subject:(canine distemper virus)

University of Pretoria

1. Woma, Timothy Yusufu. The isolation and genetic characterization of canine distemper viruses from domestic dogs (Canis familiaris) in South Africa .

Degree: 2009, University of Pretoria

URL: http://upetd.up.ac.za/thesis/available/etd-07142009-151317/

► Studies comparing canine distemper virus (CDV) strains from Africa with that of previously described lineages have been hampered due to a lack of field strains… (more)

▼ Studies comparing canine distemper virus (CDV) strains from Africa with that of previously described lineages have been hampered due to a lack of field strains for in vitro experiments. There are no reports of CDV isolations in southern Africa, and although CDV is said to have geographically distinct lineages, molecular information of African strains has not yet been documented. Clinical specimens consisting of whole blood, spleen, lungs, brain and cerebrospinal fluid from dogs with clinical signs suggestive of distemper were obtained from private veterinary practices and diagnostic laboratories in Gauteng province, South Africa. One hundred and sixty two specimens from 124 dogs were inoculated into Vero cells expressing canine signalling lymphocyte activation molecule (Vero.DogSLAM). Cytopathic effects (CPE) in the form of syncytia formation and cell necrosis were observed in 33 (20.4%) specimens within 24 hours of inoculation and the presence of CDV was confirmed with the aid of the direct fluorescent antibody test and electronmicroscopy (EM). Viruses isolated in cell cultures were subjected to reverse transcription – polymerase chain reaction (RT-PCR), and the complete H gene was sequenced and phylogenetically analysed with other strains from GenBank. The animals all displayed the catarrhal, systemic, or nervous signs of the disease. Four of the dogs positive for CDV by viral isolation had a history of prior vaccinations to canine distemper. Seventy three percent of all positive dogs were less than 12 months old. There was no breed or sex predisposition to CDV infection in domestic dogs. Phylogenetic comparisons of the complete H gene of CDV isolates from different parts of the world (available in GenBank) with wild-type South African isolates revealed nine clades. All South African isolates form a separate African clade of their own and thus are clearly separated from the American, European, Asian, Arctic and vaccine virus clades. It is likely that only the ‘African lineage’ of CDV may be circulating in South Africa currently, and the viruses isolated from dogs vaccinated against CDV are not the result of reversion to virulence of vaccine strains, but infection with wild-type strains. Copyright Advisors/Committee Members: Van Vuuren, Moritz (advisor).

Subjects/Keywords: Canine distemper virus; Domestic dogs; South Africa

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APA (6^th Edition):

Woma, T. Y. (2009). The isolation and genetic characterization of canine distemper viruses from domestic dogs (Canis familiaris) in South Africa . (Masters Thesis). University of Pretoria. Retrieved from http://upetd.up.ac.za/thesis/available/etd-07142009-151317/

Chicago Manual of Style (16^th Edition):

Woma, Timothy Yusufu. “The isolation and genetic characterization of canine distemper viruses from domestic dogs (Canis familiaris) in South Africa .” 2009. Masters Thesis, University of Pretoria. Accessed March 04, 2021. http://upetd.up.ac.za/thesis/available/etd-07142009-151317/.

MLA Handbook (7^th Edition):

Woma, Timothy Yusufu. “The isolation and genetic characterization of canine distemper viruses from domestic dogs (Canis familiaris) in South Africa .” 2009. Web. 04 Mar 2021.

Vancouver:

Woma TY. The isolation and genetic characterization of canine distemper viruses from domestic dogs (Canis familiaris) in South Africa . [Internet] [Masters thesis]. University of Pretoria; 2009. [cited 2021 Mar 04]. Available from: http://upetd.up.ac.za/thesis/available/etd-07142009-151317/.

Council of Science Editors:

Woma TY. The isolation and genetic characterization of canine distemper viruses from domestic dogs (Canis familiaris) in South Africa . [Masters Thesis]. University of Pretoria; 2009. Available from: http://upetd.up.ac.za/thesis/available/etd-07142009-151317/

The Ohio State University

2. Higgins, Robert James. Studies of the pathogenesis of encephalomyelitis in gnotobiotic dogs induced by canine distemper virus.

Degree: PhD, Graduate School, 1980, The Ohio State University

URL: http://rave.ohiolink.edu/etdc/view?acc_num=osu1487152450442532

Subjects/Keywords: Biology; Encephalomyelitis; Canine distemper virus

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APA (6^th Edition):

Higgins, R. J. (1980). Studies of the pathogenesis of encephalomyelitis in gnotobiotic dogs induced by canine distemper virus. (Doctoral Dissertation). The Ohio State University. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=osu1487152450442532

Chicago Manual of Style (16^th Edition):

Higgins, Robert James. “Studies of the pathogenesis of encephalomyelitis in gnotobiotic dogs induced by canine distemper virus.” 1980. Doctoral Dissertation, The Ohio State University. Accessed March 04, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487152450442532.

MLA Handbook (7^th Edition):

Higgins, Robert James. “Studies of the pathogenesis of encephalomyelitis in gnotobiotic dogs induced by canine distemper virus.” 1980. Web. 04 Mar 2021.

Vancouver:

Higgins RJ. Studies of the pathogenesis of encephalomyelitis in gnotobiotic dogs induced by canine distemper virus. [Internet] [Doctoral dissertation]. The Ohio State University; 1980. [cited 2021 Mar 04]. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=osu1487152450442532.

Council of Science Editors:

Higgins RJ. Studies of the pathogenesis of encephalomyelitis in gnotobiotic dogs induced by canine distemper virus. [Doctoral Dissertation]. The Ohio State University; 1980. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=osu1487152450442532

3. Bellan, Steven Edward. Applications of Data-driven Modeling to Infectious Diseases in Africa: Anthrax in Wildlife and HIV in Humans.

Degree: Environmental Science, Policy, & Management, 2012, University of California – Berkeley

URL: http://www.escholarship.org/uc/item/4xx9c4f0

► The goal of epidemiology is to identify the biological, behavioral, and environmental causes of health outcomes or diseases and apply this knowledge to the development… (more)

Subjects/Keywords: Biology; Health sciences; Animal diseases; anthrax; canine distemper virus; HIV; jackal; rabies; zebra

9 more images…

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APA (6^th Edition):

Bellan, S. E. (2012). Applications of Data-driven Modeling to Infectious Diseases in Africa: Anthrax in Wildlife and HIV in Humans. (Thesis). University of California – Berkeley. Retrieved from http://www.escholarship.org/uc/item/4xx9c4f0

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Bellan, Steven Edward. “Applications of Data-driven Modeling to Infectious Diseases in Africa: Anthrax in Wildlife and HIV in Humans.” 2012. Thesis, University of California – Berkeley. Accessed March 04, 2021. http://www.escholarship.org/uc/item/4xx9c4f0.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Bellan, Steven Edward. “Applications of Data-driven Modeling to Infectious Diseases in Africa: Anthrax in Wildlife and HIV in Humans.” 2012. Web. 04 Mar 2021.

Vancouver:

Bellan SE. Applications of Data-driven Modeling to Infectious Diseases in Africa: Anthrax in Wildlife and HIV in Humans. [Internet] [Thesis]. University of California – Berkeley; 2012. [cited 2021 Mar 04]. Available from: http://www.escholarship.org/uc/item/4xx9c4f0.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Bellan SE. Applications of Data-driven Modeling to Infectious Diseases in Africa: Anthrax in Wildlife and HIV in Humans. [Thesis]. University of California – Berkeley; 2012. Available from: http://www.escholarship.org/uc/item/4xx9c4f0

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Pretoria

4. Haig, D.A. Canine distemper : immunisation with avianised virus.

Degree: DVSc, Companion Animal Clinical Studies, 1953, University of Pretoria

URL: http://hdl.handle.net/2263/61731

No abstract

Subjects/Keywords: UCTD; Dogs – Virus doseases; Canine distemper

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Haig, D. A. (1953). Canine distemper : immunisation with avianised virus. (Doctoral Dissertation). University of Pretoria. Retrieved from http://hdl.handle.net/2263/61731

Chicago Manual of Style (16^th Edition):

Haig, D A. “Canine distemper : immunisation with avianised virus.” 1953. Doctoral Dissertation, University of Pretoria. Accessed March 04, 2021. http://hdl.handle.net/2263/61731.

MLA Handbook (7^th Edition):

Haig, D A. “Canine distemper : immunisation with avianised virus.” 1953. Web. 04 Mar 2021.

Vancouver:

Haig DA. Canine distemper : immunisation with avianised virus. [Internet] [Doctoral dissertation]. University of Pretoria; 1953. [cited 2021 Mar 04]. Available from: http://hdl.handle.net/2263/61731.

Council of Science Editors:

Haig DA. Canine distemper : immunisation with avianised virus. [Doctoral Dissertation]. University of Pretoria; 1953. Available from: http://hdl.handle.net/2263/61731

University of Georgia

5. Fung, Hou-Ming Lillian. Community level canine health assessment.

Degree: 2014, University of Georgia

URL: http://hdl.handle.net/10724/28267

► Domestic dogs often serve as reservoir hosts for many zoonotic and wildlife pathogens. This study evaluates the role dog health plays in infectious disease transmission,… (more)

Subjects/Keywords: Zoonoses; Chagas disease; Trypanosoma cruzi; Intestinal helminths; Neglected Tropical Diseases; Canine Distemper Virus

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Fung, H. L. (2014). Community level canine health assessment. (Thesis). University of Georgia. Retrieved from http://hdl.handle.net/10724/28267

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Fung, Hou-Ming Lillian. “Community level canine health assessment.” 2014. Thesis, University of Georgia. Accessed March 04, 2021. http://hdl.handle.net/10724/28267.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Fung, Hou-Ming Lillian. “Community level canine health assessment.” 2014. Web. 04 Mar 2021.

