subject:(damage)

1. Shakiba, Maryam. A Continuum Coupled Moisture-mechanical Constitutive Model for Asphalt Concrete.

Degree: 2013, Texas Digital Library

URL: http://hdl.handle.net/1969; http://hdl.handle.net/2249.1/66856

► The presence and flow of moisture degrade engineering properties of asphalt concrete as part of thermodynamic, chemical, physical, and mechanical processes. This detrimental effect is… (more)

▼ The presence and flow of moisture degrade engineering properties of asphalt concrete as part of thermodynamic, chemical, physical, and mechanical processes. This detrimental effect is referred to as moisture damage. The aim of this dissertation is the development of physically based constitutive relationships along with a computational tool for the fundamental analysis of combined mechanical and moisture induced damage of asphalt concrete. Such a tool can greatly contribute to an improved material selection procedure and give insight into the various damage inducing mechanisms in asphalt concrete. In this dissertation, thermo-hygro-mechanical constitutive relationships are developed based on the principle of virtual power and laws of thermodynamics in order to simulate moisture-induced damage of asphalt concrete. An evolution function is proposed to consider the detrimental effect of moisture diffusion and presence inside the material. The effect of pore water pressure is incorporated using Biot???s coefficient. The Continuum Damage Mechanics (CDM) theory is extended to Continuum Moisture-Mechanical Damage Mechanics (CMMDM) to incorporate the moisture degradation effect and couple it to the mechanical response of asphalt concrete. The proposed moisture damage constitutive relationships are implemented in the Pavement Analysis using Nonlinear Damage Approach (PANDA) finite element (FE) package to model the moisture damage effect on the complex environmental-mechanical response of asphalt concrete. The developed constitutive relationship and framework are validated over different loading scenarios and a range of experimental measurements. The developed constitutive relationship and framework are applied to simulate pavement performance. The focus is on investigating the effects of various moisture conditioning periods on permanent deformation (rutting) and fatigue damage of asphalt pavements. The constitutive and computational models are used to develop a framework for the simulation of the effect of moisture on the microstructural response of asphalt concrete. This framework explicitly incorporates the material microstructural distribution and properties. The developed framework is used to perform two-dimensional (2D) and three-dimensional (3D) micromechanical simulations in order to study and investigate the capability of the proposed constitutive relationships to predict the microstructural response of asphalt concrete under combined effect of moisture diffusion and mechanical loading. Advisors/Committee Members: Little, Dallas (advisor).

Subjects/Keywords: Moisture Damage

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Shakiba, M. (2013). A Continuum Coupled Moisture-mechanical Constitutive Model for Asphalt Concrete. (Thesis). Texas Digital Library. Retrieved from http://hdl.handle.net/1969; http://hdl.handle.net/2249.1/66856

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Shakiba, Maryam. “A Continuum Coupled Moisture-mechanical Constitutive Model for Asphalt Concrete.” 2013. Thesis, Texas Digital Library. Accessed February 26, 2021. http://hdl.handle.net/1969; http://hdl.handle.net/2249.1/66856.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Shakiba, Maryam. “A Continuum Coupled Moisture-mechanical Constitutive Model for Asphalt Concrete.” 2013. Web. 26 Feb 2021.

Vancouver:

Shakiba M. A Continuum Coupled Moisture-mechanical Constitutive Model for Asphalt Concrete. [Internet] [Thesis]. Texas Digital Library; 2013. [cited 2021 Feb 26]. Available from: http://hdl.handle.net/1969; http://hdl.handle.net/2249.1/66856.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Shakiba M. A Continuum Coupled Moisture-mechanical Constitutive Model for Asphalt Concrete. [Thesis]. Texas Digital Library; 2013. Available from: http://hdl.handle.net/1969; http://hdl.handle.net/2249.1/66856

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Hawaii – Manoa

2. Sil, Payel. Role of γ-H2AX in DNA damage response.

Degree: 2016, University of Hawaii – Manoa

URL: http://hdl.handle.net/10125/101438

►

M.S. University of Hawaii at Manoa 2011.

Little is known about the molecular mechanism of γ-H2AX in DNA damage response in mammalian embryos when compared… (more)

Subjects/Keywords: DNA damage

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Sil, P. (2016). Role of γ-H2AX in DNA damage response. (Thesis). University of Hawaii – Manoa. Retrieved from http://hdl.handle.net/10125/101438

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Sil, Payel. “Role of γ-H2AX in DNA damage response.” 2016. Thesis, University of Hawaii – Manoa. Accessed February 26, 2021. http://hdl.handle.net/10125/101438.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Sil, Payel. “Role of γ-H2AX in DNA damage response.” 2016. Web. 26 Feb 2021.

Vancouver:

Sil P. Role of γ-H2AX in DNA damage response. [Internet] [Thesis]. University of Hawaii – Manoa; 2016. [cited 2021 Feb 26]. Available from: http://hdl.handle.net/10125/101438.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Sil P. Role of γ-H2AX in DNA damage response. [Thesis]. University of Hawaii – Manoa; 2016. Available from: http://hdl.handle.net/10125/101438

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Alberta

3. Shivhare, Shishir. A study of the rheology, stability and pore blocking ability of non-aqueous colloidal gas aphron drilling fluids.

Degree: MS, Department of Civil and Environmental Engineering, 2011, University of Alberta

URL: https://era.library.ualberta.ca/files/2b88qc96d

► Colloidal gas aphrons (CGAs) recently used as part of water-based drilling fluids have been found effective in controlling the filtration rate by bridging the pores… (more)

Subjects/Keywords: aphron; formation damage

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Shivhare, S. (2011). A study of the rheology, stability and pore blocking ability of non-aqueous colloidal gas aphron drilling fluids. (Masters Thesis). University of Alberta. Retrieved from https://era.library.ualberta.ca/files/2b88qc96d

Chicago Manual of Style (16^th Edition):

Shivhare, Shishir. “A study of the rheology, stability and pore blocking ability of non-aqueous colloidal gas aphron drilling fluids.” 2011. Masters Thesis, University of Alberta. Accessed February 26, 2021. https://era.library.ualberta.ca/files/2b88qc96d.

MLA Handbook (7^th Edition):

Shivhare, Shishir. “A study of the rheology, stability and pore blocking ability of non-aqueous colloidal gas aphron drilling fluids.” 2011. Web. 26 Feb 2021.

Vancouver:

Shivhare S. A study of the rheology, stability and pore blocking ability of non-aqueous colloidal gas aphron drilling fluids. [Internet] [Masters thesis]. University of Alberta; 2011. [cited 2021 Feb 26]. Available from: https://era.library.ualberta.ca/files/2b88qc96d.

Council of Science Editors:

Shivhare S. A study of the rheology, stability and pore blocking ability of non-aqueous colloidal gas aphron drilling fluids. [Masters Thesis]. University of Alberta; 2011. Available from: https://era.library.ualberta.ca/files/2b88qc96d

Texas A&M University

4. Arastoo, Mahsa. Modeling Micro-Damage Healing Mechanism at Micro-Scale.

Degree: MS, Civil Engineering, 2013, Texas A&M University

URL: http://hdl.handle.net/1969.1/151281

► This thesis demonstrates the effect of micro-damage healing on stress and displacement fields in the vicinity of a crack tip in the material that tend… (more)

▼ This thesis demonstrates the effect of micro-damage healing on stress and displacement fields in the vicinity of a crack tip in the material that tend to self-heal. The micro-damage healing model is modeled by incorporating time-dependent traction within the crack faces. This time-dependent traction occurs in a small zone referred to as healing process zone. The effect of the micro-damage healing on crack propagation in elastic media is investigated by deriving analytical relations for Stress Intensity Factor (SIF) when micro-damage healing mechanism is in effect. It is shown that the larger values of both healing process zone and bonding strength decrease the value of SIF near the crack tip. In order to clearly capture this phenomenon, a novel technique based on complex variables is used to derive the equations to calculate the stress and displacement fields in elastic media. Using the third correspondence principle, which is suitable in analyzing the crack shortening (healing phenomenon), the corresponding results of stress and displacement fields in elastic media are converted into viscoelastic media. Since asphalt has time-dependent material properties, the viscoelastic result is more accurate than the elastic. It is shown that an increase in the value of both healing process zone and bonding strength results in a decrease in the stress and displacement fields near the crack tip. Finally, the effect of using different coefficients in defining the bonding strength and relaxation time is evaluated. Asphalt concrete pavements are concurrently subjected to mechanical and environmental loading conditions during their service life. Applied mechanical and environmental loadings gradually degrade properties of asphalt concrete pavements. However, under specific conditions, asphalt concrete has the potential to heal and regain part of its strength. Identifying a model for the healing process is crucial. This proposed model is not dependent on the test methods that empower its usage in computational modeling. Moreover, this research considers both effects of instantaneous healing (a result of wetting) and time-dependent bond strength (a result of molecular diffusion between the crack faces), using the complex-variable method. Schapery (1989) considered only instantaneous healing and regarded it as the total bond strength. Therefore, considering both effects of instantaneous and time-dependent bond-strength makes this model superior with respect to the analogous model. It is hoped that this research provides insight on the healing mechanism at micro-scale. Advisors/Committee Members: Little, Dallas N. (advisor), Hueste, Mary Beth (committee member), Boas, Harold P. (committee member), Karaman, Ibrahim (committee member), Darabi, Masoud (committee member).

Subjects/Keywords: Micro damage healing

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Arastoo, M. (2013). Modeling Micro-Damage Healing Mechanism at Micro-Scale. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/151281

Chicago Manual of Style (16^th Edition):

Arastoo, Mahsa. “Modeling Micro-Damage Healing Mechanism at Micro-Scale.” 2013. Masters Thesis, Texas A&M University. Accessed February 26, 2021. http://hdl.handle.net/1969.1/151281.

MLA Handbook (7^th Edition):

Arastoo, Mahsa. “Modeling Micro-Damage Healing Mechanism at Micro-Scale.” 2013. Web. 26 Feb 2021.

Vancouver:

Arastoo M. Modeling Micro-Damage Healing Mechanism at Micro-Scale. [Internet] [Masters thesis]. Texas A&M University; 2013. [cited 2021 Feb 26]. Available from: http://hdl.handle.net/1969.1/151281.

