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University of Adelaide
1.
Ding, Boyin.
A study of a Gough-Stewart platform-based manipulator for applications in biomechanical testing.
Degree: 2014, University of Adelaide
URL: http://hdl.handle.net/2440/92664
► This thesis investigates the development and application of a robotic system for in-vitro biomechanical testing to study the mechanisms leading to human joint injury and…
(more)
▼ This thesis investigates the development and application of a robotic system for in-vitro
biomechanical testing to study the mechanisms leading to human joint injury and degeneration in an ethical and safe manner. Six degree of freedom (6-DOF) robotic-based systems, in particular Gough-Stewart platform-based systems, have been increasingly used in applications of
biomechanical testing where 6-DOF mobility, large load capacity, and high stiffness and positioning accuracy are required from the
testing machine. This study proposes a novel Gough-Stewart platform-based manipulator with ultra-high stiffness and accuracy for use in
biomechanical testing and investigates its mechanism and control. Not only restricted to
biomechanical testing, the proposed manipulator concept can also be applied to other robotic-based applications, particularly those requiring ultra-high accuracy positioning under large external loads (e.g machining). Four main features of the proposed manipulator are individually studied in this thesis: namely, stiffness and control of a non-collocated actuator-sensor mechanism, active preload control using actuation redundancy for backlash elimination, adaptive velocity-based load control of human joints for unconstrained
testing, and reproducing the in-vivo measured kinematics on human cadaveric joints. Stiffness and Control of the Non-collocated Actuator-Sensor Mechanism A novel Gough-Stewart platform-based mechanism is proposed with a fully decoupled actuator-sensor arrangement for passively compensating the structural compliance of the manipulator. The stiffness of the robot load frame and the sensing frame are respectively quantified using the robot kinematics error model combined with finite element analysis (FEA) on the top and bottom assemblies. Numerical results demonstrate that the proposed mechanism improves the stiffness of the robotic
testing system in excess of an order of magnitude on the translational axes and two orders of magnitude for rotational axes compared to a traditional actuator-sensor collocated design. Control disturbances arising from actuator-sensor non-collocation is addressed using decoupled control. Experimental results show that the proposed decoupled control algorithm improves the dynamic accuracy of the manipulator by approximately 25% on average. Active Preload Control Using Actuation Redundancy for Backlash Elimination This thesis investigates combining the benefits of both active and passive preload control methods, using actuation redundancy to prevent backlash on a general Gough- Stewart platform. Both the mechanical configuration and the dynamics model of the redundant manipulator are investigated for the ease of control. A novel online optimization algorithm combined with a feedback force control scheme is formulated to achieve a real-time method which is robust to both model inaccuracy and load disturbance. Simulation results demonstrate an effective preload efficacy by the redundant arrangement within the workspace of the robot. Simulation results also show that…
Advisors/Committee Members: Cazzolato, Benjamin Seth (advisor), Costi, John Jack (advisor), Grainger, Steven Drummond (advisor), School of Mechanical Engineering (school).
Subjects/Keywords: Stewart platform; biomechanical testing; control
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
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APA (6th Edition):
Ding, B. (2014). A study of a Gough-Stewart platform-based manipulator for applications in biomechanical testing. (Thesis). University of Adelaide. Retrieved from http://hdl.handle.net/2440/92664
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Ding, Boyin. “A study of a Gough-Stewart platform-based manipulator for applications in biomechanical testing.” 2014. Thesis, University of Adelaide. Accessed January 23, 2021.
http://hdl.handle.net/2440/92664.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Ding, Boyin. “A study of a Gough-Stewart platform-based manipulator for applications in biomechanical testing.” 2014. Web. 23 Jan 2021.
Vancouver:
Ding B. A study of a Gough-Stewart platform-based manipulator for applications in biomechanical testing. [Internet] [Thesis]. University of Adelaide; 2014. [cited 2021 Jan 23].
Available from: http://hdl.handle.net/2440/92664.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Ding B. A study of a Gough-Stewart platform-based manipulator for applications in biomechanical testing. [Thesis]. University of Adelaide; 2014. Available from: http://hdl.handle.net/2440/92664
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
2.
Caquías, Daniela Fabiana Izquierdo.
Desenvolvimento e avaliação biomecânica da resistência à flexão de um novo modelo de osteossíntese em fêmur: pinos intramedulares múltiplos bloqueados.
Degree: Mestrado, Clínica Cirúrgica Veterinária, 2010, University of São Paulo
URL: http://www.teses.usp.br/teses/disponiveis/10/10137/tde-09022011-110541/
;
► Na atualidade, vários são os métodos de osteossíntese utilizados na reparação de fraturas de fêmur em cães, porém alguns apresentam complicações na técnica, e outros…
(more)
▼ Na atualidade, vários são os métodos de osteossíntese utilizados na reparação de fraturas de fêmur em cães, porém alguns apresentam complicações na técnica, e outros não encontram-se disponíveis na atividade profissional diária de alguns médicos veterinários da América Latina. O presente trabalho teve como objetivo desenvolver um novo modelo simples de osteossíntese, baseado na utilização de pinos de Steinmann e Schanz denominado pinos intramedulares múltiplos bloqueados (PIMB), e testar biomecanicamente a resistência as forças de flexão em comparação com a técnica de pino intramedular único (PIU). Para tanto foram utilizados fêmures bilaterais de oito cadáveres de cães com peso entre 15 a 25 quilos que foram divididos em dois grupos, o primeiro grupo composto por oito fêmures utilizou os pinos intramedulares múltiplos bloqueados e o segundo grupo composto por oito fêmures utilizou pino intramedular único, ocupando entre 40 - 42 % do canal medular como controle do Grupo 1. Os dois grupos de fêmures foram submetidos a ensaios não destrutivos para avaliar a resistência as forças de flexão, com forças entre 0 e 50 Kg, e velocidade de deslocamento de 5mm/minuto, num dispositivo de quatro pontos. Os resultados encontrados nas condições apresentadas neste estudo mostraram que a técnica de pinos intramedulares múltiplos bloqueados apresenta uma menor resistência as forças de flexão comparada com a técnica de pino intramedular único
Currently, there are several methods of fixation used in the repair of femoral fractures in dogs, but some show complications in the technique, and others are not available daily in the professional activity of some veterinarians from Latin America. This study aimed the development of a new, simple model for bone fixation, based on the use of Steinmann and threaded pins, used as multiple locked intramedullary pins (MLIP), and biomechanically test the implants resistance to bending forces. Therefore, we used bilateral femurs of eight cadaveric dogs weighing between 15-25 kg, divided into two groups; in the first group multiple locked intramedullary pins were used in eight femurs, and in the second group, the control group, we used a single intramedullary pin (SIP) occupying between 40-42% of the intramedullary canal, of eight femurs. Both groups were subjected, in a four point device, to nondestructive testing to evaluate the resistance to flexion forces, with forces varying between 0 and 50 kg, and a speed of 5mm/minute. The results under the conditions presented in this study showed that technique locked multiple pins has a lower resistance to bending forces compared with the technique of single intramedullary pin.
Advisors/Committee Members: Ferrigno, Cássio Ricardo Auada.
Subjects/Keywords: Biomechanical testing; Cães; Dogs; Ensaio Biomecânico; Fêmur; Fêmur; Fracture; Fratura
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APA ·
Chicago ·
MLA ·
Vancouver ·
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to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Caquías, D. F. I. (2010). Desenvolvimento e avaliação biomecânica da resistência à flexão de um novo modelo de osteossíntese em fêmur: pinos intramedulares múltiplos bloqueados. (Masters Thesis). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/10/10137/tde-09022011-110541/ ;
Chicago Manual of Style (16th Edition):
Caquías, Daniela Fabiana Izquierdo. “Desenvolvimento e avaliação biomecânica da resistência à flexão de um novo modelo de osteossíntese em fêmur: pinos intramedulares múltiplos bloqueados.” 2010. Masters Thesis, University of São Paulo. Accessed January 23, 2021.
http://www.teses.usp.br/teses/disponiveis/10/10137/tde-09022011-110541/ ;.
MLA Handbook (7th Edition):
Caquías, Daniela Fabiana Izquierdo. “Desenvolvimento e avaliação biomecânica da resistência à flexão de um novo modelo de osteossíntese em fêmur: pinos intramedulares múltiplos bloqueados.” 2010. Web. 23 Jan 2021.
Vancouver:
Caquías DFI. Desenvolvimento e avaliação biomecânica da resistência à flexão de um novo modelo de osteossíntese em fêmur: pinos intramedulares múltiplos bloqueados. [Internet] [Masters thesis]. University of São Paulo; 2010. [cited 2021 Jan 23].
Available from: http://www.teses.usp.br/teses/disponiveis/10/10137/tde-09022011-110541/ ;.
Council of Science Editors:
Caquías DFI. Desenvolvimento e avaliação biomecânica da resistência à flexão de um novo modelo de osteossíntese em fêmur: pinos intramedulares múltiplos bloqueados. [Masters Thesis]. University of São Paulo; 2010. Available from: http://www.teses.usp.br/teses/disponiveis/10/10137/tde-09022011-110541/ ;

Laurentian University
3.
Omri, Karim.
Design, construction and validation of internal organ phantoms for biomechanical testing
.
Degree: 2013, Laurentian University
URL: https://zone.biblio.laurentian.ca/dspace/handle/10219/2092
► This thesis includes the development, construction and testing of internal organ phantoms, with focus on the liver, for biomechanical testing. Phantoms have various biomedical applications…
(more)
▼ This thesis includes the development, construction and testing of internal organ
phantoms, with focus on the liver, for biomechanical testing. Phantoms have various
biomedical applications such as surgical simulations, minimally invasive surgery, soft
tissue characterization, diagnostic tools and instrumentation calibration. However, there
is little work present in literature regarding phantoms and the work that is currently
available does not account for the non-linear viscoelastic properties as well as the
Glisson’s capsule. In this work, three different phantoms are presented: a fluid-filled
phantom, a perfused phantom and a hydrogel-based liver phantom. A testing apparatus is
designed, built and used to measure the force-displacement data during the indentation of
the phantom.
The first phantom that is designed and constructed follows the basis of a fluid-filled
vessel. It is composed of a linear low-density polyethylene (LLDPE) bag filled with
different fluids namely: water, a 1:1 water/glycerine mixture and glycerine. The
phantoms are subjected to quasi-static loading as well as relaxation testing. The effect of
density and viscosity, its size, and confined and unconfined boundary conditions are
characterized.
The second phantom is designed to investigate the effects of hepatic macrocirculation on
the biomechanical properties of the liver. The phantom is made of two-part silicone
(Smooth-On, ECOFLEX 00-30), and contains a network of conduits to model the large
! iv!
blood vessels in the liver. A perfusion system that captures the general features of the
human hepatic circulation is used to help investigate the effects of the different flow
parameters such as pressure and flow rate on the biomechanical characteristics of the
liver. The perfusion system is designed to reproduce comparable pressures to the human
portal vein and hepatic artery.
The third phantom is made of two parts, a hydrogel inner layer with a LLDPE outer layer.
The idea behind this phantom is to represent the organ as accurately as possible by
accounting for the capsule that surrounds the organ as well as the biphasic (solid and
fluid) nature of the organ. A biphasic poroviscoelastic model is used to model the
hydrogel while the LLDPE uses a non-linear hyperelastic and viscoelastic model.
Modeling is done in ABAQUS to fit the experimental data obtained from quasi-static
indentation and relaxation testing using a parametric study.
In conclusion, phantoms replicating the non-linear viscoelastic properties observed in
organs are presented and characterized.
Main Thesis Contributions
• Development and characterization of a simple fluid-filled phantom to represent
the mechanical properties of the liver
• Development and characterization of hydrogel-based liver phantom with
representation of the biphasic nature of the organ and the Glisson’s capsule.
! v!
• Development and characterization of perfused liver phantom with ability to be recreated
with various vessel configurations.
• Development of testing…
Subjects/Keywords: Internal organ phantoms;
Construction;
Biomechanical testing for the liver
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Omri, K. (2013). Design, construction and validation of internal organ phantoms for biomechanical testing
. (Thesis). Laurentian University. Retrieved from https://zone.biblio.laurentian.ca/dspace/handle/10219/2092
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Omri, Karim. “Design, construction and validation of internal organ phantoms for biomechanical testing
.” 2013. Thesis, Laurentian University. Accessed January 23, 2021.
https://zone.biblio.laurentian.ca/dspace/handle/10219/2092.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Omri, Karim. “Design, construction and validation of internal organ phantoms for biomechanical testing
.” 2013. Web. 23 Jan 2021.
Vancouver:
Omri K. Design, construction and validation of internal organ phantoms for biomechanical testing
. [Internet] [Thesis]. Laurentian University; 2013. [cited 2021 Jan 23].
Available from: https://zone.biblio.laurentian.ca/dspace/handle/10219/2092.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Omri K. Design, construction and validation of internal organ phantoms for biomechanical testing
. [Thesis]. Laurentian University; 2013. Available from: https://zone.biblio.laurentian.ca/dspace/handle/10219/2092
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
4.
Bonsignore, Lindsay Ann.
SURFACE CONTAMINANTS INHIBIT THE OSSEOINTEGRATION OF
ORTHOPAEDIC IMPLANTS.
Degree: PhD, Pathology, 2012, Case Western Reserve University School of Graduate Studies
URL: http://rave.ohiolink.edu/etdc/view?acc_num=case1341323221
► The most important factor contributing to short-term and long-term success of cementless total joint arthroplasties is osseointegration. Osseointegration is the process by which a direct…
(more)
▼ The most important factor contributing to short-term
and long-term success of cementless total joint arthroplasties is
osseointegration. Osseointegration is the process by which a direct
structural and functional connection between living bone and the
surface of an implant is made. Surface contaminants may remain on
orthopaedic implants after sterilization procedures and impair
osseointegration. For example, specific lots of hip replacement
Sulzer Inter-OPTM acetabular shells that were associated with
impaired osseointegration and early failure rates were found to be
contaminated with both bacterial debris and machine oil residues.
However, few osseointegration studies have focused on surface
contaminants and their effect on implant integration is unknown.
Therefore, we developed a novel murine model that provides
quantitative and reproducible measurements of osseointegration to
study the effect of surface contaminants. We found that a rigorous
cleaning procedure significantly enhances osseointegration compared
to implants that were autoclaved. The most likely interpretation of
these results is that surface contaminants on the autoclaved
implants inhibit osseointegration. Using our murine model, we also
found that Gram-negative bacterial derived LPS or machine oil
residues on implants inhibit osseointegration. Ultrapure LPS
adherent to titanium alloy discs had no detectable effect on early
stages of MC3T3-E1 osteogenesis in vitro such as attachment,
spreading or growth but inhibited later stages of osteogenic
differentiation and mineralization. In contrast, machine oil on
titanium alloy discs inhibited osteoblast attachment, spreading,
growth, differentiation and mineralization in vitro. These results
demonstrate that both adherent LPS and machine oil can
significantly impair osseointegration through direct effects on
osteoblasts; however, they do so by inhibiting distinct steps in
the process. The presence of both LPS and machine oil could lead to
synergistic impairment of osseointegration, which may account for
the impaired osseointegration in the failed lots of Sulzer
Inter-OPTM implants. These results highlight bacterial debris and
machine oil as types of surface contaminants that can impair the
osseointegration of orthopaedic implants. In addition, these
results justify the need for the development of better detection
and removal techniques for contaminants on orthopaedic
implants.
Advisors/Committee Members: Greenfield, Edward (Advisor), Anderson, James (Committee Chair).
Subjects/Keywords: Biomedical Research; orthopaedics; osseointegration; surface contaminants; biomechanical testing; histomorphometry; lipopolysaccharide
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Bonsignore, L. A. (2012). SURFACE CONTAMINANTS INHIBIT THE OSSEOINTEGRATION OF
ORTHOPAEDIC IMPLANTS. (Doctoral Dissertation). Case Western Reserve University School of Graduate Studies. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=case1341323221
Chicago Manual of Style (16th Edition):
Bonsignore, Lindsay Ann. “SURFACE CONTAMINANTS INHIBIT THE OSSEOINTEGRATION OF
ORTHOPAEDIC IMPLANTS.” 2012. Doctoral Dissertation, Case Western Reserve University School of Graduate Studies. Accessed January 23, 2021.
http://rave.ohiolink.edu/etdc/view?acc_num=case1341323221.
MLA Handbook (7th Edition):
Bonsignore, Lindsay Ann. “SURFACE CONTAMINANTS INHIBIT THE OSSEOINTEGRATION OF
ORTHOPAEDIC IMPLANTS.” 2012. Web. 23 Jan 2021.
Vancouver:
Bonsignore LA. SURFACE CONTAMINANTS INHIBIT THE OSSEOINTEGRATION OF
ORTHOPAEDIC IMPLANTS. [Internet] [Doctoral dissertation]. Case Western Reserve University School of Graduate Studies; 2012. [cited 2021 Jan 23].
Available from: http://rave.ohiolink.edu/etdc/view?acc_num=case1341323221.
Council of Science Editors:
Bonsignore LA. SURFACE CONTAMINANTS INHIBIT THE OSSEOINTEGRATION OF
ORTHOPAEDIC IMPLANTS. [Doctoral Dissertation]. Case Western Reserve University School of Graduate Studies; 2012. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=case1341323221

