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University of KwaZulu-Natal
1.
Omodan, Abiola Olugbenga.
Anatomical classification of Tessier craniofacial clefts number 3 and number 4 in a South African population.
Degree: 2019, University of KwaZulu-Natal
URL: https://researchspace.ukzn.ac.za/handle/10413/18601
► The craniofacial clefts are rare defects of the face with an incidence of 1.43 to 4.85 per 100,000 live births. In 2016, WHO reported a…
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▼ The
craniofacial clefts are rare defects of the face with an incidence of 1.43 to 4.85 per 100,000 live births. In 2016, WHO reported a death rate of 303,000 new-borns before 4 weeks of age due to congenital anomalies of which
craniofacial clefts are one. Surviving the defect is associated with long term disabilities which impacts the individual, families, the healthcare system and society. How much we know about these clefts is seriously hampered by the rarity and the variations of these defects, so much so, that its treatment and communication amongst researchers is affected. The understanding of the skeletal defects occurring in the clefts has long been postulated as a key to any successive reconstruction of the face. This study aimed to reveal the extent of our understanding of these clefts, document the anatomical basis for the
craniofacial cleft number 3 and number 4 and generating a sub-classification based on this and also document the clinical presentation as well as associated clefts of these
craniofacial clefts in our select South African population.
The methods used to achieve these included conducting a scoping review of the literature on patients with Tessier cleft number 3 and number 4 using relevant identified studies from 1976 sourced from PubMed, Medline, EBSCOhost, Google Scholar and the Cochrane libraries. The result of the study was reported using the Preferred Reporting Items for Systematic and Meta-analyses (PRISMA). Likewise, CT scans of patients who had been treated for Tessier clefts number 3 and 4 at Inkosi Albert Luthuli Central Hospital in Durban South Africa between 2003 and 2017 were analysed. Measurements of the expected defects in each cleft were taken and compared with the unaffected side as reference points. Emerging patterns of their analysis were then used to generate a sub-classification for these clefts. Lastly the records of 8 patients who had been treated for either Tessier cleft number 3 or number 4 were reviewed and compared with 9 studies sourced from the literature. In addition to the defects recorded, associated clefts and other congenital malformations were also documented, and findings were compared.
The scoping review had 33 studies that met the inclusion criteria. The majority were conducted in middle income countries (54.5%) while none were recorded in low income countries. Only 12.1% of the included studies reported on anthropometry. In understanding the skeletal defects, the presence of an alveolar cleft, the emerging patterns of comparison of the measurements of the maxilla and the orbits of the cleft side and the non-cleft side as well as absence of the bone were used to arrive at a sub-classification system using (a), (b). (c), (M+ O+), (M- O-), and (0). Clinical presentation of the patients who had been treated as cases of Tessier cleft number 3 and number 4 were compared to the reviewed literature and the different parameters were documented. In addition, associated clefts were also recorded, and this study found that the association pattern noted for…
Advisors/Committee Members: Madaree, Anil. (advisor), Lazarus, Lelika. (advisor), Pillay, Pamela. (advisor), Satyapal, Kapil Sewsaran. (advisor).
Subjects/Keywords: Tessier craniofacial clefts.; Congenital craniofacial cleft.; Labial commissure.; Tessier classification system.; Craniofacial tissues.; Congenital anomalies.
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APA (6th Edition):
Omodan, A. O. (2019). Anatomical classification of Tessier craniofacial clefts number 3 and number 4 in a South African population. (Thesis). University of KwaZulu-Natal. Retrieved from https://researchspace.ukzn.ac.za/handle/10413/18601
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Omodan, Abiola Olugbenga. “Anatomical classification of Tessier craniofacial clefts number 3 and number 4 in a South African population.” 2019. Thesis, University of KwaZulu-Natal. Accessed March 05, 2021.
https://researchspace.ukzn.ac.za/handle/10413/18601.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Omodan, Abiola Olugbenga. “Anatomical classification of Tessier craniofacial clefts number 3 and number 4 in a South African population.” 2019. Web. 05 Mar 2021.
Vancouver:
Omodan AO. Anatomical classification of Tessier craniofacial clefts number 3 and number 4 in a South African population. [Internet] [Thesis]. University of KwaZulu-Natal; 2019. [cited 2021 Mar 05].
Available from: https://researchspace.ukzn.ac.za/handle/10413/18601.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Omodan AO. Anatomical classification of Tessier craniofacial clefts number 3 and number 4 in a South African population. [Thesis]. University of KwaZulu-Natal; 2019. Available from: https://researchspace.ukzn.ac.za/handle/10413/18601
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
2.
Ahsan, Salahuddin Mohammad Ali.
Craniofacial cephalometric analysis of Bangladeshi and Japanese adults with normal occlusion and balanced faces : A comparative study : 正常咬合者および調和のとれた顔網を持つ、バングラデシュ成人と日本人成人とにおけるセファログラム分析を用いた顎顔面形態の比較研究.
Degree: 博士(歯学), 2013, Niigata University / 新潟大学
URL: http://hdl.handle.net/10191/24559
► 学位の種類: 博士(歯学). 報告番号: 甲第3819号. 学位記番号: 新大院博(歯)甲第285号. 学位授与年月日: 平成25年9月20日
Journal of Orthodontic Science. 2013, 2(1), 7-15
Aims: To determine the cephalometric norm among Bangladeshi adults and…
(more)
▼ 学位の種類: 博士(歯学). 報告番号: 甲第3819号. 学位記番号: 新大院博(歯)甲第285号. 学位授与年月日: 平成25年9月20日
Journal of Orthodontic Science. 2013, 2(1), 7-15
Aims: To determine the cephalometric norm among Bangladeshi adults and to investigate the differences in craniofacial morphology compared with Japanese and Caucasian normative data. Materials and Methods: Cephalometric radiographs were obtained from 46 Bangladeshi males (mean age 23.8 years) and 52 Bangladeshi females (mean age 24.6 years). Inclusion criteria were the following: Both parents from the same ethnic group, class-I occlusion with an arch length discrepancy less than 2 mm, overbite and overjet from 2 to 4 mm, balanced face, all teeth present except third molar, no previous orthodontic treatment, and no prosthetic replacement of teeth. Nine angular and five linear measurements were constructed for skeletal hard tissue analysis, four angular and six linear measurements for dental hard tissue analysis, and two angular and seven linear measurements for soft tissue analysis. Mean and standard deviations of measurements were determined for each gender. Polygonal chart and profilogram were made. Independent t-test was used to determine differences. Results: The present Bangladeshi population has a smaller lower face height ( P<0.01) and the antero-posterior position of the maxilla and mandible was found to be significantly ( P<0.01) more protruded compared with the Japanese and the Caucasian norms. Significantly ( P<0.01) more protruded upper incisor, less steep occlusal plane, and thinner soft tissue chin were the characteristics in Bangladeshi adults. Conclusions: Relative to the cranial base (SN), the maxillo-mandibular complex was more anteriorly placed compared with the Japanese and Caucasian adults. Further, the effective length of the maxilla and mandible was shorter compared with the Japanese and Caucasian adults. These findings should be considered carefully during orthodontic treatment planning of Bangladeshi adults.
Subjects/Keywords: Bangladeshi; cephalometry; craniofacial structures; Japanese
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
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APA (6th Edition):
Ahsan, S. M. A. (2013). Craniofacial cephalometric analysis of Bangladeshi and Japanese adults with normal occlusion and balanced faces : A comparative study : 正常咬合者および調和のとれた顔網を持つ、バングラデシュ成人と日本人成人とにおけるセファログラム分析を用いた顎顔面形態の比較研究. (Thesis). Niigata University / 新潟大学. Retrieved from http://hdl.handle.net/10191/24559
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Ahsan, Salahuddin Mohammad Ali. “Craniofacial cephalometric analysis of Bangladeshi and Japanese adults with normal occlusion and balanced faces : A comparative study : 正常咬合者および調和のとれた顔網を持つ、バングラデシュ成人と日本人成人とにおけるセファログラム分析を用いた顎顔面形態の比較研究.” 2013. Thesis, Niigata University / 新潟大学. Accessed March 05, 2021.
http://hdl.handle.net/10191/24559.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Ahsan, Salahuddin Mohammad Ali. “Craniofacial cephalometric analysis of Bangladeshi and Japanese adults with normal occlusion and balanced faces : A comparative study : 正常咬合者および調和のとれた顔網を持つ、バングラデシュ成人と日本人成人とにおけるセファログラム分析を用いた顎顔面形態の比較研究.” 2013. Web. 05 Mar 2021.
Vancouver:
Ahsan SMA. Craniofacial cephalometric analysis of Bangladeshi and Japanese adults with normal occlusion and balanced faces : A comparative study : 正常咬合者および調和のとれた顔網を持つ、バングラデシュ成人と日本人成人とにおけるセファログラム分析を用いた顎顔面形態の比較研究. [Internet] [Thesis]. Niigata University / 新潟大学; 2013. [cited 2021 Mar 05].
Available from: http://hdl.handle.net/10191/24559.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Ahsan SMA. Craniofacial cephalometric analysis of Bangladeshi and Japanese adults with normal occlusion and balanced faces : A comparative study : 正常咬合者および調和のとれた顔網を持つ、バングラデシュ成人と日本人成人とにおけるセファログラム分析を用いた顎顔面形態の比較研究. [Thesis]. Niigata University / 新潟大学; 2013. Available from: http://hdl.handle.net/10191/24559
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Michigan
3.
Hsieh, Yuan-Lynn.
The Effect of Tsc1 Deletion on Craniofacial Bone Development.
Degree: MS, Prosthodontics, 2019, University of Michigan
URL: http://hdl.handle.net/2027.42/150098
► Cranial base is important to the development of craniofacial skeleton since it is connected to face and cranial vault, functioning as a supporting platform of…
(more)
▼ Cranial base is important to the development of
craniofacial skeleton since it is connected to face and cranial vault, functioning as a supporting platform of brain and foundation structure of skull. Developmental defects in the cranial base may lead to clinical symptoms such as midfacial hypoplasia. Synchondroses in the cranial base, including ISS (intersphenoid synchondrosis) and SOS (spheno-occipital synchondrosis), are growth centers and critical to the development of cranial facial bone. The aim of this study is to determine the effect of Tsc1 deletion in chondrocytes on the
craniofacial bone development. The part I pilot study showed that the CKOP0-Cre, CKOCol2a1-Cre and CKOATC-Cre mice had disrupted skull development with varied severity and distinct changes in synchondroses. The difference in phenotypes suggested different roles of Tsc1 gene at different differentiation stages of chondrocyte. The part II study focused on the Col2a1-Cre model. Tsc1 deletion by Col2a1-Cre led to skull defects in mice including a decrease in the length of cranial base; a decrease in facial width and height; and rounder cranial cavity. Besides morphological change, both ISS and SOS were significantly expanded in the CKOCol2a1-Cre mice, primarily by increased cell number and size in the resting zone. We present a model to conclude the study that upregulated mTORC1 activity led to abnormally high expression of IHH and PTHrP-r in resting zone chondrocytes, which may lead to the premature differentiation and the failure to transition into proliferative zone, resulting in the accumulation of cells in the resting zone with consequent expansion of the resting zone.
Advisors/Committee Members: Liu (advisor), Mishina, Yuji (committee member), Mendonça, Deniela (committee member), Zhang, Honghao (committee member).
Subjects/Keywords: Craniofacial Bone Development; Tsc1
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Hsieh, Y. (2019). The Effect of Tsc1 Deletion on Craniofacial Bone Development. (Masters Thesis). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/150098
Chicago Manual of Style (16th Edition):
Hsieh, Yuan-Lynn. “The Effect of Tsc1 Deletion on Craniofacial Bone Development.” 2019. Masters Thesis, University of Michigan. Accessed March 05, 2021.
http://hdl.handle.net/2027.42/150098.
MLA Handbook (7th Edition):
Hsieh, Yuan-Lynn. “The Effect of Tsc1 Deletion on Craniofacial Bone Development.” 2019. Web. 05 Mar 2021.
Vancouver:
Hsieh Y. The Effect of Tsc1 Deletion on Craniofacial Bone Development. [Internet] [Masters thesis]. University of Michigan; 2019. [cited 2021 Mar 05].
Available from: http://hdl.handle.net/2027.42/150098.
Council of Science Editors:
Hsieh Y. The Effect of Tsc1 Deletion on Craniofacial Bone Development. [Masters Thesis]. University of Michigan; 2019. Available from: http://hdl.handle.net/2027.42/150098
4.
서, 승조.
Is craniofacial asymmetry progressive in the untreated congenital muscular torticollis?.
Degree: 2012, Ajou University
URL: http://repository.ajou.ac.kr/handle/201003/7601
;
http://dcoll.ajou.ac.kr:9080/dcollection/jsp/common/DcLoOrgPer.jsp?sItemId=000000012967
► Although craniofacial asymmetry is frequently involved in the congenital muscular torticollis (CMT) patients who require surgical release, it has not been evaluated appropriately. Therefore, little…
(more)
▼ Although craniofacial asymmetry is frequently involved in the congenital muscular torticollis (CMT) patients who require surgical release, it has not been evaluated appropriately. Therefore, little is still known concerning severity and change of craniofacial asymmetry with aging. The authors analyzed preoperative craniofacial asymmetry objectively and confirmed relationship between craniofacial asymmetry and aging in CMT patients who got surgical release.
The authors retrospectively measured preoperative craniofacial asymmetry using cranial vault asymmetry index (CVAI) and inter-commissural angle (ICA) and reviewed preoperative rotational and flexional deficit of neck movement for 123 CMT patients who underwent complete tight fibrous band release and resection at the Center for Torticollis, Ajou Medical Center from February 2007 to February 2011. The relationship between CVAI, ICA, rotational deficit, and flexional deficit, and age at operation were analyzed. Mean values of CVAI, ICA, rotational deficit, and flexional deficit were compared between the age groups, after grouping the patients by age (Age Group 1, surgically treated before the age of 1 year; Age Group 2, from 1 to 3 years; Age Group 3, from 3 to5 years; Age Group 4, from 5 to 10 years; and Age Group 5, after 10 years).
Mean age at operation was 82.5 months (range, 5-498 months). Seventy-one percent (n=87) of patients had a significant cranial asymmetry and eighty-seven percent (n=107) of patients had a significant facial asymmetry. In correlation analysis, ICA increased proportionally to age (Pearson correlation coefficient r=0.334, p=0.000), especially patients under 3 years old (r=0.42, p =0.001). CVAI was unrelated to age, rotational deficit, and flexional deficit. Rotational deficit decreased proportionally to age (r=-0.229, p=0.032). In ANOVA test, ICA and rotational deficit between the age groups were statistically significantly different (p<0.05)
In congenital muscular torticollis, facial asymmetry is progressive if the contracted SCM muscle is not released although cranial asymmetry is already determined younger than 6 months old. Early operation should be considered to prevent progression of facial asymmetry in CMT patients if they need surgical release.
ABSTRAT i
TABLE OF CONTENTS iii
LIST OF FIGURES iv
LIST OF TABLES v
I. INTRODUCTION 1
II. MATERIALS AND METHODS 3
A. Method of Assessment 3
B. Assessment of Result 4
III. RESULTS 5
IV. DISCUSSION 12
V. CONCLUSION 16
REFERENCES 17
국문요약 20
Master
Advisors/Committee Members: 대학원 의학과, 201024241, 서, 승조.