Council of Science Editors:

Arastoo M. Modeling Micro-Damage Healing Mechanism at Micro-Scale. [Masters Thesis]. Texas A&M University; 2013. Available from: http://hdl.handle.net/1969.1/151281

Texas A&M University

5. Ghorawat, Sandeep. Rapid Loss Modeling of Death and Downtime Caused By Earthquake Induced Damage to Structures.

Degree: MS, Civil Engineering, 2012, Texas A&M University

URL: http://hdl.handle.net/1969.1/ETD-TAMU-2011-05-9072

► It is important to assess and communicate the risk to life and downtime associated with earthquake induced damage to structures. Thus, a previously developed four-diagram/four-step… (more)

Subjects/Keywords: Damage; Death; Downtime

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Ghorawat, S. (2012). Rapid Loss Modeling of Death and Downtime Caused By Earthquake Induced Damage to Structures. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/ETD-TAMU-2011-05-9072

Chicago Manual of Style (16^th Edition):

Ghorawat, Sandeep. “Rapid Loss Modeling of Death and Downtime Caused By Earthquake Induced Damage to Structures.” 2012. Masters Thesis, Texas A&M University. Accessed February 26, 2021. http://hdl.handle.net/1969.1/ETD-TAMU-2011-05-9072.

MLA Handbook (7^th Edition):

Ghorawat, Sandeep. “Rapid Loss Modeling of Death and Downtime Caused By Earthquake Induced Damage to Structures.” 2012. Web. 26 Feb 2021.

Vancouver:

Ghorawat S. Rapid Loss Modeling of Death and Downtime Caused By Earthquake Induced Damage to Structures. [Internet] [Masters thesis]. Texas A&M University; 2012. [cited 2021 Feb 26]. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2011-05-9072.

Council of Science Editors:

Ghorawat S. Rapid Loss Modeling of Death and Downtime Caused By Earthquake Induced Damage to Structures. [Masters Thesis]. Texas A&M University; 2012. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2011-05-9072

Texas A&M University

6. Cui, Yan. Risk Assessment of Pipeline on Third-Party Damage in Oil and Gas Industry with Bayesian Network and Game Theory.

Degree: MS, Safety Engineering, 2017, Texas A&M University

URL: http://hdl.handle.net/1969.1/161410

► Tremendous amount of oil and gas products are transported in pipeline worldwide giving rise to a demand to identify the hazards and evaluate the associated… (more)

Subjects/Keywords: Third-Party Damage

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Cui, Y. (2017). Risk Assessment of Pipeline on Third-Party Damage in Oil and Gas Industry with Bayesian Network and Game Theory. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/161410

Chicago Manual of Style (16^th Edition):

Cui, Yan. “Risk Assessment of Pipeline on Third-Party Damage in Oil and Gas Industry with Bayesian Network and Game Theory.” 2017. Masters Thesis, Texas A&M University. Accessed February 26, 2021. http://hdl.handle.net/1969.1/161410.

MLA Handbook (7^th Edition):

Cui, Yan. “Risk Assessment of Pipeline on Third-Party Damage in Oil and Gas Industry with Bayesian Network and Game Theory.” 2017. Web. 26 Feb 2021.

Vancouver:

Cui Y. Risk Assessment of Pipeline on Third-Party Damage in Oil and Gas Industry with Bayesian Network and Game Theory. [Internet] [Masters thesis]. Texas A&M University; 2017. [cited 2021 Feb 26]. Available from: http://hdl.handle.net/1969.1/161410.

Council of Science Editors:

Cui Y. Risk Assessment of Pipeline on Third-Party Damage in Oil and Gas Industry with Bayesian Network and Game Theory. [Masters Thesis]. Texas A&M University; 2017. Available from: http://hdl.handle.net/1969.1/161410

Texas A&M University

7. Rady, Ayten Khaled Mohamed Abdelhalim. Formation Damage Due To Iron Precpitation In Limestone, Dolomite and Sandstone Cores.

Degree: MS, Petroleum Engineering, 2016, Texas A&M University

URL: http://hdl.handle.net/1969.1/157118

► Formation damage due to iron precipitation continues to be a major problem in the oil field. Research has established that as the pH of injected… (more)

Subjects/Keywords: iron formation damage

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Rady, A. K. M. A. (2016). Formation Damage Due To Iron Precpitation In Limestone, Dolomite and Sandstone Cores. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/157118

Chicago Manual of Style (16^th Edition):

Rady, Ayten Khaled Mohamed Abdelhalim. “Formation Damage Due To Iron Precpitation In Limestone, Dolomite and Sandstone Cores.” 2016. Masters Thesis, Texas A&M University. Accessed February 26, 2021. http://hdl.handle.net/1969.1/157118.

MLA Handbook (7^th Edition):

Rady, Ayten Khaled Mohamed Abdelhalim. “Formation Damage Due To Iron Precpitation In Limestone, Dolomite and Sandstone Cores.” 2016. Web. 26 Feb 2021.

Vancouver:

Rady AKMA. Formation Damage Due To Iron Precpitation In Limestone, Dolomite and Sandstone Cores. [Internet] [Masters thesis]. Texas A&M University; 2016. [cited 2021 Feb 26]. Available from: http://hdl.handle.net/1969.1/157118.

Council of Science Editors:

Rady AKMA. Formation Damage Due To Iron Precpitation In Limestone, Dolomite and Sandstone Cores. [Masters Thesis]. Texas A&M University; 2016. Available from: http://hdl.handle.net/1969.1/157118

Penn State University

8. Matthews, Peter Joseph. Modeling Continuous-fiber Reinforced Polymer Composites for Exploration of Damage Tolerant Concepts.

Degree: 2015, Penn State University

URL: https://submit-etda.libraries.psu.edu/catalog/25002

► This work aims to improve the predictive capability for fiber-reinforced polymer matrix composite laminates using the finite element method. A new tool for modeling composite… (more)

Subjects/Keywords: composites; delamination; damage

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Matthews, P. J. (2015). Modeling Continuous-fiber Reinforced Polymer Composites for Exploration of Damage Tolerant Concepts. (Thesis). Penn State University. Retrieved from https://submit-etda.libraries.psu.edu/catalog/25002

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Matthews, Peter Joseph. “Modeling Continuous-fiber Reinforced Polymer Composites for Exploration of Damage Tolerant Concepts.” 2015. Thesis, Penn State University. Accessed February 26, 2021. https://submit-etda.libraries.psu.edu/catalog/25002.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Matthews, Peter Joseph. “Modeling Continuous-fiber Reinforced Polymer Composites for Exploration of Damage Tolerant Concepts.” 2015. Web. 26 Feb 2021.

Vancouver:

Matthews PJ. Modeling Continuous-fiber Reinforced Polymer Composites for Exploration of Damage Tolerant Concepts. [Internet] [Thesis]. Penn State University; 2015. [cited 2021 Feb 26]. Available from: https://submit-etda.libraries.psu.edu/catalog/25002.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Matthews PJ. Modeling Continuous-fiber Reinforced Polymer Composites for Exploration of Damage Tolerant Concepts. [Thesis]. Penn State University; 2015. Available from: https://submit-etda.libraries.psu.edu/catalog/25002

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Adelaide

9. Nguyen, Thi Kim Phuong. Reservoir simulation studies of formation damage for improved recovery on oil-gas reservoirs.

Degree: 2011, University of Adelaide

URL: http://hdl.handle.net/2440/70889

► This thesis is dedicated to the development of new technologies for sweep improvement due to plugging of highly permeable channels and layers by injected or… (more)

▼ This thesis is dedicated to the development of new technologies for sweep improvement due to plugging of highly permeable channels and layers by injected or lifted or mobilized fines particles. The following methods of improved waterflood have been proposed in the thesis: • Injection of raw or poorly treated water with consequent homogenization of the injectivity profile due to distributed along the well skin factor. • Injection of low salinity or fresh water resulting in lifting of reservoir fines, their migration and further capture by the rock with permeability reduction and redirection of the injected water into unswept area. • Injection of sweet water into watered-up abandoned wells during pressure blowdown in oil and gas reservoirs with strong water support. In the above three cases, the proposal of the new technologies was backed by detailed reservoir simulations. In all cases, the application of the proposed improved oil recovery technology, as forecasted by reservoir simulation, leads to 3-15% of incremental recovery and 2-3 times decrease of the amount of produced and injected water. The technology of raw water injection was developed using Eclipse waterflood BlackOil simulator with modelling of injectivity decline along the well due to plugging of porous media by injected particles. A new numerical procedure describing skin growth with time in each section of long horizontal wells have been developed and implemented into BlackOil Eclipse model. Different configurations of horizontal injectors and producers have been modelled resulting in production forecast with raw waterflooding. The technology of low salinity water injection have been developed using Eclipse reservoir modelling with polymer injection option, which can describe mobilization of fines particles, their migration, capture and subsequent permeability decline. The main physics mechanism of incremental oil recovery found is the diversion of the injected water into unswept zones due to plugging the swept zone by capture particles. The incremental recovery, as obtained by reservoir simulation, is 12%. It may also result in 2 to 3 times decrease in water injection and production. The proposal of a new technology of small bank of fresh water injection into watered-up and abandoned production wells result in lifting of reservoir fines, their migration and plugging the path for invaded aquifer water. It results in decrease of water production and prolongation of oil or gas production from wells. Advisors/Committee Members: Bedrikovetski, Pavel (advisor), Haghighi, Manouchehr (advisor), Australian School of Petroleum (school).

Subjects/Keywords: simulations; formation damage

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Nguyen, T. K. P. (2011). Reservoir simulation studies of formation damage for improved recovery on oil-gas reservoirs. (Thesis). University of Adelaide. Retrieved from http://hdl.handle.net/2440/70889

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Nguyen, Thi Kim Phuong. “Reservoir simulation studies of formation damage for improved recovery on oil-gas reservoirs.” 2011. Thesis, University of Adelaide. Accessed February 26, 2021. http://hdl.handle.net/2440/70889.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Nguyen, Thi Kim Phuong. “Reservoir simulation studies of formation damage for improved recovery on oil-gas reservoirs.” 2011. Web. 26 Feb 2021.

Vancouver:

Nguyen TKP. Reservoir simulation studies of formation damage for improved recovery on oil-gas reservoirs. [Internet] [Thesis]. University of Adelaide; 2011. [cited 2021 Feb 26]. Available from: http://hdl.handle.net/2440/70889.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Nguyen TKP. Reservoir simulation studies of formation damage for improved recovery on oil-gas reservoirs. [Thesis]. University of Adelaide; 2011. Available from: http://hdl.handle.net/2440/70889

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Baylor University

10. Campbell, Abbey M., 1991-. Damage accumulation of bovine bone under variable amplitude loads.

Degree: M.S.B.M.E., Baylor University. School of Engineering., 2016, Baylor University

URL: http://hdl.handle.net/2104/9650

► Stress fractures, a painful injury, are caused by excessive fatigue in bone. This study into damage accumulation in bone sought to determine if the Palmgren-Miner… (more)

Subjects/Keywords: Bone. Fatigue. Damage.