Vancouver:

Fung HL. Community level canine health assessment. [Internet] [Thesis]. University of Georgia; 2014. [cited 2021 Mar 04]. Available from: http://hdl.handle.net/10724/28267.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Fung HL. Community level canine health assessment. [Thesis]. University of Georgia; 2014. Available from: http://hdl.handle.net/10724/28267

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Montana

6. Weckworth, Julie Kay. ECOLOGY, EPIDEMIOLOGY, AND EVOLUTIONARY GENETICS OF CANINE DISTEMPER VIRUS SPILLOVER IN AFRICAN LIONS.

Degree: PhD, 2018, University of Montana

URL: https://scholarworks.umt.edu/etd/11221

► The impact of emerging infectious diseases (EIDs) on the health and persistence of wildlife populations is an increasing conservation concern. Large carnivores are particularly… (more)

▼ The impact of emerging infectious diseases (EIDs) on the health and persistence of wildlife populations is an increasing conservation concern. Large carnivores are particularly vulnerable to EID impacts because they often occur in small, isolated populations with demographic and genetic challenges to long-term persistence. Ecological forces that isolate carnivore populations, e.g. agricultural intensification, simultaneously increase the probability of disease exposure from domestic species and can amplify population susceptibility to infection. Canine distemper virus emerged as a conservation threat to African lions when an explosive epizootic caused the death or disappearance of a third of the Serengeti lion population in 1994. This same lion population was exposed to CDV on several other occasions without overt clinical infection. For my dissertation, I investigated ecological, epidemiological, and evolutionary factors contributing to the emergence and outcome of CDV infection in this globally important population. Based on phylodynamic analyses of annotated sequence data I found that the lethal outbreak in 1994 was likely catalyzed by a single spillover event from a canid reservoir, and fueled by repeated transmissions from non-canid hosts, e.g. spotted hyenas. Distinct genotypes were found in canid and non-canid hosts suggesting that there is a host barrier to CDV spillover, which might limit lethal outbreaks in lions. Expanding the spatiotemporal scope of the phylogenetic analysis I found that Serengeti lions were not epidemiologically connected to other carnivore populations at the regional or continental scale. Recurrent CDV infection in Serengeti lions was likely due to local persistence in the domestic and/or wild carnivore community. Finally, based on phylogenetic and selection analyses I identified 25 candidate markers in the CDV genome potentially associated with the pathogenicity of infection in lions during the 1994 outbreak. These were mostly found in functional domains related to transcription and replication, and viral egress, implicating these processes as possible barriers to disease in lions. Mutations at two of the markers were shared with two CDV outbreaks in North America that caused clinical infection in African lions. Surveillance for these two mutations in circulating strains may inform CDV risk assessment in lion populations of conservation concern.

Subjects/Keywords: African lion; Canine distemper virus; Cross-species transmission; Disease spillover; Evolutionary genetics; Molecular epidemiology

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APA (6^th Edition):

Weckworth, J. K. (2018). ECOLOGY, EPIDEMIOLOGY, AND EVOLUTIONARY GENETICS OF CANINE DISTEMPER VIRUS SPILLOVER IN AFRICAN LIONS. (Doctoral Dissertation). University of Montana. Retrieved from https://scholarworks.umt.edu/etd/11221

Chicago Manual of Style (16^th Edition):

Weckworth, Julie Kay. “ECOLOGY, EPIDEMIOLOGY, AND EVOLUTIONARY GENETICS OF CANINE DISTEMPER VIRUS SPILLOVER IN AFRICAN LIONS.” 2018. Doctoral Dissertation, University of Montana. Accessed March 04, 2021. https://scholarworks.umt.edu/etd/11221.

MLA Handbook (7^th Edition):

Weckworth, Julie Kay. “ECOLOGY, EPIDEMIOLOGY, AND EVOLUTIONARY GENETICS OF CANINE DISTEMPER VIRUS SPILLOVER IN AFRICAN LIONS.” 2018. Web. 04 Mar 2021.

Vancouver:

Weckworth JK. ECOLOGY, EPIDEMIOLOGY, AND EVOLUTIONARY GENETICS OF CANINE DISTEMPER VIRUS SPILLOVER IN AFRICAN LIONS. [Internet] [Doctoral dissertation]. University of Montana; 2018. [cited 2021 Mar 04]. Available from: https://scholarworks.umt.edu/etd/11221.

Council of Science Editors:

Weckworth JK. ECOLOGY, EPIDEMIOLOGY, AND EVOLUTIONARY GENETICS OF CANINE DISTEMPER VIRUS SPILLOVER IN AFRICAN LIONS. [Doctoral Dissertation]. University of Montana; 2018. Available from: https://scholarworks.umt.edu/etd/11221

University of Missouri – Columbia

7. Pardo, Ingrid D. R. Phylogenetic characterization of canine distemper viruses detected in naturally infected North American dogs.

Degree: 2006, University of Missouri – Columbia

URL: http://hdl.handle.net/10355/4542

► In 2004, dogs with clinical signs suggestive of viral disease known as canine distemper virus (CD) were referred to the University of Missouri Veterinary Diagnostic… (more)

Subjects/Keywords: Canine distemper – Genetic aspects; Canine distemper – Genetic aspects; Canine distemper virus – Genetic aspects; Canine distemper virus – Genetic aspects; Dogs – Diseases – Genetic aspects; Dogs – Diseases – Genetic aspects

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Pardo, I. D. R. (2006). Phylogenetic characterization of canine distemper viruses detected in naturally infected North American dogs. (Thesis). University of Missouri – Columbia. Retrieved from http://hdl.handle.net/10355/4542

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Pardo, Ingrid D R. “Phylogenetic characterization of canine distemper viruses detected in naturally infected North American dogs.” 2006. Thesis, University of Missouri – Columbia. Accessed March 04, 2021. http://hdl.handle.net/10355/4542.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Pardo, Ingrid D R. “Phylogenetic characterization of canine distemper viruses detected in naturally infected North American dogs.” 2006. Web. 04 Mar 2021.

Vancouver:

Pardo IDR. Phylogenetic characterization of canine distemper viruses detected in naturally infected North American dogs. [Internet] [Thesis]. University of Missouri – Columbia; 2006. [cited 2021 Mar 04]. Available from: http://hdl.handle.net/10355/4542.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Pardo IDR. Phylogenetic characterization of canine distemper viruses detected in naturally infected North American dogs. [Thesis]. University of Missouri – Columbia; 2006. Available from: http://hdl.handle.net/10355/4542

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universidade Federal de Santa Maria

8. Renata Dezengrini. SOROPREVALÊNCIA DE INFECÇÕES VÍRICAS EM CÃES DE SANTA MARIA, RS; SELEÇÃO E CARACTERIZAÇÃO DE LINHAGENS CELULARES RESISTENTES AO VÍRUS DA DIARRÉIA VIRAL BOVINA.

Degree: 2006, Universidade Federal de Santa Maria

URL: http://coralx.ufsm.br/tede/tde_busca/arquivo.php?codArquivo=1189

► O presente trabalho relata um inquérito sorológico das principais infecções víricas de cães em Santa Maria, RS, Brasil e a obtenção de linhagens celulares de… (more)

▼ O presente trabalho relata um inquérito sorológico das principais infecções víricas de cães em Santa Maria, RS, Brasil e a obtenção de linhagens celulares de origem canina, suína e leporina resistentes ao vírus da Diarréia Viral Bovina (BVDV). As infecções pelo vírus da cinomose (CDV), parvovírus (CPV), adenovírus (CAV) e coronavírus (CCoV) são importantes causas de morbidade e de mortalidade em cães em todo o mundo. Com o objetivo de determinar a prevalência de anticorpos contra esses vírus na população canina da cidade de Santa Maria, coletou-se amostras de sangue de 817 cães não-vacinados, em 14 bairros. Estas foram testadas pela técnica de soroneutralização (CDV, CAV e CCoV) ou inibição da hemaglutinação (CPV). Anticorpos específicos contra o CDV foram detectados em 27,3% (223/817) das amostras, contra o CPV em 68,7% (561/817), contra o CAV em 43% (353/817) e contra o CCoV em 50,4% (412/817) dos cães. Esses resultados demonstram que esses vírus estão difundidos na população canina dos bairros da cidade. Por outro lado, demonstram também que uma parte considerável da população é soronegativa e, portanto está desprotegida contra esses agentes, indicando a necessidade de se ampliar os programas de vacinação para essas infecções. Durante a padronização das técnicas sorológicas e expansão dos cultivos celulares para amplificação dos vírus, detectou-se a contaminação da linhagem de células caninas MDCK com o BVDV, o principal vírus contaminante de cultivos celulares. A contaminação inadvertida de cultivos celulares com o BVDV pode representar um sério problema para o diagnóstico virológico, pesquisa e produção de imunobiológicos. A segunda parte dessa dissertação descreve a produção e caracterização de três linhagens celulares resistentes ao BVDV, obtidas a partir das células parentais de origem canina (MDCK), suína (PK-15) e leporina (RK-13) que estavam contaminadas com o BVDV. Essas células foram submetidas a quatro ciclos de infecção com uma cepa citolítica de BVDV. As células que sobreviveram a infecção lítica foram clonadas, expandidas e testadas para a sua susceptibilidade ao BVDV e outros vírus de interesse. A resistência ao BVDV foi investigada pela pesquisa de antígenos virais por imunofluorescência indireta e por cocultivo com células susceptíveis após a inoculação do vírus em altos títulos. As três linhagens celulares demonstraram ser resistentes a três cepas-padrão (Singer, NADL e Oregon) e a 10 isolados de campo do BVDV. A inoculação do BVDV nessas células com uma multiplicidade de infecção de 10 DICC50/célula resultou em freqüências de infecção de <10-5 para as células MDCK-R e PK-15R; e de 3,3x10-4 para as células RK-13R. Comparando-se com as células parentais, verificou-se que as linhagens resistentes são >10.000 (MDCK-R), >20.000 (PK-15R) e 600 (RK-13R) vezes menos susceptíveis ao BVDV. A inoculação do vírus nas células resistentes na presença de polietilenoglicol (PEG) resultou em um aumento na susceptibilidade dessas células na ordem de >437 (MDCK-R), >346 (PK-15R) e 87 vezes (RK-13R). Esses… Advisors/Committee Members: Eduardo Furtado Flores, Luciane Teresinha Lovato.