Subjects/Keywords: Congenital muscular torticollis; Craniofacial asymmetry
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
서, . (2012). Is craniofacial asymmetry progressive in the untreated congenital muscular torticollis?. (Thesis). Ajou University. Retrieved from http://repository.ajou.ac.kr/handle/201003/7601 ; http://dcoll.ajou.ac.kr:9080/dcollection/jsp/common/DcLoOrgPer.jsp?sItemId=000000012967
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
서, 승조. “Is craniofacial asymmetry progressive in the untreated congenital muscular torticollis?.” 2012. Thesis, Ajou University. Accessed March 05, 2021.
http://repository.ajou.ac.kr/handle/201003/7601 ; http://dcoll.ajou.ac.kr:9080/dcollection/jsp/common/DcLoOrgPer.jsp?sItemId=000000012967.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
서, 승조. “Is craniofacial asymmetry progressive in the untreated congenital muscular torticollis?.” 2012. Web. 05 Mar 2021.
Vancouver:
서 . Is craniofacial asymmetry progressive in the untreated congenital muscular torticollis?. [Internet] [Thesis]. Ajou University; 2012. [cited 2021 Mar 05].
Available from: http://repository.ajou.ac.kr/handle/201003/7601 ; http://dcoll.ajou.ac.kr:9080/dcollection/jsp/common/DcLoOrgPer.jsp?sItemId=000000012967.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
서 . Is craniofacial asymmetry progressive in the untreated congenital muscular torticollis?. [Thesis]. Ajou University; 2012. Available from: http://repository.ajou.ac.kr/handle/201003/7601 ; http://dcoll.ajou.ac.kr:9080/dcollection/jsp/common/DcLoOrgPer.jsp?sItemId=000000012967
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Florida
5.
Bamaga, Ibraheem Khamis.
Craniofacial Deformity and Malocclusion in a Mouse Model of Neurofibromatosis Type I (NF1).
Degree: PhD, Medical Sciences - Molecular Cell Biology (IDP), 2017, University of Florida
URL: https://ufdc.ufl.edu/UFE0051022
Subjects/Keywords: craniofacial; neurofibromatosis
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
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APA (6th Edition):
Bamaga, I. K. (2017). Craniofacial Deformity and Malocclusion in a Mouse Model of Neurofibromatosis Type I (NF1). (Doctoral Dissertation). University of Florida. Retrieved from https://ufdc.ufl.edu/UFE0051022
Chicago Manual of Style (16th Edition):
Bamaga, Ibraheem Khamis. “Craniofacial Deformity and Malocclusion in a Mouse Model of Neurofibromatosis Type I (NF1).” 2017. Doctoral Dissertation, University of Florida. Accessed March 05, 2021.
https://ufdc.ufl.edu/UFE0051022.
MLA Handbook (7th Edition):
Bamaga, Ibraheem Khamis. “Craniofacial Deformity and Malocclusion in a Mouse Model of Neurofibromatosis Type I (NF1).” 2017. Web. 05 Mar 2021.
Vancouver:
Bamaga IK. Craniofacial Deformity and Malocclusion in a Mouse Model of Neurofibromatosis Type I (NF1). [Internet] [Doctoral dissertation]. University of Florida; 2017. [cited 2021 Mar 05].
Available from: https://ufdc.ufl.edu/UFE0051022.
Council of Science Editors:
Bamaga IK. Craniofacial Deformity and Malocclusion in a Mouse Model of Neurofibromatosis Type I (NF1). [Doctoral Dissertation]. University of Florida; 2017. Available from: https://ufdc.ufl.edu/UFE0051022

University of Toronto
6.
Maloul, Asmaa.
Biomechanical Characterization of Complex Thin Bone structures in The Human Craniofacial Skeleton.
Degree: 2012, University of Toronto
URL: http://hdl.handle.net/1807/32760
► In spite of burgeoning of new technologies in the field of maxillofacial surgery, such as novel methods for osteosynthesis, bone substitution and bone regeneration, the…
(more)
▼ In spite of burgeoning of new technologies in the field of maxillofacial surgery, such as novel methods for osteosynthesis, bone substitution and bone regeneration, the reconstruction of the craniofacial skeleton (CFS) remains a challenge. Complications and failure in existing technologies and treatments for the CFS may be attributed in part to an incomplete understanding of the biomechanical environment in which these technologies are expected to perform. Characterizing the morphology and biomechanical behaviour of this complex and unique structure is important to understanding its global response to mechanical demands. This thesis aims to characterize the biomechanical behaviour of thin bone regions and sutures in the CFS. We investigated the impact of image degradation in CT scans on the ability to develop accurate specimen-specific FE models. Image degradation resulted in large increases in cortical thickness and decreases in scan intensity, which corresponded to significant changes in maximum principal strains in the FE models. A new semi-automated connectivity technique was developed to quantify the degree of fusion in sutures and revealed varying degrees of connectivity and interdigitation depending on the suture location. Morphological features characterized using this technique were incorporated into idealized suture FE models and analysed under multiple loading directions. The idealized FE models revealed that the impact of the number of interdigitations on the strain energy absorption in the suture/bone complex is dependent on the loading direction (inversely related under pressure and directly related under perpendicular and pressure loading); similar behaviour was seen in a μCT based specimen-specific FE model. Three-point bending tests on bone samples containing sutures revealed a positive correlation between the number of interdigitations and bending strength. Finally, experimental testing of full cadaveric heads demonstrated inter-specimen consistency in strain magnitude and direction under muscle loading in spite of morphological differences. Overall, these findings provide new insight into the complex morphology of the CFS, limitations of current clinical imaging and the biomechanical behaviour of thin bone structures and their articulations. This work forms a solid foundation for future development of image analysis, modeling and experimental investigations focused on characterizing the global behaviour of the CFS.
PhD
Advisors/Committee Members: Cari, Whyne, Biomedical Engineering.
Subjects/Keywords: Craniofacial; Biomechanics; Sutures; CT; 0541
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Maloul, A. (2012). Biomechanical Characterization of Complex Thin Bone structures in The Human Craniofacial Skeleton. (Doctoral Dissertation). University of Toronto. Retrieved from http://hdl.handle.net/1807/32760
Chicago Manual of Style (16th Edition):
Maloul, Asmaa. “Biomechanical Characterization of Complex Thin Bone structures in The Human Craniofacial Skeleton.” 2012. Doctoral Dissertation, University of Toronto. Accessed March 05, 2021.
http://hdl.handle.net/1807/32760.
MLA Handbook (7th Edition):
Maloul, Asmaa. “Biomechanical Characterization of Complex Thin Bone structures in The Human Craniofacial Skeleton.” 2012. Web. 05 Mar 2021.
Vancouver:
Maloul A. Biomechanical Characterization of Complex Thin Bone structures in The Human Craniofacial Skeleton. [Internet] [Doctoral dissertation]. University of Toronto; 2012. [cited 2021 Mar 05].
Available from: http://hdl.handle.net/1807/32760.
Council of Science Editors:
Maloul A. Biomechanical Characterization of Complex Thin Bone structures in The Human Craniofacial Skeleton. [Doctoral Dissertation]. University of Toronto; 2012. Available from: http://hdl.handle.net/1807/32760
7.
MARCO ANTONIO LORENZETTI.
ANÁLISE CEFALOMÉTRICA COMPARATIVA ENTRE CRIANÇAS RESPIRADORAS BUCAIS E NASAIS.
Degree: 2007, Universidade Metodista de São Paulo
URL: http://ibict.metodista.br/tedeSimplificado/tde_busca/arquivo.php?codArquivo=640
► Existem muitas controvérsias sobre a real interferência da respiração no crescimento craniofacial. Este estudo avaliou a possível relação da influência do padrão respiratório com as…
(more)
▼ Existem muitas controvérsias sobre a real interferência da respiração no crescimento craniofacial. Este estudo avaliou a possível relação da influência do padrão respiratório com as variáveis cefalométricas: 1) variáveis esqueléticas sagitais: convexidade do ponto A, profundidade facial, profundidade da maxila e comprimento do corpo mandibular; 2) variáveis esqueléticas verticais: altura facial inferior, eixo facial, cone facial, plano palatal, plano mandibular, altura facial posterior e arco mandibular; 3) variáveis dentárias: protrusão do incisivo inferior e protrusão do incisivo superior. A amostra constituiu-se de 120 crianças do sexo masculino e do sexo feminino com más-oclusões dentárias de Classe I e II-1, respiradores bucais e nasais na fase da dentadura mista e permanente, com indicação para tratamento ortodôntico. Após as avaliações ortodôntica, otorrinolaringológica e fonoaudiológica a amostra foi dividida em 2 grupos: 60 crianças portadoras de más-oclusões Classe I e Classe II-1 respiradoras bucais e 60 crianças portadoras de más-oclusões Classe I e Classe II-1 respiradoras nasais, sendo cada grupo divididos em 3 subgrupos nas faixas etárias: 7 a 8 anos, 9 a 10 anos e 11 a 12 anos. Após a obtenção dos resultados e a interpretação da análise estatística, foi possível concluir que: 1) das relações entre os padrões respiratórios (bucal e nasal) e as variáveis esqueléticas sagitais: constatou-se que houve diferença estatisticamente significante, apresentando-se as variáveis cefalométricas: Convexidade pto. A: aumentada no grupo de respiração bucal, idade de 7 a 8 anos com má-oclusão Classe I. Profundidade facial : aumentada no grupo de respiração bucal, idade de 9 a 10 anos com má-oclusão Classe II-1. Profundidade maxila: aumentada no grupo de respiração bucal, idade de 9 a 10 anos com má-oclusão Classe II-1; 2) das relações entre os padrões respiratórios (bucal e nasal) e as variáveis esqueléticas verticais: constatou-se que houve diferença estatisticamente significante, apresentando-se as variáveis cefalométricas: Cone facial: diminuída no grupo de respiração bucal, idade 9 a 10 anos com má-oclusão Classe I. Arco mandibular : diminuída no grupo de respiração bucal, idade 7 a 8 anos com má-oclusão Classe II-1.; 3) das relações entre os padrões respiratórios (bucal e nasal) e as variáveis dentárias: constatou-se que não houve diferença estatisticamente significante para nenhuma das variáveis dentárias analisadas: protrusão do incisivo inferior e superior , não se relacionando com os padrões respiratórios (bucal e nasal).
There are several controversies on the real interference from breathing on craniofacial growth. This study evaluated the possible relationship of the influence of breathing pattern with cephalometric variables: 1) sagittal skeletal variables: convexity of point A, facial depth, maxillary depth and mandibular body length; 2) vertical skeletal variables: lower facial height, facial axis, facial cone, palatal plane, mandibular plane, posterior facial height and mandibular arch; 3) dental…
Advisors/Committee Members: Marco Antonio Scanavini, Eduardo Kazuo Sannomiya, Rodrigo Generoso Carlos.
Subjects/Keywords: Respiração bucal; Cefalometria; Crescimento craniofacial; ORTODONTIA; Mouth breathing; Cephalometrics; Craniofacial growth
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
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APA (6th Edition):
LORENZETTI, M. A. (2007). ANÁLISE CEFALOMÉTRICA COMPARATIVA ENTRE CRIANÇAS RESPIRADORAS BUCAIS E NASAIS. (Thesis). Universidade Metodista de São Paulo. Retrieved from http://ibict.metodista.br/tedeSimplificado/tde_busca/arquivo.php?codArquivo=640
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
LORENZETTI, MARCO ANTONIO. “ANÁLISE CEFALOMÉTRICA COMPARATIVA ENTRE CRIANÇAS RESPIRADORAS BUCAIS E NASAIS.” 2007. Thesis, Universidade Metodista de São Paulo. Accessed March 05, 2021.
http://ibict.metodista.br/tedeSimplificado/tde_busca/arquivo.php?codArquivo=640.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
LORENZETTI, MARCO ANTONIO. “ANÁLISE CEFALOMÉTRICA COMPARATIVA ENTRE CRIANÇAS RESPIRADORAS BUCAIS E NASAIS.” 2007. Web. 05 Mar 2021.
Vancouver:
LORENZETTI MA. ANÁLISE CEFALOMÉTRICA COMPARATIVA ENTRE CRIANÇAS RESPIRADORAS BUCAIS E NASAIS. [Internet] [Thesis]. Universidade Metodista de São Paulo; 2007. [cited 2021 Mar 05].
Available from: http://ibict.metodista.br/tedeSimplificado/tde_busca/arquivo.php?codArquivo=640.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
LORENZETTI MA. ANÁLISE CEFALOMÉTRICA COMPARATIVA ENTRE CRIANÇAS RESPIRADORAS BUCAIS E NASAIS. [Thesis]. Universidade Metodista de São Paulo; 2007. Available from: http://ibict.metodista.br/tedeSimplificado/tde_busca/arquivo.php?codArquivo=640
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Alberta
8.
Westover, Lindsey M.
Evaluation of the Interface Mechanical Properties of
Craniofacial Implants and Natural Teeth Through Development of the
Advanced System for Implant Stability Testing (ASIST).
Degree: PhD, Department of Mechanical Engineering, 2016, University of Alberta
URL: https://era.library.ualberta.ca/files/cx059c7542
► Clinical evaluation of the integrity of the bone-implant interface of percutaneous implants is important to prescribe loading, to identify the risk of failure, and to…
(more)
▼ Clinical evaluation of the integrity of the
bone-implant interface of percutaneous implants is important to
prescribe loading, to identify the risk of failure, and to monitor
the long-term health of the implant. The same concept of interface
integrity can be applied in dentistry where the interface is the
periodontal ligament (PDL) connecting the tooth root to the
surrounding alveolar bone. Similarly, ongoing clinical evaluation
of tooth stability (or mobility) has important applications in
dental trauma, orthodontics, and periodontology. This clinical need
has led to the development of several noninvasive methods for
stability measurement of both percutaneous implant systems as well
as natural teeth. Many of these currently available systems rely on
resonance frequency analysis (RFA) or similar analysis of the
fundamental frequency of vibration of the system. With these
measurement techniques, the details of the system are not taken
into account in the interpretation. As a result, there is no clear
understanding of how the output values relate to the actual
stiffness characteristics at the interface. To have a better
understanding of the physical properties at the interface, a
coupled experimental-analytical modeling approach has been proposed
for percutaneous implants. The approach uses an acceleration
measurement during an impact with the abutment and an analytical
model is included in the interpretation to isolate the properties
at the interface. This study builds upon previous approaches to
develop a measurement system for noninvasive evaluation of
interface stiffness that is applicable across a range of
applications including bone anchored hearing aid (BAHA) implants
and natural teeth. The system is termed the Advanced System for
Implant Stability Testing (ASIST) and the interface stability
measure is termed the ASIST Stability Coefficient (ASC). The ASIST
is developed through in vitro laboratory testing for two commercial
BAHA systems. A comparison is presented between the developed ASIST
and the commercially available OsstellTM ISQ system for BAHA
stability measurement. The ASIST is then used in vivo with a
longitudinal clinical evaluation for BAHA patients during the first
year following surgery. The ASIST technique is also developed for
natural teeth and evaluated with longitudinal clinical data during
orthodontic treatment. Through in vitro laboratory testing, the
ASIST measure was found to be essentially independent of attached
components for BAHA implants with variations due to abutment length
of approximately 2.9 ASC (less than 10% of the measure). The ASIST
was shown to be sensitive enough to detect changes in interface
properties between different implant installations. The ASIST
showed significant advantages over the commercially available
OsstellTM ISQ system for stability measurement of BAHA systems. The
OsstellTM ISQ appears to be more sensitive to geometric variations
such as abutment length than actual changes in interface
properties, while the ASIST was found to be more sensitive to
interface…
Subjects/Keywords: Implant stability; Craniofacial Implants; Tooth mobility
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Westover, L. M. (2016). Evaluation of the Interface Mechanical Properties of
Craniofacial Implants and Natural Teeth Through Development of the
Advanced System for Implant Stability Testing (ASIST). (Doctoral Dissertation). University of Alberta. Retrieved from https://era.library.ualberta.ca/files/cx059c7542
Chicago Manual of Style (16th Edition):
Westover, Lindsey M. “Evaluation of the Interface Mechanical Properties of
Craniofacial Implants and Natural Teeth Through Development of the
Advanced System for Implant Stability Testing (ASIST).” 2016. Doctoral Dissertation, University of Alberta. Accessed March 05, 2021.
https://era.library.ualberta.ca/files/cx059c7542.
