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Texas A&M University
1.
Gorde, Harshal Wasudeo.
Multispectral polarimetric sensor for glucose monitoring utilizing a digital closed-loop control system.
Degree: MS, biomedical engineering, 2012, Texas A&M University
URL: http://hdl.handle.net/1969.1/ETD-TAMU-1998-THESIS-G6682 
► Treatment of many medical disorders, such as diabetes hics. and other hormonal or metabolic imbalances, requires accurate blood analysis. Conventionally, blood is analyzed by withdrawing…
(more)
▼ Treatment of many medical disorders, such as diabetes hics. and other hormonal or metabolic imbalances, requires accurate blood analysis. Conventionally, blood is analyzed by withdrawing a sample from the body of the subject. One of the major disadvantages of conventional methods is the invasive nature of the tests that raise the risk of patient infection and discomfort. The polarimetric approach is currently being researched to determine glucose levels in the body non-invasively. Polarized light experiences a change in its plane of rotation that is proportional to the concentration of the sample when passed through an optically choral sample such as glucose. A multi-wavelength, multi-beam polarimetric device has been designed and implemented. The potential site for in-vivo measurements is the aqueous humor of the eye, which shows glucose concentrations proportional to the concentrations in the blood. The purpose of this dual wavelength device is to provide the means for overcoming two important problems with in-vivo glucose monitoring, namely, motion artifacts and the presence of other optically active substances at the test site. The device was tested in-vitro for accuracy and sensitivity. It predicted glucose to within an average standard deviation of 9.88mg/d1 for 670nm wavelength and 7.61mg/dl for the 820nm wavelength for the hyperglycemic ranges of 0-600mg/dl of glucose doped water. Improved results were obtained for glucose predictions in the hypoglycemic range of 0-100mg/dl of glucose. Glucose was predicted to within a standard deviation of 9.57mg/d1 for the 67013m wavelength and 5.35mg/dl for the 820nm wavelength. The system was also able to extract glucose information to within an average standard deviation of 24.41mg/dl from a solution of albumin and glucose, albumin being the other choral substance used in this study. Motion artifact studies indicated a clear trend of the two wavelengths in tracking each other, which potentially could be used to allow for glucose measurements in the presence of motion artifacts. The novelty of the system was its simultaneous dual wavelength approach and a fast feedback control system implemented in Labview. Overall, the results are satisfactory and show considerable being developed as an important approach to glucose potential in this technique sensing.
Subjects/Keywords: biomedical engineering.; Major biomedical engineering.
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APA (6th Edition):
Gorde, H. W. (2012). Multispectral polarimetric sensor for glucose monitoring utilizing a digital closed-loop control system. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/ETD-TAMU-1998-THESIS-G6682
Chicago Manual of Style (16th Edition):
Gorde, Harshal Wasudeo. “Multispectral polarimetric sensor for glucose monitoring utilizing a digital closed-loop control system.” 2012. Masters Thesis, Texas A&M University. Accessed April 15, 2021.
http://hdl.handle.net/1969.1/ETD-TAMU-1998-THESIS-G6682.
MLA Handbook (7th Edition):
Gorde, Harshal Wasudeo. “Multispectral polarimetric sensor for glucose monitoring utilizing a digital closed-loop control system.” 2012. Web. 15 Apr 2021.
Vancouver:
Gorde HW. Multispectral polarimetric sensor for glucose monitoring utilizing a digital closed-loop control system. [Internet] [Masters thesis]. Texas A&M University; 2012. [cited 2021 Apr 15].
Available from: http://hdl.handle.net/1969.1/ETD-TAMU-1998-THESIS-G6682.
Council of Science Editors:
Gorde HW. Multispectral polarimetric sensor for glucose monitoring utilizing a digital closed-loop control system. [Masters Thesis]. Texas A&M University; 2012. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-1998-THESIS-G6682
Texas A&M University
2.
Duraiswamy, Nandini.
Mechanical properties of normotensive and hypertensive carotid and coronary arteries and their quantification.
Degree: MS, biomedical engineering, 2012, Texas A&M University
URL: http://hdl.handle.net/1969.1/ETD-TAMU-2000-THESIS-D845
► Hypertension is a major risk factor for a variety of cardiovascular diseases like atherosclerosis, stroke, dissecting aortic aneurysms, etc. and is responsible for significant mortality…
(more)
▼ Hypertension is a major risk factor for a variety of cardiovascular diseases like atherosclerosis, stroke, dissecting aortic aneurysms, etc. and is responsible for significant mortality and morbidity. Hypertension results in changes in the arterial wall structure, properties, biology, and function because of the existence of mechanical stress, i.e., increased blood pressure. Experimental and theoretical results are published with different animal models of hypertension, and time course of occurrence of these changes is neglected. Hence, a lack of complete understanding exists. In this paper, in vitro multiaxial (cyclic stretch and inflation) tests were performed on live carotid and coronary arteries from an aortic coarctation hypertension model of pigs, subjected to two, five, and nine weeks of hypertension. We found that increased blood pressure induced changes in the multiaxial stress-stretch response of the tested arteries. Changes were significant both in the axial and circumferential directions. Passive and active residual stress measurements also showed changes in opening angles, radius to thickness ratio, thickness, and area. Experiments revealed considerable activation of the hypertensive specimens as compared to that of normotensive specimens. Finally, multiaxial data was fitted with the Fung's constitutive equation to predict the arterial behavior.
Subjects/Keywords: biomedical engineering.; Major biomedical engineering.
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APA (6th Edition):
Duraiswamy, N. (2012). Mechanical properties of normotensive and hypertensive carotid and coronary arteries and their quantification. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/ETD-TAMU-2000-THESIS-D845
Chicago Manual of Style (16th Edition):
Duraiswamy, Nandini. “Mechanical properties of normotensive and hypertensive carotid and coronary arteries and their quantification.” 2012. Masters Thesis, Texas A&M University. Accessed April 15, 2021.
http://hdl.handle.net/1969.1/ETD-TAMU-2000-THESIS-D845.
MLA Handbook (7th Edition):
Duraiswamy, Nandini. “Mechanical properties of normotensive and hypertensive carotid and coronary arteries and their quantification.” 2012. Web. 15 Apr 2021.
Vancouver:
Duraiswamy N. Mechanical properties of normotensive and hypertensive carotid and coronary arteries and their quantification. [Internet] [Masters thesis]. Texas A&M University; 2012. [cited 2021 Apr 15].
Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2000-THESIS-D845.
Council of Science Editors:
Duraiswamy N. Mechanical properties of normotensive and hypertensive carotid and coronary arteries and their quantification. [Masters Thesis]. Texas A&M University; 2012. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2000-THESIS-D845
Texas A&M University
3.
Prommin, Danu.
Mechanical bone strength in the proximal tibia.
Degree: MS, biomedical engineering, 2012, Texas A&M University
URL: http://hdl.handle.net/1969.1/ETD-TAMU-2000-THESIS-P74
► Six bone slices from one canine tibia were tested by compressive load to determine the ultimate strength as a function of distance from the knee.…
(more)
▼ Six bone slices from one canine tibia were tested by compressive load to determine the ultimate strength as a function of distance from the knee. Both the ultimate compressive strength and overall modulus of elasticity of tibial bone increased with increasing distance from the knee. However, over the first 15 mm the ultimate compressive strength is almost constant. Moreover, the changing cross-sectional area of cancellous bone conversely affects the changing strength and modulus of elasticity. These findings were a pilot study of the technique, which will subsequently be used for human tibial bone. Such data is relevant in the human with respect to the ability of the bone at various distances from the condyle to support the "flat-plate" loading of the tibial tray that is a standard component of total knee replacements.
Subjects/Keywords: biomedical engineering.; Major biomedical engineering.
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APA (6th Edition):
Prommin, D. (2012). Mechanical bone strength in the proximal tibia. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/ETD-TAMU-2000-THESIS-P74
Chicago Manual of Style (16th Edition):
Prommin, Danu. “Mechanical bone strength in the proximal tibia.” 2012. Masters Thesis, Texas A&M University. Accessed April 15, 2021.
http://hdl.handle.net/1969.1/ETD-TAMU-2000-THESIS-P74.
MLA Handbook (7th Edition):
Prommin, Danu. “Mechanical bone strength in the proximal tibia.” 2012. Web. 15 Apr 2021.
Vancouver:
Prommin D. Mechanical bone strength in the proximal tibia. [Internet] [Masters thesis]. Texas A&M University; 2012. [cited 2021 Apr 15].
Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2000-THESIS-P74.
Council of Science Editors:
Prommin D. Mechanical bone strength in the proximal tibia. [Masters Thesis]. Texas A&M University; 2012. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2000-THESIS-P74
Texas A&M University
4.
Satheesan, Bhavana.
Development of an automated optical system for corneal birefringence characterization.
Degree: MS, biomedical engineering, 2012, Texas A&M University
URL: http://hdl.handle.net/1969.1/ETD-TAMU-2000-THESIS-S275
► The aim of this project was the qualitative and quantitative characterization of the variations in the corneal birefringence in the rabbit eye through the design…
(more)
▼ The aim of this project was the qualitative and quantitative characterization of the variations in the corneal birefringence in the rabbit eye through the design and development of an automated optical setup. The results will be used for the development of a non-invasive optical polarimetric glucose sensor. In order to fully understand the various features that needed to be incorporated in the automated optical system, the initial stage of the research was spent in building and testing the manual optical system for Mueller matrix computation. The manual system was first characterized with a material of known birefringence, namely a 1/4 wave plate. The Mueller elements for different sets of rabbit eyes were then analyzed to determine the variation of intensities across the rabbit cornea for different Mueller elements. In addition the fast axis of the excised rabbit cornea was also determined. Using a manual system required 2-2 1/2 hours to collect the Mueller matrix images and increased risk of error, which was approximately 30%. Therefore, such a system for the end application of determining the Mueller matrix of the rabbit cornea in vivo was unsuitable. An automated system that overcame all the drawbacks of the manual system was required and hence designed and modeled. The operation of the automated system was verified by testing a sample whose Mueller matrix was known theoretically, namely the 1/4 wave retarder with its fast axis at different orientations. The results were in agreement with the theoretical values with an overall error percentage between the theoretical and the experimental of less than 15%. The time for collecting the Mueller matrix of a sample was a few minutes. Also, the data collected with the automated system was highly repeatable with a standard error percentage of less than 10%. Experiments with the automated optical system were conducted to determine the Mueller matrices of glucose at different concentrations and to determine the Mueller matrix of the cornea in an ex vivo rabbit eye.
Subjects/Keywords: biomedical engineering.; Major biomedical engineering.
