subject:(diagnostics)

1. Angione, Stephanie L. Microfluidic Platforms for Molecular Diagnostics and Developmental Biology.

Degree: PhD, Biomedical Engineering, 2014, Brown University

URL: https://repository.library.brown.edu/studio/item/bdr:386202/

► Microfluidic technology provides a means of precisely controlling fluid flow for molecular analytics and diagnostics, as well for the biological analysis of cells and small… (more)

Subjects/Keywords: molecular diagnostics

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APA (6^th Edition):

Angione, S. L. (2014). Microfluidic Platforms for Molecular Diagnostics and Developmental Biology. (Doctoral Dissertation). Brown University. Retrieved from https://repository.library.brown.edu/studio/item/bdr:386202/

Chicago Manual of Style (16^th Edition):

Angione, Stephanie L. “Microfluidic Platforms for Molecular Diagnostics and Developmental Biology.” 2014. Doctoral Dissertation, Brown University. Accessed January 17, 2021. https://repository.library.brown.edu/studio/item/bdr:386202/.

MLA Handbook (7^th Edition):

Angione, Stephanie L. “Microfluidic Platforms for Molecular Diagnostics and Developmental Biology.” 2014. Web. 17 Jan 2021.

Vancouver:

Angione SL. Microfluidic Platforms for Molecular Diagnostics and Developmental Biology. [Internet] [Doctoral dissertation]. Brown University; 2014. [cited 2021 Jan 17]. Available from: https://repository.library.brown.edu/studio/item/bdr:386202/.

Council of Science Editors:

Angione SL. Microfluidic Platforms for Molecular Diagnostics and Developmental Biology. [Doctoral Dissertation]. Brown University; 2014. Available from: https://repository.library.brown.edu/studio/item/bdr:386202/

University of Debrecen

2. Patel, Suniti. Exosomal Transport and Salivary Diagnostics .

Degree: DE – Fogorvostudományi Kar, University of Debrecen

URL: http://hdl.handle.net/2437/240951

A brief insight into exosomes, their functions, uses and diagnostics. Advisors/Committee Members: Tar, Ildikó (advisor), Debreceni Egyetem::Fogorvostudományi Kar (advisor).

Subjects/Keywords: Diagnostics

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APA (6^th Edition):

Patel, S. (n.d.). Exosomal Transport and Salivary Diagnostics . (Thesis). University of Debrecen. Retrieved from http://hdl.handle.net/2437/240951

Note: this citation may be lacking information needed for this citation format:
No year of publication.
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Patel, Suniti. “Exosomal Transport and Salivary Diagnostics .” Thesis, University of Debrecen. Accessed January 17, 2021. http://hdl.handle.net/2437/240951.

Note: this citation may be lacking information needed for this citation format:
No year of publication.
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Patel, Suniti. “Exosomal Transport and Salivary Diagnostics .” Web. 17 Jan 2021.

Note: this citation may be lacking information needed for this citation format:
No year of publication.

Vancouver:

Patel S. Exosomal Transport and Salivary Diagnostics . [Internet] [Thesis]. University of Debrecen; [cited 2021 Jan 17]. Available from: http://hdl.handle.net/2437/240951.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
No year of publication.

Council of Science Editors:

Patel S. Exosomal Transport and Salivary Diagnostics . [Thesis]. University of Debrecen; Available from: http://hdl.handle.net/2437/240951

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
No year of publication.

Cornell University

3. Mancuso, Matthew. Nanotechnology And Smartphones Enable Better Point Of Care Diagnostics For Kaposi’S Sarcoma Herpesvirus Dna.

Degree: PhD, Biomedical Engineering, 2014, Cornell University

URL: http://hdl.handle.net/1813/37110

► In order to provide improved and more personalized medical care, better diagnosis and quantification of different biomarkers is necessary. During the tenure of my PhD… (more)

Subjects/Keywords: Nanotechnology; Diagnostics; Smartphones

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APA (6^th Edition):

Mancuso, M. (2014). Nanotechnology And Smartphones Enable Better Point Of Care Diagnostics For Kaposi’S Sarcoma Herpesvirus Dna. (Doctoral Dissertation). Cornell University. Retrieved from http://hdl.handle.net/1813/37110

Chicago Manual of Style (16^th Edition):

Mancuso, Matthew. “Nanotechnology And Smartphones Enable Better Point Of Care Diagnostics For Kaposi’S Sarcoma Herpesvirus Dna.” 2014. Doctoral Dissertation, Cornell University. Accessed January 17, 2021. http://hdl.handle.net/1813/37110.

MLA Handbook (7^th Edition):

Mancuso, Matthew. “Nanotechnology And Smartphones Enable Better Point Of Care Diagnostics For Kaposi’S Sarcoma Herpesvirus Dna.” 2014. Web. 17 Jan 2021.

Vancouver:

Mancuso M. Nanotechnology And Smartphones Enable Better Point Of Care Diagnostics For Kaposi’S Sarcoma Herpesvirus Dna. [Internet] [Doctoral dissertation]. Cornell University; 2014. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1813/37110.

Council of Science Editors:

Mancuso M. Nanotechnology And Smartphones Enable Better Point Of Care Diagnostics For Kaposi’S Sarcoma Herpesvirus Dna. [Doctoral Dissertation]. Cornell University; 2014. Available from: http://hdl.handle.net/1813/37110

4. Mouton, Thomas. Analyse des processus de nucléation et de croissance des particules de suie dans des flammes par fluorescence induite par laser en jet froid appliquée aux hydrocarbures aromatiques polycycliques et par incandescence induite par laser : Analysis of nucleation and growth processes of soot particles in flames by laser induced fluorescence applied to polycyclic aromatic hydrocarbons and by laser induced incandescence.

Degree: Docteur es, Optique et Lasers, Physico-Chimie, Atmosphère, 2014, Université Lille I – Sciences et Technologies

URL: http://www.theses.fr/2014LIL10150

►

Les particules de suie émises lors de la combustion d’hydrocarbures ont un impact important sur le réchauffement climatique et sur la santé. La compréhension des… (more)

▼

Les particules de suie émises lors de la combustion d’hydrocarbures ont un impact important sur le réchauffement climatique et sur la santé. La compréhension des mécanismes de formation des particules de suie dans les flammes présente donc un fort intérêt environnemental. Cependant, le mécanisme de formation de ces particules pose toujours de nombreuses questions. En particulier la phase de nucléation, qui conduit à la formation des particules primaires de suie (nuclei) à partir de molécules HAPs (Hydrocarbures Aromatiques Polycycliques) en phase gazeuse, reste incomprise. Au cours de ce travail de thèse, nous avons mis en œuvre deux méthodes expérimentales de diagnostic laser, la Fluorescence Induite par Laser en Jet Froid (JCLIF) et l’Incandescence Induite par Laser (LII), respectivement pour la mesure de HAPs (naphtalène, pyrène et fluoranthène) et des particules de suies formées dans des flammes de CH4/O2/N2 stabilisées à basse-pression et de C2H4/air stabilisées à pression atmosphérique. Les résultats obtenus offrent une base de données expérimentale tout à fait originale pour l’amélioration de la compréhension des voies réactionnelles prépondérantes menant à la formation des particules de suie. Par ailleurs, nous avons également mis en évidence l’existence de flammes de nucléation, i.e des flammes dans lesquelles les particules de suie sont essentiellement formées par nucléation, sans subir de croissance de surface. Dans ce travail de thèse, nous montrons que ces flammes pourraient ainsi constituer un cas test unique et très pertinent pour la compréhension du processus de nucléation.

Soot particles emitted during fuel combustion have an important impact on global warming and health. Therefore, the improvement of the knowledge on soot particle formation mechanisms in flames shows an important environmental interest. However, this mechanism is not fully understood. Indeed, the nucleation step, forming primary particles (nuclei) from gaseous PAHs (Polycyclic Aromatic Hydrocarbons), is still speculative and needs accurate experimental data to be fully understood. In this work, two experimental techniques based on laser diagnostics have been implemented, the Jet-Cooled Laser Induced Fluorescence (JCLIF) and the Laser Induced Incandescence (LII), respectively for the measurement of PAHs (naphthalene, pyrene and fluoranthene) and soot particles formed in low-pressure CH4/O2/N2 flames and atmospheric pressure C2H4/air flames. These results offer an original experimental database for the improvement of the understanding of the main chemical pathways leading to soot particle formation. Besides, we also highlight the possibility of generating nucleation flames, i.e flames in which soot particles are essentially formed by nucleation, without growth by soot surface processes. In this thesis, we show that these specific flame conditions could be a unique test case, very well suited for the understanding of the soot nucleation process.

Advisors/Committee Members: Desgroux, Pascale (thesis director), Mercier, Xavier (thesis director).

Subjects/Keywords: Diagnostics laser; 541.361

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APA (6^th Edition):

Mouton, T. (2014). Analyse des processus de nucléation et de croissance des particules de suie dans des flammes par fluorescence induite par laser en jet froid appliquée aux hydrocarbures aromatiques polycycliques et par incandescence induite par laser : Analysis of nucleation and growth processes of soot particles in flames by laser induced fluorescence applied to polycyclic aromatic hydrocarbons and by laser induced incandescence. (Doctoral Dissertation). Université Lille I – Sciences et Technologies. Retrieved from http://www.theses.fr/2014LIL10150

Chicago Manual of Style (16^th Edition):

Mouton, Thomas. “Analyse des processus de nucléation et de croissance des particules de suie dans des flammes par fluorescence induite par laser en jet froid appliquée aux hydrocarbures aromatiques polycycliques et par incandescence induite par laser : Analysis of nucleation and growth processes of soot particles in flames by laser induced fluorescence applied to polycyclic aromatic hydrocarbons and by laser induced incandescence.” 2014. Doctoral Dissertation, Université Lille I – Sciences et Technologies. Accessed January 17, 2021. http://www.theses.fr/2014LIL10150.