MLA Handbook (7th Edition):
Westover, Lindsey M. “Evaluation of the Interface Mechanical Properties of
Craniofacial Implants and Natural Teeth Through Development of the
Advanced System for Implant Stability Testing (ASIST).” 2016. Web. 05 Mar 2021.
Vancouver:
Westover LM. Evaluation of the Interface Mechanical Properties of
Craniofacial Implants and Natural Teeth Through Development of the
Advanced System for Implant Stability Testing (ASIST). [Internet] [Doctoral dissertation]. University of Alberta; 2016. [cited 2021 Mar 05].
Available from: https://era.library.ualberta.ca/files/cx059c7542.
Council of Science Editors:
Westover LM. Evaluation of the Interface Mechanical Properties of
Craniofacial Implants and Natural Teeth Through Development of the
Advanced System for Implant Stability Testing (ASIST). [Doctoral Dissertation]. University of Alberta; 2016. Available from: https://era.library.ualberta.ca/files/cx059c7542

University of Toronto
9.
Yen, Dao-Pei Laurene.
Expression Analysis of CTHRC1 in the Murine Embryo during Mid-facial Development.
Degree: 2014, University of Toronto
URL: http://hdl.handle.net/1807/67908
► Collagen Triple Helix Repeat Containing 1 (CTHRC1) has been shown to regulate collagen expression, cell migration and interact with the Wnt/planar cell polarity pathway. Objective:…
(more)
▼ Collagen Triple Helix Repeat Containing 1 (CTHRC1) has been shown to regulate collagen expression, cell migration and interact with the Wnt/planar cell polarity pathway. Objective: Determine CTHRC1 expression in the midface of mouse embryos during craniofacial development. Methods: qPCR and immunohistochemistry were used to determine the expression of Cthrc1 at embryonic (E) days of development E8.5-E13.5. Results: CTHRC1 expression was in the notochord and neural tube at E8.5, mesenchyme of the midface at E9.5-E10.5 and areas of cartilage formation at E11.5-E13.5. Conclusions: The expression of CTHRC1 in the developing craniofacial region suggests a role of CTHRC1 in migration of cranial neural crest cells and in chondrocyte proliferation and differentiation. We speculate the functions of CTHRC1 during craniofacial development are via its interactions with the Wnt/PCP pathway, shown previously to play a significant role during craniofacial development. Support: Donald G. Woodside Fund and NSERC.
M.Sc.
Advisors/Committee Members: Gong, Siew-Ging, Dentistry.
Subjects/Keywords: craniofacial development; Cthrc1; Midface; Murine embryo; 0758
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Yen, D. L. (2014). Expression Analysis of CTHRC1 in the Murine Embryo during Mid-facial Development. (Masters Thesis). University of Toronto. Retrieved from http://hdl.handle.net/1807/67908
Chicago Manual of Style (16th Edition):
Yen, Dao-Pei Laurene. “Expression Analysis of CTHRC1 in the Murine Embryo during Mid-facial Development.” 2014. Masters Thesis, University of Toronto. Accessed March 05, 2021.
http://hdl.handle.net/1807/67908.
MLA Handbook (7th Edition):
Yen, Dao-Pei Laurene. “Expression Analysis of CTHRC1 in the Murine Embryo during Mid-facial Development.” 2014. Web. 05 Mar 2021.
Vancouver:
Yen DL. Expression Analysis of CTHRC1 in the Murine Embryo during Mid-facial Development. [Internet] [Masters thesis]. University of Toronto; 2014. [cited 2021 Mar 05].
Available from: http://hdl.handle.net/1807/67908.
Council of Science Editors:
Yen DL. Expression Analysis of CTHRC1 in the Murine Embryo during Mid-facial Development. [Masters Thesis]. University of Toronto; 2014. Available from: http://hdl.handle.net/1807/67908

Univerzitet u Beogradu
10.
Ivanjac, Filip, 1983-.
Merenje stabilnosti kraniofacijalnih implantata analizom
rezonantne frekvencije.
Degree: Stomatološki fakultet, 2016, Univerzitet u Beogradu
URL: https://fedorabg.bg.ac.rs/fedora/get/o:13327/bdef:Content/get
► Stomatologija - Maksilofacijalna hirurgija / Denistry - Maxillofacial surgery
Klinički je dokazano da stabilnost implantata igra značajnu ulogu u narednim terapijskim fazama i omogućava da…
(more)
▼ Stomatologija - Maksilofacijalna hirurgija /
Denistry - Maxillofacial surgery
Klinički je dokazano da stabilnost implantata igra
značajnu ulogu u narednim terapijskim fazama i omogućava da
predvidimo krajnji ishod rehabilitacije. Kako uspeh
implantatno-protetičkog zbrinjavanja često zavisi od biomehaničkih
faktora, podatak o stabilnosti implantata smanjuje rizik od
neuspeha. Istraţivanja stabilnosti implantata uglavnom se odnose na
oralne implantate. U maksilofacijalnoj hirurgiji za fiksiranje
kraniofacijalnih epiteza koriste se ekstraoralni implantati. Stoga
se ukazala potreba da se sprovede pilot studija u okviru koje bi se
izmerila stabilnost kraniofacijalnih implantata analizom rezonantne
frekvencije. Cilj ovog istraţivanja bila je procena stabilnosti
kraniofacijalnih implantata analizom rezonantne frekvencije u
korelaciji sa oseointegracijom u funkciji vremena, oblikom
implantata i njihovom lokalizacijom. Metodologija: Na osnovu mikro
CT metode odreĎena je gustina kosti na kadaveričnom modelu lobanje
radi utvrĎivanja optimalne lokalizacije mesta za ugradnju
kraniofacijalnih implantata. Istraţivanjem je obuhvaćeno 20
pacijenata od toga 11 sa orbitalnim, 5 sa nazalnim i 4 sa
aurikularnim (kontrolna grupa) defektima. Ukupno 50 EO implantata
je ugraĎeno. Korišćeni su implantati oblika diska - 38 (jednostruki
8, dvostruki 19 i trostruki disk 11). U kontrolnoj grupi bilo je
ugraĎenih 12 zavrtanj implantata prečnika 4.1 mm; 3.5 mm duţine.
Stabilnost je merena Ostell mentor® aparatom. Merenja su vršena tri
puta, neposredno po ugradnji implantata, nakon 3 meseca, kao i
nakon najmanje 6 meseci. Rezultati: Na osnovu analize rezonantne
frekvencije (RFA) značajno povećanje vrednosti implantatne
stabilnosti zabeleţeno je izmeĎu sva tri vremena merenja, kod svih
tipova implantata, osim kod trostrukih disk implantata izmeĎu 3. i
6. meseca, kao i kod zavrtanj implantata izmeĎu 0. i 3. meseca.
PoreĎenjem izmeĎu grupa implantati oblika zavrtnja pokazali su
statistički značajno više vrednosti stabilnosti u odnosu na disk
implantate. MeĎusobnim poreĎenjem disk implantata nije pronaĎena
statistički značajna razlika u stabilnosti izmeĎu jednostrukih,
dvostrukih i trostrukih disk implantata tokom vremena, osim u
trećem mesecu gde su trostruki disk implantati pokazali statistički
značajno više vrednosti u odnosu na jednostruke disk implantate.
Zaključak: Kod svih pacijenata implantatna stabilnost povećavala se
tokom vremena što potvrĎuje dobru oseointegraciju. Nakon 3 meseca 6
implantati su bili dovoljno stabilni za retenciju
epiteza...
Advisors/Committee Members: Konstantinović, Vitomir, 1961-.
Subjects/Keywords: craniofacial implants; implant stability; resonant
frequency analysis
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Ivanjac, Filip, 1. (2016). Merenje stabilnosti kraniofacijalnih implantata analizom
rezonantne frekvencije. (Thesis). Univerzitet u Beogradu. Retrieved from https://fedorabg.bg.ac.rs/fedora/get/o:13327/bdef:Content/get
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Ivanjac, Filip, 1983-. “Merenje stabilnosti kraniofacijalnih implantata analizom
rezonantne frekvencije.” 2016. Thesis, Univerzitet u Beogradu. Accessed March 05, 2021.
https://fedorabg.bg.ac.rs/fedora/get/o:13327/bdef:Content/get.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Ivanjac, Filip, 1983-. “Merenje stabilnosti kraniofacijalnih implantata analizom
rezonantne frekvencije.” 2016. Web. 05 Mar 2021.
Vancouver:
Ivanjac, Filip 1. Merenje stabilnosti kraniofacijalnih implantata analizom
rezonantne frekvencije. [Internet] [Thesis]. Univerzitet u Beogradu; 2016. [cited 2021 Mar 05].
Available from: https://fedorabg.bg.ac.rs/fedora/get/o:13327/bdef:Content/get.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Ivanjac, Filip 1. Merenje stabilnosti kraniofacijalnih implantata analizom
rezonantne frekvencije. [Thesis]. Univerzitet u Beogradu; 2016. Available from: https://fedorabg.bg.ac.rs/fedora/get/o:13327/bdef:Content/get
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Illinois – Urbana-Champaign
11.
Weisgerber, Daniel W.
Design, characterization, and reinforcement of mineralized collagen-glycosaminoglycan scaffolds for orthopedic wound repair.
Degree: PhD, Materials Science & Engr, 2015, University of Illinois – Urbana-Champaign
URL: http://hdl.handle.net/2142/89143
► The treatment of craniofacial orthopedic defects remains a challenge due to the large size, complex geometry, and load bearing aspects that often accompany such defects.…
(more)
▼ The treatment of
craniofacial orthopedic defects remains a challenge due to the large size, complex geometry, and load bearing aspects that often accompany such defects. The typical treatment or correction of
craniofacial defects employed during surgical intervention of such injuries often necessitates the use of either autologous or allogenic bone grafts for orthopedic implants as the gold standard. However, this standard of treatment has been plagued with concerns over the size, geometry, donor site morbidity, disease transmission, and availability. To address these concerns, the development of an alternative orthopedic implant biomaterial capable of: (1) flexible design for meeting bone, defect, and patient specific treatment criteria; (2) guiding and supporting cellular specific repair specific to orthopedic defects; (3) demonstrate mechanical competence for surgical implantation and subsequent loading during function. This work outlines the development of a collagen-glycosaminoglycan platform that satisfies these requirements for the treatment of
craniofacial defects. Chapter 2 details the fabrication and characterization of the collagen-glycosaminoglycan scaffold biochemical and biophysical properties important for the bioactivity and interaction with target cellular populations. The chapter 3 evaluates the in vitro cellular response and subsequent remodeling of a relevant cell population, mesenchymal stem cells, within the collagen-glycosaminoglycan scaffold. Chapter 4 addresses the necessary mechanical reinforcement and subsequent characterization of a multi-scale polycaprolactone-collagen-glycosaminoglycan composite biomaterial for in vivo implantation and culture. In chapter 5 the polycaprolactone-collagen-glycosaminoglycan composite was then implanted in a subcritical mandibular ramus defect to affirm the composites in vivo efficacy. Finally, chapter 6 evaluated possible alterations in the collagen-glycosaminoglycan scaffold design for enhancing cellular behavior, while chapter 7 expanded upon the multi-compartment collagen-glycosaminoglycan scaffold design for the treatment of
craniofacial defects and associated entheses.
Advisors/Committee Members: Harley, Brendan (advisor), Harley, Brendan (Committee Chair), Braun, Paul (committee member), Cheng, Jianjun (committee member), Leal, Cecilia (committee member).
Subjects/Keywords: collagen scaffold; biomaterial; craniofacial repair; bone
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Weisgerber, D. W. (2015). Design, characterization, and reinforcement of mineralized collagen-glycosaminoglycan scaffolds for orthopedic wound repair. (Doctoral Dissertation). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/89143
Chicago Manual of Style (16th Edition):
Weisgerber, Daniel W. “Design, characterization, and reinforcement of mineralized collagen-glycosaminoglycan scaffolds for orthopedic wound repair.” 2015. Doctoral Dissertation, University of Illinois – Urbana-Champaign. Accessed March 05, 2021.
http://hdl.handle.net/2142/89143.
MLA Handbook (7th Edition):
Weisgerber, Daniel W. “Design, characterization, and reinforcement of mineralized collagen-glycosaminoglycan scaffolds for orthopedic wound repair.” 2015. Web. 05 Mar 2021.
Vancouver:
Weisgerber DW. Design, characterization, and reinforcement of mineralized collagen-glycosaminoglycan scaffolds for orthopedic wound repair. [Internet] [Doctoral dissertation]. University of Illinois – Urbana-Champaign; 2015. [cited 2021 Mar 05].
Available from: http://hdl.handle.net/2142/89143.
Council of Science Editors:
Weisgerber DW. Design, characterization, and reinforcement of mineralized collagen-glycosaminoglycan scaffolds for orthopedic wound repair. [Doctoral Dissertation]. University of Illinois – Urbana-Champaign; 2015. Available from: http://hdl.handle.net/2142/89143

University of Southern California
12.
Zuniga, Elizabeth.
Jagged-notch signaling: patterning the vertebrate
face.
Degree: PhD, Neuroscience, 2012, University of Southern California
URL: http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll3/id/102586/rec/3683
► Craniofacial abnormalities are the most common birth defects, and yet little is known about the developmental etiology that leads to mispatterning of the face. Several…
(more)
▼ Craniofacial abnormalities are the most common birth
defects, and yet little is known about the developmental etiology
that leads to mispatterning of the face. Several studies have shown
that the development of the face depends on the regionalization of
neural crest precursors into distinct domains along the
dorsoventral (DV) axis. Previous research has shown Endothelin 1
(Edn1) is required for patterning the ventral (lower) face, in part
by regulating the expression of ventral genes such as those of the
Dlx family. However, little is known about the factors required for
development of the dorsal (upper) face. By analyzing a newly
identified zebrafish jag1b mutant and transgenic overexpressing
JAGGED1, we find that Jagged-Notch signaling promotes dorsal
identity by repressing ventral gene expression. Jagged ligands are
thought to act primarily as ligands for Notch receptors, with
cleavage and nuclear translocation of a Notch intracellular domain
(NICD) affecting gene transcription. Surprisingly, we find that
transgenic misexpression of JAGGED1 intracellular domain (JICD),
which lacks the extracellular domain required for Notch binding,
produces facial skeletal and DV gene expression defects similar to
those seen upon misexpression of full-length JAGGED1. These
findings lead us to propose a novel cell-autonomous role for Jagged
in transcriptional regulation responsible for patterning the dorsal
face. Next, we identified the Bmp antagonist Gremlin2 as a target
of both Jagged-Notch and Edn1 signaling with Grem2 being required
to restrict Bmp activity to the ventral-most domain of the arches.
Using gain- and loss-of-function studies, we revealed a complex
genetic interaction among Jagged, Edn1, and Bmp signaling in
specifying distinct skeletal fates along the DV facial axis. Taken
all together, our findings are the first to show how Jagged is
involved in regional patterning of the face. Mutations in Jagged
are found in patients with Alagille syndrome who often have a
characteristic facial dysmorphology. Thus determining how Jagged
patterns the face will lead us closer in understanding how a
disruption in this pathway results in facial anomalies in
humans.
Advisors/Committee Members: Crump, Gage D. (Committee Chair), Maxson, Robert E., Jr. (Committee Member), Segil, Neil (Committee Member), Butler, Samantha (Committee Member), Ma, Le (Committee Member).
Subjects/Keywords: craniofacial; Jagged1; Notch2; zebrafish; Edn1; Bmp
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Zuniga, E. (2012). Jagged-notch signaling: patterning the vertebrate
face. (Doctoral Dissertation). University of Southern California. Retrieved from http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll3/id/102586/rec/3683
Chicago Manual of Style (16th Edition):
Zuniga, Elizabeth. “Jagged-notch signaling: patterning the vertebrate
face.” 2012. Doctoral Dissertation, University of Southern California. Accessed March 05, 2021.
http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll3/id/102586/rec/3683.