Subjects/Keywords: resistant cells; células resistentes; contaminação celular; coronavírus canino; adenovírus canino; parvovírus canino; vírus da cinomose; MEDICINA VETERINARIA; canine adenovirus; canine parvovirus; canine distemper virus; canine coronavirus; cell contamination

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Dezengrini, R. (2006). SOROPREVALÊNCIA DE INFECÇÕES VÍRICAS EM CÃES DE SANTA MARIA, RS; SELEÇÃO E CARACTERIZAÇÃO DE LINHAGENS CELULARES RESISTENTES AO VÍRUS DA DIARRÉIA VIRAL BOVINA. (Thesis). Universidade Federal de Santa Maria. Retrieved from http://coralx.ufsm.br/tede/tde_busca/arquivo.php?codArquivo=1189

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Dezengrini, Renata. “SOROPREVALÊNCIA DE INFECÇÕES VÍRICAS EM CÃES DE SANTA MARIA, RS; SELEÇÃO E CARACTERIZAÇÃO DE LINHAGENS CELULARES RESISTENTES AO VÍRUS DA DIARRÉIA VIRAL BOVINA.” 2006. Thesis, Universidade Federal de Santa Maria. Accessed March 04, 2021. http://coralx.ufsm.br/tede/tde_busca/arquivo.php?codArquivo=1189.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Dezengrini, Renata. “SOROPREVALÊNCIA DE INFECÇÕES VÍRICAS EM CÃES DE SANTA MARIA, RS; SELEÇÃO E CARACTERIZAÇÃO DE LINHAGENS CELULARES RESISTENTES AO VÍRUS DA DIARRÉIA VIRAL BOVINA.” 2006. Web. 04 Mar 2021.

Vancouver:

Dezengrini R. SOROPREVALÊNCIA DE INFECÇÕES VÍRICAS EM CÃES DE SANTA MARIA, RS; SELEÇÃO E CARACTERIZAÇÃO DE LINHAGENS CELULARES RESISTENTES AO VÍRUS DA DIARRÉIA VIRAL BOVINA. [Internet] [Thesis]. Universidade Federal de Santa Maria; 2006. [cited 2021 Mar 04]. Available from: http://coralx.ufsm.br/tede/tde_busca/arquivo.php?codArquivo=1189.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Dezengrini R. SOROPREVALÊNCIA DE INFECÇÕES VÍRICAS EM CÃES DE SANTA MARIA, RS; SELEÇÃO E CARACTERIZAÇÃO DE LINHAGENS CELULARES RESISTENTES AO VÍRUS DA DIARRÉIA VIRAL BOVINA. [Thesis]. Universidade Federal de Santa Maria; 2006. Available from: http://coralx.ufsm.br/tede/tde_busca/arquivo.php?codArquivo=1189

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Technical University of Lisbon

9. Castanheira, Pedro Joaquim de Carvalho Mendes. Rastreio virológico de cães errantes da cidade de Vila do Maio, Cabo Verde.

Degree: 2012, Technical University of Lisbon

URL: http://www.rcaap.pt/detail.jsp?id=oai:www.repository.utl.pt:10400.5/4835

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Dissertação de Mestrado Integrado em Medicina Veterinária

As infeções pelo parvovírus canino (CPV), vírus da esgana canina (CDV) e coronavírus canino (CCoV) são importantes causas… (more)

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Dissertação de Mestrado Integrado em Medicina Veterinária

As infeções pelo parvovírus canino (CPV), vírus da esgana canina (CDV) e coronavírus canino (CCoV) são importantes causas de morbilidade e de mortalidade em cães de todo o mundo. Contudo, aparentemente não se conhece a sua incidência e prevalência no arquipélago de Cabo Verde. Para determinar a prevalência dessas infeções na população canina da cidade de Vila do Maio, situada na ilha do Maio, foram colhidas amostras a partir cães errantes desse local em dois períodos distintos: no ano de 2010 obtiveram-se 53 zaragatoas retais e em 2011 colheram-se 93 zaragatoas retais e 88 amostras de sangue, existindo 56 animais coincidentes nos dois tipos de amostra. Do total de 125 cães amostrados neste último ano apenas 2 eram vacinados. Testou-se a presença de ácido nucleico viral por real-time PCR e real-time RT-PCR a partir das zaragatoas e analisou-se a presença de anticorpos contra CPV e CDV nas amostras de sangue. Em relação a 2010, detetou-se ácido nucleico viral em 43,3% (23/53) das amostras para CPV, 11,3% (6/53) para CDV e 1,9% (1/53) para CCoV. Em 2011, a prevalência de CPV foi de 44,1% (41/93), 0% para CDV e 1,1% (1/93) para CCoV. Ainda neste ano, anticorpos contra o CPV foram detetados em 71,6% (63/88) das amostras de sangue e a seroprevalência no caso do CDV foi de 51,1% (45/88). A presença de anticorpos anti-CPV foi significativamente superior nos cães mais velhos e observou-se uma tendência crescente de seropositividade com o aumento da idade no caso do CDV, embora não fosse estatisticamente significativo. Não se registaram diferenças de seroprevalência em relação ao género dos animais. Este trabalho demonstra a importância da vigilância epidemiológica molecular em populações de animais errantes e domésticos das cidades, uma vez que o seu elevado número possibilita a disseminação e manutenção dos vírus nestes locais, que pode conduzir a uma elevada mortalidade em populações com reduzidas taxas de vacinação. Para além disso, estes animais podem constituir reservatórios das doenças, havendo possibilidade de transmissão às populações de animais selvagens através de contactos ocasionais. Seria importante identificar a fauna silvestre suscetível da ilha do Maio, para se avaliar até que ponto os vírus que se encontram em Vila do Maio podem constituir um perigo para esses animais.

ABSTRACT - VIROLOGICAL SURVEY IN STRAY DOGS OF VILA DO MAIO, CAPE VERDE - Infections caused by canine parvovirus (CPV), canine distemper virus (CDV) and canine coronavirus (CCoV) are important causes of morbidity and mortality in dogs worldwide. However, it seems that the incidence and prevalence of these viruses is unknown in the archipelago of Cape Verde. To determine the prevalence of these infections in Vila do Maio canine population, located in Maio island, samples were collected from stray dogs in two distinct periods: in 2010, fifty three rectal swabs were obtained and in 2011 a total of 93 rectal swabs and 88 blood samples were collected, and 56 animals were coincident in…

Advisors/Committee Members: Duarte, Ana Isabel Simões Pereira.

Subjects/Keywords: Rastreio virológico; epidemiologia molecular; parvovírus canino; vírus da esgana canina; coronavírus canino; Cabo Verde; virological survey; molecular epidemiology; canine parvovirus; canine distemper virus; canine coronavirus; Cape Verde

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Castanheira, P. J. d. C. M. (2012). Rastreio virológico de cães errantes da cidade de Vila do Maio, Cabo Verde. (Thesis). Technical University of Lisbon. Retrieved from http://www.rcaap.pt/detail.jsp?id=oai:www.repository.utl.pt:10400.5/4835

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Castanheira, Pedro Joaquim de Carvalho Mendes. “Rastreio virológico de cães errantes da cidade de Vila do Maio, Cabo Verde.” 2012. Thesis, Technical University of Lisbon. Accessed March 04, 2021. http://www.rcaap.pt/detail.jsp?id=oai:www.repository.utl.pt:10400.5/4835.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Castanheira, Pedro Joaquim de Carvalho Mendes. “Rastreio virológico de cães errantes da cidade de Vila do Maio, Cabo Verde.” 2012. Web. 04 Mar 2021.

Vancouver:

Castanheira PJdCM. Rastreio virológico de cães errantes da cidade de Vila do Maio, Cabo Verde. [Internet] [Thesis]. Technical University of Lisbon; 2012. [cited 2021 Mar 04]. Available from: http://www.rcaap.pt/detail.jsp?id=oai:www.repository.utl.pt:10400.5/4835.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Castanheira PJdCM. Rastreio virológico de cães errantes da cidade de Vila do Maio, Cabo Verde. [Thesis]. Technical University of Lisbon; 2012. Available from: http://www.rcaap.pt/detail.jsp?id=oai:www.repository.utl.pt:10400.5/4835

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

The Ohio State University

10. Axthelm, Michael K. Studies on the entry and persistence of canine distemper virus in the central nervous system.

Degree: PhD, Graduate School, 1985, The Ohio State University

URL: http://rave.ohiolink.edu/etdc/view?acc_num=osu1487261553058067

Subjects/Keywords: Health Sciences; Canine distemper virus; Veterinary virology; Virology

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Axthelm, M. K. (1985). Studies on the entry and persistence of canine distemper virus in the central nervous system. (Doctoral Dissertation). The Ohio State University. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=osu1487261553058067

Chicago Manual of Style (16^th Edition):

Axthelm, Michael K. “Studies on the entry and persistence of canine distemper virus in the central nervous system.” 1985. Doctoral Dissertation, The Ohio State University. Accessed March 04, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487261553058067.

MLA Handbook (7^th Edition):

Axthelm, Michael K. “Studies on the entry and persistence of canine distemper virus in the central nervous system.” 1985. Web. 04 Mar 2021.

Vancouver:

Axthelm MK. Studies on the entry and persistence of canine distemper virus in the central nervous system. [Internet] [Doctoral dissertation]. The Ohio State University; 1985. [cited 2021 Mar 04]. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=osu1487261553058067.