Boise State University
5.
Krentz, Madison Elizabeth.
High-Cycle Fatigue Life of Human Meniscus.
Degree: 2018, Boise State University
URL: https://scholarworks.boisestate.edu/td/1483
► The meniscus is a soft fibrous tissue that distributes cyclic loads across the knee joint. It is frequently injured, and one likely mechanism for failure…
(more)
▼ The meniscus is a soft fibrous tissue that distributes cyclic loads across the knee joint. It is frequently injured, and one likely mechanism for failure is repeated exposure to low-magnitude loads, known as high-cycle fatigue. When a tear occurs, it causes a disruption of function, leading to swelling and pain, as well as an increase in the likelihood of development of osteoarthritis by six-fold. Though meniscus tears due to fatigue are clinically relevant, the fatigue properties of meniscus are poorly understood. In fact, current literature only describes fatigue properties of bovine meniscus up to 20,000 cycles at stress levels much higher than daily loading activities. This research aims to fill the gap in knowledge regarding high-cycle fatigue properties of human meniscus through three steps: 1) develop a test procedure that reduces the incidence of invalid clampsite failures, 2) perform quasi-static tests to correlate the ultimate tensile strength (UTS) of human meniscus to linear modulus, and 3) perform tension-tension fatigue testing at 20%, 35% and 55% of the predicted UTS until failure or a maximum of one million cycles is reached.
A test procedure was successfully developed that eliminated clamp site failures in 95% of meniscus tensile tests. This test procedure used specimen geometry based on ASTM test standards and used innovative cutting techniques to improve the tolerance of specimen width and thickness. The quasi-static tensile testing of meniscus from donors under 40 years old resulted in a good correlation between linear modulus and UTS (R2 = 0.75). Also, regional variability in material properties was present when comparing the anterior medial meniscus (UTS = 24.5 ± 2.6 MPa) to the posterior medial meniscus (UTS = 7.9 ± 4.9 MPa). Fatigue tests of human meniscus under 40 years old resulted in an average creep rate of 0.02% per 1000 cycles, and an average total creep of 2.4 mm for specimens that failed in fatigue. Results from the S-N curve indicated a strong log-linear correlation for fatigue life (R2=0.99). Interestingly, specimens tested at 20% UTS and one specimen tested at 35% UTS reached the maximum one million cycles without failing. For below 30% UTS, median fatigue failure was estimated to occur after 30 million cycles. This suggests that meniscus may have an effective endurance limit below 30% UTS. The creation of the S-N curve allows for cycles to failure estimations to be made based on applied stress during cyclic activities such as walking or running. Future work includes performing fatigue tests on human meniscus over 65 years old to determine the effect of age-related changes in the extracellular matrix on fatigue life.
Subjects/Keywords: fatigue testing; meniscus; soft tissue; test preparation; mechanical testing; Biomechanical Engineering; Biomedical Engineering and Bioengineering
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Krentz, M. E. (2018). High-Cycle Fatigue Life of Human Meniscus. (Thesis). Boise State University. Retrieved from https://scholarworks.boisestate.edu/td/1483
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Krentz, Madison Elizabeth. “High-Cycle Fatigue Life of Human Meniscus.” 2018. Thesis, Boise State University. Accessed January 23, 2021.
https://scholarworks.boisestate.edu/td/1483.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Krentz, Madison Elizabeth. “High-Cycle Fatigue Life of Human Meniscus.” 2018. Web. 23 Jan 2021.
Vancouver:
Krentz ME. High-Cycle Fatigue Life of Human Meniscus. [Internet] [Thesis]. Boise State University; 2018. [cited 2021 Jan 23].
Available from: https://scholarworks.boisestate.edu/td/1483.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Krentz ME. High-Cycle Fatigue Life of Human Meniscus. [Thesis]. Boise State University; 2018. Available from: https://scholarworks.boisestate.edu/td/1483
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
6.
Latorre, Carlos Adolfo Salazar.
Artrodese da articulação interfalangeana proximal de equinos: avaliação biomecânica comparativa da técnica com placa de compressão dinâmica de 4,5mm e três orifícios, com dois parafusos transarticulares oblíquos de 5,5mm e técnica com placa \"Y\" de compressão bloqueada de 5,0mm e sete orifícios.
Degree: Mestrado, Clínica Cirúrgica Veterinária, 2013, University of São Paulo
URL: http://www.teses.usp.br/teses/disponiveis/10/10137/tde-22112013-122140/
;
► As claudicações são a principal causa de encaminhamento de equinos aos médicos veterinários e uma das maiores causas de encaminhamento destes animais aos hospitais de…
(more)
▼ As claudicações são a principal causa de encaminhamento de equinos aos médicos veterinários e uma das maiores causas de encaminhamento destes animais aos hospitais de referência; sendo as fraturas, especialmente aquelas de ossos longos e articulares, as que têm menor índice de sucesso devido ao prognóstico reservado e alto custo do tratamento; entendendo como sucesso o retorno do animal à função ou manutenção da qualidade de vida. A articulação interfalangeana proximal (AIP) dos equinos é clinicamente importante devido à apresentação frequente de claudicação, com lesões que comprometem a vida esportiva e função do equino. O objetivo desta pesquisa foi comparar biomecanicamente as características de duas técnicas de artrodese da AIP em equinos, utilizando-se placa de compressão dinâmica (DCP) de 4.5mm e três orifícios em combinação com dois parafusos corticais transarticulares de 5.5mm oblíquos inseridos pela técnica de tração (lag screw) e placa em "Yd̈e compressão bloqueada (LCP) de 5,0mm e sete orifícios, com parafusos bloquados unicorticais e um parafuso cortical de 4.5mm oblíquo transarticular inserido no orifício central da placa, pela técnica de parafuso de tração. Foram utilizadas doze peças anatômicas de membros anteriores de equinos, das quais foi isolada a porção distal do membro desde a primeira falange até o casco. Uma vez preparadas as peças, cada par foi sorteado randomicamente para cada um dos dois grupos. Os modelos experimentais foram submetidos a ensaios biomecânicos de compressão axial em ciclo único até a sua falha. O tipo de falha ocorrida na placa, nos parafusos ou nos ossos foi avaliado, assim como a força à qual ocorreram estas falhas. Não houve diferença estatística significativa entre os grupos DCP e Y-LCP, nas variáveis rigidez e força máxima, quando submetidas a compressão axial até sua falha. Mesmo não havendo diferença entre as duas técnicas cirúrgicas na variável rigidez, a técnica Y-LCP possibilitou um procedimento menos invasivo e com menor tempo cirúrgico. Conclui-se que, as propriedades biomecânicas das duas técnicas de fixação (DCP e Y-LCP) são semelhantes nas condições testadas.
Lameness is the main cause of sport horsesówners consulting equine veterinarians and one of the highest cause to send these animals to the reference hospitals. Long bones and joint fractures have the lesser rate of success, consequence of the hight cost of the treatment and poor prognosis. Understanding as success the return of the horse to previous athletic performance or at least to have useful life. The proximal interphalangeal joint (PIPJ) is clinically important because the injuries that involve it may threaten the horses sport life or its usefulness. The objective of this study was to compare the biomechanical properties of two PIPJ arthrodesis techniques using 4.5mm dynamic compression plate (DCP) in conjunction with two oblique abaxial transarticular 5.5mm cortical screws inserted in lag fashion and 5.0mm Y locking compression plate (Y-LCP) with unicortical locking screws and one axial…
Advisors/Committee Members: Zoppa, André Luis do Valle de.
Subjects/Keywords: Axial compression; Biomechanical testing; Compressão axial; Ensaio biomecânico; Parafusos bloqueados unicorticais; Unicortical locking screws
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❌
APA ·
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MLA ·
Vancouver ·
CSE |
Export
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Manager
APA (6th Edition):
Latorre, C. A. S. (2013). Artrodese da articulação interfalangeana proximal de equinos: avaliação biomecânica comparativa da técnica com placa de compressão dinâmica de 4,5mm e três orifícios, com dois parafusos transarticulares oblíquos de 5,5mm e técnica com placa \"Y\" de compressão bloqueada de 5,0mm e sete orifícios. (Masters Thesis). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/10/10137/tde-22112013-122140/ ;
Chicago Manual of Style (16th Edition):
Latorre, Carlos Adolfo Salazar. “Artrodese da articulação interfalangeana proximal de equinos: avaliação biomecânica comparativa da técnica com placa de compressão dinâmica de 4,5mm e três orifícios, com dois parafusos transarticulares oblíquos de 5,5mm e técnica com placa \"Y\" de compressão bloqueada de 5,0mm e sete orifícios.” 2013. Masters Thesis, University of São Paulo. Accessed January 23, 2021.
http://www.teses.usp.br/teses/disponiveis/10/10137/tde-22112013-122140/ ;.
MLA Handbook (7th Edition):
Latorre, Carlos Adolfo Salazar. “Artrodese da articulação interfalangeana proximal de equinos: avaliação biomecânica comparativa da técnica com placa de compressão dinâmica de 4,5mm e três orifícios, com dois parafusos transarticulares oblíquos de 5,5mm e técnica com placa \"Y\" de compressão bloqueada de 5,0mm e sete orifícios.” 2013. Web. 23 Jan 2021.
Vancouver:
Latorre CAS. Artrodese da articulação interfalangeana proximal de equinos: avaliação biomecânica comparativa da técnica com placa de compressão dinâmica de 4,5mm e três orifícios, com dois parafusos transarticulares oblíquos de 5,5mm e técnica com placa \"Y\" de compressão bloqueada de 5,0mm e sete orifícios. [Internet] [Masters thesis]. University of São Paulo; 2013. [cited 2021 Jan 23].
Available from: http://www.teses.usp.br/teses/disponiveis/10/10137/tde-22112013-122140/ ;.
Council of Science Editors:
Latorre CAS. Artrodese da articulação interfalangeana proximal de equinos: avaliação biomecânica comparativa da técnica com placa de compressão dinâmica de 4,5mm e três orifícios, com dois parafusos transarticulares oblíquos de 5,5mm e técnica com placa \"Y\" de compressão bloqueada de 5,0mm e sete orifícios. [Masters Thesis]. University of São Paulo; 2013. Available from: http://www.teses.usp.br/teses/disponiveis/10/10137/tde-22112013-122140/ ;
7.
Jabran, Ali.
Biomechanical Analysis of Proximal Humerus Plate for
Spatial Subchondral Support.
Degree: 2018, University of Manchester
URL: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:312920
► Proximal humerus fractures are the third most common fractures in the over-65 patient population and their stable fixation remains a key challenge in orthopaedic and…
(more)
▼ Proximal humerus fractures are the third most
common fractures in the over-65 patient population and their stable
fixation remains a key challenge in orthopaedic and trauma surgery.
While Open Reduction Internal Fixation by plate has become a
well-known treatment modality in the last few decades, clinical
studies associate high complication rate with its use. The overall
aim of this project was to create a computer-aided design framework
for proximal humerus plates using a validated
subject-specific
humerus-plate finite element model. The framework consisted of
three stages: (1) reverse engineering of bone and plate geometry,
(2) creation and validation of a finite element model simulating
the in vitro
testing of the bone-implant construct and (3)
parametric optimisation study of implant design using this model.
In vitro
biomechanical tests were conducted to not only compare the
mechanical performance of three key commercially available proximal
humerus plates (S3-, Fx- and PHILOS plate) but also the effect of
different screw zones. Sixty-five humeri specimens with two-part
surgical neck fractures were treated and grouped based on their
different screw configurations. Extension, flexion, varus and
valgus bending were applied in the cantilever fashion in the
elastic tests whereas only varus bending was applied in the plastic
tests. The load required to apply 5 mm displacement was measured to
determine bone-plate construct stiffness. The S3 plate yielded the
stiffest constructs and while the removal of the inferomedial
support had the most impact on varus bending stiffness, type of
medial support was important: inferomedial screws in the Fx plate
achieved higher bending stiffness than blade insertion. Stability
of constructs treated with the plate was an interplay of factors
such as the plate’s and screws' number, orientation and position.
Next, a
subject-specific finite element model of the humerus-plate
construct was successfully developed that simulated the stiffest of
the constructs from the in vitro varus bending tests conducted in
this project. The model was validated against the in vitro results.
The validated model was then used to perform a parametric
optimisation study where the combination of design parameters
(height and divergence angle of S3 plate’s inferomedial screws)
was determined that achieved optimum bone-plate construct stability
(minimum fracture gap change). Out of the 538 designs tested, the
optimum design (16o divergence angle and 33o height angle) yielded
the lowest fracture gap change (0.156 mm) which was 4.686% lower
than the standard finite element model while achieving 5.707%
higher varus bending load (54.753 N). The validated model was also
used to investigate the issue of using smooth pegs and threaded
screws. Twenty-six models with different percentages of screw
threading were run to compare their bone-plate construct stiffness.
While threading the smooth pegs was found to increase the varus
bending stiffness by up to 4.546%, it did not affect all screws
equally. Finally, the…
Advisors/Committee Members: ZOU, ZHENMIN Z, Ren, Lei, Zou, Zhenmin.
Subjects/Keywords: Biomechanical Testing; Proximal Humerus; Locking Plates; Finite Element Analysis; Design Optimization; Orthopedic Design
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Jabran, A. (2018). Biomechanical Analysis of Proximal Humerus Plate for
Spatial Subchondral Support. (Doctoral Dissertation). University of Manchester. Retrieved from http://www.manchester.ac.uk/escholar/uk-ac-man-scw:312920
Chicago Manual of Style (16th Edition):
Jabran, Ali. “Biomechanical Analysis of Proximal Humerus Plate for
Spatial Subchondral Support.” 2018. Doctoral Dissertation, University of Manchester. Accessed January 23, 2021.
http://www.manchester.ac.uk/escholar/uk-ac-man-scw:312920.
MLA Handbook (7th Edition):
Jabran, Ali. “Biomechanical Analysis of Proximal Humerus Plate for
Spatial Subchondral Support.” 2018. Web. 23 Jan 2021.
Vancouver:
Jabran A. Biomechanical Analysis of Proximal Humerus Plate for
Spatial Subchondral Support. [Internet] [Doctoral dissertation]. University of Manchester; 2018. [cited 2021 Jan 23].
Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:312920.
Council of Science Editors:
Jabran A. Biomechanical Analysis of Proximal Humerus Plate for
Spatial Subchondral Support. [Doctoral Dissertation]. University of Manchester; 2018. Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:312920
8.
Jabran, Ali.
Biomechanical analysis of proximal humerus plate for spatial subchondral support.
Degree: PhD, 2017, University of Manchester
URL: https://www.research.manchester.ac.uk/portal/en/theses/biomechanical-analysis-of-proximal-humerus-plate-for-spatial-subchondral-support(101d8da0-ce24-44c0-9ca1-8fe281b3e7fd).html
;
https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.740293
► Proximal humerus fractures are the third most common fractures in the over-65 patient population and their stable fixation remains a key challenge in orthopaedic and…
(more)
▼ Proximal humerus fractures are the third most common fractures in the over-65 patient population and their stable fixation remains a key challenge in orthopaedic and trauma surgery. While Open Reduction Internal Fixation by plate has become a well-known treatment modality in the last few decades, clinical studies associate high complication rate with its use. The overall aim of this project was to create a computer-aided design framework for proximal humerus plates using a validated subject-specific humerus-plate finite element model. The framework consisted of three stages: (1) reverse engineering of bone and plate geometry, (2) creation and validation of a finite element model simulating the in vitro testing of the bone-implant construct and (3) parametric optimisation study of implant design using this model. In vitro biomechanical tests were conducted to not only compare the mechanical performance of three key commercially available proximal humerus plates (S3-, Fx- and PHILOS plate) but also the effect of different screw zones. Sixty-five humeri specimens with two-part surgical neck fractures were treated and grouped based on their different screw configurations. Extension, flexion, varus and valgus bending were applied in the cantilever fashion in the elastic tests whereas only varus bending was applied in the plastic tests. The load required to apply 5 mm displacement was measured to determine bone-plate construct stiffness. The S3 plate yielded the stiffest constructs and while the removal of the inferomedial support had the most impact on varus bending stiffness, type of medial support was important: inferomedial screws in the Fx plate achieved higher bending stiffness than blade insertion. Stability of constructs treated with the plate was an interplay of factors such as the plateâs and screws' number, orientation and position. Next, a subject-specific finite element model of the humerus-plate construct was successfully developed that simulated the stiffest of the constructs from the in vitro varus bending tests conducted in this project. The model was validated against the in vitro results. The validated model was then used to perform a parametric optimisation study where the combination of design parameters (height and divergence angle of S3 plateâs inferomedial screws) was determined that achieved optimum bone-plate construct stability (minimum fracture gap change). Out of the 538 designs tested, the optimum design (16o divergence angle and 33o height angle) yielded the lowest fracture gap change (0.156 mm) which was 4.686% lower than the standard finite element model while achieving 5.707% higher varus bending load (54.753 N). The validated model was also used to investigate the issue of using smooth pegs and threaded screws. Twenty-six models with different percentages of screw threading were run to compare their bone-plate construct stiffness. While threading the smooth pegs was found to increase the varus bending stiffness by up to 4.546%, it did not affect all screws equally. Finally, the…
Subjects/Keywords: 610.28; Design Optimization; Orthopedic Design; Finite Element Analysis; Proximal Humerus; Biomechanical Testing; Locking Plates
Record Details
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Record Details
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Jabran, A. (2017). Biomechanical analysis of proximal humerus plate for spatial subchondral support. (Doctoral Dissertation). University of Manchester. Retrieved from https://www.research.manchester.ac.uk/portal/en/theses/biomechanical-analysis-of-proximal-humerus-plate-for-spatial-subchondral-support(101d8da0-ce24-44c0-9ca1-8fe281b3e7fd).html ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.740293
Chicago Manual of Style (16th Edition):
Jabran, Ali. “Biomechanical analysis of proximal humerus plate for spatial subchondral support.” 2017. Doctoral Dissertation, University of Manchester. Accessed January 23, 2021.
https://www.research.manchester.ac.uk/portal/en/theses/biomechanical-analysis-of-proximal-humerus-plate-for-spatial-subchondral-support(101d8da0-ce24-44c0-9ca1-8fe281b3e7fd).html ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.740293.
MLA Handbook (7th Edition):
Jabran, Ali. “Biomechanical analysis of proximal humerus plate for spatial subchondral support.” 2017. Web. 23 Jan 2021.
Vancouver:
Jabran A. Biomechanical analysis of proximal humerus plate for spatial subchondral support. [Internet] [Doctoral dissertation]. University of Manchester; 2017. [cited 2021 Jan 23].
Available from: https://www.research.manchester.ac.uk/portal/en/theses/biomechanical-analysis-of-proximal-humerus-plate-for-spatial-subchondral-support(101d8da0-ce24-44c0-9ca1-8fe281b3e7fd).html ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.740293.
Council of Science Editors:
Jabran A. Biomechanical analysis of proximal humerus plate for spatial subchondral support. [Doctoral Dissertation]. University of Manchester; 2017. Available from: https://www.research.manchester.ac.uk/portal/en/theses/biomechanical-analysis-of-proximal-humerus-plate-for-spatial-subchondral-support(101d8da0-ce24-44c0-9ca1-8fe281b3e7fd).html ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.740293

