subject:(conjuntivite al rgica epidemiologia)

1. Dantas, Paulo Elias Corrêa. Alterações topográficas da córnea em pacientes com cérato-conjuntivite vernal.

Degree: PhD, Oftalmologia, 2002, University of São Paulo

URL: http://www.teses.usp.br/teses/disponiveis/5/5149/tde-07032002-002915/ ;

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Doença alérgica ocular acomete cerca de ¼ da população mundial. Dentro do espectro da doença alérgica ocular, a cérato-conjuntivite vernal, que afeta principalmente crianças, pode… (more)

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Doença alérgica ocular acomete cerca de ¼ da população mundial. Dentro do espectro da doença alérgica ocular, a cérato-conjuntivite vernal, que afeta principalmente crianças, pode apresentar-se sob forma severa e persistente, levando a dano do tecido corneal e comprometimento da função visual. Traumatismo epitelial crônico, induzido pelo ato de coçar os olhos, associado ao intenso prurido ocular tem sido apontado como fator de risco importante na patogênese do ceratocone. Pode estimular a apoptose prematura dos ceratócitos, provocando mudanças estruturais do estroma da córnea. A associação de cérato-conjuntivite vernal e ceratocone tem sido apontada como freqüente na literatura oftalmológica através de estudos descritivos e qualitativos, que, entretanto, não auxiliam na detecção precoce da doença ectásica corneal, prejudicando sua análise epidemiológica, seu estudo genético e a definição de sua patogênese. Propôs-se estudo clínico caso-controle de pacientes com cérato-conjuntivite vernal do Ambulatório de Alergia Ocular do Departamento de Oftalmologia da Santa Casa de São Paulo, com finalidade de obter-se, por meio da análise topográfica computadorizada de córnea utilizando-se de descritor quantitativo da superfície anterior da córnea (sumário diagnóstico de Holladay), informações sobre as alterações topográficas da superfície anterior da córnea, que pudessem determinar a freqüência da associação entre cérato-conjuntivite vernal e ceratocone, além de seus efeitos sobre o desempenho da visão destes pacientes. Os resultados obtidos neste estudo mostram alta freqüência de ceratocone em pacientes com cérato-conjuntivite vernal. A performance visual destes pacientes é influenciada pelas aberrações provocadas por alterações da asfericidade corneal e de outras variáveis topográficas.

Allergic ocular disease affects ¼ of the world population. Inside the spectrum of the allergic ocular disease, vernal keratoconjunctivitis, that affects mostly children, may present as severe and persistent form, leading to corneal tissue damage and disturbing visual function. Chronic epithelial trauma, provoked by eye rubbing due to intense ocular itching, has been postulated as an important risk factor in the pathogenesis of keratoconus. It may induce early keratocyte apoptosis that results in structural changes to the corneal stroma. The association of keratoconus with vernal keratoconjunctivitis has been observed to be frequent in the ophthalmological literature by descriptive and qualitative studies, unable to detect earlier forms of this ectatic corneal disease, weakening epidemiological analysis, genetic studies and the definition of its pathogenesis. We proposed a case-control clinical study of patients with vernal keratoconjunctivitis from the Ambulatory of Ocular Allergy of the Department of Ophthalmology of Santa Casa of São Paulo, aiming for information on the anterior corneal curvature and visual performance, using a quantitative descriptor analyzer (Holladay Diagnostic Summary). The results suggest high frequency of the…

Advisors/Committee Members: Alves, Milton Ruiz.

Subjects/Keywords: allergic conjunctivitis; ceratocone/diagnóstico; ceratocone/epidemiologia; conjuntivite alérgica/diagnóstico; conjuntivite alérgica/epidemiologia; corneal disease; corneal topography; doenças da córnea/diagnóstico; doenças da córnea/epidemiologia; keratoconus; topografia da córnea/estatística e dados numéricos

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Dantas, P. E. C. (2002). Alterações topográficas da córnea em pacientes com cérato-conjuntivite vernal. (Doctoral Dissertation). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/5/5149/tde-07032002-002915/ ;

Chicago Manual of Style (16^th Edition):

Dantas, Paulo Elias Corrêa. “Alterações topográficas da córnea em pacientes com cérato-conjuntivite vernal.” 2002. Doctoral Dissertation, University of São Paulo. Accessed January 23, 2021. http://www.teses.usp.br/teses/disponiveis/5/5149/tde-07032002-002915/ ;.

MLA Handbook (7^th Edition):

Dantas, Paulo Elias Corrêa. “Alterações topográficas da córnea em pacientes com cérato-conjuntivite vernal.” 2002. Web. 23 Jan 2021.

Vancouver:

Dantas PEC. Alterações topográficas da córnea em pacientes com cérato-conjuntivite vernal. [Internet] [Doctoral dissertation]. University of São Paulo; 2002. [cited 2021 Jan 23]. Available from: http://www.teses.usp.br/teses/disponiveis/5/5149/tde-07032002-002915/ ;.

Council of Science Editors:

Dantas PEC. Alterações topográficas da córnea em pacientes com cérato-conjuntivite vernal. [Doctoral Dissertation]. University of São Paulo; 2002. Available from: http://www.teses.usp.br/teses/disponiveis/5/5149/tde-07032002-002915/ ;

2. Gonçalves, Mariana Inês Pereira Coelho. Conjuntivite em animais de companhia.

Degree: 2015, RCAAP

URL: http://www.rcaap.pt/detail.jsp?id=oai:http://repositorio.utad.pt/:10348/5257

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Dissertação de Mestrado Integrado em Medicina Veterinária, Ciências Veterinárias

A conjuntivite é a doença ocular mais frequentemente diagnosticada em Medicina Veterinária, tanto em cães como… (more)

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Dissertação de Mestrado Integrado em Medicina Veterinária, Ciências Veterinárias

A conjuntivite é a doença ocular mais frequentemente diagnosticada em Medicina Veterinária, tanto em cães como em gatos. O facto de a conjuntiva ser uma membrana mucosa tão exposta a agentes externos faz com que esteja bastante suscetível a sofrer lesões, com consequente inflamação. Nesta dissertação abordam-se os diferentes tipos de conjuntivite, que são classificados de acordo com a sua etiologia. No Hospital Veterinário do Baixo Vouga, durante o período de estágio, foram acompanhados diversos casos clínicos de conjuntivite. A seleção dos quatro animais incluídos nesta dissertação teve como intuito eleger uma amostra de casos distintos de conjuntivite, alguns de etiologia bastante frequente e outros de etiologia menos frequente. O primeiro caso clínico refere-se a uma conjuntivite parasitária, por Thelazia spp., num cão; o segundo é um caso de queratoconjuntivite iatrogénica, num cão, secundária à administração de trimetoprim-sulfametoxazol; o terceiro aborda uma conjuntivite neonatal, num gato com infeção respiratória superior; por último é discutido um caso clínico de conjuntivite alérgica, num cão com historial de hipersensibilidade. A conjuntivite é efetivamente uma doença ocular muito frequente em cães e gatos, como se comprovou pelo número de casos observados no Hospital Veterinário do Baixo Vouga, durante o período de estágio. Além disso, a maioria das conjuntivites pode ser eficazmente tratada, sobretudo quando diagnosticada precocemente. Uma boa anamnese e um exame oftalmológico detalhado são, muitas vezes, suficientes para obter um diagnóstico. Em alguns casos é necessária a utilização de outros exames complementares para obter um diagnóstico etiológico, fundamental para se aplicar um tratamento adequado.

Conjunctivitis is the most common ocular disease in Veterinary practice, both in cats and dogs. As the conjunctiva is a mucous membrane such exposed to external agents, it is very susceptible to suffer lesions, with consequent inflamation. In this dissertation different types of conjunctivitis, classified according to their etiology, are discussed. In the Hospital Veterinário do Baixo Vouga several clinical cases of conjunctivitis were followed during the internship period. The selection of the four animals included in this dissertation aimed to elect a sample of different cases of conjunctivitis, some of quite common etiology and other of less common etiology. The first one relates to a parasitic conjunctivitis, for Thelazia spp., in a dog.; the second is a case of iatrogenic keratoconjunctivitis in a dog, secondary to administration of trimethoprim-sulfamethoxazole; the third discusses a neonatal conjunctivitis in a cat with upper respiratory infection; at last a case of allergic conjunctivitis, in a dog with history of hypersensitivity, is discussed. Conjunctivitis is effectively a very common eye disease in dogs and cats, as it was evidenced by the number of cases seen at the Hospital Veterinário do Baixo Vouga,…

Advisors/Committee Members: Pires, Maria João Miranda, Vilhena, Hugo Corte Real.

Subjects/Keywords: Cães; Conjuntivite; Gatos; Oftalmologia veterinária

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Gonçalves, M. I. P. C. (2015). Conjuntivite em animais de companhia. (Thesis). RCAAP. Retrieved from http://www.rcaap.pt/detail.jsp?id=oai:http://repositorio.utad.pt/:10348/5257

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Gonçalves, Mariana Inês Pereira Coelho. “Conjuntivite em animais de companhia.” 2015. Thesis, RCAAP. Accessed January 23, 2021. http://www.rcaap.pt/detail.jsp?id=oai:http://repositorio.utad.pt/:10348/5257.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Gonçalves, Mariana Inês Pereira Coelho. “Conjuntivite em animais de companhia.” 2015. Web. 23 Jan 2021.

Vancouver:

Gonçalves MIPC. Conjuntivite em animais de companhia. [Internet] [Thesis]. RCAAP; 2015. [cited 2021 Jan 23]. Available from: http://www.rcaap.pt/detail.jsp?id=oai:http://repositorio.utad.pt/:10348/5257.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Gonçalves MIPC. Conjuntivite em animais de companhia. [Thesis]. RCAAP; 2015. Available from: http://www.rcaap.pt/detail.jsp?id=oai:http://repositorio.utad.pt/:10348/5257

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

3. Lima, Ana Rachel Vasconcelos de. Situação epidemiológica da filariose linfática no foco endêmico de Maceió-Alagoas após a implantação do programa de eliminação.

Degree: 2007, Universidade Federal de Alagoas

URL: http://www.repositorio.ufal.br/handle/riufal/909

► Lymphatic filariasis is a neglected disease popularly known as elephantiasis because of one of its chronic clinical manifestation. In Maceió, filariasis transmission is restricted to… (more)

▼ Lymphatic filariasis is a neglected disease popularly known as elephantiasis because of one of its chronic clinical manifestation. In Maceió, filariasis transmission is restricted to a well defined area in the city including the contiguous and central ditricts of Feitosa, Jacintinho and Pitanguinha, at the edge of Canal do Reginaldo. In order to assess the epidemiological situation of lymphatic filariasis in Maceió after the implementation of the "Program to Eliminate Lymphatic Filariasis" (PELF) in the city in 1999, hemoscopic and immunological surveys were conducted. For the hemoscopic survey (HS) blood sample was collected by the thick smear (TS) technique after after 9h30 pm, and examined for the presence of circulating microfilariae (mf). Using this technique 53,857 individuals in the endemic area and 9.880 inhabitants in the neighbouring area were examined, aged four years or older. Immunological survey (IS) was carried out using a rapid immunochromatographic card test ("ICT card test") to examine 414 inhabitants of the endemic area and 2,541 in the neighbouring area, being 2,214 individuals between 15 and 25 years and 327 children between 5 and 10 years old. By TS, 182 (0,32%) out of the 53,857 examined individuals in the endemic area presented microfilariae, being the prevalence significantly higher among male than female. It was observed along the years the following frequencies of microfilaraemic carriers: 1999 0.76%; 2000 0.57%; 2001 0.49%; 2002 0.11%; 2003 0.13%; 2004 0.06%. Among 9,880 individuals examined in the neighbouring area, only one (0,01%) microfilaremic carrier was detected. Only one (0,24%) filarial antigen carrier out of 414 examined, were detected. In neighbouring area, 327 children were examined for the "ICT card test", all being antigen-negative, while 2,214 young adults examined, eight (0,36%) presented soluble antigens. The average of microfilariae density of 93.8 ± 149.1 mf/mL blood, is significantly lower than that observed in the same area, in the past decade of 580.5 ± 786 mf/mL. During the study carried out since the implementation of the PELF in Maceió, from 1999 until 2006, the prevalence rates of microfilaraemic diagnosed by TS in the endemic area presented a significant decrease. Analysing the results of examined individuals from the neighbourhood of the endemic area it is evident that filariasis do not spread to the contiguous districts of the endemic focus. The IS carried out in individuals above five years of age in the general population of the endemic area detected very low antigenaemia for Wuchereria bancrofti in 2003. The IS in the neighbouring area carried out in children of 5-10 years old did not detect any individual with circulating antigen of W. bancrofti, whereas in the group of young adults (15-25 years), in this same area, eight individuals were found antigenpositive, being six amicrofilaraemic and two with low microfilaraemia when examined by TS usually employed in big surveys. The results of this study prove that measures used for the elimination of… Advisors/Committee Members: Fontes, Gilberto, CPF:35764376653, FONTES, Gilberto, Rocha, Abraham Cézar de Brito, CPF:34940316491, ROCHA, A. C. B., Miranda, Claudio Torres de, CPF:58659765834, MIRANDA, C. T..

Subjects/Keywords: Filariose linfática; Wuchereria bancrof; Epidemiologia Maceió (AL); Lymphatic filariasis; Epidemiology; Maceió(AL); Wuchereria bancrofti; CNPQ::CIENCIAS DA SAUDE

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Lima, A. R. V. d. (2007). Situação epidemiológica da filariose linfática no foco endêmico de Maceió-Alagoas após a implantação do programa de eliminação. (Masters Thesis). Universidade Federal de Alagoas. Retrieved from http://www.repositorio.ufal.br/handle/riufal/909

Chicago Manual of Style (16^th Edition):

Lima, Ana Rachel Vasconcelos de. “Situação epidemiológica da filariose linfática no foco endêmico de Maceió-Alagoas após a implantação do programa de eliminação.” 2007. Masters Thesis, Universidade Federal de Alagoas. Accessed January 23, 2021. http://www.repositorio.ufal.br/handle/riufal/909.

MLA Handbook (7^th Edition):

Lima, Ana Rachel Vasconcelos de. “Situação epidemiológica da filariose linfática no foco endêmico de Maceió-Alagoas após a implantação do programa de eliminação.” 2007. Web. 23 Jan 2021.

Vancouver:

Lima ARVd. Situação epidemiológica da filariose linfática no foco endêmico de Maceió-Alagoas após a implantação do programa de eliminação. [Internet] [Masters thesis]. Universidade Federal de Alagoas; 2007. [cited 2021 Jan 23]. Available from: http://www.repositorio.ufal.br/handle/riufal/909.

Council of Science Editors:

Lima ARVd. Situação epidemiológica da filariose linfática no foco endêmico de Maceió-Alagoas após a implantação do programa de eliminação. [Masters Thesis]. Universidade Federal de Alagoas; 2007. Available from: http://www.repositorio.ufal.br/handle/riufal/909

Universidade do Rio Grande do Sul

4. Bauer, Lidiane. Estimação do coeficiente de correlação de spearman ponderado.

Degree: 2007, Universidade do Rio Grande do Sul

URL: http://hdl.handle.net/10183/11499

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Para estimar a correlação de duas variáveis que não têm distribuição conjunta normal bivariada, a alternativa mais usual é o coeficiente de correlação de Spearman.… (more)

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Para estimar a correlação de duas variáveis que não têm distribuição conjunta normal bivariada, a alternativa mais usual é o coeficiente de correlação de Spearman. Entretanto, quando os dados necessitam de ponderação na análise, como no caso de delineamentos amostrais complexos, não existe método descrito na literatura para estimar essa correlação. Este artigo propõe dois métodos para este cenário e os compara via simulação Monte Carlo. O primeiro método, chamado de método da amostra expandida, consiste em replicar cada observação da amostra em número igual ao seu peso e calcular o coeficiente de Spearman na amostra expandida. No segundo método, o método dos postos, é estimado o coeficiente de correlação de Pearson ponderado nos postos das duas variáveis. Teste de hipóteses tradicional das estimativas produzidas pelos dois métodos também é abordado neste artigo. Os dois estimadores do coeficiente de Spearman ponderado explorados mostraram desempenhos muito semelhantes, com ausência de viés, pequena variabilidade e mesma eficiência. Entretanto, se recomenda estes métodos quando os dados são medidos em escala. Este trabalho também explora a estimação pontual do coeficiente de Pearson ponderado e estimação de intervalos de confiança bootstrap, quando a suposição de normalidade bivariada está violada. Sua principal vantagem é evitar potencial influência da expansão da amostra nos postos associados aos valores observados como ocorre com o coeficiente de Spearman.

