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University of Toronto

1. Lin, Hause. Neurophysiological Signals Parametrically Track Subjective Conflict during Intertemporal Choice.

Degree: 2016, University of Toronto

When choosing between equally desirable options, how is decision conflict represented in the brain? We measured neurophysiological signals that are believed to reflect decision processes in different brain regions as participants made intertemporal decisions. Participant-specific delayed rewards (e.g., $20.30 in 10 days)â generated based on each participant's hyperbolic discount functionâ were presented to parametrically vary the amount of decision conflict in different choice pairs. We found that conflict negativity and pupil dilation track varying degrees of conflict, suggesting the anterior cingulate and locus coeruleus/norepinephrine system are implicated in value comparison and conflict monitoring processes. We show that the neuroeconomic and psychophysiological approaches can be integrated to better understand the neural systems and processes underlying decision making.

M.A.

Advisors/Committee Members: Inzlicht, Michael, Hutcherson, Cendri A, Psychology.

Subjects/Keywords: anterior cingulate cortex; conflict negativity; corrugator activity; decision conflict; intertemporal choice; pupil dilation; 0621

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Lin, H. (2016). Neurophysiological Signals Parametrically Track Subjective Conflict during Intertemporal Choice. (Masters Thesis). University of Toronto. Retrieved from http://hdl.handle.net/1807/75172

Chicago Manual of Style (16th Edition):

Lin, Hause. “Neurophysiological Signals Parametrically Track Subjective Conflict during Intertemporal Choice.” 2016. Masters Thesis, University of Toronto. Accessed December 13, 2019. http://hdl.handle.net/1807/75172.

MLA Handbook (7th Edition):

Lin, Hause. “Neurophysiological Signals Parametrically Track Subjective Conflict during Intertemporal Choice.” 2016. Web. 13 Dec 2019.

Vancouver:

Lin H. Neurophysiological Signals Parametrically Track Subjective Conflict during Intertemporal Choice. [Internet] [Masters thesis]. University of Toronto; 2016. [cited 2019 Dec 13]. Available from: http://hdl.handle.net/1807/75172.

Council of Science Editors:

Lin H. Neurophysiological Signals Parametrically Track Subjective Conflict during Intertemporal Choice. [Masters Thesis]. University of Toronto; 2016. Available from: http://hdl.handle.net/1807/75172


Université du Luxembourg

2. Scheuren, Raymonde. ASSESSMENT OF PSYCHOLOGICAL AND PSYCHOPHYSIOLOGICAL CHARACTERISTICS INVOLVED IN THE MODULATION OF ENDOGENOUS PAIN CONTROL PATHWAYS AND IN THE INDUCTION OF PARADOXICAL PAIN.

Degree: 2014, Université du Luxembourg

The present doctoral thesis involves three experimental studies on pain processing and its modulation by psychological mechanisms. The first investigation focused on the relationship between associative learning aspects and the endogenous pain control system referred to as diffuse noxious inhibitory controls (DNIC) or conditioned pain modulation (CPM). The aim of the study consisted in uncovering whether descending pain inhibition may depend on specific environmental or circumstantial cues that have been linked to a reduction of pain sensations through associative learning in pain treatment contexts. A heterotopic noxious counter-stimulation (HNCS) was used to trigger the endogenous pain control system in the experimental context. For the study of the potential impact of associative learning on the pain-inhibits-pain phenomenon, a respondent (Pavlovian) conditioning procedure was realized during the HNCS stimulation. It could be shown that the repeated pairing of a phone signal (conditioned stimulus, CS) with the unconditioned tonic pain stimulus (UCS, HNCS) enabled the CS in the post-conditioning phase to generate a DNIC-like effect similar to the one induced by the tonic pain stimulus. The results demonstrated that learning processes are able to influence endogenous pain modulation processes and decreases in pain perceptions and reflex activity. A thermal grill paradigm was used in the second and third study to examine the influence of psychological characteristics on the individual disposition to display the thermal grill illusion (TGI) of pain. First, the impact of pain-related personality traits like trait anxiety, pain catastrophizing, rumination, pessimism, expectancy of pain, suggestibility and interoceptive accuracy on inter-individual differences in paradoxical pain sensitivity was assessed. Second, the potential influence of dispositional self-regulation ability on illusive pain perceptions was measured. Vagally mediated heart rate variability (HRV) at rest was used as an index of individual self-regulatory strength. The results allowed identifying several psychological factors that are substantially affecting thermal grill-related perceptions. Mainly ruminative and interoceptive accuracy features increased the probability of paradoxical pain perceptions. The likelihood of the TGI elicitation was in addition significantly affected by the magnitude of the HRV-indicator respiratory sinus arrhythmia (RSA). Since thermal grill and neuropathic pain-related pain processing share common neural pathways, the identified psychological effects may be relevant in the context of pathological pain conditions. Advisors/Committee Members: National research council of Luxembourg (Fonds National de la Recherche) [sponsor], Anton, Fernand [superviser], Ferring, Dieter [president of the jury], Magerl, Walter [member of the jury], Schächinger, Hartmut [member of the jury], Van Damme, Stefan [member of the jury].

