosystems.
Subjects/Keywords: Water resources management; Environmental science; Organic chemistry; Contaminants of Emerging Concern; Endocrine Disrupting Compounds; Land Use; Seasonality; Sediment; Surface Water
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APA ·
Chicago ·
MLA ·
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APA (6th Edition):
Fairbairn, D. J. (2015). Sources, Transport, and Sediment-Water Distributions of Contaminants of Emerging Concern in a Mixed-Use Watershed. (Doctoral Dissertation). University of Minnesota. Retrieved from http://hdl.handle.net/11299/177673
Chicago Manual of Style (16th Edition):
Fairbairn, David Joel. “Sources, Transport, and Sediment-Water Distributions of Contaminants of Emerging Concern in a Mixed-Use Watershed.” 2015. Doctoral Dissertation, University of Minnesota. Accessed January 27, 2021.
http://hdl.handle.net/11299/177673.
MLA Handbook (7th Edition):
Fairbairn, David Joel. “Sources, Transport, and Sediment-Water Distributions of Contaminants of Emerging Concern in a Mixed-Use Watershed.” 2015. Web. 27 Jan 2021.
Vancouver:
Fairbairn DJ. Sources, Transport, and Sediment-Water Distributions of Contaminants of Emerging Concern in a Mixed-Use Watershed. [Internet] [Doctoral dissertation]. University of Minnesota; 2015. [cited 2021 Jan 27].
Available from: http://hdl.handle.net/11299/177673.
Council of Science Editors:
Fairbairn DJ. Sources, Transport, and Sediment-Water Distributions of Contaminants of Emerging Concern in a Mixed-Use Watershed. [Doctoral Dissertation]. University of Minnesota; 2015. Available from: http://hdl.handle.net/11299/177673

University of South Florida
27.
Siegel, Kristy.
Fate of polybrominated diphenyl ethers during wastewater treatment process producing reclaimed water.
Degree: 2013, University of South Florida
URL: https://scholarcommons.usf.edu/etd/4943
► Polybrominated diphenyl ethers (PBDEs), flame retardants, have been applied to consumer goods, such as furniture, electrical devices, textiles, and appliances for decades. Due to their…
(more)
▼ Polybrominated diphenyl ethers (PBDEs), flame retardants, have been applied to consumer goods, such as furniture, electrical devices, textiles, and appliances for decades. Due to their physico-chemical properties, PBDEs are semi-volatile and easily leach off the consumer good during aging, stress, or normal wear and tear of the good. Once airborne, they pose an environmental health threat because they can adsorb onto dust particles, soil, or other particulates that can be inhaled, ingested, or come into contact with the dermal layer. Additionally, PBDEs have a molecular structure similar to other persistent organic pollutants, such as polychlorinated biphenyls and polychlorinated dibenzo-p-dioxins and furans. They are a health threat due to their endocrine-disrupting nature by affecting thyroid functioning, fertility, and child development. The purpose of the study is to measure selected PBDEs in a wastewater treatment plant (WWTP) that produces reclaimed water, such that a mass balance can be completed, and to compare this mass balance with theoretically expected concentrations. The mass balance includes the collection of samples from wastewater, sewage sludge, and air at points within the WWTP. The PBDEs examined are BDE-28, 47, 99, 100, 153, 154, and 183. The second part of the study will compare effluent concentrations to reclaimed water concentrations in order to examine the potential exposure (if any) of using reclaimed water. Influent concentration of mean (sum7)PBDE was found to be 49,117 pg/L and effluent concentration was 4,603 pg/L, illustrating a 91% removal rate of PBDEs during the wastewater treatment plant. Sludge samples contained the highest total concentrations of PBDEs with mean (sum7)PBDE ranging from 14.0 to 41.3 ug/kg dry weight. Air samples were highest at the post-aeration (248 pg/m3 mean (sum7)PBDE) step due to the use of highly oxygenated air assisting in the release and volatilization of the PBDEs. Sludge was found to carry the largest mass loading at 14.2 lb/day (sum7)PBDE. Of the total mass loading of PBDEs from the WWTP, sludge is responsible for 86.7%, followed by reclaimed water and effluent (11.7% and 1.6%, respectively). The mass loading from air was negligible with less than 0.01% contribution to the total mass loading. Whereas reclaimed water overall had higher PBDE congener mean concentrations than the effluent, the independent samples t-test found no statistically significant differences between the two groups. The results of this study can be used to improve the wastewater treatment process to reduce the impact of PBDEs being released into the environment by WWTPs, and to educate the public on utilizing reclaimed water in a safe and healthy manner.
