subject:(drusen)

1. Forest, David. Development of Cell Culture Models for Age-related Macular Degeneration.

Degree: 2015, University of California – eScholarship, University of California

URL: http://www.escholarship.org/uc/item/8804x2zv

► Age-related macular degeneration (AMD) is a blinding disorder which affects millions of elderly people worldwide. AMD etiology is still not completely understood, and treatments for… (more)

Subjects/Keywords: Cellular biology; AMD; Cell-culture; Degeneration; Drusen; Macular; Model

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Forest, D. (2015). Development of Cell Culture Models for Age-related Macular Degeneration. (Thesis). University of California – eScholarship, University of California. Retrieved from http://www.escholarship.org/uc/item/8804x2zv

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Forest, David. “Development of Cell Culture Models for Age-related Macular Degeneration.” 2015. Thesis, University of California – eScholarship, University of California. Accessed December 11, 2019. http://www.escholarship.org/uc/item/8804x2zv.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Forest, David. “Development of Cell Culture Models for Age-related Macular Degeneration.” 2015. Web. 11 Dec 2019.

Vancouver:

Forest D. Development of Cell Culture Models for Age-related Macular Degeneration. [Internet] [Thesis]. University of California – eScholarship, University of California; 2015. [cited 2019 Dec 11]. Available from: http://www.escholarship.org/uc/item/8804x2zv.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Forest D. Development of Cell Culture Models for Age-related Macular Degeneration. [Thesis]. University of California – eScholarship, University of California; 2015. Available from: http://www.escholarship.org/uc/item/8804x2zv

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

2. Ueda, Naoko. Macular Choroidal Thickness and Volume of Eyes With Reticular Pseudodrusen Using Swept-Source Optical Coherence Tomography : 波長掃引光源型光干渉断層計を用いたreticular pseudodrusen眼の黄斑部脈絡膜厚および体積の検討.

Degree: 博士(医学), 2016, Kyoto University / 京都大学

URL: http://hdl.handle.net/2433/215412 ; http://dx.doi.org/10.14989/doctor.k19586

Final publication is available at http://www.sciencedirect.com/science/article/pii/S0002939414000488

新制・課程博士

甲第19586号

医博第4093号

Subjects/Keywords: reticular pseudodrusen; choroidal thickness; swept-source optical coherence tomography; age-related macular degeneration; drusen

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Ueda, N. (2016). Macular Choroidal Thickness and Volume of Eyes With Reticular Pseudodrusen Using Swept-Source Optical Coherence Tomography : 波長掃引光源型光干渉断層計を用いたreticular pseudodrusen眼の黄斑部脈絡膜厚および体積の検討. (Thesis). Kyoto University / 京都大学. Retrieved from http://hdl.handle.net/2433/215412 ; http://dx.doi.org/10.14989/doctor.k19586

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Ueda, Naoko. “Macular Choroidal Thickness and Volume of Eyes With Reticular Pseudodrusen Using Swept-Source Optical Coherence Tomography : 波長掃引光源型光干渉断層計を用いたreticular pseudodrusen眼の黄斑部脈絡膜厚および体積の検討.” 2016. Thesis, Kyoto University / 京都大学. Accessed December 11, 2019. http://hdl.handle.net/2433/215412 ; http://dx.doi.org/10.14989/doctor.k19586.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Ueda, Naoko. “Macular Choroidal Thickness and Volume of Eyes With Reticular Pseudodrusen Using Swept-Source Optical Coherence Tomography : 波長掃引光源型光干渉断層計を用いたreticular pseudodrusen眼の黄斑部脈絡膜厚および体積の検討.” 2016. Web. 11 Dec 2019.

Vancouver:

Ueda N. Macular Choroidal Thickness and Volume of Eyes With Reticular Pseudodrusen Using Swept-Source Optical Coherence Tomography : 波長掃引光源型光干渉断層計を用いたreticular pseudodrusen眼の黄斑部脈絡膜厚および体積の検討. [Internet] [Thesis]. Kyoto University / 京都大学; 2016. [cited 2019 Dec 11]. Available from: http://hdl.handle.net/2433/215412 ; http://dx.doi.org/10.14989/doctor.k19586.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Ueda N. Macular Choroidal Thickness and Volume of Eyes With Reticular Pseudodrusen Using Swept-Source Optical Coherence Tomography : 波長掃引光源型光干渉断層計を用いたreticular pseudodrusen眼の黄斑部脈絡膜厚および体積の検討. [Thesis]. Kyoto University / 京都大学; 2016. Available from: http://hdl.handle.net/2433/215412 ; http://dx.doi.org/10.14989/doctor.k19586

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universidade de Lisboa

3. Ventura, Rita Monteiro. Papiledema : um desafio diagnóstico.

Degree: 2017, Universidade de Lisboa

URL: https://www.rcaap.pt/detail.jsp?id=oai:repositorio.ul.pt:10451/35019

►

Trabalho Final do Curso de Mestrado Integrado em Medicina, Faculdade de Medicina, Universidade de Lisboa, 2017

O papiledema é um achado oftalmológico que corresponde a… (more)

Subjects/Keywords: Papiledema; Pseudopapiledema; Drusen do disco ótico; Tomografia de coerência ótica; Oftalmologia; Domínio/Área Científica::Ciências Médicas

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Ventura, R. M. (2017). Papiledema : um desafio diagnóstico. (Thesis). Universidade de Lisboa. Retrieved from https://www.rcaap.pt/detail.jsp?id=oai:repositorio.ul.pt:10451/35019

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Ventura, Rita Monteiro. “Papiledema : um desafio diagnóstico.” 2017. Thesis, Universidade de Lisboa. Accessed December 11, 2019. https://www.rcaap.pt/detail.jsp?id=oai:repositorio.ul.pt:10451/35019.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Ventura, Rita Monteiro. “Papiledema : um desafio diagnóstico.” 2017. Web. 11 Dec 2019.

