You searched for subject:(crossover).
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1.
Salkind, Micah Eli.
“Do You Remember House?” Memory, Mediation, and Crossover
Community-Making in Chicago House Music Culture.
Degree: PhD, American Studies, 2016, Brown University
URL: https://repository.library.brown.edu/studio/item/bdr:674250/ 
► This thesis is an interdisciplinary study of house music, the rhythmically-focused electronic dance sound born in the post-industrial “maroon” spaces of Chicago’s queer, black, and…
(more)
▼ This thesis is an interdisciplinary study of house
music, the rhythmically-focused electronic dance sound born in the
post-industrial “maroon” spaces of Chicago’s queer, black, and
Latino social dancers. Working from oral history interviews,
archival research, and performance ethnography, it argues that the
“queer remediation” and adaptation of house music by multiple and
overlapping “
crossover communities” in its first decade shaped the
ways that contemporary Chicago house music producers, DJs, dancers,
and promoters invoke and memorialize house as an archive indexing
experiences of pansexual, multiracial, and trans-generational
congregation. The project’s analytic engagement with musical,
kinesthetic, visual, and other materials pertaining to house music
culture builds from a tradition of queer of color critique that
resists progressive narratives of cultural development and fixity.
It considers house music’s liberatory potential to be intrinsic to
its status as a flexible “repertoire in motion” as opposed to a
fixed canon. This project engages with and extends the fields of
African American studies, urban studies, gender and sexuality
studies, dance studies, performance studies, popular music studies,
ethnomusicology, and media studies.
Advisors/Committee Members: Rose, Tricia (Director), Miller, Kiri (Reader), Gutterl, Matthew (Reader).
Subjects/Keywords: crossover communities
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APA (6th Edition):
Salkind, M. E. (2016). “Do You Remember House?” Memory, Mediation, and Crossover
Community-Making in Chicago House Music Culture. (Doctoral Dissertation). Brown University. Retrieved from https://repository.library.brown.edu/studio/item/bdr:674250/
Chicago Manual of Style (16th Edition):
Salkind, Micah Eli. ““Do You Remember House?” Memory, Mediation, and Crossover
Community-Making in Chicago House Music Culture.” 2016. Doctoral Dissertation, Brown University. Accessed March 01, 2021.
https://repository.library.brown.edu/studio/item/bdr:674250/.
MLA Handbook (7th Edition):
Salkind, Micah Eli. ““Do You Remember House?” Memory, Mediation, and Crossover
Community-Making in Chicago House Music Culture.” 2016. Web. 01 Mar 2021.
Vancouver:
Salkind ME. “Do You Remember House?” Memory, Mediation, and Crossover
Community-Making in Chicago House Music Culture. [Internet] [Doctoral dissertation]. Brown University; 2016. [cited 2021 Mar 01].
Available from: https://repository.library.brown.edu/studio/item/bdr:674250/.
Council of Science Editors:
Salkind ME. “Do You Remember House?” Memory, Mediation, and Crossover
Community-Making in Chicago House Music Culture. [Doctoral Dissertation]. Brown University; 2016. Available from: https://repository.library.brown.edu/studio/item/bdr:674250/
2.
Fernandes, Joiselle Blanche.
Identification et caractérisation fonctionnelle de gènes contrôlant la fréquence de crossovers méiotiques. : Identification and Functional Characterization of Genes Involved in the Control of Meiotic Crossover Frequency.
Degree: Docteur es, Biologie, 2017, Université Paris-Saclay (ComUE)
URL: http://www.theses.fr/2017SACLS303
► Les crossing-overs (CO) sont issus d’échange réciproque de matériel génétique entre les chromosomes homologues. Les COs produisent de la diversité génétique et sont essentiels chez…
(more)
▼ Les crossing-overs (CO) sont issus d’échange réciproque de matériel génétique entre les chromosomes homologues. Les COs produisent de la diversité génétique et sont essentiels chez la plupart des eucaryotes, pour la distribution équilibrée des chromosomes lors de la méiose. Malgré leur importance, et un large excès de précurseurs moléculaires, le nombre de CO est très limité dans la grande majorité des espèces (Typiquement 1 à 4 par paire de chromosomes). Cela suggère que les COs sont étroitement régulés, mais les mécanismes sous-jacents sont mal connus. Pour identifier les gènes qui limitent la formation des CO, l’équipe a mené un crible génétique chez Arabidopsis thaliana. Ces travaux ont mené à l’identification de plusieurs facteurs anti-CO, définissant trois voies : (i) L’hélicase FANCM et ses co-facteurs ; (ii) L’AAA-ATPase FIDGETIN-LIKE-1 (FIGL1) ; (iii) Le complexe RECQ4-Topoisomerase 3α-RMI1.Le premier objectif de ma thèse est d’explorer les relations entre ces trois voies en s’attachant aux questions suivantes ; (1) Jusqu’où peut-on augmenter la recombinaison en combinant les mutations dans FANCM, FIGL1 et RECQ4 ? Nous avons montré que la plus forte augmentation de recombinaison était obtenue dans recq4 figl1, atteignant 7,5 fois la fréquence du sauvage en moyenne sur le génome. (2) Quel est la distribution de ces extra-COs ? L’augmentation de recombinaison n’est pas homogène le long du génome : Les fréquences de CO augmente fortement des centromères vers les télomères, avec les plus hautes fréquences observées dans les régions distales. (3) La modification des fréquences de recombinaison est-elle identique lors des méioses mâles et femelle ? Chez le sauvage, la fréquence de recombinaison est plus élevée lors de la méiose mâle que femelle. Au contraire, la recombinaison femelle devient plus élevée que la recombinaison mâle chez les mutants recq4 et recq4 figl1. Ceci suggère que des contraintes qui s’appliquent sur la formation des CO lors de la méiose femelle sont relâchées chez ces mutants. En poursuivant le crible génétique, un nouveau mutant hyper-recombinant a été identifié. Le second objectif de ma thèse fut d’identifier et de caractériser fonctionnellement le gène correspondant. Une cartographie génétique et des études d’interactions protéine-protéine, ont mené à l’identification d’un facteur qui interagit directement avec FIGL1 et semble former un complexe conservé depuis les plantes jusqu’au mammifères. Nous avons baptisé cette protéine FLIP (Fidgetin-like-1 interacting protein). Les fréquences de recombinaisons sont augmentées dans flip-1, confirmant que FLIP1 limite la formation des COs. Des études d’épistasie ont montré que FLIP et FIGL1 agissent dans la même voie. De plus les protéines FIGL1/FLIP d’Arabidopsis ou humaine, interagissent avec RAD51 et DMC1, les deux protéines qui catalyse une étape clef de la recombinaison, l’invasion d’un ADN homologue. Finalement, dans flip comme dans figl1, la dynamique de DMC1 est modifiée. Nous proposons donc un modèle dans lequel le complexe FLIP-FIGL1 régule…
Advisors/Committee Members: Mercier, Raphaël (thesis director).
Subjects/Keywords: Meiose; Crossover; Recombination; Meiosis; Crossover; Recombination
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APA (6th Edition):
Fernandes, J. B. (2017). Identification et caractérisation fonctionnelle de gènes contrôlant la fréquence de crossovers méiotiques. : Identification and Functional Characterization of Genes Involved in the Control of Meiotic Crossover Frequency. (Doctoral Dissertation). Université Paris-Saclay (ComUE). Retrieved from http://www.theses.fr/2017SACLS303
Chicago Manual of Style (16th Edition):
Fernandes, Joiselle Blanche. “Identification et caractérisation fonctionnelle de gènes contrôlant la fréquence de crossovers méiotiques. : Identification and Functional Characterization of Genes Involved in the Control of Meiotic Crossover Frequency.” 2017. Doctoral Dissertation, Université Paris-Saclay (ComUE). Accessed March 01, 2021.
http://www.theses.fr/2017SACLS303.
MLA Handbook (7th Edition):
Fernandes, Joiselle Blanche. “Identification et caractérisation fonctionnelle de gènes contrôlant la fréquence de crossovers méiotiques. : Identification and Functional Characterization of Genes Involved in the Control of Meiotic Crossover Frequency.” 2017. Web. 01 Mar 2021.
Vancouver:
Fernandes JB. Identification et caractérisation fonctionnelle de gènes contrôlant la fréquence de crossovers méiotiques. : Identification and Functional Characterization of Genes Involved in the Control of Meiotic Crossover Frequency. [Internet] [Doctoral dissertation]. Université Paris-Saclay (ComUE); 2017. [cited 2021 Mar 01].
Available from: http://www.theses.fr/2017SACLS303.
Council of Science Editors:
Fernandes JB. Identification et caractérisation fonctionnelle de gènes contrôlant la fréquence de crossovers méiotiques. : Identification and Functional Characterization of Genes Involved in the Control of Meiotic Crossover Frequency. [Doctoral Dissertation]. Université Paris-Saclay (ComUE); 2017. Available from: http://www.theses.fr/2017SACLS303
Universiteit Utrecht
3.
Ziel, Marie-Elise van der.
The Acquisition of the Weak Crossover Constraint : Evidence from Dutch Preschool Children.
Degree: 2008, Universiteit Utrecht
URL: http://dspace.library.uu.nl:8080/handle/1874/29527
► The Weak Crossover Constraint restricts variable binding in sentences such as (1), in which an operator appears to move past a coindexed embedded pronoun (either…
(more)
▼ The Weak
Crossover Constraint restricts variable binding in sentences such as (1), in which an operator appears to move past a coindexed embedded pronoun (either overtly, or at LF). The pronouns in (1) can thus only be interpreted as deictic pronouns, referring to some previously specified individual in discourse.
(1) a. Hisi mother likes each boyi.
b. Whoi does hisi mother like ti?
In the theoretical literature there has been much debate about the nature of the WCO-constraint. Some researchers have reduced it to restrictions on binding relations (e.g. Koopman and Sportiche 1982, Safir 1984, 2004, and Reinhart 1983). Others have reduced it to scope (e.g. Pica and Snyder 1995, Ruys 2000), prominence (Bresnan 1995, 1998), or have attempted to derive the constraint compositionally in different semantic frameworks (Büring 2004, Schlenker 2005). However, each approach has its own advantages and drawbacks.
Acquisition research can help decide between competing accounts by testing specific predictions about L1-acquisition derived from these theories. However, previous L1-acquisition research has provided a conflicting picture (Thornton 1990, Lewis 2000), which may in part be due to methodological problems.
This thesis reports two experiments which investigate the acquisition of the WCO constraint by Dutch preschoolers. The first experiment tests whether a methodological modification to improve the pragmatic felicity of the pronoun in the test statement improves children’s performance on WCO sentences (as compared to Lewis 2000). Furthermore, it tests a prediction of one of the scope based approaches to WCO (Ruys 2000), namely that children should reject the variable-bound interpretations of WCO sentences, while they should accept variable binding in sentences where a quantifier is seen to exceptionally scope over the sentence The results indicate that 61.9 percent of the children appear to have acquired the WCO constraint. This constitutes a significant improvement over Lewis (2000). In other words, improving the felicity of the test statement indeed improves children’s performance. Furthermore, the results provided evidence in favour of scope-based approaches to WCO.
A second experiment tests the effects of two possibly confounding factors, namely the quantifier children are presented with, and the relative order between the pronoun and the quantifier. In this experiment the results of the first experiment were replicated under a different design. Furthermore, there is no effect of quantifier, but children are affected by the precedence relations obtaining between the pronoun and the quantifier. However, they do not differ from adults in this respect.
Advisors/Committee Members: Philip, William.
Subjects/Keywords: Letteren; acquisition; semantics; Weak Crossover
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APA ·
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APA (6th Edition):
Ziel, M. v. d. (2008). The Acquisition of the Weak Crossover Constraint : Evidence from Dutch Preschool Children. (Masters Thesis). Universiteit Utrecht. Retrieved from http://dspace.library.uu.nl:8080/handle/1874/29527
Chicago Manual of Style (16th Edition):
Ziel, Marie-Elise van der. “The Acquisition of the Weak Crossover Constraint : Evidence from Dutch Preschool Children.” 2008. Masters Thesis, Universiteit Utrecht. Accessed March 01, 2021.
http://dspace.library.uu.nl:8080/handle/1874/29527.
MLA Handbook (7th Edition):
Ziel, Marie-Elise van der. “The Acquisition of the Weak Crossover Constraint : Evidence from Dutch Preschool Children.” 2008. Web. 01 Mar 2021.
Vancouver:
Ziel Mvd. The Acquisition of the Weak Crossover Constraint : Evidence from Dutch Preschool Children. [Internet] [Masters thesis]. Universiteit Utrecht; 2008. [cited 2021 Mar 01].
Available from: http://dspace.library.uu.nl:8080/handle/1874/29527.
Council of Science Editors:
Ziel Mvd. The Acquisition of the Weak Crossover Constraint : Evidence from Dutch Preschool Children. [Masters Thesis]. Universiteit Utrecht; 2008. Available from: http://dspace.library.uu.nl:8080/handle/1874/29527
University of Adelaide
4.
Perry, Kezia.
Shadow of The Archers and Crossing Over: Writing Young Adult Fiction and Finding the Contemporary Reader.
Degree: 2018, University of Adelaide
URL: http://hdl.handle.net/2440/120410
► The notion that crossover fiction has changed the way books are written and the way we read has been addressed in studies increasingly since 1997,…
(more)
▼ The notion that
crossover fiction has changed the way books are written and the way we read has been addressed in studies increasingly since 1997, the year when the first Harry Potter novel was published. Attention and credit has been paid to the Harry Potter series as the genesis of
crossover books while questioning the emergence of a standalone genre separate to young adult fiction. As a young adult writer, I am most interested in this form and whether young adult novels have been eclipsed and impacted by this changing structure and whether the reader has also changed. Young adult fiction has been a wide and fluid category since it was first identified in 1802 by critic Sarah Trimmer who wrote of a young adult age between the ages of fourteen and twenty-one. Young adult fiction has been read and enjoyed widely since the early Nineteenth century but has not enjoyed favourable reviews from critics. However, young adult fiction and
crossover novels alike have found a place in this period of digital and social change and found a large and enthusiastic contemporary readership. In this exegesis I attempt to address the debate about what a
crossover novel is and how it differentiates from young adult fiction by asking the following questions: Has this genre emerged because of certain texts and influences? What separates this genre from young adult fiction? What purpose do
crossover novels have in the current publishing and writing climate? And, how did researching and investigating
crossover novels affect my own young adult writing? When I started writing my creative novel, I had one goal in mind: to create an entertaining and engrossing story. As the project grew in length and eight years passed, the work reflected this aging process. I became less sure of my original goals and determinations in the understanding of the
crossover novel as the landscape had changed from 2011 to 2018. There had begun a downturn in
crossover publishing and a return to purer young adult fiction. I began to examine my own changing and evolving relationship to young adult fiction. My story was not a
crossover novel. It had each of the constructs I had identified as being necessary to the genre of
crossover fiction but
crossover fiction is unable to be determined by the page but by its readership. The story in Shadow of the Archers began as a spy novel for young adults. The story was written to explore the constructs I had valued in books I read growing up. Near the end of this project, I was satisfied I had written a young adult book and not achieved the interconnection of a
crossover novel, as this could not be determined before the book was published and in the hands of readers. It is readers that cross read as books cannot embody a set of constructs to appeal to a wide, cross generational audience nor influenced by publishing and marketing. There have been emergent problems in books attempting to be
crossover books: writers attempting to write
crossover books. I have investigated the complex aspects of the nexus between young adult fiction…
Advisors/Committee Members: Prosser, Rosslyn (advisor), School of Humanities : English and Creative Writing (school).