Council of Science Editors:

Axthelm MK. Studies on the entry and persistence of canine distemper virus in the central nervous system. [Doctoral Dissertation]. The Ohio State University; 1985. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=osu1487261553058067

Universidade do Rio Grande do Sul

11. Budaszewski, Renata da Fontoura. Estudos sobre vacinologia e evolução do vírus da cinomose canina.

Degree: 2017, Universidade do Rio Grande do Sul

URL: http://hdl.handle.net/10183/163434

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O vírus da cinomose canina (CDV) é um importante patógeno de cães domésticos e carnívoros selvagens. A infecção pelo CDV é relevante a nível mundial… (more)

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O vírus da cinomose canina (CDV) é um importante patógeno de cães domésticos e carnívoros selvagens. A infecção pelo CDV é relevante a nível mundial e está associada com alta morbidade e mortalidade. Em diversos países a cinomose é considerada controlada pelo uso de vacinas, no entanto, no Brasil ainda é endêmica, principalmente devido ao grande número de animais não domiciliados. Além disso, surtos em cães e várias espécies de animais silvestres ocorrem com frequência, dizimando populações ameaçadas. As vacinas vivas atenuadas são seguras para cães, mas seu uso não é aconselhado em espécies altamente suscetíveis à infecção pelo CDV. Também os relatos de surtos de cinomose em cães supostamente vacinados levantam a hipótese de que as vacinas disponíveis no mercado podem não ser eficientes frente a algumas cepas de campo. Com o objetivo de gerar dados acerca dos mecanismos de evolução do CDV e desenvolver e testar a eficácia de uma vacina bivalente inativada contra o vírus da raiva (RABV) e CDV a presente tese será apresentada na forma de dois artigos científicos. Ainda, um artigo de revisão sobre os modelos animais utilizados para obtenção de informações sobre o vírus do sarampo utilizando a infecção de CDV em furões e cães foi publicada e será apresentada na presente tese. No primeiro artigo, foi analisada a ocorrência de recombinação homóloga em genomas de CDV e detectou-se oito possíveis vírus recombinantes, incluindo um evento de recombinação entre uma cepa de campo e uma cepa vacinal atenuada, sugerindo que o uso de vacinação com vírus vivo atenuado pode influenciar a evolução do CDV. No segundo trabalho, uma vacina recombinante bivalente inativada baseada em RABV expressando as glicoproteínas do envelope do CDV, hemaglutinina e proteína de fusão, mostrou-se eficiente na proteção contra infecção por CDV em furões quando utilizado um protocolo prime/boost. Finalmente, foi publicada uma revisão de literatura sobre os modelos animais utilizados para obtenção de informações sobre a patogênese do vírus do sarampo utilizando a infecção com o vírus da cinomose.

Canine distemper virus (CDV) is an important pathogen of domestic dogs and wild carnivores. CDV infection is globally relevant and it is associated with high morbidity and mortality. In several countries, distemper is considered controlled by vaccination, however, in Brazil it is still endemic, mainly due to the large number of non-domiciliated animals. In addition, outbreaks in dogs and various species of wild animals occur frequently, decimating threatened populations. Live attenuated vaccines are safe for dogs, but their use is not advised in species that are highly susceptible to CDV infection. Also, reports of canine distemper in supposedly vaccinated dogs raise the hypothesis that commercially available vaccines may not be effective against some wild type strains. In order to investigate the mechanisms of CDV evolution and to develop and assess the efficacy of an inactivated bivalent vaccine against rabies virus and CDV, this thesis will be presented in…

Advisors/Committee Members: Canal, Cláudio Wageck.

Subjects/Keywords: Virologia veterinaria; Canine distemper virus; Vírus da cinomose canina; Homologous recombination; Virus da raiva; Vaccine; Rabies virus; Recombinação homóloga; Vacinas; Animal models; Modelos animais

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Budaszewski, R. d. F. (2017). Estudos sobre vacinologia e evolução do vírus da cinomose canina. (Thesis). Universidade do Rio Grande do Sul. Retrieved from http://hdl.handle.net/10183/163434

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Budaszewski, Renata da Fontoura. “Estudos sobre vacinologia e evolução do vírus da cinomose canina.” 2017. Thesis, Universidade do Rio Grande do Sul. Accessed March 04, 2021. http://hdl.handle.net/10183/163434.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Budaszewski, Renata da Fontoura. “Estudos sobre vacinologia e evolução do vírus da cinomose canina.” 2017. Web. 04 Mar 2021.

Vancouver:

Budaszewski RdF. Estudos sobre vacinologia e evolução do vírus da cinomose canina. [Internet] [Thesis]. Universidade do Rio Grande do Sul; 2017. [cited 2021 Mar 04]. Available from: http://hdl.handle.net/10183/163434.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Budaszewski RdF. Estudos sobre vacinologia e evolução do vírus da cinomose canina. [Thesis]. Universidade do Rio Grande do Sul; 2017. Available from: http://hdl.handle.net/10183/163434

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Edinburgh

12. Acosta-Jamett, Gerardo. Role of domestic dogs in diseases of significance to humans and wildlife health in central Chile.

Degree: PhD, 2010, University of Edinburgh

URL: http://hdl.handle.net/1842/4428

► The higher proximity among humans, domestic animals and wildlife favours disease spill-over both from wildlife to domestic animals and vice versa, which is a potential… (more)

▼ The higher proximity among humans, domestic animals and wildlife favours disease spill-over both from wildlife to domestic animals and vice versa, which is a potential risk for the extinction of wildlife populations and could be influencing the emergence and/or re-emergence of zoonotic diseases. The domestic dog (Canis familiaris) is the most abundant and widely distributed carnivore worldwide and is known to be carrying many infectious diseases. Among these diseases, domestic dogs are known to be source of canine distemper virus (CDV), canine parvovirus (CPV) and Echinococcus granulosus to wild carnivores and human being. Populations of domestic dogs inhabiting urban areas can be the source of infection of directly transmitted pathogens, since in these areas a high density of domestic dogs can facilitate the maintenance of these infections to both domestic and wild carnivore populations. In addition, the knowledge of the diseases present in the domestic dog populations in close proximity to wildlife is essential for conservation planning and for control of both zoonotic diseases and diseases of conservation concern. This thesis explores the effect of urbanization on the epidemiology of CDV, CPV, and E granulosus in domestic dogs and wild carnivores of the Coquimbo region of Chile as for example, chilla (L. griseus) and culpeo (L. culpaeus) foxes and assess the risk factors that could be facilitate disease transmission between canid inhabiting urban and rural areas. The first of the chapters containing original data, Chapter 3, describe the demography of dogs in the study area, indicating that urban sites have a greater population and a higher density of domestic dogs, a high growth rate and therefore a high turnover of susceptible than rural areas, which can be of relevance for the differences in diseases transmission patterns between these sites. Chapter 4 describe the degree of interaction between wild and domestic carnivores and its effect on interespecific disease transmission; indicating that in the study area there are many opportunities for domestic/wild carnivores interactions, as for example livestock predation by carnivores, by approaching to peridomestic environments, facilitating in this scenario the transmission of CDV, CPV and also E. granulosus by predating on livestock contaminated with cyst echinococcosis. Chapter 5 indicate that urban areas hold domestic dog populations with higher CDV seroprevalence than rural sites and probably these areas are the source of infection to rural sites. In contrast, a more stable CPV seroprevalence was found between urban and rural areas, indicating that possibly this pathogen follow an endemic state across the study area. Chapter 6 describe the factors for E. granulosus prevalence in domestic dogs, livestock and human being, suggesting that more cases of E. granulosus in livestock and in humans are found in provinces of the Coquimbo region with higher percentage of rural population; however, and unexpectedly, more cases of E. granulosus in domestic dogs were found…

Subjects/Keywords: 636.089; canine distemper virus; canine parvovirus; hydatid disease; domestic dogs; wild carnivores

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Acosta-Jamett, G. (2010). Role of domestic dogs in diseases of significance to humans and wildlife health in central Chile. (Doctoral Dissertation). University of Edinburgh. Retrieved from http://hdl.handle.net/1842/4428

Chicago Manual of Style (16^th Edition):

Acosta-Jamett, Gerardo. “Role of domestic dogs in diseases of significance to humans and wildlife health in central Chile.” 2010. Doctoral Dissertation, University of Edinburgh. Accessed March 04, 2021. http://hdl.handle.net/1842/4428.

MLA Handbook (7^th Edition):

Acosta-Jamett, Gerardo. “Role of domestic dogs in diseases of significance to humans and wildlife health in central Chile.” 2010. Web. 04 Mar 2021.

Vancouver:

Acosta-Jamett G. Role of domestic dogs in diseases of significance to humans and wildlife health in central Chile. [Internet] [Doctoral dissertation]. University of Edinburgh; 2010. [cited 2021 Mar 04]. Available from: http://hdl.handle.net/1842/4428.

Council of Science Editors:

Acosta-Jamett G. Role of domestic dogs in diseases of significance to humans and wildlife health in central Chile. [Doctoral Dissertation]. University of Edinburgh; 2010. Available from: http://hdl.handle.net/1842/4428

Freie Universität Berlin

13. Köhnke, Rebecca. Recombinant Canine Distemper Virus as a Possible Vector for the Delivery of Simian Immunodeficiency Virus Antigens.