To estimate the correlation of two variables that don’t have bivariate normal distribution, the more usual alternative is the Spearman correlation coefficient. However, when the data need of weighting in the analysis like the complex sample surveys, there aren’t any methods for estimate this correlation in the literature. This paper proposes two methods for this framework and compares it through the Monte Carlo simulation. The first method which will be called of expanded sample method, consist of replied each observation from sample by its correspondent weight in it. In the second method, called of ranks methods, the ranks of the two variables are calculated, and then are estimated the weighted Pearson correlation coefficient. This work also explores another solution for making inference to the Pearson coefficient in the presence of weighting and violation of the assumption of normality, the bootstrap confidence interval. The two estimators proposed showed performance very similar, with or without bias and a little variability. However, a more current proceeding is to estimate the weighted Pearson correlation coefficient and to construct a bootstrap confidence interval, because in this way is unnecessary to know the joint distribution of the two variables. It is important to point out that to Pearson coefficient there is no loss of information in its calculation like in the Spearman coefficient, once in the last one are considerate just the ranks.

Advisors/Committee Members: Vigo, Álvaro.

Subjects/Keywords: Epidemiologia

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Bauer, L. (2007). Estimação do coeficiente de correlação de spearman ponderado. (Thesis). Universidade do Rio Grande do Sul. Retrieved from http://hdl.handle.net/10183/11499

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Bauer, Lidiane. “Estimação do coeficiente de correlação de spearman ponderado.” 2007. Thesis, Universidade do Rio Grande do Sul. Accessed January 23, 2021. http://hdl.handle.net/10183/11499.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Bauer, Lidiane. “Estimação do coeficiente de correlação de spearman ponderado.” 2007. Web. 23 Jan 2021.

Vancouver:

Bauer L. Estimação do coeficiente de correlação de spearman ponderado. [Internet] [Thesis]. Universidade do Rio Grande do Sul; 2007. [cited 2021 Jan 23]. Available from: http://hdl.handle.net/10183/11499.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Bauer L. Estimação do coeficiente de correlação de spearman ponderado. [Thesis]. Universidade do Rio Grande do Sul; 2007. Available from: http://hdl.handle.net/10183/11499

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Helsinki

5. Lamagni, Theresa. The epidemiology of severe Streptococcus pyogenes disease in Europe.

Degree: Haartman Institute, Department of Bacteriology and Immunology; Health Protection Agency Centre for Infections, London UK; Department of Bacterial and Inflammatory Diseases, National Public Health Institute, Helsinki, Finland., 2008, University of Helsinki

URL: http://hdl.handle.net/10138/20461

► Diseases caused by the Lancefield group A streptococcus, Streptococcus pyogenes, are amongst the most challenging to clinicians and public health specialists alike. Although severe infections… (more)

▼ Diseases caused by the Lancefield group A streptococcus, Streptococcus pyogenes, are amongst the most challenging to clinicians and public health specialists alike. Although severe infections caused by S. pyogenes are relatively uncommon, affecting around 3 per 100,000 of the population per annum in developed countries, the case fatality is high relative to many other infections. Despite a long scientific tradition of studying their occurrence and characteristics, many aspects of their epidemiology remain poorly understood, and potential control measures undefined. Epidemiological studies can play an important role in identifying host, pathogen and environmental factors associated with risk of disease, manifestation of particular syndromes or poor survival. This can be of value in targeting prevention activities, as well directing further basic research, potentially paving the way for the identification of novel therapeutic targets. The formation of a European network, Strep-EURO, provided an opportunity to explore epidemiological patterns across Europe. Funded by the Fifth Framework Programme of the European Commission s Directorate-General for Research (QLK2.CT.2002.01398), the Strep-EURO network was launched in September 2002. Twelve participants across eleven countries took part, led by the University of Lund in Sweden. Cases were defined as patients with S. pyogenes isolated from a normally sterile site, or non-sterile site in combination with clinical signs of streptococcal toxic shock syndrome (STSS). All participating countries undertook prospective enhanced surveillance between 1st January 2003 and 31st December 2004 to identify cases diagnosed during this period. A standardised surveillance dataset was defined, comprising demographic, clinical and risk factor information collected through a questionnaire. Isolates were collected by the national reference laboratories and characterised according to their M protein using conventional serological and emm gene typing. Descriptive statistics and multivariable analyses were undertaken to compare characteristics of cases between countries and identify factors associated with increased risk of death or development of STSS. Crude and age-adjusted rates of infection were calculated for each country where a catchment population could be defined. The project succeeded in establishing the first European surveillance network for severe S. pyogenes infections, with 5522 cases identified over the two years. Analysis of data gathered in the eleven countries yielded important new information on the epidemiology of severe S. pyogenes infections in Europe during the 2000s. Comprehensive epidemiological data on these infections were obtained for the first time from France, Greece and Romania. Incidence estimates identified a general north-south gradient, from high to low. Remarkably similar age-standardised rates were observed among the three Nordic participants, between 2.2 and 2.3 per 100,000 population. Rates in the UK were higher still, 2.9/100,000, elevated by an…

Subjects/Keywords: epidemiologia; epidemiologia

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Lamagni, T. (2008). The epidemiology of severe Streptococcus pyogenes disease in Europe. (Doctoral Dissertation). University of Helsinki. Retrieved from http://hdl.handle.net/10138/20461

Chicago Manual of Style (16^th Edition):

Lamagni, Theresa. “The epidemiology of severe Streptococcus pyogenes disease in Europe.” 2008. Doctoral Dissertation, University of Helsinki. Accessed January 23, 2021. http://hdl.handle.net/10138/20461.

MLA Handbook (7^th Edition):

Lamagni, Theresa. “The epidemiology of severe Streptococcus pyogenes disease in Europe.” 2008. Web. 23 Jan 2021.

Vancouver:

Lamagni T. The epidemiology of severe Streptococcus pyogenes disease in Europe. [Internet] [Doctoral dissertation]. University of Helsinki; 2008. [cited 2021 Jan 23]. Available from: http://hdl.handle.net/10138/20461.

Council of Science Editors:

Lamagni T. The epidemiology of severe Streptococcus pyogenes disease in Europe. [Doctoral Dissertation]. University of Helsinki; 2008. Available from: http://hdl.handle.net/10138/20461

Technical University of Lisbon

6. Lourenço, Maria do Guadalupe Mègre Pires de Carvalho. Avaliação da osmolaridade da lágrima em cães atópicos com conjuntivite alérgica.

Degree: 2013, Technical University of Lisbon

URL: http://www.rcaap.pt/detail.jsp?id=oai:www.repository.utl.pt:10400.5/6096

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Dissertação de Mestrado Integrado em Medicina Veterinária

A osmolaridade do filme lacrimal é um parâmetro útil para avaliar a qualidade da lágrima. Esta representa a… (more)

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Dissertação de Mestrado Integrado em Medicina Veterinária

A osmolaridade do filme lacrimal é um parâmetro útil para avaliar a qualidade da lágrima. Esta representa a concentração de catiões (sódio, potássio, cálcio, magnésio, ferro e cobre) e de aniões (cloretos, carbonatos e fosfatos) dissolvidos na porção aquosa da lágrima. O objectivo deste estudo é avaliar a osmolaridade do filme lacrimal em cães atópicos com conjuntivite alérgica (CA). A CA é muito prevalente nos cães que têm dermatite atópica (DA). No entanto esta afeção é um diagnóstico de exclusão, pois não existe um teste simples e eficaz para a diagnosticar. Foi incluído no estudo um grupo controlo (n=20) e um grupo de cães atópicos com sinais de CA (n=20). Todos os animais foram sujeitos a exame dermatológico, bem como a exame oftálmico para avaliação dos sinais clínicos de CA (quemose, prurido, epífora, hiperémia conjuntival, corrimento ocular e presença de doença da córnea) e sua classificação numa escala de 0-3. Adicionalmente o grupo dos atópicos foi classificado segundo a escala CADESI-03. Avaliou-se a osmolaridade do filme lacrimal com o sistema TearLab osmolarity® (TearLab Corp., San Diego, E.U.A.). O estudo estatístico foi realizado com GraphPad Instat® recorrendo aos testes de Mann- Whitney e regressão linear. Após avaliação dos dados, a osmolaridade do filme lacrimal apresentou um valor médio de 320,8±9,6 mOsm/L no grupo controlo e 340,3±21,6 mOsm/L no grupo de animais atópicos. Os valores de osmolaridade dos dois grupos apresentaram diferenças estatísticas extremamente significativas (P<0,1%; teste Mann-Whitney). Não se encontraram diferenças significativas entre a osmolaridade da lágrima do olho direito e do olho esquerdo no grupo controlo (P=0,5244; teste Mann-Whitney) nem no grupo atópico (P=0,123; teste Mann- Whitney). Nos pacientes atópicos o valor de CADESI-03 médio foi de 180,1±66,50 valores e o score de CA foi 8,2±2,36 valores. A osmolaridade dos cães atópicos e os seus CADESI-03 exibiram uma correlação estatística extremamente significativa (P<0,1%; teste de regressão linear). Pelo contrário, não se encontrou uma correlação estatistica significativa entre a osmolaridade dos cães atópicos e o score de CA (P=0,8385; teste de regressão linear). Podemos concluir que a osmolaridade da lágrima se encontra alterada nos cães atópicos afetados por CA. Esta informação é útil tanto para diagnóstico de CA como para avaliação da resposta à terapêutica. Poderá também ter interesse quando consideramos o cão como potencial modelo de CA no Homem.

ABSTRACT - TEAR FILM OSMOLARITY EVALUATION IN ATOPIC DOGS WITH ALLERGIC CONJUNCTIVITIS - Tear film osmolarity is a crucial parameter to evaluate tear’s quality. It represents cation (sodium, potassium, calcium, magnesium, iron and copper) and anion (chlorides, carbonates, and phosphates) concentration in the tear’s aqueous portion. The goal of this study is to evaluate the osmolarity of the tear film in atopic dogs with allergic conjunctivitis. The majority of dogs, which suffer from atopic dermatitis,…

Advisors/Committee Members: Lourenço, Ana Mafalda Gonçalves Xavier Felix, Delgado, Esmeralda Sofia Costa.

Subjects/Keywords: Conjuntivite alérgica; Osmolaridade; Tearlab osmolarity ®; Allergic conjunctivitis; Osmolarity

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Lourenço, M. d. G. M. P. d. C. (2013). Avaliação da osmolaridade da lágrima em cães atópicos com conjuntivite alérgica. (Thesis). Technical University of Lisbon. Retrieved from http://www.rcaap.pt/detail.jsp?id=oai:www.repository.utl.pt:10400.5/6096

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Lourenço, Maria do Guadalupe Mègre Pires de Carvalho. “Avaliação da osmolaridade da lágrima em cães atópicos com conjuntivite alérgica.” 2013. Thesis, Technical University of Lisbon. Accessed January 23, 2021. http://www.rcaap.pt/detail.jsp?id=oai:www.repository.utl.pt:10400.5/6096.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Lourenço, Maria do Guadalupe Mègre Pires de Carvalho. “Avaliação da osmolaridade da lágrima em cães atópicos com conjuntivite alérgica.” 2013. Web. 23 Jan 2021.

Vancouver:

Lourenço MdGMPdC. Avaliação da osmolaridade da lágrima em cães atópicos com conjuntivite alérgica. [Internet] [Thesis]. Technical University of Lisbon; 2013. [cited 2021 Jan 23]. Available from: http://www.rcaap.pt/detail.jsp?id=oai:www.repository.utl.pt:10400.5/6096.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Lourenço MdGMPdC. Avaliação da osmolaridade da lágrima em cães atópicos com conjuntivite alérgica. [Thesis]. Technical University of Lisbon; 2013. Available from: http://www.rcaap.pt/detail.jsp?id=oai:www.repository.utl.pt:10400.5/6096

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universidade Federal de Viçosa

7. Euldes Nei Rosado Filho. Prevalência de adenovírus como agente causador de conjuntivite em clínica médica oftalmológica especializada nos anos de 2009 e 2010.

Degree: 2011, Universidade Federal de Viçosa

URL: http://www.tede.ufv.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=4156

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The adenovirus (AdV) is one of the most common etiological agents of conjunctivitis, being associated with outbreaks and epidemics of fast widespread conjunctivitis and might… (more)

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The adenovirus (AdV) is one of the most common etiological agents of conjunctivitis, being associated with outbreaks and epidemics of fast widespread conjunctivitis and might also cause upper respiratory tract infections, cystitis, gastroenteritis and scenarios of more serious infections such as pneumonia and myocarditis. The viral conjunctivitis shows up as redness in the eyes, tearing, watery eye, photophobia, ocular discomfort and often also as visual impairment due to keratitis/keratopathy. In this study, it had been sought to assess the prevalence of the adenovirus as the etiological agent of conjunctivitis in an ophthalmological clinic in the city of Viçosa, Minas Gerais, Brazil, from January 2009 to December 2010. Serotypes present in 11 positive randomly selected samples have been characterized by sequencing and genotyping. In order to define the frequency of adenovirus as the etiological agent of conjunctivitis, samples were collected from the conjunctival secretion of 91patients. After DNA extraction, samples were subjected to PCR with primers specific for Adenovirus. Samples that had the adenovirus, there has been an amplification of a band of 301 bp, corresponding to a part of the structural gene II protein, hexoncapsid, common to multiple adenoviruses. Based on the findings of evolution and ophthalmological examination with slit-lamp serial biomicroscopy, there was clinical suspicion of Adenovirus prevalence of 43.68%. The results of the PCR test showed a prevalence of Adenovirus in 36.3% of the samples. Eleven PCR + samples were sequenced, revealing the presence of serotypes 8, 4, 7, 3, 34 and one unclassified in group D. The presence of serotypes 8, 4, 3 and 34 was not surprising, however, of serotype 7 (group B) was unexpected, because there are reports associated with cases of unfavourable and fatal infection evolution, caused by variants of this type, due pneumonia and myocarditis. The presence of adenovirus in conjunctival secretion indentified through PCR allows a precise diagnosis, and avoiding unnecessary and expensive antibiotics, permitting restrictive measures of contact and dissemination and warning of the presence of more aggressive serotypes causing epidemic keratoconjunctivitis, among other etiological agents of pneumonia, myocarditis and gastroenteritis.

O Adenovírus (AdV) é um dos agentes etiológicos mais frequente da conjuntivite; está associado a surtos e epidemias de conjuntivite com rápida disseminação, podendo também causar infecções em vias áreas superiores (IVAS), cistite, gastroenterite e quadros de infecção mais grave como pneumonia e miocardite. As conjuntivites virais manifestam-se como vermelhidão nos olhos, lacrimejamento, secreção ocular aquosa, fotofobia, desconforto ocular e com frequência também com baixa visual decorrente de ceratite. Neste trabalho, procurou-se aferir a prevalência do Adenovírus como agente causador de conjuntivite em uma clínica oftalmológica localizada na cidade de Viçosa, Minas Gerais, no período de janeiro de 2009 a dezembro de 2010.…

Advisors/Committee Members: Sérgio Oliveira de Paula, Clóvis Andrade Neves, Eduardo de Almeida Marques da Silva, Cynthia Canedo da Silva, Leandro Licursi de Oliveira.

Subjects/Keywords: Adenovírus; Conjuntivite; PCR; BIOLOGIA GERAL; Adenovirus; Conjunctivitis; PCR

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Filho, E. N. R. (2011). Prevalência de adenovírus como agente causador de conjuntivite em clínica médica oftalmológica especializada nos anos de 2009 e 2010. (Thesis). Universidade Federal de Viçosa. Retrieved from http://www.tede.ufv.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=4156

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Filho, Euldes Nei Rosado. “Prevalência de adenovírus como agente causador de conjuntivite em clínica médica oftalmológica especializada nos anos de 2009 e 2010.” 2011. Thesis, Universidade Federal de Viçosa. Accessed January 23, 2021. http://www.tede.ufv.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=4156.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Filho, Euldes Nei Rosado. “Prevalência de adenovírus como agente causador de conjuntivite em clínica médica oftalmológica especializada nos anos de 2009 e 2010.” 2011. Web. 23 Jan 2021.