Subjects/Keywords: brominated flame retardants; mass loading; persistent organic pollutants; point source; endocrine disrupting compounds; Environmental Health and Protection; Public Health
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Siegel, K. (2013). Fate of polybrominated diphenyl ethers during wastewater treatment process producing reclaimed water. (Thesis). University of South Florida. Retrieved from https://scholarcommons.usf.edu/etd/4943
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Siegel, Kristy. “Fate of polybrominated diphenyl ethers during wastewater treatment process producing reclaimed water.” 2013. Thesis, University of South Florida. Accessed January 27, 2021.
https://scholarcommons.usf.edu/etd/4943.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Siegel, Kristy. “Fate of polybrominated diphenyl ethers during wastewater treatment process producing reclaimed water.” 2013. Web. 27 Jan 2021.
Vancouver:
Siegel K. Fate of polybrominated diphenyl ethers during wastewater treatment process producing reclaimed water. [Internet] [Thesis]. University of South Florida; 2013. [cited 2021 Jan 27].
Available from: https://scholarcommons.usf.edu/etd/4943.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Siegel K. Fate of polybrominated diphenyl ethers during wastewater treatment process producing reclaimed water. [Thesis]. University of South Florida; 2013. Available from: https://scholarcommons.usf.edu/etd/4943
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
28.
Souza, Francisco Glaucio Cavalcante de.
Remoção de desreguladores endócrinos por fotocatálise heterogênea e ozonização.
Degree: PhD, Hidráulica e Saneamento, 2009, University of São Paulo
URL: http://www.teses.usp.br/teses/disponiveis/18/18138/tde-11052011-093441/
;
► Desreguladores endócrinos são compostos que podem alterar o sistema endócrino dos indivíduos, bem como sua fertilidade e por em risco a saúde dos mesmos. Muitas…
(more)
▼ Desreguladores endócrinos são compostos que podem alterar o sistema endócrino dos indivíduos, bem como sua fertilidade e por em risco a saúde dos mesmos. Muitas questões relacionadas a esses compostos ainda não foram elucidadas, apesar de serem muito estudados recentemente. Diversas pesquisas têm sido feitas investigando-se o emprego de processos oxidativos avançados na degradação dos desreguladores endócrinos em águas naturais e residuárias. O presente trabalho teve como objetivo estudar a remoção do hormônio 17\'beta\'-estradiol em soluções aquosas por oxidação química. A pesquisa foi dividida em duas etapas, sendo que a primeira etapa consistiu na investigação do uso de brometo de prata/dióxido de titânio (\'AG\'BR\'/\'TI\'O IND.2\') como catalisador no processo de fotocatálise com luz visível. Para isso, foram avaliadas a influência da concentração de \'AG\'BR\'/\'TI\'O IND.2(́0,020; 0,025; 0,050; 0,070 e 0,100 g/L) e a intensidade de luz visível incidente (6,6 x \'10 POT.5é 1,3 x \'10 POT.6Íx) na eficiência de degradação do 17\'beta\'-estradiol. Na segunda etapa avaliou-se o emprego de ozônio na degradação de 17\'beta\'-estradiol em soluções aquosas, variando-se as dosagens de ozônio (1,7; 3,3, 5,0 e 7,5 mg \'0 IND.3\'/L) aplicadas e o pH (3; 5; 7; 9 e 11) das amostras. Na primeira etapa, os resultados demonstram que E2 foi bastante sensível aos processos oxidativos empregados. A fotocatálise foi eficiente para oxidar 17\'beta\'-estradiol, demandando tempo de exposição pequeno, em torno de 4 minutos para obtenção de remoção da ordem de 98%, quando aplicada concentração de \'AG\'BR\'/\'TI\'O IND.2d́e 0,100 g/L e a intensidade de luz visível incidente de 1,3 x \'10 POT.6Íx. Na segunda etapa, observou-se que o aumento do pH promoveu maior rapidez na degradação do E2 e o aumento da massa de ozônio aplicada promoveu maior eficiência de degradação do 17\'beta\'-estradiol.