Subjects/Keywords: Young adult fiction; crossover fiction
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APA (6th Edition):
Perry, K. (2018). Shadow of The Archers and Crossing Over: Writing Young Adult Fiction and Finding the Contemporary Reader. (Thesis). University of Adelaide. Retrieved from http://hdl.handle.net/2440/120410
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Perry, Kezia. “Shadow of The Archers and Crossing Over: Writing Young Adult Fiction and Finding the Contemporary Reader.” 2018. Thesis, University of Adelaide. Accessed March 01, 2021.
http://hdl.handle.net/2440/120410.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Perry, Kezia. “Shadow of The Archers and Crossing Over: Writing Young Adult Fiction and Finding the Contemporary Reader.” 2018. Web. 01 Mar 2021.
Vancouver:
Perry K. Shadow of The Archers and Crossing Over: Writing Young Adult Fiction and Finding the Contemporary Reader. [Internet] [Thesis]. University of Adelaide; 2018. [cited 2021 Mar 01].
Available from: http://hdl.handle.net/2440/120410.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Perry K. Shadow of The Archers and Crossing Over: Writing Young Adult Fiction and Finding the Contemporary Reader. [Thesis]. University of Adelaide; 2018. Available from: http://hdl.handle.net/2440/120410
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
5.
Meitzner, Magdalena.
Gränsryttaren/zaunreiten : ett projekt för dans och slagverk.
Degree: Classical Music, 2011, Royal College of Music in Stockholm
URL: http://urn.kb.se/resolve?urn=urn:nbn:se:kmh:diva-96
Bilagor: 1 programblad, 1 DVD. Medverkande: Magdalena Meitzner - slagverk; Amelia Mauderli - dans, tal
Subjects/Keywords: dans; slagverk; scenisk musik; crossover
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APA (6th Edition):
Meitzner, M. (2011). Gränsryttaren/zaunreiten : ett projekt för dans och slagverk. (Thesis). Royal College of Music in Stockholm. Retrieved from http://urn.kb.se/resolve?urn=urn:nbn:se:kmh:diva-96
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Meitzner, Magdalena. “Gränsryttaren/zaunreiten : ett projekt för dans och slagverk.” 2011. Thesis, Royal College of Music in Stockholm. Accessed March 01, 2021.
http://urn.kb.se/resolve?urn=urn:nbn:se:kmh:diva-96.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Meitzner, Magdalena. “Gränsryttaren/zaunreiten : ett projekt för dans och slagverk.” 2011. Web. 01 Mar 2021.
Vancouver:
Meitzner M. Gränsryttaren/zaunreiten : ett projekt för dans och slagverk. [Internet] [Thesis]. Royal College of Music in Stockholm; 2011. [cited 2021 Mar 01].
Available from: http://urn.kb.se/resolve?urn=urn:nbn:se:kmh:diva-96.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Meitzner M. Gränsryttaren/zaunreiten : ett projekt för dans och slagverk. [Thesis]. Royal College of Music in Stockholm; 2011. Available from: http://urn.kb.se/resolve?urn=urn:nbn:se:kmh:diva-96
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Queens University
6.
Guo, Huan.
Novel Iron(II) Triazole-Pyridine Based Dinuclear Complexes: Synthesis, Characterization And Magnetic Properties
.
Degree: Chemistry, 2013, Queens University
URL: http://hdl.handle.net/1974/8302
► The major focus of this thesis involves a new approach to spin-crossover (SCO) in iron(II) dinuclear complexes. In order to acquire SCO properties, a series…
(more)
▼ The major focus of this thesis involves a new approach to spin-crossover (SCO) in iron(II) dinuclear complexes. In order to acquire SCO properties, a series of novel ligands (L1M, L2M, L3M, L4M), together with the corresponding iron(II) and/or nickel(II) complexes were synthesized and characterized. Beyond the successful synthesis and characterization of these ligands, some interesting aspects of their synthesis are discussed. The reported ligands are methyl-derivatives from ligands previously studied in the group. The methyl group in the position 6 of the pyridine group is introduced to induce steric hindrance in the complexes and decrease the ligand field strength. As a result, the influence of the methyl group may induce SCO in low spin (LS) complexes, or tune the SCO properties (such as transition hysteresis or transition temperature) in complexes with SCO. Ligands were divided into three different types according to their spacers: a ligand with an aromatic spacer (L1M), ligands with aliphatic spacer (L2M, L3M) and a ligand with no spacer (L4M). The difference between their structures helped us to better understand the coordination chemistry of the corresponding complexes. The nickel(II) complexes formed provided useful background information on the coordination chemistry of iron(II), such as the crystal field stabilization energy (10Dq) value. An approximation of 10Dq value of iron(II) was calculated based on the 10Dq value of analogous nickel(II) complexes using an empirical rule, to provide a prediction of SCO property.
Subjects/Keywords: Coordination chemistry
;
Spin Crossover
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APA (6th Edition):
Guo, H. (2013). Novel Iron(II) Triazole-Pyridine Based Dinuclear Complexes: Synthesis, Characterization And Magnetic Properties
. (Thesis). Queens University. Retrieved from http://hdl.handle.net/1974/8302
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Guo, Huan. “Novel Iron(II) Triazole-Pyridine Based Dinuclear Complexes: Synthesis, Characterization And Magnetic Properties
.” 2013. Thesis, Queens University. Accessed March 01, 2021.
http://hdl.handle.net/1974/8302.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Guo, Huan. “Novel Iron(II) Triazole-Pyridine Based Dinuclear Complexes: Synthesis, Characterization And Magnetic Properties
.” 2013. Web. 01 Mar 2021.
Vancouver:
Guo H. Novel Iron(II) Triazole-Pyridine Based Dinuclear Complexes: Synthesis, Characterization And Magnetic Properties
. [Internet] [Thesis]. Queens University; 2013. [cited 2021 Mar 01].
Available from: http://hdl.handle.net/1974/8302.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Guo H. Novel Iron(II) Triazole-Pyridine Based Dinuclear Complexes: Synthesis, Characterization And Magnetic Properties
. [Thesis]. Queens University; 2013. Available from: http://hdl.handle.net/1974/8302
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Louisiana State University
7.
Whipp, Michelle D.
Identification of blood protein in Louisiana clay sediment: subtitle.
Degree: MA, Social and Behavioral Sciences, 2011, Louisiana State University
URL: etd-04132012-173812
;
https://digitalcommons.lsu.edu/gradschool_theses/2582
► In modern forensics, soil from crime scenes is not tested for the presence of blood proteins. This is due to the belief that proteins degrade…
(more)
▼ In modern forensics, soil from crime scenes is not tested for the presence of blood proteins. This is due to the belief that proteins degrade too quickly for detection. The purpose of this paper is to report on the research performed in an effort to counter that belief and in so doing, suggests changes in the current procedures. Using pig blood as an analog for human blood, blood was deposited outside, at two separate locations roughly a half mile apart, at a southern Louisiana cattle farm. Over 18 months, samples were taken from cores at the deposition sites and these were tested for the presence of blood proteins at PaleoResearch Institute in Golden, Colorado. Crossover-Immunoelectrophoresis (CIEP) was used to test over 130 soil samples taken at three-month intervals. Results indicate further research is warranted. The control samples tested negative, while intermittent weak positive results for blood proteins from the samples were obtained. The lack of interpretable patterning in the positive results, however, renders my results inconclusive. Further testing with more controlled variables is required.
Subjects/Keywords: crossover immunoelectrophoresis; blood protein
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APA (6th Edition):
Whipp, M. D. (2011). Identification of blood protein in Louisiana clay sediment: subtitle. (Masters Thesis). Louisiana State University. Retrieved from etd-04132012-173812 ; https://digitalcommons.lsu.edu/gradschool_theses/2582
Chicago Manual of Style (16th Edition):
Whipp, Michelle D. “Identification of blood protein in Louisiana clay sediment: subtitle.” 2011. Masters Thesis, Louisiana State University. Accessed March 01, 2021.
etd-04132012-173812 ; https://digitalcommons.lsu.edu/gradschool_theses/2582.
MLA Handbook (7th Edition):
Whipp, Michelle D. “Identification of blood protein in Louisiana clay sediment: subtitle.” 2011. Web. 01 Mar 2021.
Vancouver:
Whipp MD. Identification of blood protein in Louisiana clay sediment: subtitle. [Internet] [Masters thesis]. Louisiana State University; 2011. [cited 2021 Mar 01].
Available from: etd-04132012-173812 ; https://digitalcommons.lsu.edu/gradschool_theses/2582.
Council of Science Editors:
Whipp MD. Identification of blood protein in Louisiana clay sediment: subtitle. [Masters Thesis]. Louisiana State University; 2011. Available from: etd-04132012-173812 ; https://digitalcommons.lsu.edu/gradschool_theses/2582
University of Louisville
8.
Zhou, Lei.
Application of linear mixed-effects models to crossover designs.
Degree: MS, 2012, University of Louisville
URL: 10.18297/etd/1646
;
https://ir.library.louisville.edu/etd/1646
► Crossover design is a type of longitudinal study with each subject receiving different treatments in different time periods. It has been used frequently in…
(more)
▼ Crossover design is a type of longitudinal study with each
subject receiving different treatments in different time periods. It has been used frequently in the pharmaceutical industry and other medical fields to investigate the safety and efficacy of new drugs or new treatments. For
crossover studies, the treatment effects from the earlier period may be carried over to the later period, which is called the carry-over effect, the response may naturally change over different periods. How to assess treatment effect with accounting for all these features deserves further investigation. Linear mixed-effects (LME) model has been widely applied to analyze data resulted from longitudinal studies. In this project, we model treatment effects, period effects, and carryover effects using the LME for 2x2
crossover studies, where all subjects are randomly assigned to two sequences, and each
subject is treated subsequently with two treatments, the order of the treatments depends on its sequence. We first investigated the simple 2x2 design, where each
subject has only one response measurement under each treatment. Extensive simulations were carried out to compare the performance between LME and the traditional Grizzle's method. We extend the LME to the general 2x2
crossover studies, where the response under each treatment is taking over different time point. We applied our model to an endothelial progenitor cell (EPC) study, where each patient was exposed to either air (placebo) first then airborne particular matters (PM) or PM first then air. In each exposure condition, the EPC cells were measured right before the exposure (Pre), right after the exposure (Post), and the second day follow-up (FU). The results obtained from LME and traditional methods are compared.
Advisors/Committee Members: Kong, Maiying.
Subjects/Keywords: 2 x 2; Crossover; Linear
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APA (6th Edition):
Zhou, L. (2012). Application of linear mixed-effects models to crossover designs. (Masters Thesis). University of Louisville. Retrieved from 10.18297/etd/1646 ; https://ir.library.louisville.edu/etd/1646
Chicago Manual of Style (16th Edition):
Zhou, Lei. “Application of linear mixed-effects models to crossover designs.” 2012. Masters Thesis, University of Louisville. Accessed March 01, 2021.
10.18297/etd/1646 ; https://ir.library.louisville.edu/etd/1646.
MLA Handbook (7th Edition):
Zhou, Lei. “Application of linear mixed-effects models to crossover designs.” 2012. Web. 01 Mar 2021.
Vancouver:
Zhou L. Application of linear mixed-effects models to crossover designs. [Internet] [Masters thesis]. University of Louisville; 2012. [cited 2021 Mar 01].
Available from: 10.18297/etd/1646 ; https://ir.library.louisville.edu/etd/1646.
Council of Science Editors:
Zhou L. Application of linear mixed-effects models to crossover designs. [Masters Thesis]. University of Louisville; 2012. Available from: 10.18297/etd/1646 ; https://ir.library.louisville.edu/etd/1646
University of Canterbury
9.
Archer, Rosanna Juliet.
The Effects of Supramolecular Interactions on Iron(II) Spin Crossover Compounds.
Degree: PhD, Chemistry, 2013, University of Canterbury
URL: http://dx.doi.org/10.26021/6612
► Molecules with functional properties, especially ones that display spin crossover behaviour, are becoming increasingly well researched due to their potential applications as the active components…
(more)
▼ Molecules with functional properties, especially ones that display spin crossover behaviour, are becoming increasingly well researched due to their potential applications as the active components in molecular memory, optical displays or sensors.1,2 To this end, a series of Fe(II) coordination compounds utilising imidazolylimine and pyridylimine based ligands have been synthesised and their spin crossover behaviour analysed through a variety of techniques including variable temperature X-ray crystallography, magnetic susceptibility, surface reflectivity and UV-Visible spectroscopy. Light-Induced Excited Spin-State Trapping (LIESST) effects have also been analysed via photomagnetic measurements.
Particular attention was paid to the supramolecular interactions present within the
solid-state and the effect that these interactions may have on spin crossover behaviour. Subtle changes to the complexes through counter-anion exchange, solvent effects and ligand design were explored and careful structural analysis completed.
This study was separated into two distinct categories. The first describes the synthesis, structural characterisation and spin crossover behaviour of Fe(II) dinuclear triple helicates. Four dinuclear triple helicates have been synthesised, three of which display spin crossover behaviour. Weak LIESST effects were observed in two of these examples. Variation in the ligand field strength between the complexes was achieved through modification of the coordinating “head group” and differences between the flexibility of the ligand backbone were also explored.