University of Guelph
9.
Brett, Allan.
Biomechanical Properties of the Transverse Carpal Ligament.
Degree: Master of Applied Science, School of Engineering, 2013, University of Guelph
URL: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/7496
► The mechanical properties of the transverse carpal ligament (TCL) have yet to be comprehensively measured. Failure strain, failure load, ultimate strength, stiffness and elastic modulus…
(more)
▼ The mechanical properties of the transverse carpal ligament (TCL) have yet to be comprehensively measured. Failure strain, failure load, ultimate strength, stiffness and elastic modulus were reported from uniaxial tensile tests. On human cadaveric TCLs, failure strain was significantly higher in female specimens compared to males. Moreover, regional strain analysis showed the lateral end of the tissue to strain significantly more than the medial. Biaxial
testing at three different tissue depths was also carried out. Mechanical properties were found to vary significantly by depth with the deeper layers displaying higher mechanical properties. A significant difference with respect to loading direction was also observed with the medial/lateral direction displaying higher mechanical properties than proximal/distal. These results provide mechanical properties which can be incorporated into finite element models or constitutive models of the TCL. Furthermore, this work provides a basis for recommendations for non-invasive treatment options for carpal tunnel syndrome.
Advisors/Committee Members: Gordon, Karen (advisor).
Subjects/Keywords: transverse carpal ligament (syn: flexor retunaculum); carpal tunnel syndrome; biomechanical properties; biaxial testing
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Brett, A. (2013). Biomechanical Properties of the Transverse Carpal Ligament. (Masters Thesis). University of Guelph. Retrieved from https://atrium.lib.uoguelph.ca/xmlui/handle/10214/7496
Chicago Manual of Style (16th Edition):
Brett, Allan. “Biomechanical Properties of the Transverse Carpal Ligament.” 2013. Masters Thesis, University of Guelph. Accessed January 23, 2021.
https://atrium.lib.uoguelph.ca/xmlui/handle/10214/7496.
MLA Handbook (7th Edition):
Brett, Allan. “Biomechanical Properties of the Transverse Carpal Ligament.” 2013. Web. 23 Jan 2021.
Vancouver:
Brett A. Biomechanical Properties of the Transverse Carpal Ligament. [Internet] [Masters thesis]. University of Guelph; 2013. [cited 2021 Jan 23].
Available from: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/7496.
Council of Science Editors:
Brett A. Biomechanical Properties of the Transverse Carpal Ligament. [Masters Thesis]. University of Guelph; 2013. Available from: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/7496

University of Arkansas
10.
Srinivasan Venkatesh, Balaji.
Development of a PDMS Based Micro Total Analysis System for Rapid Biomolecule Detection.
Degree: PhD, 2013, University of Arkansas
URL: https://scholarworks.uark.edu/etd/594
► The emerging field of micro total analysis system powered by microfluidics is expected to revolutionize miniaturization and automation for point-of-care-testing systems which require quick,…
(more)
▼ The emerging field of micro total analysis system powered by microfluidics is expected to revolutionize miniaturization and automation for point-of-care-
testing systems which require quick, efficient and reproducible results. In the present study, a PDMS based micro total analysis system has been developed for rapid, multi-purpose, impedance based detection of biomolecules. The major components of the micro total analysis system include a micropump, micromixer, magnetic separator and interdigitated electrodes for impedance detection. Three designs of pneumatically actuated PDMS based micropumps were fabricated and tested. Based on the performance test results, one of the micropumps was selected for integration. The experimental results of the micropump performance were confirmed by a 2D COMSOL simulation combined with an equivalent circuit analysis of the micropump. Three designs of pneumatically actuated PDMS based active micromixers were fabricated and tested. The micromixer
testing involved determination of mixing efficiency based on the streptavidin-biotin conjugation reaction between biotin comjugated fluorescent microbeads and streptavidin conjugated paramagnetic microbeads, followed by fluorescence measurements. Based on the performance test results, one of the micromixers was selected for integration. The selected micropump and micromixer were integrated into a single microfluidic system. The
testing of the magnetic separation scheme involved comparison of three permanent magnets and three electromagnets of different sizes and magnetic strengths, for capturing magnetic microbeads at various flow rates. Based on the test results, one of the permanent magnets was selected. The interdigitated electrodes were fabricated on a glass substrate with gold as the electrode material. The selected micropumps, micromixer and interdigitated electrodes were integrated to achieve a fully integrated microfluidic system. The fully integrated microfluidic system was first applied towards biotin conjugated fluorescent microbeads detection based on streptavidin-biotin conjugation reaction which is followed by impedance spectrum measurements. The lower detection limit for biotin conjugated fluorescent microbeads was experimentally determined to be 1.9 x 106 microbeads. The fully integrated microfluidic system was then applied towards immuno microbead based insulin detection. The lower detection limit for insulin was determined to be 10-5M. The total detection time was 20 min. An equivalent circuit analysis was performed to explain the impedance spectrum results.
Advisors/Committee Members: Chao-Hung Steve Tung, Yanbin Li, Douglas E. Spearot.
Subjects/Keywords: Applied sciences; Biomolecule detection; Microfluidics; PDMS; Point-of-care-testing; Biomechanical Engineering; Electro-Mechanical Systems
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Srinivasan Venkatesh, B. (2013). Development of a PDMS Based Micro Total Analysis System for Rapid Biomolecule Detection. (Doctoral Dissertation). University of Arkansas. Retrieved from https://scholarworks.uark.edu/etd/594
Chicago Manual of Style (16th Edition):
Srinivasan Venkatesh, Balaji. “Development of a PDMS Based Micro Total Analysis System for Rapid Biomolecule Detection.” 2013. Doctoral Dissertation, University of Arkansas. Accessed January 23, 2021.
https://scholarworks.uark.edu/etd/594.
MLA Handbook (7th Edition):
Srinivasan Venkatesh, Balaji. “Development of a PDMS Based Micro Total Analysis System for Rapid Biomolecule Detection.” 2013. Web. 23 Jan 2021.
Vancouver:
Srinivasan Venkatesh B. Development of a PDMS Based Micro Total Analysis System for Rapid Biomolecule Detection. [Internet] [Doctoral dissertation]. University of Arkansas; 2013. [cited 2021 Jan 23].
Available from: https://scholarworks.uark.edu/etd/594.
Council of Science Editors:
Srinivasan Venkatesh B. Development of a PDMS Based Micro Total Analysis System for Rapid Biomolecule Detection. [Doctoral Dissertation]. University of Arkansas; 2013. Available from: https://scholarworks.uark.edu/etd/594

Vanderbilt University
11.
Weis, Jared Anthony.
A Novel Finite Element Inverse Analysis to Assess Bone Fracture Healing.
Degree: PhD, Biomedical Engineering, 2011, Vanderbilt University
URL: http://hdl.handle.net/1803/13877
► Assessment of the restoration of load-bearing function is the central goal in the study of bone fracture healing. However, bone fracture calluses are inhomogeneous and…
(more)
▼ Assessment of the restoration of load-bearing function is the central goal in the study of bone fracture healing. However, bone fracture calluses are inhomogeneous and irregular materials and this complexity has led to considerable uncertainty in the assessment of
biomechanical property improvement or impairment during various therapeutic interventions and genetic models of pathological fracture healing. Unfortunately, as a result, arguably one of the most important criteria, mechanical stability, is the least resolved with respect to fracture healing assessment. To address this issue, an inverse finite element analysis (FEA) approach was developed in which
biomechanical testing and microCT imaging are integrated through the use of computational modeling to determine mechanical properties of the healing fracture callus tissue. The presented work serves to evaluate the inverse analysis as a functional fracture healing assessment methodology in comparison to more traditional imaging and
biomechanical testing measures within the context of normal fracture healing and a therapeutic system involving mesenchymal stem cell (MSC) transplantation. As compared to traditional fracture healing metrics, the results demonstrate that the inverse FEA approach: (1) was the only metric to successfully detect both longitudinal and therapeutic responses, and (2) performed significantly better at late-stage healing time points, where traditional metrics failed. The inverse analysis also added insight to the role of MSCs in fracture healing by demonstrating both accelerated healing and therapeutic benefit at late-stage healing. Additionally, a systems-based approach was developed for the generation of ease-of-use enhancements to the inverse analysis methodology in order to facilitate a wider usage among bone fracture biology groups whom are not experts in computational analysis. This was accomplished by the construction of an online web-enabled model submission system in which bone fracture callus microCT imaging and
biomechanical testing data are collected with a minimal amount of pre-processing on a remote user node and submitted to a compute node which builds and executes the inverse model for material property reconstruction. In conclusion, the inverse FEA approach is shown to be a sensitive and functional fracture healing measure and provides a significant first-step towards normalizing the often challenging process of assessing mechanical integrity of healing fractures.
Advisors/Committee Members: Craig Duvall (committee member), Hak-Joon Sung (committee member), John Gore (committee member), Anna Spagnoli (committee member), Michael Miga (Committee Chair).
Subjects/Keywords: mesenchymal stem cells; finite element analysis; mechanical properties; biomechanical testing; microCT; bone fracture healing
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Weis, J. A. (2011). A Novel Finite Element Inverse Analysis to Assess Bone Fracture Healing. (Doctoral Dissertation). Vanderbilt University. Retrieved from http://hdl.handle.net/1803/13877
Chicago Manual of Style (16th Edition):
Weis, Jared Anthony. “A Novel Finite Element Inverse Analysis to Assess Bone Fracture Healing.” 2011. Doctoral Dissertation, Vanderbilt University. Accessed January 23, 2021.
http://hdl.handle.net/1803/13877.
MLA Handbook (7th Edition):
Weis, Jared Anthony. “A Novel Finite Element Inverse Analysis to Assess Bone Fracture Healing.” 2011. Web. 23 Jan 2021.
Vancouver:
Weis JA. A Novel Finite Element Inverse Analysis to Assess Bone Fracture Healing. [Internet] [Doctoral dissertation]. Vanderbilt University; 2011. [cited 2021 Jan 23].
Available from: http://hdl.handle.net/1803/13877.
Council of Science Editors:
Weis JA. A Novel Finite Element Inverse Analysis to Assess Bone Fracture Healing. [Doctoral Dissertation]. Vanderbilt University; 2011. Available from: http://hdl.handle.net/1803/13877