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APA (6th Edition):
Satheesan, B. (2012). Development of an automated optical system for corneal birefringence characterization. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/ETD-TAMU-2000-THESIS-S275
Chicago Manual of Style (16th Edition):
Satheesan, Bhavana. “Development of an automated optical system for corneal birefringence characterization.” 2012. Masters Thesis, Texas A&M University. Accessed April 15, 2021.
http://hdl.handle.net/1969.1/ETD-TAMU-2000-THESIS-S275.
MLA Handbook (7th Edition):
Satheesan, Bhavana. “Development of an automated optical system for corneal birefringence characterization.” 2012. Web. 15 Apr 2021.
Vancouver:
Satheesan B. Development of an automated optical system for corneal birefringence characterization. [Internet] [Masters thesis]. Texas A&M University; 2012. [cited 2021 Apr 15].
Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2000-THESIS-S275.
Council of Science Editors:
Satheesan B. Development of an automated optical system for corneal birefringence characterization. [Masters Thesis]. Texas A&M University; 2012. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2000-THESIS-S275
Texas A&M University
5.
Tay, Edward Chor-Ying.
Modeling the transmission of HIV in the Texas State Prison population.
Degree: MS, biomedical engineering, 2012, Texas A&M University
URL: http://hdl.handle.net/1969.1/ETD-TAMU-2000-THESIS-T38
► An infectious disease that is widespread globally is acquired immune deficiency syndrome (AIDS). AIDS is spread by the human immunodeficiency virus (HIV). The purpose of…
(more)
▼ An infectious disease that is widespread globally is acquired immune deficiency syndrome (AIDS). AIDS is spread by the human immunodeficiency virus (HIV). The purpose of this study was to develop a simulation model to study the transmission of HIV via intravenous drug use in a Texas State prison population. By developing a model to track the movement of HIV in the prison, public health authorities could suggest policies to better serve those HIV positive prisoners released into the general population. Also, this model provided a means to quantitatively study the effect of intervention strategies against the virus (increase or reduction of infection rate). The minimum-security prison of Huntsville, Texas, was chosen as the site for the simulation study. Parameter values were estimated from data in existing literature. Vital statistics such as the mean number of prisoners without HIV, with HIV, and those with AIDS were collected and analyzed at the end of 10 years. Simulation schemes were structured on an event driven basis, the existence of syringes in prison by smuggling, or no syringes in prison. A parametric analysis was conducted by changing three of the parameters one at a time: the probability of syringe smuggling, the probability of a newly admitted prisoner to be HIV positive, and the mean number of injections per day Results from the base run showed that there were more than 3 infections per syringe-existing day, or about 0.2% of the prison population. Successful syringe smuggling translated into HIV transmission of anywhere from 3 to more than 20 new infectives per virus spreading event period. These numbers are alarming, as this would reach epidemic proportions. Results from the parametric analysis showed that most of the HIV positives released were a result of syringe sharing and most of the prisoners who developed AIDS were from prisoners admitted into prison with HIV. The structure and procedure of this simulation model can be employed to study other epidemics that may threaten public health. By using our simulation model as a basis, models could be developed to study other infectious diseases and in different types of environments.
Subjects/Keywords: biomedical engineering; Major biomedical engineering
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APA (6th Edition):
Tay, E. C. (2012). Modeling the transmission of HIV in the Texas State Prison population. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/ETD-TAMU-2000-THESIS-T38
Chicago Manual of Style (16th Edition):
Tay, Edward Chor-Ying. “Modeling the transmission of HIV in the Texas State Prison population.” 2012. Masters Thesis, Texas A&M University. Accessed April 15, 2021.
http://hdl.handle.net/1969.1/ETD-TAMU-2000-THESIS-T38.
MLA Handbook (7th Edition):
Tay, Edward Chor-Ying. “Modeling the transmission of HIV in the Texas State Prison population.” 2012. Web. 15 Apr 2021.
Vancouver:
Tay EC. Modeling the transmission of HIV in the Texas State Prison population. [Internet] [Masters thesis]. Texas A&M University; 2012. [cited 2021 Apr 15].
Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2000-THESIS-T38.
Council of Science Editors:
Tay EC. Modeling the transmission of HIV in the Texas State Prison population. [Masters Thesis]. Texas A&M University; 2012. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2000-THESIS-T38
Texas A&M University
6.
Banatwala, Marissa Zainuddin.
Computational analysis and the geometry of intracranial saccular aneurysms.
Degree: MS, biomedical engineering, 2012, Texas A&M University
URL: http://hdl.handle.net/1969.1/ETD-TAMU-2001-THESIS-B334
► Intracranial saccular aneurysms present a very challenging problem both clinically and for the bioengineer. As long as a complete understanding of their material properties is…
(more)
▼ Intracranial saccular aneurysms present a very challenging problem both clinically and for the bioengineer. As long as a complete understanding of their material properties is unavailable, other ways to gain insight into their potential for rupture must be sought. Because aneurysms do not present in nature as simple, easily describable entities, a thorough analysis of their geometry is a necessary first step. This thesis attempts to further the body of knowledge available on this vital issue by applying surface patch methods for the computation of local curvatures, previously used in the analysis of abdominal aortic aneurysms, to the study of intracranial saccular aneurysms. This thesis also examines preliminary stress resultant calculations based on these calculated curvatures. Finally, a class of equations, Legendre functions of the first kind, are introduced and shown to provide a more accurate description of aneurysm geometry than the commonly used spherical geometry.
Subjects/Keywords: biomedical engineering.; Major biomedical engineering.
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APA (6th Edition):
Banatwala, M. Z. (2012). Computational analysis and the geometry of intracranial saccular aneurysms. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/ETD-TAMU-2001-THESIS-B334
Chicago Manual of Style (16th Edition):
Banatwala, Marissa Zainuddin. “Computational analysis and the geometry of intracranial saccular aneurysms.” 2012. Masters Thesis, Texas A&M University. Accessed April 15, 2021.
http://hdl.handle.net/1969.1/ETD-TAMU-2001-THESIS-B334.
MLA Handbook (7th Edition):
Banatwala, Marissa Zainuddin. “Computational analysis and the geometry of intracranial saccular aneurysms.” 2012. Web. 15 Apr 2021.
Vancouver:
Banatwala MZ. Computational analysis and the geometry of intracranial saccular aneurysms. [Internet] [Masters thesis]. Texas A&M University; 2012. [cited 2021 Apr 15].
Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2001-THESIS-B334.
Council of Science Editors:
Banatwala MZ. Computational analysis and the geometry of intracranial saccular aneurysms. [Masters Thesis]. Texas A&M University; 2012. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2001-THESIS-B334
Texas A&M University
7.
Borade, Pravin.
Physician Preference Cardiac Alert Modality system.
Degree: MS, biomedical engineering, 2012, Texas A&M University
URL: http://hdl.handle.net/1969.1/ETD-TAMU-2001-THESIS-B65
► Since the parameters used for diagnosis may differ from physician to physician, the attending medical staff often finds it confusing to make a decision as…
(more)
▼ Since the parameters used for diagnosis may differ from physician to physician, the attending medical staff often finds it confusing to make a decision as to whether or not to notify the particular physician of their patient's present condition and wait for the physician or to act on their own. This thesis is an attempt at developing a system that inculcates the diagnosis routine into the critical patient monitoring system with alarm capabilities, thus assisting the attending medical staff with a pre-determined set of patient emergencies and helping them in the timely diagnosis of the probable cause. Since the system also has the added advantage of the diagnosis module, it is helpful to the attending medical staff in acting immediately upon possible patient condition deterioration as it begins. The Physician Preference Cardiac Alert Modality (PPCAM) system is not intended to replace physicians, but to aid them. When used in the physicians' office, this system may assist them in their independent patient diagnosis and evaluation. This system design makes use of the obtained patient data, medication history, physical examination results, and trend panel readings, which provide understanding of the patient's state. The most important aspects of the PPCAM system, the parameter estimation process and the diagnosis module programming are discussed. This is an attempt at developing a simple system for data integration, clinical information presentation and possible diagnoses in an attempt to build a rule-based automated cardiac monitoring system at a reduced cost as compared to current commercial systems that perform some of these functions.
Subjects/Keywords: biomedical engineering.; Major biomedical engineering.
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APA (6th Edition):
Borade, P. (2012). Physician Preference Cardiac Alert Modality system. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/ETD-TAMU-2001-THESIS-B65
Chicago Manual of Style (16th Edition):
Borade, Pravin. “Physician Preference Cardiac Alert Modality system.” 2012. Masters Thesis, Texas A&M University. Accessed April 15, 2021.
http://hdl.handle.net/1969.1/ETD-TAMU-2001-THESIS-B65.
MLA Handbook (7th Edition):
Borade, Pravin. “Physician Preference Cardiac Alert Modality system.” 2012. Web. 15 Apr 2021.
Vancouver:
Borade P. Physician Preference Cardiac Alert Modality system. [Internet] [Masters thesis]. Texas A&M University; 2012. [cited 2021 Apr 15].
Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2001-THESIS-B65.
Council of Science Editors:
Borade P. Physician Preference Cardiac Alert Modality system. [Masters Thesis]. Texas A&M University; 2012. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2001-THESIS-B65
Texas A&M University
8.
Dawes, Derek Shawn.
Analysis of SaO₂ & heart rate from the combined PBG/PBA study.
Degree: MS, biomedical engineering, 2012, Texas A&M University
URL: http://hdl.handle.net/1969.1/ETD-TAMU-2001-THESIS-D387
► Pilots routinely utilize positive pressure breathing to prevent hypoxia while flying at high altitudes. In addition, positive pressure breathing is also exploited to avoid syncope…
(more)
▼ Pilots routinely utilize positive pressure breathing to prevent hypoxia while flying at high altitudes. In addition, positive pressure breathing is also exploited to avoid syncope while pilots experience elevated Gz levels. This study evaluates the effects on heart rate and oxygen saturation of transitioning from positive pressure breathing for increased Gz load to positive pressure breathing for altitude. Analysis was performed on previously recorded data taken with permission from Brooks United States Air Force Base in San Antonio, Texas. The findings indicate that while SaO₂ level changes are not statistically significant, heart rate changes are considerable when transitioning to increased Gz level.
Subjects/Keywords: biomedical engineering.; Major biomedical engineering.
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APA (6th Edition):
Dawes, D. S. (2012). Analysis of SaO₂ & heart rate from the combined PBG/PBA study. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/ETD-TAMU-2001-THESIS-D387
Chicago Manual of Style (16th Edition):
Dawes, Derek Shawn. “Analysis of SaO₂ & heart rate from the combined PBG/PBA study.” 2012. Masters Thesis, Texas A&M University. Accessed April 15, 2021.
http://hdl.handle.net/1969.1/ETD-TAMU-2001-THESIS-D387.