The latter part of this study describes the synthesis, structural characterisation and spin crossover behaviour of novel Fe(II) mononuclear complexes. A series of related ligands which differ in the p-substituent have been synthesised and their coordination chemistry with Fe(II) metal ions examined. Subtle changes to the counter-anion and crystallised solvent molecules were also explored during this study. Five mononuclear Fe(II) complexes were shown to undergo spin crossover and the structural changes associated with the spin-state conversion have been analysed via variable temperature X-ray crystallography and compared with magnetic susceptibility measurements. Two complexes were also analysed for LIESST behaviour and these complexes showed full photo-excitation into the high-spin state at 10 K.
Subjects/Keywords: spin crossover; supramolecular chemistry
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APA (6th Edition):
Archer, R. J. (2013). The Effects of Supramolecular Interactions on Iron(II) Spin Crossover Compounds. (Doctoral Dissertation). University of Canterbury. Retrieved from http://dx.doi.org/10.26021/6612
Chicago Manual of Style (16th Edition):
Archer, Rosanna Juliet. “The Effects of Supramolecular Interactions on Iron(II) Spin Crossover Compounds.” 2013. Doctoral Dissertation, University of Canterbury. Accessed March 01, 2021.
http://dx.doi.org/10.26021/6612.
MLA Handbook (7th Edition):
Archer, Rosanna Juliet. “The Effects of Supramolecular Interactions on Iron(II) Spin Crossover Compounds.” 2013. Web. 01 Mar 2021.
Vancouver:
Archer RJ. The Effects of Supramolecular Interactions on Iron(II) Spin Crossover Compounds. [Internet] [Doctoral dissertation]. University of Canterbury; 2013. [cited 2021 Mar 01].
Available from: http://dx.doi.org/10.26021/6612.
Council of Science Editors:
Archer RJ. The Effects of Supramolecular Interactions on Iron(II) Spin Crossover Compounds. [Doctoral Dissertation]. University of Canterbury; 2013. Available from: http://dx.doi.org/10.26021/6612
10.
Gonzalo, Adrian.
Voies de formation des crossovers méiotiques chez une espèce allopolyploïde, le colza (Brassica napus) : Crossover Pathways of Brassica napus Allopolyploid Meiosis.
Degree: Docteur es, Biologie, 2017, Université Paris-Saclay (ComUE)
URL: http://www.theses.fr/2017SACLS352
► La recombinaison méiotique est au cœur de l'hérédité Mendélienne, de l'évolution et de l'amélioration des plantes, car elle assure, grâce aux crossovers, une transmission fidèle…
(more)
▼ La recombinaison méiotique est au cœur de l'hérédité Mendélienne, de l'évolution et de l'amélioration des plantes, car elle assure, grâce aux crossovers, une transmission fidèle des chromosomes et le brassage de l’information génétique au fil des générations. Deux voies de formation des crossovers coexistent chez les plantes. La voie principale (voie I) dépend de la protéine MSH4 (et de quelques autres). La voie secondaire ne produit que quelques crossovers (dits de voie II) au cours de la méiose d’une plante de type sauvage ; ils sont indépendants de MSH4 et leur nombre est limité par des protéines telles que FANCM. Si ces deux voies ont été bien décrites chez des espèces diploïdes, ce n’est pas le cas chez des plantes allopolyploïdes, pourtant très fréquentes parmi les plantes cultivées. Il s'agit là d'une lacune importante, car la présence de plusieurs jeux de chromosomes apparentés conduit à augmenter le nombre de partenaires susceptibles de former des crossovers et le nombre de copies de tous les gènes méiotiques, rendant la recombinaison méiotique plus complexe. Cette thèse vise à explorer l'interaction entre les voies de formation des crossovers et la polyploïdie en utilisant des mutants de colza (Brassica napus; AACC) et d’un de ces parents diploïdes (B. rapa; AA) pour deux gènes de la recombinaison méiotique.J'ai tout d'abord testé dans quelle mesure la formation de crossovers entre chromosomes homologues et entre homéologues (chromosomes A et C) est tributaire des voies I et II en évaluant l’effet d’une diminution du nombre de copies fonctionnelles de MSH4 sur le nombre de crossovers. J'ai montré que ce dernier n'est altéré que lorsque les deux copies MSH4 sont inactivées, toute autre combinaison de mutations conduisant au même nombre de crossovers inter-homologues que chez le sauvage. J'ai également montré que la proportion de crossovers de voie II chez des mutants msh4 de colza est bien supérieure à celles observées chez d’autres plantes mutantes pour msh4. Cette observation reste vraie chez des mutants msh4 de B. rapa, suggérant que la proportion accrue de crossovers de voie II n’est pas spécifique au colza, mais probablement une caractéristique des Brassicaceae. Chez des plantes allohaploïdes (AC) de colza, chez lesquelles les crossovers ne peuvent se former qu’entre homéologues, les copies MSH4 ne se compensent plus complétement ; le nombre de crossovers de voie I fluctue au contraire proportionnellement au dosage de MSH4, devenant presque nul lorsque toutes les copies sont inactivées. Mes résultats illustrent deux nouvelles propriétés spécifiques des crossovers entre homéologues: une plus grande sensibilité vis-à-vis du dosage MSH4 pour les crossovers de voie I et une plus faible efficacité des crossovers de voie II.Dans un second temps, j'ai caractérisé cytologiquement des mutants fancm de colza pour vérifier que l'augmentation des crossovers de voie II ne nuit pas à au bon déroulement de sa méiose. Cette question est restée en suspens, les mutants fancm de colza n’étant pas complètement nuls. Cet…
Advisors/Committee Members: Jenczewski, Eric (thesis director).
Subjects/Keywords: Meiose; Crossover; Polyploïdie; Colza; Meiosis; Crossover; Polyploidy; Rapeseed
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APA (6th Edition):
Gonzalo, A. (2017). Voies de formation des crossovers méiotiques chez une espèce allopolyploïde, le colza (Brassica napus) : Crossover Pathways of Brassica napus Allopolyploid Meiosis. (Doctoral Dissertation). Université Paris-Saclay (ComUE). Retrieved from http://www.theses.fr/2017SACLS352
Chicago Manual of Style (16th Edition):
Gonzalo, Adrian. “Voies de formation des crossovers méiotiques chez une espèce allopolyploïde, le colza (Brassica napus) : Crossover Pathways of Brassica napus Allopolyploid Meiosis.” 2017. Doctoral Dissertation, Université Paris-Saclay (ComUE). Accessed March 01, 2021.
http://www.theses.fr/2017SACLS352.
MLA Handbook (7th Edition):
Gonzalo, Adrian. “Voies de formation des crossovers méiotiques chez une espèce allopolyploïde, le colza (Brassica napus) : Crossover Pathways of Brassica napus Allopolyploid Meiosis.” 2017. Web. 01 Mar 2021.
Vancouver:
Gonzalo A. Voies de formation des crossovers méiotiques chez une espèce allopolyploïde, le colza (Brassica napus) : Crossover Pathways of Brassica napus Allopolyploid Meiosis. [Internet] [Doctoral dissertation]. Université Paris-Saclay (ComUE); 2017. [cited 2021 Mar 01].
Available from: http://www.theses.fr/2017SACLS352.
Council of Science Editors:
Gonzalo A. Voies de formation des crossovers méiotiques chez une espèce allopolyploïde, le colza (Brassica napus) : Crossover Pathways of Brassica napus Allopolyploid Meiosis. [Doctoral Dissertation]. Université Paris-Saclay (ComUE); 2017. Available from: http://www.theses.fr/2017SACLS352
Université Paris-Sud – Paris XI
11.
Basu Roy, Sayantani.
Répartition des crossovers méiotiques : hétérogénéité, modélisation de l'interférence, interaction entre voies de formation : Distribution of meiotic crossovers : heterogeneity, modeling interference, inter-pathway crosstalk.
Degree: Docteur es, Biologie, 2014, Université Paris-Sud – Paris XI
URL: http://www.theses.fr/2014PA112051
► Dans la plupart des organismes, les crossovers se formant au cours de la méiose sont interférérents : deux crossovers sont rarement à proximité. Nous avons…
(more)
▼ Dans la plupart des organismes, les crossovers se formant au cours de la méiose sont interférérents : deux crossovers sont rarement à proximité. Nous avons étudié ce phénomène en détail dans la plante modèle Arabidopsis thaliana en utilisant une grande population de rétro-croisements, en méiose mâle et en méiose femelle. Nous avons utilisé le modèle Gamma à deux voies, superposant à la voie interférente une proportion p de crossovers d'une deuxième voie non interférente. La méiose femelle montre une interférence plus élevée et une proportion p plus faible que la méiose mâle. Par ailleurs nos comparaisons intra-chromosomiques concluent qu'il existe des variations d'interférence entre le bras gauche et le bras droit d'une part et entre la partie centrale et les régions distales d'autre part. Nous avons ensuite développé des tests statistiques qui ont révélé des hétérogénéités dans la proportion p le long des chromosomes. De telles variations ont ensuite été trouvées dans un jeu de données de tomate où notre analyse statistique nous a permis de montrer pour la première fois sur un organisme «sauvage» que la deuxième voie était très peu interférente et qu'en fait les deux voies avaient un peu de « cross-talk ». Vu que la limitation la plus sévère des modèles utilisés jusqu'à présent est l'hypothèse de constance du paramètre p, nous avons développé un modèle généralisé où les deux voies peuvent avoir des paysages de recombinaison différents. Ce modèle nommé PSL-GS a été implémenté en logiciel et testé sur des données simulées et sur trois jeux de données de plantes. L'utilisation du critère BIC suggère que tout comme chez la tomate, les paysages de recombinaison d'Arabidopsis et du maïs sont différents entre les 2 voies.
For most organisms, crossovers forming during meiosis exhibit crossover interference – nearby crossovers are rare. This phenomenon was studied in great detail in Arabidopsis thaliana using a large backcross population for male and female meiosis. We used the gamma two-pathway model by superposing proportion (1- p) of interfering crossovers with p of non-interfering crossovers. It was observed that female meiosis shows higher interference but lower proportion of non-interfering crossovers than male meiosis. Further intra-chromosomal interference comparisons conclude that there are variations between (a) left and right arms, and (b) the central versus distal regions of a chromosome. Then statistical tests revealed heterogeneities in the non-interfering crossover proportion along chromosomes. Thereafter various statistical tools developed to examine a very novel wild-type tomato data annotating crossover positions from both pathways provided evidence for ‘cross-talk’ between the two pathways of crossover formation as opposed to being independent. Finally a model named Pathway-Specific Landscapes Gamma-Sprinkling (PSL-GS) incorporating chromosomal non-uniformity in the individual pathways has been proposed to extend present state-of-the-art interference modeling which consider both pathways to be uniform…
Advisors/Committee Members: Martin, Olivier C. (thesis director).
Subjects/Keywords: Méiose; Crossovers; Interférence entre crossovers; Deux voies de formation des crossover; Meiosis; Crossovers; Crossover interference; Two crossover formation pathways
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APA ·
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APA (6th Edition):
Basu Roy, S. (2014). Répartition des crossovers méiotiques : hétérogénéité, modélisation de l'interférence, interaction entre voies de formation : Distribution of meiotic crossovers : heterogeneity, modeling interference, inter-pathway crosstalk. (Doctoral Dissertation). Université Paris-Sud – Paris XI. Retrieved from http://www.theses.fr/2014PA112051
Chicago Manual of Style (16th Edition):
Basu Roy, Sayantani. “Répartition des crossovers méiotiques : hétérogénéité, modélisation de l'interférence, interaction entre voies de formation : Distribution of meiotic crossovers : heterogeneity, modeling interference, inter-pathway crosstalk.” 2014. Doctoral Dissertation, Université Paris-Sud – Paris XI. Accessed March 01, 2021.
http://www.theses.fr/2014PA112051.
MLA Handbook (7th Edition):
Basu Roy, Sayantani. “Répartition des crossovers méiotiques : hétérogénéité, modélisation de l'interférence, interaction entre voies de formation : Distribution of meiotic crossovers : heterogeneity, modeling interference, inter-pathway crosstalk.” 2014. Web. 01 Mar 2021.
Vancouver:
Basu Roy S. Répartition des crossovers méiotiques : hétérogénéité, modélisation de l'interférence, interaction entre voies de formation : Distribution of meiotic crossovers : heterogeneity, modeling interference, inter-pathway crosstalk. [Internet] [Doctoral dissertation]. Université Paris-Sud – Paris XI; 2014. [cited 2021 Mar 01].
Available from: http://www.theses.fr/2014PA112051.
Council of Science Editors:
Basu Roy S. Répartition des crossovers méiotiques : hétérogénéité, modélisation de l'interférence, interaction entre voies de formation : Distribution of meiotic crossovers : heterogeneity, modeling interference, inter-pathway crosstalk. [Doctoral Dissertation]. Université Paris-Sud – Paris XI; 2014. Available from: http://www.theses.fr/2014PA112051
Universiteit Utrecht
12.
Mulder, D.J.
Job crafting: Het crossover effect van job crafting tussen werk koppels.
Degree: 2012, Universiteit Utrecht
URL: http://dspace.library.uu.nl:8080/handle/1874/251893
► Het doel van dit onderzoek is het analyseren van de processen die ten grondslag liggen aan job crafting. Job crafting beschrijft de wijze waarop werknemers…
(more)
▼ Het doel van dit onderzoek is het analyseren van de processen die ten grondslag liggen aan job crafting. Job crafting beschrijft de wijze waarop werknemers kansen gebruiken om actief taken en interacties binnen hun baan te veranderen zodat deze beter aansluiten bij eigen behoeften en competenties. Er wordt een
crossover van job crafting verwacht, die wordt beïnvloedt door empathie en sociabiliteit. Daarnaast wordt verwacht dat job crafting: het zoeken naar hulpbronnen, het zoeken naar uitdagingen en het verminderen van taakeisen een verband heeft met bevlogenheid en prestatie: contextuele prestatie, taakprestatie en adaptieve prestatie. Dit onderzoek is uitgevoerd onder 122 respondenten, waarbinnen in totaal 55 koppels zijn gevormd. De resultaten van deze studie laten een positieve significante samenhang zien tussen het zoeken naar uitdagingen en bevlogenheid, taakprestatie en adaptieve prestatie. Er werd geen bewijs gevonden voor de
crossover van job crafting. Nader onderzoek moet zich richten op de samenhang tussen job crafting, met name het zoeken naar hulpbronnen, en prestatie. Dit zou kunnen leiden tot de ontwikkeling van een training of interventie die job crafting stimuleert, en zo ook prestatie stimuleert.