MLA Handbook (7th Edition):
Zuniga, Elizabeth. “Jagged-notch signaling: patterning the vertebrate
face.” 2012. Web. 05 Mar 2021.
Vancouver:
Zuniga E. Jagged-notch signaling: patterning the vertebrate
face. [Internet] [Doctoral dissertation]. University of Southern California; 2012. [cited 2021 Mar 05].
Available from: http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll3/id/102586/rec/3683.
Council of Science Editors:
Zuniga E. Jagged-notch signaling: patterning the vertebrate
face. [Doctoral Dissertation]. University of Southern California; 2012. Available from: http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll3/id/102586/rec/3683

University of Southern California
13.
Bhatt, Archana.
Mesenchymal stem cells from human gingiva ameliorate murine
alimentary mucositis.
Degree: MS, Cranio-Facial Biology, 2011, University of Southern California
URL: http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll127/id/478625/rec/4050
► Mucositis of the alimentary tract (AT) or alimentary mucositis is a debilitating adverse effect of cancer therapies in a high percentage of patients receiving chemotherapy,…
(more)
▼ Mucositis of the alimentary tract (AT) or alimentary
mucositis is a debilitating adverse effect of cancer therapies in a
high percentage of patients receiving chemotherapy, bone marrow
transplantation, and high-dose radiation to the head and neck. This
common oral complication bears a high impact on health, quality of
life, a patient’s ability to adhere with the prescribed therapies,
as well as the overall economic outcome. Relatively little is known
of the pathophysiology of mucositis and current therapeutic
interventions are ineffective. Recently a new population of
mesenchymal stem cells from human gingiva (hGMSC) have been
discovered (Zhang et al., 2009), which exhibit not only multipotent
differentiation and self-renewal capacities, but also possess
distinct immunomodulatory functions.; We hypothesized that
treatment with hGMSC reduces epithelial injuries and ameliorates
mucositis of the alimentary tract (AT) associated with cancer
therapies. We explored the feasibility of using hGMSC to reduce the
incidence and severity of mucositis induced by cancer therapies. We
observed a significant reduction of AT mucositis and recovery of
body weight in nearly 100% of mice undergoing one-dose treatment
with hGMSC. Treatment with hGMSC was capable of reducing the
incidence and severity of mucosal ulceration, promoting
proliferation of mucosal epithelial cells and the regeneration of
damaged crypts at the histological level. Our findings suggest that
hGMSCs can ameliorate mucositis by promoting the regeneration of
chemotherapy and/or radiotherapy induced mucosal damage. Thus,
hGMSC cell therapy may be a potential agent in the prevention and
treatment of AT mucositis.
Advisors/Committee Members: Le, Anh (Committee Chair), Hill, Colin (Committee Member), Paine, Michael (Committee Member).
Subjects/Keywords: stem cells; craniofacial biology; oral mucositis
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Bhatt, A. (2011). Mesenchymal stem cells from human gingiva ameliorate murine
alimentary mucositis. (Masters Thesis). University of Southern California. Retrieved from http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll127/id/478625/rec/4050
Chicago Manual of Style (16th Edition):
Bhatt, Archana. “Mesenchymal stem cells from human gingiva ameliorate murine
alimentary mucositis.” 2011. Masters Thesis, University of Southern California. Accessed March 05, 2021.
http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll127/id/478625/rec/4050.
MLA Handbook (7th Edition):
Bhatt, Archana. “Mesenchymal stem cells from human gingiva ameliorate murine
alimentary mucositis.” 2011. Web. 05 Mar 2021.
Vancouver:
Bhatt A. Mesenchymal stem cells from human gingiva ameliorate murine
alimentary mucositis. [Internet] [Masters thesis]. University of Southern California; 2011. [cited 2021 Mar 05].
Available from: http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll127/id/478625/rec/4050.
Council of Science Editors:
Bhatt A. Mesenchymal stem cells from human gingiva ameliorate murine
alimentary mucositis. [Masters Thesis]. University of Southern California; 2011. Available from: http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll127/id/478625/rec/4050

University of Southern California
14.
Mahabady, Susan.
Local and systemic responses to craniofacial osteolytic
defects in an animal model.
Degree: MS, Cranio-Facial Biology, 2013, University of Southern California
URL: http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll3/id/292774/rec/3850
► Aggregatibacter actinomycetemcomitans (Aa) is a well-known disease pathogen associated with oral infections. Although Aa readily forms biofilms in vitro and in vivo, little is known…
(more)
▼ Aggregatibacter actinomycetemcomitans (Aa) is a
well-known disease pathogen associated with oral infections.
Although Aa readily forms biofilms in vitro and in vivo, little is
known about its pathogenesis or the role of host immune responses.
In this study, we used an Aa biofilm-inoculated titanium implant
animal model and a calvarial lesion animal model to study local and
systemic responses to
craniofacial osteolytic defects. Analysis
included evaluation of clinical inflammation, micro-computed
tomography of bone volume, polymerase chain reaction of Aa
persistence, and Western blot analysis of antibody production.
Necropsies were performed for all study animals. Five out of 15
rats treated with Aa biofilm-inoculated implants died during
treatment. Following necropsy of this subset of animals, cause of
death was likely Aa sepsis leading to multi-system organ
dysfunction. These results may be important for future
investigations in understanding pathogenic mechanisms of local and
systemic host-pathogen responses as they relate to oral
biofilms.
Advisors/Committee Members: Sedghizadeh, P. Parish (Committee Chair), Paine, Michael L. (Committee Member), Zadeh, Homayoun H. (Committee Member).
Subjects/Keywords: Aggregatibacter actinomycetemcomitans; biofilm; craniofacial; osteolytic; peri-implantitis
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Mahabady, S. (2013). Local and systemic responses to craniofacial osteolytic
defects in an animal model. (Masters Thesis). University of Southern California. Retrieved from http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll3/id/292774/rec/3850
Chicago Manual of Style (16th Edition):
Mahabady, Susan. “Local and systemic responses to craniofacial osteolytic
defects in an animal model.” 2013. Masters Thesis, University of Southern California. Accessed March 05, 2021.
http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll3/id/292774/rec/3850.
MLA Handbook (7th Edition):
Mahabady, Susan. “Local and systemic responses to craniofacial osteolytic
defects in an animal model.” 2013. Web. 05 Mar 2021.
Vancouver:
Mahabady S. Local and systemic responses to craniofacial osteolytic
defects in an animal model. [Internet] [Masters thesis]. University of Southern California; 2013. [cited 2021 Mar 05].
Available from: http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll3/id/292774/rec/3850.
Council of Science Editors:
Mahabady S. Local and systemic responses to craniofacial osteolytic
defects in an animal model. [Masters Thesis]. University of Southern California; 2013. Available from: http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll3/id/292774/rec/3850

California State University – Chico
15.
Chelotti, Kristin L.
Temporal analysis of craniofacial trauma in prehistoric California's Central Valley
.
Degree: 2013, California State University – Chico
URL: http://hdl.handle.net/10211.4/579
► Anthropological analyses of skeletal remains from prehistoric and historic populations have aided in the reconstruction of human behavioral patterns with reference to topics such as…
(more)
▼ Anthropological analyses of skeletal remains from prehistoric and historic
populations have aided in the reconstruction of human behavioral patterns with reference
to topics such as diet, activity patterns, and violence. Observation of skeletal
trauma can be suggestive of interpersonal violence, particularly when consideration is
given to the type, location, concentration, and patterning of injuries. Specifically,
trauma to
craniofacial elements is more commonly associated with intentional acts
rather than accidental injury.
Prehistoric violence in California???s Central Valley has been attributed to increased
human populations during the late Holocene, which, coupled with climatic instability,
strained the availability of resources in the region. Such pressures are argued
to have resulted in greater levels of violence due to the struggle over declining resources, which may be evident through the prevalence of
craniofacial trauma through time. To
test this, the present study includes the analysis of
craniofacial trauma using skeletal
remains from prehistoric archaeological sites dated between the Early and Late Periods
and situated in the Central Valley of California.
From a sample of 212 individuals, 44 traumatic injuries, primarily in the
form of antemortem cranial vault depressions and nasal fractures, were noted in 29
males and females. Comparisons by time period and anatomical location of injuries revealed
no significant difference in the prevalence of trauma. The highest levels of traumatic
injury were noted during the Middle Period followed by a considerable decline in
the Late Period, which does not support the expectation that behavioral patterns associated
with rapid population expansion and competition over resources resulted in an increase
in interpersonal violence during the late Holocene.
The positive relationship between trauma prevalence and sex indicated
males were more frequently affected. The uneven distribution of trauma within both
sexes suggested injuries were intentional and the distinct patterning of cranial vault
trauma observed between males and females implied differential exposure to violence.
Based on these patterns, males were more likely involved in face-to-face violent encounters
while female involvement is open to wider interpretation.
Though this study did not affirm each research expectation, the association
between population expansion, resource competition, and violence is supported by the
craniofacial trauma prevalence of 13.7 percent within the total sample, a level that canxi
not be underemphasized as it exceeds the majority of those reported in similar studies
within central California.
Advisors/Committee Members: Bartelink, Eric (advisor).
Subjects/Keywords: craniofacial trauma prehistoric Central Valley California
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Chelotti, K. L. (2013). Temporal analysis of craniofacial trauma in prehistoric California's Central Valley
. (Thesis). California State University – Chico. Retrieved from http://hdl.handle.net/10211.4/579
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Chelotti, Kristin L. “Temporal analysis of craniofacial trauma in prehistoric California's Central Valley
.” 2013. Thesis, California State University – Chico. Accessed March 05, 2021.
http://hdl.handle.net/10211.4/579.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Chelotti, Kristin L. “Temporal analysis of craniofacial trauma in prehistoric California's Central Valley
.” 2013. Web. 05 Mar 2021.
Vancouver:
Chelotti KL. Temporal analysis of craniofacial trauma in prehistoric California's Central Valley
. [Internet] [Thesis]. California State University – Chico; 2013. [cited 2021 Mar 05].
Available from: http://hdl.handle.net/10211.4/579.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Chelotti KL. Temporal analysis of craniofacial trauma in prehistoric California's Central Valley
. [Thesis]. California State University – Chico; 2013. Available from: http://hdl.handle.net/10211.4/579
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Duke University
16.
Rodriguez, Erica Janet.
Uncovering a Monosynaptic Trigemino-parabrachial Circuit Facilitating Heightened Craniofacial Pain Perception
.
Degree: 2018, Duke University
URL: http://hdl.handle.net/10161/16790
► Humans often rank craniofacial pain as more severe than body pain. Evidence suggests that a stimulus of the same intensity induces stronger pain in…
(more)
▼ Humans often rank
craniofacial pain as more severe than body pain. Evidence suggests that a stimulus of the same intensity induces stronger pain in the face than in the body. However, the underlying neural circuitry for the differential processing of facial versus bodily pain remains unknown. Interestingly, the lateral parabrachial nucleus (PBL), a critical node in the affective pain circuit, is activated more strongly by noxious stimulation of the face than of the hindpaw. Using a novel activity-dependent technology called CANE developed in our laboratory, we identified and selectively labeled noxious-stimulus-activated PBL neurons and performed comprehensive anatomical input–output mapping. Surprisingly, we uncovered a hitherto uncharacterized monosynaptic connection between cranial sensory neurons and the PBL-nociceptive neurons. Optogenetic activation of this monosynaptic
craniofacial-to-PBL projection induced robust escape and avoidance behaviors and stress calls, whereas optogenetic silencing specifically reduced facial nociception. The monosynaptic circuit revealed here provides a neural substrate for heightened
craniofacial affective pain.
Advisors/Committee Members: Wang, Fan (advisor).
Subjects/Keywords: Neurosciences;
Affective;
Circuits;
Craniofacial;
Pain;
Trigeminal
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Rodriguez, E. J. (2018). Uncovering a Monosynaptic Trigemino-parabrachial Circuit Facilitating Heightened Craniofacial Pain Perception
. (Thesis). Duke University. Retrieved from http://hdl.handle.net/10161/16790
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Rodriguez, Erica Janet. “Uncovering a Monosynaptic Trigemino-parabrachial Circuit Facilitating Heightened Craniofacial Pain Perception
.” 2018. Thesis, Duke University. Accessed March 05, 2021.
http://hdl.handle.net/10161/16790.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Rodriguez, Erica Janet. “Uncovering a Monosynaptic Trigemino-parabrachial Circuit Facilitating Heightened Craniofacial Pain Perception
.” 2018. Web. 05 Mar 2021.
Vancouver:
Rodriguez EJ. Uncovering a Monosynaptic Trigemino-parabrachial Circuit Facilitating Heightened Craniofacial Pain Perception
. [Internet] [Thesis]. Duke University; 2018. [cited 2021 Mar 05].
Available from: http://hdl.handle.net/10161/16790.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Rodriguez EJ. Uncovering a Monosynaptic Trigemino-parabrachial Circuit Facilitating Heightened Craniofacial Pain Perception
. [Thesis]. Duke University; 2018. Available from: http://hdl.handle.net/10161/16790
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Montana Tech
17.
Foltz, Lauren Elizabeth.
CELL SIGNALING PATHWAYS IN CONTROL OF NEUROBLASTOMA AND HUMAN NEURAL CREST DEVELOPMENT.
Degree: PhD, 2019, Montana Tech
URL: https://scholarworks.umt.edu/etd/11443
► Receptor Tyrosine Kinases (RTKs) are a family of cell surface receptors that bind extracellular ligands and initiate cellular signaling pathways. These pathways ultimately influence…
(more)
▼ Receptor Tyrosine Kinases (RTKs) are a family of cell surface receptors that bind extracellular ligands and initiate cellular signaling pathways. These pathways ultimately influence cellular behaviors such as cell proliferation, migration, and differentiation. Consequently, mutations and amplifications of RTK genes contribute to the development of several cancers, including neuroblastoma. Neuroblastoma originates from neural crest cells, which are formed as the neural tube closes during vertebrate development. The neural crest differentiates and migrates to form cells of several lineages including the peripheral nervous system, melanocytes, and craniofacial cartilage. These processes are tightly controlled by RTK signaling, and failures in differentiation may lead to uncontrolled cell growth and tumor formation. While extensive research has characterized individual RTK signaling pathways in control of neural crest differentiation, it is unknown how signals from several different receptors are integrated to produce a cellular response. In Chapter 2, we investigate the regulation of RTK activity through endocytosis, which controls RTK degradation and receptor recycling to the plasma membrane. Here we show that the SRC family kinases (SFKs) are located in endosomes of neuroblastoma cells, and are activated by RTKs. Furthermore, SFK localization within different endosome populations changed in response to signaling by ALK and KIT. The scaffold protein, PAG1, forms signaling complexes containing SFKs as well as members of other pathways downstream of RTKs. To understand how PAG1 directs pSFK endocytosis and sequestration, we generated a PAG1 protein lacking the transmembrane domain. We define a model where PAG1 directs pSFK localization in responses tailored to different receptors and overall signaling. PAG1 mutation increased SFK activity in cells, but decreased SFK activity in endosomes and reduced cell differentiation. In Chapter 3, to better understand differences in signaling between human neural crest and neuroblastoma, we generated neural crest stem cells from human embryonic stem cells. During differentiation, neural crest cells unexpectedly formed cartilage, a cell lineage derived from neural crest. We investigated the differentiation of craniofacial cartilage and developed a protocol for production of cartilage organoids. Organoids are a promising model for neural crest development as well as a potential source of cartilage for facial reconstructions.
