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1.
Dantas, Paulo Elias Corrêa.
Alterações topográficas da córnea em pacientes com cérato-conjuntivite vernal.
Degree: PhD, Oftalmologia, 2002, University of São Paulo
URL: http://www.teses.usp.br/teses/disponiveis/5/5149/tde-07032002-002915/
;
► Doença alérgica ocular acomete cerca de ¼ da população mundial. Dentro do espectro da doença alérgica ocular, a cérato-conjuntivite vernal, que afeta principalmente crianças, pode…
(more)
▼ Doença alérgica ocular acomete cerca de ¼ da população mundial. Dentro do espectro da doença alérgica ocular, a cérato-conjuntivite vernal, que afeta principalmente crianças, pode apresentar-se sob forma severa e persistente, levando a dano do tecido corneal e comprometimento da função visual. Traumatismo epitelial crônico, induzido pelo ato de coçar os olhos, associado ao intenso prurido ocular tem sido apontado como fator de risco importante na patogênese do ceratocone. Pode estimular a apoptose prematura dos ceratócitos, provocando mudanças estruturais do estroma da córnea. A associação de cérato-conjuntivite vernal e ceratocone tem sido apontada como freqüente na literatura oftalmológica através de estudos descritivos e qualitativos, que, entretanto, não auxiliam na detecção precoce da doença ectásica corneal, prejudicando sua análise epidemiológica, seu estudo genético e a definição de sua patogênese. Propôs-se estudo clínico caso-controle de pacientes com cérato-conjuntivite vernal do Ambulatório de Alergia Ocular do Departamento de Oftalmologia da Santa Casa de São Paulo, com finalidade de obter-se, por meio da análise topográfica computadorizada de córnea utilizando-se de descritor quantitativo da superfície anterior da córnea (sumário diagnóstico de Holladay), informações sobre as alterações topográficas da superfície anterior da córnea, que pudessem determinar a freqüência da associação entre cérato-conjuntivite vernal e ceratocone, além de seus efeitos sobre o desempenho da visão destes pacientes. Os resultados obtidos neste estudo mostram alta freqüência de ceratocone em pacientes com cérato-conjuntivite vernal. A performance visual destes pacientes é influenciada pelas aberrações provocadas por alterações da asfericidade corneal e de outras variáveis topográficas.
Allergic ocular disease affects ¼ of the world population. Inside the spectrum of the allergic ocular disease, vernal keratoconjunctivitis, that affects mostly children, may present as severe and persistent form, leading to corneal tissue damage and disturbing visual function. Chronic epithelial trauma, provoked by eye rubbing due to intense ocular itching, has been postulated as an important risk factor in the pathogenesis of keratoconus. It may induce early keratocyte apoptosis that results in structural changes to the corneal stroma. The association of keratoconus with vernal keratoconjunctivitis has been observed to be frequent in the ophthalmological literature by descriptive and qualitative studies, unable to detect earlier forms of this ectatic corneal disease, weakening epidemiological analysis, genetic studies and the definition of its pathogenesis. We proposed a case-control clinical study of patients with vernal keratoconjunctivitis from the Ambulatory of Ocular Allergy of the Department of Ophthalmology of Santa Casa of São Paulo, aiming for information on the anterior corneal curvature and visual performance, using a quantitative descriptor analyzer (Holladay Diagnostic Summary). The results suggest high frequency of the…
Advisors/Committee Members: Alves, Milton Ruiz.
Subjects/Keywords: allergic conjunctivitis; ceratocone/diagnóstico; ceratocone/epidemiologia; conjuntivite alérgica/diagnóstico; conjuntivite alérgica/epidemiologia; corneal disease; corneal topography; doenças da córnea/diagnóstico; doenças da córnea/epidemiologia; keratoconus; topografia da córnea/estatística e dados numéricos
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APA (6th Edition):
Dantas, P. E. C. (2002). Alterações topográficas da córnea em pacientes com cérato-conjuntivite vernal. (Doctoral Dissertation). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/5/5149/tde-07032002-002915/ ;
Chicago Manual of Style (16th Edition):
Dantas, Paulo Elias Corrêa. “Alterações topográficas da córnea em pacientes com cérato-conjuntivite vernal.” 2002. Doctoral Dissertation, University of São Paulo. Accessed March 09, 2021.
http://www.teses.usp.br/teses/disponiveis/5/5149/tde-07032002-002915/ ;.
MLA Handbook (7th Edition):
Dantas, Paulo Elias Corrêa. “Alterações topográficas da córnea em pacientes com cérato-conjuntivite vernal.” 2002. Web. 09 Mar 2021.