Vancouver:

Filho ENR. Prevalência de adenovírus como agente causador de conjuntivite em clínica médica oftalmológica especializada nos anos de 2009 e 2010. [Internet] [Thesis]. Universidade Federal de Viçosa; 2011. [cited 2021 Jan 23]. Available from: http://www.tede.ufv.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=4156.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Filho ENR. Prevalência de adenovírus como agente causador de conjuntivite em clínica médica oftalmológica especializada nos anos de 2009 e 2010. [Thesis]. Universidade Federal de Viçosa; 2011. Available from: http://www.tede.ufv.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=4156

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universidade do Rio Grande do Sul

8. Porto Neto, Arnaldo Carlos. Fatores de risco para asma e rinite alérgica em população de escolares na cidade de Passo Fundo, RS.

Degree: 2012, Universidade do Rio Grande do Sul

URL: http://hdl.handle.net/10183/67518

► Introdução: nas últimas décadas, tem havido aumento na prevalência das doenças alérgicas, como também na sensibilização a aeroalérgenos ou alimentos, fenômenos caracterizados como “epidemia das… (more)

▼ Introdução: nas últimas décadas, tem havido aumento na prevalência das doenças alérgicas, como também na sensibilização a aeroalérgenos ou alimentos, fenômenos caracterizados como “epidemia das doenças alérgicas”. Objetivo: determinar os fatores de risco associados a sintomas de asma (sibilância) e rinoconjuntivite, descrevendo a prevalência desses sintomas em crianças escolares do município de Passo Fundo, RS. Método: estudo transversal realizado em alunos de oito a doze anos de idade matriculados em escolas públicas e particulares do ensino fundamental, moradores da zona urbana de Passo Fundo, RS. A amostra representativa dessa população foi escolhida aleatoriamente, e seus pais ou responsáveis responderam questionário escrito padrão do International Study of Asthma and Allergies in Childhood (ISAAC), acrescido de perguntas sobre fatores de risco pessoais, familiares e ambientais (ISAAC fase II). Dessa população inicial, separou-se, aleatoriamente, um subgrupo de crianças (n=878), para realizar testes cutâneos de hipersensibilidade imediata (TCHIs) com alérgenos ambientais e coletar amostras de fezes para exame protoparasitológico. As crianças também foram pesadas, tendo sua estatura aferida e seu índice de massa corporal (IMC) calculado. Resultados: a prevalência de asma ativa foi de 31,2%; de asma diagnosticada, de 16,3%; de asma induzida por exercício, de 14,1%; de asma grave, de 7,4%; de crise aguda severa de asma, de 5,6%. A prevalência de rinite ativa foi de 53%; rinoconjuntivite, 37,6%; rinite diagnosticada, 35%; rinite polínica (hay fever), 27,9%; rinite moderada a grave, 14,7%. A prevalência de eczema ativo foi de 17,8%; de eczema em dobras, 16,8%; de eczema grave, 2,7%. Eram atópicos 487/878 (55,5%), independentemente de serem asmáticos ou não; desses, 84,4% eram polissensibilizados. A maioria (70,2%) dos que tinham asma atual era atópica, sendo somente 9% monossensibilizados. Da mesma maneira, a maioria (83,1%) dos com asma ativa também era atópica (OR = 3,16; IC95%=4,4-7,6). Além disso, os asmáticos atópicos tinham asma mais grave em relação aos não atópicos (OR = 2,39; IC95% = 2,60-7,60). Os fatores de risco siginificativamente associados à asma ativa foram: história materna de asma (OR = 1,75, IC 95%= 1,05-2,87), rinite ativa (OR = 2,07, IC 95%=1,42-3,01), compartilhar quarto no primeiro ano de vida (OR = 2,03, IC 95%= 1,36-3,04), ser atópico (OR = 1,82, IC 95%=1,26-2,50), ter contato com gato intradomiciliar no primeiro ano de vida (OR = 1,73, IC 95%=1,07-2,78), usar paracetamol mais de 12× ao ano nos últimos doze meses (OR=1,68, IC 95= 1,20-2,31)), usar antibiótico com ≤6 meses de vida (OR = 1,57, IC 95%= 1,13-2,17), ter tido bronquiolite com ≤2 anos de vida (OR = 3,11, IC 95%=2,23-4,33), ter nascido de parto prematuro (OR = 1,60, IC 95%=1,02-2,50). Em relação à rinoconjuntivite, os fatores de risco foram: história de eczema no pai (OR = 3,50, IC 95%= 1,05-10,70), rinite no pai (OR= 1,73, IC 95%=1,06-2,82), residência com mofo (OR = 2,09, IC 95%=1,16-3,74), ter morado em casa úmida no primeiro ano… Advisors/Committee Members: Menna Barreto, Sérgio Saldanha.

Subjects/Keywords: Asma; Asthma; Conjuntivite alérgica; Rhinoconjunctivitis; Rinite; Rhinitis; Children; Criança; Prevalence; Risk factors; ISAAC; Epidemiology

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Porto Neto, A. C. (2012). Fatores de risco para asma e rinite alérgica em população de escolares na cidade de Passo Fundo, RS. (Thesis). Universidade do Rio Grande do Sul. Retrieved from http://hdl.handle.net/10183/67518

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Porto Neto, Arnaldo Carlos. “Fatores de risco para asma e rinite alérgica em população de escolares na cidade de Passo Fundo, RS.” 2012. Thesis, Universidade do Rio Grande do Sul. Accessed January 23, 2021. http://hdl.handle.net/10183/67518.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Porto Neto, Arnaldo Carlos. “Fatores de risco para asma e rinite alérgica em população de escolares na cidade de Passo Fundo, RS.” 2012. Web. 23 Jan 2021.

Vancouver:

Porto Neto AC. Fatores de risco para asma e rinite alérgica em população de escolares na cidade de Passo Fundo, RS. [Internet] [Thesis]. Universidade do Rio Grande do Sul; 2012. [cited 2021 Jan 23]. Available from: http://hdl.handle.net/10183/67518.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Porto Neto AC. Fatores de risco para asma e rinite alérgica em população de escolares na cidade de Passo Fundo, RS. [Thesis]. Universidade do Rio Grande do Sul; 2012. Available from: http://hdl.handle.net/10183/67518

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universidade Estadual de Campinas

9. Pinto, Roberto Damian Pacheco, 1984-. Ensaio clínico randomizado de dexametasona 0,1%/iodo-povidine 0,4% versus lágrimas artificiais no tratamento da conjuntivite viral aguda presumida: Dexamethasone/povidone eye drops versus artificial tears for treatment of presumed viral conjunctivitis : a randomized clinical trial - dexamethasone/povidone for conjunctivitis.

Degree: 2015, Universidade Estadual de Campinas

URL: http://repositorio.unicamp.br/jspui/handle/REPOSIP/313026

► Abstract: Purpose: To determine whether topical dexamethasone 0.1%/povidone-iodine 0.4% reduces the duration of presumed viral conjunctivitis better than artificial tears and whether the treatment relieves… (more)

▼ Abstract: Purpose: To determine whether topical dexamethasone 0.1%/povidone-iodine 0.4% reduces the duration of presumed viral conjunctivitis better than artificial tears and whether the treatment relieves the symptoms of this disease. Design: It¿s a randomized, masked, controlled trial. Methods: One hundred and twenty-two patients with a clinical diagnosis of presumed viral conjunctivitis were randomized to either the treatment group or the control group. Physicians and patients were masked to the treatment. Swabs were taken from the conjunctival fornix for adenovirus PCR analyses. Patients in the treatment group received topical dexamethasone 0.1%/povidone-iodine 0.4% eye drops four times daily, and patients in the placebo group received artificial tears four times daily, both for seven days. Symptoms were recorded on the day of recruitment and at the time of a follow-up examination 5, 10 and 30 days later. The main outcome was duration of the disease. The others outcomes were overall discomfort, itching, foreign body sensation, tearing, redness, eyelid swelling, side effects of the eye drops, intraocular pressure and the incidence of subepithelial corneal infiltrates. Results: There was no statistically significant difference between the treatment group and the control group in terms of the patients¿ symptoms, intraocular pressure, and incidence of subepithelial cornea infiltrates during the entire follow-up period. Patients of the treatment group reported more stinging (p<.001) and a shorter conjunctivitis duration (9.4±4.6 days in the dexamethasone 0.1%/povidone-iodine 0.4% group versus 11.8±4.9 days in the artificial tears group, p=.009). Conclusion: The use of topical dexamethasone 0.1%/povidone-iodine 0.4% eye drops four times daily appears to reduce the duration of conjunctivitis, although it causes more stinging than artificial tears Advisors/Committee Members: UNIVERSIDADE ESTADUAL DE CAMPINAS (CRUESP), Lira, Rodrigo Pessoa Cavalcanti, 1973- (advisor), Arieta, Carlos Eduardo Leite, 1956- (coadvisor), Universidade Estadual de Campinas. Faculdade de Ciências Médicas (institution), Programa de Pós-Graduação em Ciências Médicas (nameofprogram), Jorge, Eliane Chaves (committee member), Rocha, Eduardo Melani (committee member), Vasconcellos, Jose Paulo Cabral de (committee member), Carvalheira, José Barreto Campello (committee member).

Subjects/Keywords: Dexametasona; Adenovírus humanos; Conjuntivite; Povidona-iodo; Dexamethasone; Adenoviruses, Human; Conjunctivitis; Povidone-Iodine

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Pinto, Roberto Damian Pacheco, 1. (2015). Ensaio clínico randomizado de dexametasona 0,1%/iodo-povidine 0,4% versus lágrimas artificiais no tratamento da conjuntivite viral aguda presumida: Dexamethasone/povidone eye drops versus artificial tears for treatment of presumed viral conjunctivitis : a randomized clinical trial - dexamethasone/povidone for conjunctivitis. (Thesis). Universidade Estadual de Campinas. Retrieved from http://repositorio.unicamp.br/jspui/handle/REPOSIP/313026

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Pinto, Roberto Damian Pacheco, 1984-. “Ensaio clínico randomizado de dexametasona 0,1%/iodo-povidine 0,4% versus lágrimas artificiais no tratamento da conjuntivite viral aguda presumida: Dexamethasone/povidone eye drops versus artificial tears for treatment of presumed viral conjunctivitis : a randomized clinical trial - dexamethasone/povidone for conjunctivitis.” 2015. Thesis, Universidade Estadual de Campinas. Accessed January 23, 2021. http://repositorio.unicamp.br/jspui/handle/REPOSIP/313026.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Pinto, Roberto Damian Pacheco, 1984-. “Ensaio clínico randomizado de dexametasona 0,1%/iodo-povidine 0,4% versus lágrimas artificiais no tratamento da conjuntivite viral aguda presumida: Dexamethasone/povidone eye drops versus artificial tears for treatment of presumed viral conjunctivitis : a randomized clinical trial - dexamethasone/povidone for conjunctivitis.” 2015. Web. 23 Jan 2021.

Vancouver:

Pinto, Roberto Damian Pacheco 1. Ensaio clínico randomizado de dexametasona 0,1%/iodo-povidine 0,4% versus lágrimas artificiais no tratamento da conjuntivite viral aguda presumida: Dexamethasone/povidone eye drops versus artificial tears for treatment of presumed viral conjunctivitis : a randomized clinical trial - dexamethasone/povidone for conjunctivitis. [Internet] [Thesis]. Universidade Estadual de Campinas; 2015. [cited 2021 Jan 23]. Available from: http://repositorio.unicamp.br/jspui/handle/REPOSIP/313026.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Pinto, Roberto Damian Pacheco 1. Ensaio clínico randomizado de dexametasona 0,1%/iodo-povidine 0,4% versus lágrimas artificiais no tratamento da conjuntivite viral aguda presumida: Dexamethasone/povidone eye drops versus artificial tears for treatment of presumed viral conjunctivitis : a randomized clinical trial - dexamethasone/povidone for conjunctivitis. [Thesis]. Universidade Estadual de Campinas; 2015. Available from: http://repositorio.unicamp.br/jspui/handle/REPOSIP/313026

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Helsinki

10. Kataja-Tuomola, Merja. Antioxidants, weight change and risk of type 2 diabetes.

Degree: Hjelt Institute; National Institute for Health and Welfare, 2011, University of Helsinki

URL: http://hdl.handle.net/10138/26422

► The incidence of type 2 diabetes has increased rapidly worldwide. Obesity is one of the most important modifiable risk factors of type 2 diabetes: weight… (more)

▼ The incidence of type 2 diabetes has increased rapidly worldwide. Obesity is one of the most important modifiable risk factors of type 2 diabetes: weight gain increases and weight loss decreases the risk. However, the effects of weight fluctuation are unclear. Reactive oxygen species are presumably part of the complicated mechanism for the development of insulin resistance and beta-cell destruction in the pancreas. The association of antioxidants with the risk of incident type 2 diabetes has been studied in longitudinal prospective human studies, but so far there is no clear conclusion about protective effect of dietary or of supplementary antioxidants on diabetes risk. The present study examined 1) weight change and fluctuation as risk factors for incident type 2 diabetes; 2) the association of baseline serum alpha-tocopherol or beta-carotene concentration and dietary intake of antioxidants with the risk of type 2 diabetes; 3) the effect of supplementation with alpha-tocopherol or beta-carotene on the risk of incident type 2 diabetes; and on macrovascular complications and mortality among type 2 diabetics. This investigation was part of the Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study, a randomized, double-blind, placebo-controlled prevention trial, which has undertaken to examine the effect of alpha-tocopherol and beta-carotene supplementation on the development of lung cancer, other cancers, and cardiovascular diseases in male smokers aged 50-69 years at baseline. Participants were assigned to receive either 50 mg alpha-tocopherol, 20mg beta-carotene, both, or placebo daily in a 2 x 2 factorial design experiment during 1985-1993. Cases of incident diabetes were identified through a nationwide register of drug reimbursements of the Social Insurance Institution. At baseline 1700 men had a history of diabetes. Among those (n = 27 379) with no diabetes at baseline 305 new cases of type 2 diabetes were recognized during the intervention period and 705 during the whole follow-up to 12.5 years. Weight gain and weight fluctuation measured over a three year period were independent risk factors for subsequent incident type 2 diabetes. Relative risk (RR) was 1.77 (95% confidence interval [CI] 1.44-2.17) for weight gain of at least 4 kg compared to those with a weight change of less than 4 kg. The RR in the highest weight fluctuation quintile compared to the lowest was 1.64 (95% CI 1.24-2.17). Dietary tocopherols and tocotrienols as well as dietary carotenoids, flavonols, flavones and vitamin C were not associated with the risk of type 2 diabetes. Baseline serum alpha-tocopherol and beta-carotene concentrations were not associated with the risk of incident diabetes. Neither alpha-tocopherol nor beta-carotene supplementation affected the risk of diabetes. The relative risks for participants who received alpha-tocopherol compared with nonrecipients and for participants who received beta-carotene compared with nonrecipients were 0.92 (95% CI 0.79-1.07) and 0.99 (95% CI 0.85-1.15), respectively.…

Subjects/Keywords: lääketiede, epidemiologia; lääketiede, epidemiologia

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Kataja-Tuomola, M. (2011). Antioxidants, weight change and risk of type 2 diabetes. (Doctoral Dissertation). University of Helsinki. Retrieved from http://hdl.handle.net/10138/26422

Chicago Manual of Style (16^th Edition):

Kataja-Tuomola, Merja. “Antioxidants, weight change and risk of type 2 diabetes.” 2011. Doctoral Dissertation, University of Helsinki. Accessed January 23, 2021. http://hdl.handle.net/10138/26422.

MLA Handbook (7^th Edition):

Kataja-Tuomola, Merja. “Antioxidants, weight change and risk of type 2 diabetes.” 2011. Web. 23 Jan 2021.

Vancouver:

Kataja-Tuomola M. Antioxidants, weight change and risk of type 2 diabetes. [Internet] [Doctoral dissertation]. University of Helsinki; 2011. [cited 2021 Jan 23]. Available from: http://hdl.handle.net/10138/26422.