Subjects/Keywords: cell signaling; craniofacial cartilage; neural crest; neuroblastoma
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Foltz, L. E. (2019). CELL SIGNALING PATHWAYS IN CONTROL OF NEUROBLASTOMA AND HUMAN NEURAL CREST DEVELOPMENT. (Doctoral Dissertation). Montana Tech. Retrieved from https://scholarworks.umt.edu/etd/11443
Chicago Manual of Style (16th Edition):
Foltz, Lauren Elizabeth. “CELL SIGNALING PATHWAYS IN CONTROL OF NEUROBLASTOMA AND HUMAN NEURAL CREST DEVELOPMENT.” 2019. Doctoral Dissertation, Montana Tech. Accessed March 05, 2021.
https://scholarworks.umt.edu/etd/11443.
MLA Handbook (7th Edition):
Foltz, Lauren Elizabeth. “CELL SIGNALING PATHWAYS IN CONTROL OF NEUROBLASTOMA AND HUMAN NEURAL CREST DEVELOPMENT.” 2019. Web. 05 Mar 2021.
Vancouver:
Foltz LE. CELL SIGNALING PATHWAYS IN CONTROL OF NEUROBLASTOMA AND HUMAN NEURAL CREST DEVELOPMENT. [Internet] [Doctoral dissertation]. Montana Tech; 2019. [cited 2021 Mar 05].
Available from: https://scholarworks.umt.edu/etd/11443.
Council of Science Editors:
Foltz LE. CELL SIGNALING PATHWAYS IN CONTROL OF NEUROBLASTOMA AND HUMAN NEURAL CREST DEVELOPMENT. [Doctoral Dissertation]. Montana Tech; 2019. Available from: https://scholarworks.umt.edu/etd/11443
18.
Moura, Priscila Padilha.
Refinamento fenotípico da disostose mandibulofacial tipo Bauru.
Degree: Mestrado, Fissuras Orofaciais, 2013, University of São Paulo
URL: http://www.teses.usp.br/teses/disponiveis/61/61132/tde-12112013-145300/
;
► Introdução: A DMF tipo Bauru (OMIM 604830 é uma condição genética caracterizada por hipoplasia malar, fissura orofacial, micrognatia, fendas palpebrais inclinadas para baixo e anomalia…
(more)
▼ Introdução: A DMF tipo Bauru (OMIM 604830 é uma condição genética caracterizada por hipoplasia malar, fissura orofacial, micrognatia, fendas palpebrais inclinadas para baixo e anomalia auricular. Herança autossômica dominante tem sido sugerida. Até o momento, seis casos com DMF tipo Bauru tem sido relatados e, ainda, pouco se conhece sobre os aspectos clínicos e radiológicos dessa condição. Objetivos: refinar o fenótipo da síndrome disostose mandibulofacial tipo Bauru; caracterizar clinicamente uma amostra de indivíduos com DMF tipo Bauru; investigar e caracterizar as alterações de mandíbula, maxila, arco zigomático e côndilo mandibular, presentes na amostra, por meio de avaliação radiológica. Pacientes estudados e métodos: foram incluídos neste estudo 11 indivíduos com diagnóstico clínico de DMF tipo Bauru. Todos os indivíduos foram submetidos à avaliação genético-clínica e, aqueles que ainda não tinham realizado TC foram submetidos à TC cone beam de face ou telerradiografia, dependendo da idade. As imagens de TC cone beam foram reconstruídas em terceira dimensão (3D) e obtidas telerradiografias em norma lateral, de face completa. Resultados: todos os indivíduos foram do gênero feminino. Levantamento da história familial foi observada em duas famílias, uma com padrão sugestivo de herança autossômica dominante e outra, sugestivo de herança autossômica recessiva Os principais achados clínicos incluíram frontal curto (63,6%), estreitamento bitemporal (90,9%), fácies alongado (63,6%), sobrancelhas arqueadas (90,9%), pálpebras superiores inclinadas para baixo (90,9%), ponte nasal alta (90,9%), hipoplasia de face média (100%), lábio inferior grosso e evertido (72,7%), micrognatia (100%), orelhas pequenas (54,5%), implantação baixa de orelhas (72,7%), orelhas posteriormente rodadas (81,8%), tragus hipoplásico (72,7%), lobo hipoplásico (72,7%) e perda auditiva condutiva (100%). A TC cone beam foi realizada em 8 dos 11 indivíduos e os principais achados observados na análise morfológica foram: assimetria facial (87,5%), órbitas assimétricas (100%), arco zigomático inclinado para baixo (100%), hipoplasia de maxila (100%), cavidade glenóide hipoplásica (62,5%), côndilos mandibulares hipoplásicos (75%), processo coronóide anômalo (37%), profundidade da incisura da mandíbula reduzida (62,5%), assimetria mandibular (100%), micrognatia e retrognatia (100%), meato acústico externo atópico (100%). Análise cefalométrica mostrou padrão de crescimento vertical (87,5%), dimensão da maxila reduzida (60%), mandíbula pequena (100%), ramo mandibular curto (100%), altura facial total reduzida (50%), altura facial ântero-inferior aumentada (70%). Conclusões: o padrão facial típico da DMF tipo Bauru incluiu: frontal curto, pálpebras superiores inclinadas para baixo, ponte nasal alta, hipoplasia de face média e de região zigomática, fissura orofacial, lábio inferior grosso e evertido e micrognatia acentuada. Radiograficamente é caracterizada por arco zigomático inclinado para baixo, hipoplasia de maxila, micrognatia e retrognatia, assimetria…
Advisors/Committee Members: Ceide, Roseli Maria Zechi.
Subjects/Keywords: Anomalia craniofacial; Craniofacial anomalies.; disostose mandibulofacial; fissura orofacial; mandibulofacial dysostosis; orofacial clefting
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Moura, P. P. (2013). Refinamento fenotípico da disostose mandibulofacial tipo Bauru. (Masters Thesis). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/61/61132/tde-12112013-145300/ ;
Chicago Manual of Style (16th Edition):
Moura, Priscila Padilha. “Refinamento fenotípico da disostose mandibulofacial tipo Bauru.” 2013. Masters Thesis, University of São Paulo. Accessed March 05, 2021.
http://www.teses.usp.br/teses/disponiveis/61/61132/tde-12112013-145300/ ;.
MLA Handbook (7th Edition):
Moura, Priscila Padilha. “Refinamento fenotípico da disostose mandibulofacial tipo Bauru.” 2013. Web. 05 Mar 2021.
Vancouver:
Moura PP. Refinamento fenotípico da disostose mandibulofacial tipo Bauru. [Internet] [Masters thesis]. University of São Paulo; 2013. [cited 2021 Mar 05].
Available from: http://www.teses.usp.br/teses/disponiveis/61/61132/tde-12112013-145300/ ;.
Council of Science Editors:
Moura PP. Refinamento fenotípico da disostose mandibulofacial tipo Bauru. [Masters Thesis]. University of São Paulo; 2013. Available from: http://www.teses.usp.br/teses/disponiveis/61/61132/tde-12112013-145300/ ;
19.
Watanabe, Maria Luiza Veloso de Almeida.
Avaliação cefalométrica da morfologia craniofacial em crianças e adolescentes HIV positivos.
Degree: Mestrado, Patologia Bucal, 2015, University of São Paulo
URL: http://www.teses.usp.br/teses/disponiveis/23/23141/tde-17062015-110134/
;
► Com cerca de 35,3 milhões de pessoas vivendo com HIV/AIDS no mundo, não foram encontrados estudos cefalométricos realizados em grupos de pacientes com HIV/AIDS e…
(more)
▼ Com cerca de 35,3 milhões de pessoas vivendo com HIV/AIDS no mundo, não foram encontrados estudos cefalométricos realizados em grupos de pacientes com HIV/AIDS e portanto não há como estimar se a doença ou seu tratamento podem influenciar o crescimento craniofacial de crianças e adolescentes soropositivos. Estudos sobre o desenvolvimento deste grupo de pacientes, que utilizam a terapia antirretroviral (TARV-HAART), comprovam que ocorrem alterações que podem afetar o crescimento normal dessa população, seja em peso e/ou altura. Assim foi feita uma pesquisa sobre a morfologia craniofacial, através da avaliação do perfil cefalométrico esquelético, de pacientes HIV positivos infectados por transmissão vertical e submetidos à terapia antirretroviral, através de um estudo com 21 pacientes HIV positivos com idade entre 6 anos a 17 anos, comparados com 21 pacientes normorreativos pareados por sexo e idade. Embora as diferenças não sejam estatisticamente significantes, encontramos na morfologia craniofacial, medidas lineares diminuídas de crianças HIV positivas, particularmente na faixa etária de 13 a 17 anos de idade, quando comparadas às crianças normorreativas.
With around 35.3 million people living with HIV/AIDS in the world, it hasn´t been found cephalometric studies performed in groups of patients with HIV/AIDS, therefore it can´t be estimated if the disease or its treatment can have influence on HIV positive children and adolescentsćraniofacial growth. Studies about the development of this group, which use HAART, have proved that there are alterations that can affect the regular growth of this population, either in terms of weight and/or height. Thus, there has been done a research about craniofacial morphology evaluating the skeletal chephalometric profile of HIV positive patients infected via vertical transmission and submitted to antiretroviral therapy, in a study with 21 HIV positive patients, ages between 6 to 17 years old, compared to 21 normoreactive patients, paired according to sex and age. Although the differences are not statistically significant, we have found in craniofacial morphology, linear measurements diminished in HIV positive children, particularly in the age range between 13 to 17 years old, when compared to normoreactive children.
Advisors/Committee Members: Ortega, Karem Lopez.
Subjects/Keywords: Adolescentes; Adolescents; AIDS; AIDS; Cefalometria; Cephalometric; Children; Craniofacial Morphology; Crianças; HIV; HIV; Morfologia craniofacial
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Watanabe, M. L. V. d. A. (2015). Avaliação cefalométrica da morfologia craniofacial em crianças e adolescentes HIV positivos. (Masters Thesis). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/23/23141/tde-17062015-110134/ ;
Chicago Manual of Style (16th Edition):
Watanabe, Maria Luiza Veloso de Almeida. “Avaliação cefalométrica da morfologia craniofacial em crianças e adolescentes HIV positivos.” 2015. Masters Thesis, University of São Paulo. Accessed March 05, 2021.
http://www.teses.usp.br/teses/disponiveis/23/23141/tde-17062015-110134/ ;.
MLA Handbook (7th Edition):
Watanabe, Maria Luiza Veloso de Almeida. “Avaliação cefalométrica da morfologia craniofacial em crianças e adolescentes HIV positivos.” 2015. Web. 05 Mar 2021.
Vancouver:
Watanabe MLVdA. Avaliação cefalométrica da morfologia craniofacial em crianças e adolescentes HIV positivos. [Internet] [Masters thesis]. University of São Paulo; 2015. [cited 2021 Mar 05].
Available from: http://www.teses.usp.br/teses/disponiveis/23/23141/tde-17062015-110134/ ;.
Council of Science Editors:
Watanabe MLVdA. Avaliação cefalométrica da morfologia craniofacial em crianças e adolescentes HIV positivos. [Masters Thesis]. University of São Paulo; 2015. Available from: http://www.teses.usp.br/teses/disponiveis/23/23141/tde-17062015-110134/ ;
20.
Ducati, Luís Gustavo.
Análise dos fatores relacionados ao desenvolvimento neuropsicológico e à aquisição de linguagem em pacientes com síndrome de Crouzon.
Degree: Mestrado, Fissuras Orofaciais, 2008, University of São Paulo
URL: http://www.teses.usp.br/teses/disponiveis/61/61132/tde-03112008-115227/
;
► Objetivo: Avaliar quais fatores são relevantes no desenvolvimento neuropsicológico e de linguagem em pacientes portadores da Síndrome de Crouzon. Modelo: Estudo transversal em pacientes com…
(more)
▼ Objetivo: Avaliar quais fatores são relevantes no desenvolvimento neuropsicológico e de linguagem em pacientes portadores da Síndrome de Crouzon. Modelo: Estudo transversal em pacientes com Síndrome de Crouzon com diagnóstico estabelecido por genética clinica, submetidos a protocolo de avaliação multidisciplinar (avaliação clínica, social, neuropsicológica, fonoaudiológica e neurorradiológica). Local: Hospital de Reabilitação de Anomalias Craniofaciais, Universidade de São Paulo (HRAC-USP), Bauru. Pacientes: Foram selecionados 10 pacientes que preencheram todos os critérios de inclusão. Todos os pacientes eram acompanhados no Ambulatório de Cirurgia Craniofacial do HRAC-USP, e foram submetidos a avaliação clínica, perfil sócio-econômico, avaliação neuropsicológica, avaliação fonoaudiológica, questionário de qualidade de vida familiar e ressonância magnética encefálica. Resultados: Houve correlação estatisticamente significante entre o desenvolvimento neuropsicológico e o diagnóstico fonoaudiológico (p=0,003). Entretanto, fatores como a realização de cirurgia craniana, alterações encontradas em neuroimagem, aspectos sócio-econômicos e qualidade de vida familiar não influenciaram no desenvolvimento neuropsicológico e de linguagem. Em relação à qualidade de vida, houve predomínio do fator 2 (pessimismo) do questionário de recursos e estresse simplificado. Conclusões: Na amostra estudada, existiu correlação entre o desenvolvimento neuropsicológico e de linguagem.
Objective: To evaluate relevant factors to the neuropsychological development and language acquisition in patients with Crouzon syndrome. Model: Transversal study of patients with Crouzon syndrome diagnosed by clinical genetics examination, who underwent a multidisciplinary team assessment (craniofacial, socioeconomic, neuroradiological, neuropsychological and language evaluations). Setting: Hospital de Reabilitação de Anomalias Craniofaciais, Universidade de São Paulo (HRAC-USP), Bauru. Participants: Ten patients with Crouzon syndrome accompanied by the craniofacial surgery team of the HRAC-USP, who fulfilled all the inclusion criteria, and underwent clinical, socioeconomic, neuropsychological, language, quality of life and neuroradiological (brain magnetic resonance imaging) assessments. Results: Neuropsychological development and language performance had a statistically significant correlation (p=0,003). However, variables as craniofacial surgery, neuroimaging abnormalities, socioeconomic and quality of life findings did not show any relationship with either neuropsychological or language development. Regarding to quality of life, there was a higher prevalence of pessimism (factor II of the short form of the questionnaire on resources and stress). Conclusions: In the present study, we found a correlation between neuropsychological development and language acquisition.
Advisors/Committee Members: Fernandes, Adriano Yacubian.
Subjects/Keywords: Craniofacial dysostosis; Disostose craniofacial; language; linguagem; neuropsicologia; neuropsychology; qualidade de vida; quality of life
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Ducati, L. G. (2008). Análise dos fatores relacionados ao desenvolvimento neuropsicológico e à aquisição de linguagem em pacientes com síndrome de Crouzon. (Masters Thesis). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/61/61132/tde-03112008-115227/ ;
Chicago Manual of Style (16th Edition):
Ducati, Luís Gustavo. “Análise dos fatores relacionados ao desenvolvimento neuropsicológico e à aquisição de linguagem em pacientes com síndrome de Crouzon.” 2008. Masters Thesis, University of São Paulo. Accessed March 05, 2021.
http://www.teses.usp.br/teses/disponiveis/61/61132/tde-03112008-115227/ ;.
MLA Handbook (7th Edition):
Ducati, Luís Gustavo. “Análise dos fatores relacionados ao desenvolvimento neuropsicológico e à aquisição de linguagem em pacientes com síndrome de Crouzon.” 2008. Web. 05 Mar 2021.
Vancouver:
Ducati LG. Análise dos fatores relacionados ao desenvolvimento neuropsicológico e à aquisição de linguagem em pacientes com síndrome de Crouzon. [Internet] [Masters thesis]. University of São Paulo; 2008. [cited 2021 Mar 05].
Available from: http://www.teses.usp.br/teses/disponiveis/61/61132/tde-03112008-115227/ ;.