Vancouver:
Dantas PEC. Alterações topográficas da córnea em pacientes com cérato-conjuntivite vernal. [Internet] [Doctoral dissertation]. University of São Paulo; 2002. [cited 2021 Mar 09].
Available from: http://www.teses.usp.br/teses/disponiveis/5/5149/tde-07032002-002915/ ;.
Council of Science Editors:
Dantas PEC. Alterações topográficas da córnea em pacientes com cérato-conjuntivite vernal. [Doctoral Dissertation]. University of São Paulo; 2002. Available from: http://www.teses.usp.br/teses/disponiveis/5/5149/tde-07032002-002915/ ;

Anna University
2.
Prasanna Devi S.
A study on improving certain pre transplantation decision
issues related to kidney and corneal transplantation
programs;.
Degree: 2013, Anna University
URL: http://shodhganga.inflibnet.ac.in/handle/10603/13434
► Organ transplantation is the most preferred treatment modality for patients with end-stage organ disease. At present the supply of cadaver organs is so inadequate as…
(more)
▼ Organ transplantation is the most preferred
treatment modality for patients with end-stage organ disease. At
present the supply of cadaver organs is so inadequate as not to be
commensurate with need. In India, there are very few Organ
Procurement Organizations (OPO s) to supervise the activities of
organ donation and transplantation at a national level. Our country
seems to lack an active organ sharing network both at the state and
national level. The present study focuses on integrating
applications of systems and industrial engineering techniques to
increase the number of organ transplants in India, particularly at
the state level. i.e. in Tamil Nadu (Case study region). The
different issues considered for the study include: A retrospective
study of the renal failure patients was done to understand the
association of the lifestyle factors and the Chronic Kidney Disease
(CKD); A system dynamics simulation study was carried out to study
the various dynamics involved in organ transplants, in particular
corneal transplants.; A website has been designed, developed and
launched to promote organ donation awareness among the community,
which is most critical to increase the number of transplants in our
country; Networking of approved Transplant Centres (TC s) and
optimal location for setting up of OPO s were proposed using
facility location P-median model. This will facilitate optimal
distribution and allocation of deceased organs to recipients in the
waiting list without organ wastage due to lapse of the Cold
Ischemic Time (CIT); A simulation study was carried out on the
world renowned different transplantation programmes and compared
with the Cadaver Transplant Program (CTP) which is the only
legalized transplantation program in India. The evaluation has been
done to find out the waiting time of different blood group patients
and the best serving programme for a particular blood type patient
is thus recommended to minimize the waiting time of the patient.
newline
Appendices 1 to 7; pp.154-187
Advisors/Committee Members: Suryaprakasa Rao, K..
Subjects/Keywords: Pre-transplantation; kidney; corneal transplantation;
Chronic Kidney Disease (CKD); Tamil Nadu; Transplant Centres; Cold
Ischemic Time; Cold Ischemic Time; India
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
S, P. D. (2013). A study on improving certain pre transplantation decision
issues related to kidney and corneal transplantation
programs;. (Thesis). Anna University. Retrieved from http://shodhganga.inflibnet.ac.in/handle/10603/13434
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
S, Prasanna Devi. “A study on improving certain pre transplantation decision
issues related to kidney and corneal transplantation
programs;.” 2013. Thesis, Anna University. Accessed March 09, 2021.
http://shodhganga.inflibnet.ac.in/handle/10603/13434.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
S, Prasanna Devi. “A study on improving certain pre transplantation decision
issues related to kidney and corneal transplantation
programs;.” 2013. Web. 09 Mar 2021.
Vancouver:
S PD. A study on improving certain pre transplantation decision
issues related to kidney and corneal transplantation
programs;. [Internet] [Thesis]. Anna University; 2013. [cited 2021 Mar 09].
Available from: http://shodhganga.inflibnet.ac.in/handle/10603/13434.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
S PD. A study on improving certain pre transplantation decision
issues related to kidney and corneal transplantation
programs;. [Thesis]. Anna University; 2013. Available from: http://shodhganga.inflibnet.ac.in/handle/10603/13434
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
3.
Schweitzer, Cédric.
Analyse épidémiologique du glaucome dans une population âgée : l'étude ALIENOR (Antioxydants, Lipides Essentiels, Nutrition et maladies Occulaires) : Epidemiology ou glaucoma in an elderly population : the Alienor Study.