Vancouver:

Ventura RM. Papiledema : um desafio diagnóstico. [Internet] [Thesis]. Universidade de Lisboa; 2017. [cited 2019 Dec 11]. Available from: https://www.rcaap.pt/detail.jsp?id=oai:repositorio.ul.pt:10451/35019.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Ventura RM. Papiledema : um desafio diagnóstico. [Thesis]. Universidade de Lisboa; 2017. Available from: https://www.rcaap.pt/detail.jsp?id=oai:repositorio.ul.pt:10451/35019

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Southern California

4. Kochounian, Harold H. The exon-skipping variant RGR-d of the human RGR gene: analysis in human retina and cultured cells.

Degree: PhD, Molecular Microbiology & Immunology, 2010, University of Southern California

URL: http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll127/id/605694/rec/6701

► Human retinal pigment epithelial (RPE) cells synthesize an isoform of the RPE-retinal G protein-coupled receptor (RGR). The human RGR gene consists of seven exons and… (more)

▼ Human retinal pigment epithelial (RPE) cells synthesize an isoform of the RPE-retinal G protein-coupled receptor (RGR). The human RGR gene consists of seven exons and the RGR protein is composed of seven transmembrane domains. The RGR opsin is an integral membrane protein that is localized to Müller cells and the apical region of RPE cells, and preferentially binds all-trans retinal. Upon illumination, RGR-bound all-trans retinal is isomerized to 11-cis retinal. RGR functions to maintain normal ocular levels of 11-cis retinal. In contrast to normal RGR, the exon-skipping variant RGR-d lacks the sixth exon in its entirety and the isoform is localized to the basal pole of the RPE.; The RPE basal pole and sub-RPE compartment are strongly associated with age-related changes, such as the accumulation of extracellular deposits. A central hypothesis of this research project is that the disparity in structure and location between RGR and RGR-d infer alternate biological properties. To investigate the implications of the disparities, RGR-d was studied in human retinal tissue and cell cultures.; Analyses of RGR and RGR-d in transfected cells showed that the amount of RGR-d at steady state is significantly lower than that of RGR. In contrast to RGR, the subcellular location of RGR-d in transfected cells mainly sorted to non-smooth endoplasmic reticulum compartments and was observed largely as punctate speckles when examined by confocal microscopy. The intracellular accumulation of RGR-d or fragment of RGR-d, due to the inhibition of exosome formation, and the association of RGR-d with extracellular vesicular deposits in the Bruch’s membrane, support the notion that RGR-d is transported out of the RPE by an exosomic process.; The accumulation of extracellular RGR-d was quite evident in human tissue, and differed noticeably between normal young individuals and older donors with age-related changes in Bruch’s membrane. The concentrated accumulation of RGR-d in the Bruch’s membrane and along the lateral walls of the capillaries was observed in older donors, but was not seen in normal young donors (15-23 yrs of age). The RGR-d epitope was detected in hard, soft, large confluent and early-stage drusen. In addition, localization of RGR-d in the Bruch’s membrane was closely associated with the terminal complement complex C5b-9 and vitronectin. Considering the analysis of RGR-d in extracellular tissue and cultured cells, RGR-d may be a contributing factor in the age-related changes observed in the human eye. Advisors/Committee Members: Fong, Henry (Committee Chair), Cadenas, Enrique (Committee Member), Comai, Lucio (Committee Member), Tahara, Stanley M. (Committee Member).

Subjects/Keywords: RPE; retinal pigment epithelium; Bruch'; s membrane; age-related; RGR, RPE-retinal G protein-coupled receptor; splice variant; RGR-d; drusen

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Kochounian, H. H. (2010). The exon-skipping variant RGR-d of the human RGR gene: analysis in human retina and cultured cells. (Doctoral Dissertation). University of Southern California. Retrieved from http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll127/id/605694/rec/6701

Chicago Manual of Style (16^th Edition):

Kochounian, Harold H. “The exon-skipping variant RGR-d of the human RGR gene: analysis in human retina and cultured cells.” 2010. Doctoral Dissertation, University of Southern California. Accessed December 11, 2019. http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll127/id/605694/rec/6701.

MLA Handbook (7^th Edition):

Kochounian, Harold H. “The exon-skipping variant RGR-d of the human RGR gene: analysis in human retina and cultured cells.” 2010. Web. 11 Dec 2019.

Vancouver:

Kochounian HH. The exon-skipping variant RGR-d of the human RGR gene: analysis in human retina and cultured cells. [Internet] [Doctoral dissertation]. University of Southern California; 2010. [cited 2019 Dec 11]. Available from: http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll127/id/605694/rec/6701.