MLA Handbook (7^th Edition):

Mouton, Thomas. “Analyse des processus de nucléation et de croissance des particules de suie dans des flammes par fluorescence induite par laser en jet froid appliquée aux hydrocarbures aromatiques polycycliques et par incandescence induite par laser : Analysis of nucleation and growth processes of soot particles in flames by laser induced fluorescence applied to polycyclic aromatic hydrocarbons and by laser induced incandescence.” 2014. Web. 17 Jan 2021.

Vancouver:

Mouton T. Analyse des processus de nucléation et de croissance des particules de suie dans des flammes par fluorescence induite par laser en jet froid appliquée aux hydrocarbures aromatiques polycycliques et par incandescence induite par laser : Analysis of nucleation and growth processes of soot particles in flames by laser induced fluorescence applied to polycyclic aromatic hydrocarbons and by laser induced incandescence. [Internet] [Doctoral dissertation]. Université Lille I – Sciences et Technologies; 2014. [cited 2021 Jan 17]. Available from: http://www.theses.fr/2014LIL10150.

Council of Science Editors:

Mouton T. Analyse des processus de nucléation et de croissance des particules de suie dans des flammes par fluorescence induite par laser en jet froid appliquée aux hydrocarbures aromatiques polycycliques et par incandescence induite par laser : Analysis of nucleation and growth processes of soot particles in flames by laser induced fluorescence applied to polycyclic aromatic hydrocarbons and by laser induced incandescence. [Doctoral Dissertation]. Université Lille I – Sciences et Technologies; 2014. Available from: http://www.theses.fr/2014LIL10150

University of Victoria

5. Smith, Brenden Charles. The development of novel antigens for improved syphilis diagnosis.

Degree: Dept. of Biochemistry and Microbiology, 2012, University of Victoria

URL: http://hdl.handle.net/1828/4043

► Syphilis is a disease caused by the bacterium Treponema pallidum subsp. pallidum, which is generally transmitted through sexual contact, or vertically from a mother to… (more)

▼ Syphilis is a disease caused by the bacterium Treponema pallidum subsp. pallidum, which is generally transmitted through sexual contact, or vertically from a mother to her fetus. Syphilis is effectively treated with penicillin yet remains prevalent worldwide, due in part to the shortfalls of current diagnostic tests. Traditional serological testing algorithms screen with diagnostic tests specific for non-treponemal antibodies followed by subsequent screening of reactive samples for treponeme-specific antibodies. Limitations exist with both the sensitivity and specificity of non-treponemal and treponemal tests. Specific enzyme immunoassays, chemiluminescence assays and rapid point-of-care tests have been developed that contain the T. pallidum proteins TpN15 (Tp0171), TpN17 (Tp0435), TpN47 (Tp0574), and/or TpN44 (Tp0768; TmpA). These tests have also been shown to have suboptimal sensitivities, highlighting the need for identification of novel syphilis diagnostic candidates. In this study, soluble recombinant versions of two previously identified diagnostic candidates, Tp0326 and Tp0453, as well as a novel Tp0453-Tp0326 chimera were produced. The sensitivity of these recombinant proteins in enzyme-linked immunosorbant assays (ELISA) for diagnosis of syphilis was determined by screening characterized serum samples from primary, secondary, and latent stages of infection (n=169). The specificity was determined by screening uninfected individuals (n=13), false positives identified via the standard testing algorithm (n=19), and potentially cross-reactive infections caused by Leptospira, B. burgdorferi, H. pylori, Epstein-Barr virus, hepatitis B virus, hepatitis C virus, and cytomegalovirus (n=38). The sensitivities for Tp0326, Tp0453, and the Tp0453-Tp0326 chimera were found to be 86%, 98% and 98%, respectively. The specificities for Tp0326, Tp0453, and the Tp0453-Tp0326 chimera were found to be 99%, 100% and 99%, respectively. These findings suggest that Tp0453 and the Tp0453-Tp0326 chimera show promise as novel syphilis-specific diagnostic candidates for accurate detection of all stages of infection and for future development into numerous diagnostic test formats including enzyme immunoassays, chemiluminescence assays, and rapid point-of-care tests. Advisors/Committee Members: Cameron, Caroline E. (supervisor).

Subjects/Keywords: Diagnostics; Microbiology; Syphilis

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APA (6^th Edition):

Smith, B. C. (2012). The development of novel antigens for improved syphilis diagnosis. (Masters Thesis). University of Victoria. Retrieved from http://hdl.handle.net/1828/4043

Chicago Manual of Style (16^th Edition):

Smith, Brenden Charles. “The development of novel antigens for improved syphilis diagnosis.” 2012. Masters Thesis, University of Victoria. Accessed January 17, 2021. http://hdl.handle.net/1828/4043.

MLA Handbook (7^th Edition):

Smith, Brenden Charles. “The development of novel antigens for improved syphilis diagnosis.” 2012. Web. 17 Jan 2021.

Vancouver:

Smith BC. The development of novel antigens for improved syphilis diagnosis. [Internet] [Masters thesis]. University of Victoria; 2012. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1828/4043.

Council of Science Editors:

Smith BC. The development of novel antigens for improved syphilis diagnosis. [Masters Thesis]. University of Victoria; 2012. Available from: http://hdl.handle.net/1828/4043

University of Illinois – Urbana-Champaign

6. Hammack, Stephen Daniel. Development of high-speed laser diagnostics for the study of advanced propulsion systems.

Degree: PhD, Mechanical Engineering, 2015, University of Illinois – Urbana-Champaign

URL: http://hdl.handle.net/2142/89121

► Combustion in next-generation high-speed propulsion systems involves highly turbulent reactive flow conditions, often beyond the limits of our physicochemical understanding. It is a challenge to… (more)

▼ Combustion in next-generation high-speed propulsion systems involves highly turbulent reactive flow conditions, often beyond the limits of our physicochemical understanding. It is a challenge to produce reliable combustion as localized extinction and instabilities are highly transient in nature. It is in this effort that the progressing capabilities of laser diagnostics open new possibilities of exploring the chemistry and fluid dynamics of complex reacting flows. The primary objective of this study is to develop and apply kHz-rate planar imaging to further our understanding of ignition and flame dynamics in turbulent flames relevant to next-generation propulsion systems. High-repetition-rate planar laser-induced fluorescence (PLIF) is used to produce temporally resolved two-dimensional concentration fields of the molecular species targeted. Novel advancements in this study include kHz-rate hydroxyl radical (OH) PLIF of combustion phenomena within a supersonic wind tunnel cavity flameholder, the development and demonstration of a 50-kHz OH PLIF system using a small-scale turbulent flame, the development and demonstration of 10-kHz PLIF of the nitric oxide (NO) molecule, and the development and demonstration of a novel strategy for PLIF of the methylidyne (CH) radical at 10 kHz. The methods and diagnostics presented here are on the forefront of the field, extending the limits of the current capabilities to greater imaging rates and expanding the pool of molecular species that can be imaged at high rates. The diagnostics methods are demonstrated in a range of laboratory combustors and propulsion systems. These include (1) an extensive study of a direct microwave plasma coupled flames developed for use in supersonic combustion systems, (2) high enthalpy supersonic combustors, and (3) high shear turbulent combustors. Laser diagnostics are used to examine direct-coupled, plasma ignited and sustained flames, for multiple flame types and nozzle geometries. OH radical number densities are quantified using PLIF and temperature measured by Rayleigh scattering thermometry. High-repetition-rate laser diagnostic methods are implemented to simultaneously record OH PLIF and chemiluminescence within the plasma-enhanced flame, allowing for temporally resolved observation of OH radicals in the plane of the thin laser sheet as well as volume-integrated excited state emission. High-speed OH PLIF is also applied to a Mach 2 combustor to characterize the behavior of the flameholding cavity. The effects of cavity fueling rate are explored and discussed. High-shear turbulent combustors produce convoluted reaction zones, and approach the boundaries between theoretical combustion regimes. Visualization of CH radicals is an excellent way to probe the nature of such flows, and validate theory and computational models. Heretofore, CH PLIF framing rates have been constrained because the strategies have required very high laser pulse energies. In this work a new approach is presented, using the C-X (0,0) transition, which produces excellent… Advisors/Committee Members: Lee, Tonghun (advisor), Lee, Tonghun (Committee Chair), Glumac, Nick G (committee member), Elliot, Gregory S (committee member), Nam, SungWoo (committee member).

Subjects/Keywords: Combustion; Laser Diagnostics

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APA (6^th Edition):

Hammack, S. D. (2015). Development of high-speed laser diagnostics for the study of advanced propulsion systems. (Doctoral Dissertation). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/89121

Chicago Manual of Style (16^th Edition):

Hammack, Stephen Daniel. “Development of high-speed laser diagnostics for the study of advanced propulsion systems.” 2015. Doctoral Dissertation, University of Illinois – Urbana-Champaign. Accessed January 17, 2021. http://hdl.handle.net/2142/89121.