Degree: Docteur es, Santé publique. Option : Epidémiologie, 2016, Bordeaux
URL: http://www.theses.fr/2016BORD0186
► Le glaucome est une maladie neurodégénérative qui se définit par une perte progressive en fibres nerveuses rétiniennes et un rétrécissement du champ visuel. Il s’agit…
(more)
▼ Le glaucome est une maladie neurodégénérative qui se définit par une perte progressive en fibres nerveuses rétiniennes et un rétrécissement du champ visuel. Il s’agit de la première cause de cécité irréversible dans le monde et le principal facteur de risque est la pression intraoculaire (PIO). L’étude ALIENOR (Antioxydants, Lipides Essentiels, Nutrition et maladies OculaiRes) est une étude épidémiologique qui a pour but de déterminer l’incidence des différentes pathologies oculaires liées à l’âge avec les facteurs nutritionnels, démographiques ou environnementaux dans une population représentative de la région de Bordeaux. En 2009-2010, 624 sujets âgés de plus de 74 ans ont bénéficié d’un examen ophtalmologique complet incluant un examen du nerf optique en rétinophotographie et en tomographie à cohérence optique spectral-domain (SD-OCT), d’une mesure la PIO au tonomètre à air et d’une évaluation des propriétés biomécaniques de la cornée. Une mesure de l’accumulation cutanée de produits de glycation avancée a été réalisée par autofluorescence. Le diagnostic de glaucome a été réalisé en utilisant les critères de la classification ISGEO (International Society for Epidemiologic and Geographical Ophthalmology). Les paramètres biomécaniques de la cornée étaient modifiés avec l’âge et chez les sujets ayant une histoire résidentielle à des latitudes plus exposées aux ultraviolets ambiants. L’épaisseur de cornée était plus élevée chez les sujets anciennement fumeurs. L’autofluorescence cutanée ≥ 2.7 UA (Unité Arbitraire) était indépendamment associée au glaucome. Les paramètres d’épaisseur en fibres nerveuses rétiniennes du SD-OCT présentaient de bonnes performances diagnostiques pour discriminer les sujets glaucomateux des témoins et la base normative présentait de bonnes performances discriminatives lorsqu’au moins un des paramètres était considéré comme anormal. Notre étude apporte des résultats originaux en termes de facteurs de risque de glaucome ou de déterminants des facteurs de risque de glaucome. De plus les performances diagnostiques du SD-OCT pourraient fournir des informations utiles pour optimiser les stratégies de dépistage du glaucome dans une population générale âgée.
Glaucoma is a neurodegenerative disease defined by a progressive loss of optic nerve axons and retinal ganglion cells resulting in a characteristic enlargement of the optic nerve head cup and associated visual field defects. It remains the first cause of irreversible blindness worldwide and intraocular pressure (IOP) is the main risk factor. The ALIENOR (Antioxydants, Lipides Essentiels, Nutrition et maladies OculaiRes) study is a population-based study. It aims to assess the associations of age-related eye diseases with nutritional, demographic and environmental factors in a representative population of the Bordeaux area. In 2009-2010, 624 subjects, aged 74 years or more, underwent a complete eye examination, including an optic nerve head evaluation using retinophotography and a spectral-domain optical coherence tomography (SD-OCT), an IOP…
Advisors/Committee Members: Delcourt, Cécile (thesis director).
Subjects/Keywords: Epidémiologie; Glaucome; Vieillissement oculaire; Dépistage glaucome; Biomécanique cornéenne; Produits de glycation avancée; Epidemiology; Glaucoma; Age-related eye disease; Glaucoma screening; Corneal biomechanics; Advanced glycation end-products
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Schweitzer, C. (2016). Analyse épidémiologique du glaucome dans une population âgée : l'étude ALIENOR (Antioxydants, Lipides Essentiels, Nutrition et maladies Occulaires) : Epidemiology ou glaucoma in an elderly population : the Alienor Study. (Doctoral Dissertation). Bordeaux. Retrieved from http://www.theses.fr/2016BORD0186
Chicago Manual of Style (16th Edition):
Schweitzer, Cédric. “Analyse épidémiologique du glaucome dans une population âgée : l'étude ALIENOR (Antioxydants, Lipides Essentiels, Nutrition et maladies Occulaires) : Epidemiology ou glaucoma in an elderly population : the Alienor Study.” 2016. Doctoral Dissertation, Bordeaux. Accessed March 09, 2021.
http://www.theses.fr/2016BORD0186.
MLA Handbook (7th Edition):
Schweitzer, Cédric. “Analyse épidémiologique du glaucome dans une population âgée : l'étude ALIENOR (Antioxydants, Lipides Essentiels, Nutrition et maladies Occulaires) : Epidemiology ou glaucoma in an elderly population : the Alienor Study.” 2016. Web. 09 Mar 2021.