MLA Handbook (7th Edition):
Dawes, Derek Shawn. “Analysis of SaO₂ & heart rate from the combined PBG/PBA study.” 2012. Web. 15 Apr 2021.
Vancouver:
Dawes DS. Analysis of SaO₂ & heart rate from the combined PBG/PBA study. [Internet] [Masters thesis]. Texas A&M University; 2012. [cited 2021 Apr 15].
Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2001-THESIS-D387.
Council of Science Editors:
Dawes DS. Analysis of SaO₂ & heart rate from the combined PBG/PBA study. [Masters Thesis]. Texas A&M University; 2012. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2001-THESIS-D387
Texas A&M University
9.
Feng, Dazi.
Microwave-induced thermoacoustic tomography: reconstruction by synthetic aperture.
Degree: MS, biomedical engineering, 2012, Texas A&M University
URL: http://hdl.handle.net/1969.1/ETD-TAMU-2001-THESIS-F39
► We have applied the synthetic-aperture method to linear-scanning microwave-induced thermoacoustic tomography in biological tissues. A non-focused ultrasonic transducer was used to receive thermoacoustic signals, to…
(more)
▼ We have applied the synthetic-aperture method to linear-scanning microwave-induced thermoacoustic tomography in biological tissues. A non-focused ultrasonic transducer was used to receive thermoacoustic signals, to which the delay-and-sum algorithm was applied for image reconstruction. We greatly improved the lateral resolution of images and acquired a clear view of the circular boundaries of buried cylindrical objects, which could not be obtained in conventional linear-scanning microwave-induced thermoacoustic tomography (LMTT) based on focused transducers. Two microwave sources, which had frequencies of 9 GHz and 3 GHz, respectively, were used in the experiments for comparison. The 3-GHz system had a much larger imaging depth but a lower signal-noise ratio than the 9-GHz system.
Subjects/Keywords: biomedical engineering.; Major biomedical engineering.
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APA (6th Edition):
Feng, D. (2012). Microwave-induced thermoacoustic tomography: reconstruction by synthetic aperture. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/ETD-TAMU-2001-THESIS-F39
Chicago Manual of Style (16th Edition):
Feng, Dazi. “Microwave-induced thermoacoustic tomography: reconstruction by synthetic aperture.” 2012. Masters Thesis, Texas A&M University. Accessed April 15, 2021.
http://hdl.handle.net/1969.1/ETD-TAMU-2001-THESIS-F39.
MLA Handbook (7th Edition):
Feng, Dazi. “Microwave-induced thermoacoustic tomography: reconstruction by synthetic aperture.” 2012. Web. 15 Apr 2021.
Vancouver:
Feng D. Microwave-induced thermoacoustic tomography: reconstruction by synthetic aperture. [Internet] [Masters thesis]. Texas A&M University; 2012. [cited 2021 Apr 15].
Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2001-THESIS-F39.
Council of Science Editors:
Feng D. Microwave-induced thermoacoustic tomography: reconstruction by synthetic aperture. [Masters Thesis]. Texas A&M University; 2012. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2001-THESIS-F39
Texas A&M University
10.
Delange, Sherry Leanne.
Biomechanics of the lens capsule.
Degree: MS, biomedical engineering, 2012, Texas A&M University
URL: http://hdl.handle.net/1969.1/ETD-TAMU-2002-THESIS-D422
► Data on the mechanical properties of the lens capsule available in the literature are limited, providing only global and 1-D information. There has yet to…
(more)
▼ Data on the mechanical properties of the lens capsule available in the literature are limited, providing only global and 1-D information. There has yet to be any systematic, rigorous study of the nonlinear multiaxial biomechanics of the lens capsule. First and foremost, there is a need to delineate the general characteristics of the lens capsule and to identify any regional differences that may exist. Thus, the goal of this work was to design and construct an experimental system to load the lens capsule multiaxially in its intact, native configuration and to quantify the general characteristics via pressure-strain data. This experimental system alters the stresses in the normal porcine anterior lens capsule, thereby allowing local displacement gradients and, in turn, deformation gradients to be calculated. Such data are needed to compute the multiaxial strain fields. In this study, cyclic inflation tests were performed over pressures ranging from P = {0, 45 mmHg}, and creep tests were performed at a constant inflation pressure P = 45 mmHg.
Subjects/Keywords: biomedical engineering.; Major biomedical engineering.
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APA (6th Edition):
Delange, S. L. (2012). Biomechanics of the lens capsule. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/ETD-TAMU-2002-THESIS-D422
Chicago Manual of Style (16th Edition):
Delange, Sherry Leanne. “Biomechanics of the lens capsule.” 2012. Masters Thesis, Texas A&M University. Accessed April 15, 2021.
http://hdl.handle.net/1969.1/ETD-TAMU-2002-THESIS-D422.
MLA Handbook (7th Edition):
Delange, Sherry Leanne. “Biomechanics of the lens capsule.” 2012. Web. 15 Apr 2021.
Vancouver:
Delange SL. Biomechanics of the lens capsule. [Internet] [Masters thesis]. Texas A&M University; 2012. [cited 2021 Apr 15].
Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2002-THESIS-D422.
Council of Science Editors:
Delange SL. Biomechanics of the lens capsule. [Masters Thesis]. Texas A&M University; 2012. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2002-THESIS-D422
Texas A&M University
11.
DeLaughter, Aimee Hill.
The use of polarized light for skin cancer detecton.
Degree: MS, biomedical engineering, 2012, Texas A&M University
URL: http://hdl.handle.net/1969.1/ETD-TAMU-2002-THESIS-D423
► Over 50,000 people per year will be diagnosed with skin cancer in one of its various forms, making it the seventh most common form of…
(more)
▼ Over 50,000 people per year will be diagnosed with skin cancer in one of its various forms, making it the seventh most common form of cancer in the United States. Currently the only method to diagnose suspicious lesions is visual inspection and subsequent biopsy of suspicious lesions. Many cancerous lesions are missed and many benign lesions are biopsied using these techniques. This process is painful and expensive. The proposed research is driven by the need for a non-invasive skin cancer detection system. Presented here is a method for the optical determination of cancerous tissue using polarized light. This thesis describes the development of a polarimetric imaging system including its calibration and testing. In addition, experiments are performed to simulate changes in tissue, such as increased size of scatterers and increased scattering and absorption coefficients that often accompany tissue changes as it becomes cancerous. The effects of these simulated changes are tested on the Polarimetric imaging system in order to quantify changes in the Mueller matrix caused by the perturbations, and ultimately to relate them to observed changes in the Mueller matrices of cancerous and non-cancerous tissue. Finally, the Polarimetric imaging system is used to determine the Mueller matrix of cancerous and non-cancerous tissue to assess the system's capabilities for skin cancer diagnosis.
Subjects/Keywords: biomedical engineering.; Major biomedical engineering.
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APA (6th Edition):
DeLaughter, A. H. (2012). The use of polarized light for skin cancer detecton. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/ETD-TAMU-2002-THESIS-D423
Chicago Manual of Style (16th Edition):
DeLaughter, Aimee Hill. “The use of polarized light for skin cancer detecton.” 2012. Masters Thesis, Texas A&M University. Accessed April 15, 2021.
http://hdl.handle.net/1969.1/ETD-TAMU-2002-THESIS-D423.
MLA Handbook (7th Edition):
DeLaughter, Aimee Hill. “The use of polarized light for skin cancer detecton.” 2012. Web. 15 Apr 2021.
Vancouver:
DeLaughter AH. The use of polarized light for skin cancer detecton. [Internet] [Masters thesis]. Texas A&M University; 2012. [cited 2021 Apr 15].
Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2002-THESIS-D423.
Council of Science Editors:
DeLaughter AH. The use of polarized light for skin cancer detecton. [Masters Thesis]. Texas A&M University; 2012. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2002-THESIS-D423
Texas A&M University
12.
Everett, William Neil.
Bi-plane video-based determination of strains in arterial bifurcations.
Degree: MS, biomedical engineering, 2012, Texas A&M University
URL: http://hdl.handle.net/1969.1/ETD-TAMU-2002-THESIS-E96
► Subarachnoid hemorrhage following the rupture of a cerebral aneurysm is one of the most devastating neurological catastrophes affecting adults. It has been well documented that…
(more)
▼ Subarachnoid hemorrhage following the rupture of a cerebral aneurysm is one of the most devastating neurological catastrophes affecting adults. It has been well documented that cerebral aneurysms frequently form at arterial branching sites; more specifically, on either side of the apex of a bifurcation. For decades it has been assumed that an inherent medial deficiency, termed "medial defect," at the apex was one source for initial development. Based upon recent histological studies of the apical region in cerebral arteries, Finlay et al (1998) hypothesized that a stress concentration may exist in the region adjacent to the apex. Along the apex they found a narrow and highly-oriented collagen band, which refutes previous claims of apical weakness; on the other hand, the existence of such a structure may lead to a sharp material discontinuity in the region, promoting the formation of cerebral aneurysms. To test the validity of their claim, a device was constructed capable of orienting a bifurcation in its native configuration, applying static loads, and optically measuring marker displacements. Bovine left coronary arteries were excised, and excess adventitia was removed from the apical region. Seventy-five to one hundred black microspheres, approximately 50æm in diameter, were glued to the surface of the branching region. The marker group was spatially reconstructed using bi-plane video imaging. Subsequently, a mesh of marker triplets was created and a 2-D homogeneous approximation of Green's strain (E) was found for each domain at four pressures: 40, 60, 80, and 120mmHg (the reference pressure was 20mmHg). A color assignment, based upon the relative intensity of the first invariant of E (I[E]), was given to each domain within the mesh and plotted accordingly. Our results revealed no apparent trends with regard to high strain gradients near the apical region. Difficulties with system resolution introduced pixel selection error, leading to a high degree of uncertainty for strain calculations. For example, errors as large as one third the value of I[E] for smaller domains could be substantiated. Yet, strains were typically within one standard error in most domains and we concluded that the approximated strain field in the coronary bifurcation was nearly homogeneous to within experimental error.
Subjects/Keywords: biomedical engineering.; Major biomedical engineering.
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APA (6th Edition):
Everett, W. N. (2012). Bi-plane video-based determination of strains in arterial bifurcations. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/ETD-TAMU-2002-THESIS-E96
Chicago Manual of Style (16th Edition):
Everett, William Neil. “Bi-plane video-based determination of strains in arterial bifurcations.” 2012. Masters Thesis, Texas A&M University. Accessed April 15, 2021.
http://hdl.handle.net/1969.1/ETD-TAMU-2002-THESIS-E96.