Advisors/Committee Members: Peeters, M..
Subjects/Keywords: Sociale Wetenschappen; Job crafting; crossover; bevlogenheid; prestatie
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APA (6th Edition):
Mulder, D. J. (2012). Job crafting: Het crossover effect van job crafting tussen werk koppels. (Masters Thesis). Universiteit Utrecht. Retrieved from http://dspace.library.uu.nl:8080/handle/1874/251893
Chicago Manual of Style (16th Edition):
Mulder, D J. “Job crafting: Het crossover effect van job crafting tussen werk koppels.” 2012. Masters Thesis, Universiteit Utrecht. Accessed March 01, 2021.
http://dspace.library.uu.nl:8080/handle/1874/251893.
MLA Handbook (7th Edition):
Mulder, D J. “Job crafting: Het crossover effect van job crafting tussen werk koppels.” 2012. Web. 01 Mar 2021.
Vancouver:
Mulder DJ. Job crafting: Het crossover effect van job crafting tussen werk koppels. [Internet] [Masters thesis]. Universiteit Utrecht; 2012. [cited 2021 Mar 01].
Available from: http://dspace.library.uu.nl:8080/handle/1874/251893.
Council of Science Editors:
Mulder DJ. Job crafting: Het crossover effect van job crafting tussen werk koppels. [Masters Thesis]. Universiteit Utrecht; 2012. Available from: http://dspace.library.uu.nl:8080/handle/1874/251893
Rochester Institute of Technology
13.
Nogaj, Adam.
Establishing parameters for problem difficulty in permutation-based genetic algorithms.
Degree: Computer Science (GCCIS), 2011, Rochester Institute of Technology
URL: https://scholarworks.rit.edu/theses/252
► This thesis examines the performance of genetic algorithm (GA) crossover techniques within two problems: n-queens with poison (NQWP) and processor scheduling (PS). Each problem was…
(more)
▼ This thesis examines the performance of genetic algorithm (GA)
crossover techniques
within two problems: n-queens with poison (NQWP) and processor scheduling (PS).
Each problem was analyzed at sizes of 32, 64, and 128, referring to number of queens
to be placed and number of single-time-unit processes to be scheduled, respectively.
The specific
crossover techniques studied were cycle
crossover, order
crossover, partially mapped
crossover, merging
crossover, and one-point, two-point, and uniform
signature representation
crossover, in addition to various greedy approaches. In conjunction with tests that vary
crossover techniques, experimentation was performed to
determine what percentage of problem constraints (poisoned squares for NQWP or
precedence relationships between tasks for PS) makes the problems most difficult to
solve, that is, the constraint densities at which optimal solutions require the highest
number of GA fitness evaluations. While minor fluctuations in difficulty occur upon
variations in fitness function and problem size, the NQWP problem is most difficult around a constraint density of 0.8 and the PS problem is most difficult around
constraint densities of 0.2 to 0.3. Even within an individual problem, one
crossover
technique does not irreproachably outperform others. However, cycle
crossover stands
out in its performance in the PS problem while merging
crossover and uniform signature crossovers most often perform well for NQWP.
Advisors/Committee Members: Gaborski, Roger.
Subjects/Keywords: Crossover; Genetic algorithms; N-queens; Processor scheduling
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APA (6th Edition):
Nogaj, A. (2011). Establishing parameters for problem difficulty in permutation-based genetic algorithms. (Thesis). Rochester Institute of Technology. Retrieved from https://scholarworks.rit.edu/theses/252
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Nogaj, Adam. “Establishing parameters for problem difficulty in permutation-based genetic algorithms.” 2011. Thesis, Rochester Institute of Technology. Accessed March 01, 2021.
https://scholarworks.rit.edu/theses/252.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Nogaj, Adam. “Establishing parameters for problem difficulty in permutation-based genetic algorithms.” 2011. Web. 01 Mar 2021.
Vancouver:
Nogaj A. Establishing parameters for problem difficulty in permutation-based genetic algorithms. [Internet] [Thesis]. Rochester Institute of Technology; 2011. [cited 2021 Mar 01].
Available from: https://scholarworks.rit.edu/theses/252.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Nogaj A. Establishing parameters for problem difficulty in permutation-based genetic algorithms. [Thesis]. Rochester Institute of Technology; 2011. Available from: https://scholarworks.rit.edu/theses/252
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Penn State University
14.
Dholakia, Ruchita.
A Model For The Analysis Of Carryover Effects In A Three-period,three-treatment Crossover Trial For Asthma Patients.
Degree: 2013, Penn State University
URL: https://submit-etda.libraries.psu.edu/catalog/19005
► Abstract Background: A crossover trial design is a repeated measures assignment such that every subject is assigned different treatments in different time periods. This design…
(more)
▼ Abstract
Background: A
crossover trial design is a repeated measures assignment such that every
subject is assigned different treatments in different time periods. This design is more efficient as each
subject acts as his own control and one major criticism of this trial is a carryover effect. A carryover effect is defined as the effect of the treatment from the previous time period on the response at the current time period. A
crossover trial design is appropriate when the carryover effect can be assumed to be negligible or the trial has incorporated a sufficient duration of washout period to reduce any carryover bias. This study evaluates the presence of a carryover effect as well as the difference in residual effects for different treatments in a three x three
crossover trial with a pseudo-washout period. The trial extended over forty-eight weeks with sixteen weeks in each treatment arm. The first four weeks of each sixteen week period was considered as washout.
Objectives: This study develops a model to analyze the carryover effect and its decay in a three-period
crossover trial comparing the responses of asthmatic kids to three add-on therapies (BADGER trial). The primary source of data for this analysis was the daily diary maintained by the subjects in the trial. The study attempts to distinguish the decay pattern for the various therapies to establish the need/appropriateness of the washout period.
Methods: The analysis utilizes data collected for the BADGER trial. The BADGER trial recruited patients, 6 to 17 years of age between March 2007 and July 2008, at Childhood Asthma Research and Education (CARE) Network centers. Analysis of Variance comparing summated outcomes for drug sequences was used for a preliminary test of carryover. Non-parametric and semi-parametric survival analysis was used to compare the carryover effects for different combinations of current and previous treatments. The primary outcome variables used included asthma control days (ACD), symptom free days (SFD), rescue free days (RFD), % change in FEV levels, and proportion of differential responders.
Results: A preliminary analysis to check for carryover was not significant (p-value =0.30). A Kaplan-Meier analysis for ACD during the washout period showed a significant carryover for LABA (p-value = 0.02) when it was followed by ICS and for LTRA (p-value = 0.02) when it was followed by LABA. Both of these are true under the assumption that in the first period a
subject does not have a residual effect of any previous treatment. As expected, the change in FEV from the baseline to the end of the washout for the various groups was not significant for ICS(p-value = 0.0845), or LABA(p-value = 0.8404), or LTRA (p-value=0.7263). The proportional of responders favorable to LABA as compared to either ICS or LTRA was significant for both the 12 and 16 week intervals.
Conclusion: The trial did not show a strong evidence for a carryover effect, though we have some statistical evidence to show that the carryover to the next period also depends on the…
Advisors/Committee Members: David Theodore Mauger, Thesis Advisor/Co-Advisor, Jeffrey David Yanosky, Thesis Advisor/Co-Advisor, Vernon Michael Chinchilli, Thesis Advisor/Co-Advisor.
Subjects/Keywords: crossover trial; carryover; Kaplan-meier; washout
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APA ·
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MLA ·
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APA (6th Edition):
Dholakia, R. (2013). A Model For The Analysis Of Carryover Effects In A Three-period,three-treatment Crossover Trial For Asthma Patients. (Thesis). Penn State University. Retrieved from https://submit-etda.libraries.psu.edu/catalog/19005
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Dholakia, Ruchita. “A Model For The Analysis Of Carryover Effects In A Three-period,three-treatment Crossover Trial For Asthma Patients.” 2013. Thesis, Penn State University. Accessed March 01, 2021.
https://submit-etda.libraries.psu.edu/catalog/19005.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Dholakia, Ruchita. “A Model For The Analysis Of Carryover Effects In A Three-period,three-treatment Crossover Trial For Asthma Patients.” 2013. Web. 01 Mar 2021.
Vancouver:
Dholakia R. A Model For The Analysis Of Carryover Effects In A Three-period,three-treatment Crossover Trial For Asthma Patients. [Internet] [Thesis]. Penn State University; 2013. [cited 2021 Mar 01].
Available from: https://submit-etda.libraries.psu.edu/catalog/19005.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Dholakia R. A Model For The Analysis Of Carryover Effects In A Three-period,three-treatment Crossover Trial For Asthma Patients. [Thesis]. Penn State University; 2013. Available from: https://submit-etda.libraries.psu.edu/catalog/19005
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Université Paris-Sud – Paris XI
15.
Khademian, Hossein.
Caractérisation d’un point chaud de recombinaison méiotique chez Arabidopsis thaliana : Characterization of a meiotic recombination hotspot in Arabidopsis thaliana.
Degree: Docteur es, Sciences du végétal, 2012, Université Paris-Sud – Paris XI
URL: http://www.theses.fr/2012PA112051
► La recombinaison méiotique initiée en prophase I de méiose génère soit des crossing-over (COs), qui sont des échanges réciproques entre segments chromosomiques, ou des conversions…
(more)
▼ La recombinaison méiotique initiée en prophase I de méiose génère soit des crossing-over (COs), qui sont des échanges réciproques entre segments chromosomiques, ou des conversions géniques non associées aux COs (NCOs). Les deux types d'événements se produisent dans de petites régions (moins de 10 kilobases) appelées points chauds, qui sont distribuées de manière non homogène le long des chromosomes. L'objectif de ma thèse était la caractérisation d'un point chaud de recombinaison méiotique (nommée 14a) chez Arabidopsis thaliana (i) dans différentes accessions (ii) dans le mutant msh4, un gène impliqué dans la formation des COs. Dans les deux hybrides ColxLer et ColxWs (i) 14a a un taux très élevé de COs 0,85% et 0,49%, respectivement (ii) Les COs sont regroupés dans deux petites régions de quelques kilobases, 14a1 et 14a2 avec une distribution de type gaussienne observée aux points chauds décrits dans d'autres espèces (iii) 14a1 est aussi un point chaud de NCO avec un taux aussi élevé que celui des COs (0,5%) dans ColxLer (iv) un biais de l'initiation de recombinaison a été trouvé dans 14a1 aussi bien pour les COs que les NCOs dans le fond génétique ColxLer.Une réduction de la fréquence de CO a été observée dans le mutant msh4 dans le fond génétique ColxLer à 14a1 et 14a2 (6,4% et 18,7% par rapport au sauvage). Cela confirme le rôle précédemment connu de la protéine MSH4 impliqué dans la formation de CO. La fréquence de NCO à 14a1 est similaire à celle observéedans le fond sauvage. Le rôle des H3K4 histones trimethyltransferase d’Arabidopsis dans la recombinaison méiotique (comme précédemment observé comme Set1 chez S. cerevisiae ou PRDM9 chez les mammifères) a également été étudiée. Aucun des dix gènes d’histones méthyltransférase étudié n'a montré de rôle dans la méiose. Cela pourrait être dû à (i) une forte redondance de la fonction entre les protéines (ii) une autre histone méthyltransférase en charge de l'étiquetage des points chauds de recombinaison méiotique (plus de 29 putatif histone méthyltransférase ont été identifiés dans le génome d'Arabidopsis!) (iii) contrairement à S. cerevisiae, les souris et l'homme, un autre mécanisme de contrôle épigénétique de la recombinaison méiotique.
Meiotic recombination initiated in prophase I of meiosis generates either crossovers (COs), which are reciprocal exchanges between chromosome segments, or gene conversion not associated to crossovers (NCOs). Both kinds of events occur in narrow regions (less than 10 kilobases) called hotspots, which are distributed non-homogenously along chromosomes. The aim of my PhD was the characterization of a hotspot of meiotic recombination (named 14a) in Arabidopsis thaliana (i) across different accessions (ii) in msh4 mutant, a gene involved in CO formation. In both ColxLer and ColxWs hybrids (i) 14a had a very high rate of COs 0.85% and 0.49%, respectively (ii) COs clustered in two small regions of a few kilobases, 14a1 and 14a2 with typical Gaussian curve distribution observed in other organisms (iii) 14a1 was also a hotspot of NCO…
Advisors/Committee Members: Mézard, Christine (thesis director).
Subjects/Keywords: Arabidopsis thaliana; Recombinaison méiotique; Point chaud; Crossover; Non-crossover; Conversion génique; Plante; Arabidopsis thaliana; Meiotic recombination; Hotspot; Crossover; Non-crossover; Gene conversion; Plant
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APA (6th Edition):
Khademian, H. (2012). Caractérisation d’un point chaud de recombinaison méiotique chez Arabidopsis thaliana : Characterization of a meiotic recombination hotspot in Arabidopsis thaliana. (Doctoral Dissertation). Université Paris-Sud – Paris XI. Retrieved from http://www.theses.fr/2012PA112051
Chicago Manual of Style (16th Edition):
Khademian, Hossein. “Caractérisation d’un point chaud de recombinaison méiotique chez Arabidopsis thaliana : Characterization of a meiotic recombination hotspot in Arabidopsis thaliana.” 2012. Doctoral Dissertation, Université Paris-Sud – Paris XI. Accessed March 01, 2021.
http://www.theses.fr/2012PA112051.
MLA Handbook (7th Edition):
Khademian, Hossein. “Caractérisation d’un point chaud de recombinaison méiotique chez Arabidopsis thaliana : Characterization of a meiotic recombination hotspot in Arabidopsis thaliana.” 2012. Web. 01 Mar 2021.
Vancouver:
Khademian H. Caractérisation d’un point chaud de recombinaison méiotique chez Arabidopsis thaliana : Characterization of a meiotic recombination hotspot in Arabidopsis thaliana. [Internet] [Doctoral dissertation]. Université Paris-Sud – Paris XI; 2012. [cited 2021 Mar 01].
Available from: http://www.theses.fr/2012PA112051.
Council of Science Editors:
Khademian H. Caractérisation d’un point chaud de recombinaison méiotique chez Arabidopsis thaliana : Characterization of a meiotic recombination hotspot in Arabidopsis thaliana. [Doctoral Dissertation]. Université Paris-Sud – Paris XI; 2012. Available from: http://www.theses.fr/2012PA112051
University of Cambridge
16.
Lawrence, Emma Jane.
Identifying natural modifiers of meiotic crossover frequency in Arabidopsis thaliana.