Vancouver:
Schweitzer C. Analyse épidémiologique du glaucome dans une population âgée : l'étude ALIENOR (Antioxydants, Lipides Essentiels, Nutrition et maladies Occulaires) : Epidemiology ou glaucoma in an elderly population : the Alienor Study. [Internet] [Doctoral dissertation]. Bordeaux; 2016. [cited 2021 Mar 09].
Available from: http://www.theses.fr/2016BORD0186.
Council of Science Editors:
Schweitzer C. Analyse épidémiologique du glaucome dans une population âgée : l'étude ALIENOR (Antioxydants, Lipides Essentiels, Nutrition et maladies Occulaires) : Epidemiology ou glaucoma in an elderly population : the Alienor Study. [Doctoral Dissertation]. Bordeaux; 2016. Available from: http://www.theses.fr/2016BORD0186

Universitat Autònoma de Barcelona
4.
Segarra López, Sergi.
Estudios de escalada de dosis sobre los efectos del cloruro de benzalconio intracameral en conejos: un modelo animal de enfermedad endotelial corneal.
Degree: Departament de Medicina i Cirurgia Animals, 2016, Universitat Autònoma de Barcelona
URL: http://hdl.handle.net/10803/393871
► Objective: Find a dose of benzalkonium chloride (BAC) which, injected into the anterior chamber in rabbits, causes a selective damage on the corneal endothelium, without…
(more)
▼ Objective: Find a dose of benzalkonium chloride (BAC) which, injected into the anterior chamber in rabbits, causes a selective damage on the
corneal endothelium, without affecting the rest of intraocular structures and thus can be used to induce a repeatable and reproducible animal model of
corneal endothelial
disease.
Material and Methods: First, an ex vivo study was performed using 40 rabbit eyes obtained postmortem, which were classified into 8 groups depending on the injected compound: Control (no injection), Balance salt solution (BSS), and increasing concentrations of BAC (0.005%, 0.01%, 0.025%, 0.05%, 0.1% and 0.2%). Secondly, an in vivo study was performed using 24 New Zealand White rabbits, which were classified into 4 groups: BSS (control group); and 0.025%, 0.05% and 0.1% BAC. Only healthy rabbits and eyes without abnormalities were used. The intracameral injections were made at the corneoscleral limbus using a 27G needle and magnifying loupes. In both studies, follow-up assessments of ophthalmological examination, pachymetry and specular microscopy were performed (at 0, 6, 24 and 48 hours in the ex vivo study; and at 0, 2, 7 and 14 days in the in vivo study). Fourteen days after injection, the rabbits from the in vivo study were euthanized. At the end of each study, corneas were vital-stained and evaluated under the light microscope in order to assess the morphology and viability of the
corneal endothelial cells (CECs). In the in vivo study, histopathology of the eye globes was also performed.
Results: Ex vivo study: Compared to BSS, the CECs density began to decrease significantly with 0.025% BAC, while the CECs area, the degree of
corneal edema and the
corneal thickness increased significantly with 0.05%, 0.005% and 0.1% BAC, respectively. BAC concentrations of 0.05% and above caused significant increases in CECs mortality and pleomorphism, compared to control and BSS. In vivo study: Compared to BSS, concentrations of 0.025% BAC and above caused a significant increase in the degree of
corneal edema and
corneal thickness, and in CECs area and polymeghetism. CECs mortality was significantly higher with 0.05% BAC and above concentrations. The CECs density and hexagonality decreased significantly in all BAC groups. A concentration of 0.1% BAC resulted in a higher number of cases presenting with conjunctival congestion and
corneal ulcers. Histopathology revealed no significant alterations affecting the rest of the ocular structures after BAC injection.
Conclusions: Intracameral injection of 0.1 ml 0.05% BAC in rabbits causes a selective damage on the
corneal endothelium, without affecting the rest of intraocular structures. This technique, developed and validated in an ex vivo and an in vivo study, could be used to induce a repeatable and reproducible animal model of endothelial
corneal disease in rabbits.
Advisors/Committee Members: [email protected] (authoremail), true (authoremailshow), Leiva Repiso, Marta (director), Peña Giménez, Mª Teresa (director), Leiva Repiso, Marta (tutor), true (authorsendemail).