Universidade do Rio Grande do Sul
12.
Corrêa, Daniel dos Santos.
Realidade virtual e sensores inerciais no desenvolvimento da tecnologia assistiva : um sistema para estudo da marcha humana baseado em fusão de sensores inerciais.
Degree: 2015, Universidade do Rio Grande do Sul
URL: http://hdl.handle.net/10183/149951
► A marcha humana, ou caminhada, é um padrão cíclico de movimentos corporais que se repetem a cada passo que desloca um indivíduo de um local…
(more)
▼ A marcha humana, ou caminhada, é um padrão cíclico de movimentos corporais que se repetem a cada passo que desloca um indivíduo de um local a outro. Atualmente, avaliações biomecânicas da marcha humana tem sido utilizado no diagnóstico de alterações neuromusculares, músculo-esqueléticas e como forma de avaliação pré e pós-tratamento cirúrgico, medicamentoso e/ou fisioterapêutico. O presente trabalho apresenta o desenvolvimento de uma ferramenta acadêmica de baixo custo para o estudo da marcha humana. Esse sistema consiste no sensoriamento da marcha de um usuário através de sensores inerciais e de um modelo virtual do corpo humano para permitir a visualização do movimento gerado. Dessa maneira o usuário poderá ter suas ações corrigidas por sua percepção visual e também corrigida pelas orientações de um fisiatra ou fisioterapeuta que terá a reprodução do modelo virtual conforme a movimentação detalhada do paciente para análise. O sistema ainda efetuará os registros das variáveis cinemáticas da marcha (tais como aceleração, velocidade angular, angulações dos membros sensoriados) para estudos e acompanhamento mais detalhado da sua recuperação e/ou tratamento. Como resultado, o sistema desenvolvido obteve erros médios de X 0,52º Y 1,20º Z 1,80º e erros em RMS de X 3,01º Y 3,30º Z 5,70º quando comparados com um sistema comercial, sendo esse resultado próximo à literatura e aplicável em exames biomecânicos de marcha.
The human gait is a cyclical pattern of body movements that are repeated every step that moves a subject from one location to another. Currently, biomechanical assessments of human gait has been used for diagnosing neuromuscular disorders, musculoskeletal and as a way of pre and post-surgical treatment, medication and/or physical therapy. This paper presents the development of a low cost academic tool for the study of human gait. This system consists of sensing the motion of a user through inertial sensors and a virtual model of the human body to allow the visualization of the generated movement. In this way, the user can have its actions corrected by his visual perception and also corrected by therapist or physiotherapist who will visualize the virtual model as the detailed movements of patient. The system will also record the kinematic gait variables (as acceleration, angular velocity, angles of the sensed members) for studies and more detailed monitoring of their recovery and/or treatment. As result, the developed system obtained average errors of X 0,52º Y 1,20º Z 1,80º and errors in RMS X 3,01º Y 3,30º Z 5,70º compared to a commercial system, and these results close to the ones seen in literature and applicable in biomechanical tests of gait.
Advisors/Committee Members: Balbinot, Alexandre.
Subjects/Keywords: Inertial sensors; Biomecânica; Movimento humano; Biomechanical testing; Redes sem fio; Human gait; Sensor inercial; Virtual model
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Corrêa, D. d. S. (2015). Realidade virtual e sensores inerciais no desenvolvimento da tecnologia assistiva : um sistema para estudo da marcha humana baseado em fusão de sensores inerciais. (Thesis). Universidade do Rio Grande do Sul. Retrieved from http://hdl.handle.net/10183/149951
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Corrêa, Daniel dos Santos. “Realidade virtual e sensores inerciais no desenvolvimento da tecnologia assistiva : um sistema para estudo da marcha humana baseado em fusão de sensores inerciais.” 2015. Thesis, Universidade do Rio Grande do Sul. Accessed January 23, 2021.
http://hdl.handle.net/10183/149951.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Corrêa, Daniel dos Santos. “Realidade virtual e sensores inerciais no desenvolvimento da tecnologia assistiva : um sistema para estudo da marcha humana baseado em fusão de sensores inerciais.” 2015. Web. 23 Jan 2021.
Vancouver:
Corrêa DdS. Realidade virtual e sensores inerciais no desenvolvimento da tecnologia assistiva : um sistema para estudo da marcha humana baseado em fusão de sensores inerciais. [Internet] [Thesis]. Universidade do Rio Grande do Sul; 2015. [cited 2021 Jan 23].
Available from: http://hdl.handle.net/10183/149951.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Corrêa DdS. Realidade virtual e sensores inerciais no desenvolvimento da tecnologia assistiva : um sistema para estudo da marcha humana baseado em fusão de sensores inerciais. [Thesis]. Universidade do Rio Grande do Sul; 2015. Available from: http://hdl.handle.net/10183/149951
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
13.
Frazão, Paulo José Riccio.
Estudo da correlação da densidade mineral óssea obtida pelo método de absorciometria radiográfica com a resistência óssea do terceiro metacarpiano de eqüinos submetido a ensaios biomecânicos.
Degree: Mestrado, Clínica Cirúrgica Veterinária, 2008, University of São Paulo
URL: http://www.teses.usp.br/teses/disponiveis/10/10137/tde-17112008-152015/
;
► A fundamentação de métodos diagnósticos precoces na ortopedia de eqüinos é de extrema importância clínica, cirúrgica e econômica. O presente estudo teve como objetivo estudar…
(more)
▼ A fundamentação de métodos diagnósticos precoces na ortopedia de eqüinos é de extrema importância clínica, cirúrgica e econômica. O presente estudo teve como objetivo estudar a correlação da densidade mineral óssea do terceiro metacarpiano de eqüinos, obtida pelo método de absorciometria radiográfica, com a resistência dos mesmos quando submetidos a ensaios biomecânicos de compressão e flexão. Utilizaram-se trinta pares de osso terceiro metacarpiano de eqüinos adultos, os quais foram dissecados, radiografados, analisados pelo método de absorciometria radiográfica, submetidos ao estudo tomográfico e a ensaios biomecânicos. Através dos dados obtidos não se observou correlação significativa entre os valores de densidade óptica radiográfica e as propriedades biomecânicas do osso terceiro metacarpiano. Concluiu-se que não se pode inferir que os valores de densidade óssea obtidos pela absorciometria radiográfica do osso terceiro metacarpiano de um eqüino tenha correlação com a capacidade deste osso de absorver cargas de compressão e flexão.
The complete knowledge about non-invasive methods for early disgnostics in equine orthopedy is economicaly important. This experiment has studied the correlation between bone mineral density determined by radiographic absorptiometry and bone resistance of equine third metacarpal bone submitted to both compression and flexion testings. Thirty pairs of third metacarpal bone of adult horses were collected, dissected, radiographed, analysed by the radiographic absorptiometry technique, and submitted to tomographic study and biomechanical testings. The results have shown there is no significant correlation between radiographic bone density values and biomechanical properties of the third metacarpal bone. Therefore, it has been concluded bone mineral density of the third metacarpal bone determined by radiographic absorptiometry do not predict bone capacity to resist compression and flexion loads.
Advisors/Committee Members: Zoppa, André Luis do Valle de.
Subjects/Keywords: Absorciometria; Absorptiometry; Biomechanical testing; Bone density; Densidade óssea; Ensaio biomecânico; Equine; Eqüinos; Terceiro metacarpiano; Third metacarpal bone
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APA (6th Edition):
Frazão, P. J. R. (2008). Estudo da correlação da densidade mineral óssea obtida pelo método de absorciometria radiográfica com a resistência óssea do terceiro metacarpiano de eqüinos submetido a ensaios biomecânicos. (Masters Thesis). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/10/10137/tde-17112008-152015/ ;
Chicago Manual of Style (16th Edition):
Frazão, Paulo José Riccio. “Estudo da correlação da densidade mineral óssea obtida pelo método de absorciometria radiográfica com a resistência óssea do terceiro metacarpiano de eqüinos submetido a ensaios biomecânicos.” 2008. Masters Thesis, University of São Paulo. Accessed January 23, 2021.
http://www.teses.usp.br/teses/disponiveis/10/10137/tde-17112008-152015/ ;.
MLA Handbook (7th Edition):
Frazão, Paulo José Riccio. “Estudo da correlação da densidade mineral óssea obtida pelo método de absorciometria radiográfica com a resistência óssea do terceiro metacarpiano de eqüinos submetido a ensaios biomecânicos.” 2008. Web. 23 Jan 2021.
Vancouver:
Frazão PJR. Estudo da correlação da densidade mineral óssea obtida pelo método de absorciometria radiográfica com a resistência óssea do terceiro metacarpiano de eqüinos submetido a ensaios biomecânicos. [Internet] [Masters thesis]. University of São Paulo; 2008. [cited 2021 Jan 23].
Available from: http://www.teses.usp.br/teses/disponiveis/10/10137/tde-17112008-152015/ ;.
Council of Science Editors:
Frazão PJR. Estudo da correlação da densidade mineral óssea obtida pelo método de absorciometria radiográfica com a resistência óssea do terceiro metacarpiano de eqüinos submetido a ensaios biomecânicos. [Masters Thesis]. University of São Paulo; 2008. Available from: http://www.teses.usp.br/teses/disponiveis/10/10137/tde-17112008-152015/ ;

University of Oulu
14.
Karjalainen, T. (Teemu).
Nitinol shape memory alloy in flexor tendon repair.
Degree: 2012, University of Oulu
URL: http://urn.fi/urn:isbn:9789514299803
► Abstract Early motion is crucial for tendon healing and functional results after flexor tendon repair in the fingers. Motion, however, causes stress in the repair…
(more)
▼ Abstract
Early motion is crucial for tendon healing and functional results after flexor tendon repair in the fingers. Motion, however, causes stress in the repair site, which can result in failure of the repair. A flexor tendon repair is made with fine calibre sutures, which sets exceptional requirements for the suture materials used in flexor tendon repair.
Nitinol (nickel-titanium alloy) is a shape memory alloy, which can exist in two temperature-dependent forms, soft martensite and stiff austenite. It is possible to fabricate a nitinol wire that is soft and pliable, yet has high tensile strength. It also has excellent biocompatibility. Therefore, it is a potential candidate flexor tendon repair suture material.
This study evaluates biomechanical aspects of martensite nitinol wire as a flexor tendon repair suture material. The study hypothesis was that nitinol wire improves the strength of the repairs compared with the repairs made with conventional suture materials. It was found that nitinol core repairs and circumferential repairs performed significantly better when compared with repairs made with commonly used braided polyester and polypropylene of equal calibre.
To further optimise the performance of the nitinol wire in tendon surgery, two experimental models were developed to study the suture-tendon interface. The aim was to prevent pull-out of the suture loop so that surgeons could have full advantage of the tensile strength of the nitinol suture. First, it was tested whether it is possible to improve the suture’s ability to grip the tendon tissue by changing the suture type from monofilament to multifilament. Multifilament suture loops reached higher pull-out strength when compared with round monofilament loops when a locking loop was used. Subsequently, the grip of four different previously reported core repair loops was tested. Based on their failure mechanism, two novel loops were developed. The novel loops demonstrated superior ability to grip the tendon. The novel loops can be useful with high tensile strength suture materials and in repairs, which are prone to suture pull-out.
Tiivistelmä
Varhainen korjauksen jälkeinen aktiivinen kuntoutus on osoittautunut hyödylliseksi jänteen paranemiselle. Varhainen liike altistaa korjauksen kuormitukselle, joka voi johtaa korjauksen pettämiseen. Korjaukset tehdään ohuilla langoilla. Tämä asettaa erityisiä vaatimuksia jännekorjauksessa käytettävälle ommelainemateriaalille.
Nikkeli-titaani (nitinoli) on nk. muistimetalli. Sillä on kaksi lämpötilariippuvaista muotoa: pehmeä martensiitti ja jäykkä austeniitti. Nitinolista voidaan valmistaa ohutta pehmeää ja taipuisaa lankaa, jonka vetolujuus on suuri. Nitinolin siedettävyys jännekudoksessa on todettu hyväksi, minkä vuoksi se on lupaava materiaali käytettäväksi jännekorjauksissa.
Tässä tutkimuksessa kokeiltiin martensiittisen nitinolilangan käyttöä jänteen ydinompeleena ja pintaompeleena. Olettamuksena oli, että nitinolilangalla saadaan kestävämpiä korjauksia kuin nykyään käytössä olevilla langoilla. Tulosten…
Advisors/Committee Members: Ryhänen, J. (Jorma), Jämsä, T. (Timo).
Subjects/Keywords: Nickel-titanium; biomechanical testing; flexor tendon repair; nitinol; suture; biomekaaninen testaus; koukistajajännekorjaus; muistimetalli; nikkeli-titaani; nitinoli; ommelaine
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Karjalainen, T. (. (2012). Nitinol shape memory alloy in flexor tendon repair. (Doctoral Dissertation). University of Oulu. Retrieved from http://urn.fi/urn:isbn:9789514299803
Chicago Manual of Style (16th Edition):
Karjalainen, T (Teemu). “Nitinol shape memory alloy in flexor tendon repair.” 2012. Doctoral Dissertation, University of Oulu. Accessed January 23, 2021.
http://urn.fi/urn:isbn:9789514299803.
MLA Handbook (7th Edition):
Karjalainen, T (Teemu). “Nitinol shape memory alloy in flexor tendon repair.” 2012. Web. 23 Jan 2021.
Vancouver:
Karjalainen T(. Nitinol shape memory alloy in flexor tendon repair. [Internet] [Doctoral dissertation]. University of Oulu; 2012. [cited 2021 Jan 23].
Available from: http://urn.fi/urn:isbn:9789514299803.
Council of Science Editors:
Karjalainen T(. Nitinol shape memory alloy in flexor tendon repair. [Doctoral Dissertation]. University of Oulu; 2012. Available from: http://urn.fi/urn:isbn:9789514299803