Degree: 2018, Freie Universität Berlin

URL: http://dx.doi.org/10.17169/refubium-857

► Hundestaupevirus als möglicher Vektor für SIV-Antigene – Etablierung rekombinanter Vektoren mit und ohne SIVgag-Insert und Evaluierung dieser Vektoren auf klinische Sicherheit und Immunogenität im Frettchenmodell… (more)

▼ Hundestaupevirus als möglicher Vektor für SIV-Antigene – Etablierung rekombinanter Vektoren mit und ohne SIVgag-Insert und Evaluierung dieser Vektoren auf klinische Sicherheit und Immunogenität im Frettchenmodell Das Humane Immunodefizienz-Virus (HIV) und das durch die Infektion letztendlich verursachte erworbene Immundefizienzsyndrom (AIDS) werden oft als eine moderne Plage der Menschheit bezeichnet. Aufgrund der besonderen Biologie des HI-Virus kann mit medikamentöser Behandlung derzeit das Virus nicht eliminiert erden. Vorbeugende Maßnahmen haben zwar weltweit die Neuinfektionsrate vermindert, aber es wird davon ausgegangen, dass letztendlich nur ein Impfstoff für ein Ende des Ausbreitens der Epidemie sorgen kann. Um die Pathogenese, Behandlung und Prävention einer HIV-Infektion wissenschaftlich zu untersuchen, wird häufig auf das nicht humanpathogene Simian Immunodeficiency Virus (SIV) als Modellorganismus zurückgegriffen. Zahlreiche verschiedene Impfstoffansätze sind in der Entwicklung, wobei die Verwendung viraler Vektoren sich über die letzten Jahre als erfolgversprechend erwiesen hat. Speziell die Applikation solcher Vektoren über die Schleimhäute hat wiederholt zu der verstärkten Ausbildung mukosaler Immunantworten geführt und ist deshalb von Interesse. Ein geeigneter Vektor verfügt über ähnliche Charakteristiken wie das pathogene Virus, gegen das geimpft werden soll, vor allem in Bezug auf Zelltropismus und Ort der Virusreplikation im Körper. Dadurch werden die im Vektor inkorporierten Fremdantigene direkt an die während einer natürlichen Infektion relevanten anatomischen Strukturen geführt. Morbilliviren infizieren ihre natürlichen Wirte über die Schleimhäute. Daraufhin infiziert das Virus bevorzugt T-Zellen, vor allem im gastrointestinalen lymphatischen System, und verursacht so eine Immunsuppression. Im Rahmen dieser Arbeit wurde ein attenuiertes Hundestaupevirus als Vektor für SIV-Antigene evaluiert. Das Hundestaupevirus ist in vitro fähig Primatenzellen zu infizieren, aber nicht humanpathogen. Das Virus wurde als rekombinantes Virus aus Zellkultur isoliert und die Erbinformation für das SIV gag Protein in den Vektor integriert. Gag ist ein hoch immunogenes, wichtige virales Strukturprotein. Replikationsfähigkeit und Infektiosität der rekombinanten Vektoren in vitro sowie Präsenz der Gag-Sequenz wurden überprüft. Die rekombinanten Vektoren wurden dann auf intranasalem Wege an staupe-empfängliche Frettchen verabreicht. Der klinische Zustand der Frettchen und das Vorhandensein von Staupesymptomen wurden überprüft. Wiederholt wurden Blut- und Gewebeproben auf Virusgehalt und Hinweise auf Immunreaktionen untersucht. Das rekombinante Staupevirus mit SIV Gag-Insert hat sich in dieser Studie in einer hochempfindlichen Spezies als klinisch unbedenklich, aber dennoch replikationsfähig erwiesen. Blut- und Gewebeproben weisen Anzeichen humoraler und zellulärer Immunreaktionen sowohl auf den Vektor selbst als auch auf das Insert auf. Advisors/Committee Members: female (gender), Gruber, Achim (firstReferee), Hartmann, Susanne (furtherReferee), Osterrieder, Klaus (furtherReferee).

Subjects/Keywords: Ferrets; Animal Models; Canine Distemper Virus; Genetic Vectors; Gag Protein; Epidemiology; Simian Immunodeficiency Virus(MeSH); 600 Technology, Medicine, Applied sciences::630 Agriculture, Veterinary medicine::630 Agriculture, Veterinary medicine

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Köhnke, R. (2018). Recombinant Canine Distemper Virus as a Possible Vector for the Delivery of Simian Immunodeficiency Virus Antigens. (Thesis). Freie Universität Berlin. Retrieved from http://dx.doi.org/10.17169/refubium-857

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Köhnke, Rebecca. “Recombinant Canine Distemper Virus as a Possible Vector for the Delivery of Simian Immunodeficiency Virus Antigens.” 2018. Thesis, Freie Universität Berlin. Accessed March 04, 2021. http://dx.doi.org/10.17169/refubium-857.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Köhnke, Rebecca. “Recombinant Canine Distemper Virus as a Possible Vector for the Delivery of Simian Immunodeficiency Virus Antigens.” 2018. Web. 04 Mar 2021.

Vancouver:

Köhnke R. Recombinant Canine Distemper Virus as a Possible Vector for the Delivery of Simian Immunodeficiency Virus Antigens. [Internet] [Thesis]. Freie Universität Berlin; 2018. [cited 2021 Mar 04]. Available from: http://dx.doi.org/10.17169/refubium-857.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Köhnke R. Recombinant Canine Distemper Virus as a Possible Vector for the Delivery of Simian Immunodeficiency Virus Antigens. [Thesis]. Freie Universität Berlin; 2018. Available from: http://dx.doi.org/10.17169/refubium-857

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

14. Chaudhary, Vratika. Threats of Disease Spillover from Domestic Dogs to Wild Carnivores in the Kanha Tiger Reserve, India.

Degree: MS, Biological Sciences, 2016, Clemson University

URL: https://tigerprints.clemson.edu/all_theses/2352

► Many mammalian carnivore species persist in small, isolated populations as a result of habitat destruction, fragmentation, poaching, and human conflict. Their small numbers, limited genetic… (more)

▼ Many mammalian carnivore species persist in small, isolated populations as a result of habitat destruction, fragmentation, poaching, and human conflict. Their small numbers, limited genetic variability, and increased exposure to domestic animals such as dogs place them at risk of further losses due to infectious diseases. In India, dogs ranging from domestic to feral are associated with villages in and around protected areas, and may serve as reservoirs and vectors of pathogens to the carnivores within. Indiaâ€™s Kanha Tiger Reserve (KTR) is home to a number of threatened and endangered mammalian carnivores including tigers (Panthera tigris), leopards (Panthera pardus), wolves (Canis lupus), and dhole (Cuon alpinus). It also contains hundreds of small villages with associated dog populations, and my goal was to determine whether these dogs pose a disease threat to KTR's wild carnivores. In the summer of 2014 and again in the winter of 2015 I estimated the density of dogs in villages of varying sizes and distances from KTR's core zone, and the exposure of these dogs to four pathogens that could threaten wild carnivores: rabies, canine parvovirus (CPV), canine distemper (CDV), and canine adenovirus (CAV). Dog population densities ranged from 3.7 to 23.7/km2 (14 to 45 dogs/village), and showed no systematic variation with village area or human population size. These dog populations grew in all villages between the summer of 2014 and winter of 2015, primarily through reproduction. No dog tested positive for rabies but I found high levels of seroprevalence to the other three pathogens: CPV (83.6% in summer 2014, 68.4% in winter 2015), CDV (50.7% in summer 2014, 30.4% in winter 2015) and CAV (41.8% in summer 2014, 30.9% in winter 2015). The declines in seroprevalence between summer and winter were primarily due to births in the population, of animals not exposed to the viruses. I opportunistically documented interactions between the dogs and wild carnivores that might allow disease transmission. I measured these interactions as the presence of wild carnivores in surveyed villages. In this study I document the existence of a large population of unvaccinated dogs in and around KTR, with high levels of seroprevalence to pathogens with broad host ranges. These dogs also have frequent contact with wild carnivores. I conclude that these dogs pose a high risk of disease spillover to wild carnivores in the region. I also tested for CPV and CDV in wild carnivore samples obtained from the KTR Forest Department from 2010 to 2015. While one tiger blood sample was seropositive for CPV antibodies, the reverse transcriptase polymerase chain reaction found no evidence of CPV in tissue samples from five tigers, one leopard and one palm civet (Paradoxurus hermaphroditus), and no CPV or CDV in the three blood samples of tigers. Despite these results, I argue for continued surveillance in KTR, given the ubiquity of village dogs in the area with high seroprevalence of CDV and CPV and the contact between dogs and… Advisors/Committee Members: Dr. David W. Tonkyn, Committee Chair, Dr. Charles Rice, Dr. A. B. Shrivastav.

Subjects/Keywords: Canine adeno virus; Canine distemper virus; Canine parvovirus; Infectious disease; Leopard; Tiger

…Helden & Millar, 2014), canine distemper virus (CDV) in Amur tigers (… …carried by dogs and affect many carnivore species worldwide are the rabies virus, canine… …parvovirus (CPV), CDV (Pedersen et al., 2007), and canine adeno virus (CAV… …1996), and rabies virus in Ethiopian wolves (Canis simensis: Laurenson et al., 1998… …ways. Rabies virus is shed from the salivary glands and usually transmitted when an infected…

7 more images…

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Chaudhary, V. (2016). Threats of Disease Spillover from Domestic Dogs to Wild Carnivores in the Kanha Tiger Reserve, India. (Masters Thesis). Clemson University. Retrieved from https://tigerprints.clemson.edu/all_theses/2352

Chicago Manual of Style (16^th Edition):

Chaudhary, Vratika. “Threats of Disease Spillover from Domestic Dogs to Wild Carnivores in the Kanha Tiger Reserve, India.” 2016. Masters Thesis, Clemson University. Accessed March 04, 2021. https://tigerprints.clemson.edu/all_theses/2352.

MLA Handbook (7^th Edition):

Chaudhary, Vratika. “Threats of Disease Spillover from Domestic Dogs to Wild Carnivores in the Kanha Tiger Reserve, India.” 2016. Web. 04 Mar 2021.

Vancouver:

Chaudhary V. Threats of Disease Spillover from Domestic Dogs to Wild Carnivores in the Kanha Tiger Reserve, India. [Internet] [Masters thesis]. Clemson University; 2016. [cited 2021 Mar 04]. Available from: https://tigerprints.clemson.edu/all_theses/2352.