MLA Handbook (7th Edition):
Everett, William Neil. “Bi-plane video-based determination of strains in arterial bifurcations.” 2012. Web. 15 Apr 2021.
Vancouver:
Everett WN. Bi-plane video-based determination of strains in arterial bifurcations. [Internet] [Masters thesis]. Texas A&M University; 2012. [cited 2021 Apr 15].
Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2002-THESIS-E96.
Council of Science Editors:
Everett WN. Bi-plane video-based determination of strains in arterial bifurcations. [Masters Thesis]. Texas A&M University; 2012. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2002-THESIS-E96
Texas A&M University
13.
Sainath, Paavana.
Virtual doctor's office telemedicine delivery system.
Degree: MS, biomedical engineering, 2012, Texas A&M University
URL: http://hdl.handle.net/1969.1/ETD-TAMU-2002-THESIS-S243
► Rapid advances in high performance global communication have accelerated telemedicine-based medical services to a new frontier. Traditional medical services can now fully utilize multimedia technologies…
(more)
▼ Rapid advances in high performance global communication have accelerated telemedicine-based medical services to a new frontier. Traditional medical services can now fully utilize multimedia technologies to provide novel services, such as tele-consultation and remote cooperative medical triage, virtual simulation of health care delivery and fast and easy retrieval of relevant information, which is perhaps the most critical requirement for the provision of remote medical services. This project aims to research and develop components and systems of health service delivery using advanced telecommunications between remote communities, applicable to one of two scenarios - with the presence of a healthcare provider and without (homecare). The components of health service delivery involve consultations between physicians located at a distant location, which could be within tertiary medical care facilities, and attending physicians located in remote communities. The project involves research and development of telemedicine delivery services that are two-way telecommunications using a File Transfer Protocol over an Ethernet connection. The system is used to demonstrate effective telemedicine delivery to enable tele-consultation. Virtual instruments are developed for both ends of the system to acquire the relevant medical information, suitably format the data for transmission, and reproduce the recovered information, as necessary.
Subjects/Keywords: biomedical engineering.; Major biomedical engineering.
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APA (6th Edition):
Sainath, P. (2012). Virtual doctor's office telemedicine delivery system. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/ETD-TAMU-2002-THESIS-S243
Chicago Manual of Style (16th Edition):
Sainath, Paavana. “Virtual doctor's office telemedicine delivery system.” 2012. Masters Thesis, Texas A&M University. Accessed April 15, 2021.
http://hdl.handle.net/1969.1/ETD-TAMU-2002-THESIS-S243.
MLA Handbook (7th Edition):
Sainath, Paavana. “Virtual doctor's office telemedicine delivery system.” 2012. Web. 15 Apr 2021.
Vancouver:
Sainath P. Virtual doctor's office telemedicine delivery system. [Internet] [Masters thesis]. Texas A&M University; 2012. [cited 2021 Apr 15].
Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2002-THESIS-S243.
Council of Science Editors:
Sainath P. Virtual doctor's office telemedicine delivery system. [Masters Thesis]. Texas A&M University; 2012. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2002-THESIS-S243
Texas A&M University
14.
Smith, Katherine Elizabeth.
Mechanical properties of normotensive and hypertensive female rat carotid arteries.
Degree: MS, biomedical engineering, 2012, Texas A&M University
URL: http://hdl.handle.net/1969.1/ETD-TAMU-2002-THESIS-S626
► In response to chronic hypertension, the heart and vasculature exhibit morphologic changes that reflect alterations in net gains and losses of their cellular components, i.e.…
(more)
▼ In response to chronic hypertension, the heart and vasculature exhibit morphologic changes that reflect alterations in net gains and losses of their cellular components, i.e. they grow and remodel. Vascular remodeling is manifested mechanically as an altered response to applied loads. This remodeling may differ by sex and direction within the vascular wall. In an effort to better understand remodeling, this study examined female Sprague-Dawley rats 10-12 days post aortic coarctation or sham surgery. The objectives of this study were threefold: (1) to design and build a system to allow quantification of thromboxane A₂ produced from cylindrical segments of hypertensive and normotensive rat aortas, (2) to quantify the response of hypertensive and normotensive female rat carotid arteries to applied loads considering active and passive responses in the longitudinal and circumferential directions, and (3) to compare the female response in both groups to data available for males. The first objective provides the means to examine sex differences in thromboxane A₂ production, which may be important in remodeling. The second objective involved pressure-diameter tests (with specimen preconditioning) and opening angle tests in both active and passive states. There were no statistically significant differences between normotensive and hypertensive opening angle results or the slopes of passive mean circumferential stress and mean axial stress vs. circumferential stretch plots. Mean passive axial stress was greater in hypertensives than controls for a given axial stretch. Altered passive axial properties indicate a difference from controls in collagen, elastin, or the passive properties of smooth muscle cells. No generalizations were made from the active tests since only the first loading cycle showed evidence of contraction, and most data collected were post preconditioning. Comparable studies on male rats demonstrate statistically significant differences in both histological and mechanical properties by 8 days post-coarctation (Fridez et al, 2001). The lack of similar findings here may relate to gender differences in the time-course or extent of remodeling. Future studies should devote careful attention to sex differences in multi-axial properties and active vs. passive remodeling. The role of preconditioning in active mechanical tests and the time course of remodeling should be addressed.
Subjects/Keywords: biomedical engineering.; Major biomedical engineering.
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APA (6th Edition):
Smith, K. E. (2012). Mechanical properties of normotensive and hypertensive female rat carotid arteries. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/ETD-TAMU-2002-THESIS-S626
Chicago Manual of Style (16th Edition):
Smith, Katherine Elizabeth. “Mechanical properties of normotensive and hypertensive female rat carotid arteries.” 2012. Masters Thesis, Texas A&M University. Accessed April 15, 2021.
http://hdl.handle.net/1969.1/ETD-TAMU-2002-THESIS-S626.
MLA Handbook (7th Edition):
Smith, Katherine Elizabeth. “Mechanical properties of normotensive and hypertensive female rat carotid arteries.” 2012. Web. 15 Apr 2021.
Vancouver:
Smith KE. Mechanical properties of normotensive and hypertensive female rat carotid arteries. [Internet] [Masters thesis]. Texas A&M University; 2012. [cited 2021 Apr 15].
Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2002-THESIS-S626.
Council of Science Editors:
Smith KE. Mechanical properties of normotensive and hypertensive female rat carotid arteries. [Masters Thesis]. Texas A&M University; 2012. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2002-THESIS-S626
Texas A&M University
15.
Srinivasan, Niranjana.
Model for a web-based hospital technology management system.
Degree: MS, biomedical engineering, 2012, Texas A&M University
URL: http://hdl.handle.net/1969.1/ETD-TAMU-2002-THESIS-S68
► The objective of this project is to design a hospital technology management system that is web-based. Technology management may be defined as 'an accountable, systematic…
(more)
▼ The objective of this project is to design a hospital technology management system that is web-based. Technology management may be defined as 'an accountable, systematic approach to ensure that cost-effective, efficacious, safe and appropriate equipment is available to meet the demands of quality patient care'. Often, technology management in large hospitals can be a very challenging proposition due to the large numbers and categories of the equipment in such sizes of facilities. For instance, a hospital with a medium sized bed capacity of 500 beds could have greater than 4000 pieces of equipment. These range from simple thermometers and stethoscopes to complex CAT scanners and imaging equipment such as MRI. Technology management in such facilities would encompass inventory control, vendor selection, risk management, maintenance scheduling and staff training scheduling. Common offshoots of not having effective technology management for such a facility include the inadvertent use of faulty or poorly designed equipment or the inappropriate use of otherwise proper equipment by untrained staff. It is the job of clinical engineers in medical establishments to carry out technology management. They rely on information from the FDA and medical device manufacturers to do this. Sometimes, the FDA may deem a particular device unsuitable for safe use and clinical engineers have to rely on seeing this information in a timely way to make the decisions regarding usage and management of that equipment, when it is present in their inventory. Currently there are computerized maintenance and management systems which offer various features. The focus of this thesis was to improve the usefulness by implementing a system which would automatically obtain FDA and device manufacturers' information about equipment so that the clinical engineer can obtain this information in a timely manner. The system would be accessible to the hospital staff over the Internet. It would provide data about other aspects of device management such as, whether users have been trained in its use, history of failures and user errors on the device, history of usage and downtime. Such a system could help clinical engineers ensure that the properly trained people, to secure patient safety, use the most suitable equipment.
Subjects/Keywords: biomedical engineering.; Major biomedical engineering.
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APA (6th Edition):
Srinivasan, N. (2012). Model for a web-based hospital technology management system. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/ETD-TAMU-2002-THESIS-S68
Chicago Manual of Style (16th Edition):
Srinivasan, Niranjana. “Model for a web-based hospital technology management system.” 2012. Masters Thesis, Texas A&M University. Accessed April 15, 2021.
http://hdl.handle.net/1969.1/ETD-TAMU-2002-THESIS-S68.
MLA Handbook (7th Edition):
Srinivasan, Niranjana. “Model for a web-based hospital technology management system.” 2012. Web. 15 Apr 2021.
Vancouver:
Srinivasan N. Model for a web-based hospital technology management system. [Internet] [Masters thesis]. Texas A&M University; 2012. [cited 2021 Apr 15].
Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2002-THESIS-S68.
Council of Science Editors:
Srinivasan N. Model for a web-based hospital technology management system. [Masters Thesis]. Texas A&M University; 2012. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2002-THESIS-S68
Texas A&M University
16.
Theru, Sangeeta.
Modeling of the corneal layer of the rabbit's eye using Mueller matrix analysis.