Council of Science Editors:

Kataja-Tuomola M. Antioxidants, weight change and risk of type 2 diabetes. [Doctoral Dissertation]. University of Helsinki; 2011. Available from: http://hdl.handle.net/10138/26422

University of Helsinki

11. Tikkanen, Emmi. Genetic risk profiles for coronary heart disease.

Degree: Hjelt Institute; Suomen molekyylilääketieteen instituutti (FIMM), 2013, University of Helsinki

URL: http://hdl.handle.net/10138/41578

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Coronary heart disease (CHD) is a major burden for public health worldwide. Several factors are known to be associated with the disease risk, including high… (more)

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Coronary heart disease (CHD) is a major burden for public health worldwide. Several factors are known to be associated with the disease risk, including high levels of low-density lipoprotein (LDL) cholesterol and blood pressure. The established risk factors do not, however, fully predict an individual s risk for the disease. In recent years, new candidate risk factors, including genetic markers, have been extensively studied. Genome-wide association studies (GWASs) have mapped over 40 genetic regions for CHD risk and hundreds of loci for CHD risk factors. The impact of these findings on public health remains obscure. In this study, we utilized the findings from large-scale GWASs and constructed genetic risk scores (GRSs) based on panels of single-nucleotide polymorphisms (SNPs). The aim was to estimate the joint effects of common genetic markers on CHD and its risk factors, and to evaluate the incremental value of genetic information in CHD risk assessment. In Projects I and II, we studied longitudinal effects of genetic loci associated with lipids and blood pressure, and evaluated the prediction of dyslipidemia and hypertension in young adults by using the genetic information in addition to clinical measurements. Our results show that the GRSs were significantly associated with longitudinal measurements of lipid traits and blood pressure throughout childhood, adolescence and adulthood. For some traits, the genetic effect was not consistent across age groups. For example, the GRS effect for high-density lipoprotein (HDL) cholesterol was considerably larger in children than in adults, and the proportion of variance explained by the SNPs in children was twice as much as in adults. The GRS for triglycerides improved the prediction of dyslipidemia in young adults when added to childhood lipid measurement. The blood pressure GRS increased the risk of hypertension, but did not improve risk discrimination over other risk factors. In Projects III and IV, we found that the GRSs based on CHD SNPs predicted CHD events. The estimated relative risk for the GRS was similar in magnitude to the relative risk of other risk factors such as systolic blood pressure. The genetic effect was independent of family history of the disease, which has been used as a surrogate for genetic risk in many prediction algorithms. The GRS based on 28 SNPs improved the prediction of CHD events beyond traditional risk factors and family history when evaluated with reclassification or discrimination metrics. Genetic screening could be especially useful for individuals in the intermediate-risk group (10-year risk 10-20%), as current preventive strategies are focused mainly on the high-risk group (>20%). In conclusion, these findings suggest that the genetic information obtained from GWASs could be used in early identification of individuals at increased risk for lipid disorders, hypertension and CHD. Keywords: cardiovascular disease, genetic association, genetic epidemiology, risk factor

Sydänsairaudet muodostavat yhden suurimmista…

Subjects/Keywords: geneettinen epidemiologia; geneettinen epidemiologia

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Tikkanen, E. (2013). Genetic risk profiles for coronary heart disease. (Doctoral Dissertation). University of Helsinki. Retrieved from http://hdl.handle.net/10138/41578

Chicago Manual of Style (16^th Edition):

Tikkanen, Emmi. “Genetic risk profiles for coronary heart disease.” 2013. Doctoral Dissertation, University of Helsinki. Accessed January 23, 2021. http://hdl.handle.net/10138/41578.

MLA Handbook (7^th Edition):

Tikkanen, Emmi. “Genetic risk profiles for coronary heart disease.” 2013. Web. 23 Jan 2021.

Vancouver:

Tikkanen E. Genetic risk profiles for coronary heart disease. [Internet] [Doctoral dissertation]. University of Helsinki; 2013. [cited 2021 Jan 23]. Available from: http://hdl.handle.net/10138/41578.

Council of Science Editors:

Tikkanen E. Genetic risk profiles for coronary heart disease. [Doctoral Dissertation]. University of Helsinki; 2013. Available from: http://hdl.handle.net/10138/41578

University of Helsinki

12. Kaila-Kangas, Leena. Socioeconomic Status, Occupational Factors and Lifestyle as Predictors of Hospitalisation for Back Disorders.

Degree: Department of Public Health; Finnish Institute of Occupational Health, Doctoral Programmes of Public Health, 2006, University of Helsinki

URL: http://hdl.handle.net/10138/20338

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The aim of this dissertation was to examine the determinants of severe back disorders leading to hospital admission in Finland. First, back-related hospitalisations were considered… (more)

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The aim of this dissertation was to examine the determinants of severe back disorders leading to hospital admission in Finland. First, back-related hospitalisations were considered from the perspective of socioeconomic status, occupation, and industry. Secondly, the significance of psychosocial factors at work, sleep disturbances, and such lifestyle factors as smoking and overweight was studied as predictors of hospitalisation due to back disorders. Two sets of data were used: 1) the population-based data comprised all occupationally active Finns aged 25-64, and included hospitalisations due to back disorders in 1996 and 2) a cohort of employees followed up from 1973 to 2000 having been hospitalised due to back disorders. The results of the population-based study showed that people in physically strenuous industries and occupations, such as agriculture and manufacturing, were at an increased risk of being hospitalised for back disorders. The lowest hospitalisation rates were found in sedentary occupations. Occupational class and the level of formal education were independently associated with hospitalisation for back disorders. This stratification was fairly consistent across age-groups and genders. Men had a slightly higher risk of becoming hospitalised compared with women, and the risk increased with age among both genders. The results of the prospective cohort study showed that psychosocial factors at work such as low job control and low supervisor support predicted subsequent hospitalisation for back disorders even when adjustments were made for occupational class and physical workload history. However, psychosocial factors did not predict hospital admissions due to intervertebral disc disorders; only admissions due to other back disorders. Smoking and overweight predicted, instead, only hospitalisation for intervertebral disc disorders. These results suggest that the etiological factors of disc disorders and other back disorders differ from each other. The study concerning the association of sleep disturbances and other distress symptoms with hospitalisation for back disorders revealed that sleep disturbances predicted subsequent hospitalisation for all back disorders after adjustment for chronic back disorders and recurrent back symptoms at baseline, as well as for work-related load and lifestyle factors. Other distress symptoms were not predictive of hospitalisation.

Tämän väitöskirjan tavoitteena oli tutkia sairaalahoitoon johtaneiden selkäsairauksien riskitekijöitä Suomessa. Ensiksi, sairaalahoitoon joutumista tarkasteltiin sosioekonomisen aseman, ammatin ja toimialan mukaan. Toiseksi, tutkittiin ennustavatko psykososiaaliset tekijät työssä, unihäiriöt, tupakointi ja ylipainoisuus sairaalahoitoon joutumista selkäsairauksien takia. Kaksi erilaista aineistoa oli käytössä: Ensimmäinen aineisto sisälsi koko työssä käyvän, 25 64-vuotiaan väestön tiedot sairaalahoidoista selkäsairauden takia vuodelta 1996. Toinen sisälsi laajan tutkimusaineiston kohortista, jonka sairaalahoitoon joutumista…

Subjects/Keywords: epidemiologia; epidemiologia

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Kaila-Kangas, L. (2006). Socioeconomic Status, Occupational Factors and Lifestyle as Predictors of Hospitalisation for Back Disorders. (Doctoral Dissertation). University of Helsinki. Retrieved from http://hdl.handle.net/10138/20338

Chicago Manual of Style (16^th Edition):

Kaila-Kangas, Leena. “Socioeconomic Status, Occupational Factors and Lifestyle as Predictors of Hospitalisation for Back Disorders.” 2006. Doctoral Dissertation, University of Helsinki. Accessed January 23, 2021. http://hdl.handle.net/10138/20338.

MLA Handbook (7^th Edition):

Kaila-Kangas, Leena. “Socioeconomic Status, Occupational Factors and Lifestyle as Predictors of Hospitalisation for Back Disorders.” 2006. Web. 23 Jan 2021.

Vancouver:

Kaila-Kangas L. Socioeconomic Status, Occupational Factors and Lifestyle as Predictors of Hospitalisation for Back Disorders. [Internet] [Doctoral dissertation]. University of Helsinki; 2006. [cited 2021 Jan 23]. Available from: http://hdl.handle.net/10138/20338.

Council of Science Editors:

Kaila-Kangas L. Socioeconomic Status, Occupational Factors and Lifestyle as Predictors of Hospitalisation for Back Disorders. [Doctoral Dissertation]. University of Helsinki; 2006. Available from: http://hdl.handle.net/10138/20338

University of Helsinki

13. Ojajärvi, Anneli. Occupational determinants of pancreatic cancer.

Degree: Department of Public Health; University of Helsinki, Faculty of Medicine, Department of Public Health; Finnish Institute of Occupational Health; Doctoral Programmes of Public Health, 2006, University of Helsinki

URL: http://hdl.handle.net/10138/20359

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Objective and background. Tobacco smoking, pancreatitis and diabetes mellitus are the only known causes of pancreatic cancer, leaving ample room for yet unidentified determinants. This… (more)

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Objective and background. Tobacco smoking, pancreatitis and diabetes mellitus are the only known causes of pancreatic cancer, leaving ample room for yet unidentified determinants. This is an empirical study on a Finnish data on occupational exposures and pancreatic cancer risk, and a non-Bayesian and a hierarchical Bayesian meta-analysis of data on occupational factors and pancreatic cancer. Methods. The case-control study analyzed 595 incident cases of pancreatic cancer and 1,622 controls of stomach, colon, and rectum cancer, diagnosed 1984-1987 and known to be dead by 1990 in Finland. The next-of-kin responded to a mail questionnaire on job and medical histories and lifestyles. Meta-analysis of occupational risk factors of pancreatic cancer started off with 1,903 identified studies. The analyses were based on different subsets of that database. Five epidemiologists examined the reports and extracted the pertinent data using a standardized extraction form that covered 20 study descriptors and the relevant relative risk estimates. Random effects meta-analyses were applied for 23 chemical agents. In addition, hierarchical Bayesian models for meta-analysis were applied to the occupational data of 27 job titles using job exposure matrix as a link matrix and estimating the relative risks of pancreatic cancer associated with nine occupational agents. Results. In the case-control study, logistic regressions revealed excess risks of pancreatic cancer associated with occupational exposures to ionizing radiation, nonchlorinated solvents, and pesticides. Chlorinated hydrocarbon solvents and related compounds, used mainly in metal degreasing and dry cleaning, are emerging as likely risk factors of pancreatic cancer in the non-Bayesian and the hierarchical Bayesian meta-analysis. Consistent excess risk was found for insecticides, and a high excess for nickel and nickel compounds in the random effects meta-analysis but not in the hierarchical Bayesian meta-analysis. Conclusions. In this study occupational exposure to chlorinated hydrocarbon solvents and related compounds and insecticides increase risk of pancreatic cancer. Hierarchical Bayesian meta-analysis is applicable when studies addressing the agent(s) under study are lacking or very few, but several studies address job titles with potential exposure to these agents. A job-exposure matrix or a formal expert assessment system is necessary in this situation.

Tausta ja tavoite. Haimasyövän syytekijöistä tiedetään varsin vähän. Tupakointi, haimatulehdus ja sokeritauti ovat sen ainoat toistaiseksi varmennetut syyt. Tämä on suomalaiseen aineistoon perustuva empiirinen tutkimus työperäisistä altisteista ja haimasyövän riskeistä sekä työperäisiin tekijöihin ja haimasyöpään perustuvan aineiston ei-bayesiläinen ja hierarkkinen bayesiläinen meta-analyysi. Menetelmät. Tapaus-verrokki tutkimuksen tulokset perustuvat 595:een haimasyöpään Suomessa ajanjaksona 1984-1987 sairastuneeseen ja vuoteen 1990 mennessä kuolleeseen tapaukseen sekä 1,622:een samana ajanjaksona todettuun…

Subjects/Keywords: epidemiologia; epidemiologia

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Ojajärvi, A. (2006). Occupational determinants of pancreatic cancer. (Doctoral Dissertation). University of Helsinki. Retrieved from http://hdl.handle.net/10138/20359

Chicago Manual of Style (16^th Edition):

Ojajärvi, Anneli. “Occupational determinants of pancreatic cancer.” 2006. Doctoral Dissertation, University of Helsinki. Accessed January 23, 2021. http://hdl.handle.net/10138/20359.

MLA Handbook (7^th Edition):

Ojajärvi, Anneli. “Occupational determinants of pancreatic cancer.” 2006. Web. 23 Jan 2021.

Vancouver:

Ojajärvi A. Occupational determinants of pancreatic cancer. [Internet] [Doctoral dissertation]. University of Helsinki; 2006. [cited 2021 Jan 23]. Available from: http://hdl.handle.net/10138/20359.

Council of Science Editors:

Ojajärvi A. Occupational determinants of pancreatic cancer. [Doctoral Dissertation]. University of Helsinki; 2006. Available from: http://hdl.handle.net/10138/20359

University of Helsinki

14. Haukka, Eija. Musculoskeletal disorders and psychosocial factors at work : Effects of a participatory ergonomics intervention in a cluster randomized controlled trial.

Degree: Hjelt Institute; Finnish Institute of Occupational Health, 2010, University of Helsinki

URL: http://hdl.handle.net/10138/20367

► This study examined the efficacy of a participatory ergonomics intervention in preventing musculoskeletal disorders (MSDs) and changing unsatisfactory psychosocial working conditions among municipal kitchen workers.… (more)

▼ This study examined the efficacy of a participatory ergonomics intervention in preventing musculoskeletal disorders (MSDs) and changing unsatisfactory psychosocial working conditions among municipal kitchen workers. The occurrence of multiple-site musculoskeletal pain (MSP) and associations between MSP and psychosocial factors at work over time were studied secondarily. A cluster randomized controlled trial was conducted during 2002-2005 in 119 municipal kitchens with 504 workers. The kitchens were randomized to an intervention (n = 59) and control (n = 60) group. The intervention lasted 11 to 14 months. The workers identified strenuous work tasks and sought solutions for decreasing physical and mental workload. The main outcomes were the occurrence of and trouble caused by musculoskeletal pain in seven anatomical sites, local musculoskeletal fatigue after work, and musculoskeletal sick leaves. Psychosocial factors at work (job control, skill discretion, co-worker relationships, supervisor support, mental strenuousness of work, hurry, job satisfaction) and mental stress were studied as intermediate outcomes of the intervention. Questionnaire data were collected at three months intervals during the intervention and the one-year post-intervention follow-up. Response rates varied between 92 % and 99 %. In total, 402 ergonomic changes were implemented. In the control group, 80 changes were spontaneously implemented within normal activity. The intervention did not reduce perceived physical workload and no systematic differences in any health outcomes were found between the intervention and control groups during the intervention or during the one-year follow-up. The results suggest that the intervention as studied in the present trial was not more effective in reducing perceived physical workload or preventing MSDs compared with no such intervention. Little previous evidence of the effectiveness of ergonomics interventions in preventing MSDs exists. The effects on psychosocial factors at work were adverse, especially in the two of the participating cities where re-organization of foodservices timed simultaneously with the intervention. If organizational reforms at workplace are expected to occur, the execution of other workplace interventions at the same time should be avoided. The co-occurrence of musculoskeletal pain at several sites is observed to be more common than pain at single anatomical sites. However, the risk factors of MSP are largely unknown. This study showed that at baseline, 73 % of the women reported pain in at least two, 36 % in four or more, and 10 % in six to seven sites. The seven pain symptoms occurred in over 80 different combinations. When co-occurrence of pain was studied in three larger anatomical areas (neck/low back, upper limbs, lower limbs), concurrent pain in all three areas was the most common combination (36 %). The 3-month prevalence of MSP (≥ 3 of seven sites) varied between 50 % and 61 % during the two-year follow-up period. Psychosocial factors at work and mental stress were…

Subjects/Keywords: kansanterveystiede, epidemiologia; kansanterveystiede, epidemiologia

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Haukka, E. (2010). Musculoskeletal disorders and psychosocial factors at work : Effects of a participatory ergonomics intervention in a cluster randomized controlled trial. (Doctoral Dissertation). University of Helsinki. Retrieved from http://hdl.handle.net/10138/20367

Chicago Manual of Style (16^th Edition):

Haukka, Eija. “Musculoskeletal disorders and psychosocial factors at work : Effects of a participatory ergonomics intervention in a cluster randomized controlled trial.” 2010. Doctoral Dissertation, University of Helsinki. Accessed January 23, 2021. http://hdl.handle.net/10138/20367.