Endocrine disrupting chemicals are compounds that can alter the endocrine system of individuals and their fertility and threaten their health. Many issues related to these compounds have not been elucidated, although much studied recently. Many researchers have investigated the use of advanced oxidative processes in the degradation of endocrine disrupting compounds in water and wastewater. This work is a study of the removal of 17\'beta\'-estradiol in aqueous solutions by chemical oxidation. This work was divided into two stages. In the first one, the use of bromide of silver/titanium dioxide (\'AG\'BR\'/\'TI\'O IND.2\') was investigated as catalyst in the photocatalysis activity under visible light irradiation. It was evaluated the influence of the concentration of \'AG\'BR\'/\'TI\'O IND.2(́0.020; 0.025; 0.050; 0.070 and 0.100 g/L) and the incident light intensity (6.6 x \'10 POT.5ánd 1.3 x \'10 POT.6Íx) in the efficiency of degradation of 17\'beta\'-estradiol. In the second step, it was evaluated the use of ozone in the degradation of 17\'beta\'-estradiol in aqueous solutions, ranging up the masses of applied ozone (1.7;…
Advisors/Committee Members: Daniel, Luiz Antonio.
Subjects/Keywords: 17'beta'-estradiol; 17'beta'-estradiol; Advanced oxidative processes; Desreguladores endócrinos; Endocrine disrupting compounds; Fotocatálise heterogênea; Ozonation; Ozonização; Photocatalys; Processos oxidativos avançados
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Souza, F. G. C. d. (2009). Remoção de desreguladores endócrinos por fotocatálise heterogênea e ozonização. (Doctoral Dissertation). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/18/18138/tde-11052011-093441/ ;
Chicago Manual of Style (16th Edition):
Souza, Francisco Glaucio Cavalcante de. “Remoção de desreguladores endócrinos por fotocatálise heterogênea e ozonização.” 2009. Doctoral Dissertation, University of São Paulo. Accessed January 27, 2021.
http://www.teses.usp.br/teses/disponiveis/18/18138/tde-11052011-093441/ ;.
MLA Handbook (7th Edition):
Souza, Francisco Glaucio Cavalcante de. “Remoção de desreguladores endócrinos por fotocatálise heterogênea e ozonização.” 2009. Web. 27 Jan 2021.
Vancouver:
Souza FGCd. Remoção de desreguladores endócrinos por fotocatálise heterogênea e ozonização. [Internet] [Doctoral dissertation]. University of São Paulo; 2009. [cited 2021 Jan 27].
Available from: http://www.teses.usp.br/teses/disponiveis/18/18138/tde-11052011-093441/ ;.
Council of Science Editors:
Souza FGCd. Remoção de desreguladores endócrinos por fotocatálise heterogênea e ozonização. [Doctoral Dissertation]. University of São Paulo; 2009. Available from: http://www.teses.usp.br/teses/disponiveis/18/18138/tde-11052011-093441/ ;

Universidade do Rio Grande do Sul
29.
Castro, Carmen Maria Barros de.
Ocorrência de desreguladores endócrinos em cultura de milho irrigada com efluentes urbanos tratados.
Degree: 2010, Universidade do Rio Grande do Sul
URL: http://hdl.handle.net/10183/32458
► Devido à escassez de recursos hídricos, efluentes de plantas de tratamento de águas residuárias têm sido reutilizadas ou recicladas em todo o mundo. Em algumas…
(more)
▼ Devido à escassez de recursos hídricos, efluentes de plantas de tratamento de águas residuárias têm sido reutilizadas ou recicladas em todo o mundo. Em algumas regiões áridas e em particular em regiões semi-áridas, o reuso de água tem sido reconhecido como um valioso recurso. Entretanto, dependendo da natureza do uso, surgem preocupações sobre potenciais riscos associados à presença de patógenos e contaminantes e a saúde humana. Uma grande variedade de contaminantes orgânicos pode estar presente nos esgotos domésticos e ser recirculado pelo ambiente. Alguns desses compostos apresentam o potencial de desregular as funções normais do sistema endócrino dos organismos e assim, causar efeitos adversos sobre a saúde humana. Entre esses compostos, incluem-se os hormônios estrógenos naturais e sintéticos. Nesse trabalho, desenvolvido na Estação Experimental de Tratamento de Águas Residuárias Urbanas do IPH/UFRGS, localizada nas dependências da ETE São João – Navegantes / DMAE / Porto Alegre / RS, foi investigada a ocorrência de hormônios naturais e sintéticos em grãos de milho cultivados por processo de irrigação por sulcos com efluentes domésticos tratados. O método analítico utilizado para quantificação dos hormônios de interesse foi a cromatografia líquida de alto desempenho (HPLC). Os resultados obtidos confirmam a presença de hormônios naturais e sintéticos no esgoto bruto e nos efluentes tratados, mas em concentrações extremamente baixas e não indicam processo de transferência ou acúmulo desses contaminantes para os grãos de milho.