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Campbell, Abbey M., 1. (2016). Damage accumulation of bovine bone under variable amplitude loads. (Masters Thesis). Baylor University. Retrieved from http://hdl.handle.net/2104/9650

Chicago Manual of Style (16^th Edition):

Campbell, Abbey M., 1991-. “Damage accumulation of bovine bone under variable amplitude loads.” 2016. Masters Thesis, Baylor University. Accessed February 26, 2021. http://hdl.handle.net/2104/9650.

MLA Handbook (7^th Edition):

Campbell, Abbey M., 1991-. “Damage accumulation of bovine bone under variable amplitude loads.” 2016. Web. 26 Feb 2021.

Vancouver:

Campbell, Abbey M. 1. Damage accumulation of bovine bone under variable amplitude loads. [Internet] [Masters thesis]. Baylor University; 2016. [cited 2021 Feb 26]. Available from: http://hdl.handle.net/2104/9650.

Council of Science Editors:

Campbell, Abbey M. 1. Damage accumulation of bovine bone under variable amplitude loads. [Masters Thesis]. Baylor University; 2016. Available from: http://hdl.handle.net/2104/9650

Central Connecticut State University

11. Orlinski, Agata W. (Agata Weronika), 1991-. A Prebiotic method toward mitigation of UVB-induced DNA damage, analyzed through CPD detection.

Degree: Department of Chemistry and Biochemistry, 2016, Central Connecticut State University

URL: http://content.library.ccsu.edu/u?/ccsutheses,2343

►

Research on the origin of biological life on Earth is actively working toward understanding the conditions under which possible prebiotic chemical reactions could promote abiogenesis.… (more)

▼

Research on the origin of biological life on Earth is actively working toward understanding the conditions under which possible prebiotic chemical reactions could promote abiogenesis. Cyclobutane pyrimidine dimer (CPD) is the main reaction product of UVB-induced photochemistry on DNA. The presence of a wall, behind which DNA is encapsulated, serves as a necessary boundary and energy exchange system between the interior of a cell and surrounding environment. It is presently undetermined how primitive genetic polymers were protected on early Earth, but naturally occurring molecules present >3.4 Ga ago may have had a role. At that age, the synthesis of organic monomers likely occurred at interfaces between energy and environment. The reducing atmosphere (electron rich) enabled molecules to gain electrons to transduce energy. Since modern membrane-bound molecules that contribute to the movement of electrons in photosynthesis - and have energy transducing properties - contain conjugated ring systems, (PAH) polycyclic aromatic hydrocarbons may have exerted a prebiotic role in redox chemistry. This work aimed to evaluate the effect of a cell model (a vesicle) containing a possible primitive chromophore (here, pyrene) on DNA mutagenesis. An immunochemical assay was used to detect CPDs, formed between adjacent thymine nucleobases on fragmented genomic DNA and induced by UVB light, when DNA was encapsulated in a membrane composed of phospholipid alone or phospholipid and pyrene. These simulations were compared to DNA not encapsulated in a membrane. Results demonstrate that higher overall detection of CPD-DNA correlates with a greater initial rate of CPD-DNA formation. Mainly, the largest rate corresponded to DNA in solution, while the slowest rate corresponded to DNA encapsulated within a (DOPy) DOPC + pyrene membrane.

"Submitted in Partial Fulfillment of the Requirements for the Degree of Master of Arts in Biomolecular Sciences."; Thesis advisor: Sarah E. Maurer.; M.A.,Central Connecticut State University,,2016.;

Advisors/Committee Members: Maurer, Sarah E..

Subjects/Keywords: DNA damage – Prevention.

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Orlinski, Agata W. (Agata Weronika), 1. (2016). A Prebiotic method toward mitigation of UVB-induced DNA damage, analyzed through CPD detection. (Thesis). Central Connecticut State University. Retrieved from http://content.library.ccsu.edu/u?/ccsutheses,2343

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Orlinski, Agata W. (Agata Weronika), 1991-. “A Prebiotic method toward mitigation of UVB-induced DNA damage, analyzed through CPD detection.” 2016. Thesis, Central Connecticut State University. Accessed February 26, 2021. http://content.library.ccsu.edu/u?/ccsutheses,2343.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Orlinski, Agata W. (Agata Weronika), 1991-. “A Prebiotic method toward mitigation of UVB-induced DNA damage, analyzed through CPD detection.” 2016. Web. 26 Feb 2021.

Vancouver:

Orlinski, Agata W. (Agata Weronika) 1. A Prebiotic method toward mitigation of UVB-induced DNA damage, analyzed through CPD detection. [Internet] [Thesis]. Central Connecticut State University; 2016. [cited 2021 Feb 26]. Available from: http://content.library.ccsu.edu/u?/ccsutheses,2343.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Orlinski, Agata W. (Agata Weronika) 1. A Prebiotic method toward mitigation of UVB-induced DNA damage, analyzed through CPD detection. [Thesis]. Central Connecticut State University; 2016. Available from: http://content.library.ccsu.edu/u?/ccsutheses,2343

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Illinois – Urbana-Champaign

12. Shanley, IV, John Francis. In vitro simulation of torque-induced rotator cuff damage.

Degree: MS, Mechanical Engineering, 2018, University of Illinois – Urbana-Champaign

URL: http://hdl.handle.net/2142/101082

► Various aspects of rotator cuff tears have been studied in depth, including the primary pathogenesis and mechanical properties. There is, however, a lack of information… (more)

Subjects/Keywords: Rotator Cuff; Damage

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Shanley, IV, J. F. (2018). In vitro simulation of torque-induced rotator cuff damage. (Thesis). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/101082

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Shanley, IV, John Francis. “In vitro simulation of torque-induced rotator cuff damage.” 2018. Thesis, University of Illinois – Urbana-Champaign. Accessed February 26, 2021. http://hdl.handle.net/2142/101082.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Shanley, IV, John Francis. “In vitro simulation of torque-induced rotator cuff damage.” 2018. Web. 26 Feb 2021.

Vancouver:

Shanley, IV JF. In vitro simulation of torque-induced rotator cuff damage. [Internet] [Thesis]. University of Illinois – Urbana-Champaign; 2018. [cited 2021 Feb 26]. Available from: http://hdl.handle.net/2142/101082.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Shanley, IV JF. In vitro simulation of torque-induced rotator cuff damage. [Thesis]. University of Illinois – Urbana-Champaign; 2018. Available from: http://hdl.handle.net/2142/101082

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Rutgers University

13. Patel, Mihir V., 1987-. The roles of postsynaptic density-95 interactors in dendrite development and recovery after traumatic brain injury.

Degree: PhD, Neuroscience, 2018, Rutgers University

URL: https://rucore.libraries.rutgers.edu/rutgers-lib/59121/

►

Postsynaptic density 95 (PSD-95) is the major scaffolding protein at excitatory synapses, and it plays a major role in synaptic plasticity. Furthermore, PSD-95 and its… (more)

▼

Postsynaptic density 95 (PSD-95) is the major scaffolding protein at excitatory synapses, and it plays a major role in synaptic plasticity. Furthermore, PSD-95 and its interactor, cytosolic PSD-95 interactor (cypin), regulate dendrite branching by altering microtubule dynamics. Additionally, other PSD-95 binding proteins, end-binding protein 3 (EB3) and adenomatous polyposis coli (APC), promote microtubule bundling and stabilization. Thus, PSD-95 and binding partners may regulate the dendritic arbor during development and after injury. I first addressed the role of cypin in the brain in vivo. While generating cypin knockout mice, I identified a novel short isoform of cypin, termed cypinS, which also binds to PSD-95 and regulates dendrite branching, although an increase in dendrites occur more distal from the soma when cypinS is overexpressed compared to when cypin is overexpressed. In addition, unlike cypin, cypinS does not have guanine deaminase activity. Overexpression of cypin, but not cypinS, decreases spine density, suggestingiv that the regulation of spine density but not dendrite branching by cypin is dependent on guanine deaminase activity. Furthermore, I have uncovered novel presynaptic roles for both isoforms as overexpression of either isoform leads to increases in miniature excitatory postsynaptic current (mEPSC) frequency. Thus, cypin and cypinS, play distinct roles in neuronal development. I then chose to study the roles of PSD-95 and interactors in recovery after traumatic brain injury (TBI). We previously identified cypin as a novel target for TBI, and thus, here I studied the role of PSD-95 and its interaction with APC or EB3 in after injury induced by in vitro and in vivo models of TBI. I show that our in vitro model of mechanical stretch injury mimics moderate injury induced by controlled cortical impact (CCI) in mice. During the early stage (1-7 days) post-moderate CCI, the interaction of PSD-95 with APC and EB3 increases. Furthermore, downregulation of PSD-95 prevents stretch-injury mediated decreases in secondary dendrite number and total dendrite length, suggesting a required role of PSD-95 in injury-mediated insults to dendrites. Thus, PSD-95 may sequester APC and EB3 from microtubules to cause decreases in dendrite branching after TBI, and PSD-95 can be targeted as a novel approach for the treatment of patients with TBI.

Advisors/Committee Members: Firestein, Bonnie L (chair), Shumyatsky, Gleb (internal member), Alder, Janet (internal member), D’Arcangelo, Gabriella (internal member), Runnels, Loren (outside member), School of Graduate Studies.

Subjects/Keywords: Dendrites; Brain damage

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Patel, Mihir V., 1. (2018). The roles of postsynaptic density-95 interactors in dendrite development and recovery after traumatic brain injury. (Doctoral Dissertation). Rutgers University. Retrieved from https://rucore.libraries.rutgers.edu/rutgers-lib/59121/

Chicago Manual of Style (16^th Edition):

Patel, Mihir V., 1987-. “The roles of postsynaptic density-95 interactors in dendrite development and recovery after traumatic brain injury.” 2018. Doctoral Dissertation, Rutgers University. Accessed February 26, 2021. https://rucore.libraries.rutgers.edu/rutgers-lib/59121/.

MLA Handbook (7^th Edition):

Patel, Mihir V., 1987-. “The roles of postsynaptic density-95 interactors in dendrite development and recovery after traumatic brain injury.” 2018. Web. 26 Feb 2021.