Degree: MS, biomedical engineering, 2012, Texas A&M University
URL: http://hdl.handle.net/1969.1/ETD-TAMU-2002-THESIS-T443
► The aim of this project was to theoretically model the propagation of polarized light through the corneal layer of the anterior chamber of the rabbit's…
(more)
▼ The aim of this project was to theoretically model the propagation of polarized light through the corneal layer of the anterior chamber of the rabbit's eye as a Mueller matrix and to verify the model experimentally. The results will be utilized for the research conducted towards the development of a noninvasive in vivo blood glucose sensor using optical polarimetric methods. The sensitivity and performance of the noninvasive glucose sensor is greatly affected by the birefringence of the corneal layer of the eye, which varies due to the random motion of the eye induced by the respiratory and cardiac processes. Corneal birefringence changes the polarization-state of the input light as it passes through the anterior chamber of the eye. Several parameters that could possibly influence the state of polarization include the birefringence of the cornea at the point of incidence of input light, the thickness of the cornea, the orientation of the fast axis of the cornea at the point of incidence, and the wavelength of light used. The cornea was effectively modeled as a linear retarder to take into account these parameters. The optical system designed and built for the verification of the theoretical model was characterized and calibrated using a known sample, namely a birefringent quarter wave retarder with the fast axis at different orientations (to simulate the corneal layer of the eye). Once this was achieved, the system was used to obtain data on ex vivo rabbit eyes. The data was collected for different positions on each eye. The experimental results were then compared with the theoretical results and the intensity variations due to changes in the polarization-state of the input incident light were analyzed. The change in the intensity for the elements of the Mueller matrix characterizes the optical nature of the corneal layer of the rabbit eye. The experimental results were in good agreement with the theoretical results.
Subjects/Keywords: biomedical engineering.; Major biomedical engineering.
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APA (6th Edition):
Theru, S. (2012). Modeling of the corneal layer of the rabbit's eye using Mueller matrix analysis. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/ETD-TAMU-2002-THESIS-T443
Chicago Manual of Style (16th Edition):
Theru, Sangeeta. “Modeling of the corneal layer of the rabbit's eye using Mueller matrix analysis.” 2012. Masters Thesis, Texas A&M University. Accessed April 15, 2021.
http://hdl.handle.net/1969.1/ETD-TAMU-2002-THESIS-T443.
MLA Handbook (7th Edition):
Theru, Sangeeta. “Modeling of the corneal layer of the rabbit's eye using Mueller matrix analysis.” 2012. Web. 15 Apr 2021.
Vancouver:
Theru S. Modeling of the corneal layer of the rabbit's eye using Mueller matrix analysis. [Internet] [Masters thesis]. Texas A&M University; 2012. [cited 2021 Apr 15].
Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2002-THESIS-T443.
Council of Science Editors:
Theru S. Modeling of the corneal layer of the rabbit's eye using Mueller matrix analysis. [Masters Thesis]. Texas A&M University; 2012. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2002-THESIS-T443
Texas A&M University
17.
Bartsch, Heather Renee.
Histomechanics of arteries due to altered mechanical forces.
Degree: MS, biomedical engineering, 2012, Texas A&M University
URL: http://hdl.handle.net/1969.1/ETD-TAMU-2003-THESIS-B372
► Mechanical forces such as shear stress and pressure affect the cells of the arterial wall. Large arteries seek to maintain an optimal shear stress of…
(more)
▼ Mechanical forces such as shear stress and pressure affect the cells of the arterial wall. Large arteries seek to maintain an optimal shear stress of 1.5 Pa and a circumferential stress of 100 kPa; when conditions such as pressure and flow are altered, the vessel undergoes both acute and long-term changes in an attempt to restore normalcy. In response to reduced flow, the vessel constricts acutely and the wall thickens; increased flow causes dilation and the wall's thickness decreases. In contrast, increased pressure, or the pathological condition known as hypertension, induces wall thickening while maintaining a relatively constant lumen diameter. Since mechanical forces affect the blood vessel at the cellular level, histology becomes a convenient and useful tool in visualizing gross morphological changes and molecular changes in the cell. Quantitative histology endeavors to analyze and quantify parameters of interest from histological images. Current quantitative histological methods, however, are not objective and often rely on the user selection the region of interest to be measured. Consequently, a semi-automatic image analysis system was created using MetaMorph (MM), an image analysis software package, and Visual Basic (VB)5.0. By writing code in VB, MM's capabilities were extended to perform novel measurements including circumferential measurements of wall thickness and radial and circumferential gradients of elastin and collagen in the vessel wall. Other parameters of interest that were measured included lumen diameter and average wall thickness.
Subjects/Keywords: biomedical engineering.; Major biomedical engineering.
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APA (6th Edition):
Bartsch, H. R. (2012). Histomechanics of arteries due to altered mechanical forces. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/ETD-TAMU-2003-THESIS-B372
Chicago Manual of Style (16th Edition):
Bartsch, Heather Renee. “Histomechanics of arteries due to altered mechanical forces.” 2012. Masters Thesis, Texas A&M University. Accessed April 15, 2021.
http://hdl.handle.net/1969.1/ETD-TAMU-2003-THESIS-B372.
MLA Handbook (7th Edition):
Bartsch, Heather Renee. “Histomechanics of arteries due to altered mechanical forces.” 2012. Web. 15 Apr 2021.
Vancouver:
Bartsch HR. Histomechanics of arteries due to altered mechanical forces. [Internet] [Masters thesis]. Texas A&M University; 2012. [cited 2021 Apr 15].
Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2003-THESIS-B372.
Council of Science Editors:
Bartsch HR. Histomechanics of arteries due to altered mechanical forces. [Masters Thesis]. Texas A&M University; 2012. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2003-THESIS-B372
Texas A&M University
18.
Lee, Seung Joon.
Near-infrared approaches for cell culture monitoring.
Degree: MS, biomedical engineering, 2012, Texas A&M University
URL: http://hdl.handle.net/1969.1/ETD-TAMU-2003-THESIS-L443
► Current techniques for monitoring glucose and lactate concentrations in cell culture media require invasive and tedious handling of the sample for sterile media removal and…
(more)
▼ Current techniques for monitoring glucose and lactate concentrations in cell culture media require invasive and tedious handling of the sample for sterile media removal and nutrient replacement. Even though in situ or ex situ analyte monitoring systems have been tried for on-line measurement, they suffer from difficulties including the inability to keep them sterile, their limited lifetime, and their lack of stability. In order to optimize cell culture growth in bioreactors, biosensors must be developed that are capable of monitoring cell culture parameters such as analyte concentration and cell concentration non-invasively and continuously. For this research, noninvasive determinations of glucose and lactate in cell culture media were investigated using near-infrared spectroscopy across the 2.0-2.5 mm spectral region. A system was developed using a Fourier Transform Infrared (FT-IR) spectrometer and optical fibers to characterize glucose and lactate absorbance spectra in cell culture media from hybridoma cell culture. Partial least squares (PLS) regression has been used to extract the analyte-dependent information and to build a successful multivariate calibration model. Calibration, using a combination of spectra from cell culture media and spiked sample media mixtures, was performed and applied to an independent validation data set, producing a prediction error of 1.7 % and 9.8 % for glucose and lactate, respectively. In addition, a noninvasive optical cell density monitoring system based on a laser turbidity sensor was developed. The total cell concentration predicted with optical method was in excellent agreement with off-line cell counting data. The results from the two experiments suggest that such analyte concentration and laser turbidity systems could potentially be used for on-line monitoring and control of animal cell cultivations in a bioreactor.
Subjects/Keywords: biomedical engineering.; Major biomedical engineering.
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APA (6th Edition):
Lee, S. J. (2012). Near-infrared approaches for cell culture monitoring. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/ETD-TAMU-2003-THESIS-L443
Chicago Manual of Style (16th Edition):
Lee, Seung Joon. “Near-infrared approaches for cell culture monitoring.” 2012. Masters Thesis, Texas A&M University. Accessed April 15, 2021.
http://hdl.handle.net/1969.1/ETD-TAMU-2003-THESIS-L443.
MLA Handbook (7th Edition):
Lee, Seung Joon. “Near-infrared approaches for cell culture monitoring.” 2012. Web. 15 Apr 2021.
Vancouver:
Lee SJ. Near-infrared approaches for cell culture monitoring. [Internet] [Masters thesis]. Texas A&M University; 2012. [cited 2021 Apr 15].
Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2003-THESIS-L443.
Council of Science Editors:
Lee SJ. Near-infrared approaches for cell culture monitoring. [Masters Thesis]. Texas A&M University; 2012. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2003-THESIS-L443
Texas A&M University
19.
Shroff, Manish Vikram.
Isolated perfused working heart preparation for in vitro biomechanical studies.
Degree: MS, biomedical engineering, 2012, Texas A&M University
URL: http://hdl.handle.net/1969.1/ETD-TAMU-2003-THESIS-S408
► The isolated perfused working heart preparation has been an established method of investigation for larger animals. However, because of technical, economic and ethical issues, this…
(more)
▼ The isolated perfused working heart preparation has been an established method of investigation for larger animals. However, because of technical, economic and ethical issues, this methodology needs to be extended for use on mouse heart. Owing to their very small size, rapid heart rate, and different physiology, it was a challenge to modify this technique for mice. Increased evidence for the role of biomechanics in altered physiological states like cardiomyopathies have inspired the extension of using such a highly specialized technique for accessing biomechanical properties of normal (disease free) and diseased myocardium. A possible correlation can be shown using models of strain pattern in normal (disease free) as well as genetically engineered diseased states. In this study, one of the simplest biomechanical parameters, fractional shortening of left ventricular external diameter was computed. The preliminary findings of this in vitro mode of study were then compared to data from an established in vivo method of investigation, 2-D echocardiography. Using fractional shortening, a dimensionless property yielded a very close match, thereby establishing the efficacy of the system.
Subjects/Keywords: biomedical engineering.; Major biomedical engineering.
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APA (6th Edition):
Shroff, M. V. (2012). Isolated perfused working heart preparation for in vitro biomechanical studies. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/ETD-TAMU-2003-THESIS-S408
Chicago Manual of Style (16th Edition):
Shroff, Manish Vikram. “Isolated perfused working heart preparation for in vitro biomechanical studies.” 2012. Masters Thesis, Texas A&M University. Accessed April 15, 2021.
http://hdl.handle.net/1969.1/ETD-TAMU-2003-THESIS-S408.
MLA Handbook (7th Edition):
Shroff, Manish Vikram. “Isolated perfused working heart preparation for in vitro biomechanical studies.” 2012. Web. 15 Apr 2021.
Vancouver:
Shroff MV. Isolated perfused working heart preparation for in vitro biomechanical studies. [Internet] [Masters thesis]. Texas A&M University; 2012. [cited 2021 Apr 15].
Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2003-THESIS-S408.
Council of Science Editors:
Shroff MV. Isolated perfused working heart preparation for in vitro biomechanical studies. [Masters Thesis]. Texas A&M University; 2012. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2003-THESIS-S408
Texas A&M University
20.
Kotiya, Akhilesh A.
Development of a two dimensional optical fiber force transducer for constitutive modeling of soft tissue.