MLA Handbook (7^th Edition):

Hammack, Stephen Daniel. “Development of high-speed laser diagnostics for the study of advanced propulsion systems.” 2015. Web. 17 Jan 2021.

Vancouver:

Hammack SD. Development of high-speed laser diagnostics for the study of advanced propulsion systems. [Internet] [Doctoral dissertation]. University of Illinois – Urbana-Champaign; 2015. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/2142/89121.

Council of Science Editors:

Hammack SD. Development of high-speed laser diagnostics for the study of advanced propulsion systems. [Doctoral Dissertation]. University of Illinois – Urbana-Champaign; 2015. Available from: http://hdl.handle.net/2142/89121

Mississippi State University

7. Banghart, Marc. Bayesian network analysis for diagnostics and prognostics of engineering systems.

Degree: PhD, Industrial and Systems Engineering, 2017, Mississippi State University

URL: http://sun.library.msstate.edu/ETD-db/theses/available/etd-04202017-144204/ ;

► Bayesian networks have been applied to many different domains to perform prognostics, reduce risk and ultimately improve decision making. However, these methods have not… (more)

Subjects/Keywords: risk; prognostics; diagnostics; network; bayesian

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APA (6^th Edition):

Banghart, M. (2017). Bayesian network analysis for diagnostics and prognostics of engineering systems. (Doctoral Dissertation). Mississippi State University. Retrieved from http://sun.library.msstate.edu/ETD-db/theses/available/etd-04202017-144204/ ;

Chicago Manual of Style (16^th Edition):

Banghart, Marc. “Bayesian network analysis for diagnostics and prognostics of engineering systems.” 2017. Doctoral Dissertation, Mississippi State University. Accessed January 17, 2021. http://sun.library.msstate.edu/ETD-db/theses/available/etd-04202017-144204/ ;.

MLA Handbook (7^th Edition):

Banghart, Marc. “Bayesian network analysis for diagnostics and prognostics of engineering systems.” 2017. Web. 17 Jan 2021.

Vancouver:

Banghart M. Bayesian network analysis for diagnostics and prognostics of engineering systems. [Internet] [Doctoral dissertation]. Mississippi State University; 2017. [cited 2021 Jan 17]. Available from: http://sun.library.msstate.edu/ETD-db/theses/available/etd-04202017-144204/ ;.

Council of Science Editors:

Banghart M. Bayesian network analysis for diagnostics and prognostics of engineering systems. [Doctoral Dissertation]. Mississippi State University; 2017. Available from: http://sun.library.msstate.edu/ETD-db/theses/available/etd-04202017-144204/ ;

University of Alberta

8. Chavali Venkata Subramanya, Ravi Shankar. Desiccated and Preserved Polyacrylamide based Nucleic Acid Diagnostic Systems.

Degree: MS, Medical Sciences- Laboratory Medicine and Pathology, 2013, University of Alberta

URL: https://era.library.ualberta.ca/files/2b88qc72t

► The In-gel polymerase chain reaction (PCR) technology developed by our group at the University of Alberta makes use of PCR reagents entrapped within nano-liter polyacrylamide… (more)

Subjects/Keywords: Desiccation; Diagnostics; Nucleic Acid

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APA (6^th Edition):

Chavali Venkata Subramanya, R. S. (2013). Desiccated and Preserved Polyacrylamide based Nucleic Acid Diagnostic Systems. (Masters Thesis). University of Alberta. Retrieved from https://era.library.ualberta.ca/files/2b88qc72t

Chicago Manual of Style (16^th Edition):

Chavali Venkata Subramanya, Ravi Shankar. “Desiccated and Preserved Polyacrylamide based Nucleic Acid Diagnostic Systems.” 2013. Masters Thesis, University of Alberta. Accessed January 17, 2021. https://era.library.ualberta.ca/files/2b88qc72t.

MLA Handbook (7^th Edition):

Chavali Venkata Subramanya, Ravi Shankar. “Desiccated and Preserved Polyacrylamide based Nucleic Acid Diagnostic Systems.” 2013. Web. 17 Jan 2021.

Vancouver:

Chavali Venkata Subramanya RS. Desiccated and Preserved Polyacrylamide based Nucleic Acid Diagnostic Systems. [Internet] [Masters thesis]. University of Alberta; 2013. [cited 2021 Jan 17]. Available from: https://era.library.ualberta.ca/files/2b88qc72t.

Council of Science Editors:

Chavali Venkata Subramanya RS. Desiccated and Preserved Polyacrylamide based Nucleic Acid Diagnostic Systems. [Masters Thesis]. University of Alberta; 2013. Available from: https://era.library.ualberta.ca/files/2b88qc72t

University of Alberta

9. Iwashkiw, Jeremy, A. Identification and Exploitation of Oligosaccharyltransferase Dependent Bacterial Glycosylation Systems.

Degree: PhD, Department of Biological Sciences, 2014, University of Alberta

URL: https://era.library.ualberta.ca/files/cxs55mc13r

► Protein glycosylation, the covalent attachment of carbohydrates to amino acids, was once thought to be a unique attribute of Eukaryotes and select bacteria. However, both… (more)

▼ Protein glycosylation, the covalent attachment of carbohydrates to amino acids, was once thought to be a unique attribute of Eukaryotes and select bacteria. However, both N- (attached to asparagine) and O- (attached to serine or threonine) glycosylation systems have been identified in an ever increasing number of bacteria, including various important human pathogens. Two distinct classes of glycosylation are categorized based on the presence of an oligosaccharyltransferase (OTase). For OTase-independent glycosylation, individual glycosyltransferases (GTs) transfer individual monosaccharides to proteins cytoplasmically. The other class has a more complex pathway, where individual GTs transfer monosaccharides sequentially onto a lipid carrier on the cytoplasmic face of the inner membrane, and when completed, translocated to the periplasmic face, where the OTase transfers the glycan en bloc to acceptor proteins. By exploiting the exponentially increasing number of sequenced bacterial genomes available, in silico analysis has revealed several potential OTase-dependent glycosylation systems. A homologue of Neisseria OTase (PglL) was identified in the emerging Gram negative pathogen Acinetobacter baumannii. This bacterium has been isolated from healthcare facilities for over 40 years, but was not dangerous because it was easily controllable with antibiotics. In the last decade, numerous A. baumannii isolates have developed extreme resistance to antibiotics, desiccation, and disinfectants, leading its classification as a “superbug” and one of the greatest threats to the modern healthcare system. In this thesis, a combination of genetics, molecular and cell biology, mass spectroscopy, and virulence model systems identify and characterize the general O-glycosylation system in A. baumannii. Analysis of the glycoproteome of A. baumannii revealed seven different glycoproteins modified with a pentasaccharide with a unique iii terminal subunit dependent on the OTase PglLAb. Several of these glycoproteins were recombinantly expressed and further analyzed by Western blot and mass spectroscopy. The glycosylation system of A. baumannii can be functionally reconstituted in E. coli, and PglLAb was able to transfer mono-, oligo, and polysaccharides with different structures, with relaxed glycan specificity. Bacteria require protein glycosylation for a variety of functions, including motility and pathogenesis. A. baumannii does not require O-glycosylation for swarming motility, but is essential for biofilms. The glycosylation deficient strain was non pathogenic towards Dictyostellium discoideum (macrophage model), Galleria mellonella (innate immunity response model), and was unable to compete with the wild type in colonizing and killing mice. Additionally, O-glycosylation appears to be important in infecting and killing human alveolar epithelial cells. A. baumannii was observed to cause Eukaryotic cell rounding in a glycosylation dependent manner, but did not cross link actin in vivo. It appears that O-glycosylation is highly conserved in…

Subjects/Keywords: Brucella; Glycobiology; Acinetobacter; Microbiology; Diagnostics

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APA (6^th Edition):

Iwashkiw, Jeremy, A. (2014). Identification and Exploitation of Oligosaccharyltransferase Dependent Bacterial Glycosylation Systems. (Doctoral Dissertation). University of Alberta. Retrieved from https://era.library.ualberta.ca/files/cxs55mc13r

Chicago Manual of Style (16^th Edition):

Iwashkiw, Jeremy, A. “Identification and Exploitation of Oligosaccharyltransferase Dependent Bacterial Glycosylation Systems.” 2014. Doctoral Dissertation, University of Alberta. Accessed January 17, 2021. https://era.library.ualberta.ca/files/cxs55mc13r.

MLA Handbook (7^th Edition):

Iwashkiw, Jeremy, A. “Identification and Exploitation of Oligosaccharyltransferase Dependent Bacterial Glycosylation Systems.” 2014. Web. 17 Jan 2021.

Vancouver:

Iwashkiw, Jeremy A. Identification and Exploitation of Oligosaccharyltransferase Dependent Bacterial Glycosylation Systems. [Internet] [Doctoral dissertation]. University of Alberta; 2014. [cited 2021 Jan 17]. Available from: https://era.library.ualberta.ca/files/cxs55mc13r.