Vancouver:

Patel, Mihir V. 1. The roles of postsynaptic density-95 interactors in dendrite development and recovery after traumatic brain injury. [Internet] [Doctoral dissertation]. Rutgers University; 2018. [cited 2021 Feb 26]. Available from: https://rucore.libraries.rutgers.edu/rutgers-lib/59121/.

Council of Science Editors:

Patel, Mihir V. 1. The roles of postsynaptic density-95 interactors in dendrite development and recovery after traumatic brain injury. [Doctoral Dissertation]. Rutgers University; 2018. Available from: https://rucore.libraries.rutgers.edu/rutgers-lib/59121/

University of Adelaide

14. Arjomand, Elaheh. Cement Sheath Integrity Assessment Subject to Pressure and Temperature Variations.

Degree: 2018, University of Adelaide

URL: http://hdl.handle.net/2440/120307

► The exploration and exploitation of hydrocarbon wells should not cause any environmental hazards including contamination of groundwater (aquifers) and atmosphere. The cement placed in the… (more)

▼ The exploration and exploitation of hydrocarbon wells should not cause any environmental hazards including contamination of groundwater (aquifers) and atmosphere. The cement placed in the annular gaps between the casing strings and the formation acts as a key barrier to provide zonal isolation and maintain the integrity of the wells. The integrity of the cement sheath and the cement sheath interfaces is susceptible to be compromised during well operational processes, including but not limited to, pressure integrity tests (PIT), completion operations, stimulation treatments, and production processes. The cement sheath may experience different types of mechanical damage as a result of being exposed to these different wellbore operational procedures. Therefore, understanding of cement failure mechanisms is of the utmost importance for better assessments of wellbore integrity. This thesis demonstrates the results of the experimental-numerical studies and investigates the integrity of the cement sheaths subjected to pressure and temperature variations. The overall purpose of this study is to improve the modelling capabilities of cement sheath integrity assessments by employing a more comprehensive constitutive model for the cement sheath compared to the rest of the models previously used. The experimental studies on the behaviour of the cement-based specimens under compression tests showed a strong non-linearity in the obtained stress-strain curves which confirms the necessity of applying plasticity theories. However, it is hard to explain the elastic stiffness degradation of the cement-based materials which happens during experiments using the classical plasticity theories. Therefore, in this thesis, the modified Concrete Damage Plasticity (CDP) model was employed, particularly formulated for modelling geo-materials such as rocks, concrete, and cementitious materials. The Concrete Damage Plasticity is a continuum model which combines plasticity and damage mechanisms, considering two different tensile and compressive state of damage. The yield criterion in the CDP model also represents the pressure-dependency of the geo-material behaviour under shearing at different levels of confinement in addition to the incorporation of non-associated flow rule (material dilatancy). These features show the superiority of the CDP model for employing in cement sheath integrity assessments. However, the paucity of cement class G mechanical parameters, e.g. lack of experimental data under different confining pressure and tensile properties, was an impediment to the incorporation of Concrete Damage Plasticity model. Therefore, the experimental aspect of this study intends to expand the cement class G inventory. The experimental data and analyses added to inventory are as followed. The investigations of curing temperature and pressure confinements effects on the strength and post-peak response of the cement class G under compression and also obtaining cement tensile properties. The experimental results show by increasing the curing… Advisors/Committee Members: School of Civil, Environmental and Mining Engineering (school).

Subjects/Keywords: Cement sheath integrity; concrete damage plasticity model; compression damage; tensile damage

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Arjomand, E. (2018). Cement Sheath Integrity Assessment Subject to Pressure and Temperature Variations. (Thesis). University of Adelaide. Retrieved from http://hdl.handle.net/2440/120307

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Arjomand, Elaheh. “Cement Sheath Integrity Assessment Subject to Pressure and Temperature Variations.” 2018. Thesis, University of Adelaide. Accessed February 26, 2021. http://hdl.handle.net/2440/120307.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Arjomand, Elaheh. “Cement Sheath Integrity Assessment Subject to Pressure and Temperature Variations.” 2018. Web. 26 Feb 2021.

Vancouver:

Arjomand E. Cement Sheath Integrity Assessment Subject to Pressure and Temperature Variations. [Internet] [Thesis]. University of Adelaide; 2018. [cited 2021 Feb 26]. Available from: http://hdl.handle.net/2440/120307.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Arjomand E. Cement Sheath Integrity Assessment Subject to Pressure and Temperature Variations. [Thesis]. University of Adelaide; 2018. Available from: http://hdl.handle.net/2440/120307

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Johannesburg

15. Capitani, Gina Maria. Longterm outcome after traumatic brain injury : neurological status and adjustment.

Degree: 2012, University of Johannesburg

URL: http://hdl.handle.net/10210/6892

►

D.Litt. et. Phil.

Head injury is the major cause of death for individuals under 35 years old in the United States of America, and a… (more)

▼

D.Litt. et. Phil.

Head injury is the major cause of death for individuals under 35 years old in the United States of America, and a similar picture exists in South Africa. A major cause of traumatic brain injury is motor vehicle accidents. In addition, the advances in modem medical technology increase the chances for survival, for example, sophisticated medical diagnostic techniques such as computerised tomography (CT), and magnetic resonance imaging (MRI). Advances in emergency trauma and neurosurgical procedures have also increased the number of survivors following a head injury. The symptoms resulting from head injury include disturbed physical, cognitive, psychological and behavioural functioning. Long-term management of these symptoms is usually required. A body of evidence exists that demonstrates the value of rehabilitation during the first year of recovery from traumatic brain injury. Head injury cases often result in litigation in that the injured person may be entitled to compensation for the injuries sustained. Considerable forensic debate exists around the issue of whether the victim's symptoms are attributable to organic brain damage, or whether they reflect a pre-existing functional psychological state of psychiatric illness, or personality disorder. Further still, the individual may be 'malingering' or faking postconcussion symptoms of headache, dizziness, fatigue, memory deficit, impaired concentration, irritability, anxiety, insomnia, concern about bodily functions, and hypersensitivity to light and noise. Alternatively, a common diagnosis is traumatic neurosis with a psychogenic basis, and in the context of litigation is referred to as "compensation neurosis". Specifically, the issue of contention revolves around concussion, and mild or minor head injuries. This study proposed that both neuropathophysiological and psychosocial symptoms occur in the event of a traumatic brain injury. This view supports the traditional model that pain or the sequelae of head injury are not affected by compensation. Therefore, the objective of the study was that follow-up assessment after compensation pay-outs should produce similar results to the assessment results obtained during the litigation process. The hypotheses of the study were essentially confirmed. The neuropsychological error scores produced in the assessments during litigation, and two-to-four years after the completion of litigation were similar. However, similar to other studies, variations were evident. Four exceptions were demonstrated in that significant improvement was evident with regard to shotterm verbal memory delayed recall for paragraphs, and for immediate recall (without and after interference) in verbal memory for a word list. These improvements therefore pertain to verbal memory. The fourth improvement occurred with respect to manual dexterity and visual-motor work speed, although the improvement may be peripheral or primary (neurological). Further findings included that no gender differences were evident in the neuropsychological…

Subjects/Keywords: Brain damage - Patients - Rehabilitation; Brain damage - Patients - Rehabilitation - Evaluation; Brain damage - Patients - Mental health; Neuropsychology

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Capitani, G. M. (2012). Longterm outcome after traumatic brain injury : neurological status and adjustment. (Thesis). University of Johannesburg. Retrieved from http://hdl.handle.net/10210/6892

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Capitani, Gina Maria. “Longterm outcome after traumatic brain injury : neurological status and adjustment.” 2012. Thesis, University of Johannesburg. Accessed February 26, 2021. http://hdl.handle.net/10210/6892.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Capitani, Gina Maria. “Longterm outcome after traumatic brain injury : neurological status and adjustment.” 2012. Web. 26 Feb 2021.

Vancouver:

Capitani GM. Longterm outcome after traumatic brain injury : neurological status and adjustment. [Internet] [Thesis]. University of Johannesburg; 2012. [cited 2021 Feb 26]. Available from: http://hdl.handle.net/10210/6892.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Capitani GM. Longterm outcome after traumatic brain injury : neurological status and adjustment. [Thesis]. University of Johannesburg; 2012. Available from: http://hdl.handle.net/10210/6892

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of New Mexico

16. Pelka, Sara M. Examination of color center formation in CaF2 crystals when exposed to gamma and mixed neutron/gamma fields.

Degree: Nuclear Engineering, 2017, University of New Mexico

URL: https://digitalrepository.unm.edu/ne_etds/61

► Color centers in CaF₂ were studied in this work, in parallel with examinations of changes in the refractive index of the crystals by the… (more)

Subjects/Keywords: color center; material damage; CaF2; neutron damage; gamma damage; F center; Nuclear Engineering

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Pelka, S. M. (2017). Examination of color center formation in CaF2 crystals when exposed to gamma and mixed neutron/gamma fields. (Masters Thesis). University of New Mexico. Retrieved from https://digitalrepository.unm.edu/ne_etds/61

Chicago Manual of Style (16^th Edition):

Pelka, Sara M. “Examination of color center formation in CaF2 crystals when exposed to gamma and mixed neutron/gamma fields.” 2017. Masters Thesis, University of New Mexico. Accessed February 26, 2021. https://digitalrepository.unm.edu/ne_etds/61.

MLA Handbook (7^th Edition):

Pelka, Sara M. “Examination of color center formation in CaF2 crystals when exposed to gamma and mixed neutron/gamma fields.” 2017. Web. 26 Feb 2021.

Vancouver:

Pelka SM. Examination of color center formation in CaF2 crystals when exposed to gamma and mixed neutron/gamma fields. [Internet] [Masters thesis]. University of New Mexico; 2017. [cited 2021 Feb 26]. Available from: https://digitalrepository.unm.edu/ne_etds/61.