Degree: MS, biomedical engineering, 2012, Texas A&M University
URL: http://hdl.handle.net/1969.1/ETD-TAMU-2004-THESIS-K59
► Constitutive modeling of soft tissue has provided better understanding of their function and behavior in both normal and pathophysiological conditions. The ability to predict growth…
(more)
▼ Constitutive modeling of soft tissue has provided better understanding of their function and behavior in both normal and pathophysiological conditions. The ability to predict growth and remodeling of the tissue under the influence of applied mechanical loads suggests novel treatment methods for diseases like atherosclerosis, cardiac ischema, aneurysms, congestive heart failure and many others. Material properties such as anisotropy, nonlinearity, inhomogenity, and viscoelasticity make it difficult to characterize soft tissue. Biaxial testing (first suggested by Revlin) is an important tool to analyze nonlinear materials and biaxial testing devices have been widely used by bioengineers to develop constitutive models of soft tissue. The most broadly used model is that suggested by Y. C. Fung. Although a useful instrument, conventional biaxial testing devices suffer from certain limitations such as the inability to test small sized specimens, gripping techniques and its effects on behavior of tissue under biaxial loading state. Also the device cannot be used to perform shear tests on tissue and hence cannot be effectively used to model behavior of tissues like endocardium and myocardium that undergo large shear deformations under normal physiological conditions. The two-dimensional optical fiber force transducer aims at overcoming some of these limitations. Since the transducer can measure both axial and shear forces it can be used in fabricating devices capable of shear testing. Also the small size optical fibers make the transducers suitable to be used in instruments for testing small specimens. This work presents a theoretical design of such a transducer, its fabrication and calibration procedure, and its testing for accuracy and sensitivity.
Subjects/Keywords: biomedical engineering.; Major biomedical engineering.
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APA (6th Edition):
Kotiya, A. A. (2012). Development of a two dimensional optical fiber force transducer for constitutive modeling of soft tissue. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/ETD-TAMU-2004-THESIS-K59
Chicago Manual of Style (16th Edition):
Kotiya, Akhilesh A. “Development of a two dimensional optical fiber force transducer for constitutive modeling of soft tissue.” 2012. Masters Thesis, Texas A&M University. Accessed April 15, 2021.
http://hdl.handle.net/1969.1/ETD-TAMU-2004-THESIS-K59.
MLA Handbook (7th Edition):
Kotiya, Akhilesh A. “Development of a two dimensional optical fiber force transducer for constitutive modeling of soft tissue.” 2012. Web. 15 Apr 2021.
Vancouver:
Kotiya AA. Development of a two dimensional optical fiber force transducer for constitutive modeling of soft tissue. [Internet] [Masters thesis]. Texas A&M University; 2012. [cited 2021 Apr 15].
Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2004-THESIS-K59.
Council of Science Editors:
Kotiya AA. Development of a two dimensional optical fiber force transducer for constitutive modeling of soft tissue. [Masters Thesis]. Texas A&M University; 2012. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2004-THESIS-K59
Texas A&M University
21.
Balasubramanium, Prabaker.
Hybrid computer simulation of atomic orbitals of one electron system.
Degree: MS, biomedical engineering, 2012, Texas A&M University
URL: http://hdl.handle.net/1969.1/ETD-TAMU-1998-THESIS-B35
► An analog cum digital computing hybrid system is analyzed, to compare its speed of computation and accuracy with a full digital computer, for quantum chemical…
(more)
▼ An analog cum digital computing hybrid system is analyzed, to compare its speed of computation and accuracy with a full digital computer, for quantum chemical molecular modeling. This is done at the level of the simulation of the fundamental quantum chemical wave equation. Generating this function is the unit level operation in molecular modeling. Therefore, analyzing the performance of the hybrid computer at this level will bring out the basic differences between hybrid computing and digital computing for molecular modeling.
Subjects/Keywords: biomedical engineering.; Major biomedical engineering.
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APA (6th Edition):
Balasubramanium, P. (2012). Hybrid computer simulation of atomic orbitals of one electron system. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/ETD-TAMU-1998-THESIS-B35
Chicago Manual of Style (16th Edition):
Balasubramanium, Prabaker. “Hybrid computer simulation of atomic orbitals of one electron system.” 2012. Masters Thesis, Texas A&M University. Accessed April 15, 2021.
http://hdl.handle.net/1969.1/ETD-TAMU-1998-THESIS-B35.
MLA Handbook (7th Edition):
Balasubramanium, Prabaker. “Hybrid computer simulation of atomic orbitals of one electron system.” 2012. Web. 15 Apr 2021.
Vancouver:
Balasubramanium P. Hybrid computer simulation of atomic orbitals of one electron system. [Internet] [Masters thesis]. Texas A&M University; 2012. [cited 2021 Apr 15].
Available from: http://hdl.handle.net/1969.1/ETD-TAMU-1998-THESIS-B35.
Council of Science Editors:
Balasubramanium P. Hybrid computer simulation of atomic orbitals of one electron system. [Masters Thesis]. Texas A&M University; 2012. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-1998-THESIS-B35
Texas A&M University
22.
Cooney, Kevin Michael.
Investigation of infrared Fourier-Transform spectroscopy for oral cancer detection.
Degree: MS, biomedical engineering, 2012, Texas A&M University
URL: http://hdl.handle.net/1969.1/ETD-TAMU-1998-THESIS-C664
► A system was developed using a Fourier Transform-n spectrometer to investigate spectral differences between malignant, benign and healthy oral tissue in the near-infrared range (2.0-2.5…
(more)
▼ A system was developed using a Fourier Transform-n spectrometer to investigate spectral differences between malignant, benign and healthy oral tissue in the near-infrared range (2.0-2.5 microns). A hamster model for oral squamous cell carcinoma and one for benign lesions in soft oral tissue (i.e. inflammation) was used. After tissue transform-nation in the malignant and benign cases and when no transformation occurred (i.e. healthy), the animals were euthanized and the malignant, inflamed and healthy tissues were excised. Infrared absorption spectra of the buccal mucosa were then collected on all three models, in vitro. A total of 160 near-infrared (NIR) scans were taken, 70 on malignant tissue, 20 on benign, inflamed, tissue and 70 on healthy tissue. Multiplicative signal correction (MSC), used during preprocessing, together with principal component analysis (PCA) showed a 90% sensitivity, 87% specificity and a false negative rate of . 1 0 between malignant and healthy/benign tissue types across animals using this wavelength range. The eigenvectors from the PCA analysis indicate that differences were detectable in the 2.25-2.35 [mm range. Absorption spectra of different ratio mixtures of DNA/RNA and protein were studied to help identify which absorption bands were in this range. Small amounts of RNA were found to change the near-infrared absorption spectra significantly, when added to a mixture of DNA/protein. This leads to the conclusion that the concentration of RNA in the cell's nucleus may be a significant spectral marker in identifying malignant cells. Correlating the mixture's near-IR spectra with published information, the absorption bands in this range were found to be attributed to the N-H stretching, C=O stretching vibration, and C-H deformation vibrations. These molecular components can be found in the nucleotides of RNA and in the ribose sugar molecule.
Subjects/Keywords: biomedical engineering.; Major biomedical engineering.
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APA (6th Edition):
Cooney, K. M. (2012). Investigation of infrared Fourier-Transform spectroscopy for oral cancer detection. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/ETD-TAMU-1998-THESIS-C664
Chicago Manual of Style (16th Edition):
Cooney, Kevin Michael. “Investigation of infrared Fourier-Transform spectroscopy for oral cancer detection.” 2012. Masters Thesis, Texas A&M University. Accessed April 15, 2021.
http://hdl.handle.net/1969.1/ETD-TAMU-1998-THESIS-C664.
MLA Handbook (7th Edition):
Cooney, Kevin Michael. “Investigation of infrared Fourier-Transform spectroscopy for oral cancer detection.” 2012. Web. 15 Apr 2021.
Vancouver:
Cooney KM. Investigation of infrared Fourier-Transform spectroscopy for oral cancer detection. [Internet] [Masters thesis]. Texas A&M University; 2012. [cited 2021 Apr 15].
Available from: http://hdl.handle.net/1969.1/ETD-TAMU-1998-THESIS-C664.
Council of Science Editors:
Cooney KM. Investigation of infrared Fourier-Transform spectroscopy for oral cancer detection. [Masters Thesis]. Texas A&M University; 2012. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-1998-THESIS-C664
Texas A&M University
23.
Merchant, Jean Carol.
Optical low coherence reflectometry for the measurement of collagen thickness.
Degree: MS, biomedical engineering, 2012, Texas A&M University
URL: http://hdl.handle.net/1969.1/ETD-TAMU-1998-THESIS-M473
► The objective of this research project was to accurately measure changes in collagen thickness with a Michelson interferometry system. The system consists of a reference…
(more)
▼ The objective of this research project was to accurately measure changes in collagen thickness with a Michelson interferometry system. The system consists of a reference interferometer with a laser source and a measurement interferometer with a low coherence length source. There are several important components of the system which are necessary for achieving accurate measurements. Some of those components include a high SNR, uniform translation and a narrow measurement beam size. While the system developed was able to measure collagen thickness, the accuracy could be drastically improved by increasing the SNR, translating the reference mirrors uniformly and a smaller measurement beam size. The system was able to measure the thickness of ablated and non-ablated collagen despite a low SNR, non-uniform translation and a large beam diameter.
Subjects/Keywords: biomedical engineering.; Major biomedical engineering.
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APA (6th Edition):
Merchant, J. C. (2012). Optical low coherence reflectometry for the measurement of collagen thickness. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/ETD-TAMU-1998-THESIS-M473
Chicago Manual of Style (16th Edition):
Merchant, Jean Carol. “Optical low coherence reflectometry for the measurement of collagen thickness.” 2012. Masters Thesis, Texas A&M University. Accessed April 15, 2021.
http://hdl.handle.net/1969.1/ETD-TAMU-1998-THESIS-M473.
MLA Handbook (7th Edition):
Merchant, Jean Carol. “Optical low coherence reflectometry for the measurement of collagen thickness.” 2012. Web. 15 Apr 2021.
Vancouver:
Merchant JC. Optical low coherence reflectometry for the measurement of collagen thickness. [Internet] [Masters thesis]. Texas A&M University; 2012. [cited 2021 Apr 15].
Available from: http://hdl.handle.net/1969.1/ETD-TAMU-1998-THESIS-M473.
Council of Science Editors:
Merchant JC. Optical low coherence reflectometry for the measurement of collagen thickness. [Masters Thesis]. Texas A&M University; 2012. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-1998-THESIS-M473
Texas A&M University
24.
Pickard, Julie Marie.
An interactive three-dimensional computer graphic simulation of the upper extremity.