Subjects/Keywords: Diffuse noxious inhibitory controls; Respondent conditioning; RIII flexion reflex; Thermal grill illusion; Paradoxical pain; Rumination; Interoceptive accuracy; Vagally mediated heart rate variability; Self-regulation; Responder; Corrugator muscle activity; Endogenous pain control mechanism; Social & behavioral sciences, psychology :: Animal psychology, ethology & psychobiology [H01]; Sciences sociales & comportementales, psychologie :: Psychologie animale, éthologie & psychobiologie [H01]

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Scheuren, R. (2014). ASSESSMENT OF PSYCHOLOGICAL AND PSYCHOPHYSIOLOGICAL CHARACTERISTICS INVOLVED IN THE MODULATION OF ENDOGENOUS PAIN CONTROL PATHWAYS AND IN THE INDUCTION OF PARADOXICAL PAIN. (Doctoral Dissertation). Université du Luxembourg. Retrieved from http://orbilu.uni.lu/handle/10993/18666

Chicago Manual of Style (16th Edition):

Scheuren, Raymonde. “ASSESSMENT OF PSYCHOLOGICAL AND PSYCHOPHYSIOLOGICAL CHARACTERISTICS INVOLVED IN THE MODULATION OF ENDOGENOUS PAIN CONTROL PATHWAYS AND IN THE INDUCTION OF PARADOXICAL PAIN.” 2014. Doctoral Dissertation, Université du Luxembourg. Accessed December 13, 2019. http://orbilu.uni.lu/handle/10993/18666.

MLA Handbook (7th Edition):

Scheuren, Raymonde. “ASSESSMENT OF PSYCHOLOGICAL AND PSYCHOPHYSIOLOGICAL CHARACTERISTICS INVOLVED IN THE MODULATION OF ENDOGENOUS PAIN CONTROL PATHWAYS AND IN THE INDUCTION OF PARADOXICAL PAIN.” 2014. Web. 13 Dec 2019.

Vancouver:

Scheuren R. ASSESSMENT OF PSYCHOLOGICAL AND PSYCHOPHYSIOLOGICAL CHARACTERISTICS INVOLVED IN THE MODULATION OF ENDOGENOUS PAIN CONTROL PATHWAYS AND IN THE INDUCTION OF PARADOXICAL PAIN. [Internet] [Doctoral dissertation]. Université du Luxembourg; 2014. [cited 2019 Dec 13]. Available from: http://orbilu.uni.lu/handle/10993/18666.

Council of Science Editors:

Scheuren R. ASSESSMENT OF PSYCHOLOGICAL AND PSYCHOPHYSIOLOGICAL CHARACTERISTICS INVOLVED IN THE MODULATION OF ENDOGENOUS PAIN CONTROL PATHWAYS AND IN THE INDUCTION OF PARADOXICAL PAIN. [Doctoral Dissertation]. Université du Luxembourg; 2014. Available from: http://orbilu.uni.lu/handle/10993/18666

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