University of Western Ontario
15.
Ching, Michael.
Biomechanics Analysis of Anterior Cortical Perforation in Antegrade Femoral Nailing.
Degree: 2019, University of Western Ontario
URL: https://ir.lib.uwo.ca/etd/6795
► Hip and femur fractures are a common problem in an aging population. The number of hip and femur fractures are on the rise in Canada.…
(more)
▼ Hip and femur fractures are a common problem in an aging population. The number of hip and femur fractures are on the rise in Canada. Cephalomedullary fixation is a common method of treating hip and femur fractures, with a known complication of anterior cortical perforation of the distal femur. The literature describes risk factors, such as the influence of the start point at the greater trochanter, but there is no consensus on management. Some cases are treated with restricted weightbearing and other cases with revision surgery. Restricted weightbearing increases perioperative complications including mortality and decreases functional outcomes.
We analyze the effect of an anterior, neutral, and posterior start point on the axial, bending, and torsional stiffness of the femur along with the proximal and distal stresses in axial stiffness. We also compare a femur with an anterior cortical perforation of the distal femur.
The posterior start point has increased sagittal stiffness compared to the neutral and anterior start points. There is no difference in axial, coronal bending, or torsional stiffness, or proximal or distal stresses. Between a femur with a posterior start point with perforation or without perforation, there is no difference in axial, bending, or torsional stiffness or proximal or distal stresses.
A case report is presented of an 89 year old woman with a basicervical fracture who underwent cephalomedullary nail fixation and suffered an anterior cortical perforation of the distal femur. Her weightbearing was not restricted postoperatively and she was ambulating at 6 weeks. She did not fracture at the perforation.
Subjects/Keywords: anterior cortical perforation of the distal femur; cephalomedullary nail; biomechanical testing; start point; femoral bow; hip fracture; Orthopedics
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Ching, M. (2019). Biomechanics Analysis of Anterior Cortical Perforation in Antegrade Femoral Nailing. (Thesis). University of Western Ontario. Retrieved from https://ir.lib.uwo.ca/etd/6795
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Ching, Michael. “Biomechanics Analysis of Anterior Cortical Perforation in Antegrade Femoral Nailing.” 2019. Thesis, University of Western Ontario. Accessed January 23, 2021.
https://ir.lib.uwo.ca/etd/6795.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Ching, Michael. “Biomechanics Analysis of Anterior Cortical Perforation in Antegrade Femoral Nailing.” 2019. Web. 23 Jan 2021.
Vancouver:
Ching M. Biomechanics Analysis of Anterior Cortical Perforation in Antegrade Femoral Nailing. [Internet] [Thesis]. University of Western Ontario; 2019. [cited 2021 Jan 23].
Available from: https://ir.lib.uwo.ca/etd/6795.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Ching M. Biomechanics Analysis of Anterior Cortical Perforation in Antegrade Femoral Nailing. [Thesis]. University of Western Ontario; 2019. Available from: https://ir.lib.uwo.ca/etd/6795
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Boise State University
16.
Nesbitt, Derek.
Effect of Age and Fiber Orientation on Localized Tensile Failure Behavior in Human Meniscus.
Degree: 2018, Boise State University
URL: https://scholarworks.boisestate.edu/td/1487
► The knee meniscus is a soft fibrous tissue that is subjected to large and repetitive loading, and is frequently torn. Tears of the meniscus are…
(more)
▼ The knee meniscus is a soft fibrous tissue that is subjected to large and repetitive loading, and is frequently torn. Tears of the meniscus are painful and cause knee instability, which contributes to the development of osteoarthritis, an irreversible and debilitating condition. Meniscus tears commonly occur from single high-magnitude loads that disrupt the highly aligned fibrous network, with a higher incidence of meniscus tears occurring in older populations.
The objective of this study is to determine the effect of age and fiber alignment on the localized failure behavior of the lateral human knee meniscus during tensile loading. Testing consisted of a single quasi-static pull to failure while imaging with a high-speed camera. Digital image correlation was used to calculate the magnitude of the principal strains local to the failure initiation site, and the angle of the failure plane. Tests were performed on specimens from “young” and “aged” donors under 40 and over 65 years old, respectively, and loaded along or perpendicular to the preferred fiber axis.
Results showed that the local first principal strains at failure were two to three-fold greater than the clamp-to-clamp strains. Age of the donor tissue had no significant impact on any of the stresses, strains, or failure planes measured. Testing perpendicular and along the fibers had failure strains of 129% and 34% respectively, and failure plane angles of 20° and 44°, respectively. These results indicate that failures initiate in the ground substance when loaded along the fiber direction, as the failures occur closest to the plane of maximum shearing of the ground substance at 45°, rather than maximum axial elongation of the fibers.
For the first time, this study has measured the failure plane of the meniscus relative to the reinforcing fibers, and has measured the principal strains of the human lateral meniscus using a full field approach. This is also the first study to investigate the effect of age on the failure properties of the human lateral meniscus. Results from this experimental study can be used to develop and validate mathematical models that describe and predict meniscus failure, and thereby give insight into methods to treat and prevent this prevalent injury.
Subjects/Keywords: meniscus tears; digital image correlation; tensile testing; knee osteoarthritis; soft tissue mechanics; high-speed strain mapping; Biomechanical Engineering; Biomechanics and Biotransport
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Nesbitt, D. (2018). Effect of Age and Fiber Orientation on Localized Tensile Failure Behavior in Human Meniscus. (Thesis). Boise State University. Retrieved from https://scholarworks.boisestate.edu/td/1487
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Nesbitt, Derek. “Effect of Age and Fiber Orientation on Localized Tensile Failure Behavior in Human Meniscus.” 2018. Thesis, Boise State University. Accessed January 23, 2021.
https://scholarworks.boisestate.edu/td/1487.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Nesbitt, Derek. “Effect of Age and Fiber Orientation on Localized Tensile Failure Behavior in Human Meniscus.” 2018. Web. 23 Jan 2021.
Vancouver:
Nesbitt D. Effect of Age and Fiber Orientation on Localized Tensile Failure Behavior in Human Meniscus. [Internet] [Thesis]. Boise State University; 2018. [cited 2021 Jan 23].
Available from: https://scholarworks.boisestate.edu/td/1487.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Nesbitt D. Effect of Age and Fiber Orientation on Localized Tensile Failure Behavior in Human Meniscus. [Thesis]. Boise State University; 2018. Available from: https://scholarworks.boisestate.edu/td/1487
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

The Ohio State University
17.
Ball, Rebecca L.
<i>In Vitro</i> Biomechanical Comparison of
Double Versus Single Plated Tibial Plateau Leveling Osteotomy
Constructs in Axial Loading.
Degree: MS, Veterinary Clinical Sciences, 2009, The Ohio State University
URL: http://rave.ohiolink.edu/etdc/view?acc_num=osu1243976640
► The tibial plateau leveling osteotomy (TPLO) was introduced in 1993 as an innovative surgical procedure to treat stifle instability secondary to rupture of the…
(more)
▼ The tibial plateau leveling osteotomy (TPLO)
was introduced in 1993 as an innovative surgical procedure to treat
stifle instability secondary to rupture of the cranial cruciate
ligament (CCL) (Slocum 1993). The TPLO procedure eliminates cranial
tibial thrust by converting this force into a compressive joint
reaction force without restoring the passive constraint of the
cranial cruciate ligament, resulting in a stable stifle during the
stance phase of the gait cycle (Slocum 1993, Sahar 2006). The
osteotomy created is stabilized by one of a variety of custom
designed TPLO plates all of which vary in design characteristics,
material and
biomechanical properties. Large and
giant breed dogs have been shown to have a predisposition to
develop rupture of the cranial cruciate ligament at a young age and
biomechanical data regarding the performance of TPLO implants in
these breeds is lacking (Duval 1999, Whitehair 1993). The objective
of this study was to compare the axial stiffness of TPLO constructs
stabilized with a single Synthes® broad TPLO plate (TPLO-broad) or
a Slocum TPLO plate and a limited contact dynamic compression plate
(LC-DCP) (TPLO-double). Synthetic bone models
were randomly assigned to one of two groups. All models underwent a
standard TPLO and were stabilized with either a Synthes® Broad TPLO
plate or a Slocum TPLO plate and a LC-DCP. A gap was maintained at
the osteotomy during plate application. Constructs were testes in
axial compression and axial displacement and loads were recorded.
Construct stiffness was calculated from load-displacement curves
and comparisons of mean stiffness were
performed. The mean construct stiffness for the
TPLO-broad constructs was not significantly different from that of
the TPLO-double constructs. The minimum effective number of
implants should be used clinically to achieve stability when
performing a TPLO. Implant stiffness is a key contributor to the
stability of an osteotomy and is integral to osteotomy
healing.
Advisors/Committee Members: Dyce, Jonathan (Advisor).
Subjects/Keywords: Veterinary Services; TPLO; biomechanical testing; axial loading; bone plate
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Ball, R. L. (2009). <i>In Vitro</i> Biomechanical Comparison of
Double Versus Single Plated Tibial Plateau Leveling Osteotomy
Constructs in Axial Loading. (Masters Thesis). The Ohio State University. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=osu1243976640
Chicago Manual of Style (16th Edition):
Ball, Rebecca L. “<i>In Vitro</i> Biomechanical Comparison of
Double Versus Single Plated Tibial Plateau Leveling Osteotomy
Constructs in Axial Loading.” 2009. Masters Thesis, The Ohio State University. Accessed January 23, 2021.
http://rave.ohiolink.edu/etdc/view?acc_num=osu1243976640.
MLA Handbook (7th Edition):
Ball, Rebecca L. “<i>In Vitro</i> Biomechanical Comparison of
Double Versus Single Plated Tibial Plateau Leveling Osteotomy
Constructs in Axial Loading.” 2009. Web. 23 Jan 2021.
Vancouver:
Ball RL. <i>In Vitro</i> Biomechanical Comparison of
Double Versus Single Plated Tibial Plateau Leveling Osteotomy
Constructs in Axial Loading. [Internet] [Masters thesis]. The Ohio State University; 2009. [cited 2021 Jan 23].
Available from: http://rave.ohiolink.edu/etdc/view?acc_num=osu1243976640.
Council of Science Editors:
Ball RL. <i>In Vitro</i> Biomechanical Comparison of
Double Versus Single Plated Tibial Plateau Leveling Osteotomy
Constructs in Axial Loading. [Masters Thesis]. The Ohio State University; 2009. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=osu1243976640

Youngstown State University
18.
Austin, Brittany Logan.
A Biomechanical Investigation of Collagen, Platelet-rich
Plasma, and Mesenchymal Stromal Cells on the Achilles Tendon in a
Rat Model.
Degree: MSin Engineering, Department of Mechanical, Industrial and Manufacturing
Engineering, 2019, Youngstown State University
URL: http://rave.ohiolink.edu/etdc/view?acc_num=ysu155905140840335
► It is estimated that about 18 out of 100,000 people rupture their Achilles tendon every year. A review of 4000 Achilles tendon ruptures found that…
(more)
▼ It is estimated that about 18 out of 100,000 people
rupture their Achilles tendon every year. A review of 4000 Achilles
tendon ruptures found that 75% were related to sports activities.
Currently, the methods for fixing Achilles tendon ruptures are in
need of improvement. Due to the prevalence of Achilles tendon
injuries in sports and the fact that tendons have poor wound
healing, there has been an abundance of studies on treatments for
Achilles tendon injuries. Many different techniques and therapies
using biologics have been researched. One area, however, that has
not been well researched is the addition of a combination of
mesenchymal stromal cells and platelet-rich plasma as a treatment
method for wound healing enhancement. There is also a lack of
studies comparing different treatment methods as they progress
through time. This study chose the following treatment methods:
collagen (CoTa); collagen and platelet-rich plasma (PRP); collagen
and mesenchymal stromal cells (MSC); and collagen, platelet-rich
plasma, and mesenchymal stromal cells (CPM) to follow through two
recovery times: 1 week and 2 weeks. Lewis rats were chosen and a
full transection of the right Achilles tendon was performed 6 mm
proximal to the calcaneal bone. At 1 or 2 weeks both Achilles
tendons of the rats were extracted and tensile tests were
performed. Maximum force, engineering stress, strain, modulus of
elasticity, total strain energy, and elastic strain energy were
determined. Differences in the treatment groups at 1 week recovery
were notable, no differences were found between the treatment
groups at 2 week recovery, however differences could be seen when
compared to the left virgin tissue controls. Computational modeling
led to preliminary finite element models for each treatment group.
Validation for each model was achieved by comparison with
experimental data. Further development of the finite element
analysis would allow for a more accurate model and allow for better
comparisons between treatment groups.
Advisors/Committee Members: Marie, Hazel (Advisor).
Subjects/Keywords: Biomedical Engineering; Biomechanics; Biomedical Research; biomedical; Achilles; tendon; biomechanical testing; mesenchymal stromal cells; platelet-rich plasma; biologics
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Austin, B. L. (2019). A Biomechanical Investigation of Collagen, Platelet-rich
Plasma, and Mesenchymal Stromal Cells on the Achilles Tendon in a
Rat Model. (Masters Thesis). Youngstown State University. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=ysu155905140840335
Chicago Manual of Style (16th Edition):
Austin, Brittany Logan. “A Biomechanical Investigation of Collagen, Platelet-rich
Plasma, and Mesenchymal Stromal Cells on the Achilles Tendon in a
Rat Model.” 2019. Masters Thesis, Youngstown State University. Accessed January 23, 2021.
http://rave.ohiolink.edu/etdc/view?acc_num=ysu155905140840335.
MLA Handbook (7th Edition):
Austin, Brittany Logan. “A Biomechanical Investigation of Collagen, Platelet-rich
Plasma, and Mesenchymal Stromal Cells on the Achilles Tendon in a
Rat Model.” 2019. Web. 23 Jan 2021.
Vancouver:
Austin BL. A Biomechanical Investigation of Collagen, Platelet-rich
Plasma, and Mesenchymal Stromal Cells on the Achilles Tendon in a
Rat Model. [Internet] [Masters thesis]. Youngstown State University; 2019. [cited 2021 Jan 23].
Available from: http://rave.ohiolink.edu/etdc/view?acc_num=ysu155905140840335.
Council of Science Editors:
Austin BL. A Biomechanical Investigation of Collagen, Platelet-rich
Plasma, and Mesenchymal Stromal Cells on the Achilles Tendon in a
Rat Model. [Masters Thesis]. Youngstown State University; 2019. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=ysu155905140840335

University of Rochester
19.
Loiselle, Alayna Erin.
The Role of Bone Marrow Derived Matrix
Metalloproteinase-9 During Flexor Tendon Healing.
Degree: PhD, 2009, University of Rochester
URL: http://hdl.handle.net/1802/8055
► Flexor tendon healing involves a coordinated response of many cells and tissues, with unique temporal and spatial patterns of gene expression. Primary flexor tendon repairs…
(more)
▼ Flexor tendon healing involves a coordinated
response of many cells and tissues, with unique temporal and
spatial patterns of gene expression. Primary flexor tendon repairs
are associated with significant clinical complications, the most
notable being formation of fibrous adhesions that decrease the
range of motion of the affected digit.
Using a murine model of
flexor tendon healing, we have shown that there is a biphasic
response of the gelatinolytic matrix metalloproteinases (Mmps)
after injury and repair. Mmp-9 (Gelatinase B) is highly expressed
on day seven post-repair during the early inflammatory phase and is
associated with the degradation of damaged collagen at the injury
site. Collagen catabolism sends out chemotactic signals to recruit
ECM secreting fibroblasts to the repair site. Th abundant matrix
deposition acts to restore tendon integrity, but also results in
adhesion formation that limits the gliding function of the tendon.
In contrast, Mmp-2 (Gelatinase A) expression is highest at day 21,
and breakdown of collagen at this time results in remodeling of the
tendon, and a decrease in adhesions.
Loss of Mmp-9 during the
tendon healing process using Mmp-9-/- mice resulted in earlier
remodeling of adhesions, without any decline in the maximum load at
failure of the repaired tendons compared to wild type mice,
indicating that this is an important target for therapeutic
intervention.
To determine the molecular mechanism of Mmp-9
induction, primary tenocytes were isolated and treated with
Prostaglandin E2 (PGE2), which is a modulator of the inflammatory
response and is increased after tendon injury.
Tenocytes
responded to PGE2 by increasing expression and activity of Mmp-2,
however Mmp-9 expression was not altered. Using GFP bone marrow
chimeric mice, we have shown that there is an influx of bone marrow
derived cells to the repair site after flexor tendon injury, so the
response of cultured bone marrow cells to PGE2 was determined.
Mmp-9 expression and activity were significantly increased in
response to PGE2 in bone marrow cells, and this induction was
mediated through the EP4 prostanoid receptor.
To definitively
determine that bone marrow cells migrate to the repair site and
produce Mmp-9, leading to adhesion formation, Mmp-9-/- (KO) bone
marrow was transplanted in to wild type (WT) mice, while WT bone
marrow was transplanted in to KO mice. Healing tendons from WT mice
with KO bone marrow had a significant decrease in adhesion
formation compared to KO mice with WT bone marrow. Additionally,
there was no Mmp-9 detected by In situ hybridization in WT animals
with KO bone marrow, and there was abundant Mmp-9 detected in
Mmp-9-/- mice with WT bone marrow. This highlights a potentially
important role for inhibition of Bone Marrow derived Mmp-9 during
flexor tendon healing.
Targeting bone marrow derived Mmp-9 during
the flexor tendon healing process represents a possible therapeutic
intervention to decrease adhesion formation, while not compromising
any strength of the repair, which could have…
Subjects/Keywords: MMP-9; Flexor Tendon; Tendon Healing; Bone Marrow; Adhesions; Biomechanical Testing
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APA (6th Edition):
Loiselle, A. E. (2009). The Role of Bone Marrow Derived Matrix
Metalloproteinase-9 During Flexor Tendon Healing. (Doctoral Dissertation). University of Rochester. Retrieved from http://hdl.handle.net/1802/8055
Chicago Manual of Style (16th Edition):
Loiselle, Alayna Erin. “The Role of Bone Marrow Derived Matrix
Metalloproteinase-9 During Flexor Tendon Healing.” 2009. Doctoral Dissertation, University of Rochester. Accessed January 23, 2021.
http://hdl.handle.net/1802/8055.
MLA Handbook (7th Edition):
Loiselle, Alayna Erin. “The Role of Bone Marrow Derived Matrix
Metalloproteinase-9 During Flexor Tendon Healing.” 2009. Web. 23 Jan 2021.
Vancouver:
Loiselle AE. The Role of Bone Marrow Derived Matrix
Metalloproteinase-9 During Flexor Tendon Healing. [Internet] [Doctoral dissertation]. University of Rochester; 2009. [cited 2021 Jan 23].
Available from: http://hdl.handle.net/1802/8055.
Council of Science Editors:
Loiselle AE. The Role of Bone Marrow Derived Matrix
Metalloproteinase-9 During Flexor Tendon Healing. [Doctoral Dissertation]. University of Rochester; 2009. Available from: http://hdl.handle.net/1802/8055