Degree: PhD, 2019, University of Cambridge
URL: https://www.repository.cam.ac.uk/handle/1810/289733
► During meiosis, homologous chromosomes pair and undergo reciprocal genetic exchange, producing crossovers. This generates genetic diversity and is required for balanced homolog segregation. Despite the…
(more)
▼ During meiosis, homologous chromosomes pair and undergo reciprocal genetic exchange, producing crossovers. This generates genetic diversity and is required for balanced homolog segregation. Despite the critical functions of crossovers, their frequency and distribution varies extensively within and between species. This crossover variation can be caused by trans-modifiers within populations, which encode diffusible molecules that influence crossover formation elsewhere in the genome. This project utilised natural accessions of Arabidopsis thaliana to identify trans-modifying loci underlying crossover variation within the species.
I performed Quantitative Trait Loci (QTL) mapping using a fluorescence-based crossover reporter system to measure recombination frequency in a genomic interval on chromosome 3, termed 420. Mapping in a Col-420 × Bur-0 F2 population revealed four major recombination QTLs (rQTLs) that influence crossover frequency. A novel recessive rQTL on chromosome 1 that reduced crossovers within the interval was fine-mapped to a premature stop codon in TATA Binding Protein (TBP)-associated factor 4b (TAF4b) in Bur-0 (taf4b-1). TAF4b is a subunit of the TFIID complex, a multi-protein general transcription factor complex comprising TBP and numerous TAFs that forms a component of the pre-initiation complex that recruits RNA polymerase II to promoters. Transformation-based complementation experiments and the isolation of several independent taf4b alleles provided genetic proof that TAF4b is essential for wild-type levels of crossover within 420. Analysis of the prevalence of the taf4b-1 mutation in the global Arabidopsis accession collection demonstrated its specificity to three accessions in the British Isles.
A combination of cytology, genetic analysis using additional fluorescent reporter lines, and sequencing in F2 recombinant populations demonstrated a genome-wide reduction in crossover frequency in taf4b-1. In addition, RNA sequencing identified numerous transcriptional changes in taf4b-1. Both up- and down-regulated gene sets displayed significant enrichment for genes that are predominantly expressed in meiocytes, and several gene ontology terms pertaining to protein modification and meiotic processes.
These results further demonstrate the existence of genetic modifiers of crossover frequency in natural populations of A. thaliana, and the characterisation of a novel trans-modifier of recombination, TAF4b. This signifies a novel function for TAF4b in Arabidopsis, and further enhances our understanding of the molecular factors controlling the frequency and distribution of meiotic crossovers in plants.
Subjects/Keywords: Arabidopsis; meiosis; recombination; crossover; variation; transcription
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APA (6th Edition):
Lawrence, E. J. (2019). Identifying natural modifiers of meiotic crossover frequency in Arabidopsis thaliana. (Doctoral Dissertation). University of Cambridge. Retrieved from https://www.repository.cam.ac.uk/handle/1810/289733
Chicago Manual of Style (16th Edition):
Lawrence, Emma Jane. “Identifying natural modifiers of meiotic crossover frequency in Arabidopsis thaliana.” 2019. Doctoral Dissertation, University of Cambridge. Accessed March 01, 2021.
https://www.repository.cam.ac.uk/handle/1810/289733.
MLA Handbook (7th Edition):
Lawrence, Emma Jane. “Identifying natural modifiers of meiotic crossover frequency in Arabidopsis thaliana.” 2019. Web. 01 Mar 2021.
Vancouver:
Lawrence EJ. Identifying natural modifiers of meiotic crossover frequency in Arabidopsis thaliana. [Internet] [Doctoral dissertation]. University of Cambridge; 2019. [cited 2021 Mar 01].
Available from: https://www.repository.cam.ac.uk/handle/1810/289733.
Council of Science Editors:
Lawrence EJ. Identifying natural modifiers of meiotic crossover frequency in Arabidopsis thaliana. [Doctoral Dissertation]. University of Cambridge; 2019. Available from: https://www.repository.cam.ac.uk/handle/1810/289733
17.
Gustavsson, Elin.
Crossover på biblioteket : En studie i hur folkbibliotek arbetar medcrossoverlitteratur.
Degree: Sociology, 2014, Umeå University
URL: http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-105048
► Syftet med denna uppsats är att belysa folkbibliotekens arbete med crossoverlitteratur samt vilka möjligheter begreppet och fenomonet ger biblioteken, främst när det kommer till…
(more)
▼ Syftet med denna uppsats är att belysa folkbibliotekens arbete med crossoverlitteratur samt vilka möjligheter begreppet och fenomonet ger biblioteken, främst när det kommer till marknadsföring. De tre forskninsfrågorna rörde definition av crossoverlitteratur, placering och marknadsföring av crossoverlitteratur samt presentation av crossoverlitteratur i bibliotekskatalogen. De besvaras genom kvalitativa semistrukturerade telefonintervjuer med bibliotekarier på sex olika bibliotek samt genom en granskning av några crossovertitlar i bibliotekens kataloger. Slutsatser som drogs var att det är ett svårdefinierat begrepp och att litteraturen fortfarande värderas olika beroende vilken den tilltänkta åldersgruppen är. Det är fortfarande en tydlig indelning mellan ungdom och vuxen på de flesta bibliotek när det gäller placering och marknadsföring, men bibliotekarierna skulle vilja att gränsen blev mindre tydlig.
Subjects/Keywords: crossover; ungdomslitteratur; unga vuxna; marknadsföring; kunskapsorganisering
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APA (6th Edition):
Gustavsson, E. (2014). Crossover på biblioteket : En studie i hur folkbibliotek arbetar medcrossoverlitteratur. (Thesis). Umeå University. Retrieved from http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-105048
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Gustavsson, Elin. “Crossover på biblioteket : En studie i hur folkbibliotek arbetar medcrossoverlitteratur.” 2014. Thesis, Umeå University. Accessed March 01, 2021.
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-105048.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Gustavsson, Elin. “Crossover på biblioteket : En studie i hur folkbibliotek arbetar medcrossoverlitteratur.” 2014. Web. 01 Mar 2021.
Vancouver:
Gustavsson E. Crossover på biblioteket : En studie i hur folkbibliotek arbetar medcrossoverlitteratur. [Internet] [Thesis]. Umeå University; 2014. [cited 2021 Mar 01].
Available from: http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-105048.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Gustavsson E. Crossover på biblioteket : En studie i hur folkbibliotek arbetar medcrossoverlitteratur. [Thesis]. Umeå University; 2014. Available from: http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-105048
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Delft University of Technology
18.
Hoeffelman, M.L. (author).
Performance of Crossovers in the Dutch Railway Network: Case Study for Amsterdam and Rotterdam.
Degree: 2012, Delft University of Technology
URL: http://resolver.tudelft.nl/uuid:1471897b-3caf-4b61-90c6-cb30158b7ed4
► ProRail Traffic Control would like to have examined what the performance of crossovers for rescheduling is in case of partial obstructions. The need for quantitative…
(more)
▼ ProRail Traffic Control would like to have examined what the performance of crossovers for rescheduling is in case of partial obstructions. The need for quantitative information about the performance of crossovers in The Netherlands has grown. The research is intended to fill this knowledge gap by investigating the performance of crossovers in The Netherlands in a quantitative manner for two typical corridors. Therefore, the main research question is stated as follows: What is the performance of crossovers with respect to reliability (benefits) and life-cycle costs when rescheduling takes place? The focus in this research is on IVO switches (crossovers in between stations) that are only used for rescheduling. A
crossover is a pair of switches that connects two parallel tracks and enables transfer from one track to the other track. The research question has been explored on two typical corridors in the Dutch railway network: corridor Amsterdam: Amsterdam Riekerpolder aansluiting (Asra) – Amsterdam Bijlmer ArenA (Asb)/Diemen Zuid (Dmnz) and corridor Rotterdam: Rotterdam Centraal (Rtd) – Gouda (Gd). Several methods and tools have been used. First, a disruption analysis of the applied partial rescheduling (VSM: VerSperringsMaatregel) in 2011 has been done. The microscopic application TOON has been used to analyze disrupted train operations. Database MUIS contains manually added reports about rescheduling inputted by traffic controllers. With these two tools, similarities and differences between the applied VSM and the real processes and reports from traffic control have been analyzed. Furthermore, insight into the usage of crossovers during rescheduling has been obtained. To get insight into delays and the propagation, data from the Monitoringsystem has been used. The Monitoringsystem generates couplings between train delays. Second, a simulation study of case study Rotterdam has been performed. The microscopic simulation tool OpenTrack has been used to analyze the rescheduling and
crossover usage during partial obstruction between Rotterdam Noord Goederen (Rtng) and Nieuwerkerk a/d IJssel (Nwk) (VSM 25.070). Three scenarios have been analyzed: the reference situation: maintaining crossovers at Nieuwerkerk IVO wissels (Nwki) and Moordrecht overloopwissels (Mdo), scenario 1: a
crossover at Capelle Schollevaar overloopwissels (Cpso) instead Nwki and scenario 2: both crossovers at Nwki and Mdo are removed. The scenarios have been evaluated through estimations of passenger-, operator- and infra manager costs. Important conclusions that could be drawn from the analyses are that most disruptions that needed partial VSM were caused by defect trains rather than infrastructure related defects. Furthermore, the largest part of the rescheduling went according to the VSM. Although, some disruptions were too short and therefore rescheduling was partly executed according to the VSM. In both case studies crossovers were frequently used during rescheduling. Especially during the first phase–when trains are trapped–crossovers are needed…
Advisors/Committee Members: Van Arem, B. (mentor), Hansen, I.A. (mentor), Goverde, R.M.P. (mentor), Steenbergen, M.J.M.M. (mentor), Van Neerrijnen, R.J.M. (mentor), Schaafsma, A.A.M. (mentor).
Subjects/Keywords: railway network; crossover; train operations; rescheduling
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APA ·
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APA (6th Edition):
Hoeffelman, M. L. (. (2012). Performance of Crossovers in the Dutch Railway Network: Case Study for Amsterdam and Rotterdam. (Masters Thesis). Delft University of Technology. Retrieved from http://resolver.tudelft.nl/uuid:1471897b-3caf-4b61-90c6-cb30158b7ed4
Chicago Manual of Style (16th Edition):
Hoeffelman, M L (author). “Performance of Crossovers in the Dutch Railway Network: Case Study for Amsterdam and Rotterdam.” 2012. Masters Thesis, Delft University of Technology. Accessed March 01, 2021.
http://resolver.tudelft.nl/uuid:1471897b-3caf-4b61-90c6-cb30158b7ed4.
MLA Handbook (7th Edition):
Hoeffelman, M L (author). “Performance of Crossovers in the Dutch Railway Network: Case Study for Amsterdam and Rotterdam.” 2012. Web. 01 Mar 2021.
Vancouver:
Hoeffelman ML(. Performance of Crossovers in the Dutch Railway Network: Case Study for Amsterdam and Rotterdam. [Internet] [Masters thesis]. Delft University of Technology; 2012. [cited 2021 Mar 01].
Available from: http://resolver.tudelft.nl/uuid:1471897b-3caf-4b61-90c6-cb30158b7ed4.
Council of Science Editors:
Hoeffelman ML(. Performance of Crossovers in the Dutch Railway Network: Case Study for Amsterdam and Rotterdam. [Masters Thesis]. Delft University of Technology; 2012. Available from: http://resolver.tudelft.nl/uuid:1471897b-3caf-4b61-90c6-cb30158b7ed4
University of Illinois – Urbana-Champaign
19.
Zhu, Guojun.
BEC-BCS crossover with Feshbach resonance for three-hyperfine-species model.
Degree: PhD, 0240, 2012, University of Illinois – Urbana-Champaign
URL: http://hdl.handle.net/2142/31105
► The BEC-BCS crossover problem has been intensively studied both theoretically and experimentally largely thanks to Feshbach resonances which allow us to tune the effective interaction…
(more)
▼ The BEC-BCS
crossover problem has been intensively studied both theoretically and experimentally largely thanks to Feshbach resonances which allow us to tune the effective interaction between alkali atoms. In a Feshbach resonance, the effective s-wave scattering length grows when one moves toward the resonance point, and eventually diverges at this point. There is one characteristic energy scale, δ
c, defined as, in the negative side of the resonance point, the detuning energy at which the weight of the bound state shifts from predominatedly in the open-channel to predominated in the closed-channel. When the many-body energy scale (e.g. the Fermi energy, E
F) is larger than δ
c, the closed-channel weight is significant and has to be included in the many-body theory. Furthermore, when two channels share a hyperfine species, the Pauli exclusion between fermions from two channels also needs to be taken into consideration in the many-body theory.
The current thesis addresses the above problem in detail. A set of gap equations and number equations are derived at the mean-field level. The fermionic and bosonic excitation spectra are then derived. Assuming that the uncoupled bound-state of the closed-channel in resonance is much smaller than the inter-particle distance, as well as the s-wave scattering length, a
s, we find that the basic equations in the single-channel
crossover model are still valid. The correction first comes from the existing of the finite chemical potential and additional counting complication due to the closed-channel. These two corrections need to be included into the mean-field equations, i.e. the gap equations and the number equations, and be solved self-consistently. Then the correction due to the inter-channel Pauli exclusion is in the order of the ratio of the Fermi energy and the Zeeman energy difference between two channels, E
F/η, which can be analyzed perturbatively over the previous corrections.
Fermionic and bosonic excitation modes are studied. Similarly as the mean-field result, the basic structure follows that of the single-channel model, and the correction due to the inter-channel Pauli exclusion can be treated perturbatively with expansion parameter in the order of E
F/η. In the bosonic excitation, a new out-of-sync phase mode emerges for the two-component order parameters. It is nevertheless gapped at the the pair-breaking energy.
Advisors/Committee Members: Leggett, Anthony J. (advisor), Baym, Gordon A. (Committee Chair), Leggett, Anthony J. (committee member), DeMarco, Brian L. (committee member), Willenbrock, Scott S. (committee member).
Subjects/Keywords: superconductivity; crossover; Bose-Einstein condensation; alkali gas
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APA ·
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Export
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Manager
APA (6th Edition):
Zhu, G. (2012). BEC-BCS crossover with Feshbach resonance for three-hyperfine-species model. (Doctoral Dissertation). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/31105
Chicago Manual of Style (16th Edition):
Zhu, Guojun. “BEC-BCS crossover with Feshbach resonance for three-hyperfine-species model.” 2012. Doctoral Dissertation, University of Illinois – Urbana-Champaign. Accessed March 01, 2021.
http://hdl.handle.net/2142/31105.