Council of Science Editors:
Ducati LG. Análise dos fatores relacionados ao desenvolvimento neuropsicológico e à aquisição de linguagem em pacientes com síndrome de Crouzon. [Masters Thesis]. University of São Paulo; 2008. Available from: http://www.teses.usp.br/teses/disponiveis/61/61132/tde-03112008-115227/ ;
21.
Daré, Letícia Rossi.
Efeito do β-hidroxi-β-metilbutirato sobre os músculos da mastigação e desenvolvimento e crescimento craniofacial de ratos.
Degree: Mestrado, Estomatologia e Biologia Oral, 2013, University of São Paulo
URL: http://www.teses.usp.br/teses/disponiveis/25/25149/tde-23042014-091455/
;
► Atualmente está aumentando o número de pessoas que usam suplementos nutricionais com a finalidade de obter melhores resultados nas suas atividades esportivas, perda de gordura,…
(more)
▼ Atualmente está aumentando o número de pessoas que usam suplementos nutricionais com a finalidade de obter melhores resultados nas suas atividades esportivas, perda de gordura, ganhos de massa muscular, ou na plasticidade do corpo. Tal fato merece atenção porque muito pouco é conhecido sobre a segurança ou eficácia destes produtos, e apenas 14% dos usuários buscam orientações com profissional da saúde sobre o uso destas substâncias. Dos mais de 200 suplementos que prometem estes efeitos apenas as suplementações de creatina HMB produzem os resultados prometidos, e o Comitê Olímpico qualifica o uso do HMB como legal. Embora a literatura atual mostre os benefícios no uso da suplementação com HMB, são poucas as informações sobre o seu efeito na morfofisiologia das fibras musculares como, por exemplo, o perfil histoenzimológico e a área dos diferentes tipos de fibras musculares. Baseado nestas informações pensou-se na realização desde trabalho para verificar se o uso de HMB provoca alterações morfológicas e histoenzimológicas nas fibras musculares dos músculos da mastigação; se estes efeitos alterariam o desenvolvimento e crescimento do esqueleto craniofacial; e se os efeitos sobre os componentes do sistema estomatognático seriam semelhantes nos indivíduos ambos os gêneros. Para realização deste estudo foram utilizados 58 ratos com idade de 60 dias, 29 animais de cada gênero, distribuídos nos seguintes grupos: Grupo Controle Inicial (GCI) que foram sacrificados no inicio do experimento; Grupo Controle Placebo (GCP) que receberam o mesmo volume do veículo do grupo experimental, e alimentação ad libitum; Grupo Experimental (GE) que receberam diariamente 0,3g/kg de HMB, por meio de gavagem e mesma quantidade de alimentos que GCP consumiu no dia anterior; Grupo Experimental Ad libitum (GEA) que receberam a mesma dose da droga, porém tiveram alimentação ad libitum. Após o tratamento, foram retiradas amostras dos músculos digástrico (ventre anterior) e masseter (porção superficial), para análise histoenzimologica (m-ATPAse com pré-incubações ácida e alcalina) e retirada do esqueleto cefálico para tomadas das medidas craniométricas. Os dados obtidos foram submetidos a tratamento estatístico. Os resultados permitiram concluir que: o uso diário de 0,3g/kg de HMB, por quatro semanas: a) não provocou alterações morfológicas e histoenzimológicas nas fibras muscular dos músculos da mastigação; b) os resultados foram semelhantes entre os músculos elevadores e abaixadores da mandíbula; c) não provoca alterações no desenvolvimento e crescimento do esqueleto craniofacial; d) a falta de resultados positivos de alterações nos músculos da mastigação e crescimento craniofacial, sugere existiram um relação entre eles; e) os resultados sobre os componentes do sistema estomatognático foram semelhantes nos indivíduos ambos os gêneros.
Nowadays is increasing the number of people who use nutritional supplements in order to achieve better results in their sports, fat loss, muscle gains, or the plasticity of the body. This deserves attention…
Advisors/Committee Members: Andreo, Jesus Carlos.
Subjects/Keywords: Craniofacial growth; Crescimento craniofacial; HMB; HMB; Masticatory muscles; Músculos mastigatórios; Ratos; Rats
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Daré, L. R. (2013). Efeito do β-hidroxi-β-metilbutirato sobre os músculos da mastigação e desenvolvimento e crescimento craniofacial de ratos. (Masters Thesis). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/25/25149/tde-23042014-091455/ ;
Chicago Manual of Style (16th Edition):
Daré, Letícia Rossi. “Efeito do β-hidroxi-β-metilbutirato sobre os músculos da mastigação e desenvolvimento e crescimento craniofacial de ratos.” 2013. Masters Thesis, University of São Paulo. Accessed March 05, 2021.
http://www.teses.usp.br/teses/disponiveis/25/25149/tde-23042014-091455/ ;.
MLA Handbook (7th Edition):
Daré, Letícia Rossi. “Efeito do β-hidroxi-β-metilbutirato sobre os músculos da mastigação e desenvolvimento e crescimento craniofacial de ratos.” 2013. Web. 05 Mar 2021.
Vancouver:
Daré LR. Efeito do β-hidroxi-β-metilbutirato sobre os músculos da mastigação e desenvolvimento e crescimento craniofacial de ratos. [Internet] [Masters thesis]. University of São Paulo; 2013. [cited 2021 Mar 05].
Available from: http://www.teses.usp.br/teses/disponiveis/25/25149/tde-23042014-091455/ ;.
Council of Science Editors:
Daré LR. Efeito do β-hidroxi-β-metilbutirato sobre os músculos da mastigação e desenvolvimento e crescimento craniofacial de ratos. [Masters Thesis]. University of São Paulo; 2013. Available from: http://www.teses.usp.br/teses/disponiveis/25/25149/tde-23042014-091455/ ;

Univerzitet u Beogradu
22.
Juloski, Jovana T., 1981-.
Dinamika rasta kraniofacijalnog kompleksa osoba sa Tarner
sindromom.
Degree: Stomatološki fakultet, 2014, Univerzitet u Beogradu
URL: https://fedorabg.bg.ac.rs/fedora/get/o:7932/bdef:Content/get
► stomatologija - ortopedija vilica (ortodoncija)/dentistry - dentofacial orthopaedics (orthodontics)
Morfologija kraniofacijalnog kompleksa osoba sa Tarner sindromom je podrobno ispitana, dok su podaci o dinamici rasta…
(more)
▼ stomatologija - ortopedija vilica
(ortodoncija)/dentistry - dentofacial orthopaedics
(orthodontics)
Morfologija kraniofacijalnog kompleksa osoba sa
Tarner sindromom je podrobno ispitana, dok su podaci o dinamici
rasta oskudni u literaturi. Kako je hormon rasta sve više
zastupljen u lečenju ovih pacijentkinja, javila se potreba za
ispitivanjem morfologije i rasta kraniofacijalnog kompleksa osoba
sa Tarner sindromom koje primaju hormon rasta. Ciljevi ove
disertacije bili su da se ispita da li se i u kojoj meri
morfologija i rast kraniofacijalnog kompleksa devojčica sa Tarner
sindromom koje primaju hormon rasta razlikuje od zdravih devojčica.
Razlike u morfologiji kraniofacijalnog kompleksa ustanovljene su na
osnovu rendgen-kefalometrijske analize 21-og profilnog snimka glave
devojčica sa Tarner sindromom koje primaju hormon rasta i 46
snimaka zdravih devojčica. Kako bi se ispitao rast kraniofacijalnog
kompleksa svi snimci su, na osnovu stadijuma skeletne zrelosti
vratnih pršljenova, podeljeni u dve podgrupe („pre intenzivnog
rasta“ i „intenzivnog rasta“). Dinamika rasta ispitana je na osnovu
promena između podgrupa kao i rezultata superponiranja 10 parova
snimaka glave devojčica ispitivane grupe. Morfologija
kraniofacijalnog kompleksa devojčica sa Tarner sindromom koje
primaju hormon rasta se razlikovala od morfologije zdravih po
bimaksilarnom retrognatizmu, nedovoljno razvijenom telu i
prerazvijenoj grani donje vilice i većim visinama lica. Do perioda
intenzivnog rasta nisu uočene razlike u rastu kraniofacijalnog
kompleksa između devojčica sa Tarner sindromom koje primaju hormon
rasta i zdravih devojčica. Tokom perioda intenzivnog rasta, razlike
u dinamici i intenzitetu rasta dovele su do promena u morfologiji
kraniofacijalnog kompleksa. Ustanovljeno je da je kod devojčica sa
Tarner sindromom pravac rasta vilica takav da dovodi do
bimaksilarnog retrognatizma i da postoji razlika u intenzitetu
rasta vilica i visina lica. Nije ustanovljena razlika u dinamici i
intenzitetu rasta ostalih struktura. Rast kraniofacijalnog
kompleksa devojčica sa Tarner sindromom koje primaju hormon rasta
se, po dinamici i intenzitetu, u određenoj meri razlikuje od rasta
zdravih osoba što uzrokuje karakterističnu morfologiju
kraniofacijalnog kompleksa.
Advisors/Committee Members: Glišić, Branislav, 1962-.
Subjects/Keywords: Turner syndrome; craniofacial complex morphology;
craniofacial growth; growth rate and pattern; growth
hormone
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Juloski, Jovana T., 1. (2014). Dinamika rasta kraniofacijalnog kompleksa osoba sa Tarner
sindromom. (Thesis). Univerzitet u Beogradu. Retrieved from https://fedorabg.bg.ac.rs/fedora/get/o:7932/bdef:Content/get
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Juloski, Jovana T., 1981-. “Dinamika rasta kraniofacijalnog kompleksa osoba sa Tarner
sindromom.” 2014. Thesis, Univerzitet u Beogradu. Accessed March 05, 2021.
https://fedorabg.bg.ac.rs/fedora/get/o:7932/bdef:Content/get.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Juloski, Jovana T., 1981-. “Dinamika rasta kraniofacijalnog kompleksa osoba sa Tarner
sindromom.” 2014. Web. 05 Mar 2021.
Vancouver:
Juloski, Jovana T. 1. Dinamika rasta kraniofacijalnog kompleksa osoba sa Tarner
sindromom. [Internet] [Thesis]. Univerzitet u Beogradu; 2014. [cited 2021 Mar 05].
Available from: https://fedorabg.bg.ac.rs/fedora/get/o:7932/bdef:Content/get.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Juloski, Jovana T. 1. Dinamika rasta kraniofacijalnog kompleksa osoba sa Tarner
sindromom. [Thesis]. Univerzitet u Beogradu; 2014. Available from: https://fedorabg.bg.ac.rs/fedora/get/o:7932/bdef:Content/get
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Pretoria
23.
Briers, N.
A morphological
and biometric study of the facial characteristics of two South
African childhood populations at different age levels.
Degree: PhD, Anatomy, 2015, University of Pretoria
URL: http://hdl.handle.net/2263/45942
► Positive identification can be problematic if fingerprinting, DNA, dental history, etc. are no longer available. This may be possible through techniques such as facial approximation,…
(more)
▼ Positive identification can be problematic if
fingerprinting, DNA, dental history, etc. are no longer available.
This may be possible through techniques such as facial
approximation, but any form of
craniofacial identification requires
intimate knowledge of human
craniofacial anatomy. Where children
are involved,
craniofacial changes due to facial growth further
complicate matters and require knowledge of tissue thickness and
variation in facial shapes. These have hardly been studied in
children of African descent.
The aims of this study were to
provide data on tissue thickness and
craniofacial proportions of
South African Black and Coloured children and to document the
lateral profile shape changes between the ages of 6 and 13 years.
Tissue thickness was measured using cephalograms of South African
children (n = 388). After digitizing the images, tissue thickness
measurements were taken at 11 mid-facial landmarks from each image
using the iTEM measuring program.
Craniofacial proportions were
assessed through assessing standardized anterior and lateral facial
photographs of 1749 children. Measurements of facial features were
taken using iTEM, from which 28 standard facial indices were
calculated. For both tissue thickness and
craniofacial indices
comparisons between groups per age, sex and ancestry were
statistically analyzed. In addition, geometric morphometrics were
used to describe lateral facial shape changes and differences age,
sex and ancestry (n = 800).
The results showed that tissue
thickness differences at lower face landmarks are more pronounced
in age groups per ancestry as opposed to differences per age and
sex. Facial profile per facial shape, class and ancestry showed
differences at all landmarks.
Craniofacial indices indicated that
Coloured children have wider heads, foreheads and faces compared to
Black children. The height of the nose and lower lip is longer in
Coloured children compared to Black children. In Coloured children,
mandibular height and lower face height is shorter in relation to
total face height. Males have wider heads, foreheads, mandibles and
faces compared to females. The degree of prognathism is dictated by
ancestry and to a lesser extent by age and sex as findings showed
that maxillary prognathism was more prominent in Black children,
while mandibular prognathism were more pronounced in male children.
South Africans have a relative concave lateral facial profile due
to the maxilla and mandible being more prognathic than in North
American children. Differences in lateral face shape between
children of various ages, sexes and ancestral groups were
visualized through the relative displacement of landmarks related
to the forehead and lower face. The resultant differences in
lateral facial profile can assist in more accurate estimation of
age and ancestry of unknown children. This research created
reference datasets for tissue thickness and
craniofacial indices of
South African children of Black and Coloured ancestry per age and
sex that will be useful in the diagnosis of facial…
Advisors/Committee Members: Steyn, Maryna (advisor).
Subjects/Keywords: UCTD; Craniofacial
reconstruction; Craniofacial
approximation; Facial
growth; Tissue
thickness; Geometric
morphometrics; South African
population
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Briers, N. (2015). A morphological
and biometric study of the facial characteristics of two South
African childhood populations at different age levels. (Doctoral Dissertation). University of Pretoria. Retrieved from http://hdl.handle.net/2263/45942
Chicago Manual of Style (16th Edition):
Briers, N. “A morphological
and biometric study of the facial characteristics of two South
African childhood populations at different age levels.” 2015. Doctoral Dissertation, University of Pretoria. Accessed March 05, 2021.
http://hdl.handle.net/2263/45942.
MLA Handbook (7th Edition):
Briers, N. “A morphological
and biometric study of the facial characteristics of two South
African childhood populations at different age levels.” 2015. Web. 05 Mar 2021.
Vancouver:
Briers N. A morphological
and biometric study of the facial characteristics of two South
African childhood populations at different age levels. [Internet] [Doctoral dissertation]. University of Pretoria; 2015. [cited 2021 Mar 05].
Available from: http://hdl.handle.net/2263/45942.
Council of Science Editors:
Briers N. A morphological
and biometric study of the facial characteristics of two South
African childhood populations at different age levels. [Doctoral Dissertation]. University of Pretoria; 2015. Available from: http://hdl.handle.net/2263/45942

The Ohio State University
24.
Lloyd, Brandon R.
Comparison of Bone Marrow Mesenchymal Stem Cells from Limb
and Jaw Bones.
Degree: MS, Dentistry, 2016, The Ohio State University
URL: http://rave.ohiolink.edu/etdc/view?acc_num=osu1458678153
► Objectives: Bone marrow mesenchymal stem cells (BM-MSCs) from limb bones have demonstrated promises in regenerating craniofacial bones; yet little is known about the potential of…
(more)
▼ Objectives: Bone marrow mesenchymal stem cells
(BM-MSCs) from limb bones have demonstrated promises in
regenerating
craniofacial bones; yet little is known about the
potential of BM-MSCs from
craniofacial bones. This study compared
BM-MSCs isolated from limb and
craniofacial bones in a commonly
used preclinical large animal model, the pig. Methods: Bone marrow
was aspirated from the tibia and mandible (symphysis) of
4-month-old pigs (n=4). Subsequently, BM-MSCs were isolated,
expanded and confirmed by flow cytometry. To assess cell
proliferation, cell doubling times were calculated from serial cell
number counts over 2 weeks. Total mRNA was extracted from freshly
isolated BM-MSCs and analyzed for gene expression using an
Affymetrix GeneChip porcine genome array, followed by real-time
RT-PCR for validation. Osteogenic capacity was assessed by
quantifying alkaline phosphatase activity. Using
temperature-responsive culturing plates, the abilities of BM-MSCs
to form multi-layer cell sheets (for future in-vivo
transplantation), along with cell viability and morphology, were
evaluated by fluorescent labeling and histological staining.