Vanderbilt University
20.
Weis, Jared Anthony.
A finite element inverse analysis to assess functional improvement during the fracture healing process.
Degree: MS, Biomedical Engineering, 2009, Vanderbilt University
URL: http://hdl.handle.net/1803/14378
► Assessment of the restoration of load-bearing function is the central goal in the study of fracture healing process. During the fracture healing, two critical aspects…
(more)
▼ Assessment of the restoration of load-bearing function is the central goal in the study of fracture healing process. During the fracture healing, two critical aspects affect its analysis: (1) material properties of the callus components, and (2) the spatio-temporal architecture of the callus with respect to cartilage and new bone formation. In this study, an inverse problem methodology is used which takes into account both features and yields material property estimates that can analyze the healing changes. Six stabilized fractured mouse tibias are obtained at two time points during the most active phase of the healing process, respectively 10 days (n=3), and 14 days (n=3) after fracture. Under the same displacement conditions, the inverse procedure estimations of the callus material properties are generated and compared to other fracture healing metrics. The FEA estimated property is the only metric shown to be statistically significant (p=0.0194) in detecting the changes in the stiffness that occur during the healing time points. In addition, simulation studies regarding sensitivity to initial guess and noise are presented, as well as the influence of callus architecture on the FEA estimated material property metric. The finite element model inverse analysis developed can be used to determine the effects of genetics or therapeutic manipulations on fracture healing in rodents.
Advisors/Committee Members: Robert J. Roselli (committee member), Michael I. Miga (committee member).
Subjects/Keywords: Fracture healing; Biomechanical testing; Finite element analysis; Material properties; Micro-CT
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Weis, J. A. (2009). A finite element inverse analysis to assess functional improvement during the fracture healing process. (Thesis). Vanderbilt University. Retrieved from http://hdl.handle.net/1803/14378
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Weis, Jared Anthony. “A finite element inverse analysis to assess functional improvement during the fracture healing process.” 2009. Thesis, Vanderbilt University. Accessed January 23, 2021.
http://hdl.handle.net/1803/14378.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Weis, Jared Anthony. “A finite element inverse analysis to assess functional improvement during the fracture healing process.” 2009. Web. 23 Jan 2021.
Vancouver:
Weis JA. A finite element inverse analysis to assess functional improvement during the fracture healing process. [Internet] [Thesis]. Vanderbilt University; 2009. [cited 2021 Jan 23].
Available from: http://hdl.handle.net/1803/14378.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Weis JA. A finite element inverse analysis to assess functional improvement during the fracture healing process. [Thesis]. Vanderbilt University; 2009. Available from: http://hdl.handle.net/1803/14378
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universidade do Estado do Rio de Janeiro
21.
Silvio Sandro Cornélio.
Efeito da associação de dieta hiperlipídica e hipoestrogenismo sobre a integridade óssea mandibular de ratas
.
Degree: Master, 2010, Universidade do Estado do Rio de Janeiro
URL: http://www.bdtd.uerj.br/tde_busca/arquivo.php?codArquivo=1502
;
► O aumento da expectativa de vida permite a mulher viver muitos anos após a menopausa. Além disso, a mudança nos hábitos alimentares da sociedade moderna…
(more)
▼ O aumento da expectativa de vida permite a mulher viver muitos anos após a menopausa. Além disso, a mudança nos hábitos alimentares da sociedade moderna tem determinado o aumento da incidência de obesidade e sobrepeso na população. Essas duas situações têm despertado o interesse da comunidade científica, visto as repercussões deletérias que podem ocorrer com o organismo. O objetivo deste estudo foi avaliar o efeito da deficiência de estrogênio associado à dieta hiperlipídica sobre a integridade óssea da mandíbula de ratas. Para tal, ratas Wistar jovens foram avaliadas por citologia vaginal e aos 90 dias de idade, divididas em 4 grupos: Controle (C4%), Controle hiperlipídica19% (C19%), Ovariectomizada 4% (OVX4%) e Ovariectomizada19% (OVX19%). O período experimental começou com a castração (90 d de idade), seguido da alimentação com dieta hiperlipídica, por 30 dias. Ao final desse período, após anestesia, o sangue foi coletado para análise sérica de cálcio, fósforo, fosfatase alcalina e estradiol. Mandíbulas, vértebras L4 e fêmures foram removidos e preparados para análise das propriedades físicas e biomecânicas. Não foram observadas diferenças na ingestão alimentar, no comprimento corporal nem nas medidas ósseas dos grupos. O cálcio sérico diminuiu significativamente nos grupos castrados. O fósforo diminuiu enquanto, a fosfatase alcalina aumentou em todos os grupos, quando comparados ao C4%. Dentre os parâmetros físicos avaliados alguns apresentaram diferenças entre os grupos. Nas vértebras L4, os pesos imersos e úmidos aumentaram com a castração e com a dieta hiperlipídica, enquanto, os percentuais de material orgânico e mineral diminuíram. Nas mandíbulas, os pesos imersos e úmidos e a densidade óssea aumentaram com a castração, mas diminuem com a associação castração/dieta hiperlipídica. O volume ósseo e o percentual de água diminuíram com a ingestão de dieta hiperlipídica. Nenhuma alteração foi observada nos fêmures. Nas cinzas das mandíbulas os percentuais de magnésio apresentaram-se significativamente aumentados em todos os grupos. Mas, os de cálcio e fósforo não variaram. Nos testes biomecânicos de vértebra L4 e fêmur não foram encontradas
diferenças entre os grupos. No entanto, na mandíbula os grupos alimentados com dieta hiperlipídica apresentaram menor resistência à tensão aplicada, em relação aos grupos de dieta normolipídica. Ficou evidenciado nessas ratas que a deficiência de esteróides sexuais associada à dieta hiperlipídica influencia de forma negativa a integridade óssea mandibular.
Increased life expectancy of women allows her to live many years after menopause. On the other hand, the western way of life has brought about an increased incidence of obesity and overweight to people. These two situations have attracted the interest of the scientific community, given the deleterious consequences that may occur with the body. The aim of this study was to evaluate the effect of estrogen deficiency associated with high-fat diet on the mandibular bone integrity of rats. Wistar young rats were…
Advisors/Committee Members: Fabio Ramoa Pires, Rachel Aisengart Menezes, Marisa Maria Dreyer Breitenbach, Celly Cristina Alves do Nascimento Saba.
Subjects/Keywords: Biomechanical testing; Physic parameters; Ovariectomy; Fat diet; Mandible; Ratas; Ensaio biomecânico; ANALISE NUTRICIONAL DE POPULACAO; Mandíbula; Ovariectomia; Ratos; Ovariectomia; Parâmetros físicos; Dieta hiperlipídica; Mandíbula; Rats
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Cornélio, S. S. (2010). Efeito da associação de dieta hiperlipídica e hipoestrogenismo sobre a integridade óssea mandibular de ratas
. (Masters Thesis). Universidade do Estado do Rio de Janeiro. Retrieved from http://www.bdtd.uerj.br/tde_busca/arquivo.php?codArquivo=1502 ;
Chicago Manual of Style (16th Edition):
Cornélio, Silvio Sandro. “Efeito da associação de dieta hiperlipídica e hipoestrogenismo sobre a integridade óssea mandibular de ratas
.” 2010. Masters Thesis, Universidade do Estado do Rio de Janeiro. Accessed January 23, 2021.
http://www.bdtd.uerj.br/tde_busca/arquivo.php?codArquivo=1502 ;.
MLA Handbook (7th Edition):
Cornélio, Silvio Sandro. “Efeito da associação de dieta hiperlipídica e hipoestrogenismo sobre a integridade óssea mandibular de ratas
.” 2010. Web. 23 Jan 2021.
Vancouver:
Cornélio SS. Efeito da associação de dieta hiperlipídica e hipoestrogenismo sobre a integridade óssea mandibular de ratas
. [Internet] [Masters thesis]. Universidade do Estado do Rio de Janeiro; 2010. [cited 2021 Jan 23].
Available from: http://www.bdtd.uerj.br/tde_busca/arquivo.php?codArquivo=1502 ;.
Council of Science Editors:
Cornélio SS. Efeito da associação de dieta hiperlipídica e hipoestrogenismo sobre a integridade óssea mandibular de ratas
. [Masters Thesis]. Universidade do Estado do Rio de Janeiro; 2010. Available from: http://www.bdtd.uerj.br/tde_busca/arquivo.php?codArquivo=1502 ;

McMaster University
22.
Muizelaar, Aaron.
Prototype Development for the Treatment of Periprosthetic Fractures of the Distal Femur.
Degree: MASc, 2012, McMaster University
URL: http://hdl.handle.net/11375/12510
► Current stabilization methods for periprosthetic fractures of the distal femur have been inadequate in achieving sufficient fixation and can lead to complications rates as…
(more)
▼ Current stabilization methods for periprosthetic fractures of the distal femur have been inadequate in achieving sufficient fixation and can lead to complications rates as high as 29%. Therefore, the overall objective of this study was to design, manufacture and evaluate (experimentally and computationally) a novel plating method for improving the treatment of periprosthetic fractures of the distal femur. Medial and lateral prototype plates were designed and manufactured based on the geometry of a synthetic femur and a femoral prosthesis. The two plates were linked via a compression screw and a small tab on each plate that inserts into pre-existing slots on the prosthesis to enhance rigidity of the construct. Synthetic femurs were used to assess the ability of the prototype plates to stabilize a periprosthetic fracture compared to a traditional single lateral plate. Each femur was subjected to a testing protocol that involved compressive and bending loading of the sample. The relative motion between the distal and proximal fragments during loading was then measured using both 2D and 3D motion tracking techniques. Both techniques revealed that the prototype bilateral plates were able to reduce motion of the fracture site compared to a single lateral plate. The final objective concerned the development of a finite element model to represent the experimental testing. The fracture gap motion obtained from the final model did not completely agree with the experimental data; however, additional experimental measurements found that the majority of these differences could be attributed to simplification made at the tab-slot interaction. Despite the difference, the model represents a significant step forward in the simulation of periprosthetic fracture treatment, and further refinement would allow for optimization of the plate design. Overall, the results of this thesis indicate that an alternative approach to treating periprosthetic fractures exists that is capable of improving fracture stabilization.
Master of Applied Science (MASc)
Advisors/Committee Members: Wohl, Gregory, Quenneville, Cheryl, Winemaker, Mitchell, Mechanical Engineering.
Subjects/Keywords: periprosthetic fracture; distal femur; bilateral fracture fixation plates; biomechanics; biomechanical testing; finite element analysis; Biomedical devices and instrumentation; Biomedical devices and instrumentation
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Muizelaar, A. (2012). Prototype Development for the Treatment of Periprosthetic Fractures of the Distal Femur. (Masters Thesis). McMaster University. Retrieved from http://hdl.handle.net/11375/12510
Chicago Manual of Style (16th Edition):
Muizelaar, Aaron. “Prototype Development for the Treatment of Periprosthetic Fractures of the Distal Femur.” 2012. Masters Thesis, McMaster University. Accessed January 23, 2021.
http://hdl.handle.net/11375/12510.
MLA Handbook (7th Edition):
Muizelaar, Aaron. “Prototype Development for the Treatment of Periprosthetic Fractures of the Distal Femur.” 2012. Web. 23 Jan 2021.
Vancouver:
Muizelaar A. Prototype Development for the Treatment of Periprosthetic Fractures of the Distal Femur. [Internet] [Masters thesis]. McMaster University; 2012. [cited 2021 Jan 23].
Available from: http://hdl.handle.net/11375/12510.
Council of Science Editors:
Muizelaar A. Prototype Development for the Treatment of Periprosthetic Fractures of the Distal Femur. [Masters Thesis]. McMaster University; 2012. Available from: http://hdl.handle.net/11375/12510