Council of Science Editors:

Pelka SM. Examination of color center formation in CaF2 crystals when exposed to gamma and mixed neutron/gamma fields. [Masters Thesis]. University of New Mexico; 2017. Available from: https://digitalrepository.unm.edu/ne_etds/61

Oregon State University

17. Song, Yang. The function of zinc in the maintenance of DNA integrity in vivo.

Degree: PhD, Nutrition, 2009, Oregon State University

URL: http://hdl.handle.net/1957/11715

► Approximately 12% of Americans do not consume the amount of zinc equal to the Estimated Average Requirement for zinc and could be at risk for… (more)

▼ Approximately 12% of Americans do not consume the amount of zinc equal to the Estimated Average Requirement for zinc and could be at risk for marginal zinc deficiency. Zinc is an essential component of proteins in the defense against oxidative stress and DNA damage repair. Specifically in the prostate, zinc concentrations are inversely associated with prostate malignancy. Zinc deficiency may predispose cells to the development of cancer by increasing oxidative stress and DNA damage. Studies have shown that severe zinc-depletion increased DNA damage in testes. However, the effects of marginal zinc deficiency, which is more prevalent in human population and physiologically relevant, are understudied. This study aimed to specify the mechanisms by which zinc status affects DNA integrity and the prostate maintains zinc level in vivo. We examined the effects of zinc deficiency on DNA damage and oxidative stress in rat models and in human studies. In rats, severe zinc-depletion caused an increase in DNA damage in peripheral blood cells that decreased following zinc-repletion. DNA repair functions were impaired as indicated by compromised p53 DNA binding and differential activation of DNA repair proteins. Importantly, marginal zinc-depletion (MZD) also increased DNA damage and oxidative stress, and impaired DNA repair functions. However, these effects were not observed in the prostate. Only in combination with an exogenous stress (exercise), MZD increased DNA damage in the prostate, indicating that MZD may sensitize the prostate to exogenous DNA damaging agents. Similar to the rat study, marginal dietary zinc depletion (6wk) in healthy males increased DNA strand breaks in peripheral blood cells, alterations which were ameliorated by zinc repletion (4wk). Oxidative stress and antioxidants were not altered during zinc depletion/repletion periods. The increases in DNA damage were associated with impaired zinc homeostasis. MZD decreased zinc concentration as well as ZnT2 expression in the prostate dorsolateral lobe, indicating disregulation of zinc transporter and zinc homeostasis. Taken together, these studies suggest a key function of zinc in maintaining DNA integrity. Thus, the maintenance of adequate dietary zinc may have an important impact on protecting tissues, such as the prostate, from DNA damage and decreasing cancer risk. Advisors/Committee Members: Ho, Emily (advisor), Traber, Maret G (committee member).

Subjects/Keywords: DNA damage; Zinc deficiency diseases

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Song, Y. (2009). The function of zinc in the maintenance of DNA integrity in vivo. (Doctoral Dissertation). Oregon State University. Retrieved from http://hdl.handle.net/1957/11715

Chicago Manual of Style (16^th Edition):

Song, Yang. “The function of zinc in the maintenance of DNA integrity in vivo.” 2009. Doctoral Dissertation, Oregon State University. Accessed February 26, 2021. http://hdl.handle.net/1957/11715.

MLA Handbook (7^th Edition):

Song, Yang. “The function of zinc in the maintenance of DNA integrity in vivo.” 2009. Web. 26 Feb 2021.

Vancouver:

Song Y. The function of zinc in the maintenance of DNA integrity in vivo. [Internet] [Doctoral dissertation]. Oregon State University; 2009. [cited 2021 Feb 26]. Available from: http://hdl.handle.net/1957/11715.

Council of Science Editors:

Song Y. The function of zinc in the maintenance of DNA integrity in vivo. [Doctoral Dissertation]. Oregon State University; 2009. Available from: http://hdl.handle.net/1957/11715

University of Alberta

18. Campbell, Stuart D. A role for Polycomb Repressive Complex 2 in the DNA damage response.

Degree: MS, Department of Oncology, 2012, University of Alberta

URL: https://era.library.ualberta.ca/files/08612n79r

► Polycomb protein methyltransferase, Enhancer of Zeste 2 (Ezh2), is frequently overexpressed in human malignancy and is implicated in cancer cell proliferation and invasion. Recently, several… (more)

Subjects/Keywords: cancer; DNA damage; polycomb

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Campbell, S. D. (2012). A role for Polycomb Repressive Complex 2 in the DNA damage response. (Masters Thesis). University of Alberta. Retrieved from https://era.library.ualberta.ca/files/08612n79r

Chicago Manual of Style (16^th Edition):

Campbell, Stuart D. “A role for Polycomb Repressive Complex 2 in the DNA damage response.” 2012. Masters Thesis, University of Alberta. Accessed February 26, 2021. https://era.library.ualberta.ca/files/08612n79r.

MLA Handbook (7^th Edition):

Campbell, Stuart D. “A role for Polycomb Repressive Complex 2 in the DNA damage response.” 2012. Web. 26 Feb 2021.

Vancouver:

Campbell SD. A role for Polycomb Repressive Complex 2 in the DNA damage response. [Internet] [Masters thesis]. University of Alberta; 2012. [cited 2021 Feb 26]. Available from: https://era.library.ualberta.ca/files/08612n79r.

Council of Science Editors:

Campbell SD. A role for Polycomb Repressive Complex 2 in the DNA damage response. [Masters Thesis]. University of Alberta; 2012. Available from: https://era.library.ualberta.ca/files/08612n79r

19. La Ode Muhammad Muchdar Davis. Studies on DNA damage response during lateral root formation in Arabidopsis thaliana : シロイヌナズナの側根形成におけるDNA損傷応答に関する研究; シロイヌナズナノソッコンケイセイニオケル DNA ソンショウオウトウニカンスルケンキュウ.

Degree: 博士(バイオサイエンス), Nara Institute of Science and Technology / 奈良先端科学技術大学院大学

URL: http://hdl.handle.net/10061/10989

Subjects/Keywords: DNA damage

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Davis, L. O. M. M. (n.d.). Studies on DNA damage response during lateral root formation in Arabidopsis thaliana : シロイヌナズナの側根形成におけるDNA損傷応答に関する研究; シロイヌナズナノソッコンケイセイニオケル DNA ソンショウオウトウニカンスルケンキュウ. (Thesis). Nara Institute of Science and Technology / 奈良先端科学技術大学院大学. Retrieved from http://hdl.handle.net/10061/10989

Note: this citation may be lacking information needed for this citation format:
No year of publication.
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Davis, La Ode Muhammad Muchdar. “Studies on DNA damage response during lateral root formation in Arabidopsis thaliana : シロイヌナズナの側根形成におけるDNA損傷応答に関する研究; シロイヌナズナノソッコンケイセイニオケル DNA ソンショウオウトウニカンスルケンキュウ.” Thesis, Nara Institute of Science and Technology / 奈良先端科学技術大学院大学. Accessed February 26, 2021. http://hdl.handle.net/10061/10989.

Note: this citation may be lacking information needed for this citation format:
No year of publication.
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Davis, La Ode Muhammad Muchdar. “Studies on DNA damage response during lateral root formation in Arabidopsis thaliana : シロイヌナズナの側根形成におけるDNA損傷応答に関する研究; シロイヌナズナノソッコンケイセイニオケル DNA ソンショウオウトウニカンスルケンキュウ.” Web. 26 Feb 2021.

Note: this citation may be lacking information needed for this citation format:
No year of publication.

Vancouver:

Davis LOMM. Studies on DNA damage response during lateral root formation in Arabidopsis thaliana : シロイヌナズナの側根形成におけるDNA損傷応答に関する研究; シロイヌナズナノソッコンケイセイニオケル DNA ソンショウオウトウニカンスルケンキュウ. [Internet] [Thesis]. Nara Institute of Science and Technology / 奈良先端科学技術大学院大学; [cited 2021 Feb 26]. Available from: http://hdl.handle.net/10061/10989.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
No year of publication.

Council of Science Editors:

Davis LOMM. Studies on DNA damage response during lateral root formation in Arabidopsis thaliana : シロイヌナズナの側根形成におけるDNA損傷応答に関する研究; シロイヌナズナノソッコンケイセイニオケル DNA ソンショウオウトウニカンスルケンキュウ. [Thesis]. Nara Institute of Science and Technology / 奈良先端科学技術大学院大学; Available from: http://hdl.handle.net/10061/10989

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
No year of publication.

20. Chen, Po-Yu. Studies of DNA damage response in Arabidopsis roots : シロイヌナズナの根におけるDNA損傷応答に関する研究; シロイヌナズナノネニオケル DNA ソンショウオウトウニカンスルケンキュウ.

Degree: 博士(バイオサイエンス), Nara Institute of Science and Technology / 奈良先端科学技術大学院大学

URL: http://hdl.handle.net/10061/10078

Subjects/Keywords: DNA damage

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Chen, P. (n.d.). Studies of DNA damage response in Arabidopsis roots : シロイヌナズナの根におけるDNA損傷応答に関する研究; シロイヌナズナノネニオケル DNA ソンショウオウトウニカンスルケンキュウ. (Thesis). Nara Institute of Science and Technology / 奈良先端科学技術大学院大学. Retrieved from http://hdl.handle.net/10061/10078

Note: this citation may be lacking information needed for this citation format:
No year of publication.
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Chen, Po-Yu. “Studies of DNA damage response in Arabidopsis roots : シロイヌナズナの根におけるDNA損傷応答に関する研究; シロイヌナズナノネニオケル DNA ソンショウオウトウニカンスルケンキュウ.” Thesis, Nara Institute of Science and Technology / 奈良先端科学技術大学院大学. Accessed February 26, 2021. http://hdl.handle.net/10061/10078.

Note: this citation may be lacking information needed for this citation format:
No year of publication.
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Chen, Po-Yu. “Studies of DNA damage response in Arabidopsis roots : シロイヌナズナの根におけるDNA損傷応答に関する研究; シロイヌナズナノネニオケル DNA ソンショウオウトウニカンスルケンキュウ.” Web. 26 Feb 2021.

Note: this citation may be lacking information needed for this citation format:
No year of publication.

Vancouver:

Chen P. Studies of DNA damage response in Arabidopsis roots : シロイヌナズナの根におけるDNA損傷応答に関する研究; シロイヌナズナノネニオケル DNA ソンショウオウトウニカンスルケンキュウ. [Internet] [Thesis]. Nara Institute of Science and Technology / 奈良先端科学技術大学院大学; [cited 2021 Feb 26]. Available from: http://hdl.handle.net/10061/10078.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
No year of publication.

Council of Science Editors:

Chen P. Studies of DNA damage response in Arabidopsis roots : シロイヌナズナの根におけるDNA損傷応答に関する研究; シロイヌナズナノネニオケル DNA ソンショウオウトウニカンスルケンキュウ. [Thesis]. Nara Institute of Science and Technology / 奈良先端科学技術大学院大学; Available from: http://hdl.handle.net/10061/10078

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
No year of publication.

University of Tasmania

21. Little, Jason Stuart. Change in electrophysiological correlates of recognition memory processes following mild traumatic brain injury.