Subjects/Keywords: Model animal; Modelo animal; Animal model; Clorur de benzalconio; Cloruro de benzalconio; Benzalkonium chloride; Malaltia endotelial corneal; Enfermedad endotelial cornela; Corneal endothelial disease; Ciències de la Salut; 617
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Segarra López, S. (2016). Estudios de escalada de dosis sobre los efectos del cloruro de benzalconio intracameral en conejos: un modelo animal de enfermedad endotelial corneal. (Thesis). Universitat Autònoma de Barcelona. Retrieved from http://hdl.handle.net/10803/393871
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Segarra López, Sergi. “Estudios de escalada de dosis sobre los efectos del cloruro de benzalconio intracameral en conejos: un modelo animal de enfermedad endotelial corneal.” 2016. Thesis, Universitat Autònoma de Barcelona. Accessed March 09, 2021.
http://hdl.handle.net/10803/393871.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Segarra López, Sergi. “Estudios de escalada de dosis sobre los efectos del cloruro de benzalconio intracameral en conejos: un modelo animal de enfermedad endotelial corneal.” 2016. Web. 09 Mar 2021.
Vancouver:
Segarra López S. Estudios de escalada de dosis sobre los efectos del cloruro de benzalconio intracameral en conejos: un modelo animal de enfermedad endotelial corneal. [Internet] [Thesis]. Universitat Autònoma de Barcelona; 2016. [cited 2021 Mar 09].
Available from: http://hdl.handle.net/10803/393871.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Segarra López S. Estudios de escalada de dosis sobre los efectos del cloruro de benzalconio intracameral en conejos: un modelo animal de enfermedad endotelial corneal. [Thesis]. Universitat Autònoma de Barcelona; 2016. Available from: http://hdl.handle.net/10803/393871
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of New South Wales
5.
Tummanapalli, Shyam Sunder.
Evaluation of corneal nerves and tear neuropeptides in diabetic peripheral neuropathy.
Degree: Optometry & Vision Science, 2020, University of New South Wales
URL: http://handle.unsw.edu.au/1959.4/65060
;
https://unsworks.unsw.edu.au/fapi/datastream/unsworks:63698/SOURCE02?view=true
► Background: Corneal nerve fibers express diffusible, trophic neuropeptides such as substance P and calcitonin gene-related peptide (CGRP) into tears in response to neurogenic inflammation. Impaired…
(more)
▼ Background:
Corneal nerve fibers express diffusible, trophic neuropeptides such as substance P and calcitonin gene-related peptide (CGRP) into tears in response to neurogenic inflammation. Impaired
corneal nerve fibers have been proposed as early indicators of diabetic peripheral neuropathy (DPN). However, the changes that occur in the concentration of these neuropeptides and their relationship with peripheral neuropathy in the diabetic cohort has not been explored.Aim: To demonstrate the changes the concentrations of substance P and CGRP in tears as a result of
corneal denervation in diabetes and their association with severity of DPN. Methods: The concentrations of substance P and CGRP in flush tears were measured by enzyme-linked immunosorbent assay.
Corneal nerve fibers were assessed using
corneal confocal microscopy. Motor nerve axonal excitability tests were conducted to assess axonal function.Results: Age was identified as a confounding factor and controlled in all subsequent studies.
Corneal nerve fiber loss was associated with early markers of axonal dysfunction and severity of neuropathy in type 1 diabetes, suggesting that
corneal nerve loss is a generalized neuropathic process. There was a significant reduction in the concentration of substance P in tears in people with type 1 diabetic neuropathy. The concentration of substance P in tears was associated with
corneal nerve loss and with the severity of peripheral neuropathy in type 1 diabetes. In type 2 diabetes, there was no difference in neuropeptides between groups, regardless of neuropathic status. In both type 1 and type 2 diabetes,
corneal nerve parameters were significantly decreased in DPN.
Corneal confocal microscopy had a better diagnostic performance than the nerve excitability measures for detecting DPN in a cohort of participants with type 1 and type 2 diabetes. Tear film substance P concentration had a relatively good diagnostic efficiency in the assessment of DPN and may be used as a potential proxy marker for peripheral neuropathy in type 1 diabetes, but not in type 2 diabetes. The co-existence of renal dysfunction with diabetes does have an added detrimental effect on
corneal small nerve fibers.Conclusion: The ocular surface can indeed be a useful means to detect peripheral neuropathic status in diabetes. The measurement of tear film substance P offers significant promise in the detection of DPN.
Advisors/Committee Members: Markoulli, Maria, Optometry & Vision Science, Faculty of Science, UNSW, Willcox, Mark, Optometry & Vision Science, Faculty of Science, UNSW, Poynten, Ann, Department of Endocrinology, Prince of Wales Hospital, Sydney.