MLA Handbook (7^th Edition):

Haukka, Eija. “Musculoskeletal disorders and psychosocial factors at work : Effects of a participatory ergonomics intervention in a cluster randomized controlled trial.” 2010. Web. 23 Jan 2021.

Vancouver:

Haukka E. Musculoskeletal disorders and psychosocial factors at work : Effects of a participatory ergonomics intervention in a cluster randomized controlled trial. [Internet] [Doctoral dissertation]. University of Helsinki; 2010. [cited 2021 Jan 23]. Available from: http://hdl.handle.net/10138/20367.

Council of Science Editors:

Haukka E. Musculoskeletal disorders and psychosocial factors at work : Effects of a participatory ergonomics intervention in a cluster randomized controlled trial. [Doctoral Dissertation]. University of Helsinki; 2010. Available from: http://hdl.handle.net/10138/20367

University of Helsinki

15. Heikkinen, Sanna. Lifestyle factors and breast cancer in Finland.

Degree: Clinicum, Department of Public Health; Finnish Cancer Registry, 2017, University of Helsinki

URL: http://hdl.handle.net/10138/176040

► Breast cancer is the most common cancer in women in Finland. It is often considered as a disease of affluent, Western societies with many known… (more)

▼ Breast cancer is the most common cancer in women in Finland. It is often considered as a disease of affluent, Western societies with many known risk factors such as late age at first birth, small number of children, and sedentary lifestyle, among others. In addition, there are more novel exposures that are popular in modern Western societies and carry suspected carcinogenic potential, including use of hormonal contraceptives and use of cosmetics, such as hair dyes. The aim of the thesis was to evaluate the roles of such lifestyle factors and to assess how they contribute to the spectrum of breast cancer risk factors. The thesis is composed of four sub studies; Study I estimating the association between use of hormonal contraceptives and breast cancer risk and Study II aiming at determining whether use of hair dyes independently increases risk of breast cancer. Study III estimated the proportion of women who had an opportunistic mammography before the age 50 years and assessed the roles of breast cancer family history and educational level in it. Study IV investigated the impact of major life events in breast cancer-specific mortality. Self-reported survey data was used as source of exposure information in all sub studies. Information on the outcomes of interest, namely breast cancer diagnosis and breast cancer-specific deaths were retrieved from the Finnish Cancer Registry. In Studies I and II, analyses by conditional logistic regression were conducted to estimate odds ratios (OR) and 95% confidence intervals (CI). In Study III, percentages of women reporting opportunistic mammography were calculated either directly of by Kaplan-Meier method. In Study IV, different Cox models were used to estimate breast cancer-specific mortality hazard ratios and 95 % CIs. Use of hormonal intrauterine device (HR IUD) increased the risk of breast cancer in post-menopausal women by 52% (OR 1.52, 95% CI: 1.14-2.02). Use of other hormonal contraception was by contrast associated with risk of breast cancer in younger women (OR 1.32, 95% CI: 1.08-1.61). An OR of 1.23 (95% CI: 1.11-1.36) was observed for women using hair dyes, relative to those who had never dyed their hair. Opportunistic mammography was also found to be very common, with more than 60% of responders reporting having had a mammography before screening age. Mammographies were also more common in women who had breast cancer family history and/or higher education. A large number of experienced negative life events was associated with 4% higher risk of breast cancer-specific mortality, some positive events accordingly lowering it. The prevalence of classical breast cancer risk factors, such as obesity and alcohol use have increased markedly over the past decades in Finland. Parity and total fertility are continuing to decline. These factors are more and more commonly complemented by risk effects produced by use of exogenous hormones and cosmetics such as hair dye. Considering increasing usage, further research on the effects of HR IUD use is needed with other populations…

Subjects/Keywords: kansanterveystiede/Epidemiologia; kansanterveystiede/Epidemiologia

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Heikkinen, S. (2017). Lifestyle factors and breast cancer in Finland. (Doctoral Dissertation). University of Helsinki. Retrieved from http://hdl.handle.net/10138/176040

Chicago Manual of Style (16^th Edition):

Heikkinen, Sanna. “Lifestyle factors and breast cancer in Finland.” 2017. Doctoral Dissertation, University of Helsinki. Accessed January 23, 2021. http://hdl.handle.net/10138/176040.

MLA Handbook (7^th Edition):

Heikkinen, Sanna. “Lifestyle factors and breast cancer in Finland.” 2017. Web. 23 Jan 2021.

Vancouver:

Heikkinen S. Lifestyle factors and breast cancer in Finland. [Internet] [Doctoral dissertation]. University of Helsinki; 2017. [cited 2021 Jan 23]. Available from: http://hdl.handle.net/10138/176040.

Council of Science Editors:

Heikkinen S. Lifestyle factors and breast cancer in Finland. [Doctoral Dissertation]. University of Helsinki; 2017. Available from: http://hdl.handle.net/10138/176040

16. Wollheim, Cláudia. Epidemiologia molecular de Escherichia coli e Klebsiella spp produtoras de beta-lactamase de espectro ampliado.

Degree: 2009, Universidade de Caxias do Sul

URL: https://repositorio.ucs.br/handle/11338/400

► As beta-lactamases de espectro ampliado (ESBL) representam um importante mecanismo de resistência aos beta-lactâmicos. Essas enzimas disseminaram-se entre membros da família Enterobacteriaceae que causam infecções… (more)

▼ As beta-lactamases de espectro ampliado (ESBL) representam um importante mecanismo de resistência aos beta-lactâmicos. Essas enzimas disseminaram-se entre membros da família Enterobacteriaceae que causam infecções relacionadas à assistência à saúde, especialmente as nosocomiais. Objetivos: (a) Determinar a prevalência de Escherichia coli e Klebsiella spp produtores de ESBL de origem hospitalar e comunitária; (b) Verificar a origem dos isolados (amostra clínica e unidade de internação); (c) Avaliar a acurácia dos testes fenotípicos de detecção de ESBL; (d) Determinar os perfis de sensibilidade aos antimicrobianos; (e) Determinar os genes de beta-lactamase; (f) Avaliar o modo de disseminação e; (g) Realizar experimentos de transferência de resistência. Material e métodos: Foram avaliados 1346 isolados (1162 E. coli, 180 K. pneumoniae e 4 K. oxytoca), de pacientes internados e ambulatoriais, entre abril de 2003 a maio de 2006, em Caxias do Sul. Um isolado/paciente foi incluído e a infecção hospitalar definida pelo CDC (Centers for Diseases Control and Prevention). Pelo método disco-difusão, conforme CLSI (Clinical and Laboratory Standards Institute) identificou-se os produtores de ESBL (triagem: aztreonam, cefotaxima, ceftazidima, ceftriaxona e cefpodoxima e confirmatório: cefpodoxima, ceftazidima, cefotaxima, com e sem ác. clavulânico). A cefepima foi incluída nos testes. Os isolados foram submetidos a testes de sensibilidade aos antimicrobianos, por disco-difusão, segundo a CLSI; ao método de PCR para detecção dos genes bla TEM, bla SHV, bla CTX-M e; à tipagem por PGFE. A cepa E. coli αDH, como receptora, foi usada na conjugação e os transconjugantes pesquisados para produção de ESBL e perfil de sensibilidade. Resultados: As prevalências de ESBL em nível hospitalar foram: K. pneumoniae (43,7%) e E. coli (6,7%) e a comunidade, respectivamente, de 2,6% e 0,4%. As vias aéreas (escarro, aspirado traqueal, lavado broncoalveolar) , sangue e urina, e as UTIs e Clínica-Cirúrgicas foram as amostras clínicas e unidades de internação com os maiores percentuais de isolados produtores de ESBL. Independente da bactéria analisada, a ceftazidima foi o substrato com o pior desempenho nos testes. Já a cefpodoxima, a cefotaxima, a ceftriaxona e o aztreonam apresentaram sensibilidade de 100% e especificidade >94,0% para isolados de Klebsiella spp. Para E. coli a cefpodoxima foi o melhor substrato (sensibilidade de 100,0% e especificidade de 75,0%). A cepefima apresentou excelente desempenho. Os isolados de Klebsiella spp produtores de ESBL apresentaram taxas de resistência superiores àqueles apresentados pelos isolados não produtores de ESBL, para vários antimicrobianos beta-lactâmicos e não beta-lactâmicos. Independente da produção de ESBL esses isolados foram sensíveis aos carbapenêmicos e tigeciglina. Foram detectados em E. coli e Klebsiella spp com fenóitpo ESBL os genes de beta-lactamase blaTEM (89,0%), blaCTX-M (75,6%) e blaSHV (35,4%). Foram identificados 22 padrões de PFGE, sendo 11 com mais de um isolado. Esses padrões… Advisors/Committee Members: Costa, Sergio Olavo Pinto da.

Subjects/Keywords: EPIDEMIOLOGIA; Microbiologia médica; Epidemiologia molecular

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Wollheim, C. (2009). Epidemiologia molecular de Escherichia coli e Klebsiella spp produtoras de beta-lactamase de espectro ampliado. (Doctoral Dissertation). Universidade de Caxias do Sul. Retrieved from https://repositorio.ucs.br/handle/11338/400

Chicago Manual of Style (16^th Edition):

Wollheim, Cláudia. “Epidemiologia molecular de Escherichia coli e Klebsiella spp produtoras de beta-lactamase de espectro ampliado.” 2009. Doctoral Dissertation, Universidade de Caxias do Sul. Accessed January 23, 2021. https://repositorio.ucs.br/handle/11338/400.

MLA Handbook (7^th Edition):

Wollheim, Cláudia. “Epidemiologia molecular de Escherichia coli e Klebsiella spp produtoras de beta-lactamase de espectro ampliado.” 2009. Web. 23 Jan 2021.

Vancouver:

Wollheim C. Epidemiologia molecular de Escherichia coli e Klebsiella spp produtoras de beta-lactamase de espectro ampliado. [Internet] [Doctoral dissertation]. Universidade de Caxias do Sul; 2009. [cited 2021 Jan 23]. Available from: https://repositorio.ucs.br/handle/11338/400.

Council of Science Editors:

Wollheim C. Epidemiologia molecular de Escherichia coli e Klebsiella spp produtoras de beta-lactamase de espectro ampliado. [Doctoral Dissertation]. Universidade de Caxias do Sul; 2009. Available from: https://repositorio.ucs.br/handle/11338/400

Universidade de Brasília

17. Camila Cristina Bastos Silva Raposo Ramos. Malária vivax na pré-amazônia maranhense : aspectos epidemiológicos e características clínicas.

Degree: 2006, Universidade de Brasília

URL: http://bdtd.bce.unb.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=1433

► No trabalho de campo, foram estudados 140 pacientes, sendo 93% do gênero masculino. A idade dos pacientes variou de 12 meses a 70 anos de… (more)

▼ No trabalho de campo, foram estudados 140 pacientes, sendo 93% do gênero masculino. A idade dos pacientes variou de 12 meses a 70 anos de idade, com predomínio da idade adulta (73,2%). Apenas 7,8% dos casos foram importados de outros estados ou países. A maioria dos pacientes (69%) estava tendo malaria por mais de uma vez. A média de tempo decorrido entre o início dos sintomas e a realização do diagnóstico foi de três dias, tendo sido iniciado o tratamento com cloroquina e primaquina no mesmo dia do diagnóstico em todos os pacientes. A parasitemia em 36,9% dos casos variou entre 500 a 10000 parasitas/ mm3 (++V). Quanto ao quadro clínico, predominou a tríade clássica: febre (100%), calafrios (97,9%) e sudorese (86,4%). Foram observados também, manifestações de gravidade como: sonolência (1,4%), confusão mental (0,7%), convulsão (1,4%), perda de consciência (1,4%), hemorragia (6,4%) e dispnéia (2,9%). Entre os pacientes internados, foram incluídos 12 pacientes primoinfectados com manifestações clínicas e/ou laboratoriais de gravidade.. O tempo de diagnóstico variou de 6 a 29 dias, porém apenas um paciente apresentou parasitemia acima de 10.000 parasitas/mm3. Com relação à sintomatologia, 10 pacientes apresentaram icterícia, 5 confusão mental, 5 perda de consciência, 2 dispnéia, 1 hemorragia conjuntival e 1 hematúria e hemorragia digestiva alta. A complicação laboratorial mais frequentemente encontrada foi a trombocitopenia presente em 8 pacientes. Hemoglobina inferior a 10g% foi verificada em 4 pacientes. Insuficiência renal foi diagnosticada em 5 pacientes, dos quais apenas 1 necessitou de tratamento dialítico. Todos os pacientes evoluíram de forma favorável após instituição do tratamento específico com cloroquina e primaquina. A malária por P. vivax, embora mais raramente que na infecção pelo P. falciparum, pode evoluir de forma grave, mesmo em áreas endêmicas, onde a maioria das pessoas já tiveram vários episódios maláricos, e portanto, apresenta certo grau de imunidade. Está geralmente associada a retardo no diagnóstico e tratamento, porém costuma responder de forma satisfatória à instituição da terapêutica. Advisors/Committee Members: João Barberino Santos.

Subjects/Keywords: malária; epidemiologia; gravidade clínica; EPIDEMIOLOGIA

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Ramos, C. C. B. S. R. (2006). Malária vivax na pré-amazônia maranhense : aspectos epidemiológicos e características clínicas. (Thesis). Universidade de Brasília. Retrieved from http://bdtd.bce.unb.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=1433

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Ramos, Camila Cristina Bastos Silva Raposo. “Malária vivax na pré-amazônia maranhense : aspectos epidemiológicos e características clínicas.” 2006. Thesis, Universidade de Brasília. Accessed January 23, 2021. http://bdtd.bce.unb.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=1433.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Ramos, Camila Cristina Bastos Silva Raposo. “Malária vivax na pré-amazônia maranhense : aspectos epidemiológicos e características clínicas.” 2006. Web. 23 Jan 2021.

Vancouver:

Ramos CCBSR. Malária vivax na pré-amazônia maranhense : aspectos epidemiológicos e características clínicas. [Internet] [Thesis]. Universidade de Brasília; 2006. [cited 2021 Jan 23]. Available from: http://bdtd.bce.unb.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=1433.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Ramos CCBSR. Malária vivax na pré-amazônia maranhense : aspectos epidemiológicos e características clínicas. [Thesis]. Universidade de Brasília; 2006. Available from: http://bdtd.bce.unb.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=1433

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

18. Freire, Ernane Rodrigues. Estudo das vari?veis de s?ntese e o efeito nas propriedades eletroqu?micas da polianilina.

Degree: 2019, Universidade Federal do Amazonas

URL: https://tede.ufam.edu.br/handle/tede/7678

►

Existe uma busca crescente por energia limpa e renov?vel, que deve ser acompanhada pelo desenvolvimento de dispositivos eficientes de armazenamento de energia. Um dispositivo de… (more)

▼

Existe uma busca crescente por energia limpa e renov?vel, que deve ser acompanhada pelo desenvolvimento de dispositivos eficientes de armazenamento de energia. Um dispositivo de grande interesse ? o capacitor eletroqu?mico, especificamente, os pseudocapacitores que utilizam uma variedade de materiais como PANI ou ?xidos met?licos como eletrodos. A PANI ? um pol?mero intrinsecamente condutor que pode ser sintetizada pela rota qu?mica ou eletroqu?mica. A primeira ? a mais adequada para se obter um pol?mero com alto peso molecular, o que ? primordial para a aplica??o sugerida. Nesse intuito, este trabalho apresenta os resultados de estudos das varia??es das concentra??es do agente dopante, agente oxidante e temperatura de s?ntese qu?mica da PANI para futuras aplica??es eletroqu?micas. Os materiais obtidos foram caracterizados por MEV, espectroscopia de UV-vis, FTIR, voltametria c?clica (-0,2 a 1,2 V), carga/descarga galvanost?tica e imped?ncia eletroqu?mica. As caracteriza??es estruturais e ?pticas comprovaram a obten??o do pol?mero no estado condutor para todas as condi??es de s?nteses. As an?lises morfol?gicas revelaram a diminui??o do tamanho de gr?nulos conforme o aumento da concentra??o de ?cido sulf?rico (agente dopante). Enquanto que a segunda vari?vel de s?ntese mostrou tamanhos menores de gr?nulos na concentra??o de 2,5 mol.L-1 de PSA (agente oxidante). J? a varia??o de temperatura apresentou gr?nulos na superf?cie de nofibras nas temperaturas de s?ntese de -5 e 0?C, em contrapartida, ocorreu a forma??o de estruturas na forma de placas em 5?C. Os estudos por voltametria c?clica mostraram diferentes respostas para cada condi??o de s?ntese, tendo potenciais dos estados redox da PANI de acordo com a literatura e aus?ncia de picos redox em outras condi??es, em sua maioria, observou-se processos at? a velocidade de varredura de 25 mV.s-1. A capacit?ncia calculada por voltametria atingiu os maiores valores em 224, 271, 328,2 F.g-1, respectivamente, 0,5 mol.L-1 de ?cido sulf?rico, 3,5 mol.L-1 de PSA e 0?C, a 10 mV.s-1. Os maiores valores de capacit?ncia calculadas por carga/descarga foram para as mesmas condi??es. E pela imped?ncia, todas as amostras mostraram a presen?a de semic?rculo com baixa resist?ncia a transporte de carga e bons efeitos capacitivos.