Degree: 2010, University of Tasmania

URL: https://eprints.utas.edu.au/20758/1/whole_LittleJasonStuart2010_thesis.pdf

► There is a considerable body of evidence showing the presence of long term change in electrophysiological correlates of attentional processes following mild traumatic brain injury… (more)

▼ There is a considerable body of evidence showing the presence of long term change in electrophysiological correlates of attentional processes following mild traumatic brain injury (MTBI). As well there is a large body of research demonstrating impairment in cognitive functioning, including memory and attention processes, in the acute stage following MTBI. However, to date there has been little research investigating long term change in electrophysiological correlates of memory function following MTBI. More specifically, there is virtually no research investigating long term change in electrophysiological correlates of recognition memory function following MTBI. Therefore the present research aimed to investigate the electrophysiological correlates of recognition memory processes in males who had suffered an MTI3I. Event related potentials (ERPs) were collected during the encoding phases and the recognition phases from three recognition memory paradigm experiments. In Experiment 1, 22 males who experienced an MTBI 1 month prior, 21 males who experienced an MTBI 24 months prior, and 19 control group males completed two recognition memory tasks, one under deep and one under shallow Level-of-processing conditions, using low frequency nouns as stimuli. ERP data from the deep Level-of-processing encoding phase showed that the expected subsequent memory effect of greater mean amplitude (500-800ms) for subsequently remembered than subsequently missed studied words was present for the control group and the 24 month MTBI group, yet absent for the 1 month MTBI group. Recognition phase data showed that neither MTBI group displayed the implicit memory effect of greater mean amplitude (300-500ms) parietally for missed old words compared to unstudied words under shallow Level-of-processing conditions, whereas the control group did. Experiment 2 employed the same experimental paradigm as Experiment 1 and involved MTBI participants from both MTBI groups from Experiment 1. Fifteen participants from the 1 month MTBI group completed the experimental tasks at approximately 7 month following Experiment 1 (labelled 'Time 2'), and 12 of these participants completed the experimental task a third occasion after a further 10 months (labelled 'Time 3'). Sixteen participants from the 24 month MTBI group completed the same experimental task approximately 13 months after Experiment 1 (labelled 'Time 2'). The results from the encoding phase of Experiment 2 showed that the 1 month MTBI group displayed a subsequent memory effect at Time 2. However, at Time 3 for the 1 month MTBI group and at Time 2 for the 24 month MTBI group, no subsequent memory effects were present due to an apparent increase in mean amplitude elicited by subsequently missed old words. These results suggest that there may be impairment or change in processes involved in encoding meaningful information which, over months and years following the acute post-injury phase, may lead to adaption in these processes. Within recognition phase data results from both MTBI groups showed an…

Subjects/Keywords: Brain; Brain damage; Cognitive psychology

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Little, J. S. (2010). Change in electrophysiological correlates of recognition memory processes following mild traumatic brain injury. (Thesis). University of Tasmania. Retrieved from https://eprints.utas.edu.au/20758/1/whole_LittleJasonStuart2010_thesis.pdf

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Little, Jason Stuart. “Change in electrophysiological correlates of recognition memory processes following mild traumatic brain injury.” 2010. Thesis, University of Tasmania. Accessed February 26, 2021. https://eprints.utas.edu.au/20758/1/whole_LittleJasonStuart2010_thesis.pdf.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Little, Jason Stuart. “Change in electrophysiological correlates of recognition memory processes following mild traumatic brain injury.” 2010. Web. 26 Feb 2021.

Vancouver:

Little JS. Change in electrophysiological correlates of recognition memory processes following mild traumatic brain injury. [Internet] [Thesis]. University of Tasmania; 2010. [cited 2021 Feb 26]. Available from: https://eprints.utas.edu.au/20758/1/whole_LittleJasonStuart2010_thesis.pdf.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Little JS. Change in electrophysiological correlates of recognition memory processes following mild traumatic brain injury. [Thesis]. University of Tasmania; 2010. Available from: https://eprints.utas.edu.au/20758/1/whole_LittleJasonStuart2010_thesis.pdf

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Manchester

22. Sweetmore, George Matthew. PERFORMANCE ANALYSIS AND RADIATION DAMAGE ESTIMATION OF THE STOPPING TARGET MONITOR DETECTORS IN MU2E.

Degree: 2020, University of Manchester

URL: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:323319

► The Mu2e experiment aims to search for the charged lepton flavour violating (CLFV) process of a coherent, neutrinoless, conversion of a muon into an electron… (more)

▼ The Mu2e experiment aims to search for the charged lepton flavour violating (CLFV) process of a coherent, neutrinoless, conversion of a muon into an electron within the proximity of an aluminium nucleus. Mu2e seeks to measure the ratio (R_{μ e}) of the rate of this conversion process, relative to that of ordinary muon capture. Mu2e will achieve world-leading sensitivity, improving the current limit of R_{μ e} < 7 × 10^-13(90%\,{{C.L.}}), set by the SINDRUM-II experiment, by an order of 10⁴. This corresponds to a single-event sensitivity of R_{μ e} < 2.87 × 10^-17(90%\,{C.L.}). Many beyond Standard Model (BSM) theories require CLFV to occur at a rate accessible by Mu2e. Any observation of CLFV at Mu2e would have profound implications on particle physics.\ The Stopping Target Monitor (STM) will be comprised of both a HPGe and a LaBr3 detector which will monitor the signals of photons produced in stopped-muon processes to a required accuracy of 10%. To achieve the desired sensitivity, it is imperative that the detectors perform at their optimal level. The STM detectors are placed within a harsh radiation environment in the form of a high energy `flash' of gamma radiation as well as a flux of fast neutrons.\ Estimations of radiation damage to HPGe in literature is limited. This thesis reports an approach which utilizes the Kinetic-Energy Released in Matter (KERMA) parameter that considers the energy dependence of the incident flux and the cross-section information for the incident particle. Resampling schemes have been adopted to give a realistic rate over the experiment run time. The results have then been normalized to the radiation damage caused by a {}²⁵²Cf source. \ The estimated time before annealing of the detector is necessary is found to be 75 and 78~months in the case of neutron damage and τ ∼ 24~years, 11~months in the case of electron/positron induced damage. This shows significant improvement on the previous estimations. Advisors/Committee Members: Appleby, Robert RB, Gersabeck, Marco, Appleby, Robert.

Subjects/Keywords: Mu2e; Radiation; Neutron damage

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Sweetmore, G. M. (2020). PERFORMANCE ANALYSIS AND RADIATION DAMAGE ESTIMATION OF THE STOPPING TARGET MONITOR DETECTORS IN MU2E. (Doctoral Dissertation). University of Manchester. Retrieved from http://www.manchester.ac.uk/escholar/uk-ac-man-scw:323319

Chicago Manual of Style (16^th Edition):

Sweetmore, George Matthew. “PERFORMANCE ANALYSIS AND RADIATION DAMAGE ESTIMATION OF THE STOPPING TARGET MONITOR DETECTORS IN MU2E.” 2020. Doctoral Dissertation, University of Manchester. Accessed February 26, 2021. http://www.manchester.ac.uk/escholar/uk-ac-man-scw:323319.

MLA Handbook (7^th Edition):

Sweetmore, George Matthew. “PERFORMANCE ANALYSIS AND RADIATION DAMAGE ESTIMATION OF THE STOPPING TARGET MONITOR DETECTORS IN MU2E.” 2020. Web. 26 Feb 2021.

Vancouver:

Sweetmore GM. PERFORMANCE ANALYSIS AND RADIATION DAMAGE ESTIMATION OF THE STOPPING TARGET MONITOR DETECTORS IN MU2E. [Internet] [Doctoral dissertation]. University of Manchester; 2020. [cited 2021 Feb 26]. Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:323319.

Council of Science Editors:

Sweetmore GM. PERFORMANCE ANALYSIS AND RADIATION DAMAGE ESTIMATION OF THE STOPPING TARGET MONITOR DETECTORS IN MU2E. [Doctoral Dissertation]. University of Manchester; 2020. Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:323319

University of Manchester

23. Lai, Ching-Hung. Simulation of 3D Sensors.

Degree: 2013, University of Manchester

URL: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:211707

► The Large Hadron Collider (LHC) at CERN has the highest energy and luminosity in the world. Radiation hardness is then a critical requirement for the… (more)

Subjects/Keywords: 3D silicon sensor; radiation damage

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Lai, C. (2013). Simulation of 3D Sensors. (Doctoral Dissertation). University of Manchester. Retrieved from http://www.manchester.ac.uk/escholar/uk-ac-man-scw:211707

Chicago Manual of Style (16^th Edition):

Lai, Ching-Hung. “Simulation of 3D Sensors.” 2013. Doctoral Dissertation, University of Manchester. Accessed February 26, 2021. http://www.manchester.ac.uk/escholar/uk-ac-man-scw:211707.

MLA Handbook (7^th Edition):

Lai, Ching-Hung. “Simulation of 3D Sensors.” 2013. Web. 26 Feb 2021.

Vancouver:

Lai C. Simulation of 3D Sensors. [Internet] [Doctoral dissertation]. University of Manchester; 2013. [cited 2021 Feb 26]. Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:211707.

Council of Science Editors:

Lai C. Simulation of 3D Sensors. [Doctoral Dissertation]. University of Manchester; 2013. Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:211707

Vanderbilt University

24. Sedgeman, Carl Andrew. Formation, Degradation, and Bypass of DNA-Protein Crosslinks.

Degree: PhD, Biochemistry, 2018, Vanderbilt University

URL: http://hdl.handle.net/1803/14171

► The preservation of DNA replication is requisite for cellular integrity and prevention of tumor formation and cell death. The Y-family DNA polymerases (Pol eta, kappa,… (more)

Subjects/Keywords: carcinogens; enzymology; DNA damage

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Sedgeman, C. A. (2018). Formation, Degradation, and Bypass of DNA-Protein Crosslinks. (Doctoral Dissertation). Vanderbilt University. Retrieved from http://hdl.handle.net/1803/14171

Chicago Manual of Style (16^th Edition):

Sedgeman, Carl Andrew. “Formation, Degradation, and Bypass of DNA-Protein Crosslinks.” 2018. Doctoral Dissertation, Vanderbilt University. Accessed February 26, 2021. http://hdl.handle.net/1803/14171.

MLA Handbook (7^th Edition):

Sedgeman, Carl Andrew. “Formation, Degradation, and Bypass of DNA-Protein Crosslinks.” 2018. Web. 26 Feb 2021.