Council of Science Editors:

Iwashkiw, Jeremy A. Identification and Exploitation of Oligosaccharyltransferase Dependent Bacterial Glycosylation Systems. [Doctoral Dissertation]. University of Alberta; 2014. Available from: https://era.library.ualberta.ca/files/cxs55mc13r

Cornell University

10. Ruiz, Roanna. Dna Materials For Diagnostic Applications.

Degree: PhD, Biomedical Engineering, 2015, Cornell University

URL: http://hdl.handle.net/1813/41152

► The extraordinary controllability of DNA nanostructures provides great potential for nanotechnology and biotechnology, with diverse applications including drug delivery, sensing, and materials synthesis. However, DNA-based… (more)

Subjects/Keywords: DNA Nanotechnology; Pathogen Diagnostics; Microfluidics

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APA (6^th Edition):

Ruiz, R. (2015). Dna Materials For Diagnostic Applications. (Doctoral Dissertation). Cornell University. Retrieved from http://hdl.handle.net/1813/41152

Chicago Manual of Style (16^th Edition):

Ruiz, Roanna. “Dna Materials For Diagnostic Applications.” 2015. Doctoral Dissertation, Cornell University. Accessed January 17, 2021. http://hdl.handle.net/1813/41152.

MLA Handbook (7^th Edition):

Ruiz, Roanna. “Dna Materials For Diagnostic Applications.” 2015. Web. 17 Jan 2021.

Vancouver:

Ruiz R. Dna Materials For Diagnostic Applications. [Internet] [Doctoral dissertation]. Cornell University; 2015. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1813/41152.

Council of Science Editors:

Ruiz R. Dna Materials For Diagnostic Applications. [Doctoral Dissertation]. Cornell University; 2015. Available from: http://hdl.handle.net/1813/41152

11. Tajik, Daniel. Advances in Quantitative Microwave Holography.

Degree: MASc, 2017, McMaster University

URL: http://hdl.handle.net/11375/22259

►

Microwave imaging has been used to observe optically obscured targets for over 40 years. Recently, there has been a push towards developing a microwave imaging… (more)

Subjects/Keywords: microwave imaging; electromagnetics; algorithms; diagnostics

14 more images…

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APA (6^th Edition):

Tajik, D. (2017). Advances in Quantitative Microwave Holography. (Masters Thesis). McMaster University. Retrieved from http://hdl.handle.net/11375/22259

Chicago Manual of Style (16^th Edition):

Tajik, Daniel. “Advances in Quantitative Microwave Holography.” 2017. Masters Thesis, McMaster University. Accessed January 17, 2021. http://hdl.handle.net/11375/22259.

MLA Handbook (7^th Edition):

Tajik, Daniel. “Advances in Quantitative Microwave Holography.” 2017. Web. 17 Jan 2021.

Vancouver:

Tajik D. Advances in Quantitative Microwave Holography. [Internet] [Masters thesis]. McMaster University; 2017. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/11375/22259.

Council of Science Editors:

Tajik D. Advances in Quantitative Microwave Holography. [Masters Thesis]. McMaster University; 2017. Available from: http://hdl.handle.net/11375/22259

Texas A&M University

12. Hanna, Sherif Fayez. Electronic resonance enhanced coherent anti-Stokes Raman scattering technique for detection of combustion species and biological molecules.

Degree: PhD, Mechanical Engineering, 2006, Texas A&M University

URL: http://hdl.handle.net/1969.1/4379

► The application of electronic-resonance enhanced (ERE) coherent anti-Stokes Raman scattering (CARS) for the detection of nitric oxide (NO) and acetylene (C2H2) is experimentally demonstrated and… (more)

▼ The application of electronic-resonance enhanced (ERE) coherent anti-Stokes Raman scattering (CARS) for the detection of nitric oxide (NO) and acetylene (C2H2) is experimentally demonstrated and the effects of various parameters on the ERE CARS signal investigated. In addition, the detection of dipicolinic acid (DPA) using Ã¢ÂÂnormalÃ¢ÂÂ CARS is demonstrated. For NO detection, the frequency difference between a visible Raman pump beam and Stokes beam is tuned to a vibrational Q-branch Raman resonance of the No molecule to create a Raman polarization in the medium. The second pump beam is tuned into resonance with the rotational transitions in the (1,0) band of the A2ÃÂ£+-X2ÃÂ electronic transition at 236 nm, and the CARS signal is thus resonant with transitions in the (0,0) band. A NO gas cell was used for the experiment to detect NO at various pressure levels. A significant resonant enhancement of the NO CARS signal was observed and good agreement between calculated and experimental data was obtained. For C2H2 detection, ERE CARS experiments were performed in a roomtemperature gas cell using mixtures of 5000 ppm C2H2 in N2. Visible pump and Stokes beams were used, with the frequency difference between the pump and Stokes tuned to the 1974 cm-1 ÃÂ2 Raman transition of C2H2. An ultraviolet probe beam with the wavelengths ranging from 232 nm to 242 nm is scattered from the induced Raman polarization to generate the ERE CARS signal. The effects of probe wavelength and pressure on signal generation are discussed. CARS was used to detect the 998 cm-1 vibrational Raman transition from a sample of polycrystalline DPA. The transition is the breathing ring vibration in the pyridine ring structure in the DPA molecule. The DPA 998 cm-1 transition is detected with excellent signal-to-noise ratio and the full-width-at-half-maximum is very narrow, approximately 4 cm-1. Advisors/Committee Members: Caton, Jerald A. (advisor), Lucht, Robert P. (advisor), Annamalai, Kalyan (committee member), Welch, George R. (committee member).

Subjects/Keywords: laser; diagnostics

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APA (6^th Edition):

Hanna, S. F. (2006). Electronic resonance enhanced coherent anti-Stokes Raman scattering technique for detection of combustion species and biological molecules. (Doctoral Dissertation). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/4379

Chicago Manual of Style (16^th Edition):

Hanna, Sherif Fayez. “Electronic resonance enhanced coherent anti-Stokes Raman scattering technique for detection of combustion species and biological molecules.” 2006. Doctoral Dissertation, Texas A&M University. Accessed January 17, 2021. http://hdl.handle.net/1969.1/4379.

MLA Handbook (7^th Edition):

Hanna, Sherif Fayez. “Electronic resonance enhanced coherent anti-Stokes Raman scattering technique for detection of combustion species and biological molecules.” 2006. Web. 17 Jan 2021.

Vancouver:

Hanna SF. Electronic resonance enhanced coherent anti-Stokes Raman scattering technique for detection of combustion species and biological molecules. [Internet] [Doctoral dissertation]. Texas A&M University; 2006. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1969.1/4379.

Council of Science Editors:

Hanna SF. Electronic resonance enhanced coherent anti-Stokes Raman scattering technique for detection of combustion species and biological molecules. [Doctoral Dissertation]. Texas A&M University; 2006. Available from: http://hdl.handle.net/1969.1/4379

13. Saxena, Rakesh Kumar. Studies in sonic diagnostics of plasma; -.

Degree: Physics, 1976, Pt. Ravishankar Shukla University

URL: http://shodhganga.inflibnet.ac.in/handle/10603/43175

None

Bibliography given

Advisors/Committee Members: Saxena, A P.

Subjects/Keywords: diagnostics; Plasma

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APA (6^th Edition):

Saxena, R. K. (1976). Studies in sonic diagnostics of plasma; -. (Thesis). Pt. Ravishankar Shukla University. Retrieved from http://shodhganga.inflibnet.ac.in/handle/10603/43175

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Saxena, Rakesh Kumar. “Studies in sonic diagnostics of plasma; -.” 1976. Thesis, Pt. Ravishankar Shukla University. Accessed January 17, 2021. http://shodhganga.inflibnet.ac.in/handle/10603/43175.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Saxena, Rakesh Kumar. “Studies in sonic diagnostics of plasma; -.” 1976. Web. 17 Jan 2021.

Vancouver:

Saxena RK. Studies in sonic diagnostics of plasma; -. [Internet] [Thesis]. Pt. Ravishankar Shukla University; 1976. [cited 2021 Jan 17]. Available from: http://shodhganga.inflibnet.ac.in/handle/10603/43175.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Saxena RK. Studies in sonic diagnostics of plasma; -. [Thesis]. Pt. Ravishankar Shukla University; 1976. Available from: http://shodhganga.inflibnet.ac.in/handle/10603/43175

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Toronto

14. Vasilyeva, Elizaveta. Detection of the BCR-ABL Leukemia Gene Fusion using Chip-based Electrochemical Assay.

Degree: 2010, University of Toronto

URL: http://hdl.handle.net/1807/30135

►

Ability to diagnose cancer before it progresses into advanced stages is highly desirable for the best treatment outcome. A sensitive test to analyze complex samples… (more)

Subjects/Keywords: biosensor; CML; diagnostics; 0487

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APA (6^th Edition):

Vasilyeva, E. (2010). Detection of the BCR-ABL Leukemia Gene Fusion using Chip-based Electrochemical Assay. (Masters Thesis). University of Toronto. Retrieved from http://hdl.handle.net/1807/30135

Chicago Manual of Style (16^th Edition):

Vasilyeva, Elizaveta. “Detection of the BCR-ABL Leukemia Gene Fusion using Chip-based Electrochemical Assay.” 2010. Masters Thesis, University of Toronto. Accessed January 17, 2021. http://hdl.handle.net/1807/30135.

MLA Handbook (7^th Edition):

Vasilyeva, Elizaveta. “Detection of the BCR-ABL Leukemia Gene Fusion using Chip-based Electrochemical Assay.” 2010. Web. 17 Jan 2021.