Council of Science Editors:

Chaudhary V. Threats of Disease Spillover from Domestic Dogs to Wild Carnivores in the Kanha Tiger Reserve, India. [Masters Thesis]. Clemson University; 2016. Available from: https://tigerprints.clemson.edu/all_theses/2352

Universidade do Rio Grande do Sul

15. Sonne, Luciana. Achados patológicos e imunoistoquímicos de cães infectados pelo vírus da cinomose canina.

Degree: 2008, Universidade do Rio Grande do Sul

URL: http://hdl.handle.net/10183/13843

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A cinomose canina é uma doença viral e afeta principalmente os sistemas respiratório, gastrintestinal e nervoso. O presente trabalho analisou 54 cães com cinomose de… (more)

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A cinomose canina é uma doença viral e afeta principalmente os sistemas respiratório, gastrintestinal e nervoso. O presente trabalho analisou 54 cães com cinomose de um total de 760 cães necropsiados no período de julho de 2006 a outubro de 2007. As lesões macroscópicas observadas eram caracterizadas por secreção ocular e nasal mucopurulentas, hiperqueratose dos coxins digitais, pulmões de coloração avermelhada e não colabados, atrofia do timo, conteúdo intestinal diarréico e evidenciação das placas de Peyer. Os achados microscópicos caracterizavam-se principalmente por pneumonia intersticial, rarefação linfóide, desmielinização da substância branca, manguitos perivasculares e corpúsculos de inclusão viral na mucosa do estômago, epitélios da bexiga, brônquios e bronquíolos, pelve renal, coxins digitais, pálpebra e orelha, no sistema nervoso central (principalmente em astrócitos) e em células mononucleares dos linfonodos, baço e tonsilas. O teste de imunoistoquímica foi positivo em 94,4% dos casos analisados. Os tecidos foram marcados pela técnica imunoistoquímica utilizando o anticorpo monoclonal anti-cinomose canina (VMRD) na diluição de 1:400. O coxim digital se apresentou como o órgão com o maior número de casos marcados positivamente (67,4%), seguido pelo estômago com 62,7%. A utilização da imunoistoquímica auxiliou na identificação do antígeno viral em diferentes tecidos e foi importante como diagnóstico complementar da cinomose canina.

Canine distemper is a viral disease that affects mainly, respiratory, gastrointestinal and nervous system. The present study analyzed 54 dogs with canine distemper from total of 760 necropsies done in dogs between July 2006 to October 2007. The macroscopic lesion were characterized by mucopurulent oculonasal discharge, hyperkeratosis of footpads, red and not collapsed lungs, thymic atrophy, watery intestinal, hyperemia and Peyer’s patches enlarged. The microscopic findings were characterized by interstitial pneumonia, lymphoid depletion, white matter demylization, perivascular cuffs and viral inclusion bodies located in stomach mucosa, bladder, bronchial, renal pelvis, footpads, eyelid, skin of the ear epithelium, central nervosus system (mainly in astrocytes) and mononuclear infiltrates in lymph nodes, spleen, and tonsils. The immunohistochemistry test was positive in 94,4% of analyzed cases. Tissues were strained by an immunohistochemical procedure with mouse monoclonal anti-cinomose (VMRD) diluted 1:400. The footpads was the best tissue with majority of positive marked cases (67,4%), followed by stomach with 62,7%. This observation suggests that the immunohistochemistry technique aided to identify distemper virus antigens in different tissue making it an important test for complementary diagnostic of canine distemper.

Advisors/Committee Members: Carissimi, Andre Silva.

Subjects/Keywords: Patologia veterinaria : Caes; Canine distemper; Dogs; Vírus da cinomose canina; Imunohistoquimica : Virus; Immunohistochemistry

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Sonne, L. (2008). Achados patológicos e imunoistoquímicos de cães infectados pelo vírus da cinomose canina. (Thesis). Universidade do Rio Grande do Sul. Retrieved from http://hdl.handle.net/10183/13843

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Sonne, Luciana. “Achados patológicos e imunoistoquímicos de cães infectados pelo vírus da cinomose canina.” 2008. Thesis, Universidade do Rio Grande do Sul. Accessed March 04, 2021. http://hdl.handle.net/10183/13843.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Sonne, Luciana. “Achados patológicos e imunoistoquímicos de cães infectados pelo vírus da cinomose canina.” 2008. Web. 04 Mar 2021.

Vancouver:

Sonne L. Achados patológicos e imunoistoquímicos de cães infectados pelo vírus da cinomose canina. [Internet] [Thesis]. Universidade do Rio Grande do Sul; 2008. [cited 2021 Mar 04]. Available from: http://hdl.handle.net/10183/13843.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Sonne L. Achados patológicos e imunoistoquímicos de cães infectados pelo vírus da cinomose canina. [Thesis]. Universidade do Rio Grande do Sul; 2008. Available from: http://hdl.handle.net/10183/13843

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Freie Universität Berlin

16. Rentería-Solís, Zaida Melina. Vorkommenden Krankheitsfälle bei frei lebenden Waschbären (Procyon lotor) aus ruralen und urbanen Populationen in Nordostdeutschland.

Degree: 2017, Freie Universität Berlin

URL: http://dx.doi.org/10.17169/refubium-5943

► Seit seiner ersten, 1934 erfolgten, Einbürgerung ist der Nordamerikanische Waschbär (Proyon lotor) eine invasive Tierart in Deutschland. Waschbären sind in Deutschland weit verbreitet, können aber… (more)

▼ Seit seiner ersten, 1934 erfolgten, Einbürgerung ist der Nordamerikanische Waschbär (Proyon lotor) eine invasive Tierart in Deutschland. Waschbären sind in Deutschland weit verbreitet, können aber in zwei Hauptpopulationen differenziert werden: Eine im Zentrum (Hessen), eine andere im nordöstlichen Landesteil (Mecklenburg-Vorpommern, Brandenburg). In Nordamerika gilt der Waschbär als bekannter Überträger von Infektionserregern wie Tollwut, Staupe oder dem zoonotischen Nematoden Baylisascaris procyonis. Aber trotz ihrer 70 Jahre währenden, erfolgreichen Einbürgerung gibt es wenig Kenntnis zu Infektionskrankheiten bei Waschbären in Deutschland. Um zu untersuchen, welche Krankheiten oder Krankheitserreger bei diesen Tieren vorkommen, wurden zwei Teilpopulationen in Nordostdeutschland ausgewählt: eine in einem ländlichen Waldgebiet (Müritz Nationalpark (MNP), Mecklenburg-Vorpommern), ein urbane im Großraum Berlin. Insgesamt wurden 240 Verkehrsopfer, jagdlich erlegte oder eingeschläferte Waschbären untersucht: 100 aus dem MNP (2007 bis 2011) und 140 aus Berlin (2011-2013). Tierkörpersektionen, histologische, mikrobiologische und molekularbiologische Untersuchungen von ausgewählten Erregern wurden mit diesen Tieren durchgeführt. Die Ergebnisse sind in vier wissenschaftlichen Artikeln veröffentlicht: Artikel I: In vorangegangenen Studien histologisch entdeckte Parasitenzysten im Zungengewebe von Waschbären wurden untersucht und ihre Artzugehörigkeit identifiziert. Mesozerkarien konnten aus neun Tieren vom MNP und einem Tier aus Berlin isoliert und mittels PCR als Alaria alata in identifiziert werden. In histologischen Untersuchungen wurden A. alata Mesozerkarien nur in Zungengewebe detektiert, jedoch nicht in anderen Organen. Das deutet darauf hin, dass Waschbären für diesen Trematoden als paratenische Wirte auftreten. Die höhere Anzahl positiver A. alata Fälle im MNP im Vergleich zu Berlin läßt sich durch Unterschiede in der Nahrungszusammensetzung erklären, da den Waschbären im MNP häufiger Zwischenwirte von A. alata, wie Amphibien, zur Verfügung stehen als den urbanen Waschbären. Es konnte hier gezeigt werden, dass eine neueingebürgerte Art wie der Waschbär das Wirtsspektrum endemischer Parasiten erweitern kann. Artikel II: Der zweite Artikel aus diesem Projekt beschreibt Sarcoptesräude in urbanen Waschbären mit drei Fällen aus Berlin und zwei Fällen aus Kassel. Makroskopische Hautläsionen, histo-pathologische Befunde und die Morphologie der Milben werden beschrieben. Um den möglichen Ursprung der Infektionen zu finden, wurden neun Mikrosatellitenmarker für die Genotypisierung der von Waschbären isolierten Milben verwendet, um sie mit S. scabiei von Füchsen, Wildschweinen und Gämsen zu vergleichen. Die Milben der Waschbären lagen in einem Cluster mit S. scabiei von Füchsen, was für einem Infektionsursprung aus Füchsen spricht. Diese Ergebnisse deuten auf eine zwischenartliche Übertragung von S. scabiei zwischen urbanen Füchsen und Waschbären hin. Artikel III: Der erste große Staupeausbruch von Waschbären in Deutschland… Advisors/Committee Members: w (gender), Univ.-Prof. Dr. Alex Greenwood (firstReferee), PD Dr. Kerstin Müller (furtherReferee), Prof. Dr. Katharina Riehn (furtherReferee).

Subjects/Keywords: Procyon lotor; Alaria alata; Sarcoptes scabiei; animal parasitic nematodes; Canine distemper virus; Mecklenburg-Pomerania; 600 Technik, Medizin, angewandte Wissenschaften::630 Landwirtschaft::630 Landwirtschaft und verwandte Bereiche

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Rentería-Solís, Z. M. (2017). Vorkommenden Krankheitsfälle bei frei lebenden Waschbären (Procyon lotor) aus ruralen und urbanen Populationen in Nordostdeutschland. (Thesis). Freie Universität Berlin. Retrieved from http://dx.doi.org/10.17169/refubium-5943

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Rentería-Solís, Zaida Melina. “Vorkommenden Krankheitsfälle bei frei lebenden Waschbären (Procyon lotor) aus ruralen und urbanen Populationen in Nordostdeutschland.” 2017. Thesis, Freie Universität Berlin. Accessed March 04, 2021. http://dx.doi.org/10.17169/refubium-5943.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Rentería-Solís, Zaida Melina. “Vorkommenden Krankheitsfälle bei frei lebenden Waschbären (Procyon lotor) aus ruralen und urbanen Populationen in Nordostdeutschland.” 2017. Web. 04 Mar 2021.