Vancouver:

Sedgeman CA. Formation, Degradation, and Bypass of DNA-Protein Crosslinks. [Internet] [Doctoral dissertation]. Vanderbilt University; 2018. [cited 2021 Feb 26]. Available from: http://hdl.handle.net/1803/14171.

Council of Science Editors:

Sedgeman CA. Formation, Degradation, and Bypass of DNA-Protein Crosslinks. [Doctoral Dissertation]. Vanderbilt University; 2018. Available from: http://hdl.handle.net/1803/14171

Vanderbilt University

25. Gollub, Sarah Louise. Systematic Investigation of Defect-Mediated Photoluminescence Through Radiation-Induced Displacement Damage.

Degree: PhD, Interdisciplinary Materials Science, 2015, Vanderbilt University

URL: http://hdl.handle.net/1803/11152

► Phosphors have been used for radiation detection before, but only for non-ionizing radiation. In fact, many phosphors are designed to be radiation-resistant so they can… (more)

Subjects/Keywords: lifetime; phosphors; radiation damage; spectroscopy

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Gollub, S. L. (2015). Systematic Investigation of Defect-Mediated Photoluminescence Through Radiation-Induced Displacement Damage. (Doctoral Dissertation). Vanderbilt University. Retrieved from http://hdl.handle.net/1803/11152

Chicago Manual of Style (16^th Edition):

Gollub, Sarah Louise. “Systematic Investigation of Defect-Mediated Photoluminescence Through Radiation-Induced Displacement Damage.” 2015. Doctoral Dissertation, Vanderbilt University. Accessed February 26, 2021. http://hdl.handle.net/1803/11152.

MLA Handbook (7^th Edition):

Gollub, Sarah Louise. “Systematic Investigation of Defect-Mediated Photoluminescence Through Radiation-Induced Displacement Damage.” 2015. Web. 26 Feb 2021.

Vancouver:

Gollub SL. Systematic Investigation of Defect-Mediated Photoluminescence Through Radiation-Induced Displacement Damage. [Internet] [Doctoral dissertation]. Vanderbilt University; 2015. [cited 2021 Feb 26]. Available from: http://hdl.handle.net/1803/11152.

Council of Science Editors:

Gollub SL. Systematic Investigation of Defect-Mediated Photoluminescence Through Radiation-Induced Displacement Damage. [Doctoral Dissertation]. Vanderbilt University; 2015. Available from: http://hdl.handle.net/1803/11152

Anna University

26. Santhi D. Study of anatomical And pathological feature Segmentation in retinal images With diabetic retinopathy;.

Degree: Study of anatomical And pathological feature Segmentation in retinal images With diabetic retinopathy, 2015, Anna University

URL: http://shodhganga.inflibnet.ac.in/handle/10603/39886

►

Human eye is a vital part of the human body Damage to the tiny newlineblood vessels in the retina due to diabetes is named as… (more)

Subjects/Keywords: Diabetic Retinopathy; Human body Damage

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

D, S. (2015). Study of anatomical And pathological feature Segmentation in retinal images With diabetic retinopathy;. (Thesis). Anna University. Retrieved from http://shodhganga.inflibnet.ac.in/handle/10603/39886

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

D, Santhi. “Study of anatomical And pathological feature Segmentation in retinal images With diabetic retinopathy;.” 2015. Thesis, Anna University. Accessed February 26, 2021. http://shodhganga.inflibnet.ac.in/handle/10603/39886.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

D, Santhi. “Study of anatomical And pathological feature Segmentation in retinal images With diabetic retinopathy;.” 2015. Web. 26 Feb 2021.

Vancouver:

D S. Study of anatomical And pathological feature Segmentation in retinal images With diabetic retinopathy;. [Internet] [Thesis]. Anna University; 2015. [cited 2021 Feb 26]. Available from: http://shodhganga.inflibnet.ac.in/handle/10603/39886.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

D S. Study of anatomical And pathological feature Segmentation in retinal images With diabetic retinopathy;. [Thesis]. Anna University; 2015. Available from: http://shodhganga.inflibnet.ac.in/handle/10603/39886

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Texas A&M University

27. Boltz, Kara A. Telomere Regulation in Arabidopsis thaliana by the CST Capping Complex and DNA Damage Response Proteins.

Degree: PhD, Biology, 2013, Texas A&M University

URL: http://hdl.handle.net/1969.1/151678

► The ends of chormosomes are capped by telomeres, which distinguish the termini from damaged DNA. Paradoxically, DNA repair proteins are also required for telomere maintenance.… (more)

▼ The ends of chormosomes are capped by telomeres, which distinguish the termini from damaged DNA. Paradoxically, DNA repair proteins are also required for telomere maintenance. How DNA repair pathways are regulated to maintain telomeres while remaining competent to repair DNA damage throughout the genome is unknown. In this dissertation, I used a genetic approach to investigate how critical components of telomerase and the telomere protein complex interact with the DNA damage response (DDR). In the flowering plant, Arabidopsis thaliana telomeres are bound by the CST (CTC1/STN1/TEN1) heterotrimer. Loss of any CST component results in telomere shortening, telomere fusions, increased G-overhang length and telomere recombination. To understand the phenotypes caused by CST deficiency, I examined telomeres from plants lacking CTC1 or STN1 and TERT or KU. My analysis showed that CST acts in a separate genetic pathway for telomere length regulation from both KU and TERT. Further, I found that KU and CST act in separate genetic pathways for regulation of G-overhang formation. These demonstrate that multiple pathways are used to maintain telomere length and architecture in plants. My study of the interaction of telomere components with the DDR revealed ATR promotes genome stability and telomere length maintenance in the absence of CTC1, probably by activating programmed cell death of stem cells with high amounts of DNA damage. I also found that poly(ADP-ribosylation) is not required for maintenance of Arabidopsis telomeres, in contrast to human telomeres. Finally, I found an unexpected connection between the DDR and telomerase. My research showed that ATR maintains telomerase activity levels. Further, induction of double- stranded DNA breaks in seedlings led to a rapid decrease in telomerase activity, which correlated with increased abundance of TER2, an alternate Arabidopsis telomerase RNA. I hypothesize that TER2 inhibits telomerase to prevent its inappropriate action at internal sites in chromosomes. These data reveal two ways that DDR pathways work in concert with telomerase to promote genome integrity. Advisors/Committee Members: Shippen, Dorothy E (advisor), McKnight, Thomas (advisor), Versaw, Wayne (committee member), Peterson, David O (committee member).

Subjects/Keywords: Telomeres; Telomerase; DNA damage; CST

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Boltz, K. A. (2013). Telomere Regulation in Arabidopsis thaliana by the CST Capping Complex and DNA Damage Response Proteins. (Doctoral Dissertation). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/151678

Chicago Manual of Style (16^th Edition):

Boltz, Kara A. “Telomere Regulation in Arabidopsis thaliana by the CST Capping Complex and DNA Damage Response Proteins.” 2013. Doctoral Dissertation, Texas A&M University. Accessed February 26, 2021. http://hdl.handle.net/1969.1/151678.

MLA Handbook (7^th Edition):

Boltz, Kara A. “Telomere Regulation in Arabidopsis thaliana by the CST Capping Complex and DNA Damage Response Proteins.” 2013. Web. 26 Feb 2021.

Vancouver:

Boltz KA. Telomere Regulation in Arabidopsis thaliana by the CST Capping Complex and DNA Damage Response Proteins. [Internet] [Doctoral dissertation]. Texas A&M University; 2013. [cited 2021 Feb 26]. Available from: http://hdl.handle.net/1969.1/151678.

Council of Science Editors:

Boltz KA. Telomere Regulation in Arabidopsis thaliana by the CST Capping Complex and DNA Damage Response Proteins. [Doctoral Dissertation]. Texas A&M University; 2013. Available from: http://hdl.handle.net/1969.1/151678

Texas A&M University

28. Jahangir, Rezwan. The Examination of Asphalt Binder Microrheology Using Atomic Force Microscopy and the Finite Element Method.

Degree: PhD, Civil Engineering, 2015, Texas A&M University

URL: http://hdl.handle.net/1969.1/187011

► In order to obtain a better understanding the complex mechanical behavior of asphalt binder, its microstructure must be examined. In addition, the interrelationship between asphalt… (more)

▼ In order to obtain a better understanding the complex mechanical behavior of asphalt binder, its microstructure must be examined. In addition, the interrelationship between asphalt binder microstructure, damage, and mechanical properties must also be determined. In this work the unique relationship between asphalt binder microstructure and damaging mechanisms is established. Here, the AFM is used to image the microstructure of two different types of asphalt binders. A micrometer driven mechanical device named a "Micro-Loading Frame" is used to obtain AFM images of bitumen surface after subjecting it to high levels of tensile strain. Using image analysis techniques the microstructural changes due to the applied tensile strain is established. Furthermore, using a specific AFM creep indentation protocol the viscoelastic properties of asphalt binder are extracted for each microstructural phase observed. In addition, this concept was applied to rolling thin film oven test (RTFOT) aged and pressure aging vessel (PAV) aged binders. The geometry obtained from AFM imaging combined with the microrheology obtained from AFM creep indentation experiments were used to construct finite element simulations examining local stress distributions. The numerical solutions were compared to experimental observations. Using AFM imaging technique three unique phases were found within the asphalt binder at the micron length scale i.e. bee, bee casing, and interstitial. All three phases were found to have uniquely different viscoelastic properties. Finite element analysis results showed that heterogeneity within the asphalt binder led to localized stress amplification. Application of high levels of tensile loads resulted in phase separation and cracking referred to as load induced phase separation (LIPS) zones. The occurrence of the LIPS zones were primarily found to be within interstitial regions. Application of tensile strains also resulted in the reduction of the number of bee structures, and also the area occupied by the bee structures. The location of LIPS zones coincided with the location high stress zones determined using the finite element simulations suggesting the possibility of phase separation and cracking occurring due to localized high stresses. Application of tensile strains to RTFOT, and RTFOT+PAV aged samples also resulted in the formation of LIPS zones within the interstitial regions. However, an increase in the level of aging the led to a reduction of LIPS zone formations for the same level of applied tensile displacements. The effect of geometry of asphalt binder microstructure on the mechanical response was determined. An increase in the area fraction of the bee/bee casing phase, a reduction in the distance between adjacent bee/bee casing features led to an increase in the maximum stress magnitudes. An increase in the number of bee/bee casing features led to a reduction in the maximum stress magnitude when the area fraction was kept constant. Advisors/Committee Members: Little, Dallas (advisor), Glover, Charles (committee member), Grasley, Zachary (committee member), Bhasin, Amit (committee member), Lytton, Robert (committee member).