Vancouver:

Vasilyeva E. Detection of the BCR-ABL Leukemia Gene Fusion using Chip-based Electrochemical Assay. [Internet] [Masters thesis]. University of Toronto; 2010. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1807/30135.

Council of Science Editors:

Vasilyeva E. Detection of the BCR-ABL Leukemia Gene Fusion using Chip-based Electrochemical Assay. [Masters Thesis]. University of Toronto; 2010. Available from: http://hdl.handle.net/1807/30135

University of Toronto

15. Homme, Paige. Whole-cell regenerating 'microbead' to capture disease antibodies using the yeast species, Pichia pastoris.

Degree: 2017, University of Toronto

URL: http://hdl.handle.net/1807/89425

►

Guiding appropriate medical treatment and population surveillance are examples of the crucial functions of diagnostics in health care [1]. Antibody based assays are routinely employed,… (more)

Subjects/Keywords: Diagnostics; Synthetic biology; Yeast; 0202

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APA (6^th Edition):

Homme, P. (2017). Whole-cell regenerating 'microbead' to capture disease antibodies using the yeast species, Pichia pastoris. (Masters Thesis). University of Toronto. Retrieved from http://hdl.handle.net/1807/89425

Chicago Manual of Style (16^th Edition):

Homme, Paige. “Whole-cell regenerating 'microbead' to capture disease antibodies using the yeast species, Pichia pastoris.” 2017. Masters Thesis, University of Toronto. Accessed January 17, 2021. http://hdl.handle.net/1807/89425.

MLA Handbook (7^th Edition):

Homme, Paige. “Whole-cell regenerating 'microbead' to capture disease antibodies using the yeast species, Pichia pastoris.” 2017. Web. 17 Jan 2021.

Vancouver:

Homme P. Whole-cell regenerating 'microbead' to capture disease antibodies using the yeast species, Pichia pastoris. [Internet] [Masters thesis]. University of Toronto; 2017. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1807/89425.

Council of Science Editors:

Homme P. Whole-cell regenerating 'microbead' to capture disease antibodies using the yeast species, Pichia pastoris. [Masters Thesis]. University of Toronto; 2017. Available from: http://hdl.handle.net/1807/89425

University of Toronto

16. Homme, Paige. Whole-cell regenerating 'microbead' to capture disease antibodies using the yeast species, Pichia pastoris.

Degree: 2017, University of Toronto

URL: http://hdl.handle.net/1807/96003

►

Guiding appropriate medical treatment and population surveillance are examples of the crucial functions of diagnostics in health care [1]. Antibody based assays are routinely employed,… (more)

Subjects/Keywords: Diagnostics; Synthetic biology; Yeast; 0202

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APA (6^th Edition):

Homme, P. (2017). Whole-cell regenerating 'microbead' to capture disease antibodies using the yeast species, Pichia pastoris. (Masters Thesis). University of Toronto. Retrieved from http://hdl.handle.net/1807/96003

Chicago Manual of Style (16^th Edition):

Homme, Paige. “Whole-cell regenerating 'microbead' to capture disease antibodies using the yeast species, Pichia pastoris.” 2017. Masters Thesis, University of Toronto. Accessed January 17, 2021. http://hdl.handle.net/1807/96003.

MLA Handbook (7^th Edition):

Homme, Paige. “Whole-cell regenerating 'microbead' to capture disease antibodies using the yeast species, Pichia pastoris.” 2017. Web. 17 Jan 2021.

Vancouver:

Homme P. Whole-cell regenerating 'microbead' to capture disease antibodies using the yeast species, Pichia pastoris. [Internet] [Masters thesis]. University of Toronto; 2017. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1807/96003.

Council of Science Editors:

Homme P. Whole-cell regenerating 'microbead' to capture disease antibodies using the yeast species, Pichia pastoris. [Masters Thesis]. University of Toronto; 2017. Available from: http://hdl.handle.net/1807/96003

Harvard University

17. Ter-Ovanesyan, Dmitry. Investigation of RNA in Extracellular Vesicles.

Degree: PhD, 2019, Harvard University

URL: http://nrs.harvard.edu/urn-3:HUL.InstRepos:41121318

►

Extracellular vesicles (EVs) are small membrane packages that are released by all cells. About a decade ago, it was found that EVs contain RNA, and… (more)

Subjects/Keywords: extracellular vesicles; vesicles; RNA; diagnostics

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APA (6^th Edition):

Ter-Ovanesyan, D. (2019). Investigation of RNA in Extracellular Vesicles. (Doctoral Dissertation). Harvard University. Retrieved from http://nrs.harvard.edu/urn-3:HUL.InstRepos:41121318

Chicago Manual of Style (16^th Edition):

Ter-Ovanesyan, Dmitry. “Investigation of RNA in Extracellular Vesicles.” 2019. Doctoral Dissertation, Harvard University. Accessed January 17, 2021. http://nrs.harvard.edu/urn-3:HUL.InstRepos:41121318.

MLA Handbook (7^th Edition):

Ter-Ovanesyan, Dmitry. “Investigation of RNA in Extracellular Vesicles.” 2019. Web. 17 Jan 2021.

Vancouver:

Ter-Ovanesyan D. Investigation of RNA in Extracellular Vesicles. [Internet] [Doctoral dissertation]. Harvard University; 2019. [cited 2021 Jan 17]. Available from: http://nrs.harvard.edu/urn-3:HUL.InstRepos:41121318.

Council of Science Editors:

Ter-Ovanesyan D. Investigation of RNA in Extracellular Vesicles. [Doctoral Dissertation]. Harvard University; 2019. Available from: http://nrs.harvard.edu/urn-3:HUL.InstRepos:41121318

University of Oxford

18. Harrison, Hannah. Design of single-shot longitudinal bunch profile monitor based on analysis of coherent Smith-Purcell radiation.

Degree: PhD, 2018, University of Oxford

URL: http://ora.ox.ac.uk/objects/uuid:a3bc1f29-0ade-4f7d-ae9c-b40f1e0371f3 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.780540

► The spectral analysis of coherent Smith-Purcell radiation (cSPr) is a promising new longitudinal diagnostic technique. This thesis presents a conceptual design for a single-shot, non-destructive,… (more)

Subjects/Keywords: Longitudinal Beam Diagnostics; Accelerator Physics

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APA (6^th Edition):

Harrison, H. (2018). Design of single-shot longitudinal bunch profile monitor based on analysis of coherent Smith-Purcell radiation. (Doctoral Dissertation). University of Oxford. Retrieved from http://ora.ox.ac.uk/objects/uuid:a3bc1f29-0ade-4f7d-ae9c-b40f1e0371f3 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.780540

Chicago Manual of Style (16^th Edition):

Harrison, Hannah. “Design of single-shot longitudinal bunch profile monitor based on analysis of coherent Smith-Purcell radiation.” 2018. Doctoral Dissertation, University of Oxford. Accessed January 17, 2021. http://ora.ox.ac.uk/objects/uuid:a3bc1f29-0ade-4f7d-ae9c-b40f1e0371f3 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.780540.

MLA Handbook (7^th Edition):

Harrison, Hannah. “Design of single-shot longitudinal bunch profile monitor based on analysis of coherent Smith-Purcell radiation.” 2018. Web. 17 Jan 2021.

Vancouver:

Harrison H. Design of single-shot longitudinal bunch profile monitor based on analysis of coherent Smith-Purcell radiation. [Internet] [Doctoral dissertation]. University of Oxford; 2018. [cited 2021 Jan 17]. Available from: http://ora.ox.ac.uk/objects/uuid:a3bc1f29-0ade-4f7d-ae9c-b40f1e0371f3 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.780540.

Council of Science Editors:

Harrison H. Design of single-shot longitudinal bunch profile monitor based on analysis of coherent Smith-Purcell radiation. [Doctoral Dissertation]. University of Oxford; 2018. Available from: http://ora.ox.ac.uk/objects/uuid:a3bc1f29-0ade-4f7d-ae9c-b40f1e0371f3 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.780540

University of Dundee

19. Stewart, Neil Andrew. Novel multifunctional laser diagnostics.

Degree: PhD, 2013, University of Dundee

URL: https://discovery.dundee.ac.uk/en/studentTheses/ddee58ac-0fda-41ca-9485-c74920cf3852 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.613572

► The research presented in this thesis set out to contribute to knowledge seeking to advance the state-of-the-art in laser based, multi-functional, non-invasive diagnostic systems. The… (more)

Subjects/Keywords: 610; biophotonics; diagnostics; spectroscopy

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APA (6^th Edition):

Stewart, N. A. (2013). Novel multifunctional laser diagnostics. (Doctoral Dissertation). University of Dundee. Retrieved from https://discovery.dundee.ac.uk/en/studentTheses/ddee58ac-0fda-41ca-9485-c74920cf3852 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.613572

Chicago Manual of Style (16^th Edition):

Stewart, Neil Andrew. “Novel multifunctional laser diagnostics.” 2013. Doctoral Dissertation, University of Dundee. Accessed January 17, 2021. https://discovery.dundee.ac.uk/en/studentTheses/ddee58ac-0fda-41ca-9485-c74920cf3852 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.613572.

MLA Handbook (7^th Edition):

Stewart, Neil Andrew. “Novel multifunctional laser diagnostics.” 2013. Web. 17 Jan 2021.