Vancouver:

Rentería-Solís ZM. Vorkommenden Krankheitsfälle bei frei lebenden Waschbären (Procyon lotor) aus ruralen und urbanen Populationen in Nordostdeutschland. [Internet] [Thesis]. Freie Universität Berlin; 2017. [cited 2021 Mar 04]. Available from: http://dx.doi.org/10.17169/refubium-5943.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Rentería-Solís ZM. Vorkommenden Krankheitsfälle bei frei lebenden Waschbären (Procyon lotor) aus ruralen und urbanen Populationen in Nordostdeutschland. [Thesis]. Freie Universität Berlin; 2017. Available from: http://dx.doi.org/10.17169/refubium-5943

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Pretoria

17. Woma, Timothy Yusufu. The isolation and genetic characterization of canine distemper viruses from domestic dogs (Canis familiaris) in South Africa.

Degree: Veterinary Tropical Diseases, 2008, University of Pretoria

URL: http://hdl.handle.net/2263/26280

► Studies comparing canine distemper virus (CDV) strains from Africa with that of previously described lineages have been hampered due to a lack of field strains… (more)

▼ Studies comparing canine distemper virus (CDV) strains from Africa with that of previously described lineages have been hampered due to a lack of field strains for in vitro experiments. There are no reports of CDV isolations in southern Africa, and although CDV is said to have geographically distinct lineages, molecular information of African strains has not yet been documented. Clinical specimens consisting of whole blood, spleen, lungs, brain and cerebrospinal fluid from dogs with clinical signs suggestive of distemper were obtained from private veterinary practices and diagnostic laboratories in Gauteng province, South Africa. One hundred and sixty two specimens from 124 dogs were inoculated into Vero cells expressing canine signalling lymphocyte activation molecule (Vero.DogSLAM). Cytopathic effects (CPE) in the form of syncytia formation and cell necrosis were observed in 33 (20.4%) specimens within 24 hours of inoculation and the presence of CDV was confirmed with the aid of the direct fluorescent antibody test and electronmicroscopy (EM). Viruses isolated in cell cultures were subjected to reverse transcription – polymerase chain reaction (RT-PCR), and the complete H gene was sequenced and phylogenetically analysed with other strains from GenBank. The animals all displayed the catarrhal, systemic, or nervous signs of the disease. Four of the dogs positive for CDV by viral isolation had a history of prior vaccinations to canine distemper. Seventy three percent of all positive dogs were less than 12 months old. There was no breed or sex predisposition to CDV infection in domestic dogs. Phylogenetic comparisons of the complete H gene of CDV isolates from different parts of the world (available in GenBank) with wild-type South African isolates revealed nine clades. All South African isolates form a separate African clade of their own and thus are clearly separated from the American, European, Asian, Arctic and vaccine virus clades. It is likely that only the ‘African lineage’ of CDV may be circulating in South Africa currently, and the viruses isolated from dogs vaccinated against CDV are not the result of reversion to virulence of vaccine strains, but infection with wild-type strains. Copyright Advisors/Committee Members: Van Vuuren, Moritz (advisor).

Subjects/Keywords: Canine distemper virus; Domestic dogs; South Africa; UCTD; Dogs – Diseases

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Woma, T. Y. (2008). The isolation and genetic characterization of canine distemper viruses from domestic dogs (Canis familiaris) in South Africa. (Masters Thesis). University of Pretoria. Retrieved from http://hdl.handle.net/2263/26280

Chicago Manual of Style (16^th Edition):

Woma, Timothy Yusufu. “The isolation and genetic characterization of canine distemper viruses from domestic dogs (Canis familiaris) in South Africa.” 2008. Masters Thesis, University of Pretoria. Accessed March 04, 2021. http://hdl.handle.net/2263/26280.

MLA Handbook (7^th Edition):

Woma, Timothy Yusufu. “The isolation and genetic characterization of canine distemper viruses from domestic dogs (Canis familiaris) in South Africa.” 2008. Web. 04 Mar 2021.

Vancouver:

Woma TY. The isolation and genetic characterization of canine distemper viruses from domestic dogs (Canis familiaris) in South Africa. [Internet] [Masters thesis]. University of Pretoria; 2008. [cited 2021 Mar 04]. Available from: http://hdl.handle.net/2263/26280.

Council of Science Editors:

Woma TY. The isolation and genetic characterization of canine distemper viruses from domestic dogs (Canis familiaris) in South Africa. [Masters Thesis]. University of Pretoria; 2008. Available from: http://hdl.handle.net/2263/26280

Universidade do Rio Grande do Sul

18. Hartmann, Tamahine Larronda Schmidt. Anticorpos neutralizantes contra os vírus da cinomose e parainfluenza caninos em cães e felinos silvestres em cativeiro.

Degree: 2006, Universidade do Rio Grande do Sul

URL: http://hdl.handle.net/10183/8197

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O vírus da cinomose canina (CDV) e o vírus parainfluenza canino (CPIV) afetam uma ampla variedade de hospedeiros e encontram-se distribuídos mundialmente. O CDV é… (more)

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O vírus da cinomose canina (CDV) e o vírus parainfluenza canino (CPIV) afetam uma ampla variedade de hospedeiros e encontram-se distribuídos mundialmente. O CDV é considerado um dos mais importantes agentes infecciosos dentro das populações caninas. Este vírus é o agente causal da cinomose, uma doença potencialmente letal em membros das famílias Canidae, Mustelidae e Procionidae, sendo recentemente detectado como causa de morbidade e mortalidade em carnívoros aquáticos e grandes felinos. O CPIV, por sua vez, é altamente contagioso entre cães, podendo infectar roedores e gatos em infecções experimentais. Geralmente, o CPIV produz uma traqueobronquite aguda auto-limitante, porém pode atuar sinergicamente com outros agentes infecciosos, como o CDV, causando sinais clínicos mais graves. Como em nosso meio são escassas as informações sobre estes vírus, o presente estudo visou aprofundar os conhecimentos sobre a prevalência de CDV e CPIV em cães e felinos silvestres mantidos em cativeiro. Para tanto, soros destes animais foram testados em busca de anticorpos neutralizantes contra amostras padrão do CDV (Rockborn e Snyder Hill) e do CPIV (V660). Inicialmente, foram testados soros de 173 cães de rua mantidos em canis municipais em Novo Hamburgo e Porto Alegre, RS. A prevalência de anticorpos neutralizantes anti-CDV frente às amostras de vírus da cinomose Rockborn e Snyder Hill, foi de 9,3 % e 4,1 %, respectivamente. Somente dois cães apresentaram títulos de anticorpos considerados protetores contra CDV Rockborn (igual ou maior que 100) e nenhum soro apresentou título de anticorpos neutralizantes considerado protetor para a amostra Snyder Hill (igual ou maior que 100). Contra a amostra de parainfluenza canino V660, a prevalência de anticorpos neutralizantes encontrada foi de 51,4 %. Conclui-se, portanto, que a população de cães de rua amostrada apresenta poucos indícios de contato prévio com CDV, sugerindo grande susceptibilidade à cinomose. Por outro lado, o CPIV parece circular amplamente nesta população. Na segunda parte do presente estudo, como no Brasil não existem relatos sobre CDV e CPIV em felinos silvestres, buscou-se verificar a possibilidade da ocorrência dessas infecções em felinos silvestres brasileiros. Para tanto, foram testados soros de 84 felinos silvestres de seis diferentes espécies nativas do Brasil (Leopardus tigrinus, Puma concolor, Leopardus wiedii, Herpailurus yaguarondi, Panthera onca), todos mantidos em cativeiro em criatórios de distintas regiões do País. Todos os felinos amostrados apresentaram-se soronegativos frente às amostras de CDV e CPIV utilizadas. Estes resultados indicam que CDV e CPIV parecem não circular nas populações de felinos silvestres amostradas.

Canine distemper virus (CDV) and canine parainfluenza virus (CPIV) infect a great variety of hosts ranges and are distributed worldwide. CDV is one of the most important infectious agents in dogs. This virus may cause potentially lethal disease among members of the Canidae, Mustelidae and Procionidae families. It has also caused…

Advisors/Committee Members: Roehe, Paulo Michel.

Subjects/Keywords: Canine distemper virus; Virologia veterinaria; Canine parainfluenza virus; Cinomose; Dogs; Imunologia veterinaria : Caes; Wild felids; Imunologia : Anticorpos; Sero neutralization; Prevalence

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Hartmann, T. L. S. (2006). Anticorpos neutralizantes contra os vírus da cinomose e parainfluenza caninos em cães e felinos silvestres em cativeiro. (Thesis). Universidade do Rio Grande do Sul. Retrieved from http://hdl.handle.net/10183/8197

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Hartmann, Tamahine Larronda Schmidt. “Anticorpos neutralizantes contra os vírus da cinomose e parainfluenza caninos em cães e felinos silvestres em cativeiro.” 2006. Thesis, Universidade do Rio Grande do Sul. Accessed March 04, 2021. http://hdl.handle.net/10183/8197.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Hartmann, Tamahine Larronda Schmidt. “Anticorpos neutralizantes contra os vírus da cinomose e parainfluenza caninos em cães e felinos silvestres em cativeiro.” 2006. Web. 04 Mar 2021.

Vancouver:

Hartmann TLS. Anticorpos neutralizantes contra os vírus da cinomose e parainfluenza caninos em cães e felinos silvestres em cativeiro. [Internet] [Thesis]. Universidade do Rio Grande do Sul; 2006. [cited 2021 Mar 04]. Available from: http://hdl.handle.net/10183/8197.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Hartmann TLS. Anticorpos neutralizantes contra os vírus da cinomose e parainfluenza caninos em cães e felinos silvestres em cativeiro. [Thesis]. Universidade do Rio Grande do Sul; 2006. Available from: http://hdl.handle.net/10183/8197

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Freie Universität Berlin

19. Günther-Weigl, Astrid. Humorale Immunantwort bei Europäischen Fischottern (Lutra lutra), Asiatischen Kurzkrallenottern (Aonyx cinereus) und Nordamerikanischen Fischottern (Lontra canadensis) nach Impfung mit unterschiedlichen Staupe Impfstoffen.