Subjects/Keywords: Tear neuropeptide; Diabetic peripheral neuropathy; Corneal confocal microscopy; Total neuropathy score; Type 2 diabetes; Tear film; Corneal nerves; Nerve excitability studies; Substance P; Calcitonin gene-related peptide; Chronic kidney disease; Flush tears; Inferior whorl; Fractal dimension; Type 1 diabetes
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Tummanapalli, S. S. (2020). Evaluation of corneal nerves and tear neuropeptides in diabetic peripheral neuropathy. (Doctoral Dissertation). University of New South Wales. Retrieved from http://handle.unsw.edu.au/1959.4/65060 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:63698/SOURCE02?view=true
Chicago Manual of Style (16th Edition):
Tummanapalli, Shyam Sunder. “Evaluation of corneal nerves and tear neuropeptides in diabetic peripheral neuropathy.” 2020. Doctoral Dissertation, University of New South Wales. Accessed March 09, 2021.
http://handle.unsw.edu.au/1959.4/65060 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:63698/SOURCE02?view=true.
MLA Handbook (7th Edition):
Tummanapalli, Shyam Sunder. “Evaluation of corneal nerves and tear neuropeptides in diabetic peripheral neuropathy.” 2020. Web. 09 Mar 2021.
Vancouver:
Tummanapalli SS. Evaluation of corneal nerves and tear neuropeptides in diabetic peripheral neuropathy. [Internet] [Doctoral dissertation]. University of New South Wales; 2020. [cited 2021 Mar 09].
Available from: http://handle.unsw.edu.au/1959.4/65060 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:63698/SOURCE02?view=true.
Council of Science Editors:
Tummanapalli SS. Evaluation of corneal nerves and tear neuropeptides in diabetic peripheral neuropathy. [Doctoral Dissertation]. University of New South Wales; 2020. Available from: http://handle.unsw.edu.au/1959.4/65060 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:63698/SOURCE02?view=true

Universiteit Utrecht
6.
Visser, E.S.
Objective and subjective performance of scleral lenses and new advances in scleral lens technologies.
Degree: 2015, Universiteit Utrecht
URL: http://dspace.library.uu.nl:8080/handle/1874/322813
► Scleral lenses are widely recognized for their ability to markedly improve quality of life and giving back patients their ability to perform daily activities, mainly…
(more)
▼ Scleral lenses are widely recognized for their ability to markedly improve quality of life and giving back patients their ability to perform daily activities, mainly as a result of restoring visual function and/or reduction of ocular discomfort and pain.Scleral lenses are an important front-line tool for managing many
corneal disorders refractory to other treatment measures and that otherwise would require keratoplasty. These disorders include conditions in which the cornea requires suitable optical correction in irregular surface, as well as to relieve symptoms, provide mechanical correction and/or facilitate
corneal healing in ocular surface
disease.
The fundaments for the research projects in this thesis started with the development of two key innovations (back-surface toric and tangential design) in scleral lenses by our team. These innovations are important steps towards maximizing patient comfort and optimizing scleral lens performance. The clinical and patient-oriented benefits of these internationally renowned breakthroughs are discussed in this thesis.
This thesis starts with a general introduction of the fundamental properties, complications, and indications of scleral lenses. Subsequently the role of scleral lenses in the context of other contact lens types is examined and made accessible for practitioners, by supplying a lens selection algorithm. Furthermore the focus of the research is on the indications and performance of modern scleral lenses, including the recent advances in scleral lens technologies (i.e., back-surface toric and tangential scleral lenses). Lastly, the use of scleral lenses following a relatively new treatment option for keratoconus (
corneal crosslinking, or CXL) is evaluated, and the effect of scleral lens use on
corneal physiology is examined.
Advisors/Committee Members: Imhof, S.M., Lelij, A. van der.
Subjects/Keywords: scleral lens; keratoconus; keratoplasty; dry eye disease; corneal crosslinking
Record Details
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Record Details
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Visser, E. S. (2015). Objective and subjective performance of scleral lenses and new advances in scleral lens technologies. (Doctoral Dissertation). Universiteit Utrecht. Retrieved from http://dspace.library.uu.nl:8080/handle/1874/322813
Chicago Manual of Style (16th Edition):
Visser, E S. “Objective and subjective performance of scleral lenses and new advances in scleral lens technologies.” 2015. Doctoral Dissertation, Universiteit Utrecht. Accessed March 09, 2021.
http://dspace.library.uu.nl:8080/handle/1874/322813.
MLA Handbook (7th Edition):
Visser, E S. “Objective and subjective performance of scleral lenses and new advances in scleral lens technologies.” 2015. Web. 09 Mar 2021.