Council of Science Editors:

Kochounian HH. The exon-skipping variant RGR-d of the human RGR gene: analysis in human retina and cultured cells. [Doctoral Dissertation]. University of Southern California; 2010. Available from: http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll127/id/605694/rec/6701

Freie Universität Berlin

5. Arzheimer, Monique Michèle. analysis of the multifocal electroretinogram.

Degree: 2012, Freie Universität Berlin

URL: http://dx.doi.org/10.17169/refubium-5832

► Hereditary retinopathies represent a heterogenic group of retinal diseases which can have a very different symptomatic complex. Most of the hereditary retinal dystrophies affect the… (more)

▼ Hereditary retinopathies represent a heterogenic group of retinal diseases which can have a very different symptomatic complex. Most of the hereditary retinal dystrophies affect the photoreceptors (rods and cones) and the retinal pigmentary epithelium. Cone diseases result in nocturnal disturbance of vision and losses of the peripheral visual field, rod diseases result in disturbances concerning the colour sense, impaired vision, sensitivity for blinding and losses of the central field. Literature presents a range of publications concerning specific retinal diseases but a comparable survey analysing a great number of different macula- and cone dystrophies by using a constant technology does not exist. The aim of this dissertation is to analyse the clinical validity of the multifocal electroretinogram regarding variability and differential diagnostics of the examination of retinal dystrophies with central dysfunction (= macula- and cone dystrophies). This retrospective survey looks at the clinical history of 186 patients who visited the ophthalmic clinic of the University Hospital Benjamin Franklin in Berlin in the years from 1996 until 2001. 261 of 372 eyes were able to be examined. The reason why only 261 eyes were able to be examined was that the recordings of the multifocal electroretinogram were too artifactual, amongst this blindness of an eye or the certain requests of a patient played a major role. The multifocal electroretinogram is a special method to examine local retinal areas above all macula dystrophies and captures local stimulus responses. The multifocal electroretinogram ia a relatively new electrophysiological method to examine the macula within about seven minutes (without preparation time). With the multifocal electroretinogram rods, cones, ganglion cells and bipolar cells can be stimulated. The purpose of this dissertation was to evaluate the multifocal electroretinogram of every eye. For this purpose curves were activated in a VERIS data bank, the average value of the curves were selected in a circular distance to the fovea and for each of the curves the results for the amplitude of the B-wave P1, for the peak time of the A-wave N1 and for the peak time of the B-wave P1 were acquired. Therefore 15 data were acquired for five curves. The results of the multifocal electroretinogram show partially different functional disorders for the different macula dystrophies. It shows comparing the results of the multifocal electroretinogram of the different macula dystrophies that there can be a distinct discrepancy between morphological and functional changes. Concerning the medical findings we expected that the functional failures were worst of all for the central areolar choroidal dystrophy and for the Stargardt’s disease. Surprisingly there is a minimal functional failure for the hereditary drusen comparing them with the adult vitelliform macula dystrophy although the hereditary drusen affect a much bigger area than only the central fovea. On top of that the kind of functional failure concerning the cone… Advisors/Committee Members: w (gender), Prof. Dr. med. U. Kellner (firstReferee), Prof. Dr. med. A. Joussen (furtherReferee), Prof. Dr. med. H. Helbig (furtherReferee).

Subjects/Keywords: maculadystrophies; multifocal electroretinogram; stargardt's disease; hereditary drusen; cone dystrophy; 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

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APA (6^th Edition):

Arzheimer, M. M. (2012). analysis of the multifocal electroretinogram. (Thesis). Freie Universität Berlin. Retrieved from http://dx.doi.org/10.17169/refubium-5832

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Arzheimer, Monique Michèle. “analysis of the multifocal electroretinogram.” 2012. Thesis, Freie Universität Berlin. Accessed December 11, 2019. http://dx.doi.org/10.17169/refubium-5832.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Arzheimer, Monique Michèle. “analysis of the multifocal electroretinogram.” 2012. Web. 11 Dec 2019.

Vancouver:

Arzheimer MM. analysis of the multifocal electroretinogram. [Internet] [Thesis]. Freie Universität Berlin; 2012. [cited 2019 Dec 11]. Available from: http://dx.doi.org/10.17169/refubium-5832.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Arzheimer MM. analysis of the multifocal electroretinogram. [Thesis]. Freie Universität Berlin; 2012. Available from: http://dx.doi.org/10.17169/refubium-5832

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Houston

6. -6961-1836. Utilization of Orbital Ultrasound and Optical Coherence Tomography in Papilledema and Pseudopapilledema patients.

Degree: Vision Sciences, 2016, University of Houston

URL: http://hdl.handle.net/10657/3548

► Purpose: To evaluate the use of two non-invasive and low-cost tests, orbital ultrasound and optical coherence tomography (OCT), in differentiating papilledema (PE) from pseudopapilledema (PPE).… (more)