Due to the scarcity of fresh water resources, effluents from wastewater treatment plants have increasingly been reclaimed and reused around the world. In some arid and semiarid regions, in particular, reclaimed water has been recognized as a valuable resource for non-potable use such as irrigating crops. However, depending on the nature of application, there is concern about potential risks associated with pathogens and organic contaminants to the environment and human health. A wide range of organic contaminants may be present in wastewater and the environment receiving it. These include natural and synthetic estrogens have the potential to disrupt the normal function (s) of endocrine systems in organisms and thus causing health effects on wildlife and humans. In the present work, developed at “Estação Experimental de Tratamento de Águas Residuárias Urbanas do IPH/UFRGS”, located on the ETE São João – Navegantes /DMAE / Porto Alegre /RS, was investigated the occurrence of natural and synthetic hormones in corn’s grain (Zea mays) cultivated by furrow irrigation of treated domestic effluents. The analytic method used for the hormones quantification was the High Performance Liquid Chromatography (HPLC). The results confirm the presence of natural and synthetic hormones on the untreated and treated effluents, although with a very low concentration and not indicated accumulation of this one to the corn’s grain.
Advisors/Committee Members: Monteggia, Luiz Olinto.
Subjects/Keywords: Hormones; Hormônios; Endocrine disrupting compounds; Esgoto doméstico; Sewage; Zea mays; Reúso da água; Reclaimed water; Irrigacao : Sulcos; Furrow irrigation; Zea mays; Efluentes urbanos
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Castro, C. M. B. d. (2010). Ocorrência de desreguladores endócrinos em cultura de milho irrigada com efluentes urbanos tratados. (Thesis). Universidade do Rio Grande do Sul. Retrieved from http://hdl.handle.net/10183/32458
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Castro, Carmen Maria Barros de. “Ocorrência de desreguladores endócrinos em cultura de milho irrigada com efluentes urbanos tratados.” 2010. Thesis, Universidade do Rio Grande do Sul. Accessed January 27, 2021.
http://hdl.handle.net/10183/32458.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Castro, Carmen Maria Barros de. “Ocorrência de desreguladores endócrinos em cultura de milho irrigada com efluentes urbanos tratados.” 2010. Web. 27 Jan 2021.
Vancouver:
Castro CMBd. Ocorrência de desreguladores endócrinos em cultura de milho irrigada com efluentes urbanos tratados. [Internet] [Thesis]. Universidade do Rio Grande do Sul; 2010. [cited 2021 Jan 27].
Available from: http://hdl.handle.net/10183/32458.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Castro CMBd. Ocorrência de desreguladores endócrinos em cultura de milho irrigada com efluentes urbanos tratados. [Thesis]. Universidade do Rio Grande do Sul; 2010. Available from: http://hdl.handle.net/10183/32458
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
30.
Neyliane Costa de Souza.
DeterminaÃÃo de Micropoluentes Emergentes em Esgoto SanitÃrio, Hospitalar e Ãguas Superficiais.
Degree: PhD, 2011, Universidade Federal do Ceará
URL: http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=7099
;
► No Brasil, estudos de avaliaÃÃo de micropoluentes emergentes em matrizes ambientais como esgotos sanitÃrios e hospitalares, e corpos de Ãgua, ainda sÃo bastante incipientes, assim…
(more)
▼ No Brasil, estudos de avaliaÃÃo de micropoluentes emergentes em matrizes ambientais como esgotos sanitÃrios e hospitalares, e corpos de Ãgua, ainda sÃo bastante incipientes, assim como a remoÃÃo desses compostos em EstaÃÃes de Tratamento de Esgotos (ETEs) de baixo custo como lagoas de estabilizaÃÃo, assim como em sistemas de lodos ativados e sistemas anaerÃbio-aerÃbio compactos. O presente trabalho teve como objetivo geral investigar a presenÃa de micropoluentes em matrizes ambientais como esgotos sanitÃrios e hospitalares, e Ãgua superficial, avaliar a remoÃÃo destes compostos em ETEs de baixo custo e aplicar o processo de oxidaÃÃo avanÃada (POA) UV/H2O2 como opÃÃo de pÃs-tratamento. Os