Vancouver:
Visser ES. Objective and subjective performance of scleral lenses and new advances in scleral lens technologies. [Internet] [Doctoral dissertation]. Universiteit Utrecht; 2015. [cited 2021 Mar 09].
Available from: http://dspace.library.uu.nl:8080/handle/1874/322813.
Council of Science Editors:
Visser ES. Objective and subjective performance of scleral lenses and new advances in scleral lens technologies. [Doctoral Dissertation]. Universiteit Utrecht; 2015. Available from: http://dspace.library.uu.nl:8080/handle/1874/322813
7.
Visser, E.S.
Objective and subjective performance of scleral lenses and new advances in scleral lens technologies.
Degree: 2015, University Utrecht
URL: http://dspace.library.uu.nl/handle/1874/322813
;
URN:NBN:NL:UI:10-1874-322813
;
urn:isbn:978-90-393-6425-3
;
URN:NBN:NL:UI:10-1874-322813
;
http://dspace.library.uu.nl/handle/1874/322813
► Scleral lenses are widely recognized for their ability to markedly improve quality of life and giving back patients their ability to perform daily activities, mainly…
(more)
▼ Scleral lenses are widely recognized for their ability to markedly improve quality of life and giving back patients their ability to perform daily activities, mainly as a result of restoring visual function and/or reduction of ocular discomfort and pain.Scleral lenses are an important front-line tool for managing many
corneal disorders refractory to other treatment measures and that otherwise would require keratoplasty. These disorders include conditions in which the cornea requires suitable optical correction in irregular surface, as well as to relieve symptoms, provide mechanical correction and/or facilitate
corneal healing in ocular surface
disease.
The fundaments for the research projects in this thesis started with the development of two key innovations (back-surface toric and tangential design) in scleral lenses by our team. These innovations are important steps towards maximizing patient comfort and optimizing scleral lens performance. The clinical and patient-oriented benefits of these internationally renowned breakthroughs are discussed in this thesis.
This thesis starts with a general introduction of the fundamental properties, complications, and indications of scleral lenses. Subsequently the role of scleral lenses in the context of other contact lens types is examined and made accessible for practitioners, by supplying a lens selection algorithm. Furthermore the focus of the research is on the indications and performance of modern scleral lenses, including the recent advances in scleral lens technologies (i.e., back-surface toric and tangential scleral lenses). Lastly, the use of scleral lenses following a relatively new treatment option for keratoconus (
corneal crosslinking, or CXL) is evaluated, and the effect of scleral lens use on
corneal physiology is examined.
Advisors/Committee Members: Imhof, S.M., Lelij, A. van der.
Subjects/Keywords: scleral lens; keratoconus; keratoplasty; dry eye disease; corneal crosslinking
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share





❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Visser, E. S. (2015). Objective and subjective performance of scleral lenses and new advances in scleral lens technologies. (Doctoral Dissertation). University Utrecht. Retrieved from http://dspace.library.uu.nl/handle/1874/322813 ; URN:NBN:NL:UI:10-1874-322813 ; urn:isbn:978-90-393-6425-3 ; URN:NBN:NL:UI:10-1874-322813 ; http://dspace.library.uu.nl/handle/1874/322813
Chicago Manual of Style (16th Edition):
Visser, E S. “Objective and subjective performance of scleral lenses and new advances in scleral lens technologies.” 2015. Doctoral Dissertation, University Utrecht. Accessed March 09, 2021.
http://dspace.library.uu.nl/handle/1874/322813 ; URN:NBN:NL:UI:10-1874-322813 ; urn:isbn:978-90-393-6425-3 ; URN:NBN:NL:UI:10-1874-322813 ; http://dspace.library.uu.nl/handle/1874/322813.
MLA Handbook (7th Edition):
Visser, E S. “Objective and subjective performance of scleral lenses and new advances in scleral lens technologies.” 2015. Web. 09 Mar 2021.
Vancouver:
Visser ES. Objective and subjective performance of scleral lenses and new advances in scleral lens technologies. [Internet] [Doctoral dissertation]. University Utrecht; 2015. [cited 2021 Mar 09].
Available from: http://dspace.library.uu.nl/handle/1874/322813 ; URN:NBN:NL:UI:10-1874-322813 ; urn:isbn:978-90-393-6425-3 ; URN:NBN:NL:UI:10-1874-322813 ; http://dspace.library.uu.nl/handle/1874/322813.