Results: BM-MSCs from both locations expressed MSC markers but not
hematopoietic markers. Mandibular BM-MSCs proliferated
significantly faster than tibial BM-MSCs (median cell doubling
times: 2.25 vs. 2.80 days, Mann-Whitney U test, p<0.01). Without
any osteogenic induction, mandibular BM-MSC alkaline phosphatase
activities were 3.3-fold (factorial ANOVA, p<0.001) to those of
tibial BM-MSCs. Microarray analysis on one hand confirmed that
overall mandibular and tibial BM-MSC gene expressions are highly
correlated with each other and genes related to osteogenesis and
angiogenesis were strongly expressed, and on the other hand
revealed that there were several dozen genes which were indeed
differentially expressed between mandibular and tibial BM-MSCs.
They include cranial neural crest-related genes nestin (1.23-fold)
and BMP-4 (1.79-fold), which were higher in mandibular BM-MSCs
(ANOVA, p<0.05), a trend also confirmed by real-time RT-PCR
tests. Three-layer cell sheets were successfully fabricated using
both sources of BM-MSCs, but mandibular BM-MSCs required lower
initial seeding density and had fewer dead cells than tibial
BM-MSCs (3.13% vs. 10.25%, t-test, p<0.05). Conclusions: These
data indicate that mandibular BM-MSCs may possess a greater
potential than limb bone BM-MSCs for
craniofacial bone
regeneration.
Advisors/Committee Members: Sun, Zongyang (Advisor).
Subjects/Keywords: Dentistry; marrow stromal cells, microarray, craniofacial bone
regeneration, BMP-4, osteogenic, craniofacial bone marrow
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Lloyd, B. R. (2016). Comparison of Bone Marrow Mesenchymal Stem Cells from Limb
and Jaw Bones. (Masters Thesis). The Ohio State University. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=osu1458678153
Chicago Manual of Style (16th Edition):
Lloyd, Brandon R. “Comparison of Bone Marrow Mesenchymal Stem Cells from Limb
and Jaw Bones.” 2016. Masters Thesis, The Ohio State University. Accessed March 05, 2021.
http://rave.ohiolink.edu/etdc/view?acc_num=osu1458678153.
MLA Handbook (7th Edition):
Lloyd, Brandon R. “Comparison of Bone Marrow Mesenchymal Stem Cells from Limb
and Jaw Bones.” 2016. Web. 05 Mar 2021.
Vancouver:
Lloyd BR. Comparison of Bone Marrow Mesenchymal Stem Cells from Limb
and Jaw Bones. [Internet] [Masters thesis]. The Ohio State University; 2016. [cited 2021 Mar 05].
Available from: http://rave.ohiolink.edu/etdc/view?acc_num=osu1458678153.
Council of Science Editors:
Lloyd BR. Comparison of Bone Marrow Mesenchymal Stem Cells from Limb
and Jaw Bones. [Masters Thesis]. The Ohio State University; 2016. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=osu1458678153
25.
Rosalya Maria Coura.
Correlação entre respiração buconasal e alterações anatômicas e funcionais do complexo craniofacial.
Degree: 2010, Universidade Federal da Paraíba
URL: http://bdtd.biblioteca.ufpb.br/tde_busca/arquivo.php?codArquivo=848
► Este estudo objetivou correlacionar a respiração buconasal com as alterações anatômicas e funcionais do complexo craniofacial, através de questionários, radiografias e testes clínicos rápidos. Tratou-se…
(more)
▼ Este estudo objetivou correlacionar a respiração buconasal com as alterações anatômicas e funcionais do complexo craniofacial, através de questionários, radiografias e testes clínicos rápidos. Tratou-se de um estudo analítico do tipo observacional caso-controle em pesquisa quantitativa, desenvolvido no município de Sousa PB. Na pesquisa foram incluídas 143 crianças e adolescentes de ambos os gêneros, dentro de um universo de 887 alunos com faixa etária entre 6 e 14 anos de idade, divididos em dois grupos, sendo um grupo controle os respiradores nasais e um grupo experimental os respiradores buconasais. Os resultados demonstraram uma prevalência de 51% de respiradores buconasais na amostra, existindo associação significativa entre a respiração buconasal e as variáveis deglutição atípica, ausência de selamento labial, fonação alterada, hipotonicidade labial, palato duro profundo, tonsilas palatinas hipertróficas, falta de ar, cansaço rápido, diminuição do paladar, halitose, olheiras, espirros freqüentes e saliva ao falar, porém quanto aos ângulos goníacos total, superior e inferior observou-se que as médias foram aproximadas entre os dois grupos.
This research aimed to correlate the oral nasal breathing with the anatomic and functional alterations of the craniofacial complex by means of questionnaires, x-rays and fast clinical tests. It was an analytical study of the observational case control type in quantitative research, carried out in the town of Sousa-PB. In the research, one hundred and forty-three children and teenagers, from both genders, were included as part of a universe of 887 students, varying from 06 up to 14 years old, which were divided into two groups. One of them is a control group: nasal breathers whereas the other one is an experimental group of oral nasal breathers. The results showed a prevalence of 51% of oral nasal breathers in the sample, existing, thus, a meaningful association between oral nasal breathing and the variables related to atypical swallowing, absence of labial sealing, altered phonation, labial hypotonicity, deep hard palate, hypertrophic palatine tonsils, breathless, fast fatigue, taste decreasing, halitosis, dark circle under the eyes, frequent sneezing and saliva while speaking. However, as concern all upper and lower goniac angles, it was observed that the media were approximate between the two groups.
Advisors/Committee Members: Cláudia Roberta Leite Vieira de Figueiredo.
Subjects/Keywords: Respiração bucal; Crescimento e desenvolvimento craniofacial; Sistema estomatognático; ODONTOLOGIA; Mouth breathing; Craniofacial growth and development; Stomatognathic system
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Coura, R. M. (2010). Correlação entre respiração buconasal e alterações anatômicas e funcionais do complexo craniofacial. (Thesis). Universidade Federal da Paraíba. Retrieved from http://bdtd.biblioteca.ufpb.br/tde_busca/arquivo.php?codArquivo=848
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Coura, Rosalya Maria. “Correlação entre respiração buconasal e alterações anatômicas e funcionais do complexo craniofacial.” 2010. Thesis, Universidade Federal da Paraíba. Accessed March 05, 2021.
http://bdtd.biblioteca.ufpb.br/tde_busca/arquivo.php?codArquivo=848.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Coura, Rosalya Maria. “Correlação entre respiração buconasal e alterações anatômicas e funcionais do complexo craniofacial.” 2010. Web. 05 Mar 2021.
Vancouver:
Coura RM. Correlação entre respiração buconasal e alterações anatômicas e funcionais do complexo craniofacial. [Internet] [Thesis]. Universidade Federal da Paraíba; 2010. [cited 2021 Mar 05].
Available from: http://bdtd.biblioteca.ufpb.br/tde_busca/arquivo.php?codArquivo=848.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Coura RM. Correlação entre respiração buconasal e alterações anatômicas e funcionais do complexo craniofacial. [Thesis]. Universidade Federal da Paraíba; 2010. Available from: http://bdtd.biblioteca.ufpb.br/tde_busca/arquivo.php?codArquivo=848
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
26.
Yogi, Helena Emiko Tunouti.
Morfologia craniofacial e sua associação com o comprometimento funcional em adolescentes com paralisia cerebral.
Degree: Mestrado, Odontopediatria, 2014, University of São Paulo
URL: http://www.teses.usp.br/teses/disponiveis/23/23132/tde-28032014-191915/
;
► Este estudo objetivou aprofundar o conhecimento sobre a morfologia óssea craniofacial de jovens com Paralisia Cerebral, e associá-la ao comprometimento funcional geral e a função…
(more)
▼ Este estudo objetivou aprofundar o conhecimento sobre a morfologia óssea craniofacial de jovens com Paralisia Cerebral, e associá-la ao comprometimento funcional geral e a função motora orofacial. Utilizamos uma amostra pareada por gênero e idade, constituída de 21 adolescentes com Paralisia Cerebral (GE) com idade média de 14,7(2,6) anos para o gênero feminino e 13,9(2,8) anos para o gênero masculino, e 22 adolescentes normorreativos (GC) com idade média de 14,6(2,6) anos para o gênero feminino e 14,8 (3,8) anos para o gênero masculino. Foram realizadas análises das imagens obtidas por Tomografia Computadorizada Feixe Cônico e software OsiriX, através da mensuração de medidas lineares e angulares. A avaliação da função motora geral foi dada pela aplicação do instrumento Gross Motor Functional Classification System (GMFCS). O instrumento para avaliação da motricidade oral aplicado neste estudo foi o OMAS (Oral Motor Assessment Scale). Quando comparado os grupos estudo e controle, as medidas que exibiram valores estatisticamente significantes foram Co-Pg (p=0,060), ENA-N (p=0,2), N-Me (p=0,088), N.A.Pg (p=0,04) e S.N.B (p=0,11). O GE apresentou uma tendência de perfil mais convexo, indicado pelo ângulo N.A.Pg, menor do que no GC (GE:168,48 (8,05)/GC:172,77(5,21)). A medida Co-Pg menor (GE:106,36(6,08)/GC:107,94(9,45)), analisada juntamente com o ângulo S.N.B menor (GE:79,69(4,24)/GC:81,21(6,33)), indicam a mandíbula ligeiramente menor e mais retruída nos adolescentes com PC em relação ao GC. A medida N-B (p=0,035) foi estatisticamente significante e inversamente proporcional ao OMAS. Não houve relação estatisticamente significante entre o comprometimento motor geral e qualquer uma das medidas angulares e lineares no GE. Podemos concluir que a morfologia craniofacial em adolescentes com PC é diversa à de adolescentes normorreativos em algumas medidas, que não houve associação entre comprometimento motor geral e crescimento craniofacial de adolescentes com a PC e que a função motora orofacial de menor score está associada a um rosto mais longo.
This study aimed to deepen understanding of the craniofacial bone morphology of young people with cerebral palsy, and associate it to the general functional impairment and the orofacial motor function. We use a matched sample by gender and age , consisting of 21 adolescents with cerebral palsy (SG) , with a mean age of 14.7 years (2.6) for females and 13.9 years (2.8) for males , and a control group (CG), composed of 23 normoreactive adolescents with a mean age of 14.6 years (2.6) for females and 14.8 years (3.8) for males . Analysis of images obtained by CT Cone Beam and OsiriX software were performed, through the measurement of some linear and angular measurements. The evaluation of overall motor function was given by application of the instrument Gross Motor Functional Classification System (GMFCS). The instrument to evaluate oral motor applied in this study was the OMAS (Oral Motor Assessment Scale). When comparing the study and control groups, the measures showed…
Advisors/Committee Members: Ciamponi, Ana Lidia.
Subjects/Keywords: Cefalometria; Cephalometric; Cerebral Palsy; Cone beam computerized tomography; Craniofacial Morphology; Morfologia Craniofacial; Paralisia Cerebral; Tomografia computadorizada por feixe cônico
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Yogi, H. E. T. (2014). Morfologia craniofacial e sua associação com o comprometimento funcional em adolescentes com paralisia cerebral. (Masters Thesis). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/23/23132/tde-28032014-191915/ ;
Chicago Manual of Style (16th Edition):
Yogi, Helena Emiko Tunouti. “Morfologia craniofacial e sua associação com o comprometimento funcional em adolescentes com paralisia cerebral.” 2014. Masters Thesis, University of São Paulo. Accessed March 05, 2021.
http://www.teses.usp.br/teses/disponiveis/23/23132/tde-28032014-191915/ ;.
MLA Handbook (7th Edition):
Yogi, Helena Emiko Tunouti. “Morfologia craniofacial e sua associação com o comprometimento funcional em adolescentes com paralisia cerebral.” 2014. Web. 05 Mar 2021.
Vancouver:
Yogi HET. Morfologia craniofacial e sua associação com o comprometimento funcional em adolescentes com paralisia cerebral. [Internet] [Masters thesis]. University of São Paulo; 2014. [cited 2021 Mar 05].
Available from: http://www.teses.usp.br/teses/disponiveis/23/23132/tde-28032014-191915/ ;.
Council of Science Editors:
Yogi HET. Morfologia craniofacial e sua associação com o comprometimento funcional em adolescentes com paralisia cerebral. [Masters Thesis]. University of São Paulo; 2014. Available from: http://www.teses.usp.br/teses/disponiveis/23/23132/tde-28032014-191915/ ;
27.
Alves, Ana Paula Pereira Pinheiro.
Análise comparativa da antopometria facial entre pais de crianças portadoras de fissuras labiopalatinas e indivíduos sem história familiar de fissuras.
Degree: Mestrado, Prótese Buco-Maxilo-Facial, 2008, University of São Paulo
URL: http://www.teses.usp.br/teses/disponiveis/23/23144/tde-16092008-163644/
;
► Estudos investigativos sobre a influência da hereditariedade nas fissuras orofaciais têm sugerido que indivíduos não-afetados com filhos portadores de fissura labiopalatina apresentam morfologia craniofacial distinta…
(more)
▼ Estudos investigativos sobre a influência da hereditariedade nas fissuras orofaciais têm sugerido que indivíduos não-afetados com filhos portadores de fissura labiopalatina apresentam morfologia craniofacial distinta da população geral. O objetivo desta pesquisa foi, por meio de antropometria direta da face, estudar as dimensões faciais dos pais de fissurados em relação a indivíduos sem histórico familiar de fissura, com a finalidade de determinar características faciais que possam inferir uma predisposição à fissura. A amostra foi constituída por 244 indivíduos leucodermas, com média de idade de 34,1 anos, sendo 50 pais e 94 mães de crianças com fissura de lábio com ou sem envolvimento do palato, registrados na Faculdade de Odontologia da Universidade de São Paulo, formando o grupo de estudo, que foi subdividido em grupo pais, grupo mães e grupo casal; e 50 homens e 50 mulheres com ausência de história familiar de anomalias craniofaciais, compondo o grupo controle. Após a marcação de pontos antropométricos na face, foram realizadas 38 medidas antropométricas, correspondendo às dimensões faciais de altura, largura e profundidade, com auxílio de paquímetro digital e compasso facial. Para a análise estatística foi utilizado o teste t de Student com correção de Levene para igualdade de variâncias. Os resultados estatisticamente significantes, para o grupo pais, foram: largura da testa; largura da face e distâncias inter-orbital interna e externa menores, enquanto que a largura da base do nariz, a altura do perfil inferior e a profundidade da mandíbula do lado esquerdo foram maiores. No grupo mães, a distância pupila-linha média lado direito, a largura da base do nariz, a largura do nariz, a largura anatômica do nariz, a largura da columela, a altura do terço superior da face e a profundidade da mandíbula do lado esquerdo apresentaram-se maiores. Os resultados do grupo casal foram pouco consistentes porque reproduziram os registrados nos subgrupos individuais. Embora diversas medidas tenham mostrado diferenças entre o grupo de estudo e o controle, apenas a largura da base do nariz e a profundidade da mandíbula do lado esquerdo se apresentam com as dimensões aumentadas nas respectivas subdivisões: pais, mães e casal. Concluiu-se que, pais e mães de crianças portadoras de fissuras labiopalatinas apresentam morfologia craniofacial distinta em relação à população geral; entretanto, não foi possível definir um padrão facial característico.