Degree: 2009, Freie Universität Berlin

URL: http://dx.doi.org/10.17169/refubium-11518

► Staupe, eine hochinfektiöse, systemische Viruserkrankung der Hunde und anderer Karnivoren, wird als die bedrohlichste Infektionskrankheit der Marderartigen betrachtet. In dieser Arbeit wurde die Sicherheit und… (more)

▼ Staupe, eine hochinfektiöse, systemische Viruserkrankung der Hunde und anderer Karnivoren, wird als die bedrohlichste Infektionskrankheit der Marderartigen betrachtet. In dieser Arbeit wurde die Sicherheit und Wirksamkeit der in Europa verfügbaren Staupeimpfstoffe bei Europäischen Fischottern (Lutra lutra), Asiatischen Kurzkrallenottern (Aonyx cinereus) und ansatzweise bei Nordamerikanischen Fischottern (Lontra canadensis) ermittelt. Zwei Methoden zur Antikörperbestimmung wurden verglichen. Der Referenzstandard zum Antikörpernachweis gegen Morbilliviren ist der Neutralisationstest (NT). Dieser ist zeitaufwendig und teuer. Ein kostengünstiger und schnell durchführbarer ELISA wäre sehr hilfreich. Siebzig Otter, aus 19 verschiedenen Zoos und Tierparks in Deutschland und den Niederlanden, beiderlei Geschlechts und im Alter zwischen 8 Wochen und 17 Jahren wurden geimpft. Zwei Studien wurden durchgeführt. In Studie 1 wurden bisher ungeimpfte Europäische Fischotter (n=27), Asiatische Kurzkrallenotter (n=28) und Nordamerikanische Fischotter (n=4) entweder mit inaktiviertem Staupeimpfstoff, mit CDV-ISCOM Impfstoff oder mit einem von drei verschiedenen Staupe Lebendimpfstoffen geimpft. In Studie 2 wurden die Antikörper (AK) Titer Europäischer Fischotter (n=11), die bisher regelmäßig gegen Staupe geimpft wurden, vor und nach einer Booster Impfung bestimmt. Folgende Ergebnisse wurden ermittelt: Bei keinem der Otter wurden klinische Symptome einer Staupe Erkrankung beobachtet. Die Immunantwort auf inaktivierten Staupeimpfstoff war schwach. CDV-ISCOM Impfstoff führte bei allen Tieren zu einer humoralen Immunantwort, hohe AK- Titer wurden jedoch nur im ELISA gemessen. Die Immunantwort auf Lebendimpfoff zeigte bei Europäischen Fischottern eine Abhängigkeit vom Impfstamm. Alter, Geschlecht, Tierart und Gewicht hatten keinen Einfluss auf die Immunantwort nach Impfung mit Staupe Lebendimpfstoff. Die drei Impfstofftypen (inaktiviert, ISCOM, lebend) zeigten einen signifikanten Unterschied in der Wirksamkeit, wobei Staupe Lebendimpfstoffe vom Onderstepoort Typ sich als am wirksamsten erwiesen. Zwischen Europäischen Fischottern und Asiatischen Kurzkrallenottern gab es keinen Unterschied in der Höhe der neutralisierenden AK-Titer nach zwei Impfdosen. Der Zusammenhang zwischen den zwei Nachweismethoden war nicht sehr stark. Booster Impfung bei Europäischen Fischottern mit Lebendimpfstoff (Onderstepoort Typ) induzierte einen signifikanten Anstieg der neutralisierenden AK, die bis Tag 365 nach Impfung auf einem angemessenen Level blieben. Die Ergebnisse führten zu folgenden Schlussfolgerungen: Der Einsatz der formalin-inaktivierten Staupe Vakzine mit Al(OH)3 als Adjuvant ist bei den getesteten Fischotterarten nicht sinnvoll. Staupe Lebendimpfstoffe vom Onderstepoort Typ sind wirksam bei Europäischen Fischottern und Asiatischen Kurzkrallenottern und scheinen bei diesen Arten sicher zu sein. Der experimentelle CDV-ISCOM Impfstoff ist sicher und wahrscheinlich eine wirksame Alternative. Der in dieser Studie eingesetzte ELISA ist einsetzbar für… Advisors/Committee Members: [email protected] (contact), w (gender), Univ.-Prof. Dr. Heribert Hofer (firstReferee), Prof. Dr. Klaus Eulenberger, (furtherReferee), Univ.-Prof. Klaus Osterrieder (furtherReferee).

Subjects/Keywords: Aonyx cinereus; canine distemper virus; immune response; Lontra canadensis; Lutra lutra; otters; vaccination; 600 Technik, Medizin, angewandte Wissenschaften::630 Landwirtschaft

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Günther-Weigl, A. (2009). Humorale Immunantwort bei Europäischen Fischottern (Lutra lutra), Asiatischen Kurzkrallenottern (Aonyx cinereus) und Nordamerikanischen Fischottern (Lontra canadensis) nach Impfung mit unterschiedlichen Staupe Impfstoffen. (Thesis). Freie Universität Berlin. Retrieved from http://dx.doi.org/10.17169/refubium-11518

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Günther-Weigl, Astrid. “Humorale Immunantwort bei Europäischen Fischottern (Lutra lutra), Asiatischen Kurzkrallenottern (Aonyx cinereus) und Nordamerikanischen Fischottern (Lontra canadensis) nach Impfung mit unterschiedlichen Staupe Impfstoffen.” 2009. Thesis, Freie Universität Berlin. Accessed March 04, 2021. http://dx.doi.org/10.17169/refubium-11518.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Günther-Weigl, Astrid. “Humorale Immunantwort bei Europäischen Fischottern (Lutra lutra), Asiatischen Kurzkrallenottern (Aonyx cinereus) und Nordamerikanischen Fischottern (Lontra canadensis) nach Impfung mit unterschiedlichen Staupe Impfstoffen.” 2009. Web. 04 Mar 2021.

Vancouver:

Günther-Weigl A. Humorale Immunantwort bei Europäischen Fischottern (Lutra lutra), Asiatischen Kurzkrallenottern (Aonyx cinereus) und Nordamerikanischen Fischottern (Lontra canadensis) nach Impfung mit unterschiedlichen Staupe Impfstoffen. [Internet] [Thesis]. Freie Universität Berlin; 2009. [cited 2021 Mar 04]. Available from: http://dx.doi.org/10.17169/refubium-11518.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Günther-Weigl A. Humorale Immunantwort bei Europäischen Fischottern (Lutra lutra), Asiatischen Kurzkrallenottern (Aonyx cinereus) und Nordamerikanischen Fischottern (Lontra canadensis) nach Impfung mit unterschiedlichen Staupe Impfstoffen. [Thesis]. Freie Universität Berlin; 2009. Available from: http://dx.doi.org/10.17169/refubium-11518

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Minnesota

20. Craft, Meggan E. Predicting disease dynamics in African lion populations.

Degree: Ecology, Evolution and Behavior, 2008, University of Minnesota

URL: http://purl.umn.edu/46993

► In 1994, one-third of Serengeti lions died from canine distemper virus (CDV). I estimated the epidemiological network structure of the Serengeti lion population using long-term… (more)

▼ In 1994, one-third of Serengeti lions died from canine distemper virus (CDV). I estimated the epidemiological network structure of the Serengeti lion population using long-term data. I found that the lion population is a mix of local pride-to-pride contacts (driven by territory adjacencies) and transient nomad-to-pride contacts (driven by gamma variance process). When canine distemper virus (CDV) was introduced into the network, I found that although nomads are numerous, travel long distances, and are likely candidates to be considered "superconnectors" (connecting distant parts of a network), their impacts on CDV disease dynamics were surprisingly low. Analysis of the data-driven, Levins-type network model demonstrates that the epidemic probably was not propagated solely by within-species transmission but rather involved multiple introductions from other carnivore species, such as jackals and hyenas. The social network model further suggests that the epidemiological observations from the 2000 km2 Serengeti study area may not have reflected the larger-scale dynamics because the sample was (1) located at the periphery of the pride-pride contact network and (2) confined to a small region relative to the scale of the ecosystem. If lions could not produce the observed CDV outbreak, and other wild carnivores were repeatedly involved in transmission to the lion population, could a multi-host spatial model account for the patchy pattern of CDV spread seen in lions in 1994? A stochastic susceptible-infected-recovered model was constructed which allowed transmission between a highly territorial species, like lions, and 1-2 more gregarious hosts, such as hyenas and jackals. When other gregarious species were coupled with lions with low interspecific contact rates, the erratic patterns of CDV spatial spread were similar to those seen in lions in 1994. The results of both the network and the multi-host models suggest that lions are a non-maintenance population for canine distemper virus, and more broadly address issues of spatial disease ecology and multi-host pathogens in complex ecosystems.

Subjects/Keywords: African Lion; Canine Distemper Virus; Disease Transmission; Multihost Model; Network Model; Social Structure; Ecology, Evolution and Behavior

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APA (6^th Edition):

Craft, M. E. (2008). Predicting disease dynamics in African lion populations. (Thesis). University of Minnesota. Retrieved from http://purl.umn.edu/46993

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Craft, Meggan E. “Predicting disease dynamics in African lion populations.” 2008. Thesis, University of Minnesota. Accessed March 04, 2021. http://purl.umn.edu/46993.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Craft, Meggan E. “Predicting disease dynamics in African lion populations.” 2008. Web. 04 Mar 2021.

Vancouver:

Craft ME. Predicting disease dynamics in African lion populations. [Internet] [Thesis]. University of Minnesota; 2008. [cited 2021 Mar 04]. Available from: http://purl.umn.edu/46993.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Craft ME. Predicting disease dynamics in African lion populations. [Thesis]. University of Minnesota; 2008. Available from: http://purl.umn.edu/46993

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

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