Subjects/Keywords: AFM; Asphalt Binder; Damage; Microrheology

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Jahangir, R. (2015). The Examination of Asphalt Binder Microrheology Using Atomic Force Microscopy and the Finite Element Method. (Doctoral Dissertation). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/187011

Chicago Manual of Style (16^th Edition):

Jahangir, Rezwan. “The Examination of Asphalt Binder Microrheology Using Atomic Force Microscopy and the Finite Element Method.” 2015. Doctoral Dissertation, Texas A&M University. Accessed February 26, 2021. http://hdl.handle.net/1969.1/187011.

MLA Handbook (7^th Edition):

Jahangir, Rezwan. “The Examination of Asphalt Binder Microrheology Using Atomic Force Microscopy and the Finite Element Method.” 2015. Web. 26 Feb 2021.

Vancouver:

Jahangir R. The Examination of Asphalt Binder Microrheology Using Atomic Force Microscopy and the Finite Element Method. [Internet] [Doctoral dissertation]. Texas A&M University; 2015. [cited 2021 Feb 26]. Available from: http://hdl.handle.net/1969.1/187011.

Council of Science Editors:

Jahangir R. The Examination of Asphalt Binder Microrheology Using Atomic Force Microscopy and the Finite Element Method. [Doctoral Dissertation]. Texas A&M University; 2015. Available from: http://hdl.handle.net/1969.1/187011

Texas A&M University

29. Evans, Jordan Andrew. Anisotropic Response of Laser Additively Manufactured Nuclear Alloys to Radiation Damage.

Degree: PhD, Materials Science and Engineering, 2017, Texas A&M University

URL: http://hdl.handle.net/1969.1/169649

► The impact of radiation-induced effects on the properties of alloys fabricated using additive manufacturing (AM) was evaluated through the implementation of ion beam irradiation testing… (more)

▼ The impact of radiation-induced effects on the properties of alloys fabricated using additive manufacturing (AM) was evaluated through the implementation of ion beam irradiation testing followed by electron backscatter diffraction (EBSD), scanning electron microscopy (SEM) with energy dispersive spectroscopy (EDS), nanoindentation, scanning probe microscopy (SPM), and transmission electron microscopy (TEM). Inconel 600 (I600) and 316L stainless steel (316L) rods were fabricated by Quad City Manufacturing Laboratory in collaboration with Lockheed Martin for this study. The rods were produced in three distinct orientations (vertical, horizontal, and 45°) using laser additive manufacturing (LAM). Conventionally manufactured I600 and 316L rods were purchased from Metal Samples, Inc. to enable comparative studies. The I600 and 316L LAM specimens were heat treated to 900 °C and 650 °C in argon with no cold working, respectively. Similarly, the conventionally manufactured I600 and 316L control specimens were cold rolled and annealed at 980 °C and 1040 °C in argon with no cold working, respectively. XRD of unirradiated specimens showed differences in peak ratios between build orientations, indicating anisotropic grain structures for samples fabricated by LAM. All LAM rods contained significantly fewer coincidence site lattice (CSL) boundaries and more residual strain compared to the controls before and after irradiation, regardless of build direction, as determined by EBSD. Material performance parameters such as resistance to radiation-enhanced embrittlement, corrosion, creep, intergranular stress corrosion cracking, and hydrogen-induced cracking were inferred from CSL theory, which suggests that all LAM rods are more susceptible to grain boundary-related failure mechanisms than their conventionally manufactured counterparts. All alloys built by LAM are strongly textured with parallel to the build direction before and after irradiation. Directionally dependent Taylor Factor distributions suggest that resistance to slip depends on build direction where, from highest to lowest resistance: horizontal > 45° > vertical. All I600 samples experienced radiation-induced segregation which, according to SEM/EDS and SPM studies, resulted in the formation of chromium carbide precipitates on to the irradiated surfaces. Strong anisotropic mechanical behavior was observed in the LAM rods, as measured by nanoindentation and bulk tensile testing. The hardness of the unirradiated as-annealed specimens, from greatest to least, is: horizontal > 45° > vertical. The radiation-induced hardening of LAM specimens, from greatest to least, is: horizontal > 45° > vertical. The orientation dependence of radiation-induced segregation and hardening mechanisms is discussed. The ultimate outcome of this work is a first-of-a-kind high-dose radiation damage study of alloys fabricated by LAM, revealing that the radiation-induced changes in material properties for these alloys is dependent upon build orientation. Advisors/Committee Members: McDeavitt, Sean (advisor), Perez-Nunez, Delia (committee member), Shao, Lin (committee member), Shamberger, Patrick (committee member), Tsvetkov, Pavel (committee member).

Subjects/Keywords: additive manufacturing; radiation damage; anisotropy

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Evans, J. A. (2017). Anisotropic Response of Laser Additively Manufactured Nuclear Alloys to Radiation Damage. (Doctoral Dissertation). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/169649

Chicago Manual of Style (16^th Edition):

Evans, Jordan Andrew. “Anisotropic Response of Laser Additively Manufactured Nuclear Alloys to Radiation Damage.” 2017. Doctoral Dissertation, Texas A&M University. Accessed February 26, 2021. http://hdl.handle.net/1969.1/169649.

MLA Handbook (7^th Edition):

Evans, Jordan Andrew. “Anisotropic Response of Laser Additively Manufactured Nuclear Alloys to Radiation Damage.” 2017. Web. 26 Feb 2021.

Vancouver:

Evans JA. Anisotropic Response of Laser Additively Manufactured Nuclear Alloys to Radiation Damage. [Internet] [Doctoral dissertation]. Texas A&M University; 2017. [cited 2021 Feb 26]. Available from: http://hdl.handle.net/1969.1/169649.

Council of Science Editors:

Evans JA. Anisotropic Response of Laser Additively Manufactured Nuclear Alloys to Radiation Damage. [Doctoral Dissertation]. Texas A&M University; 2017. Available from: http://hdl.handle.net/1969.1/169649

Texas A&M University

30. Caro Spinel, Silvia. A Coupled Micromechanical Model of Moisture-Induced Damage in Asphalt Mixtures: Formulation and Applications.

Degree: PhD, Civil Engineering, 2011, Texas A&M University

URL: http://hdl.handle.net/1969.1/ETD-TAMU-2009-12-7336

► The deleterious effect of moisture on the structural integrity of asphalt mixtures has been recognized as one of the main causes of early deterioration of… (more)

▼ The deleterious effect of moisture on the structural integrity of asphalt mixtures has been recognized as one of the main causes of early deterioration of asphalt pavements. This phenomenon, usually referred to as moisture damage, is defined as the progressive loss of structural integrity of the mixture that is primarily caused by the presence of moisture in liquid or vapor state. Moisture damage is associated with the development of different physical, mechanical, and chemical processes occurring within the microstructure of the mixture at different intensities and rates. Although there have been important advancements in identifying and characterizing this phenomenon, there is still a lack of understanding of the damage mechanisms occurring at the microscopic level. This situation has motivated the research work reported in this dissertation. The main objective of this dissertation is to formulate and apply a numerical micromechanical model of moisture-induced damage in asphalt mixtures. The model focuses on coupling the effects of moisture diffusion—one of the three main modes of moisture transport within asphalt mixtures—with the mechanical performance of the microstructure. Specifically, the model aims to account for the effect of moisture diffusion on the degradation of the viscoelastic bulk matrix of the mixture (i.e., cohesive degradation) and on the gradual deterioration of the adhesive bonds between the aggregates and the asphalt matrix (i.e., adhesive degradation). The micromechanical model was applied to study the role of some physical and mechanical properties of the constitutive phases of the mixtures on the susceptibility of the mixture to moisture damage. The results from this analysis suggest that the diffusion coefficients of the asphalt matrix and aggregates, as well as the bond strength of the aggregate-matrix interface, have the most influence on the moisture susceptibility of the mixtures. The micromechanical model was further used to investigate the influence of the void phase of asphalt mixtures on the generation of moisture-related deterioration processes. Two different probabilistic-based approaches were used to accomplish this objective. In the first approach, a volumetric distribution of air voids sizes measured using X-Ray Computed Tomography in a dense-graded asphalt mixture was used to generate probable void structures in a microstructure of an asphalt mixture. In the second approach, a stochastic modeling technique based on random field theory was used to generate probable air voids distributions of the mixture. In this second approach, the influence of the air voids was accounted for by making the physical and mechanical properties of the asphalt matrix dependent on probable voids distributions. Although both approaches take into consideration the characteristics of the air void phase on the mechanical response of the mixtures subjected to moist environments, the former explicitly introduces the air phase within the microstructure while the latter indirectly includes its effects… Advisors/Committee Members: Masad, Eyad (advisor), Chen, Hamn-Ching (committee member), Little, Dallas (committee member), Lytton, Robert (committee member), Muliana, Anastasia (committee member), Scarpas, Athanasios (committee member).

Subjects/Keywords: Moisture damage; asphalt mixtures; micromechanics

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Caro Spinel, S. (2011). A Coupled Micromechanical Model of Moisture-Induced Damage in Asphalt Mixtures: Formulation and Applications. (Doctoral Dissertation). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/ETD-TAMU-2009-12-7336

Chicago Manual of Style (16^th Edition):

Caro Spinel, Silvia. “A Coupled Micromechanical Model of Moisture-Induced Damage in Asphalt Mixtures: Formulation and Applications.” 2011. Doctoral Dissertation, Texas A&M University. Accessed February 26, 2021. http://hdl.handle.net/1969.1/ETD-TAMU-2009-12-7336.

MLA Handbook (7^th Edition):

Caro Spinel, Silvia. “A Coupled Micromechanical Model of Moisture-Induced Damage in Asphalt Mixtures: Formulation and Applications.” 2011. Web. 26 Feb 2021.

Vancouver:

Caro Spinel S. A Coupled Micromechanical Model of Moisture-Induced Damage in Asphalt Mixtures: Formulation and Applications. [Internet] [Doctoral dissertation]. Texas A&M University; 2011. [cited 2021 Feb 26]. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2009-12-7336.

Council of Science Editors:

Caro Spinel S. A Coupled Micromechanical Model of Moisture-Induced Damage in Asphalt Mixtures: Formulation and Applications. [Doctoral Dissertation]. Texas A&M University; 2011. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2009-12-7336

Open Access Theses and Dissertations