Vancouver:

Stewart NA. Novel multifunctional laser diagnostics. [Internet] [Doctoral dissertation]. University of Dundee; 2013. [cited 2021 Jan 17]. Available from: https://discovery.dundee.ac.uk/en/studentTheses/ddee58ac-0fda-41ca-9485-c74920cf3852 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.613572.

Council of Science Editors:

Stewart NA. Novel multifunctional laser diagnostics. [Doctoral Dissertation]. University of Dundee; 2013. Available from: https://discovery.dundee.ac.uk/en/studentTheses/ddee58ac-0fda-41ca-9485-c74920cf3852 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.613572

University of Debrecen

20. Singh, Kavan. Advanced diagnostic methods in periodontology .

Degree: DE – Fogorvostudományi Kar, University of Debrecen

URL: http://hdl.handle.net/2437/241015

► Advanced diagnostic methods in periodontology focuses on the techniques used to measure the extent of periodontal diseases. The methods include a physical examination, microbiology and… (more)

Subjects/Keywords: Diagnostics; Periodontology

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APA (6^th Edition):

Singh, K. (n.d.). Advanced diagnostic methods in periodontology . (Thesis). University of Debrecen. Retrieved from http://hdl.handle.net/2437/241015

Note: this citation may be lacking information needed for this citation format:
No year of publication.
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Singh, Kavan. “Advanced diagnostic methods in periodontology .” Thesis, University of Debrecen. Accessed January 17, 2021. http://hdl.handle.net/2437/241015.

Note: this citation may be lacking information needed for this citation format:
No year of publication.
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Singh, Kavan. “Advanced diagnostic methods in periodontology .” Web. 17 Jan 2021.

Note: this citation may be lacking information needed for this citation format:
No year of publication.

Vancouver:

Singh K. Advanced diagnostic methods in periodontology . [Internet] [Thesis]. University of Debrecen; [cited 2021 Jan 17]. Available from: http://hdl.handle.net/2437/241015.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
No year of publication.

Council of Science Editors:

Singh K. Advanced diagnostic methods in periodontology . [Thesis]. University of Debrecen; Available from: http://hdl.handle.net/2437/241015

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
No year of publication.

Rice University

21. Wu, Ruojia. Simple, Multiplexed, and Ultraspecific Nucleic Acid-based Diagnostic Technologies.

Degree: PhD, Engineering, 2017, Rice University

URL: http://hdl.handle.net/1911/105491

► The economical and high-throughput detection and quantitation of disease-relevant nucleic acid sequences is a key goal in the road to widespread adoption of precision medicine,… (more)

Subjects/Keywords: Molecular diagnostics; nucleic acids

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APA (6^th Edition):

Wu, R. (2017). Simple, Multiplexed, and Ultraspecific Nucleic Acid-based Diagnostic Technologies. (Doctoral Dissertation). Rice University. Retrieved from http://hdl.handle.net/1911/105491

Chicago Manual of Style (16^th Edition):

Wu, Ruojia. “Simple, Multiplexed, and Ultraspecific Nucleic Acid-based Diagnostic Technologies.” 2017. Doctoral Dissertation, Rice University. Accessed January 17, 2021. http://hdl.handle.net/1911/105491.

MLA Handbook (7^th Edition):

Wu, Ruojia. “Simple, Multiplexed, and Ultraspecific Nucleic Acid-based Diagnostic Technologies.” 2017. Web. 17 Jan 2021.

Vancouver:

Wu R. Simple, Multiplexed, and Ultraspecific Nucleic Acid-based Diagnostic Technologies. [Internet] [Doctoral dissertation]. Rice University; 2017. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1911/105491.

Council of Science Editors:

Wu R. Simple, Multiplexed, and Ultraspecific Nucleic Acid-based Diagnostic Technologies. [Doctoral Dissertation]. Rice University; 2017. Available from: http://hdl.handle.net/1911/105491

Rice University

22. Yan, Yan. Rationally Designed Hybridization Systems for Nucleic Acid Diagnostics and Sequence Analysis.

Degree: PhD, Natural Sciences, 2019, Rice University

URL: http://hdl.handle.net/1911/105993

► Detection of changes in a nucleic acid sequence is crucial in genomics research and precision medicine. With the advances of new generation’s of technology platforms,… (more)

▼ Detection of changes in a nucleic acid sequence is crucial in genomics research and precision medicine. With the advances of new generation’s of technology platforms, researchers have been able to study the fundamental causes of human diseases in DNA or RNA level, leading to optimal targeted treatment, real-time monitoring of disease progression, and ultimately early diagnosis and intervention before symptoms occur. Although people have been developing nucleic acid based assays for decades, the common methodology that people use in the design process of nucleic acid based assays are trial and error adjustment of probe or primer sequences and empirical optimization of buffer conditions. These methods offer quantitatively improvements of nucleic acid reaction behaviors (yield and specificity) to a certain degree, but are hard to achieve qualitative breakthroughs. During my PhD, my main focus is how to use the “rational design” concept in nucleic acid technology development. Our lab has an extensive background in nucleic acid hybridization biophysics, which facilitates reliable and generalizable in silico assay and device design with little empirical optimization. As demonstration, 4 technologies have been developed with 4 manuscripts to provide potential solutions for 4 different application fields: 1) DNA signaling and computing device [1] Yan Helen Yan, David Yu Zhang and Lucia R. Wu. “Encoding multiple digital DNA signals in a single analog channel” manuscript in preparation. 2) Hybridization probe [2] Juexiao Sherry Wang*, Yan Helen Yan* and David Yu Zhang. “Modular probes for enriching and detecting complex nucleic acid sequences.” Nature chemistry 9.12 (2017): 1222. *Equal contribution 3) Next generation sequencing [3] Yan Helen Yan and David Yu Zhang. “Symbolic Sequencing of DNA and RNA Via Sequence Encoding.” manuscript in preparation. 4) Quantitative PCR [4] Ping Song, Sherry X. Chen, Yan Helen Yan and David Yu Zhang. “Detecting and Identifying Low Fraction Conspecific DNA” in submission to Nature Methods. These works are not meant to be final, optimized designs for assays and devices, but rather demonstrations of the wide range of problems that can be solved with nucleic acid rational design. Advisors/Committee Members: Zhang, David Yu (advisor).

Subjects/Keywords: DNA biophysics; molecular diagnostics; probes

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APA (6^th Edition):

Yan, Y. (2019). Rationally Designed Hybridization Systems for Nucleic Acid Diagnostics and Sequence Analysis. (Doctoral Dissertation). Rice University. Retrieved from http://hdl.handle.net/1911/105993

Chicago Manual of Style (16^th Edition):

Yan, Yan. “Rationally Designed Hybridization Systems for Nucleic Acid Diagnostics and Sequence Analysis.” 2019. Doctoral Dissertation, Rice University. Accessed January 17, 2021. http://hdl.handle.net/1911/105993.

MLA Handbook (7^th Edition):

Yan, Yan. “Rationally Designed Hybridization Systems for Nucleic Acid Diagnostics and Sequence Analysis.” 2019. Web. 17 Jan 2021.

Vancouver:

Yan Y. Rationally Designed Hybridization Systems for Nucleic Acid Diagnostics and Sequence Analysis. [Internet] [Doctoral dissertation]. Rice University; 2019. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1911/105993.

Council of Science Editors:

Yan Y. Rationally Designed Hybridization Systems for Nucleic Acid Diagnostics and Sequence Analysis. [Doctoral Dissertation]. Rice University; 2019. Available from: http://hdl.handle.net/1911/105993

Victoria University of Wellington

23. Bryson, Richard Vernon. Infrastructure asset diagnostics: Enabling smarter asset management decisions within the electricity distribution industry.

Degree: 2017, Victoria University of Wellington

URL: http://hdl.handle.net/10063/6390

► This thesis examines the opportunities for better asset management within the electricity distribution industry. The project partner, a supplier of distribution products, observed their customers… (more)

▼ This thesis examines the opportunities for better asset management within the electricity distribution industry. The project partner, a supplier of distribution products, observed their customers are often purchasing incorrect equipment for maintenance operations. This observation led the project partner to believe a lack of accurate asset knowledge exists within these electricity distribution businesses (EDBs). Coupled with the information that much of the installed asset base of these EDBs is approaching end of life, it was proposed to investigate the suspected lack of asset condition and type knowledge with the intention of developing the Infrastructure Asset Diagnostic Tool (IADT). A literature review was conducted to determine the current state of asset diagnostics within the electricity distribution industry. The principles of lean start-up business development have been used to isolate the most needed technology within the New Zealand marketplace through interviews with industry personnel. These interviews helped identify a possible Minimum Viable Product (MVP) for the IADT, and also indicated that providing the IADT as a professional service would be the most appropriate model for the MVP variant. Condition and type knowledge of wooden poles, conductors and line hardware was found to be the most lacking. It was recommended to focus product development on the assessment of these assets. The project partner has contracted two smart tool suppliers for the analysis of poles and conductor clearances. These products were then integrated to enable accurate assessments of wooden poles. An additional product identified as an aside during the interviews, was for a simple pole designing application which could be used in the field. An existing product from one of the smart tool suppliers contracted can fulfil this requirement. Possible benefits from IADT use were calculated for a sample EDB. These calculations indicated accurate condition assessment of wooden poles could lead to a saving of up to $5.4 million per year. This saving would equate to a possible reduction in time for securing pole integrity on this network from 30.8 years to just 5.9 years through more effective use of available funding. This reduction would lead to enhanced network reliability and improved public safety in a much shorter time frame than present, therefore this study recommends implementing the MVP form of the IADT at an initial EDB. Advisors/Committee Members: Long, Nicholas.