Recent studies concerning the influence of inheritance in orofacial clefts suggest that non-affected parents of children that present cleft lip and palate show distinctive craniofacial morphology compared to the overall population. The main objective of this research was to analyze and compare the facial dimensions of non-affected parents of affected children and individuals with no history of clefting in the family. The method used was the direct facial anthropometry, since it can determine facial characteristics that may be related to predisposition to cleft. The sample used comprised…
Advisors/Committee Members: Andre, Marcia.
Subjects/Keywords: Antropometria Facial; Cleft lip and palate; Craniofacial Morphology; Facial Anthropometry; Fissura Labiopalatina; Morfologia Craniofacial; Pais; Parents
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Alves, A. P. P. P. (2008). Análise comparativa da antopometria facial entre pais de crianças portadoras de fissuras labiopalatinas e indivíduos sem história familiar de fissuras. (Masters Thesis). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/23/23144/tde-16092008-163644/ ;
Chicago Manual of Style (16th Edition):
Alves, Ana Paula Pereira Pinheiro. “Análise comparativa da antopometria facial entre pais de crianças portadoras de fissuras labiopalatinas e indivíduos sem história familiar de fissuras.” 2008. Masters Thesis, University of São Paulo. Accessed March 05, 2021.
http://www.teses.usp.br/teses/disponiveis/23/23144/tde-16092008-163644/ ;.
MLA Handbook (7th Edition):
Alves, Ana Paula Pereira Pinheiro. “Análise comparativa da antopometria facial entre pais de crianças portadoras de fissuras labiopalatinas e indivíduos sem história familiar de fissuras.” 2008. Web. 05 Mar 2021.
Vancouver:
Alves APPP. Análise comparativa da antopometria facial entre pais de crianças portadoras de fissuras labiopalatinas e indivíduos sem história familiar de fissuras. [Internet] [Masters thesis]. University of São Paulo; 2008. [cited 2021 Mar 05].
Available from: http://www.teses.usp.br/teses/disponiveis/23/23144/tde-16092008-163644/ ;.
Council of Science Editors:
Alves APPP. Análise comparativa da antopometria facial entre pais de crianças portadoras de fissuras labiopalatinas e indivíduos sem história familiar de fissuras. [Masters Thesis]. University of São Paulo; 2008. Available from: http://www.teses.usp.br/teses/disponiveis/23/23144/tde-16092008-163644/ ;
28.
Silva, Fabiane Louly Baptista Santos.
Avaliação cefalométrica do crescimento craniofacial em crianças leucodermas brasileiras, com má oclusão de Classe II durante as fases de crescimento determinadas pela maturação das vértebras cervicais.
Degree: PhD, Ortodontia, 2010, University of São Paulo
URL: http://www.teses.usp.br/teses/disponiveis/25/25134/tde-18082010-102325/
;
► As características do crescimento craniofacial dos indivíduos portadores de má oclusão de Classe II na fase de crescimento, são de intenso interesse dos ortodontistas por…
(more)
▼ As características do crescimento
craniofacial dos indivíduos portadores de má oclusão de Classe II na fase de crescimento, são de intenso interesse dos ortodontistas por esta má oclusão representar uma alta porcentagem dos casos em tratamento nos consultórios. Esta investigação objetivou estudar cefalométrica e comparativamente o crescimento
craniofacial em crianças leucodermas portadoras de má oclusão de Classe II e de Oclusão Normal. Foram utilizadas 148 telerradiografias em norma lateral de 78 meninos e 70 meninas, faixa etária dos 7 aos 12 anos, portadores de má oclusão de Classe II, e 60 telerradiografias em norma lateral de 30 meninas e 30 meninos com Oclusão Normal. As amostras foram divididas considerando-se o estágio da maturação das vértebras cervicais pelo método de Hassel e Farman(HASSEL; FARMAN 1995), estando os grupos nos níveis Iniciação(I), Aceleração (A) e Transição (T) do desenvolvimento esquelético. Foram utilizadas as grandezas SNA, A-Nperp e Co-A para avaliar o componente maxilar; SNB, P-Nperp, Co-Gn, Co-Go e Go-Gn para o componente mandibular; ANB representou a relação maxilomandibular; SN.GoGn, FMA, NS.Gn, BaN.PtGn e ENA-Me para o componente vertical, e o ângulo da base do crânio representado por NS.Ba. O teste t independente foi aplicado: entre os grupos para verificar a precocidade dos índices entre os gêneros; em cada grupo e índice nos gêneros feminino e no masculino; na comparação entre os grupos em cada índice nos gêneros feminino e no masculino; na comparação entre os grupos na fase IT (Iniciação Transição) em cada gênero. Os resultados mostraram: precocidade do índice A (aceleração) no gênero feminino do grupo de Classe II. Na comparação entre os gêneros do grupo de Classe II no nível I, as medidas de Co-A, Co-Gn, Go- Gn e ENA-Me foram maiores no gênero masculino, que também apresentaram significância estatística no nível A, acompanhado de um maior FMA; no nível T, apenas Co-Gn e ENA-Me foram maiores no grupo de Classe II do gênero masculino. Na comparação entre os gêneros do grupo de Oclusão Normal no nível I, as medidas de FMA e NS.Gn foram maiores no gênero masculino, que também apresentaram significância estatística no nível A, acompanhados do Co-A, SNB, PNPerp, Co-Gn e ENA-Me, enquanto o gênero feminino apresentou maior valor de NSBa; no nível T, apenas Co-Go foi estatisticamente maior no gênero masculino. Na comparação entre os grupos do gênero feminino e nível I, o grupo de Classe II apresentou significância estatística para as variáveis A-Nperp, Co-Go, ANB, SN.GoGn, NS.Gn, BaN.PtGn, ENA-Me e NSBA; na fase A, as medidas Co-Go, ANB, NS.Gn, ENA-Me e NSBa foram maiores no grupo de Classe II que apresentou menor BaN.PtGn; na fase T, apenas Co-Go e BaN.PtGn permaneceram significantes para o grupo de Classe II. Na comparação entre os grupos do gênero masculino e nível I, as variáveis SNB, Co-Gn, Co-Go, ANB, ENA-Me e NSBa foram maiores no grupo de Classe II; no nível A, apenas SNB, ANB e BaNPtGn foram significantes, e permaneceram também no nível T. Avaliando os grupos do gênero…
Advisors/Committee Members: Pinzan, Arnaldo.
Subjects/Keywords: Cervical vertebrae; Class II malocclusion; Classe II de Angle; Craniofacial growth; Crescimento craniofacial; Idade esquelética; Skeletal age; Vértebras cervicais
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Silva, F. L. B. S. (2010). Avaliação cefalométrica do crescimento craniofacial em crianças leucodermas brasileiras, com má oclusão de Classe II durante as fases de crescimento determinadas pela maturação das vértebras cervicais. (Doctoral Dissertation). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/25/25134/tde-18082010-102325/ ;
Chicago Manual of Style (16th Edition):
Silva, Fabiane Louly Baptista Santos. “Avaliação cefalométrica do crescimento craniofacial em crianças leucodermas brasileiras, com má oclusão de Classe II durante as fases de crescimento determinadas pela maturação das vértebras cervicais.” 2010. Doctoral Dissertation, University of São Paulo. Accessed March 05, 2021.
http://www.teses.usp.br/teses/disponiveis/25/25134/tde-18082010-102325/ ;.
MLA Handbook (7th Edition):
Silva, Fabiane Louly Baptista Santos. “Avaliação cefalométrica do crescimento craniofacial em crianças leucodermas brasileiras, com má oclusão de Classe II durante as fases de crescimento determinadas pela maturação das vértebras cervicais.” 2010. Web. 05 Mar 2021.
Vancouver:
Silva FLBS. Avaliação cefalométrica do crescimento craniofacial em crianças leucodermas brasileiras, com má oclusão de Classe II durante as fases de crescimento determinadas pela maturação das vértebras cervicais. [Internet] [Doctoral dissertation]. University of São Paulo; 2010. [cited 2021 Mar 05].
Available from: http://www.teses.usp.br/teses/disponiveis/25/25134/tde-18082010-102325/ ;.
Council of Science Editors:
Silva FLBS. Avaliação cefalométrica do crescimento craniofacial em crianças leucodermas brasileiras, com má oclusão de Classe II durante as fases de crescimento determinadas pela maturação das vértebras cervicais. [Doctoral Dissertation]. University of São Paulo; 2010. Available from: http://www.teses.usp.br/teses/disponiveis/25/25134/tde-18082010-102325/ ;
29.
OLIVEIRA, Carmen Daniella Batista de.
Alterações da comunicação em vítimas de acidente de transporte terrestre atendidas pelo SAMU Recife
.
Degree: 2016, Universidade Federal de Pernambuco
URL: https://repositorio.ufpe.br/handle/123456789/17643
► O objetivo do estudo foi identificar a prevalência e os fatores associados às alterações da comunicação nas vítimas de acidente de transporte terrestre, no momento…
(more)
▼ O objetivo do estudo foi identificar a prevalência e os fatores associados às alterações da comunicação nas vítimas de acidente de transporte terrestre, no momento do atendimento pré-hospitalar no município do Recife. Trata-se de um estudo seccional, onde foram analisados os prontuários das vítimas de acidentes de transporte terrestre atendidas pelo SAMU-Recife, entre junho/2013 e julho/2014. Foram calculadas as prevalências das variáveis dependentes. O Teste Qui-Quadrado e o Teste Exato de Fisher selecionaram as variáveis associadas ao desfecho, considerado significante p < 0,05. Para a seleção das variáveis para a análise multivariada, foi considerada significância ≤ 0,20. Como resultados, foram elaborados dois artigos: uma revisão sistemática como parte da fundamentação teórica e um artigo original que estudou 4.298 vítimas, a maioria homens (75,3%) entre 20 a 29 anos (58%). Foram identificadas as prevalências para ausência de resposta verbal e dificuldade de fala de 4,11% e 3,14%, respectivamente. Observadas associação de ausência de resposta verbal e dificuldade de fala em motociclistas e ciclistas, que não usavam capacete, com agitação psicomotora, lesões de face, dispneia, obstrução de vias aéreas e que ingeriram bebida alcóolica. A medida da prevalência das alterações da comunicação em vítimas de acidente de transporte terrestre e os fatores associados encontrados foram considerados relevantes por ser, até então, desconhecidos pela comunidade científica, sendo necessário que os serviços de atendimento pré-hospitalar, hospitalar e de reabilitação estejam preparados para avaliar e atender essas vítimas.
Advisors/Committee Members: LIMA, Maria Luiza Lopes Timóteo de (advisor), SILVA,Vanessa de Lima (advisor), https://repositorio.ufpe.br/handle/123456789/17643 (advisor).
Subjects/Keywords: Acidente de trânsito. Trauma. Transtornos da comunicação. Craniofacial. Face.;
Accident traffic. Trauma. Communication disorders. Craniofacial. Face
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
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Manager
APA (6th Edition):
OLIVEIRA, C. D. B. d. (2016). Alterações da comunicação em vítimas de acidente de transporte terrestre atendidas pelo SAMU Recife
. (Masters Thesis). Universidade Federal de Pernambuco. Retrieved from https://repositorio.ufpe.br/handle/123456789/17643
Chicago Manual of Style (16th Edition):
OLIVEIRA, Carmen Daniella Batista de. “Alterações da comunicação em vítimas de acidente de transporte terrestre atendidas pelo SAMU Recife
.” 2016. Masters Thesis, Universidade Federal de Pernambuco. Accessed March 05, 2021.
https://repositorio.ufpe.br/handle/123456789/17643.
MLA Handbook (7th Edition):
OLIVEIRA, Carmen Daniella Batista de. “Alterações da comunicação em vítimas de acidente de transporte terrestre atendidas pelo SAMU Recife
.” 2016. Web. 05 Mar 2021.
Vancouver:
OLIVEIRA CDBd. Alterações da comunicação em vítimas de acidente de transporte terrestre atendidas pelo SAMU Recife
. [Internet] [Masters thesis]. Universidade Federal de Pernambuco; 2016. [cited 2021 Mar 05].
Available from: https://repositorio.ufpe.br/handle/123456789/17643.
Council of Science Editors:
OLIVEIRA CDBd. Alterações da comunicação em vítimas de acidente de transporte terrestre atendidas pelo SAMU Recife
. [Masters Thesis]. Universidade Federal de Pernambuco; 2016. Available from: https://repositorio.ufpe.br/handle/123456789/17643

University of California – San Francisco
30.
Yu, Jane.
On Generation of Variation in Craniofacial Development and Evolution.
Degree: Biomedical Sciences, 2012, University of California – San Francisco
URL: http://www.escholarship.org/uc/item/4b41w2rx
► Avian species display a remarkable diversity of facial morphologies, from the small, pointed, insect-catching beak of the common sparrow, to the long, narrow, nectar-sipping beak…
(more)
▼ Avian species display a remarkable diversity of facial morphologies, from the small, pointed, insect-catching beak of the common sparrow, to the long, narrow, nectar-sipping beak of a hummingbird. Using fate-mapping studies, we know that all facial skeletal elements are derived from neural crest mesenchyme (NCM), a multipotent embryonic cell population. From transplant experiments, we know that NCM plays an instructive role in patterning and growth in the face (i.e., when we transplant quail NCM into a duck host, the chimera forms a quail-like face and beak). What remains to be understood is how NCM carries out the components of what is undoubtedly a very complex task - to pattern beaks with great precision for function in established niches, but also to allow plasticity for evolution in response to changes in the natural environment.Thus, one of the questions I address during my dissertation research is what are developmental, cellular, and molecular mechanisms underlying evolvability in avian faces? I have previously been intrigued by the rapid rate of generation of novel beak morphologies as historically described in Darwin's finches and other models. To begin to understand these phenomena, I investigated the function, regulation, and evolution of one transcription factor, Runx2, as a model for understanding processes that can modulate the generation of heritable, selectable, phenotypic variation.Runx2 is often considered a master regulator of osteogenesis. However, mechanisms by which Runx2 might regulate timing of osteogenesis in vivo have not been previously described. Here, by using a unique avian chimeric experimental system, we identify Runx2 as a critical player in both NCM-dependent timing of osteogenesis and developmental growth and patterning of the craniofacial complex. Specifically, we find that NCM controls stage- and species-specific cell cycle progression and Runx2 expression in highly interwoven processes. Further, Runx2 expression levels affect mandible size and correlate to species-specific sequence variation at a highly evolvable Runx2 regulatory region. Taken together, these data suggest that NCM may be able generate a range of skeletal element sizes and morphologies in part by temporally regulating cell cycle in conjunction with cell differentiation through highly regulated, mutation-labile transcription factors such as Runx2.
Subjects/Keywords: Evolution & development; Developmental biology; Morphology; Craniofacial Birth Defects; Craniofacial Development; Embryology; Evolvability; Morphological Variation; Neural Crest
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Manager
APA (6th Edition):
Yu, J. (2012). On Generation of Variation in Craniofacial Development and Evolution. (Thesis). University of California – San Francisco. Retrieved from http://www.escholarship.org/uc/item/4b41w2rx
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Yu, Jane. “On Generation of Variation in Craniofacial Development and Evolution.” 2012. Thesis, University of California – San Francisco. Accessed March 05, 2021.
http://www.escholarship.org/uc/item/4b41w2rx.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Yu, Jane. “On Generation of Variation in Craniofacial Development and Evolution.” 2012. Web. 05 Mar 2021.
Vancouver:
Yu J. On Generation of Variation in Craniofacial Development and Evolution. [Internet] [Thesis]. University of California – San Francisco; 2012. [cited 2021 Mar 05].
Available from: http://www.escholarship.org/uc/item/4b41w2rx.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Yu J. On Generation of Variation in Craniofacial Development and Evolution. [Thesis]. University of California – San Francisco; 2012. Available from: http://www.escholarship.org/uc/item/4b41w2rx
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
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