Degree: MS, biomedical engineering, 2012, Texas A&M University
URL: http://hdl.handle.net/1969.1/ETD-TAMU-1998-THESIS-P53
► A three-dimensional computer graphic simulation which hics. allows for the arbitrary placement of axes of motion with respect to skeletal structures is described. The simulation,…
(more)
▼ A three-dimensional computer graphic simulation which hics. allows for the arbitrary placement of axes of motion with respect to skeletal structures is described. The simulation, developed on a Sum UItraSPARC high performance workstation integrated with an Evans and Sutherland graphics accelerator, uses OpenGL and C programming software within the UNIX X Windows environment. The three-dimensional bone structures are triangular polygons derived from computerized tomography scans. Each axis of rotation is represented symbolically by a long narrow cylindrical tube with a wire sphere located at its midpoint. The bony structures can be rotated around these axes. This thesis develops the foundation of the computer program, a three-dimensional, interactive, kinematic, real-time, computer graphic simulation of the upper extremity skeletal structures that allows for the arbitrary orientation and placement of up to three independent axes of rotation for each joint.
Subjects/Keywords: biomedical engineering.; Major biomedical engineering.
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APA (6th Edition):
Pickard, J. M. (2012). An interactive three-dimensional computer graphic simulation of the upper extremity. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/ETD-TAMU-1998-THESIS-P53
Chicago Manual of Style (16th Edition):
Pickard, Julie Marie. “An interactive three-dimensional computer graphic simulation of the upper extremity.” 2012. Masters Thesis, Texas A&M University. Accessed April 15, 2021.
http://hdl.handle.net/1969.1/ETD-TAMU-1998-THESIS-P53.
MLA Handbook (7th Edition):
Pickard, Julie Marie. “An interactive three-dimensional computer graphic simulation of the upper extremity.” 2012. Web. 15 Apr 2021.
Vancouver:
Pickard JM. An interactive three-dimensional computer graphic simulation of the upper extremity. [Internet] [Masters thesis]. Texas A&M University; 2012. [cited 2021 Apr 15].
Available from: http://hdl.handle.net/1969.1/ETD-TAMU-1998-THESIS-P53.
Council of Science Editors:
Pickard JM. An interactive three-dimensional computer graphic simulation of the upper extremity. [Masters Thesis]. Texas A&M University; 2012. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-1998-THESIS-P53
Texas A&M University
25.
Enloe, Lillian Charity.
Application of smoothing algorithms to enhance quality of 3D reconstructed images in tissues and cultures.
Degree: MS, biomedical engineering, 2012, Texas A&M University
URL: http://hdl.handle.net/1969.1/ETD-TAMU-1999-THESIS-E74
► Visualization of scientific data plays an ever increasingly vital role in the study of humans, plants, animals, and the world around us. An integral part…
(more)
▼ Visualization of scientific data plays an ever increasingly vital role in the study of humans, plants, animals, and the world around us. An integral part of that visualization and what makes it possible is the use of modern technology, specifically computers. Computers give scientists and engineers freedom to study and manipulate a sample as often as necessary in order to understand its characteristices while only requiring them to sample a specimen and record data once. This has afforded a great opportunity for lending and testing different conditions and the effects of different stimuli with minimal intrusion and damage to the original human, plant, or animal from which the specimen was acquired. To that end, the focus of this research is to apply this very efficient, effective tool to smooth 3D reconstructed images of test spheres and plant cells. In order to reconstruct a series of segmented images in 3D it is necessary to use the Marching Cubes algorithm which takes a specified scalar value and uses it to construct a 3D surface called an isosurface from the information contained within the segmented images. There is a variety of software packages currently on the market that use this algorithm as part of their functionality. However, few are as efficient, effective, low cost, and easy to use as the Visualization Toolkit developed by Bill Lorensen, Will Schroeder and Ken Martin. One distinct advantage to using the Visualization Toolkit (VTK) as a tool is that it was created with the help of the original developer of the Marching Cubes algorithm, Bill Lorenesen. VTK offers a low cost, easy to use method of accomplishing very sophisticated postprocessing of images without the need for extensive programming or high end computers such as mainframes.
Subjects/Keywords: biomedical engineering.; Major biomedical engineering.
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APA (6th Edition):
Enloe, L. C. (2012). Application of smoothing algorithms to enhance quality of 3D reconstructed images in tissues and cultures. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/ETD-TAMU-1999-THESIS-E74
Chicago Manual of Style (16th Edition):
Enloe, Lillian Charity. “Application of smoothing algorithms to enhance quality of 3D reconstructed images in tissues and cultures.” 2012. Masters Thesis, Texas A&M University. Accessed April 15, 2021.
http://hdl.handle.net/1969.1/ETD-TAMU-1999-THESIS-E74.
MLA Handbook (7th Edition):
Enloe, Lillian Charity. “Application of smoothing algorithms to enhance quality of 3D reconstructed images in tissues and cultures.” 2012. Web. 15 Apr 2021.
Vancouver:
Enloe LC. Application of smoothing algorithms to enhance quality of 3D reconstructed images in tissues and cultures. [Internet] [Masters thesis]. Texas A&M University; 2012. [cited 2021 Apr 15].
Available from: http://hdl.handle.net/1969.1/ETD-TAMU-1999-THESIS-E74.
Council of Science Editors:
Enloe LC. Application of smoothing algorithms to enhance quality of 3D reconstructed images in tissues and cultures. [Masters Thesis]. Texas A&M University; 2012. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-1999-THESIS-E74
Texas A&M University
26.
Krishnamoorthy, Gayathri.
Functional role of tropomyosin on thin filament activation and cross bridge kinetics in transgenic cardiac muscle: a model study.
Degree: MS, biomedical engineering, 2012, Texas A&M University
URL: http://hdl.handle.net/1969.1/ETD-TAMU-1999-THESIS-K76
► Regulation of contractile activity in cardiac muscle is a cooperative interaction between thick and thin filament sarcomeric proteins. Tropomyosin (Tm), an essential thin filament protein,…
(more)
▼ Regulation of contractile activity in cardiac muscle is a cooperative interaction between thick and thin filament sarcomeric proteins. Tropomyosin (Tm), an essential thin filament protein, interacts with troponin (Tn) and regulates muscle contraction in a Ca²⁺-dependent manner. Striated muscle-specific α-Tm isoform is the predominant isoform in the adult vertebrate heart, while both α- and β-Tm striated isoform are present in skeletal muscles. Studies have shown that exchange of myofibrillar proteins can be achieved via a single kakogenic manipulation with no change in the stoichiometry of myofibrillar proteins. One of the mouse models with exchange of β-Tm for α-Tm demonstrates that altering the ratio of α- and β-Tm leads to physiological change in myocardial relaxation and increases Ca²⁺ sensitivity myofilaments. In addition, reduction in maximum force and ATPase activity in this transgenic mouse model suggests no change in the rate-limiting step of cross-bridge detachment. To further understand the mechanisms of how Tm isoform population modulates cardiac muscle dynamics, this study uses a modeling approach. Although existing models address thin filament activation and cross-bridge kinetics, cooperative interactions among myofibrillar proteins have not been explicitly demonstrated. In this study, Tn, Tm and actin are introduced as three different variables to analyze thin filament activation and cross-bridge cycling. The model is initially tested for normal output using data from literature obtained from in vitro and in vivo experiments. Using this model and data obtained from β-Tm transgenic mouse experiments, key parameters that determine functional alteration in the kakogenic mouse hearts are identified. Results show that increased calcium sensitivity and decreased maximum force in β-Tm transgenic mouse hearts is due to increased capability of strong cross-bridges in activating the thin filament and decreased rate of attachment of myosin heads to actin.
Subjects/Keywords: biomedical engineering.; Major biomedical engineering.
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APA (6th Edition):
Krishnamoorthy, G. (2012). Functional role of tropomyosin on thin filament activation and cross bridge kinetics in transgenic cardiac muscle: a model study. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/ETD-TAMU-1999-THESIS-K76
Chicago Manual of Style (16th Edition):
Krishnamoorthy, Gayathri. “Functional role of tropomyosin on thin filament activation and cross bridge kinetics in transgenic cardiac muscle: a model study.” 2012. Masters Thesis, Texas A&M University. Accessed April 15, 2021.
http://hdl.handle.net/1969.1/ETD-TAMU-1999-THESIS-K76.
MLA Handbook (7th Edition):
Krishnamoorthy, Gayathri. “Functional role of tropomyosin on thin filament activation and cross bridge kinetics in transgenic cardiac muscle: a model study.” 2012. Web. 15 Apr 2021.
Vancouver:
Krishnamoorthy G. Functional role of tropomyosin on thin filament activation and cross bridge kinetics in transgenic cardiac muscle: a model study. [Internet] [Masters thesis]. Texas A&M University; 2012. [cited 2021 Apr 15].
Available from: http://hdl.handle.net/1969.1/ETD-TAMU-1999-THESIS-K76.
Council of Science Editors:
Krishnamoorthy G. Functional role of tropomyosin on thin filament activation and cross bridge kinetics in transgenic cardiac muscle: a model study. [Masters Thesis]. Texas A&M University; 2012. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-1999-THESIS-K76
Texas A&M University
27.
Lewis, Christopher Bryan.
Investigation of near-infrared spectroscopy for periodic in situ cell culture media determination of glucose and lactate.
Degree: MS, biomedical engineering, 2012, Texas A&M University
URL: http://hdl.handle.net/1969.1/ETD-TAMU-1999-THESIS-L47
► Current techniques used to monitor glucose concentration of cell culture media require invasive and tedious handling of the sample for sterile media removal and nutrient…
(more)
▼ Current techniques used to monitor glucose concentration of cell culture media require invasive and tedious handling of the sample for sterile media removal and nutrient replacement. In order to maximize cell culture growth in bioreactors, biosensors must be developed that are capable of monitoring the cell culture processes non-invasively and continuously. Non-invasive determinations of glucose and lactate in cell culture media were investigated via near-infrared spectroscopy (NIR) across the 2.0-2.5 []m combination region. A system was developed using a Fourier Transform Infrared (FHR) spectrometer to characterize glucose and lactate single beam spectra collected from cell culture media. Spectra recorded from a three-day fibroblast culture using a fiber-optic coupled culture flask with an FTIR spectrometer have been analyzed and compared with standard clinical chemistry techniques. Partial least squares regression has been used to extract the analyte-dependent information and to build a successful multivariate calibration model. Calibration, using a combination of spectra from cell culture media and prepared media mixtures, was performed and applied to an independent validation set, resulting in a prediction error of 14.8 mg/dl. Critical parameters surround the application of NIR spectroscopy to most biologically based samples, such as cell culture media. In addition to temperature and humidity, pH stability plays an essential role in the investigator's ability to accurately quantify concentrations of analyses of interest. It has been shown here that absorbable spectra of glucose may drastically deviate from "normal'' in the presence of pH-varying sample and a pH-constant reference spectrum. Because cell culture ranges of PH extend beyond the comparatively tight control of human physiological pH, it was necessary to seek out these implications and report them. For quantification studies, results indicate that potential interference due to varying pH values must be accounted for.