Subjects/Keywords: Infrastructure; Asset; Electricity; Diagnostics

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APA (6^th Edition):

Bryson, R. V. (2017). Infrastructure asset diagnostics: Enabling smarter asset management decisions within the electricity distribution industry. (Masters Thesis). Victoria University of Wellington. Retrieved from http://hdl.handle.net/10063/6390

Chicago Manual of Style (16^th Edition):

Bryson, Richard Vernon. “Infrastructure asset diagnostics: Enabling smarter asset management decisions within the electricity distribution industry.” 2017. Masters Thesis, Victoria University of Wellington. Accessed January 17, 2021. http://hdl.handle.net/10063/6390.

MLA Handbook (7^th Edition):

Bryson, Richard Vernon. “Infrastructure asset diagnostics: Enabling smarter asset management decisions within the electricity distribution industry.” 2017. Web. 17 Jan 2021.

Vancouver:

Bryson RV. Infrastructure asset diagnostics: Enabling smarter asset management decisions within the electricity distribution industry. [Internet] [Masters thesis]. Victoria University of Wellington; 2017. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/10063/6390.

Council of Science Editors:

Bryson RV. Infrastructure asset diagnostics: Enabling smarter asset management decisions within the electricity distribution industry. [Masters Thesis]. Victoria University of Wellington; 2017. Available from: http://hdl.handle.net/10063/6390

George Mason University

24. Shafagati, Nazly. Enhanced Detection of Influenza with Nanotrap Particles .

Degree: 2015, George Mason University

URL: http://hdl.handle.net/1920/9820

► The Influenza virus is a leading cause of respiratory disease in the United States each year. The virus normally causes mild to moderate disease, however,… (more)

Subjects/Keywords: Diagnostics; Influenza; Nanotrap particles

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APA (6^th Edition):

Shafagati, N. (2015). Enhanced Detection of Influenza with Nanotrap Particles . (Thesis). George Mason University. Retrieved from http://hdl.handle.net/1920/9820

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Shafagati, Nazly. “Enhanced Detection of Influenza with Nanotrap Particles .” 2015. Thesis, George Mason University. Accessed January 17, 2021. http://hdl.handle.net/1920/9820.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Shafagati, Nazly. “Enhanced Detection of Influenza with Nanotrap Particles .” 2015. Web. 17 Jan 2021.

Vancouver:

Shafagati N. Enhanced Detection of Influenza with Nanotrap Particles . [Internet] [Thesis]. George Mason University; 2015. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1920/9820.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Shafagati N. Enhanced Detection of Influenza with Nanotrap Particles . [Thesis]. George Mason University; 2015. Available from: http://hdl.handle.net/1920/9820

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

25. Retter, Jonathan Eric. Velocity, temperature, and electric field measurements on a plasma-assisted hydrogen diffusion flame.

Degree: PhD, Aerospace Engineering, 2018, University of Illinois – Urbana-Champaign

URL: http://hdl.handle.net/2142/102426

► A plasma-assisted hydrogen diffusion flame, denoted as a coaxial AC DBD burner, was designed and analyzed for comparisons with simulations and to better understand the… (more)

▼ A plasma-assisted hydrogen diffusion flame, denoted as a coaxial AC DBD burner, was designed and analyzed for comparisons with simulations and to better understand the coupling of the plasma and reacting flow. Emission, PLIF, and schlieren imaging of the burner revealed three distinct operating regimes of the flame, from a reference flickering flame with no applied potential, through a regime of wide flames at moderate potentials from 4-7 kV peak, to the fully collapsed or flattened flame at the highest potentials considered in this work at 9 kV peak voltage all at 18 kHz. Particle image velocimetry measurements revealed the formation of a toroidal vortex within the flame, beginning as an internal toroidal vortex in the wide flame regime, and switching to an outer toroidal vortex in the collapsed flame regime, producing a near counter flow flat diffusion flame on the burner surface that is ventilated by this toroidal vortex. Thermal and species measurements of the flame, by means of Rayleigh or Raman scattering techniques, in different regimes demonstrated a change in the fuel mixing structure and location of the reaction zone due to the position and intensity of the plasma-induced toroidal vortex. Finally, optical electric field measurements, from an electric field induced second harmonic generation technique, revealed the spatial-temporal structure of the horizontal and vertical components of the electric field over the top surface of the burner, thus completing the velocity, temperature, and electric field measurements on this plasma assisted burner. These electric field measurements, coupled with PIV measurements, produced new insight into the body force effect of AC DBD discharges. The electric field measurements revealed period-averaged biases in the electric field as a function of position above the burner surface. Mapping the response of positively charged ions to this period biased electric field showed the ions travelled in the same direction as the bulk flow measured with PIV, suggesting the period-averaged momentum transfer of the ions to the neutral molecules integrated over many AC periods is the leading cause of this induced flow velocity. This was true for both quiescent air operation of the DBD, as well as cold flow operation which resulted in a complete reversal of the bulk flow direction. The specific diagnostic tools utilized to examine the fundamental characteristics of the DBD burner are not new techniques, but the application of them to the complex environment of the burner led to additional developments that allowed for the actual measurement of the quantities of interest. For the PIV measurements, the collapsed flame configuration led to issues with the alumina solid particle seeding momentum dominating the flowfield. This led to utilizing flame synthesis of silica to seed the flame, thus having a self-seeding collapsed flame for velocity measurements. Filtered Rayleigh scattering signals were a combination of species and temperature, thus relying on spontaneous Raman measurements to… Advisors/Committee Members: Elliott, Gregory S (advisor), Elliott, Gregory S (Committee Chair), Dutton, J. Craig (committee member), Freund, Jonathan B (committee member), Kearney, Sean P (committee member).

Subjects/Keywords: combustion; plasma; laser diagnostics

10 more images…

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APA (6^th Edition):

Retter, J. E. (2018). Velocity, temperature, and electric field measurements on a plasma-assisted hydrogen diffusion flame. (Doctoral Dissertation). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/102426

Chicago Manual of Style (16^th Edition):

Retter, Jonathan Eric. “Velocity, temperature, and electric field measurements on a plasma-assisted hydrogen diffusion flame.” 2018. Doctoral Dissertation, University of Illinois – Urbana-Champaign. Accessed January 17, 2021. http://hdl.handle.net/2142/102426.

MLA Handbook (7^th Edition):

Retter, Jonathan Eric. “Velocity, temperature, and electric field measurements on a plasma-assisted hydrogen diffusion flame.” 2018. Web. 17 Jan 2021.

Vancouver:

Retter JE. Velocity, temperature, and electric field measurements on a plasma-assisted hydrogen diffusion flame. [Internet] [Doctoral dissertation]. University of Illinois – Urbana-Champaign; 2018. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/2142/102426.

Council of Science Editors:

Retter JE. Velocity, temperature, and electric field measurements on a plasma-assisted hydrogen diffusion flame. [Doctoral Dissertation]. University of Illinois – Urbana-Champaign; 2018. Available from: http://hdl.handle.net/2142/102426

University of Melbourne

26. TEBRUEGGE, MARC. Novel approaches to the immunodiagnosis of childhood tuberculosis.

Degree: 2012, University of Melbourne

URL: http://hdl.handle.net/11343/38055

► Approximately one-third of the global population is infected with Mycobacterium tuberculosis (MTB). Despite a number of advances, tuberculosis (TB) remains one of the diagnostically most… (more)

▼ Approximately one-third of the global population is infected with Mycobacterium tuberculosis (MTB). Despite a number of advances, tuberculosis (TB) remains one of the diagnostically most challenging diseases. For almost a century, the tuberculin skin test (TST) was the only method available to identify latent TB infection (LTBI). However, the TST has variable sensitivity and limited specificity. In 2002, a new generation of immune-based tests, interferon-γ release assays (IGRA), were licensed for clinical use. IGRA rely on the detection of interferon-γ produced by sensitised T cells in response to stimulation with relatively MTB-specific antigens. Since these are absent from all BCG vaccine strains and most non-tuberculous mycobacteria, it is assumed that IGRA have greater specificity than the TST. However, increasing data cast doubt on the performance of IGRA, especially in the paediatric setting. Two constellations are particularly common in children: (a) discordance between TST and IGRA results (ie TST+/IGRA- or-TST-/IGRA+), and (b) indeterminate IGRA results. The underlying basis for discordance remains unknown and it is uncertain which of the test results accurately reflects the true TB infection status. Both indeterminate and discordant IGRA results present a considerable management dilemma in clinical practice. The principle hypothesis of this thesis was that a detailed analysis of mycobacteria-specific cellular immune responses would provide insights into the origins of discordance, and provide important information to enable the development of improved immunoassays for the diagnosis of TB. This thesis begins with a systematic review of the literature on the performance of IGRA in children, highlighting the lack of evidence supporting the hypothesis that prior BCG vaccination and exposure to non-tuberculous mycobacteria are the primary cause of common discordance (TST+/IGRA-). The next chapter describes the development of whole blood assays that enable detailed analyses of mycobacteria-specific immune responses. It also describes the development of a complex multi-colour flow cytometric procedure for simultaneous analysis of major T cell surface markers (CD3, CD4, CD8), T cell memory markers (CD45RA, CCR7) and intracellular cytokines (IFN-γ, IL-2, TNF-α, IL-17), as well as the optimisation of Luminex bead-based cytokine assays used to determine mycobacteria-specific cytokine responses in supernatants. The subsequent chapters describe the results of a clinical study in children at risk of TB infection that used these methods. The data show that individuals with common discordance are a heterogeneous group, comprising both TB-uninfected and TB-infected cases. A number of mycobacteria-specific cytokine responses that have the potential to improve diagnostic assays for TB were identified.…

Subjects/Keywords: tuberculosis; diagnostics; child; immunology

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APA (6^th Edition):

TEBRUEGGE, M. (2012). Novel approaches to the immunodiagnosis of childhood tuberculosis. (Doctoral Dissertation). University of Melbourne. Retrieved from http://hdl.handle.net/11343/38055

Chicago Manual of Style (16^th Edition):

TEBRUEGGE, MARC. “Novel approaches to the immunodiagnosis of childhood tuberculosis.” 2012. Doctoral Dissertation, University of Melbourne. Accessed January 17, 2021. http://hdl.handle.net/11343/38055.