principais micropoluentes emergentes estudados foram: 2,4,6-triclorofenol, pentaclorofenol, cafeÃna (CAF), dipirona (DIP), diclofenaco de sÃdio (DCF), bis (2-etil-hexil) ftalato (DEHP), estrona (E1), 17β-estradiol (E2), β-estradiol 17-acetato (EA2), 17α-etinilestradiol (EE2) e colesterol (COL). As amostras foram coletadas em ETEs localizadas em Fortaleza e em sua regiÃo metropolitana. Os corpos receptores investigados foram o Rio Maranguapinho e o Riacho Paupina. Para a prÃ-concentraÃÃo dos micropoluentes utilizou-se extraÃÃo em fase sÃlida (SPE) com cartuchos C-18 e extraÃÃo lÃquido-lÃquido (ELL). A SPE foi a tÃcnica mais eficiente na concentraÃÃo da maioria dos micropoluentes emergentes, e a ELL se mostrou a melhor tÃcnica para compostos organoclorados. Foram realizados estudos de otimizaÃÃo das condiÃÃes de detecÃÃo dos compostos pelo uso de tÃcnicas de cromatografia gasosa acoplada à espectrometria de massas (GC/MS). Foram identificados compostos farmacÃuticos e desreguladores endÃcrinos em todas as amostras de esgotos com as seguintes faixas de concentraÃÃes efluentes: CAF (3,0-15,8 μg/L), DIP (0,3 μg/L), DCF (1,9 μg/L), DEHP (0,01-8,5μg/L), E1 (0,04-1,7 μg/L), E2 (0,03-4,0 μg/L), EA2 (0,14-9,3 μg/L), EE2 (1,0 μg/L) e COL (0,01-6,2 μg/L). Nos dois corpos receptores estudados (Rio Maranguapinho e Riacho Paupina) foram identificados desreguladores endÃcrinos. Os tratamentos realizados pelas ETEs nÃo foram suficientes para remoÃÃo total de todos os micropoluentes estudados, no entanto, a eficiÃncia para a maioria dos compostos foi acima de 50%. Em se tratando da avaliaÃÃo em sistemas de lagoas de estabilizaÃÃo, o estudo revelou boas eficiÃncias de remoÃÃo em sistemas constituÃdos de lagoa anaerÃbia seguida de facultativa e de maturaÃÃo, sendo os menores valores de remoÃÃo alcanÃados quando uma Ãnica lagoa facultativa primÃria estava presente. A avaliaÃÃo do uso do POA por meio do planejamento fatorial multivariado revelou que as melhores condiÃÃes para remoÃÃo de micropoluentes emergentes foram pH Ãcido (pH 3), concentraÃÃo de perÃxido de hidrogÃnio acima de 400 mg/L e tempos de detenÃÃo hidrÃulica no reator acima de 50min.
In Brazil, studies evaluating emerging micropollutants in environmental matrices such as sewage and hospital wastewater, as well as surface waters,…
Advisors/Committee Members: Ronaldo Ferreira do Nascimento, Francisco SuetÃnio Bastos Mota, Andrà Bezerra dos Santos, Rinaldo dos Santos AraÃjo, Helena Becker, Paula Loureiro Paulo.
Subjects/Keywords: ENGENHARIA CIVIL; Poluentes orgÃnicos; emerging micropollutants, advanced oxidation processes, endocrine disrupting compounds, organochlorine, pharmaceutical residues; Tratamento de Ãguas residuais; Poluentes ambientais; Saneamento
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Souza, N. C. d. (2011). DeterminaÃÃo de Micropoluentes Emergentes em Esgoto SanitÃrio, Hospitalar e Ãguas Superficiais. (Doctoral Dissertation). Universidade Federal do Ceará. Retrieved from http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=7099 ;
Chicago Manual of Style (16th Edition):
Souza, Neyliane Costa de. “DeterminaÃÃo de Micropoluentes Emergentes em Esgoto SanitÃrio, Hospitalar e Ãguas Superficiais.” 2011. Doctoral Dissertation, Universidade Federal do Ceará. Accessed January 27, 2021.
http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=7099 ;.
MLA Handbook (7th Edition):
Souza, Neyliane Costa de. “DeterminaÃÃo de Micropoluentes Emergentes em Esgoto SanitÃrio, Hospitalar e Ãguas Superficiais.” 2011. Web. 27 Jan 2021.
Vancouver:
Souza NCd. DeterminaÃÃo de Micropoluentes Emergentes em Esgoto SanitÃrio, Hospitalar e Ãguas Superficiais. [Internet] [Doctoral dissertation]. Universidade Federal do Ceará 2011. [cited 2021 Jan 27].
Available from: http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=7099 ;.
Council of Science Editors:
Souza NCd. DeterminaÃÃo de Micropoluentes Emergentes em Esgoto SanitÃrio, Hospitalar e Ãguas Superficiais. [Doctoral Dissertation]. Universidade Federal do Ceará 2011. Available from: http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=7099 ;
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