The growing search for clean and renewable energy should be accompanied by the development of efficient energy storage devices. A device of great interest is the electrochemical capacitor, specifically the pseudocapacitors that use a variety of materials such as PANI or metal oxides as electrodes. PANI is an intrinsically conductive polymer that can be synthesized by the chemical or electrochemical route. The first is the most suitable to obtain a PANI with high molecular weight, which is paramount for suggested application. In this regard, this study presents the results of studies of variations in the concentrations of the dopant agent, oxidant agent and chemical synthesis temperature of PANI for possible application in supercapacitors. The materials obtained…

Advisors/Committee Members: Pocrifka, Leandro Aparecido, http://lattes.cnpq.br/6236326108324745, Rios, Emerson da Costa, http://lattes.cnpq.br/8791195940411823, Frota, Consuelo Alves da.

Subjects/Keywords: Pol?meros condutores; Capacitadores; ENGENHARIAS: ENGENHARIA DE MATERIAIS E METAL?RGICA; S?ntese qu?mica; Polianilina; Propriedades eletroqu?micas

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Freire, E. R. (2019). Estudo das vari?veis de s?ntese e o efeito nas propriedades eletroqu?micas da polianilina. (Masters Thesis). Universidade Federal do Amazonas. Retrieved from https://tede.ufam.edu.br/handle/tede/7678

Chicago Manual of Style (16^th Edition):

Freire, Ernane Rodrigues. “Estudo das vari?veis de s?ntese e o efeito nas propriedades eletroqu?micas da polianilina.” 2019. Masters Thesis, Universidade Federal do Amazonas. Accessed January 23, 2021. https://tede.ufam.edu.br/handle/tede/7678.

MLA Handbook (7^th Edition):

Freire, Ernane Rodrigues. “Estudo das vari?veis de s?ntese e o efeito nas propriedades eletroqu?micas da polianilina.” 2019. Web. 23 Jan 2021.

Vancouver:

Freire ER. Estudo das vari?veis de s?ntese e o efeito nas propriedades eletroqu?micas da polianilina. [Internet] [Masters thesis]. Universidade Federal do Amazonas; 2019. [cited 2021 Jan 23]. Available from: https://tede.ufam.edu.br/handle/tede/7678.

Council of Science Editors:

Freire ER. Estudo das vari?veis de s?ntese e o efeito nas propriedades eletroqu?micas da polianilina. [Masters Thesis]. Universidade Federal do Amazonas; 2019. Available from: https://tede.ufam.edu.br/handle/tede/7678

Universidade do Porto

19. Figueiredo, Daniela Fernandes de Carvalho. Pressão Arterial:Implicação do número de medições na estimativa da prevalência da hipertensão.

Degree: 2011, Universidade do Porto

URL: http://www.rcaap.pt/detail.jsp?id=oai:repositorio-aberto.up.pt:10216/22102

►

Mestrado em Epidemiologia

Master Degree Course in Epidemiology

PRESSÃO ARTERIAL: IMPLICAÇÃO DO NÚMERO DE MEDIÇÕES NA ESTIMATIVA DA PREVALÊNCIA DE HIPERTENSÃO Daniela Figueiredo Porto 2007… (more)

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Mestrado em Epidemiologia

Master Degree Course in Epidemiology

PRESSÃO ARTERIAL: IMPLICAÇÃO DO NÚMERO DE MEDIÇÕES NA ESTIMATIVA DA PREVALÊNCIA DE HIPERTENSÃO Daniela Figueiredo Porto 2007 Dissertação da candidatura ao grau de Mestre em Epidemiologia apresentada à Faculdade de Medicina da Universidade do Porto O diagnóstico de hipertensão arterial deve basear-se em múltiplas medições de pressão arterial (PA), recolhidas em, pelo menos, duas visitas diferentes. Pretendemos avaliar e quantificar o impacto causado pela utilização de diferentes critérios para a definição de hipertensão arterial, tendo em conta o número de observações em que se baseiam, na estimativa de prevalência de hipertensão arterial e comparar a associação entre hipertensão arterial, definida pelos diferentes critérios, e duas variáveis reconhecidamente associadas à hipertensão arterial: o índice de massa corporal e a hipertrofia ventricular esquerda. Os dados da amostra foram recolhidos num estudo transversal com 739 participantes, com idade 45 anos, seleccionados de forma aleatória de uma população Portuguesa, não institucionalizada, de Janeiro de 2001 a Dezembro de 2003. As principais medidas a estudar eram a prevalência de hipertensão arterial (PA sistólica 140 mmHg e/ou PA diastólica 90 mmHg ou medicação com fármacos antihipertensores) baseada nas medições de PA numa primeira avaliação, baseada nas medições de PA numa segunda avaliação e cumprindo os mesmos critérios nas duas avaliações, separadas por um período mediano de 14 dias. Estudámos a associação desses três critérios diferentes com o índice de massa corporal e com a hipertrofia ventricular esquerda. A estimativa de prevalência de hipertensão arterial era 63.4% (95%CI:59.8-66.9) usando as medições de PA da primeira avaliação (HTA1) e era 60.2% (95%CI:56.6-63.8) usando as medições de PA da segunda avaliação (HTA2). Usando o mesmo critério nas duas avaliações a estimativa de prevalência de hipertensão arterial (HTAFinal) era 56.3% (95%CI: 52.7-60.0), p(McNemar)<0.001, entre HTA1 e HTAFinal e entre HTA2 e HTAFinal. Ambas as estimativas tinham uma associação forte e independente com o índice de massa corporal (Odds Ratio=2,71 para o índice de massa corporal 30 kg/m2 com HTAFinal) e com a hipertrofia ventricular esquerda (Odds ratio=3,21 para a HTAFinal com a hipertrofia ventricular esquerda). Em muitos indivíduos considerados hipertensos numa avaliação única, a hipertensão não se confirmou na segunda avaliação sobrestimando a prevalência de hipertensão arterial, significativamente, em 14,6%. No entanto, uma medição de pressão arterial anormalmente alta, num indivíduo com mais de 45 anos, está associada com a hipertrofia ventricular esquerda.

The diagnosis of arterial hypertension should be based on multiple blood pressure (BP) measurements, taken on at least two separate occasions. We aimed to assess the impact of considering different criteria for arterial hypertension definition, based on the numbers of visits for BP measurements, on the estimate of arterial hypertension…

Subjects/Keywords: Epidemiologia; Porto

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Figueiredo, D. F. d. C. (2011). Pressão Arterial:Implicação do número de medições na estimativa da prevalência da hipertensão. (Thesis). Universidade do Porto. Retrieved from http://www.rcaap.pt/detail.jsp?id=oai:repositorio-aberto.up.pt:10216/22102

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Figueiredo, Daniela Fernandes de Carvalho. “Pressão Arterial:Implicação do número de medições na estimativa da prevalência da hipertensão.” 2011. Thesis, Universidade do Porto. Accessed January 23, 2021. http://www.rcaap.pt/detail.jsp?id=oai:repositorio-aberto.up.pt:10216/22102.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Figueiredo, Daniela Fernandes de Carvalho. “Pressão Arterial:Implicação do número de medições na estimativa da prevalência da hipertensão.” 2011. Web. 23 Jan 2021.

Vancouver:

Figueiredo DFdC. Pressão Arterial:Implicação do número de medições na estimativa da prevalência da hipertensão. [Internet] [Thesis]. Universidade do Porto; 2011. [cited 2021 Jan 23]. Available from: http://www.rcaap.pt/detail.jsp?id=oai:repositorio-aberto.up.pt:10216/22102.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Figueiredo DFdC. Pressão Arterial:Implicação do número de medições na estimativa da prevalência da hipertensão. [Thesis]. Universidade do Porto; 2011. Available from: http://www.rcaap.pt/detail.jsp?id=oai:repositorio-aberto.up.pt:10216/22102

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universidade do Porto

20. Guedes, Sandra Maria Rosa. Prevalence of drug use in a portuguese urban population:an emphasis on diabetes.

Degree: 2011, Universidade do Porto

URL: http://www.rcaap.pt/detail.jsp?id=oai:repositorio-aberto.up.pt:10216/22075

►

Mestrado em Epidemiologia

Master Degree Course in Epidemiology

O consumo de fármacos está a aumentar cada vez mais em todas as sociedades. Este facto tem… (more)

▼

Mestrado em Epidemiologia

Master Degree Course in Epidemiology

O consumo de fármacos está a aumentar cada vez mais em todas as sociedades. Este facto tem implicações importantes quer a nível individual quer a nível das populações, bem como para uma eficiente gestão de recursos de saúde, nomeadamente se tivermos em atenção que muitas das vezes a utilização de fármacos é desnecessária, inadequada ou irracional. Os estudos descritivos são necessários para perceber de que forma os fármacos estão a ser utilizados, por quem e em que circunstâncias está a ocorrer a sua utilização. Sabe-se que existem discrepâncias entre o uso de fármacos na prática clínica usual e as recomendações nacionais ou internacionais. Conhecer e compreender o contexto da utilização de fármacos é essencial para o desenvolvimento de intervenções e avaliação do seu impacto.

We are assisting to an increasing medicines use all over our societies. This has major implications for both individuals and populations and for efficient health resources utilization, as much of that use may be unnecessary, inappropriate or irrational. Descriptive studies are needed to understand which drugs are being used and by whom, when and how they are used. Discrepancies between actual use and national or international prescription guidelines exist. The knowledge and the understanding of the context of drug use situation are crucial to develop and evaluate the impact of further interventions This study aims to identify factors that contribute to the knowledge of how medicines are being used by individuals, with a specially emphasis on diabetes disorder therapeutic management. These should be accomplished by means of the following specific objectives: - To determine the prevalence of drug use in a Portuguese urban population, identify its determinants and the main therapeutic groups involved Manuscript 1 - To determine de prevalence of reported diabetes and self-reported drug use, and to compare it with existent guidelines Manuscript 2 43

Subjects/Keywords: Epidemiologia; Porto

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Guedes, S. M. R. (2011). Prevalence of drug use in a portuguese urban population:an emphasis on diabetes. (Thesis). Universidade do Porto. Retrieved from http://www.rcaap.pt/detail.jsp?id=oai:repositorio-aberto.up.pt:10216/22075

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Guedes, Sandra Maria Rosa. “Prevalence of drug use in a portuguese urban population:an emphasis on diabetes.” 2011. Thesis, Universidade do Porto. Accessed January 23, 2021. http://www.rcaap.pt/detail.jsp?id=oai:repositorio-aberto.up.pt:10216/22075.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Guedes, Sandra Maria Rosa. “Prevalence of drug use in a portuguese urban population:an emphasis on diabetes.” 2011. Web. 23 Jan 2021.

Vancouver:

Guedes SMR. Prevalence of drug use in a portuguese urban population:an emphasis on diabetes. [Internet] [Thesis]. Universidade do Porto; 2011. [cited 2021 Jan 23]. Available from: http://www.rcaap.pt/detail.jsp?id=oai:repositorio-aberto.up.pt:10216/22075.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Guedes SMR. Prevalence of drug use in a portuguese urban population:an emphasis on diabetes. [Thesis]. Universidade do Porto; 2011. Available from: http://www.rcaap.pt/detail.jsp?id=oai:repositorio-aberto.up.pt:10216/22075

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universidade do Rio Grande do Sul

21. Manzolli, Patricia Portantiolo. Violência e sintomas psiquiátricos em gestantes de serviços públicos de saúde no sul do Brasil : prevalência e fatores associados.

Degree: 2007, Universidade do Rio Grande do Sul

URL: http://hdl.handle.net/10183/11498

Resumo não disponível. Advisors/Committee Members: Nunes, Maria Angelica Antunes.

Subjects/Keywords: Epidemiologia

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Manzolli, P. P. (2007). Violência e sintomas psiquiátricos em gestantes de serviços públicos de saúde no sul do Brasil : prevalência e fatores associados. (Thesis). Universidade do Rio Grande do Sul. Retrieved from http://hdl.handle.net/10183/11498

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Manzolli, Patricia Portantiolo. “Violência e sintomas psiquiátricos em gestantes de serviços públicos de saúde no sul do Brasil : prevalência e fatores associados.” 2007. Thesis, Universidade do Rio Grande do Sul. Accessed January 23, 2021. http://hdl.handle.net/10183/11498.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Manzolli, Patricia Portantiolo. “Violência e sintomas psiquiátricos em gestantes de serviços públicos de saúde no sul do Brasil : prevalência e fatores associados.” 2007. Web. 23 Jan 2021.

Vancouver:

Manzolli PP. Violência e sintomas psiquiátricos em gestantes de serviços públicos de saúde no sul do Brasil : prevalência e fatores associados. [Internet] [Thesis]. Universidade do Rio Grande do Sul; 2007. [cited 2021 Jan 23]. Available from: http://hdl.handle.net/10183/11498.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Manzolli PP. Violência e sintomas psiquiátricos em gestantes de serviços públicos de saúde no sul do Brasil : prevalência e fatores associados. [Thesis]. Universidade do Rio Grande do Sul; 2007. Available from: http://hdl.handle.net/10183/11498

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

22. Saraiva, Sofia Teixeira. Epidemiologia e diagnóstico de dermatofitose em humanos e animais: uma abordagem “One Health”.

Degree: 2017, RCAAP

URL: http://www.rcaap.pt/detail.jsp?id=oai:http://repositorio.utad.pt/:10348/7982

►

Dissertação de Mestrado em Biotecnologia para as Ciências da Saúde

As doenças fúngicas dermatológicas como as dermatofitoses ou tinha, são das infeções mais frequentes a… (more)

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Dissertação de Mestrado em Biotecnologia para as Ciências da Saúde

As doenças fúngicas dermatológicas como as dermatofitoses ou tinha, são das infeções mais frequentes a nível mundial (Shimamura et al., 2012; Hube et. al, 2015) afetando também a maioria dos animais de companhia, ruminantes e vida selvagem (Chermette et al., 2008). Desta forma apresentam uma preocupação a nível da saúde pública e veterinária. A finalidade deste trabalho foi efetuar um estudo epidemiológico de dermatófitos isolados em animais selvagens, animais domésticos e em humanos. Esta parte do trabalho foi realizada recorrendo a métodos microbiológicos. A partir desses resultados foi calculada a prevalência de dermatófitos em diferentes espécies. Com uma prevalência total de 7,9% de isolados de dermatófitos obtidos, a coexistência destes fungos com animais selvagens foi comprovada para raposas e sacarrabos. Nos animais domésticos a prevalência de isolamento foi de 9,3% correspondendo a amostras de animais assintomáticos. Um teste à sensibilidade e especificidade do DTM demonstrou a fragilidade deste método e os erros que podem vir associados. Um estudo de caso em humanos demonstrou a presença do fungo Aspergillus num quadro clínico representativo de dermatofitose. Recorrendo a técnicas moleculares pretendeu efetuar-se uma otimização das mesmas de forma a obter um método complementar de diagnóstico mais fiável e rápido usando “primers” específicos para a identificação de dermatófitos. A identificação de dermatófitos através de “primers” específicos não obteve resultados satisfatórios e por isso foi estudada a diversidade genética das estirpes de dermatófitos isoladas através da análise das mesmas com recurso a marcadores moleculares, mais especificamente, os ISSRs. Mostra-se então de extrema importância inferir acerca do papel dos animais estudados na infeção de dermatofitoses e realizar mais estudos que permitam o estudo epidemiológico e molecular dos dermatófitos de forma a permitir uma melhor identificação, levando ao melhoramento das técnicas de diagnóstico.