MLA Handbook (7th Edition):
Zhu, Guojun. “BEC-BCS crossover with Feshbach resonance for three-hyperfine-species model.” 2012. Web. 01 Mar 2021.
Vancouver:
Zhu G. BEC-BCS crossover with Feshbach resonance for three-hyperfine-species model. [Internet] [Doctoral dissertation]. University of Illinois – Urbana-Champaign; 2012. [cited 2021 Mar 01].
Available from: http://hdl.handle.net/2142/31105.
Council of Science Editors:
Zhu G. BEC-BCS crossover with Feshbach resonance for three-hyperfine-species model. [Doctoral Dissertation]. University of Illinois – Urbana-Champaign; 2012. Available from: http://hdl.handle.net/2142/31105
Brno University of Technology
20.
Kočvara, Pavel.
Dvoupásmová stereofonní reproduktorová soustava: Two-way stereo speaker system.
Degree: 2019, Brno University of Technology
URL: http://hdl.handle.net/11012/27365
► The Bachelor thesis deals with design of a passive two-way stereo speaker system with performance 50 W RMS / 8 for normal domestic use. With…
(more)
▼ The Bachelor thesis deals with design of a passive two-way stereo speaker system with performance 50 W RMS / 8 for normal domestic use. With respect to its sensitivity 90 dB/W/m mid-range speakers Beyma 5MP50/N and tweeter Beyma T2030 were used. The enclosure is a type of bass-reflex and it is made of MDF material with internal damping from polyurethane coat.
Advisors/Committee Members: Kratochvíl, Tomáš (advisor), Polák, Ladislav (referee).
Subjects/Keywords: reproduktor; výhybka; ozvučnice; loud-speaker; crossover; enclosure
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APA (6th Edition):
Kočvara, P. (2019). Dvoupásmová stereofonní reproduktorová soustava: Two-way stereo speaker system. (Thesis). Brno University of Technology. Retrieved from http://hdl.handle.net/11012/27365
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Kočvara, Pavel. “Dvoupásmová stereofonní reproduktorová soustava: Two-way stereo speaker system.” 2019. Thesis, Brno University of Technology. Accessed March 01, 2021.
http://hdl.handle.net/11012/27365.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Kočvara, Pavel. “Dvoupásmová stereofonní reproduktorová soustava: Two-way stereo speaker system.” 2019. Web. 01 Mar 2021.
Vancouver:
Kočvara P. Dvoupásmová stereofonní reproduktorová soustava: Two-way stereo speaker system. [Internet] [Thesis]. Brno University of Technology; 2019. [cited 2021 Mar 01].
Available from: http://hdl.handle.net/11012/27365.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Kočvara P. Dvoupásmová stereofonní reproduktorová soustava: Two-way stereo speaker system. [Thesis]. Brno University of Technology; 2019. Available from: http://hdl.handle.net/11012/27365
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Brock University
21.
ACHA, ROLAND.
Ligand design for molecule-based magnetic and/or conducting materials
.
Degree: Department of Chemistry, 2013, Brock University
URL: http://hdl.handle.net/10464/4406
► Work in the area of molecule-based magnetic and/or conducting materials is presented in two projects. The first project describes the use of 4,4’-bipyridine as a…
(more)
▼ Work in the area of molecule-based magnetic and/or conducting materials is presented in two projects. The first project describes the use of 4,4’-bipyridine as a scaffold for the preparation of a new family of tetracarboxamide ligands. Four new ligands I-III have been prepared and characterized and the coordination chemistry of these ligands is presented.
This project was then extended to exploit 4,4’-bipyridine as a covalent linker between two N3O2 macrocyles. In this respect, three dimeric macrocycles have been prepared IV-VI. Substitution of the labile axial ligands of the Co(II) complex IV by [Fe(CN)6]4- afforded the self-assembly of the 1-D polymeric chain {[Co(N3O2)H2O]2Fe(CN)6}n•3H2O that has been structurally and magnetically characterized. Magnetic studies on the Fe(II) complexes V and VI indicate that they undergo incomplete spin crossover transitions in the solid state. Strategies for the preparation of chiral spin crossover N3O2 macrocycles are discussed and the synthesis of the novel chiral Fe(II) macrocyclic complex VII is reported. Magnetic susceptibility and Mössbauer studies reveal that this complex undergoes a gradual spin crossover in the solid state with no thermal hysteresis. Variable temperature X-ray diffraction studies on single crystals of VII reveal interesting structural changes in the coordination geometry of the macrocycle accompanying its SCO transition. The second project reports the synthesis and characterization of a new family of tetrathiafulvalene derivatives VIII – XII, where a heterocyclic chelating ligand is appended to a TTF donor via an imine linker.
The coordination chemistries of these ligands with M(hfac)2.H2O (M( = Co, Ni, Mn, Cu) have been explored and the structural and magnetic properties of these complexes are described.
Subjects/Keywords: Ligand design; Carboxamide; Tetrathiafulvalene; Spin crossover
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APA (6th Edition):
ACHA, R. (2013). Ligand design for molecule-based magnetic and/or conducting materials
. (Thesis). Brock University. Retrieved from http://hdl.handle.net/10464/4406
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
ACHA, ROLAND. “Ligand design for molecule-based magnetic and/or conducting materials
.” 2013. Thesis, Brock University. Accessed March 01, 2021.
http://hdl.handle.net/10464/4406.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
ACHA, ROLAND. “Ligand design for molecule-based magnetic and/or conducting materials
.” 2013. Web. 01 Mar 2021.
Vancouver:
ACHA R. Ligand design for molecule-based magnetic and/or conducting materials
. [Internet] [Thesis]. Brock University; 2013. [cited 2021 Mar 01].
Available from: http://hdl.handle.net/10464/4406.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
ACHA R. Ligand design for molecule-based magnetic and/or conducting materials
. [Thesis]. Brock University; 2013. Available from: http://hdl.handle.net/10464/4406
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
University of North Texas
22.
Shao, Jin.
Dual-band Microwave Components And Their Applications.
Degree: 2011, University of North Texas
URL: https://digital.library.unt.edu/ark:/67531/metadc103391/
► In general, Dual-Band technology enables microwave components to work at two different frequencies. This thesis introduces novel dual-band microwave components and their applications. Chapter 2…
(more)
▼ In general, Dual-Band technology enables microwave components to work at two different frequencies. This thesis introduces novel dual-band microwave components and their applications. Chapter 2 presents a novel compact dual-band balun (converting unbalanced signals to balanced ones). The ratio between two working frequencies is analyzed. A novel compact microstrip
crossover (letting two lines to cross each other with very high isolation) and its dual-band application is the
subject of chapter 3. A dual-frequency cloak based on lumped LC-circuits is introduced in chapter 4. In chapter 5, a dual-band RF device to detect dielectric constant changes of liquids in polydimethylsiloxane (PDMS) microfluidic channels has been presented. Such a device is very sensitive, and it has significantly improved the stability. Finally, conclusion of this thesis and future works are given in chapter 6.
Advisors/Committee Members: Zhang, Hualiang, Acevedo, Miguel F., Kim, Hyoung Soo.
Subjects/Keywords: Dual-band; balun; crossover; cloak; sensor
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University of Sydney
23.
Clements, John Edward.
Spin crossover and postsynthetic modification in nanoporous Hofmann-type materials
.
Degree: 2014, University of Sydney
URL: http://hdl.handle.net/2123/13714
► Herein, the Hofmann-type spin crossover (SCO) material [Fe(bipytz)(Au(CN)2)2].xEtOH (1•EtOH) where bipytz = 3,6-bis(4-pyridyl)-1,2,4,5-tetrazine and its covalent postsynthetic modification (PSM) is described. In the first instance,…
(more)
▼ Herein, the Hofmann-type spin crossover (SCO) material [Fe(bipytz)(Au(CN)2)2].xEtOH (1•EtOH) where bipytz = 3,6-bis(4-pyridyl)-1,2,4,5-tetrazine and its covalent postsynthetic modification (PSM) is described. In the first instance, structural characteristics of the as-synthesised phase 1•EtOH are investigated by variable temperature single-crystal X-ray diffraction, with follow-up SCO analysis performed with a mixture of variable temperature magnetic susceptibility, solid-state diffuse reflectance, lab- and synchroton-sourced powder X-ray diffraction. The influence of guest-exchange on 1•EtOH was also investigated, including the guest-free phase. Significant influences on the structure emerged from C–H…N and aurophilic interactions between the two-fold interpenetrated nets. Once 1•EtOH is fully described, a pre-functionalised ligand derivative 3,6-bis(4-pyridyl)-1,2,-diazine (bipydz) is used to synthesise a related Hofmann-type phase [Fe(bipydz)(Au(CN)2)2].xEtOH (2•EtOH). Similar investigation methods used for 1•EtOH are employed and reveal the first porous four-step spin crossover material, with each state identified as: HS1LS0, HS0.67LS0.33, HS0.5LS0.5, HS0.33LS0.67 and HS0LS1. Unlike 1•EtOH, 2•EtOH shows markedly different properties: it does not display negative thermal expansion, the SCO transition is nearly 100 K lower in temperature, the solvent is ordered within the pores, the chromic behaviour is drastically altered and the LIESST and reverse-LIESST effects are now observed – all from replacing two N atoms with C–H bonds. An analogous material obtained from PSM with 2,5-norbornadiene is also described, as well as phases generated from reaction with ethylene gas and pyrrole. These materials have a vastly different structural-magnetic phase transitions to 2•EtOH, with several interesting structure-function relationships established from the investigations, giving unprecedented insight into the influence of PSM on SCO.
Subjects/Keywords: spin crossover;
postsynthetic modification;
porous materials
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APA ·
Chicago ·
MLA ·
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CSE |
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APA (6th Edition):
Clements, J. E. (2014). Spin crossover and postsynthetic modification in nanoporous Hofmann-type materials
. (Thesis). University of Sydney. Retrieved from http://hdl.handle.net/2123/13714
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Clements, John Edward. “Spin crossover and postsynthetic modification in nanoporous Hofmann-type materials
.” 2014. Thesis, University of Sydney. Accessed March 01, 2021.
http://hdl.handle.net/2123/13714.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Clements, John Edward. “Spin crossover and postsynthetic modification in nanoporous Hofmann-type materials
.” 2014. Web. 01 Mar 2021.
Vancouver:
Clements JE. Spin crossover and postsynthetic modification in nanoporous Hofmann-type materials
. [Internet] [Thesis]. University of Sydney; 2014. [cited 2021 Mar 01].
Available from: http://hdl.handle.net/2123/13714.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Clements JE. Spin crossover and postsynthetic modification in nanoporous Hofmann-type materials
. [Thesis]. University of Sydney; 2014. Available from: http://hdl.handle.net/2123/13714
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
University of Cambridge
24.
Lawrence, Emma Jane.
Identifying natural modifiers of meiotic crossover frequency in Arabidopsis thaliana.
Degree: PhD, 2019, University of Cambridge
URL: https://doi.org/10.17863/CAM.36979
;
https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.767853
► During meiosis, homologous chromosomes pair and undergo reciprocal genetic exchange, producing crossovers. This generates genetic diversity and is required for balanced homolog segregation. Despite the…
(more)
▼ During meiosis, homologous chromosomes pair and undergo reciprocal genetic exchange, producing crossovers. This generates genetic diversity and is required for balanced homolog segregation. Despite the critical functions of crossovers, their frequency and distribution varies extensively within and between species. This crossover variation can be caused by trans-modifiers within populations, which encode diffusible molecules that influence crossover formation elsewhere in the genome. This project utilised natural accessions of Arabidopsis thaliana to identify trans-modifying loci underlying crossover variation within the species. I performed Quantitative Trait Loci (QTL) mapping using a fluorescence-based crossover reporter system to measure recombination frequency in a genomic interval on chromosome 3, termed 420. Mapping in a Col-420 × Bur-0 F2 population revealed four major recombination QTLs (rQTLs) that influence crossover frequency. A novel recessive rQTL on chromosome 1 that reduced crossovers within the interval was fine-mapped to a premature stop codon in TATA Binding Protein (TBP)-associated factor 4b (TAF4b) in Bur-0 (taf4b-1). TAF4b is a subunit of the TFIID complex, a multi-protein general transcription factor complex comprising TBP and numerous TAFs that forms a component of the pre-initiation complex that recruits RNA polymerase II to promoters. Transformation-based complementation experiments and the isolation of several independent taf4b alleles provided genetic proof that TAF4b is essential for wild-type levels of crossover within 420. Analysis of the prevalence of the taf4b-1 mutation in the global Arabidopsis accession collection demonstrated its specificity to three accessions in the British Isles. A combination of cytology, genetic analysis using additional fluorescent reporter lines, and sequencing in F2 recombinant populations demonstrated a genome-wide reduction in crossover frequency in taf4b-1. In addition, RNA sequencing identified numerous transcriptional changes in taf4b-1. Both up- and down-regulated gene sets displayed significant enrichment for genes that are predominantly expressed in meiocytes, and several gene ontology terms pertaining to protein modification and meiotic processes. These results further demonstrate the existence of genetic modifiers of crossover frequency in natural populations of A. thaliana, and the characterisation of a novel trans-modifier of recombination, TAF4b. This signifies a novel function for TAF4b in Arabidopsis, and further enhances our understanding of the molecular factors controlling the frequency and distribution of meiotic crossovers in plants.
Subjects/Keywords: 572.8; Arabidopsis; meiosis; recombination; crossover; variation; transcription
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APA ·
Chicago ·
MLA ·
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CSE |
Export
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APA (6th Edition):
Lawrence, E. J. (2019). Identifying natural modifiers of meiotic crossover frequency in Arabidopsis thaliana. (Doctoral Dissertation). University of Cambridge. Retrieved from https://doi.org/10.17863/CAM.36979 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.767853
Chicago Manual of Style (16th Edition):
Lawrence, Emma Jane. “Identifying natural modifiers of meiotic crossover frequency in Arabidopsis thaliana.” 2019. Doctoral Dissertation, University of Cambridge. Accessed March 01, 2021.
https://doi.org/10.17863/CAM.36979 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.767853.
MLA Handbook (7th Edition):
Lawrence, Emma Jane. “Identifying natural modifiers of meiotic crossover frequency in Arabidopsis thaliana.” 2019. Web. 01 Mar 2021.
Vancouver:
Lawrence EJ. Identifying natural modifiers of meiotic crossover frequency in Arabidopsis thaliana. [Internet] [Doctoral dissertation]. University of Cambridge; 2019. [cited 2021 Mar 01].