Subjects/Keywords: biomedical engineering.; Major biomedical engineering.
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APA (6th Edition):
Lewis, C. B. (2012). Investigation of near-infrared spectroscopy for periodic in situ cell culture media determination of glucose and lactate. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/ETD-TAMU-1999-THESIS-L47
Chicago Manual of Style (16th Edition):
Lewis, Christopher Bryan. “Investigation of near-infrared spectroscopy for periodic in situ cell culture media determination of glucose and lactate.” 2012. Masters Thesis, Texas A&M University. Accessed April 15, 2021.
http://hdl.handle.net/1969.1/ETD-TAMU-1999-THESIS-L47.
MLA Handbook (7th Edition):
Lewis, Christopher Bryan. “Investigation of near-infrared spectroscopy for periodic in situ cell culture media determination of glucose and lactate.” 2012. Web. 15 Apr 2021.
Vancouver:
Lewis CB. Investigation of near-infrared spectroscopy for periodic in situ cell culture media determination of glucose and lactate. [Internet] [Masters thesis]. Texas A&M University; 2012. [cited 2021 Apr 15].
Available from: http://hdl.handle.net/1969.1/ETD-TAMU-1999-THESIS-L47.
Council of Science Editors:
Lewis CB. Investigation of near-infrared spectroscopy for periodic in situ cell culture media determination of glucose and lactate. [Masters Thesis]. Texas A&M University; 2012. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-1999-THESIS-L47
Texas A&M University
28.
Misri, Sandeep.
Model for a web based communication system between clinical engineers and medical device companies.
Degree: MS, biomedical engineering, 2012, Texas A&M University
URL: http://hdl.handle.net/1969.1/ETD-TAMU-1999-THESIS-M577
► The Internet and its use is proliferating. Many medical device manufacturers have their own web sites where they provide useful, but not standardized information about…
(more)
▼ The Internet and its use is proliferating. Many medical device manufacturers have their own web sites where they provide useful, but not standardized information about their products and services. Similarly hospitals and clinics also have Web sites that can be accessed for information related to their services, and clinical engineers commonly have Web access. The missing link in this scenario is a Web site that could act as a central point of coned between the clinical engineers and the device manufacturers. Due to huge numbers of both, an elective means of a 'many to many' interaction between the two is presently not available. This project proposes a model of a communication system between clinical engineers and medical device manufacturers based on Internet technologies and relational databases. This model attempts to bridge the communication gap and provide an effective means of information dissemination between device manufacturers and clinical engineers.
Subjects/Keywords: biomedical engineering.; Major biomedical engineering.
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APA (6th Edition):
Misri, S. (2012). Model for a web based communication system between clinical engineers and medical device companies. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/ETD-TAMU-1999-THESIS-M577
Chicago Manual of Style (16th Edition):
Misri, Sandeep. “Model for a web based communication system between clinical engineers and medical device companies.” 2012. Masters Thesis, Texas A&M University. Accessed April 15, 2021.
http://hdl.handle.net/1969.1/ETD-TAMU-1999-THESIS-M577.
MLA Handbook (7th Edition):
Misri, Sandeep. “Model for a web based communication system between clinical engineers and medical device companies.” 2012. Web. 15 Apr 2021.
Vancouver:
Misri S. Model for a web based communication system between clinical engineers and medical device companies. [Internet] [Masters thesis]. Texas A&M University; 2012. [cited 2021 Apr 15].
Available from: http://hdl.handle.net/1969.1/ETD-TAMU-1999-THESIS-M577.
Council of Science Editors:
Misri S. Model for a web based communication system between clinical engineers and medical device companies. [Masters Thesis]. Texas A&M University; 2012. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-1999-THESIS-M577
Texas A&M University
29.
O'Neal, Dennis Patrick Doucet.
The application of surface-enhanced Raman spectroscopy for the detection of excitatory amino acids.
Degree: MS, biomedical engineering, 2012, Texas A&M University
URL: http://hdl.handle.net/1969.1/ETD-TAMU-1999-THESIS-O54
► The release of excitatory amino acids (EAAs) from injured neurons has been associated with secondary injury following head trauma. The development of a rapid and…
(more)
▼ The release of excitatory amino acids (EAAs) from injured neurons has been associated with secondary injury following head trauma. The development of a rapid and sensitive method for the quantification of EAAs may provide a novel means for clinical management of patients affected by head trauma. Of the amino acids L-glutamic (Glu) and L-aspartic acid (Asp), the concentration of Glu is more indicative of injury to the central nervous system. This study explores the detection limit of Glu using surface enhanced Raman spectroscopy (SERS) on aqueous silver colloids. This study examines methods to monitor the colloidal reactions for the calibration of the enhancement observed. Thirty second Raman spectral scans were taken utilizing a 50 mW argon laser. Isolated aqueous Glu was quantifiable from 0.4 []mol/L - 5 []mol/L from an examination of a unique spectral feature at 830cm⁻¹. Asp exhibits a unique but comparable shifted spectral feature at 785cm⁻¹ using the same probing parameters. In order to test this technique in vivo, rat extracellular brain fluid microanalysis samples were collected before and after a localized brain infarct was produced using a middle cerebral artery occlusion (MCAO). SERS spectral analysis of these samples showed an intriguing correlation with expected changes in EAA levels as influenced by the MCAO damage model. We show that SERS techniques may have the promise of providing the sensitivity and selectivity required to quantify EAAs in a phantom medium at physiological concentrations. Compared with conventional detection techniques such as high performance liquid chromatography, this research employs no sample preparation techniques, thus reducing assay time. The controlled studies and limited animal studies suggest that the SERS technique described here may become a viable prelude for providing diagnostic information about nervous system injury in anticipation of clinical intervention.
Subjects/Keywords: biomedical engineering.; Major biomedical engineering.
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APA (6th Edition):
O'Neal, D. P. D. (2012). The application of surface-enhanced Raman spectroscopy for the detection of excitatory amino acids. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/ETD-TAMU-1999-THESIS-O54
Chicago Manual of Style (16th Edition):
O'Neal, Dennis Patrick Doucet. “The application of surface-enhanced Raman spectroscopy for the detection of excitatory amino acids.” 2012. Masters Thesis, Texas A&M University. Accessed April 15, 2021.
http://hdl.handle.net/1969.1/ETD-TAMU-1999-THESIS-O54.
MLA Handbook (7th Edition):
O'Neal, Dennis Patrick Doucet. “The application of surface-enhanced Raman spectroscopy for the detection of excitatory amino acids.” 2012. Web. 15 Apr 2021.
Vancouver:
O'Neal DPD. The application of surface-enhanced Raman spectroscopy for the detection of excitatory amino acids. [Internet] [Masters thesis]. Texas A&M University; 2012. [cited 2021 Apr 15].
Available from: http://hdl.handle.net/1969.1/ETD-TAMU-1999-THESIS-O54.
Council of Science Editors:
O'Neal DPD. The application of surface-enhanced Raman spectroscopy for the detection of excitatory amino acids. [Masters Thesis]. Texas A&M University; 2012. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-1999-THESIS-O54
Texas A&M University
30.
Piper, James Clarice.
Radiation interchange modeling for active infrared proximity sensor design.
Degree: MS, biomedical engineering, 2012, Texas A&M University
URL: http://hdl.handle.net/1969.1/ETD-TAMU-1999-THESIS-P57
► The objective of this research was to create mathematical models suitable for use in the design and operation of active optical proximity sensors based on…
(more)
▼ The objective of this research was to create mathematical models suitable for use in the design and operation of active optical proximity sensors based on infrared optoelectronic components. Computer simulation using Monte Carlo techniques, and based on principles from the field of radiometry, was used to model the optical interaction occurring in selected sensor applications. The data from these simulations were then used to create models relating sensor data to environmental parameters. This research focuses on information gathered using active optical proximity sensors in the reflectance sensing mode. The portion of energy reflected to a given sensor in combination with the known location of the source and sensor elements provide the basic information used to evaluate the target characteristics. Simulation studies were conducted to examine the effects of varying target reflectance, size, and position using a spherical target, and the effect of varying angle was examined using a cylindrical target. The targets were simulated as having uniform surface properties irrespective of radiation spectrum, being perfect reflectors, and varying in only one aspect for a given study. Analysis began with graphical examination of trends from both the perspective of an individual sensor over multiple data points and over all sensors for an individual data point. In the reflectance, size, and angle studies the target parameters were related to the sensor data by individual sensor using least squares polynomial curve fitting. Subsequently, the effect of distance between source and sensor was incorporated by applying nonlinear polynomial curve fitting to the coefficients of the individual sensor polynomial fit equations to form an overall composite equation fit for each study. In the position study algorithmic approaches were applied to the determination of target location using data from multiple sensors. The primary findings suggest that a single source and sensor may be adequate for determination of target reflectance, size, position, or angle provided only one degree of freedom exists in the problem presented. Determination of position in three dimensional space or more than one target characteristic requires assessment of multiple unknowns, thereby necessitating the use of multiple source elements, sensor elements, or both.
Subjects/Keywords: biomedical engineering.; Major biomedical engineering.
Record Details
Similar Records
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Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Piper, J. C. (2012). Radiation interchange modeling for active infrared proximity sensor design. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/ETD-TAMU-1999-THESIS-P57
Chicago Manual of Style (16th Edition):
Piper, James Clarice. “Radiation interchange modeling for active infrared proximity sensor design.” 2012. Masters Thesis, Texas A&M University. Accessed April 15, 2021.
http://hdl.handle.net/1969.1/ETD-TAMU-1999-THESIS-P57.
MLA Handbook (7th Edition):
Piper, James Clarice. “Radiation interchange modeling for active infrared proximity sensor design.” 2012. Web. 15 Apr 2021.
Vancouver:
Piper JC. Radiation interchange modeling for active infrared proximity sensor design. [Internet] [Masters thesis]. Texas A&M University; 2012. [cited 2021 Apr 15].
Available from: http://hdl.handle.net/1969.1/ETD-TAMU-1999-THESIS-P57.
Council of Science Editors:
Piper JC. Radiation interchange modeling for active infrared proximity sensor design. [Masters Thesis]. Texas A&M University; 2012. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-1999-THESIS-P57
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