The dermatologic diseases caused by moulds, like the dermatophytosis, are the most common infections at a world level (Shimamura et al., 2012; Hube et. al, 2015). They also affect the majority of the pets, ruminants and wild life (Chermette et al., 2008). This way they represent a concern on a level of public and veterinarian health. The finality of this study was to do an epidemiologic study of isolated dermatophytes in wild animals, domestics and in humans. This part was realized using microbiologic techniques. The prevalence of the dermatophytes in different species was calculated through this results. In regards to the prevalence of 7,9% of dermatophytes isolates, the coexistence of this moulds with wild animals was verified to Vulpes vulpes and Herpestes ichneumon. In the domestic animals the prevalence was 9,3% corresponding to asymptomatic animals. A test to the sensibility and specificity revealed the fragility of this method and the errors associated. A case report of humans…

Advisors/Committee Members: Coelho, Ana Cláudia Correia, Matos, Maria Manuela do Outeiro Correia de.

Subjects/Keywords: Dermatófitos; Epidemiologia

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Saraiva, S. T. (2017). Epidemiologia e diagnóstico de dermatofitose em humanos e animais: uma abordagem “One Health”. (Thesis). RCAAP. Retrieved from http://www.rcaap.pt/detail.jsp?id=oai:http://repositorio.utad.pt/:10348/7982

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Saraiva, Sofia Teixeira. “Epidemiologia e diagnóstico de dermatofitose em humanos e animais: uma abordagem “One Health”.” 2017. Thesis, RCAAP. Accessed January 23, 2021. http://www.rcaap.pt/detail.jsp?id=oai:http://repositorio.utad.pt/:10348/7982.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Saraiva, Sofia Teixeira. “Epidemiologia e diagnóstico de dermatofitose em humanos e animais: uma abordagem “One Health”.” 2017. Web. 23 Jan 2021.

Vancouver:

Saraiva ST. Epidemiologia e diagnóstico de dermatofitose em humanos e animais: uma abordagem “One Health”. [Internet] [Thesis]. RCAAP; 2017. [cited 2021 Jan 23]. Available from: http://www.rcaap.pt/detail.jsp?id=oai:http://repositorio.utad.pt/:10348/7982.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Saraiva ST. Epidemiologia e diagnóstico de dermatofitose em humanos e animais: uma abordagem “One Health”. [Thesis]. RCAAP; 2017. Available from: http://www.rcaap.pt/detail.jsp?id=oai:http://repositorio.utad.pt/:10348/7982

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universidade Estadual de Campinas

23. Siqueira, Lhys Marina Girard. Cavernomas cerebrais : estudos das manifestações clinicas e avaliação do tratamento cirurgico.

Degree: 2000, Universidade Estadual de Campinas

URL: http://repositorio.unicamp.br/jspui/handle/REPOSIP/310071

► Abstract: Cavernous angiomas are congenital vascular malformations, characterized by enlarged capillary cavities without intervening with arteries, veins or brain parenchyma. The objective for the present… (more)

▼ Abstract: Cavernous angiomas are congenital vascular malformations, characterized by enlarged capillary cavities without intervening with arteries, veins or brain parenchyma. The objective for the present study is to analyze a series of 84 patients with this pathology follow at the Centre Hospitalier Pitie-Salpetriere in Paris in the period of 1953 to 1995, for a diagnostic and neuroradiological study and the propositions of treatment. Evaluating this series and comparing with data from the biography, we study the natural history of the disease and the results, looking for the best treatment for the different types of presentations. Using retrospective analysis as method, added with longitudinal retrospective ambulatorial study, it was possible for us to classify the patients by clinical presentation and verify the results of the different treatments. The method of choice for diagnosis was MRI. In this series 39 patients had seizures, 15 had cerebral or subarachnoidea hemorrhage and 28 previously had a hemorrhage with a pseudo tumoral evolution; they have been classified as hemorrhagics. In this statistical comparison the results were similar to those already published; however, the patients have experienced rebleeding far sooner than the documented time in 28% of the cases. The total of rebleedings was 38% with 28 cases. Even in the absence of elements of malignity confirmed by histopathology, we took in consideration the evolutivity of the pathology, associated with the results, to show the tendency to the choice precoce surgical treatment, curative, especially in accessible brain areas. Consequently, the evaluation of each patient will be very important in order to select the most effective treatment Advisors/Committee Members: UNIVERSIDADE ESTADUAL DE CAMPINAS (CRUESP), Facure, José Jorge, 1942- (advisor), Universidade Estadual de Campinas. Faculdade de Ciências Médicas (institution), Programa de Pós-Graduação em Ciências Médicas (nameofprogram), Ribas, Guilherme Carvalhal (committee member), Bonatelli, Antonio de Padua Furquim (committee member), Dantas Filho, Venâncio Pereira (committee member), Honorato, Donizeti César (committee member).

Subjects/Keywords: Epidemiologia

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Siqueira, L. M. G. (2000). Cavernomas cerebrais : estudos das manifestações clinicas e avaliação do tratamento cirurgico. (Thesis). Universidade Estadual de Campinas. Retrieved from http://repositorio.unicamp.br/jspui/handle/REPOSIP/310071

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Siqueira, Lhys Marina Girard. “Cavernomas cerebrais : estudos das manifestações clinicas e avaliação do tratamento cirurgico.” 2000. Thesis, Universidade Estadual de Campinas. Accessed January 23, 2021. http://repositorio.unicamp.br/jspui/handle/REPOSIP/310071.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Siqueira, Lhys Marina Girard. “Cavernomas cerebrais : estudos das manifestações clinicas e avaliação do tratamento cirurgico.” 2000. Web. 23 Jan 2021.

Vancouver:

Siqueira LMG. Cavernomas cerebrais : estudos das manifestações clinicas e avaliação do tratamento cirurgico. [Internet] [Thesis]. Universidade Estadual de Campinas; 2000. [cited 2021 Jan 23]. Available from: http://repositorio.unicamp.br/jspui/handle/REPOSIP/310071.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Siqueira LMG. Cavernomas cerebrais : estudos das manifestações clinicas e avaliação do tratamento cirurgico. [Thesis]. Universidade Estadual de Campinas; 2000. Available from: http://repositorio.unicamp.br/jspui/handle/REPOSIP/310071

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Technical University of Lisbon

24. Ferreira, João Diogo Bernardo Bragança. Presence of Cryptosporidium baileyi in different Red Grouse (Lagopus lagopus scoticus) moors and its relation with agents of other avian diseases.

Degree: 2015, Technical University of Lisbon

URL: http://www.rcaap.pt/detail.jsp?id=oai:www.repository.utl.pt:10400.5/9282

►

Dissertação de Mestrado Integrado em Medicina Veterinária

ABSTRACT - Respiratory cryptosporidiosis was first diagnosed in wild Red Grouse (Lagopus lagopus scoticus) in autumn 2010 from… (more)

▼

Dissertação de Mestrado Integrado em Medicina Veterinária

ABSTRACT - Respiratory cryptosporidiosis was first diagnosed in wild Red Grouse (Lagopus lagopus scoticus) in autumn 2010 from a grouse moor in the North Pennine Dales in the UK. Three years after, 48% of grouse moors in Northern England had Red Grouse with severe lesions. The present survey was projected by St David’s Game Bird Services, it was performed with the purpose of gathering information regarding Cryptosporidium baileyi, concomitant parasites (Trichostrongylus tenuis and Eimeria spp.) and other different avian disease agents (Mycoplasma synoviae, Mycoplasma gallisepticum, Ornithobacterium rhinotracheale, Infectious Bronchitis Virus and Avian Rhinotracheitis Virus) that may also be implicated in cryptosporidiosis outbreaks. Age, gender and weight were additionally recorded to better comprehend the distribution of this disease through different groups (age and gender) and its relation with weight. Different agents were evaluated by using: head histopathology and corneal impression smear (stained by the modified Ziehl Neelsen technique) for C. baileyi and modified McMaster technique for counting Eimeria spp. oocysts and T. tenuis eggs per gram of faeces. Pooled samples (ocular swabs) were used to assess, through PCR technique, the presence of other different avian disease agents. Regarding statistical analyses, two-sample Wilcoxon test, linear regression analysis and Fisher’s exact test were used to test statistical significance differences among variables. Positive results for C. baileyi were composed by 18.42% (7 out of 38) adults and 30.77% (16 out of 36) young birds. Statistically significant differences between age and gender groups were not found (p>0.05; OR=0.51). 70.00% (21 out of 30) of birds with clinical signs were positive for C. baileyi, compared with 3.33% (2 out of 60) that were positive without clinical signs, which differences were statistically significant (p<0.001; OR= 0.02). The median weight of positive animals for C. baileyi was 604g and 629g for negative birds, however no statistical significance was found between weight and the presence of C. baileyi (W=601; p>0.05). No statistically significant relationships were found between the presence of C. baileyi and Eimeria spp. or T. tenuis intensities (p>0.05). A statistically significant relation was found between grouse weight and Eimeria spp. intensity (p<0.01). Additionaly, three positive results (pools composed by 5 birds) were obtained for Infectious Bronchitis Virus, two of them from birds with evident clinical signs and one from aparently healthy birds. This study did not find any statistically significant relation between the presence of C. baileyi and other parasites, viruses or bacteria. However a worthy description of those agents and how they can be implicated in the Red Grouse life span was made, also aiming to raise the awareness and potentially encouraging new perspectives on cryptosporidiosis prevention and control.

RESUMO - Presença de Cryptosporidium baileyi em…

Advisors/Committee Members: Carvalho, Luís Manuel Madeira de, Beynon, Alan.

Subjects/Keywords: Red Grouse; Cryptosporidium baileyi; Bulgy eye; Intestinal parasites; Infectious agents; GB, Scotland; Lagópode-escocês; Conjuntivite; Criptosporidiose respiratória; Parasitas; GB, Escócia

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Ferreira, J. D. B. B. (2015). Presence of Cryptosporidium baileyi in different Red Grouse (Lagopus lagopus scoticus) moors and its relation with agents of other avian diseases. (Thesis). Technical University of Lisbon. Retrieved from http://www.rcaap.pt/detail.jsp?id=oai:www.repository.utl.pt:10400.5/9282

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Ferreira, João Diogo Bernardo Bragança. “Presence of Cryptosporidium baileyi in different Red Grouse (Lagopus lagopus scoticus) moors and its relation with agents of other avian diseases.” 2015. Thesis, Technical University of Lisbon. Accessed January 23, 2021. http://www.rcaap.pt/detail.jsp?id=oai:www.repository.utl.pt:10400.5/9282.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Ferreira, João Diogo Bernardo Bragança. “Presence of Cryptosporidium baileyi in different Red Grouse (Lagopus lagopus scoticus) moors and its relation with agents of other avian diseases.” 2015. Web. 23 Jan 2021.

Vancouver:

Ferreira JDBB. Presence of Cryptosporidium baileyi in different Red Grouse (Lagopus lagopus scoticus) moors and its relation with agents of other avian diseases. [Internet] [Thesis]. Technical University of Lisbon; 2015. [cited 2021 Jan 23]. Available from: http://www.rcaap.pt/detail.jsp?id=oai:www.repository.utl.pt:10400.5/9282.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Ferreira JDBB. Presence of Cryptosporidium baileyi in different Red Grouse (Lagopus lagopus scoticus) moors and its relation with agents of other avian diseases. [Thesis]. Technical University of Lisbon; 2015. Available from: http://www.rcaap.pt/detail.jsp?id=oai:www.repository.utl.pt:10400.5/9282

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universidade Estadual de Campinas

25. Müller, Guilherme Gubert, 1983-. Tacrolimus tópico 0,03% isolado versus uso combinado a olopatadina 0,1% em ceratoconjuntivite vernal grave: Sole topical tacrolimus 0,03% versus combination with olopatadine 0,1% in severe vernal keratoconjunctivitis.

Degree: 2015, Universidade Estadual de Campinas

URL: http://repositorio.unicamp.br/jspui/handle/REPOSIP/312962

► Abstract: Objective: This study sought to evaluate the efficacy of the isolated use of topical tacrolimus compared to the combined use of tacrolimus and olopatadine… (more)

▼ Abstract: Objective: This study sought to evaluate the efficacy of the isolated use of topical tacrolimus compared to the combined use of tacrolimus and olopatadine for the treatment of severe vernal keratoconjunctivitis (VKC). Materials and Methods: In a double-masked study, twenty-one patients with severe VKC were randomized into two groups: 11 in group 1, treated with isolated tacrolimus ointment 0.03%, and 10 in group 2, with olopatadine eye drops 0,1% associated with tacrolimus ointment 0,03%. The clinical signs and symptoms were graded from 0 to 3 and the efficacy of treatment was determined by the difference between the score at the beginning of treatment and the score after 30 days. The clinical impression of improvement as perceived by the evaluator and the self-assessment provided by the patient were scored at day 30 of treatment and compared between the groups. Results: The scores for symptoms decreased between the assessments in both groups (-1.7 ± 3.9, in group 1, and -0.6 ± 1.6, in group 2), with no significant difference between groups (p = 0.205). The scores for clinical signs decreased between the assessments in group 1 (-1.1 ± 2.7) and increased in the group 2 (0.3 ± 0.9), but with no significant differences (p = 0.205). There was no significant difference between the groups regarding the self-assessment (p = 0.659) and the clinical impression of the evaluator (p = 0.387). Conclusions: There was no difference in the effectiveness of tacrolimus 0,03% sole therapy compared with combined olopatadine 0,1% use Advisors/Committee Members: UNIVERSIDADE ESTADUAL DE CAMPINAS (CRUESP), Kara-José, Newton, 1938- (advisor), José, Newton Kara, 1938- (advisor), Universidade Estadual de Campinas. Faculdade de Ciências Médicas (institution), Programa de Pós-Graduação em Ciências Médicas (nameofprogram), Arieta, Carlos Eduardo Leite (committee member), Rocha, Eduardo Melani (committee member), Siqueira, Wallace Chamon Alves de (committee member), Mello, Glauco Henrique Reggiani (committee member).

Subjects/Keywords: Conjuntivite alérgica; Tacrolimo; Antagonistas dos receptores histamínicos H1; Conjunctivitis, Allergic; Tacrolimus; Histamine H1 Antagonists; Antiallergic drugs

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Müller, Guilherme Gubert, 1. (2015). Tacrolimus tópico 0,03% isolado versus uso combinado a olopatadina 0,1% em ceratoconjuntivite vernal grave: Sole topical tacrolimus 0,03% versus combination with olopatadine 0,1% in severe vernal keratoconjunctivitis. (Thesis). Universidade Estadual de Campinas. Retrieved from http://repositorio.unicamp.br/jspui/handle/REPOSIP/312962

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Müller, Guilherme Gubert, 1983-. “Tacrolimus tópico 0,03% isolado versus uso combinado a olopatadina 0,1% em ceratoconjuntivite vernal grave: Sole topical tacrolimus 0,03% versus combination with olopatadine 0,1% in severe vernal keratoconjunctivitis.” 2015. Thesis, Universidade Estadual de Campinas. Accessed January 23, 2021. http://repositorio.unicamp.br/jspui/handle/REPOSIP/312962.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Müller, Guilherme Gubert, 1983-. “Tacrolimus tópico 0,03% isolado versus uso combinado a olopatadina 0,1% em ceratoconjuntivite vernal grave: Sole topical tacrolimus 0,03% versus combination with olopatadine 0,1% in severe vernal keratoconjunctivitis.” 2015. Web. 23 Jan 2021.