Council of Science Editors:
Visser ES. Objective and subjective performance of scleral lenses and new advances in scleral lens technologies. [Doctoral Dissertation]. University Utrecht; 2015. Available from: http://dspace.library.uu.nl/handle/1874/322813 ; URN:NBN:NL:UI:10-1874-322813 ; urn:isbn:978-90-393-6425-3 ; URN:NBN:NL:UI:10-1874-322813 ; http://dspace.library.uu.nl/handle/1874/322813
8.
Visser, E.S.
Objective and subjective performance of scleral lenses and new advances in scleral lens technologies.
Degree: 2015, University Utrecht
URL: https://dspace.library.uu.nl/handle/1874/322813
;
URN:NBN:NL:UI:10-1874-322813
;
urn:isbn:978-90-393-6425-3
;
URN:NBN:NL:UI:10-1874-322813
;
https://dspace.library.uu.nl/handle/1874/322813
► Scleral lenses are widely recognized for their ability to markedly improve quality of life and giving back patients their ability to perform daily activities, mainly…
(more)
▼ Scleral lenses are widely recognized for their ability to markedly improve quality of life and giving back patients their ability to perform daily activities, mainly as a result of restoring visual function and/or reduction of ocular discomfort and pain.Scleral lenses are an important front-line tool for managing many
corneal disorders refractory to other treatment measures and that otherwise would require keratoplasty. These disorders include conditions in which the cornea requires suitable optical correction in irregular surface, as well as to relieve symptoms, provide mechanical correction and/or facilitate
corneal healing in ocular surface
disease.
The fundaments for the research projects in this thesis started with the development of two key innovations (back-surface toric and tangential design) in scleral lenses by our team. These innovations are important steps towards maximizing patient comfort and optimizing scleral lens performance. The clinical and patient-oriented benefits of these internationally renowned breakthroughs are discussed in this thesis.
This thesis starts with a general introduction of the fundamental properties, complications, and indications of scleral lenses. Subsequently the role of scleral lenses in the context of other contact lens types is examined and made accessible for practitioners, by supplying a lens selection algorithm. Furthermore the focus of the research is on the indications and performance of modern scleral lenses, including the recent advances in scleral lens technologies (i.e., back-surface toric and tangential scleral lenses). Lastly, the use of scleral lenses following a relatively new treatment option for keratoconus (
corneal crosslinking, or CXL) is evaluated, and the effect of scleral lens use on
corneal physiology is examined.
Advisors/Committee Members: Imhof, S.M., Lelij, A. van der.
Subjects/Keywords: scleral lens; keratoconus; keratoplasty; dry eye disease; corneal crosslinking
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share





❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Visser, E. S. (2015). Objective and subjective performance of scleral lenses and new advances in scleral lens technologies. (Doctoral Dissertation). University Utrecht. Retrieved from https://dspace.library.uu.nl/handle/1874/322813 ; URN:NBN:NL:UI:10-1874-322813 ; urn:isbn:978-90-393-6425-3 ; URN:NBN:NL:UI:10-1874-322813 ; https://dspace.library.uu.nl/handle/1874/322813
Chicago Manual of Style (16th Edition):
Visser, E S. “Objective and subjective performance of scleral lenses and new advances in scleral lens technologies.” 2015. Doctoral Dissertation, University Utrecht. Accessed March 09, 2021.
https://dspace.library.uu.nl/handle/1874/322813 ; URN:NBN:NL:UI:10-1874-322813 ; urn:isbn:978-90-393-6425-3 ; URN:NBN:NL:UI:10-1874-322813 ; https://dspace.library.uu.nl/handle/1874/322813.
MLA Handbook (7th Edition):
Visser, E S. “Objective and subjective performance of scleral lenses and new advances in scleral lens technologies.” 2015. Web. 09 Mar 2021.
Vancouver:
Visser ES. Objective and subjective performance of scleral lenses and new advances in scleral lens technologies. [Internet] [Doctoral dissertation]. University Utrecht; 2015. [cited 2021 Mar 09].
Available from: https://dspace.library.uu.nl/handle/1874/322813 ; URN:NBN:NL:UI:10-1874-322813 ; urn:isbn:978-90-393-6425-3 ; URN:NBN:NL:UI:10-1874-322813 ; https://dspace.library.uu.nl/handle/1874/322813.
Council of Science Editors:
Visser ES. Objective and subjective performance of scleral lenses and new advances in scleral lens technologies. [Doctoral Dissertation]. University Utrecht; 2015. Available from: https://dspace.library.uu.nl/handle/1874/322813 ; URN:NBN:NL:UI:10-1874-322813 ; urn:isbn:978-90-393-6425-3 ; URN:NBN:NL:UI:10-1874-322813 ; https://dspace.library.uu.nl/handle/1874/322813
.