University of Akron
23.
Parikh, Anand.
LONG-TERM CRANIAL RECONSTRUCTIONS IN FULL THICKNESS DEFECTS
USING CARBONATED CALCIUM PHOSPHATE CEMENT WITH TITANIUM MESH
SCAFFOLD IN A SHEEP MODEL: BIOMECHANICAL ANALYSIS.
Degree: MSin Engineering, Biomedical Engineering, 2006, University of Akron
URL: http://rave.ohiolink.edu/etdc/view?acc_num=akron1164993505
► Autogenous bone graft (ABG) is considered the evaluation standard for cranial defect reconstruction material. A variety of bone substitutes have been used as alternative materials…
(more)
▼ Autogenous bone graft (ABG) is considered the
evaluation standard for cranial defect reconstruction material. A
variety of bone substitutes have been used as alternative materials
for this procedure, each having its own advantages and
disadvantages. Carbonated calcium phosphate (CCPP), a biomaterial
form of hydroxyapatite (HA), has been increasingly used for cranial
reconstructions. For defects of certain size and shape, CCPP is
used with a titanium mesh for structural stability. At the present
time there have been no published studies in the literature
comparing the
biomechanical and histological properties of these
cranial bone reconstruction structures over time. In this study two
different reconstruction structures were compared to autogenous
bone grafts with respect to time. Reconstruction structure A (RCA)
used a slow setting CCPP, whereas reconstruction structure B (RCB)
used a fast setting CCPP. Unilateral or bilateral cranial defect
reconstructions were conducted on sheep with full thickness defect
sizes of 1.5 × 3.0 cm. A total of 24 sheep were divided into eight
groups with post surgical periods of 0, 6 and 12 months. The
skulls’
biomechanical properties were evaluated using a free weight
drop test protocol. In addition, intact parietal bone was also
evaluated at 12 months as a control. Peak acceleration, peak force
transmission and time to peak acceleration parameters obtained from
the drop weight test were used for analysis. Immediately
post-surgery there were no significant differences in any
biomechanical characteristics of the experimental groups. At 12
months, the autogenous bone graft (ABG) reconstructions had a
significantly superior impact characteristic compared to
reconstructions of slow setting CCPP with titanium mesh scaffold
and reconstructions of fast setting CCPP with titanium mesh
scaffold (p<0.05). At 12 months ABG was not significantly
different from the intact bone (p>0.05).
Advisors/Committee Members: Njus, Glen (Advisor).
Subjects/Keywords: Biomechanical testing; Drop weight test; Hydroxyapatite cement; Cranial reconstruction; Calcium phosphate cement
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Parikh, A. (2006). LONG-TERM CRANIAL RECONSTRUCTIONS IN FULL THICKNESS DEFECTS
USING CARBONATED CALCIUM PHOSPHATE CEMENT WITH TITANIUM MESH
SCAFFOLD IN A SHEEP MODEL: BIOMECHANICAL ANALYSIS. (Masters Thesis). University of Akron. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=akron1164993505
Chicago Manual of Style (16th Edition):
Parikh, Anand. “LONG-TERM CRANIAL RECONSTRUCTIONS IN FULL THICKNESS DEFECTS
USING CARBONATED CALCIUM PHOSPHATE CEMENT WITH TITANIUM MESH
SCAFFOLD IN A SHEEP MODEL: BIOMECHANICAL ANALYSIS.” 2006. Masters Thesis, University of Akron. Accessed January 23, 2021.
http://rave.ohiolink.edu/etdc/view?acc_num=akron1164993505.
MLA Handbook (7th Edition):
Parikh, Anand. “LONG-TERM CRANIAL RECONSTRUCTIONS IN FULL THICKNESS DEFECTS
USING CARBONATED CALCIUM PHOSPHATE CEMENT WITH TITANIUM MESH
SCAFFOLD IN A SHEEP MODEL: BIOMECHANICAL ANALYSIS.” 2006. Web. 23 Jan 2021.
Vancouver:
Parikh A. LONG-TERM CRANIAL RECONSTRUCTIONS IN FULL THICKNESS DEFECTS
USING CARBONATED CALCIUM PHOSPHATE CEMENT WITH TITANIUM MESH
SCAFFOLD IN A SHEEP MODEL: BIOMECHANICAL ANALYSIS. [Internet] [Masters thesis]. University of Akron; 2006. [cited 2021 Jan 23].
Available from: http://rave.ohiolink.edu/etdc/view?acc_num=akron1164993505.
Council of Science Editors:
Parikh A. LONG-TERM CRANIAL RECONSTRUCTIONS IN FULL THICKNESS DEFECTS
USING CARBONATED CALCIUM PHOSPHATE CEMENT WITH TITANIUM MESH
SCAFFOLD IN A SHEEP MODEL: BIOMECHANICAL ANALYSIS. [Masters Thesis]. University of Akron; 2006. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=akron1164993505

University of Kentucky
24.
Hunt, Stephanie L.
Collagen Crosslinking Reagent Utilized to Modify the Mechanical Properties of the Soft Palate in Equine Snoring and Apnea Applications.
Degree: 2015, University of Kentucky
URL: https://uknowledge.uky.edu/cbme_etds/36
► Snoring is a sleep disruption that can lead to obstructive sleep apnea (OSA), which interrupts breathing by obstructing the airway. Injecting a protein crosslinker, such…
(more)
▼ Snoring is a sleep disruption that can lead to obstructive sleep apnea (OSA), which interrupts breathing by obstructing the airway. Injecting a protein crosslinker, such as genipin, into the soft palate could decrease the severity of snoring and OSA by stiffening the soft palate. Equine soft palates modeled human palates due to a high incidence of awake snoring and apnea.
The pilot in vivo study treated six horses with two 100 mM injections of the buffered genipin reagent. The efficacy phase horses underwent respiratory audio recordings to document snoring changes using Matlab and ImageJ in the time and frequency domains. Histological analysis was completed on the safety phase palates post treatment.
All horses were successfully treated with the genipin injections. At least one horse showed high frequency amplitude reductions, and all horses had low frequency amplitude reductions, correlating to a reduction in palatal displacement and snoring loudness. One efficacy horse appears to have been completely cured. The histological analysis presented tissue damage, mucosal tissue damage, and mild inflammation due to palate expansion and errant injections.
Different injection volumes and techniques should be investigated next. Applying this treatment to human studies for snoring and OSA applications is the ultimate goal.
Subjects/Keywords: Obstructive sleep apnea; snoring; soft palate stiffening; sound analysis of snoring; biomechanical testing of soft tissue; Biomechanics and Biotransport; Biomedical Devices and Instrumentation; Other Biomedical Engineering and Bioengineering
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Hunt, S. L. (2015). Collagen Crosslinking Reagent Utilized to Modify the Mechanical Properties of the Soft Palate in Equine Snoring and Apnea Applications. (Masters Thesis). University of Kentucky. Retrieved from https://uknowledge.uky.edu/cbme_etds/36
Chicago Manual of Style (16th Edition):
Hunt, Stephanie L. “Collagen Crosslinking Reagent Utilized to Modify the Mechanical Properties of the Soft Palate in Equine Snoring and Apnea Applications.” 2015. Masters Thesis, University of Kentucky. Accessed January 23, 2021.
https://uknowledge.uky.edu/cbme_etds/36.
MLA Handbook (7th Edition):
Hunt, Stephanie L. “Collagen Crosslinking Reagent Utilized to Modify the Mechanical Properties of the Soft Palate in Equine Snoring and Apnea Applications.” 2015. Web. 23 Jan 2021.
Vancouver:
Hunt SL. Collagen Crosslinking Reagent Utilized to Modify the Mechanical Properties of the Soft Palate in Equine Snoring and Apnea Applications. [Internet] [Masters thesis]. University of Kentucky; 2015. [cited 2021 Jan 23].
Available from: https://uknowledge.uky.edu/cbme_etds/36.
Council of Science Editors:
Hunt SL. Collagen Crosslinking Reagent Utilized to Modify the Mechanical Properties of the Soft Palate in Equine Snoring and Apnea Applications. [Masters Thesis]. University of Kentucky; 2015. Available from: https://uknowledge.uky.edu/cbme_etds/36
25.
Salb, Kelly N.
Development and Application of a BioRobotic Simulation of Stance Phase Gait to Study Foot and Ankle Kinematics.
Degree: MS, Biomedical Engineering, 2013, University of Tennessee Health Science Center
URL: https://dc.uthsc.edu/dissertations/223
► Ankle instantaneous axis of rotation (IAR) measurements represent a more complete parameter for characterizing joint motion. However, few studies have implemented this measurement to…
(more)
▼ Ankle instantaneous axis of rotation (IAR) measurements represent a more complete parameter for characterizing joint motion. However, few studies have implemented this measurement to study normal, injured, or pathological foot-ankle biomechanics. Additionally, while load is suggested to play a major role in ankle biomechanics, including influences on articular surfaces, bony motion, and formation of the arches, studies concerning the effects of joint loading are limited.
A novel
testing protocol was developed to simulate in vivo mechanics of the foot-ankle complex during early stance phase gait in a human cadaveric model. Two studies were conducted. The first study was to assess the repeatability and accuracy of an existing robotic
testing platform (RTP) and loading protocol using force measurements and IAR data from two cadaver specimens. A lower leg was mounted in a RTP with the tibia upright and foot flat on the baseplate. Axial tibia loads (ATLs) were controlled as a function of a vertical ground reaction force (vGRF) set at half body weight (356N) and a 50% vGRF (178N) Achilles tendon (AT) load. Two specimens were repetitively loaded over 10 degrees dorsiflexion and 20 degrees plantarflexion. Platform axes were controlled within 2µm and 0.008 degrees resulting in ATL measurements within ±2N of target conditions. Mean ATLs and IAR values were not significantly different between cycles of motion, but IAR values were between dorsiflexion and plantarflexion. A linear regression analysis showed no significant differences between slopes of plantarflexion paths.
The second study aimed to determine the effects of a passive (unloaded) and active Achilles and axial tibial loads on ankle mechanics using IAR data and translational and rotational data of the calcaneus, talus, and navicular from four cadaver specimens during stance phase gait. Specimens were mounted in the RTP with the tibia upright and foot flat on the baseplate. Passive loading applied a 5N ATL with no AT. Active ATLs were controlled as a function of a vGRF set at body weight (534N) and static ATs set at 25%, 50%, 75%, 100% vGRF. Four specimens were repetitively loaded over 10 degrees dorsiflexion and 10 degrees plantarflexion. An optoelectric motion measuring system was used to track bony talus, calcaneus, and navicular translations and rotations. Kinematics in passive motion were predominantly governed by the shape of the mating articular surfaces. Once actively loaded, net joint loading had no surgically relevant effect on the kinematics data other than to suggest they were governed more by soft tissue structures.
The customized robotic platform and advanced
testing protocol produced repeatable and accurate measurements of the IAR.
Biomechanical properties of the foot and ankle were demonstrated, including the tibiotalar and soft tissue relationship on the axis of rotation and the effect of load on foot-ankle kinematics. The platform and protocol can be useful for assessing foot-ankle biomechanics under different loading scenarios…
Advisors/Committee Members: Denis J. DiAngelo, Ph.D..
Subjects/Keywords: Biomechanical Testing; Foot and Ankle; Gait Simulation; Kinematics; Robotics; Analytical, Diagnostic and Therapeutic Techniques and Equipment; Equipment and Supplies; Investigative Techniques; Medicine and Health Sciences
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Salb, K. N. (2013). Development and Application of a BioRobotic Simulation of Stance Phase Gait to Study Foot and Ankle Kinematics. (Thesis). University of Tennessee Health Science Center. Retrieved from https://dc.uthsc.edu/dissertations/223
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Salb, Kelly N. “Development and Application of a BioRobotic Simulation of Stance Phase Gait to Study Foot and Ankle Kinematics.” 2013. Thesis, University of Tennessee Health Science Center. Accessed January 23, 2021.
https://dc.uthsc.edu/dissertations/223.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Salb, Kelly N. “Development and Application of a BioRobotic Simulation of Stance Phase Gait to Study Foot and Ankle Kinematics.” 2013. Web. 23 Jan 2021.
Vancouver:
Salb KN. Development and Application of a BioRobotic Simulation of Stance Phase Gait to Study Foot and Ankle Kinematics. [Internet] [Thesis]. University of Tennessee Health Science Center; 2013. [cited 2021 Jan 23].
Available from: https://dc.uthsc.edu/dissertations/223.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Salb KN. Development and Application of a BioRobotic Simulation of Stance Phase Gait to Study Foot and Ankle Kinematics. [Thesis]. University of Tennessee Health Science Center; 2013. Available from: https://dc.uthsc.edu/dissertations/223
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
26.
Hillyard, Daniel Clay.
A Novel Distractive and Mobility-Enabling Lumbar Spinal Orthosis for Treating Mechanical Low Back Pain.
Degree: PhD, Biomedical Engineering, 2017, University of Tennessee Health Science Center
URL: https://dc.uthsc.edu/dissertations/428
► Introduction: Lumbar spinal orthoses (LSOs) are often used as non-surgical treatment and serve to support the spine and alleviate low back pain. More recently, dynamic…
(more)
▼ Introduction: Lumbar spinal orthoses (LSOs) are often used as non-surgical treatment and serve to support the spine and alleviate low back pain. More recently, dynamic orthoses claiming to decompress the spine have been introduced. Currently, there is an unserved population of people that suffer from mechanical low back pain (LBP) conditions, such as degenerative disc disease or lumbar foraminal stenosis, that would benefit from spinal decompression and mobility. A previously-developed prototype of dynamic mobility orthosis (DMO1) was designed that provided a distractive load across the lumbar spine but required higher sagittal bending moments and was unable to maintain spinal off-loading throughout extended ranges of movement. The research objectives were to a) Design a new orthosis that reduced bending moment build up and sustained spinal off-loading throughout daily living ranges of flexion and extension movement, b) Test the new orthosis prototype in a controlled laboratory environment, and c) Organize and carry out a clinical pilot study with patients suffering from mechanical LBP to determine the immediate and short-term effects of the new orthosis prototype on LBP and overall patient quality of life.
Methods: A mechanical analog upper torso model and programmable robotic
testing platform were used to design features of the new prototype (DMO2): a mobility-enabling component (MEC) and a distractive force component (DFC). The DMO2 prototype was tested in a robotic
testing platform (RTP) under a 300 N applied vertical torso load over a range of 25° flexion to 10° of extension utilizing a previously-developed protocol. For DMO2, loads carried by the brace were determined throughout flexion and extension. Applied moments to upper torso model and transferred moments to spine were measured. The difference in applied and transferred moments represented brace moment effects.
It was determined that DMO2 had limitations, primarily with providing a distractive force to actual human subjects. Because of this, a new orthosis prototype (DMO3) was developed that improved upon the design of the DMO2 MEC and DFC. The DMO3 prototype was designed to provide a constant distractive force with minimal resistance to bending while effectively providing a distractive force to the wearer that could be felt. Also, the MEC of DMO3 included both flexion and extension as well as axial rotation. The DMO3 prototype was tested in the RTP under a 150 N applied vertical load over a range of 25° flexion to 10° of extension utilizing a previously-developed protocol. Also, the DMO3 prototype was tested in the RTP under simulated axial rotation without an applied vertical torso load. For this test, a measurement was made that determined how much axial rotation DMO3 allowed.
A clinical study was organized in which two patients with LBP wore the DMO3 prototype during six physical therapy (PT) treatment sessions. Before the treatment sessions began, the patient had a radiograph (x-ray 1) taken and the patient completed a Modified Oswestry Disability…
Advisors/Committee Members: Denis J. DiAngelo, Ph.D..
Subjects/Keywords: Biomechanical testing; Low back pain; Lumbar spinal orthosis; Analytical, Diagnostic and Therapeutic Techniques and Equipment; Medicine and Health Sciences; Other Analytical, Diagnostic and Therapeutic Techniques and Equipment; Therapeutics
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
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APA (6th Edition):
Hillyard, D. C. (2017). A Novel Distractive and Mobility-Enabling Lumbar Spinal Orthosis for Treating Mechanical Low Back Pain. (Doctoral Dissertation). University of Tennessee Health Science Center. Retrieved from https://dc.uthsc.edu/dissertations/428
Chicago Manual of Style (16th Edition):
Hillyard, Daniel Clay. “A Novel Distractive and Mobility-Enabling Lumbar Spinal Orthosis for Treating Mechanical Low Back Pain.” 2017. Doctoral Dissertation, University of Tennessee Health Science Center. Accessed January 23, 2021.
https://dc.uthsc.edu/dissertations/428.
MLA Handbook (7th Edition):
Hillyard, Daniel Clay. “A Novel Distractive and Mobility-Enabling Lumbar Spinal Orthosis for Treating Mechanical Low Back Pain.” 2017. Web. 23 Jan 2021.
Vancouver:
Hillyard DC. A Novel Distractive and Mobility-Enabling Lumbar Spinal Orthosis for Treating Mechanical Low Back Pain. [Internet] [Doctoral dissertation]. University of Tennessee Health Science Center; 2017. [cited 2021 Jan 23].
Available from: https://dc.uthsc.edu/dissertations/428.
Council of Science Editors:
Hillyard DC. A Novel Distractive and Mobility-Enabling Lumbar Spinal Orthosis for Treating Mechanical Low Back Pain. [Doctoral Dissertation]. University of Tennessee Health Science Center; 2017. Available from: https://dc.uthsc.edu/dissertations/428
27.
Λαμπράκης, Ανδρέας.
Βελτιστοποίηση συρραφής ρήξεων μηνίσκου με τη χρήση υλικών με μνήμη σχήματος: πειραματική μελέτη.
Degree: 2008, National and Kapodistrian University of Athens; Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών (ΕΚΠΑ)
URL: http://hdl.handle.net/10442/hedi/23494
► Purpose: To evaluate the biomechanical results of meniscal repair in vitro by a Nitinol suture and compare them to Ethibond and Nylon. Methods: The six…
(more)
▼ Purpose: To evaluate the biomechanical results of meniscal repair in vitro by a Nitinol suture and compare them to Ethibond and Nylon. Methods: The six testing groups consisted of Nitinol, Ethibond and Nylon sutures (2-0 and 3-0). Forty-nine bovine menisci with a vertical longitudinal tear were repaired with one horizontal mattress suture and were fully immersed into a water bath, adjusted to a tensile testing machine. SMA were subjected to 7% elongation in a cold bath prior suturing, which was regained (suture contraction) after immersion of the repaired meniscus in the higher temperature bath of the testing machine. All specimens were subjected to tensile testing and Force/Displacement curves were obtained. Load to 5 mm gap, load to failure, tensile strength, stiffness and mode of failure for each suture group were recorded. Statistical analysis included analysis of variance with Bonferroni correction for the post hoc multiple comparisons. Results: Nylon sutures achieved the lowest scores in all measurements. SMA achieved better, but not significant, scores than Ethibond in load to 5 mm gap and stiffness. The 2-0 and 3-0 SMA suture repair demonstrated the highest average tensile strength and load to failure, with significant differences, being 31% and 50% stronger than Ethibond. Mode of failure included pulling-through the inner segment of meniscus and rupture of the suture at the knot. Conclusions: Nitinol is a promising meniscal suture material, providing better strength properties than conventional sutures and equivalent repair stiffness to Ethibond.
Σκοπός: Τα εμβιομηχανικά αποτελέσματα μηνισκικής συρραφής από ράμμα Nitinol εκτιμήθηκαν in vitro και συγκρίθηκαν με ράμματα Ethibond και Nylon. Μέθοδος: Ράμματα (2.0 και 3.0) από Nitinol, Ethibond και Nylon συγκροτούσαν τις έξι υπό μελέτη ομάδες. Σαραντα-εννέα βόειοι μηνίσκοι με εγκάρσια ρήξη υποβλήθηκαν σε συρραφή με μία οριζόντια ραφή δίκην mattress. Εν συνεχεία εμβαπτίστηκαν πλήρως σε θερμολουτρό, κατάλληλα προσαρμοσμένο σε μηχανή εφελκυσμού. Όλα τα δοκίμια υποβλήθηκαν σε εφελκυσμό και ελήφθησαν Καμπύλες Δύναμης/Μετατόπισης. Οι τιμές φορτίων σε 5 χιλ. διάσταση, φορτίων αστοχίας, τάσης εφελκυσμού, δυσκαμψίας και ο μηχανισμός αστοχίας για κάθε κατηγορία ράμματος καταγράφησαν. Η στατιστική επεξεργασία περιελάμβανε ανάλυση διασποράς (ANOVA) με διόρθωση τύπου Bonferroni για τις πολλαπλές συγκρίσεις. Αποτελέσματα: Τα ράμματα Nylon παρουσίασαν τις χαμηλότερες τιμές σε όλες τις μετρήσεις. Στατιστικά σημαντικές διαφορές δεν παρατηρήθηκαν μεταξύ των SMA και Ethibond στα φορτία πρόκλησης 5 χιλ. διάστασης και στη δυσκαμψία των ραμμάτων. Η ραφή με 2.0 και 3.0 SMA παρουσίασε την υψηλότερη μέση τάση εφελκυσμού και φορτίου αστοχίας, όντας 31% και 50% αντίστοιχα ισχυρότερη της ραφής με Εthibond. Ο μηχανισμός αστοχίας περιελάμβανε την απόσχιση μηνισκικού ιστού από το ράμμα και τη ρήξη του ράμματος στον κόμπο. Συμπεράσματα: Το κράμα Nitinol κρίνεται υποσχόμενο υλικό μηνισκικής συρραφής, παρέχοντας ισχυρότερες μηχανικές ιδιότητες και παρόμοιες τιμές δυσκαμψίας σε σχέση με το…
Subjects/Keywords: Μηνίσκος; Συρραφή; Εμβιομηχανική μελέτη; Μέταλλα με μνήμη σχήματος; Επιδιόρθωση; Meniscus; Suturing; Biomechanical testing; Shape memory alloys; Repair
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Λαμπράκης, . . (2008). Βελτιστοποίηση συρραφής ρήξεων μηνίσκου με τη χρήση υλικών με μνήμη σχήματος: πειραματική μελέτη. (Thesis). National and Kapodistrian University of Athens; Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών (ΕΚΠΑ). Retrieved from http://hdl.handle.net/10442/hedi/23494
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Λαμπράκης, Ανδρέας. “Βελτιστοποίηση συρραφής ρήξεων μηνίσκου με τη χρήση υλικών με μνήμη σχήματος: πειραματική μελέτη.” 2008. Thesis, National and Kapodistrian University of Athens; Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών (ΕΚΠΑ). Accessed January 23, 2021.
http://hdl.handle.net/10442/hedi/23494.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Λαμπράκης, Ανδρέας. “Βελτιστοποίηση συρραφής ρήξεων μηνίσκου με τη χρήση υλικών με μνήμη σχήματος: πειραματική μελέτη.” 2008. Web. 23 Jan 2021.
Vancouver:
Λαμπράκης . Βελτιστοποίηση συρραφής ρήξεων μηνίσκου με τη χρήση υλικών με μνήμη σχήματος: πειραματική μελέτη. [Internet] [Thesis]. National and Kapodistrian University of Athens; Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών (ΕΚΠΑ); 2008. [cited 2021 Jan 23].
Available from: http://hdl.handle.net/10442/hedi/23494.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Λαμπράκης . Βελτιστοποίηση συρραφής ρήξεων μηνίσκου με τη χρήση υλικών με μνήμη σχήματος: πειραματική μελέτη. [Thesis]. National and Kapodistrian University of Athens; Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών (ΕΚΠΑ); 2008. Available from: http://hdl.handle.net/10442/hedi/23494
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
28.
Goh, Frederick.
Wearable Hip Protectors: Validation of a Novel Test System and Evaluation Utilizing Pressure Sensing Methods.
Degree: 2017, University of Waterloo
URL: http://hdl.handle.net/10012/12135
► Hip fractures are strongly associated with sideway falls to the hip, poor response time, lack of soft tissue energy absorption, and subpar proximal femur strength…
(more)
▼ Hip fractures are strongly associated with sideway falls to the hip, poor response time, lack of soft tissue energy absorption, and subpar proximal femur strength (Cummings and Nevitt, 2001). Hip protectors are a common intervention aimed to lower the femoral neck loads below the fracture threshold and reduce the risk of hip fracture (Robinovitch et al., 2009). These protective devices typically consist of a padded material embedded in undergarments which absorb or shunt impact energies. Lack of testing standards for these protective devices have resulted in many unregulated hip protectors produced, a wide range of biomechanical test results represented by various test systems, and inconclusive clinical trials (Combes and Price, 2014; Kannus et al., 1999; Laing et al., 2011; van Schoor et al., 2006). The International Hip Protector Research Group (IHPRG) have consolidated evidence-based recommendations for the specifications and parameters for a biomechanical hip protector test system (Robinovitch et al., 2009).
A drop tower and surrogate pelvis test system was developed to evaluate various hip protectors in a simulated sideways fall from a range of impact velocities. This test system was validated using the IHPRG recommendations and compared with femoral neck loads for unpadded and padded conditions in Laing et al. (2011). After testing combinations from 3 different foam products and 2 different trochanteric soft tissue thicknesses (TSTT), the selected baseline hip form consisted of a FlexFoam-iT! V product at a 24 mm TSTT. When tested at a 3.4 m/s impact velocity, this baseline hip form had an average peak femoral neck force of 2145 N and an average peak neck force attenuation of 20.1% and 25.9% for Hipsaver and Safehip Air-X protectors respectively, which closely matched the test system used in Laing et al. (2011). The test system with this baseline hip form was then verified to have excellent reliability between trials (ICC = 0.99 average across impact velocities) and poor reliability between hip forms (ICC range = -0.18 to 0.404 between impact velocities). Additionally, the hip form did not incur any visible interior or exterior damage after being drop tested for 60 repeated impacts at the specified various velocities.
Only a few studies had previously looked into pressure distribution of hip protectors during simulated falls. Limitations in literature include the evaluation of pressure only at the outer surface of the hip protector and at low impact velocities. The Tekscan I-Scan pressure mapping system allowed for measurements directly at the hip protector-skin interface for impact velocities up to 3.4 m/s. The goal of this study was to look at significant differences between hip protector conditions for various force and pressure-related outcome variables, investigate which pressure-related variables were related to the traditional biomechanical effectiveness metric, and to provide initial insight regarding the protective mechanism of hip protector designs. Significant differences between the unpadded…
Subjects/Keywords: Hip Fracture; Hip Protector; Older Adult; Pressure Sensor; Surrogate Pelvis; Impact Testing; Biomechanical Standards
…Schematic of drop tower used for biomechanical testing of hip protectors… …16
Table 1-5: Summary of biomechanical testing results of six commonly used hip protectors… …inhibited by lack
of biomechanical testing standards, unclear clinical trial results, and under… …recommendations for biomechanical testing (Robinovitch et al., 2009).
Table 1-1: Review of… …undergarments.
Biomechanical testing studies had shown that hip protectors can attenuate femoral neck…
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Goh, F. (2017). Wearable Hip Protectors: Validation of a Novel Test System and Evaluation Utilizing Pressure Sensing Methods. (Thesis). University of Waterloo. Retrieved from http://hdl.handle.net/10012/12135
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Goh, Frederick. “Wearable Hip Protectors: Validation of a Novel Test System and Evaluation Utilizing Pressure Sensing Methods.” 2017. Thesis, University of Waterloo. Accessed January 23, 2021.
http://hdl.handle.net/10012/12135.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Goh, Frederick. “Wearable Hip Protectors: Validation of a Novel Test System and Evaluation Utilizing Pressure Sensing Methods.” 2017. Web. 23 Jan 2021.
Vancouver:
Goh F. Wearable Hip Protectors: Validation of a Novel Test System and Evaluation Utilizing Pressure Sensing Methods. [Internet] [Thesis]. University of Waterloo; 2017. [cited 2021 Jan 23].
Available from: http://hdl.handle.net/10012/12135.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Goh F. Wearable Hip Protectors: Validation of a Novel Test System and Evaluation Utilizing Pressure Sensing Methods. [Thesis]. University of Waterloo; 2017. Available from: http://hdl.handle.net/10012/12135
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