▼ Purpose: To evaluate the use of two non-invasive and low-cost tests, orbital ultrasound and optical coherence tomography (OCT), in differentiating papilledema (PE) from pseudopapilledema (PPE). Methods: Retrospective cross-sectional analysis included 51 patients referred to a neuro-ophthalmologist for presumed PE who were diagnosed with PE (n = 23, median Frisen scale II) or PPE (n = 28, 13 buried drusen and 15 obliquely inserted optic nerves) based on a thorough history, ocular/neurological exams and ancillary tests. Orbital ultrasound consisted of a B-scan to detect buried drusen and a standardized A-scan to measure optic nerve sheath diameter (ONSD). If ONSD at primary gaze exceeded normal limits (4.2 mm), a 30° test was performed to measure the ONSD at 30° lateral gaze. A Cirrus OCT Optic Disc Cube 200x200 scan was used to obtain the retinal nerve fiber layer thickness (RNFLT). Results: The mean ONSD (mm) at primary gaze was larger in PE (5.4 ± 0.6) than PPE (4.0 ± 0.3, p < 0.0001). The percent change in the ONSD at 30° gaze was greater in PE (22.4 ± 8.4) than PPE (2.8 ± 4.8, p < 0.0001). Average RNFLT (μm), was thicker in PE (219.1 ± 104.6) than PPE (102.4 ± 20.1, p< 0.0001). ONSD and 30° test had the greatest area under the ROC curve (AUC), 0.98 and 0.97, respectively; followed by inferior quadrant (0.90) and average RNFLT (0.87). In a subgroup of mild PE (Frisen scale I-II, n = 15), AUC remained high for ONSD (0.95) and 30° test (0.93) but decreased to 0.71 for average RNFLT. At 95% specificity, sensitivity (%) for ONSD, 30° test and average RNFLT was 91.3, 91.3 and 56.5, respectively for the entire PE group; 80.0, 86.7 and 13.3 for the mild PE subgroup. Conclusion: Orbital ultrasound and OCT are useful ancillary tests that can be done, along with a thorough examination, to effectively differentiate PE from PPE. Due to its easy access, RNFLT can potentially be used to detect moderate to severe PE. Ultrasound measurements may further assist eye care providers in differentiating mild PE from PPE when ophthalmoscopic findings are non-diagnostic. Advisors/Committee Members: Cheng, Dr. Han (advisor), Tang, Dr. Rosa (committee member), Frishman, Dr. Laura (committee member).

Subjects/Keywords: papilledema; pseudopapilledema; drusen; A scan; B scan; orbital ultrasound; optical coherence tomography; optic nerve sheath diameter; thirty degree test; retinal nerve fiber layer; idiopathic intracranial hypertension; intracranial pressure

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

-6961-1836. (2016). Utilization of Orbital Ultrasound and Optical Coherence Tomography in Papilledema and Pseudopapilledema patients. (Thesis). University of Houston. Retrieved from http://hdl.handle.net/10657/3548

Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

-6961-1836. “Utilization of Orbital Ultrasound and Optical Coherence Tomography in Papilledema and Pseudopapilledema patients.” 2016. Thesis, University of Houston. Accessed December 11, 2019. http://hdl.handle.net/10657/3548.

Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

-6961-1836. “Utilization of Orbital Ultrasound and Optical Coherence Tomography in Papilledema and Pseudopapilledema patients.” 2016. Web. 11 Dec 2019.

Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete

Vancouver:

-6961-1836. Utilization of Orbital Ultrasound and Optical Coherence Tomography in Papilledema and Pseudopapilledema patients. [Internet] [Thesis]. University of Houston; 2016. [cited 2019 Dec 11]. Available from: http://hdl.handle.net/10657/3548.

Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

-6961-1836. Utilization of Orbital Ultrasound and Optical Coherence Tomography in Papilledema and Pseudopapilledema patients. [Thesis]. University of Houston; 2016. Available from: http://hdl.handle.net/10657/3548

Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
Not specified: Masters Thesis or Doctoral Dissertation

University of Southern California

7. Shin, Thuzar Myo. Vitronectin misfolding and aggregation: implications for the pathophysiology of age-related diseases.

Degree: PhD, Pathobiology, 2007, University of Southern California

URL: http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll127/id/521066/rec/7843

► Classic amyloidopathies are characterized by the accumulation of misfolded proteins in the form of plaques. Whilst fibril deposition is pathognomonic for amyloidopathies, recent data suggest… (more)

▼ Classic amyloidopathies are characterized by the accumulation of misfolded proteins in the form of plaques. Whilst fibril deposition is pathognomonic for amyloidopathies, recent data suggest that prefibrillar species may mediate the development and progression of disease. Soluble amyloid oligomers exhibit similar morphologic and cytotoxic properties, suggesting a shared pathogenic mechanism among amyloid proteins. The oligomer-specific A11 antibody is a useful tool to study amyloid diseases which lack abundant fibril deposition. As part of a collaborative study on the pathophysiology of age-related macular degeneration, we studied protein misfolding in human ocular drusen and demonstrated the presence of prefibrillar oligomers using the A11 antibody. However, the oligomer-forming protein in drusen has not yet been identified. Historically, the amyloidogenic protein is oftentimes the most abundant protein near or within the disease plaque. Vitronectin is one of the most abundant drusen proteins, is contained in all drusen, and is also present within the insoluble deposits associated with Alzheimer disease, atherosclerosis, systemic amyloidoses, and glomerulonephritis. These deposits stain positive with thioflavin, indicating an underlying protein misfolding process. The extent to which vitronectin contributes to amyloid formation within these plaques and the role of vitronectin in the pathophysiology of the aforementioned diseases is currently unknown. The investigation of vitronectin misfolding and aggregation is significant since the formation of oligomers and fibrils is a common ability of amyloid proteins, although they share neither sequence nor native structural homology. In this study, we tested the hypothesis that vitronectin is amyloidogenic.; Our results demonstrate that human vitronectin readily forms spherical oligomers and typical amyloid fibrils. Vitronectin oligomers are toxic to cultured cells, possibly via a membrane-dependent mechanism, as they cause leakage of synthetic vesicles. Vitronectin fibrils contain a C-terminal proteaseresistant domain which likely contains the essential residues for amyloid formation. Consistent with our data that illustrate the inherent propensity of vitronectin to selfassociate in vitro, vitronectin fragments were detected in the insoluble fraction of human atherosclerotic plaques, suggesting that vitronectin aggregation likely occurs in vivo. Our results put forth the possibilities that accumulation of misfolded vitronectin may contribute to amyloid plaque formation and the pathophysiology of age-related amyloid diseases. Advisors/Committee Members: Chen, JeannieHinton, David R. (Committee Chair), Langen, Ralf (Committee Member), Triche, Timothy J. (Committee Member), Stallcup, Michael R. (Committee Member).

