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1. Mansouri Boroujeni, Misagh. Dynamic Simulation and Neuromuscular Control of Movement: Applications for Predictive Simulations of Balance Recovery.

Degree: 2015, University of Tennessee – Knoxville

Balance is among the most challenging tasks for patients with movement disorders. Study and treatment of these disorders could greatly benefit from combined software tools that offer better insights into neuromuscular biomechanics, and predictive capabilities for optimal surgical and rehabilitation treatment planning. A platform was created to combine musculoskeletal modeling, closed-loop forward dynamic simulation, optimization techniques, and neuromuscular control system design. Spinal (stretch-reflex) and supraspinal (operational space task-based) controllers were developed to test simulation-based hypotheses related to balance recovery and movement control. A corrective procedure (rectus femoris transfer surgery) was targeted for children experiencing stiff-knee gait and how this procedure may affect their balance recovery. Clinical movement analysis and simulation-based approaches were combined to understand the biomechanical consequences of this surgical procedure. The closed-loop controller was extended by merging approaches from robotics and biomechanics. A prioritized multi-task, support-consistent, task-based controller was implemented inside the simulation platform to synthesize human balance. The simulated results were validated with experimental data of healthy adults by defining surrogate response surfaces that represent the patients’ primary tasks (e.g., to keep their balance) as function of defined subtasks (e.g. swing leg positions or torso orientations). The potential of using this platform to study, predict functional outcomes and perhaps improve treatments for musculoskeletal conditions is exciting and valuable. This project not only integrates software tools, but also allows integration of neuroscientists, physiologists, biomechanists, and physical therapists to adopt, adapt, and generate new solutions for musculoskeletal conditions.

Subjects/Keywords: Dynamic Simulation of human movement; Neuromuscular control; Rectus Femoris Transfer surgery in children with cerebral palsy; balance recovery simulations; predictive simulation of movement; synthesizing human balance; Biomechanical Engineering; Controls and Control Theory; Dynamics and Dynamical Systems; Movement and Mind-Body Therapies; Rehabilitation and Therapy; Robotics; Surgical Procedures, Operative

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APA (6th Edition):

Mansouri Boroujeni, M. (2015). Dynamic Simulation and Neuromuscular Control of Movement: Applications for Predictive Simulations of Balance Recovery. (Doctoral Dissertation). University of Tennessee – Knoxville. Retrieved from https://trace.tennessee.edu/utk_graddiss/3349

Chicago Manual of Style (16th Edition):

Mansouri Boroujeni, Misagh. “Dynamic Simulation and Neuromuscular Control of Movement: Applications for Predictive Simulations of Balance Recovery.” 2015. Doctoral Dissertation, University of Tennessee – Knoxville. Accessed January 21, 2019. https://trace.tennessee.edu/utk_graddiss/3349.

MLA Handbook (7th Edition):

Mansouri Boroujeni, Misagh. “Dynamic Simulation and Neuromuscular Control of Movement: Applications for Predictive Simulations of Balance Recovery.” 2015. Web. 21 Jan 2019.

Vancouver:

Mansouri Boroujeni M. Dynamic Simulation and Neuromuscular Control of Movement: Applications for Predictive Simulations of Balance Recovery. [Internet] [Doctoral dissertation]. University of Tennessee – Knoxville; 2015. [cited 2019 Jan 21]. Available from: https://trace.tennessee.edu/utk_graddiss/3349.

Council of Science Editors:

Mansouri Boroujeni M. Dynamic Simulation and Neuromuscular Control of Movement: Applications for Predictive Simulations of Balance Recovery. [Doctoral Dissertation]. University of Tennessee – Knoxville; 2015. Available from: https://trace.tennessee.edu/utk_graddiss/3349

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