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University of Florida

1. Singh, Srishti. Targeted Drug Design for Carbonic Anhydrase IX.

Degree: MS, Biochemistry and Molecular Biology, 2018, University of Florida

Human Carbonic Anhydrase IX (CA IX) is a zinc metalloenzyme that catalyzes the conversion of carbon dioxide to bicarbonate and proton and is involved in tumorigenesis. CA IX helps in maintaining intracellular pH (pHi) to near physiological pH and at the same time contribute in the acidification of extracellular pH (pHe) in solid tumors, thereby leading to tumor progression and survival. Studies have shown that targeting CA IX can inhibit tumor growth and metastasis. Advisors/Committee Members: MCKENNA,ROBERT (committee chair), FROST,SUSAN COOKE (committee member).

Subjects/Keywords: benzenesulfonamides  – crystallography  – hypoxia

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Singh, S. (2018). Targeted Drug Design for Carbonic Anhydrase IX. (Masters Thesis). University of Florida. Retrieved from https://ufdc.ufl.edu/UFE0054076

Chicago Manual of Style (16th Edition):

Singh, Srishti. “Targeted Drug Design for Carbonic Anhydrase IX.” 2018. Masters Thesis, University of Florida. Accessed November 27, 2020. https://ufdc.ufl.edu/UFE0054076.

MLA Handbook (7th Edition):

Singh, Srishti. “Targeted Drug Design for Carbonic Anhydrase IX.” 2018. Web. 27 Nov 2020.

Vancouver:

Singh S. Targeted Drug Design for Carbonic Anhydrase IX. [Internet] [Masters thesis]. University of Florida; 2018. [cited 2020 Nov 27]. Available from: https://ufdc.ufl.edu/UFE0054076.

Council of Science Editors:

Singh S. Targeted Drug Design for Carbonic Anhydrase IX. [Masters Thesis]. University of Florida; 2018. Available from: https://ufdc.ufl.edu/UFE0054076

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