Subjects/Keywords: drusen; aging; age-related macular degeneration; amyloid; fibril; recombinant protein

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APA (6^th Edition):

Shin, T. M. (2007). Vitronectin misfolding and aggregation: implications for the pathophysiology of age-related diseases. (Doctoral Dissertation). University of Southern California. Retrieved from http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll127/id/521066/rec/7843

Chicago Manual of Style (16^th Edition):

Shin, Thuzar Myo. “Vitronectin misfolding and aggregation: implications for the pathophysiology of age-related diseases.” 2007. Doctoral Dissertation, University of Southern California. Accessed December 11, 2019. http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll127/id/521066/rec/7843.

MLA Handbook (7^th Edition):

Shin, Thuzar Myo. “Vitronectin misfolding and aggregation: implications for the pathophysiology of age-related diseases.” 2007. Web. 11 Dec 2019.

Vancouver:

Shin TM. Vitronectin misfolding and aggregation: implications for the pathophysiology of age-related diseases. [Internet] [Doctoral dissertation]. University of Southern California; 2007. [cited 2019 Dec 11]. Available from: http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll127/id/521066/rec/7843.

Council of Science Editors:

Shin TM. Vitronectin misfolding and aggregation: implications for the pathophysiology of age-related diseases. [Doctoral Dissertation]. University of Southern California; 2007. Available from: http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll127/id/521066/rec/7843

KTH

8. Jönsson, Marthina. Automated methods in the diagnosing of retinal images.

Degree: Systems Safety and Management, 2012, KTH

URL: http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-122721

►

This report contains a summation of a variety of articles that have been read and analysed. Each article describes different methods that can be… (more)

▼

This report contains a summation of a variety of articles that have been read and analysed. Each article describes different methods that can be used to detect lesions, optic disks, drusen and exudates in retinal images. I.e. diagnose e.g. Diabetic Retinopathy and Age-Related Macular Degeneration. A general approach is presented, which all methods more or less is based on. Methods to locate the optic disk The PCA kNN Regression Hough Transform Fuzzy Convergence Vessel Direction Matched Filter Etc. The best method based on result, reliability, number of images and publisher is kNN regression. The result of this method is remarkably good and that brings some doubt about its reliability. Though the method was published at IEEE and that gives the method a more trustful look. A next best method which also is very useful is Vessel Direction Matched Filter. Methods to detect drusen – diagnose Age-Related Macular Degeneration PNN classifier Histogram approach Etc. The best method based on result, reliability, number of images and publisher is the PNN classifier. The method had a sensitivity of 94 % and a specificity of 95 %. 300 images were used in the experiment which was published by the IEEE in 2011. Methods to detect exudates – diagnose Diabetic Retinopathy Morphological techniquesLuv colour space, Wiener filter an Canny edge detector. The best method based on result, reliability, number of images and publisher is an experiment called “Feature Extraction”. The method includes the Luv colour space, Wiener filter (remove noise) and the Canny edge detector.

Den här rapporten innehåller en sammanfattning av ett flertal artiklar som har blivit studerade. Varje artikel har beskrivit en metod som kan användas för att upptäcka sjuka förändringar i ögonbottenbilder, det vill säga, åldersförändringar i gula fläcken och diabetisk retinopati. Metoder för att lokalisera blinda fläcken PCAkNN regressionHough omvandlingSuddig konvergensFiltrering beroende på kärlens riktningMm. Den bästa metoden baserat på resultat, pålitlighet, antal bilder och utgivare är kNN regression. De förvånansvärt goda resultaten kan inbringa lite tvivel på huruvida resultaten stämmer. Artikeln publicerades dock av IEEE och det gör artikeln mer trovärdig. Den näst bästa metoden är filtrering beroende på kärlens riktning. Metoder för att diagnosticera åldersförändringar i gula fläcken PNN klassificerarenHistogramMm. Den bästa metoden baserat på resultat, pålitlighet, antal bilder och utgivare är PNN klassificeraren. Metoden hade en…

Subjects/Keywords: retina; fundus; automatic; automated; analysis; image; optic disk; macula; agerelated macular degeneration; drusen; diabetic retinopathy and diagnoses.; Medical Image Processing; Medicinsk bildbehandling

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Jönsson, M. (2012). Automated methods in the diagnosing of retinal images. (Thesis). KTH. Retrieved from http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-122721

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Jönsson, Marthina. “Automated methods in the diagnosing of retinal images.” 2012. Thesis, KTH. Accessed December 11, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-122721.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Jönsson, Marthina. “Automated methods in the diagnosing of retinal images.” 2012. Web. 11 Dec 2019.

Vancouver:

Jönsson M. Automated methods in the diagnosing of retinal images. [Internet] [Thesis]. KTH; 2012. [cited 2019 Dec 11]. Available from: http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-122721.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Jönsson M. Automated methods in the diagnosing of retinal images. [Thesis]. KTH; 2012. Available from: http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-122721

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Kyoto University

9. Ueda, Naoko. Macular Choroidal Thickness and Volume of Eyes With Reticular Pseudodrusen Using Swept-Source Optical Coherence Tomography .