MLA Handbook (7^th Edition):

TEBRUEGGE, MARC. “Novel approaches to the immunodiagnosis of childhood tuberculosis.” 2012. Web. 17 Jan 2021.

Vancouver:

TEBRUEGGE M. Novel approaches to the immunodiagnosis of childhood tuberculosis. [Internet] [Doctoral dissertation]. University of Melbourne; 2012. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/11343/38055.

Council of Science Editors:

TEBRUEGGE M. Novel approaches to the immunodiagnosis of childhood tuberculosis. [Doctoral Dissertation]. University of Melbourne; 2012. Available from: http://hdl.handle.net/11343/38055

University of Arizona

27. Mitchell, Robert Anthony, 1946-. Construction and evaluation of a directional plasma wave probe .

Degree: 1972, University of Arizona

URL: http://hdl.handle.net/10150/347794

Subjects/Keywords: Plasma diagnostics.

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APA (6^th Edition):

Mitchell, Robert Anthony, 1. (1972). Construction and evaluation of a directional plasma wave probe . (Masters Thesis). University of Arizona. Retrieved from http://hdl.handle.net/10150/347794

Chicago Manual of Style (16^th Edition):

Mitchell, Robert Anthony, 1946-. “Construction and evaluation of a directional plasma wave probe .” 1972. Masters Thesis, University of Arizona. Accessed January 17, 2021. http://hdl.handle.net/10150/347794.

MLA Handbook (7^th Edition):

Mitchell, Robert Anthony, 1946-. “Construction and evaluation of a directional plasma wave probe .” 1972. Web. 17 Jan 2021.

Vancouver:

Mitchell, Robert Anthony 1. Construction and evaluation of a directional plasma wave probe . [Internet] [Masters thesis]. University of Arizona; 1972. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/10150/347794.

Council of Science Editors:

Mitchell, Robert Anthony 1. Construction and evaluation of a directional plasma wave probe . [Masters Thesis]. University of Arizona; 1972. Available from: http://hdl.handle.net/10150/347794

University of Arizona

28. Piejak, Robert Benjamin, 1948-. A cylindrical plasma column with low pressure argon background .

Degree: 1973, University of Arizona

URL: http://hdl.handle.net/10150/554515

Subjects/Keywords: Plasma diagnostics.

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APA (6^th Edition):

Piejak, Robert Benjamin, 1. (1973). A cylindrical plasma column with low pressure argon background . (Masters Thesis). University of Arizona. Retrieved from http://hdl.handle.net/10150/554515

Chicago Manual of Style (16^th Edition):

Piejak, Robert Benjamin, 1948-. “A cylindrical plasma column with low pressure argon background .” 1973. Masters Thesis, University of Arizona. Accessed January 17, 2021. http://hdl.handle.net/10150/554515.

MLA Handbook (7^th Edition):

Piejak, Robert Benjamin, 1948-. “A cylindrical plasma column with low pressure argon background .” 1973. Web. 17 Jan 2021.

Vancouver:

Piejak, Robert Benjamin 1. A cylindrical plasma column with low pressure argon background . [Internet] [Masters thesis]. University of Arizona; 1973. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/10150/554515.

Council of Science Editors:

Piejak, Robert Benjamin 1. A cylindrical plasma column with low pressure argon background . [Masters Thesis]. University of Arizona; 1973. Available from: http://hdl.handle.net/10150/554515

University of North Texas

29. Schmalz, Jonathan. Oh G-d, A Borderline: Clinical Diagnostics As Fundamental Attribution Error.

Degree: 2011, University of North Texas

URL: https://digital.library.unt.edu/ark:/67531/metadc103389/

► Researchers raise concerns that the diagnostic approach can create stigma and lead to clinical inferences that focus on dispositional characteristics at the expense of situational… (more)

Subjects/Keywords: DSM; stigma; diagnostics; attribution error

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APA (6^th Edition):

Schmalz, J. (2011). Oh G-d, A Borderline: Clinical Diagnostics As Fundamental Attribution Error. (Thesis). University of North Texas. Retrieved from https://digital.library.unt.edu/ark:/67531/metadc103389/

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Schmalz, Jonathan. “Oh G-d, A Borderline: Clinical Diagnostics As Fundamental Attribution Error.” 2011. Thesis, University of North Texas. Accessed January 17, 2021. https://digital.library.unt.edu/ark:/67531/metadc103389/.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Schmalz, Jonathan. “Oh G-d, A Borderline: Clinical Diagnostics As Fundamental Attribution Error.” 2011. Web. 17 Jan 2021.

Vancouver:

Schmalz J. Oh G-d, A Borderline: Clinical Diagnostics As Fundamental Attribution Error. [Internet] [Thesis]. University of North Texas; 2011. [cited 2021 Jan 17]. Available from: https://digital.library.unt.edu/ark:/67531/metadc103389/.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Schmalz J. Oh G-d, A Borderline: Clinical Diagnostics As Fundamental Attribution Error. [Thesis]. University of North Texas; 2011. Available from: https://digital.library.unt.edu/ark:/67531/metadc103389/

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Queens University

30. Rezaei, Aida. Multi-sensor besed framework for gear condition monitoring .

Degree: Mechanical and Materials Engineering, 2013, Queens University

URL: http://hdl.handle.net/1974/7988

► In recent years, there has been considerable interest in developing efficient machine diagnostics and prognostics tools for quantitative estimation of systems condition and remaining useful… (more)

▼ In recent years, there has been considerable interest in developing efficient machine diagnostics and prognostics tools for quantitative estimation of systems condition and remaining useful life. Often, it is beneficial to combine several measures into a single feature for machine condition monitoring purposes. Selection of appropriate features represents a key step to satisfy machine condition monitoring requirements. Gearboxes represent one of those complex systems where classification of fault stages and types (diagnostics) and remaining useful life prediction (prognostics) remain a challenging task. This thesis focuses on certain aspects of engineering tribology related to gearbox components diagnostics and prognostics based on multi-sensor measurements. A dynamic large-scale mechanical system test-bed has been designed, built, and commissioned. This apparatus is based on the accessory gearbox of the GE J85 turbojet engine, which operates in a number of aircrafts, such as the Canadair CT-114 Tutor. The test rig is equipped with a high speed data acquisition system along with a variety of sensing technologies such as vibration, sound, and acoustic emission transducers in addition to thermocouples, power cells and loading mechanisms. Various attributes are compared for detecting faulty gears and a non-parametric statistical method is used as a quantitative measure of transmission quality. The feature importance level is determined by the significant difference level; and the independent coefficient of the candidate feature is used to compare and rank different time and frequency features. An optimal feature set is then evaluated using the support vector machine classification method by considering a monotonically increasing classification rate. In addition, the selected feature subset has the potential to achieve a better recognition rate than those selected by other heuristic methods such as the mutual information method. This thesis also introduces two metrics which identify the appropriate prognostic feature: load stability ratio and degradation value. The two criteria can be used to compare candidate prognostic features to determine which are most useful for prognosis. An optimization-based method is then used to obtain the optimal feature. The optimized feature can be used with a degradation path modeling to estimate RUL (remaining useful life) for the specific gear system.

Subjects/Keywords: Condition Monitoring ; Diagnostics ; Prognosis ; Gear

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APA (6^th Edition):

Rezaei, A. (2013). Multi-sensor besed framework for gear condition monitoring . (Thesis). Queens University. Retrieved from http://hdl.handle.net/1974/7988

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Rezaei, Aida. “Multi-sensor besed framework for gear condition monitoring .” 2013. Thesis, Queens University. Accessed January 17, 2021. http://hdl.handle.net/1974/7988.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Rezaei, Aida. “Multi-sensor besed framework for gear condition monitoring .” 2013. Web. 17 Jan 2021.

Vancouver:

Rezaei A. Multi-sensor besed framework for gear condition monitoring . [Internet] [Thesis]. Queens University; 2013. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1974/7988.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Rezaei A. Multi-sensor besed framework for gear condition monitoring . [Thesis]. Queens University; 2013. Available from: http://hdl.handle.net/1974/7988

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Open Access Theses and Dissertations