Available from: https://doi.org/10.17863/CAM.36979 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.767853.
Council of Science Editors:
Lawrence EJ. Identifying natural modifiers of meiotic crossover frequency in Arabidopsis thaliana. [Doctoral Dissertation]. University of Cambridge; 2019. Available from: https://doi.org/10.17863/CAM.36979 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.767853
Université Paris-Sud – Paris XI
25.
Tagliaro Jahns, Marina.
Étude du rôle de la neddylation dans la régulation de la recombinaison méiotique : Study of the role of neddylation in the regulation of meiotic recombination.
Degree: Docteur es, Biologie, 2014, Université Paris-Sud – Paris XI
URL: http://www.theses.fr/2014PA112020
► La recombinaison homologue est essentielle à la réparation des lésions de l’ADN ainsi qu’à la ségrégation correcte des chromosomes en méiose. Une étape importante de…
(more)
▼ La recombinaison homologue est essentielle à la réparation des lésions de l’ADN ainsi qu’à la ségrégation correcte des chromosomes en méiose. Une étape importante de la recombinaison méiotique est la formation des crossovers (CO). Au cours de ma thèse, j’ai mis en évidence un nouveau mécanisme de régulation de la recombinaison méiotique. J'ai montré que les cycles d'activation et de désactivation des cullin-RING ligases (CRL) sont absolument nécessaires à la recombinaison méiotique. Les CRL sont activées par neddylation et désactivées par la deneddylation. De plus, elles peuvent aussi être inhibées par la séquestration via la protéine CAND1. Mon travail a démontré que ces trois niveaux de régulation des CRL jouent des rôles cruciaux dans la recombinaison homologue méiotique chez A. thaliana. J’ai montré qu'AXR1, un composant clé de la machinerie de neddylation, est nécessaire à la localisation correcte des CO méiotiques et à la recombinaison homologue somatique. J’ai aussi prouvé que le processus de deneddylation médié par CSN5A est nécessaire à la formation des CO. J'ai obtenu des données montrant que cette régulation de la localisation des CO agit à travers la régulation d’un complexe CRL4. Enfin, j’ai pu montrer que l'inhibiteur des CRL, CAND1, est requis pour la formation de plus de 90 % des CO. En utilisant des outils génétiques et cytologiques, j'ai montré que CAND1 agit probablement sur la régulation du biais inter-homologue. L’ensemble de ces données, met l’accent sur un nouveau mécanisme de la régulation de la recombinaison homologue, connectant pour la première fois la méiose et l’ubiquitination via les cullin-RING Ligases.
Homologous recombination is essential to all living organisms in order to repair DNA damages. In addition, a large majority of organisms use homologous recombination in meiosis to ensure proper chromosome segregation. A main step of meiotic recombination is crossover (CO) formation. During my PhD, I was able to highlight a new pathway controlling meiotic recombination. I showed that cycles of activation and deactivation of cullin-RING ligases (CRLs) are absolutely required for correct meiosis. CRLs are activated by neddylation, and deactivated by deneddylation. In addition, they can also be inhibited by sequestration by the CAND1 protein. My work demonstrated that these three levels of CRL regulation play crucial roles in meiotic homologous recombination in A. thaliana. First, I showed that AXR1, a key component of the neddylation machinery, is required for the correct localisation of meiotic COs and for somatic homologous recombination. Second, I showed that the deneddylation process mediated by CSN5A is also necessary for normal CO formation. I obtained evidence that this regulation of CO position is likely to be mediated by a CRL4 complex. Last, I could show that the CRL inhibitor, CAND1, is required for the formation of up to 90% of the COs. Using genetic and cytological tools, I showed that CAND1 probably acts on the regulation of the inter-homolog bias. Considering all these…
Advisors/Committee Members: Grelon, Mathilde (thesis director).
Subjects/Keywords: Recombinaison méiotique; Crossover; Régulation des CRL; Arabidopsis thaliana; Meiotic recombination; Crossover; CRL regulation; Arabidopsis thaliana
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Tagliaro Jahns, M. (2014). Étude du rôle de la neddylation dans la régulation de la recombinaison méiotique : Study of the role of neddylation in the regulation of meiotic recombination. (Doctoral Dissertation). Université Paris-Sud – Paris XI. Retrieved from http://www.theses.fr/2014PA112020
Chicago Manual of Style (16th Edition):
Tagliaro Jahns, Marina. “Étude du rôle de la neddylation dans la régulation de la recombinaison méiotique : Study of the role of neddylation in the regulation of meiotic recombination.” 2014. Doctoral Dissertation, Université Paris-Sud – Paris XI. Accessed March 01, 2021.
http://www.theses.fr/2014PA112020.
MLA Handbook (7th Edition):
Tagliaro Jahns, Marina. “Étude du rôle de la neddylation dans la régulation de la recombinaison méiotique : Study of the role of neddylation in the regulation of meiotic recombination.” 2014. Web. 01 Mar 2021.
Vancouver:
Tagliaro Jahns M. Étude du rôle de la neddylation dans la régulation de la recombinaison méiotique : Study of the role of neddylation in the regulation of meiotic recombination. [Internet] [Doctoral dissertation]. Université Paris-Sud – Paris XI; 2014. [cited 2021 Mar 01].
Available from: http://www.theses.fr/2014PA112020.
Council of Science Editors:
Tagliaro Jahns M. Étude du rôle de la neddylation dans la régulation de la recombinaison méiotique : Study of the role of neddylation in the regulation of meiotic recombination. [Doctoral Dissertation]. Université Paris-Sud – Paris XI; 2014. Available from: http://www.theses.fr/2014PA112020
Kaunas University of Technology
26.
Katkus,
Kęstutis.
Hibridinis genetinis algoritmas komivojažieriaus
uždaviniui.
Degree: Master, Informatics, 2006, Kaunas University of Technology
URL: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2006~D_20060606_203011-23232
;
► In this work, the Traveling Salesman Problem (TSP) is discussed. The Hybrid Genetic Algorithm for solving the TSP is presented. The traveling salesman problem is…
(more)
▼ In this work, the Traveling Salesman Problem
(TSP) is discussed. The Hybrid Genetic Algorithm for solving the
TSP is presented. The traveling salesman problem is formulated as
follows: given matrix D=(dij)nxn of distances between n objects and
the set P of permutations of the integers from 1 to n, find a
permutation p=(p(1), p(2), ..., p(n)) P that minimizes. Many
heuristic algorithms can be applied for the TSP. Recently, genetic
algorithms (GAs) are among the advanced heuristic techniques for
the combinatorial problems, like the TSP. genetic algorithms are
based on the biological process of natural selection. The original
concepts of GAs were developed in 1970s. Many simulations have
demonstrated the efficiency of GAs on different optimization
problems, among them, bin–packing, generalized assignment problem,
graph partitioning, job–shop scheduling problem, set covering
problem, vehicle routing. One of the main operators in GAs is the
crossover (i.e. solution recombination). This operator plays a very
important role by constructing competitive GAs. In this work, we
investigate several
crossover operators for the TSP, among them, CX
(cycle
crossover), PMX (partialy mapped
crossover), POS (position
based
crossover), ER (edge recombination
crossover), edge-NN (edge
recombination
crossover, nearest neighbour) and AP
(alternating-positions
crossover). Comparison of these
crossover
operators was performed. The results show high efficiency of the
edge-NN, ER and PMX crossovers.
Advisors/Committee Members: Plėštys, Rimantas (Master’s degree committee member), Misevičius, Alfonsas (Master’s thesis supervisor), Barauskas, Rimantas (Master’s degree committee member), Mockus, Jonas (Master’s degree committee member), Jasinevičius, Raimundas (Master’s degree committee member), Telksnys, Laimutis (Master’s degree committee chair), Pranevičius, Henrikas (Master’s degree committee member), Maciulevičius, Stasys (Master’s degree session secretary), Jusas, Vacius (Master’s thesis reviewer).
Subjects/Keywords: Genetinis algoritmas; Alternating-positions
crossover; Edge-NN; Partialy mapped crossover; Edge recombination crossover; TSP; Komivojažieriaus uždavinys; Cycle crossover; Position based crossover
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APA ·
Chicago ·
MLA ·
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Export
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APA (6th Edition):
Katkus,
Kęstutis. (2006). Hibridinis genetinis algoritmas komivojažieriaus
uždaviniui. (Masters Thesis). Kaunas University of Technology. Retrieved from http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2006~D_20060606_203011-23232 ;
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
Chicago Manual of Style (16th Edition):
Katkus,
Kęstutis. “Hibridinis genetinis algoritmas komivojažieriaus
uždaviniui.” 2006. Masters Thesis, Kaunas University of Technology. Accessed March 01, 2021.
http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2006~D_20060606_203011-23232 ;.
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
MLA Handbook (7th Edition):
Katkus,
Kęstutis. “Hibridinis genetinis algoritmas komivojažieriaus
uždaviniui.” 2006. Web. 01 Mar 2021.
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
Vancouver:
Katkus,
Kęstutis. Hibridinis genetinis algoritmas komivojažieriaus
uždaviniui. [Internet] [Masters thesis]. Kaunas University of Technology; 2006. [cited 2021 Mar 01].
Available from: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2006~D_20060606_203011-23232 ;.
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
Council of Science Editors:
Katkus,
Kęstutis. Hibridinis genetinis algoritmas komivojažieriaus
uždaviniui. [Masters Thesis]. Kaunas University of Technology; 2006. Available from: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2006~D_20060606_203011-23232 ;
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
Johannes Gutenberg Universität Mainz
27.
Oberhaus, Johanna.
Modellkomplexe oligonuklearer Metalloproteine auf Basis von Salen-Liganden und Spin-Crossover-Verbindungen als Chemosensoren.
Degree: 2013, Johannes Gutenberg Universität Mainz
URL: http://ubm.opus.hbz-nrw.de/volltexte/2015/4098/
► Der erste Teil der hier vorgestellten Arbeit verfolgt die Synthese potentieller Modellverbindungen oligonuklearer Metalloproteine auf Basis von Salen-Liganden. Dazu wurden zwei Ligandensysteme mit unterschiedlich raumerfüllenden…
(more)
▼ Der erste Teil der hier vorgestellten Arbeit verfolgt die Synthese potentieller Modellverbindungen oligonuklearer Metalloproteine auf Basis von Salen-Liganden. Dazu wurden zwei Ligandensysteme mit unterschiedlich raumerfüllenden Alkyl-Substituenten modifiziert und auf ihre koordinativen Eigenschaften hin untersucht. Für das Ligandensystem auf Basis des Bis-(salicylidenamino)-propan-2-ols konnten fünf Derivate (H3L1, H3L2A,H3L2B, H3L3, H3L4), für das zweite verwendete Ligandensystem auf Basis des 1H-3,5-Bis-(salicylidenaminomethyl)-pyrazols konnten zwei weitere Derivate (H3L5A, H3L5B) dargestellt und zu Koordinationsverbindungen umgesetzt werden.rnFür den hier verwendeten Bis-(salicylidenamino)-propan-2-ol Liganden H3L1, welcher die geringsten sterischen Anforderungen stellt, konnten mono-, tri- und tetranukleare Koordinationsverbindungen synthetisiert werden. Dabei gelingt es dem Liganden, sich sowohl in planarer als auch in unterschiedlich stark gewinkelter Konformation um ein oder mehrere Metallzentren anzuordnen, wobei der Ligand ein N2O2- seines N2O3-Donorsets zur Koordination nutzt. Die Verbindung {[Ni7(HL1)2(L1)2(OBz)4(OMe)(H2O)]}n zeigt, dass eine Verkettung der so gestalteten dreikernigen Einheiten über das freie Propanol-Sauerstoffatomdes Ligandenrückgrats möglich ist. Mit zunehmendem sterischen Anspruch der angefügten Alkylsubstituenten nimmt die geometrische Flexibilität und somit das Potential des Liganden zur Ausbildung höhernuklearer Strukturen ab. So ist für Liganden mit mittlerem sterischen Anspruch neben mononuklearen Komplexen noch die Gestaltung dinuklearer Systeme möglich. Erhöht man den sterischen Anspruch des Liganden weiter, findet nur noch eine Reaktion zu mononuklearen Verbindungen statt.rnMit den Pyrazol-basierten Ligandensystemen H3L5A und H3L5B konnten dinukleare Kupfer- und Nickelverbindungen synthetisiert werden.rnDer zweite Teil dieser Arbeit befasst sich mit der Gestaltung von Spin-Crossover Systemen (SCO). Dazu soll ein Spinübergang innerhalb des gestalteten schaltbaren Systems an die Anwesenheit eines Signalstoffs gekoppelt werden, so dass diese SCO-Verbindung als Sensor für den Signalstoff eingesetzt werden kann. Dazu wurden zwei unterschiedliche Ansätze entwickelt und untersucht.rnDie erste Methode beruht auf der Kombination eines zum Spin-Crossover befähigten Metallzentrums, eines Capping-Liganden, eines zur Signalstofferkennung funktionalisierten Co-Liganden sowie eines entsprechenden Signalstoffs. Als Capping-Liganden wurden tetra- und pentadentateLigandensysteme eingesetzt und mit unterschiedlich Picolyl-substituierten Monoaza-[12]-krone-4-Derivaten umgesetzt, wobei die Monoazakrone zur Komplexierung des Signalstoffs,hier in Form eines Alkalimetallions, zur Verfügung steht. Nach dieser ersten Methode konnten im Zeitraum dieser Arbeit noch keine zufriedenstellenden Ergebnisse erzielt werden.rnEine vielversprechende zweite Möglichkeit beruht auf der Verwendung eines mehrzähnigen, etablierten Spin-Crossover Liganden,welcher in seiner Peripherie mit einer Bindungstasche zur…
Subjects/Keywords: Modellkomplexe; Metalloproteine; Spinn-Crossover; Terpyridin; Salen; model complex; metalloprotein; spin crossover; terpyridine; salene; Chemistry and allied sciences
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Record Details
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Oberhaus, J. (2013). Modellkomplexe oligonuklearer Metalloproteine auf Basis von Salen-Liganden und Spin-Crossover-Verbindungen als Chemosensoren. (Doctoral Dissertation). Johannes Gutenberg Universität Mainz. Retrieved from http://ubm.opus.hbz-nrw.de/volltexte/2015/4098/
Chicago Manual of Style (16th Edition):
Oberhaus, Johanna. “Modellkomplexe oligonuklearer Metalloproteine auf Basis von Salen-Liganden und Spin-Crossover-Verbindungen als Chemosensoren.” 2013. Doctoral Dissertation, Johannes Gutenberg Universität Mainz. Accessed March 01, 2021.
http://ubm.opus.hbz-nrw.de/volltexte/2015/4098/.