Degree: 2016, Kyoto University

URL: http://hdl.handle.net/2433/215412

Subjects/Keywords: reticular pseudodrusen; choroidal thickness; swept-source optical coherence tomography; age-related macular degeneration; drusen

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Ueda, N. (2016). Macular Choroidal Thickness and Volume of Eyes With Reticular Pseudodrusen Using Swept-Source Optical Coherence Tomography . (Thesis). Kyoto University. Retrieved from http://hdl.handle.net/2433/215412

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Ueda, Naoko. “Macular Choroidal Thickness and Volume of Eyes With Reticular Pseudodrusen Using Swept-Source Optical Coherence Tomography .” 2016. Thesis, Kyoto University. Accessed December 11, 2019. http://hdl.handle.net/2433/215412.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Ueda, Naoko. “Macular Choroidal Thickness and Volume of Eyes With Reticular Pseudodrusen Using Swept-Source Optical Coherence Tomography .” 2016. Web. 11 Dec 2019.

Vancouver:

Ueda N. Macular Choroidal Thickness and Volume of Eyes With Reticular Pseudodrusen Using Swept-Source Optical Coherence Tomography . [Internet] [Thesis]. Kyoto University; 2016. [cited 2019 Dec 11]. Available from: http://hdl.handle.net/2433/215412.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Ueda N. Macular Choroidal Thickness and Volume of Eyes With Reticular Pseudodrusen Using Swept-Source Optical Coherence Tomography . [Thesis]. Kyoto University; 2016. Available from: http://hdl.handle.net/2433/215412

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Luleå University of Technology

10. Lundkvist, Stefan. OCT (Optical Coherense Tomography) : Teknik och tillämpning.

Degree: 2013, Luleå University of Technology

URL: http://urn.kb.se/resolve?urn=urn:nbn:se:ltu:diva-52886

► Before year 1895, the doctors could only make a probable diagnosis based on what the patient could tell and it was hurt and there… (more)

▼ Before year 1895, the doctors could only make a probable diagnosis based on what the patient could tell and it was hurt and there was no discernable change to the outside of the body. With X-ray, it was possible to see inside the patient without first cutting it, you can say that the X-ray was the starting point for diagnostic imaging.The further development of X-ray gave CT (Computed Tomography), where X-ray tubes and detectors rotate around the patient while the patient table moves. Besides CT also developed MRI (Magnetic Resonance Imaging), PET (Positron Emission Tomography) and Ultrasound. Common to these methods is that the produced 3D images.In 1990 a completely new approach for diagnostic imaging, OCT (optical coherence tomography), by measuring the phase shift and the intensity of reflected light, it provides real-time and non-destructive measurements (in vivo) a resolution of 1 to 15 microns, much higher than all other standard imaging techniques. You could say that OCT machine can be compared to ultrasound, which uses the reflection of sound waves to interpretation.The first OCT machines were of type TD (Time Domain), these had low resolution and low scanning speed. In 2005 came the SD-OCT, they had higher resolution and scanning speed, SD stands for spectral domain, SD-OCT is sometimes called FD-OCT as Fourier transformed signals and operating in the frequency domain.The development of OCT machines are only in their infancy, resolution, scanning speed and accuracy will increase all the time, this allows new uses and ways to diagnose developed. OCT can be used in such Oncology, MSD (Musculoskeletal disorders), cardiovascular medicine, teeth, nerves, but the largest field is the eye and then the back of the eye called the retina (retina).This thesis is limited to the eye, the purpose is to provide input to those who are likely to purchase an OCT-machine, but also show the measurement data OCT-machines are performing and how to use the OCT-machine more than to see age-related macular degeneration. Another aim is to increase understanding of the physics behind an OCT-machine for ease of understanding the output given.The manufacture/model that have selected for evaluation are Zeiss Cirrus 4000, Topcon 3D OCT-2000 and Heidelberg Spectralis, the reason is that there are only these three on the Swedish market and all are SD-OCT. The way to evaluate OCT-machines is to scan performance and what the various analysis programs can handle. Furthermore, each OCT-machine scans the macula and optic disk on a experimental person/ reference eye, in order to get the output of the precision, or if you want to call it repeatability, which is very important if one wants to follow a solitary disease course.The conclusion of this thesis is to OCT machines are quite similar. When it comes to ease of use when doing scans is the Cirrus is lightened by the use of the extra screen where you always look eye (iris camera), which makes it easy to adjust the sharpness and position of the mouse buttons. Topcon and Heidelberg is not…

Subjects/Keywords: Technology; Teknik; OCT; optical choerence tomography; Retina; Makula; Macula; RNFL; Bruchs membran; AMD; våt-AMD; drusen; Lipider; Angiografi; näthinnan; hornhinnan; Fundus; A-scan; Anterior segement; Cornea; Kammarvinkeln; Optic disc; Blinda fläcken; fovea; ICG; Tropocamide; Glaukom; Zeiss Cirrus 4000; Topcon 3D OCT-2000; Heidelberg Spectralis; anti-VEGF; VEGF

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Lundkvist, S. (2013). OCT (Optical Coherense Tomography) : Teknik och tillämpning. (Thesis). Luleå University of Technology. Retrieved from http://urn.kb.se/resolve?urn=urn:nbn:se:ltu:diva-52886

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Lundkvist, Stefan. “OCT (Optical Coherense Tomography) : Teknik och tillämpning.” 2013. Thesis, Luleå University of Technology. Accessed December 11, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:ltu:diva-52886.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Lundkvist, Stefan. “OCT (Optical Coherense Tomography) : Teknik och tillämpning.” 2013. Web. 11 Dec 2019.