Vancouver:

Müller, Guilherme Gubert 1. Tacrolimus tópico 0,03% isolado versus uso combinado a olopatadina 0,1% em ceratoconjuntivite vernal grave: Sole topical tacrolimus 0,03% versus combination with olopatadine 0,1% in severe vernal keratoconjunctivitis. [Internet] [Thesis]. Universidade Estadual de Campinas; 2015. [cited 2021 Jan 23]. Available from: http://repositorio.unicamp.br/jspui/handle/REPOSIP/312962.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Müller, Guilherme Gubert 1. Tacrolimus tópico 0,03% isolado versus uso combinado a olopatadina 0,1% em ceratoconjuntivite vernal grave: Sole topical tacrolimus 0,03% versus combination with olopatadine 0,1% in severe vernal keratoconjunctivitis. [Thesis]. Universidade Estadual de Campinas; 2015. Available from: http://repositorio.unicamp.br/jspui/handle/REPOSIP/312962

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

26. Du, Ningning. Multi-scale Modeling of Deformation and Failure Mechanisms of Al Alloys at Elevated Temperature.

Degree: PhD, Division of Engineering. Mechanics of Solids, 2009, Brown University

URL: https://repository.library.brown.edu/studio/item/bdr:193/

► When deformed at elevated temperature and slow strain rates, some Al alloys exhibits superplasticity, the ability to sustain very large tensile elongations (sometimes over 1000%)… (more)

Subjects/Keywords: Al alloys

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Du, N. (2009). Multi-scale Modeling of Deformation and Failure Mechanisms of Al Alloys at Elevated Temperature. (Doctoral Dissertation). Brown University. Retrieved from https://repository.library.brown.edu/studio/item/bdr:193/

Chicago Manual of Style (16^th Edition):

Du, Ningning. “Multi-scale Modeling of Deformation and Failure Mechanisms of Al Alloys at Elevated Temperature.” 2009. Doctoral Dissertation, Brown University. Accessed January 23, 2021. https://repository.library.brown.edu/studio/item/bdr:193/.

MLA Handbook (7^th Edition):

Du, Ningning. “Multi-scale Modeling of Deformation and Failure Mechanisms of Al Alloys at Elevated Temperature.” 2009. Web. 23 Jan 2021.

Vancouver:

Du N. Multi-scale Modeling of Deformation and Failure Mechanisms of Al Alloys at Elevated Temperature. [Internet] [Doctoral dissertation]. Brown University; 2009. [cited 2021 Jan 23]. Available from: https://repository.library.brown.edu/studio/item/bdr:193/.

Council of Science Editors:

Du N. Multi-scale Modeling of Deformation and Failure Mechanisms of Al Alloys at Elevated Temperature. [Doctoral Dissertation]. Brown University; 2009. Available from: https://repository.library.brown.edu/studio/item/bdr:193/

Technical University of Lisbon

27. Côrte-Real, Mónica Sofia de Albuquerque. Expressão do gene da interleucina-10 na conjuntivite alérgica canina.

Degree: 2015, Technical University of Lisbon

URL: http://www.rcaap.pt/detail.jsp?id=oai:www.repository.utl.pt:10400.5/10379

►

Dissertação de Mestrado Integrado em Medicina Veterinária

A conjuntivite alérgica canina (CAc) é uma doença cuja manifestação clínica ocorre nas pálpebras, na conjuntiva e/ou na… (more)

▼

Dissertação de Mestrado Integrado em Medicina Veterinária

A conjuntivite alérgica canina (CAc) é uma doença cuja manifestação clínica ocorre nas pálpebras, na conjuntiva e/ou na córnea. Caracteriza-se por reações de hipersensibilidade do tipo I e integra frequentemente a sintomatologia da dermatite atópica canina (DAc). Através do estudo realizado no âmbito da presente dissertação de mestrado, pretende-se contribuir para a caracterização da resposta imunitária da CAc. Nesse sentido, um grupo controlo formado por animais saudáveis (n=10) e um grupo de animais atópicos com conjuntivite alérgica (CA) (n=10) integraram a presente experiência. Ambos foram submetidos a um exame dermatológico e oftalmológico completos, em que se procedeu, apenas para o grupo atópico, à classificação da gravidade das lesões com o Canine Atopic Dermatitis Extent and Severity Index – fourth version (CADESI-4), bem como à avaliação quantitativa dos sinais clínicos de CAc (corrimento ocular, epífora, hiperémia conjuntival, prurido, quemose e queratite concomitante) através da atribuição de um valor entre 0 (ausente) e 3 (grave). Subsequentemente, após a aplicação tópica ocular de anestésico, uma amostra de conjuntiva palpebral medindo cerca de 2x2 mm foi colhida e submetida a quantificação, por reação em cadeia da polimerase quantitativa em tempo real (qRT-PCR), dos níveis de expressão de ácido ribonucleico mensageiro (mRNA) do gene da interleucina (IL) -10. A análise estatística foi realizada recorrendo ao teste Mann-Whitney-Wilcoxon e ao teste de correlação de Spearman, sendo que os resultados a seguir apresentados surgem sob a forma de média±desvio-padrão. O score de CADESI-4 nos cães atópicos foi de 22,1±15,72. O score de CA do olho esquerdo foi de 8,9±15,72 e no olho direito 9,1±2,51. A média do score de CA de ambos os olhos foi 9,0±2,30. Os níveis de expressão do gene da IL-10 para o grupo atópico e controlo foram, respetivamente, 0,005±0,0029 e 0,004±0,0024. Verificou-se existir um coeficiente de correlação positivo entre os valores de CADESI-4 e os níveis de expressão do gene da IL-10 (p=0,25), bem como um coeficiente de correlação negativo entre a média do score de CA de ambos os olhos e a expressão do mesmo gene (p=0,35). Desta forma, concluímos que aparentemente o grupo atópico apresenta maiores níveis de expressão do gene da IL-10, o que poderá ser útil para o estudo da fisiopatologia e tratamento de atopia canina e respetiva CA. É necessária a realização de mais estudos para confirmar esta hipótese.

ABSTRACT - INTERLEUKIN-10 GENE EXPRESSION IN CANINE ALLERGIC CONJUNCTIVITIS - Canine allergic conjunctivitis (cAC) is a disease whose clinical manifestation occurs in the eyelids, in the conjunctiva and/or in the cornea. It is characterized by type I hypersensitivity reactions and is often included in the symptoms of canine atopic dermatitis (cAD). Through the study under this master thesis we aim to contribute to the characterization of cAC immune response. Therefore, a control group consisting of healthy animals (n=10) and a…

Advisors/Committee Members: Delgado, Esmeralda Sofia Costa, Gil, Solange Judite Roque Coelho Alves.

Subjects/Keywords: Canine Atopic Dermatitis Extent and Severity Index – fourth version; Conjuntivite alérgica canina; Níveis de expressão de ácido ribonucleico mensageiro do gene da interleucina-10; Score de conjuntivite alérgica; Canine allergic conjunctivitis; Messenger ribonucleic acid expression levels of interleukin-10 gene; Allergic conjunctivitis score

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Côrte-Real, M. S. d. A. (2015). Expressão do gene da interleucina-10 na conjuntivite alérgica canina. (Thesis). Technical University of Lisbon. Retrieved from http://www.rcaap.pt/detail.jsp?id=oai:www.repository.utl.pt:10400.5/10379

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Côrte-Real, Mónica Sofia de Albuquerque. “Expressão do gene da interleucina-10 na conjuntivite alérgica canina.” 2015. Thesis, Technical University of Lisbon. Accessed January 23, 2021. http://www.rcaap.pt/detail.jsp?id=oai:www.repository.utl.pt:10400.5/10379.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Côrte-Real, Mónica Sofia de Albuquerque. “Expressão do gene da interleucina-10 na conjuntivite alérgica canina.” 2015. Web. 23 Jan 2021.

Vancouver:

Côrte-Real MSdA. Expressão do gene da interleucina-10 na conjuntivite alérgica canina. [Internet] [Thesis]. Technical University of Lisbon; 2015. [cited 2021 Jan 23]. Available from: http://www.rcaap.pt/detail.jsp?id=oai:www.repository.utl.pt:10400.5/10379.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Côrte-Real MSdA. Expressão do gene da interleucina-10 na conjuntivite alérgica canina. [Thesis]. Technical University of Lisbon; 2015. Available from: http://www.rcaap.pt/detail.jsp?id=oai:www.repository.utl.pt:10400.5/10379

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

28. Luostarinen, Tapio. Joint effects of infections with different types of human papillomavirus on risk of cervical neoplasia.

Degree: Hjelt Institute, Department of Public Health; Finnish Cancer Registry, Institute for Statistical and Epidemiological Cancer Research, 2015, University of Helsinki

URL: http://hdl.handle.net/10138/154088

► Cervical cancer is the 4th most common cancer in women. In its carcinogenesis human papillomavirus (HPV) 16/18 are most important. HPV6/11 cause benign lesions. A… (more)

▼ Cervical cancer is the 4th most common cancer in women. In its carcinogenesis human papillomavirus (HPV) 16/18 are most important. HPV6/11 cause benign lesions. A small proportion of HPV infection(s) develop into cancer. Therefore, joint effects between HPVs and putative co-factors, Chlamydia trachomatis and smoking, are of interest but largely open. The aims of this work were to understand joint effects of infections with 1) HPV types, 2) HPVs and C. trachomatis, and 3) order of these infections in the carcinogenesis. For the 1st two aims, two case-control studies were nested within cohorts of Nordic biobanks. 1st linkage to cancer registers identified 182 cases of invasive cervical cancer (ICC, 148 squamous cell carcinomas, SCC) with prediagnostic sera until 1994. 2nd linkage with a longer follow-up until 2002 comprised 604 new ICC cases. Incidence density sampled controls were individually matched for age at serum sampling, sample storage time and region. For the 3rd aim, a case-control study in a serial setting was nested within a cohort of Swedish women participating in a cervical cancer screening programme in 1969-1995, and 118 ICCs with age and sampling-time-matched controls were identified. Finally, a case-cohort study in the Finnish Maternity Cohort was based on women with two pregnancies within 5 years. The women were followed on average for 4.8 years, from the 2nd pregnancy sample until the end of 2004. During follow-up, 490 women were diagnosed with cervical high-grade precancer. A comparison subcohort of 2796 women was randomly sampled from age and calendar time strata. IgG antibodies to HPV 6/11/16/18/31/33/45 capsids, and C. trachomatis were determined by ELISA. Serum cotinine, a marker for recent smoking, was measured by immunoassays. HPV and C. trachomatis DNA in smears and biopsy specimen were examined by PCR. HPV DNA-positive specimens were typed. Rate ratios were estimated by conditional logistic or proportional hazards regression. Misclassification of HPV serology was corrected for. In the 1st study, we found no excess risk of cervical carcinoma among women seropositive for both HPV16 and HPV6/11. In the 2nd study, there was excess risk, but the joint effect was again significantly smaller than the expected joint effects. Finally, if infection with HPV6 preceded infection with high-risk HPV31, there was no material excess risk of in situ cervical carcinoma. The smaller than expected joint effect between HPV types was probably due to a cell-mediated immune response to past, natural HPV6/11 infection, of which the serum antibodies were a surrogate. The risk of ICC was highly increased not only among women whose 1st smear was HPV DNA-positive but also among C. trachomatis DNA-positive women. The risk was even higher among HPV or C. trachomatis DNA positives both at the start and end of follow-up. The risk of in situ cervical carcinoma was highly increased among women whose HPV18/45 and C. trachomatis infections were virtually concomitant. The risk of SCC was increased related to C.…

Subjects/Keywords: epidemiologia; epidemiologia

…määrittämisen vaikeaksi (Clifford et al. 2011). Tunnetaan myös pienen riskin (lr)… …developed countries (Ferlay et al. 2013). The aetiology of invasive cervical carcinoma… …previous C. trachomatis infection (Samoff et al. 2005, Silins et al. 2005), which is… …associated with cervical neoplasia (Lehtinen et al. 2011). Smoking has been associated… …positive women (Kapeu et al. 2009). Cervical co-infection with at least two HPV types…

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Luostarinen, T. (2015). Joint effects of infections with different types of human papillomavirus on risk of cervical neoplasia. (Doctoral Dissertation). University of Helsinki. Retrieved from http://hdl.handle.net/10138/154088

Chicago Manual of Style (16^th Edition):

Luostarinen, Tapio. “Joint effects of infections with different types of human papillomavirus on risk of cervical neoplasia.” 2015. Doctoral Dissertation, University of Helsinki. Accessed January 23, 2021. http://hdl.handle.net/10138/154088.

MLA Handbook (7^th Edition):

Luostarinen, Tapio. “Joint effects of infections with different types of human papillomavirus on risk of cervical neoplasia.” 2015. Web. 23 Jan 2021.

Vancouver:

Luostarinen T. Joint effects of infections with different types of human papillomavirus on risk of cervical neoplasia. [Internet] [Doctoral dissertation]. University of Helsinki; 2015. [cited 2021 Jan 23]. Available from: http://hdl.handle.net/10138/154088.

Council of Science Editors:

Luostarinen T. Joint effects of infections with different types of human papillomavirus on risk of cervical neoplasia. [Doctoral Dissertation]. University of Helsinki; 2015. Available from: http://hdl.handle.net/10138/154088

Universidade Federal de Mato Grosso do Sul

29. Patusco, Luiz Armando Pereira. Broncoscopia: experiência do Hospital Universitário da Universidade Federal de Mato Grosso do Sul .

Degree: 2011, Universidade Federal de Mato Grosso do Sul

URL: http://repositorio.cbc.ufms.br:8080/jspui/handle/123456789/1028

► Realizou-se um estudo descritivo e retrospectivo a partir da revisão de 2004 registros médicos referentes a exames de broncoscopia realizados no Serviço de Pneumologia do… (more)

Subjects/Keywords: Broncoscopia; Epidemiologia; Pneumologia

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Patusco, L. A. P. (2011). Broncoscopia: experiência do Hospital Universitário da Universidade Federal de Mato Grosso do Sul . (Thesis). Universidade Federal de Mato Grosso do Sul. Retrieved from http://repositorio.cbc.ufms.br:8080/jspui/handle/123456789/1028

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Patusco, Luiz Armando Pereira. “Broncoscopia: experiência do Hospital Universitário da Universidade Federal de Mato Grosso do Sul .” 2011. Thesis, Universidade Federal de Mato Grosso do Sul. Accessed January 23, 2021. http://repositorio.cbc.ufms.br:8080/jspui/handle/123456789/1028.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Patusco, Luiz Armando Pereira. “Broncoscopia: experiência do Hospital Universitário da Universidade Federal de Mato Grosso do Sul .” 2011. Web. 23 Jan 2021.

Vancouver:

Patusco LAP. Broncoscopia: experiência do Hospital Universitário da Universidade Federal de Mato Grosso do Sul . [Internet] [Thesis]. Universidade Federal de Mato Grosso do Sul; 2011. [cited 2021 Jan 23]. Available from: http://repositorio.cbc.ufms.br:8080/jspui/handle/123456789/1028.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Patusco LAP. Broncoscopia: experiência do Hospital Universitário da Universidade Federal de Mato Grosso do Sul . [Thesis]. Universidade Federal de Mato Grosso do Sul; 2011. Available from: http://repositorio.cbc.ufms.br:8080/jspui/handle/123456789/1028

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

30. OLIVEIRA, Renata Mendes Batista de. Produção de imunoglobulina humana: nova aplicação terapêutica para o tratamento da dengue .

Degree: 2012, Universidade Federal de Pernambuco

URL: https://repositorio.ufpe.br/handle/123456789/25583

► A dengue é a mais importante arbovirose que afeta o homem, constituindo um sério problema de saúde pública. O vírus causador pertence à família Flaviviridae,… (more)

Subjects/Keywords: Dengue; Imunoglobulinas; Epidemiologia

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

OLIVEIRA, R. M. B. d. (2012). Produção de imunoglobulina humana: nova aplicação terapêutica para o tratamento da dengue . (Masters Thesis). Universidade Federal de Pernambuco. Retrieved from https://repositorio.ufpe.br/handle/123456789/25583

Chicago Manual of Style (16^th Edition):

OLIVEIRA, Renata Mendes Batista de. “Produção de imunoglobulina humana: nova aplicação terapêutica para o tratamento da dengue .” 2012. Masters Thesis, Universidade Federal de Pernambuco. Accessed January 23, 2021. https://repositorio.ufpe.br/handle/123456789/25583.

MLA Handbook (7^th Edition):

OLIVEIRA, Renata Mendes Batista de. “Produção de imunoglobulina humana: nova aplicação terapêutica para o tratamento da dengue .” 2012. Web. 23 Jan 2021.

Vancouver:

OLIVEIRA RMBd. Produção de imunoglobulina humana: nova aplicação terapêutica para o tratamento da dengue . [Internet] [Masters thesis]. Universidade Federal de Pernambuco; 2012. [cited 2021 Jan 23]. Available from: https://repositorio.ufpe.br/handle/123456789/25583.

Council of Science Editors:

OLIVEIRA RMBd. Produção de imunoglobulina humana: nova aplicação terapêutica para o tratamento da dengue . [Masters Thesis]. Universidade Federal de Pernambuco; 2012. Available from: https://repositorio.ufpe.br/handle/123456789/25583

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Open Access Theses and Dissertations