MLA Handbook (7th Edition):
Oberhaus, Johanna. “Modellkomplexe oligonuklearer Metalloproteine auf Basis von Salen-Liganden und Spin-Crossover-Verbindungen als Chemosensoren.” 2013. Web. 01 Mar 2021.
Vancouver:
Oberhaus J. Modellkomplexe oligonuklearer Metalloproteine auf Basis von Salen-Liganden und Spin-Crossover-Verbindungen als Chemosensoren. [Internet] [Doctoral dissertation]. Johannes Gutenberg Universität Mainz; 2013. [cited 2021 Mar 01].
Available from: http://ubm.opus.hbz-nrw.de/volltexte/2015/4098/.
Council of Science Editors:
Oberhaus J. Modellkomplexe oligonuklearer Metalloproteine auf Basis von Salen-Liganden und Spin-Crossover-Verbindungen als Chemosensoren. [Doctoral Dissertation]. Johannes Gutenberg Universität Mainz; 2013. Available from: http://ubm.opus.hbz-nrw.de/volltexte/2015/4098/
Mississippi State University
28.
Seneviratne, Jehan Amila.
Phasor-based study of electromagnetic scattering by small particles.
Degree: PhD, Physics and Astronomy, 2018, Mississippi State University
URL: http://sun.library.msstate.edu/ETD-db/theses/available/etd-03022018-094151/
;
► When scattering intensity is plotted against the dimensionless quantity qR, where q is the magnitude of the scattering wave vector and R is the…
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▼ When scattering intensity is plotted against the dimensionless quantity qR, where q is the magnitude of the scattering wave vector and R is the radius of the particle, in log-log scale the scattering curve shows a power-law structure which defines characteristic crossovers. This work reveals some new relationships between the power-law structure and the particle properties. In this work, computer simulation results from T-matrix, Mie theory, and discrete dipole approximation methods are used to study the far field intensity and the internal field of the particles.
Scattering by both weakly and strongly refractive particles are studied.
For weakly refractive randomly oriented spheroidal particles, how the phasor cancellation-based tip volume method can be applied to predict the scattering envelope is demonstrated. The relationship between backscattering enhancement and the curvature of the weakly refractive particles is explained.
In strongly-refractive particles when the phase shift parameter is high, regions with higher field amplitudes start to appear. These regions are recognized as the hot spot regions. In this work, a proper definition is given to the hot spot region. The relationships between the hot spot region and the power-law structure, between the hot spot region and the particle morphology, and between the power-law structure and the particle morphology are extensively studied for scattering by spherical particles.
A new semi-quantitative phasor analysis method is introduced, and the new method is used with color-coded phasor plots to identify how different regions of the particle contribute to the scattering pattern to get an insight into the physics behind the scattering. How different regions of the particle contribute to the second
crossover (SC) and the backscattering enhancement is presented.
Relationships between the SC, particle size, and relative refractive index of the particle are derived. It was identified that the scattering angle at the SC depends only on the relative refractive index of the particle.
How the findings of this work can be applied to solve the inverse electromagnetic scattering problem for a single non-absorbing spherical particle is also discussed.
Advisors/Committee Members: Matthew J. Berg (chair), R. Torsten Clay (committee member), Chuji Wang (committee member), Yaroslav Koshka (committee member), Hendrik F. Arnoldus (committee member).
Subjects/Keywords: small particle; Guinier crossover; second crossover; size parameter; light scattering; particle charaterization; q-space analysis; inverse problem; far-field
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APA (6th Edition):
Seneviratne, J. A. (2018). Phasor-based study of electromagnetic scattering by small particles. (Doctoral Dissertation). Mississippi State University. Retrieved from http://sun.library.msstate.edu/ETD-db/theses/available/etd-03022018-094151/ ;
Chicago Manual of Style (16th Edition):
Seneviratne, Jehan Amila. “Phasor-based study of electromagnetic scattering by small particles.” 2018. Doctoral Dissertation, Mississippi State University. Accessed March 01, 2021.
http://sun.library.msstate.edu/ETD-db/theses/available/etd-03022018-094151/ ;.
MLA Handbook (7th Edition):
Seneviratne, Jehan Amila. “Phasor-based study of electromagnetic scattering by small particles.” 2018. Web. 01 Mar 2021.
Vancouver:
Seneviratne JA. Phasor-based study of electromagnetic scattering by small particles. [Internet] [Doctoral dissertation]. Mississippi State University; 2018. [cited 2021 Mar 01].
Available from: http://sun.library.msstate.edu/ETD-db/theses/available/etd-03022018-094151/ ;.
Council of Science Editors:
Seneviratne JA. Phasor-based study of electromagnetic scattering by small particles. [Doctoral Dissertation]. Mississippi State University; 2018. Available from: http://sun.library.msstate.edu/ETD-db/theses/available/etd-03022018-094151/ ;
29.
Marinho, Vera Lúcia da Silva.
Estudo do efeito crossover de metanol na reação de redução de oxigênio em células a combustível.
Degree: 2010, Universidade Federal do Amazonas
URL: http://tede.ufam.edu.br/handle/tede/3334
► As células a combustível de metanol direto são fontes alternativas de energia para dar suporte principalmente às baterias. A sociedade científica vem nas últimas décadas…
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▼ As células a combustível de metanol direto são fontes alternativas de energia para dar suporte principalmente às baterias. A sociedade científica vem nas últimas décadas realizando experimentos para superação das barreiras técnicas que impedem sua comercialização. O efeito crossover de metanol, do anodo para o cátodo através da membrana, é um problema muito sério que reduz severamente o potencial da célula, a densidade de corrente, a utilização de combustível e, portanto o desempenho da célula. O objetivo deste trabalho é compreender melhor o efeito crossover de metanol neste tipo de tecnologia e tentar minimizar os efeitos negativos melhorando a eficiência da célula a combustível. Para isso foram preparados eletrocatalisadores de Pt com a impregnação de um segundo metal tanto para o ânodo como para o cátodo usando três diferentes métodos: redução por álcool (MRA), etilenoglicol (MRE) e ácido fórmico (MAF) como agentes redutores. A fabricação dos eletrodos seguiu a técnica de pintura e o eletrólito empregado foi a membrana de Nafion 117. Para a caracterização física dos eletrocatalisadores modificados, amostras foram submetidos às técnicas de energia dispersiva de raio-x e difração de raios-X. O grau de crossover de metanol através da membrana foi investigado durante os testes eletroquímicos dos eletrodos modificados de PtMo/C, ânodo, e PtCo/C e PtNi/C, cátodo, por meio de curvas de polarização realizados na célula unitária. Os resultados mostraram que o método de redução por álcool é o melhor para impregnação da platina, porém a liga formada por este metal possui atividade catalítica ineficiente para oxidação do metanol o que conduz a elevado efeito crossover de metanol e consequentemente desempenho eletroquímico reduzido. Os eletrodos de PtCo/C e PtNi/C modificados tiveram resultados aproximados aos comerciais e mostram-se eficientes para redução do oxigênio e tolerantes a oxidação de metanol. Assim, podemos afirmar que minimizando os efeitos do crossover de metanol sob o desempenho eletroquímico podemos obter células de metanol direto eficientes e capazes de dar suporte às baterias .
The direct methanol fuel cells are powers alternatives of energy to do support mainly the batteries. The scientific society come in last decades realizing experiments to overcome the technical barriers that block her commercialization. The effect of methanol crossover, from the anode to the cathode through the membrane, is a very serious problem that that severely reduces the cell voltage, current density, fuel utilization and hence the cell performance. The aim this work is better understand the effect of methanol crossover in this type of technology e try to minimize his negative effects improving the efficiency of fuel cell. To this were prepared electrocatalyts of Pt with an second metal so much in anode as us in cathode using three differents methods: alcohol reduction (MRA), ethylene glycol (MRE) and formic acid (MAF) as reducing agents. The electrodes were prepared following technical of the literature, membrane and…
Advisors/Committee Members: Passos, Raimundo Ribeiro, CPF:47357614387, http://lattes.cnpq.br/2022301821222852.
Subjects/Keywords: Células de metanol; Efeito crossover; Desempenho elétrico; Fuel cells; Effect crossover; Electrochemical performance; CIÊNCIAS EXATAS E DA TERRA: QUÍMICA
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APA ·
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APA (6th Edition):
Marinho, V. L. d. S. (2010). Estudo do efeito crossover de metanol na reação de redução de oxigênio em células a combustível. (Masters Thesis). Universidade Federal do Amazonas. Retrieved from http://tede.ufam.edu.br/handle/tede/3334
Chicago Manual of Style (16th Edition):
Marinho, Vera Lúcia da Silva. “Estudo do efeito crossover de metanol na reação de redução de oxigênio em células a combustível.” 2010. Masters Thesis, Universidade Federal do Amazonas. Accessed March 01, 2021.
http://tede.ufam.edu.br/handle/tede/3334.
MLA Handbook (7th Edition):
Marinho, Vera Lúcia da Silva. “Estudo do efeito crossover de metanol na reação de redução de oxigênio em células a combustível.” 2010. Web. 01 Mar 2021.
Vancouver:
Marinho VLdS. Estudo do efeito crossover de metanol na reação de redução de oxigênio em células a combustível. [Internet] [Masters thesis]. Universidade Federal do Amazonas; 2010. [cited 2021 Mar 01].
Available from: http://tede.ufam.edu.br/handle/tede/3334.
Council of Science Editors:
Marinho VLdS. Estudo do efeito crossover de metanol na reação de redução de oxigênio em células a combustível. [Masters Thesis]. Universidade Federal do Amazonas; 2010. Available from: http://tede.ufam.edu.br/handle/tede/3334
30.
Gault, Nathalie.
Plans expérimentaux de type self-controlled en pharmacoépidémiologie : Self-controlled designs in pharmacoepidemiology.
Degree: Docteur es, Epidémiologie et sciences de l’information biomédicale, 2017, Sorbonne Paris Cité
URL: http://www.theses.fr/2017USPCC115
► Les études de pharmacoépidémiologie consistent à étudier l’effet de médicaments en vie réelle, et sont menées de plus en plus souvent sur bases de données…
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▼ Les études de pharmacoépidémiologie consistent à étudier l’effet de médicaments en vie réelle, et sont menées de plus en plus souvent sur bases de données médico-administratives. Ce sont principalement des études observationnelles, et sont donc soumises à des biais liés à des facteurs de confusion. Ces facteurs ne sont pas toujours recueillis dans les bases de données médico-administratives qui sont implémentées à d’autres fins que la recherche. Des plans expérimentaux self-controlled designs (où le patient est son propre témoin, et dont les principaux sont le case-crossover et le self-controlled case-series) permettent d’étudier l’effet transitoire d'expositions brèves sur des évènements à début brutal. Ils sont soumis à certaines conditions d’application. Ils ont la particularité de réaliser des comparaisons sur différentes périodes plutôt que sur différents groupes de patients, permettant ainsi de prendre en compte des facteurs de confusion, y compris non mesurés, et qui ne varient pas entre les périodes observées. Ces méthodes ont montré leur utilité pour pallier l’absence de randomisation, et leur utilisation est recommandée quand leurs conditions d’application sont remplies. Nous avons étudié la fréquence d’utilisation des self-controlled designs en pharmacoépidémiologie sur bases de données, les opportunités manquées d’utilisation et leur usage approprié au regard de leurs conditions d’application, ainsi que la qualité de l’information rapportée dans les articles. Nous avons montré que leur utilisation est rare, que 15% des articles correspondent à des situations d’opportunité où ces méthodes auraient pu être implémentées, que 34% des case-crossover et 13% des self-controlled case-series étaient appliqué de façon inapproprié, et que pour 16% des articles la méthode aurait pu être adaptée pour être valide. Un usage plus approprié permettrait de contribuer à l’investigation en pharmacoépidémiologie tout en bénéficiant des avantages de ces méthodes en particulier sur bases de données de santé.
Pharmacoepidemiology consists in the study of efficacy or safety of drugs in real life, with the use more and more frequently of medico-administrative databases. Study designs are generally observational, thus they are prone to confounding bias. Confounders are not systematically collected in databases, which are implemented for other purposes than research. Self-controlled designs (mainly represented by case-crossover and self-controlled case-series, and in which the patient acts as his own control), have been developed for the study of intermittent exposure with short-term effect on abrupt onset event. They require that validity assumptions being fulfilled. They consist in the comparison over different periods, rather than different groups of patients, thus allowing for confounding factors, also if not measured, which are invariant over observed periods. Such designs have been proved useful in observational studies in the absence of randomization, and their implementation is recommended in case of validity assumptions…
Advisors/Committee Members: Tubach, Florence (thesis director).
Subjects/Keywords: Self-controlled case series; Case-crossover; Self-controlled case series; Case-crossover; Observational studies; Confusion bias
Record Details
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Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Gault, N. (2017). Plans expérimentaux de type self-controlled en pharmacoépidémiologie : Self-controlled designs in pharmacoepidemiology. (Doctoral Dissertation). Sorbonne Paris Cité. Retrieved from http://www.theses.fr/2017USPCC115
Chicago Manual of Style (16th Edition):
Gault, Nathalie. “Plans expérimentaux de type self-controlled en pharmacoépidémiologie : Self-controlled designs in pharmacoepidemiology.” 2017. Doctoral Dissertation, Sorbonne Paris Cité. Accessed March 01, 2021.
http://www.theses.fr/2017USPCC115.
MLA Handbook (7th Edition):
Gault, Nathalie. “Plans expérimentaux de type self-controlled en pharmacoépidémiologie : Self-controlled designs in pharmacoepidemiology.” 2017. Web. 01 Mar 2021.
Vancouver:
Gault N. Plans expérimentaux de type self-controlled en pharmacoépidémiologie : Self-controlled designs in pharmacoepidemiology. [Internet] [Doctoral dissertation]. Sorbonne Paris Cité; 2017. [cited 2021 Mar 01].
Available from: http://www.theses.fr/2017USPCC115.
Council of Science Editors:
Gault N. Plans expérimentaux de type self-controlled en pharmacoépidémiologie : Self-controlled designs in pharmacoepidemiology. [Doctoral Dissertation]. Sorbonne Paris Cité; 2017. Available from: http://www.theses.fr/2017USPCC115
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