Vancouver:

Lundkvist S. OCT (Optical Coherense Tomography) : Teknik och tillämpning. [Internet] [Thesis]. Luleå University of Technology; 2013. [cited 2019 Dec 11]. Available from: http://urn.kb.se/resolve?urn=urn:nbn:se:ltu:diva-52886.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Lundkvist S. OCT (Optical Coherense Tomography) : Teknik och tillämpning. [Thesis]. Luleå University of Technology; 2013. Available from: http://urn.kb.se/resolve?urn=urn:nbn:se:ltu:diva-52886

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Brno University of Technology

11. Stančíková, Ivana. Detekce a rozpoznání projevů onemocnění VPMD na sítnici lidského oka .

Degree: 2019, Brno University of Technology

URL: http://hdl.handle.net/11012/180117

► Cílem této bakalářské práce je vytvoření nástroje pro detekci příznaků onemocnění věkem podmíněnou makulární degenerací na snímcích sítnice lidského oka. Toto onemocnění patří k nejčastějším… (more)

Subjects/Keywords: věkem podmíněná makulární degenerace; VPMD; lidské oko; sítnice; onemocnění oka; drúzy; detekce; zpracování obrazu; C++; OpenCV; age-related macular degeneration; ARMD; human eye; retina; eye diseases; drusen; detection; image processing; C++; OpenCV

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Stančíková, I. (2019). Detekce a rozpoznání projevů onemocnění VPMD na sítnici lidského oka . (Thesis). Brno University of Technology. Retrieved from http://hdl.handle.net/11012/180117

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Stančíková, Ivana. “Detekce a rozpoznání projevů onemocnění VPMD na sítnici lidského oka .” 2019. Thesis, Brno University of Technology. Accessed December 11, 2019. http://hdl.handle.net/11012/180117.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Stančíková, Ivana. “Detekce a rozpoznání projevů onemocnění VPMD na sítnici lidského oka .” 2019. Web. 11 Dec 2019.

Vancouver:

Stančíková I. Detekce a rozpoznání projevů onemocnění VPMD na sítnici lidského oka . [Internet] [Thesis]. Brno University of Technology; 2019. [cited 2019 Dec 11]. Available from: http://hdl.handle.net/11012/180117.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Stančíková I. Detekce a rozpoznání projevů onemocnění VPMD na sítnici lidského oka . [Thesis]. Brno University of Technology; 2019. Available from: http://hdl.handle.net/11012/180117

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Florida

12. Seo,Soo Jung. Generation of Age-Related Macular Degeneration Mouse Model by Induction of Oxidative Stress.

Degree: PhD, Medical Sciences - Genetics (IDP), 2011, University of Florida

URL: http://ufdc.ufl.edu/UFE0043263

Subjects/Keywords: Animal models; Drusen; Gene therapy; Macular degeneration; Mice; Oxidative stress; Photoreceptors; Retina; Sand sheets; Superoxides; amd; degeneration; genetic; macular; model; mouse; ribozymes; ros

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Jung, S. (2011). Generation of Age-Related Macular Degeneration Mouse Model by Induction of Oxidative Stress. (Doctoral Dissertation). University of Florida. Retrieved from http://ufdc.ufl.edu/UFE0043263

Chicago Manual of Style (16^th Edition):

Jung, Seo,Soo. “Generation of Age-Related Macular Degeneration Mouse Model by Induction of Oxidative Stress.” 2011. Doctoral Dissertation, University of Florida. Accessed December 11, 2019. http://ufdc.ufl.edu/UFE0043263.

MLA Handbook (7^th Edition):

Jung, Seo,Soo. “Generation of Age-Related Macular Degeneration Mouse Model by Induction of Oxidative Stress.” 2011. Web. 11 Dec 2019.

Vancouver:

Jung S. Generation of Age-Related Macular Degeneration Mouse Model by Induction of Oxidative Stress. [Internet] [Doctoral dissertation]. University of Florida; 2011. [cited 2019 Dec 11]. Available from: http://ufdc.ufl.edu/UFE0043263.

Council of Science Editors:

Jung S. Generation of Age-Related Macular Degeneration Mouse Model by Induction of Oxidative Stress. [Doctoral Dissertation]. University of Florida; 2011. Available from: http://ufdc.ufl.edu/UFE0043263

University of Sydney

13. Cherepanoff, Svetlana. Age-related macular degeneration: histopathological and serum autoantibody studies .

Degree: 2007, University of Sydney

URL: http://hdl.handle.net/2123/2464

► BACKGROUND: The accumulation of abnormal extracellular deposits beneath the retinal pigment epithelium characterises the pathology of early age-related macular degeneration. However, the histopathological threshold at… (more)