New Jersey Institute of Technology
29.
Uko, Linda.
Biomechanical testing of upright range of motion versus overhead supine range of motion.
Degree: MSin Biomedical Engineering - (M.S.), Biomedical Engineering, 2008, New Jersey Institute of Technology
URL: https://digitalcommons.njit.edu/theses/374
► Rehabilitation of an elbow, following injury, is not a well-studied subject. Clinically, there is not a general consensus on which recovery method is optimal…
(more)
▼ Rehabilitation of an elbow, following injury, is not a well-studied
subject. Clinically, there is not a general consensus on which recovery method is optimal for healing an unstable elbow. When dealing with medial collateral ligament deficiency, many authors have proposed several forearm positions that will yield proper healing of the unstable elbow. Some researchers believe that active mobilization of the elbow with the arm in a vertical position is a safe protocol for rehabilitation with the forearm oriented in a supine pronated position. It was also mentioned that the compressive forces due to the active mobilization of the arm will stabilize the MCL deficient elbow'. This study is unique in that the proposal is that supine overhead range of motion will stabilize the MCL deficient elbow because gravity will act as a compressive force keeping the MCL deficient elbow intact. In this study, the gravitational stabilizing factor will be demonstrated comparing both the supine overhead range of motion and the commonly used upright range of motion protocol. The hypothesis is that supine overhead range of motion provides stability to a collateral deficient elbow. Moreover, supine overhead range of motion is a superior way to rehabilitate an unstable elbow because the forces of gravity hold the elbow in concentric reduction rather than distracting the elbow joint when the forearm is rehabilitated in an upright manner. The overhead ROM provided more stability to the unstable elbow, more especially to the elbows with the AC still intact.
Advisors/Committee Members: Virak Tan, Richard A. Foulds, Sergei Adamovich.
Subjects/Keywords: MCL deficient elbow; Biomechanical testing; Supine overhead range of motion; Upright range of motion; Biomedical Engineering and Bioengineering
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Uko, L. (2008). Biomechanical testing of upright range of motion versus overhead supine range of motion. (Thesis). New Jersey Institute of Technology. Retrieved from https://digitalcommons.njit.edu/theses/374
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Uko, Linda. “Biomechanical testing of upright range of motion versus overhead supine range of motion.” 2008. Thesis, New Jersey Institute of Technology. Accessed January 23, 2021.
https://digitalcommons.njit.edu/theses/374.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Uko, Linda. “Biomechanical testing of upright range of motion versus overhead supine range of motion.” 2008. Web. 23 Jan 2021.
Vancouver:
Uko L. Biomechanical testing of upright range of motion versus overhead supine range of motion. [Internet] [Thesis]. New Jersey Institute of Technology; 2008. [cited 2021 Jan 23].
Available from: https://digitalcommons.njit.edu/theses/374.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Uko L. Biomechanical testing of upright range of motion versus overhead supine range of motion. [Thesis]. New Jersey Institute of Technology; 2008. Available from: https://digitalcommons.njit.edu/theses/374
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Gothenburg / Göteborgs Universitet
30.
Macdonald, Warren 1954-.
On component integration in total hip arthroplasty. Pre-clinical evaluation.
Degree: 2000, University of Gothenburg / Göteborgs Universitet
URL: http://hdl.handle.net/2077/12900
Subjects/Keywords: Total hip arthroplasty; orthopaedic implants; implant design; biomechanical testing; in vitro evaluation; titanium; zirconia; polyethylene; surgical accuracy
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Record Details
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Macdonald, W. 1. (2000). On component integration in total hip arthroplasty. Pre-clinical evaluation. (Thesis). University of Gothenburg / Göteborgs Universitet. Retrieved from http://hdl.handle.net/2077/12900
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Macdonald, Warren 1954-. “On component integration in total hip arthroplasty. Pre-clinical evaluation.” 2000. Thesis, University of Gothenburg / Göteborgs Universitet. Accessed January 23, 2021.
http://hdl.handle.net/2077/12900.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Macdonald, Warren 1954-. “On component integration in total hip arthroplasty. Pre-clinical evaluation.” 2000. Web. 23 Jan 2021.
Vancouver:
Macdonald W1. On component integration in total hip arthroplasty. Pre-clinical evaluation. [Internet] [Thesis]. University of Gothenburg / Göteborgs Universitet; 2000. [cited 2021 Jan 23].
Available from: http://hdl.handle.net/2077/12900.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Macdonald W1. On component integration in total hip arthroplasty. Pre-clinical evaluation. [Thesis]. University of Gothenburg / Göteborgs Universitet; 2000. Available from: http://hdl.handle.net/2077/12900
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
◁ [1] [2] ▶
.