▼ BACKGROUND: The accumulation of abnormal extracellular deposits beneath the retinal pigment epithelium characterises the pathology of early age-related macular degeneration. However, the histopathological threshold at which age-related changes become early AMD is not defined, and the effect of each of the deposits (basal laminar deposit and membranous debris) on disease progression is poorly understood. Evidence suggests that macrophages play a key role in the development of AMD lesions, but the influence of basal laminar deposit (BLamD) and membranous debris on the recruitment and programming of local macrophages has not been explored. Although evidence also suggests that inflammation and innate immunity are involved in AMD, the significance of anti-retinal autoantibodies to disesase pathogenesis is not known. AIMS: (i) To determine the histopathological threshold that distinguishes normal ageing from early AMD; (ii) to determine the influence of BLamD and membranous debris on disease progression; (iii) to examine whether distinct early AMD phenotypes exist based on clinicopathological evidence; (iv) to determine the histopathological context in which Bruch’s membrane macrophages first found; (v) to examine the relationship between Bruch’s membrane macrophages and subclinical neovascularisation; (vi) to determine if the progressive accumulation of BLamD and membranous debris alters the immunophenotype of Bruch’s membrane macrophages and/or resident choroidal macrophages; (vii) to determine if the anti-retinal autoantibody profile differs significantly between normal individuals and those with early AMD, neovascular AMD or geographic atrophy; (viii) to examine whether baseline anti-retinal autoantibodies can predict progression to advanced AMD in individuals with early AMD; and (ix) to examine whether baseline anti-retinal autoantibodies can predict vision loss in individuals with neovascular AMD. METHODS:Clinicopathological studies were performed to correlate progressive accumulation of BLamD and membranous debris to fundus characteristics and visual acuity, as well as to sub-macular Bruch’s membrane macrophage count. Immunohistochemical studies were perfomed to determine whether the presence of BLamD and membranous debris altered the programming of Bruch’s membrane or resident choroidal macrophages. The presence of serum anti-retinal autoantibodies was determined by western blotting, and the association with disease progression examined in early and neovascular AMD. RESULTS: The presence of both basal linear deposit (BLinD) and a continuous layer of BLamD represents threshold early AMD histopathologically, which was seen clinically as a normal fundus in the majority of cases. Membranous debris accumulation appeared to influence the pathway of progression from early AMD to advanced AMD. Bruch’s membrane macrophages were first noted when a continuous layer of BLamD and clinical evidence of early AMD were present, and increased with the amount of membranous debris in eyes with thin BLamD. Eyes with…

Subjects/Keywords: age-related macular degeneration; Bruch's membrane; drusen; basal deposits; basal laminar deposit; basal linear deposit; macrophages; anti-retinal autoantibodies; neovascularisation; disciform scar; geographic atrophy; blindness

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Cherepanoff, S. (2007). Age-related macular degeneration: histopathological and serum autoantibody studies . (Thesis). University of Sydney. Retrieved from http://hdl.handle.net/2123/2464

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Cherepanoff, Svetlana. “Age-related macular degeneration: histopathological and serum autoantibody studies .” 2007. Thesis, University of Sydney. Accessed December 11, 2019. http://hdl.handle.net/2123/2464.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Cherepanoff, Svetlana. “Age-related macular degeneration: histopathological and serum autoantibody studies .” 2007. Web. 11 Dec 2019.

Vancouver:

Cherepanoff S. Age-related macular degeneration: histopathological and serum autoantibody studies . [Internet] [Thesis]. University of Sydney; 2007. [cited 2019 Dec 11]. Available from: http://hdl.handle.net/2123/2464.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Cherepanoff S. Age-related macular degeneration: histopathological and serum autoantibody studies . [Thesis]. University of Sydney; 2007. Available from: http://hdl.handle.net/2123/2464

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Université de Montréal

14. Murphy, Caitlin. The Visual Impairment/Cognitive Impairment Co-morbidity : Examining the Genotype-Structure-Function Relationship .

Degree: 2018, Université de Montréal

URL: http://hdl.handle.net/1866/19986

Subjects/Keywords: Age-related Macular Degeneration (AMD); Alzheimer’s Disease (AD); Mild Cognitive Impairment (MCI); Complement Factor H (CFH); Age-related Maculopathy Susceptibility Gene 2 (ARMS2); Fatty Acid Desaturase 1 (FADS1); Single nucleotide polymorphism (SNP); Drusen; Retina; Visual function; La dégénérescence maculaire liée à l'âge (DMLA); la maladie d'Alzheimer (AD); la déficience cognitive légère; le facteur de complément H (CFH); la susceptibilité à la maculopathie liée à l'âge 2 (ARMS2); la désaturase acide gras 1 (FADS1); le nucléotide unique polymorphisme (SNP); fonction visuelle

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Murphy, C. (2018). The Visual Impairment/Cognitive Impairment Co-morbidity : Examining the Genotype-Structure-Function Relationship . (Thesis). Université de Montréal. Retrieved from http://hdl.handle.net/1866/19986

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Murphy, Caitlin. “The Visual Impairment/Cognitive Impairment Co-morbidity : Examining the Genotype-Structure-Function Relationship .” 2018. Thesis, Université de Montréal. Accessed December 11, 2019. http://hdl.handle.net/1866/19986.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Murphy, Caitlin. “The Visual Impairment/Cognitive Impairment Co-morbidity : Examining the Genotype-Structure-Function Relationship .” 2018. Web. 11 Dec 2019.

Vancouver:

Murphy C. The Visual Impairment/Cognitive Impairment Co-morbidity : Examining the Genotype-Structure-Function Relationship . [Internet] [Thesis]. Université de Montréal; 2018. [cited 2019 Dec 11]. Available from: http://hdl.handle.net/1866/19986.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Murphy C. The Visual Impairment/Cognitive Impairment Co-morbidity : Examining the Genotype-Structure-Function Relationship . [Thesis]. Université de Montréal; 2018. Available from: http://hdl.handle.net/1866/19986

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

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Open Access Theses and Dissertations