Advanced search options

Advanced Search Options 🞨

Browse by author name (“Author name starts with…”).

Find ETDs with:

in
/  
in
/  
in
/  
in

Written in Published in Earliest date Latest date

Sorted by

Results per page:

Sorted by: relevance · author · university · dateNew search

You searched for subject:(autoimmune bullous diseases). Showing records 1 – 2 of 2 total matches.

Search Limiters

Last 2 Years | English Only

No search limiters apply to these results.

▼ Search Limiters


University of Oulu

1. Försti, A.-K. (Anna-Kaisa). Incidence, mortality, comorbidities, and treatment of bullous pemphigoid in Finland.

Degree: 2017, University of Oulu

Abstract Bullous pemphigoid (BP) is an autoimmune skin disease predominantly found in elderly people, which causes blistering of the skin and severe itching. The incidence of BP reported by previous studies has varied greatly between 0.05 and 42.8 per 1 million persons per year. Higher incidences have been reported in Western Europe and the USA, while countries around the Mediterranean have reported lower rates. However, the epidemiology of BP has not previously been studied in any Scandinavian country. The one-year mortality of BP is highly variable with estimates between 11% and 41% worldwide. As for comorbidities, the previous studies have shown that BP is associated with neurological disorders. The aim of this study was to investigate the incidence and mortality of BP in Finland, to assess the treatments used for BP, and the potential contribution of systemic glucocorticoid treatment to the high mortality rate found in BP patients. A further aim was to obtain more specific information about the neurological diseases associated with BP, and to clarify the less studied association with psychiatric disorders. For these purposes, we collected the records of all immunologically confirmed BP patients diagnosed in the Oulu University Hospital between 1985 and 2012, and, for a sub-study III, data for all patients diagnosed with BP in Finnish hospitals between 1987 and 2013. We found that the incidence of BP in Northern Finland has increased over the past two decades to approximately 27 new BP cases per 1 million persons per year. The one-year mortality of BP patients is 17%, and the standardized mortality ratio (SMR) is 7.6. Common comorbidities found in the sample of BP patients were: cardiovascular diseases (76%), neurodegenerative diseases (41%), skin conditions other than BP (37%) and type 2 diabetes (23%). Many neurodegenerative diseases of the central nervous system were associated with BP, as were many psychiatric disorders. The association was strongest between multiple sclerosis (MS) and BP, with MS patients having almost a 6-fold higher risk of BP than controls. The present study reports for the first time the incidence and mortality of BP in Finland, and provides new information about the association between BP and neurological and psychiatric disorders.

Tiivistelmä Rakkulainen pemfigoidi (josta jatkossa käytetään nimitystä pemfigoidi) on autoimmuunisairaus, joka esiintyy yleensä iäkkäillä, ja aiheuttaa ihon rakkulointia ja hankalaa kutinaa. Aiemmissa tutkimuksissa pemfigoidin ilmaantuvuus on vaihdellut 0,05:sta 42,8:aan tapaukseen miljoonaa ihmistä kohden vuodessa. Ilmaantuvuuden on havaittu olevan korkeampi Länsi-Euroopassa, kun taas Välimeren ympäristössä ilmaantuvuus on matalampi. Pemfigoidia sairastavien kuolleisuus vuoden kuluessa diagnoosista vaihtelee noin 11-41%:n välillä. Aiemmat tutkimukset ovat myös osoittaneet, että pemfigoidi liittyy neurologisiin sairauksiin. Pemfigoidin epidemiologiaa ei ole kuitenkaan tutkittu Suomessa tai muissa Pohjoismaissa. Tämän tutkimuksen tarkoituksena oli…

Advisors/Committee Members: Tasanen-Määttä, K. (Kaisa), Timonen, M. (Markku).

Subjects/Keywords: Finland; autoimmune bullous diseases; bullous pemphigoid; collagen XVII; epidemiology; incidence; mortality; neurological comorbidity; psychiatric comorbidity; skin diseases; standardized mortality ratio; Suomi; autoimmuunirakkulatauti; epidemiologia; ihosairaus; ilmaantuvuus; kollageeni XVII; kuolleisuus; neurologinen oheissairaus; pemfigoidi; psykiatrinen oheissairaus; rakkulainen pemfigoidi; vakioitu kuolleisuussuhde; BP180

Record DetailsSimilar RecordsGoogle PlusoneFacebookTwitterCiteULikeMendeleyreddit

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Försti, A. -. (. (2017). Incidence, mortality, comorbidities, and treatment of bullous pemphigoid in Finland. (Doctoral Dissertation). University of Oulu. Retrieved from http://urn.fi/urn:isbn:9789526215310

Chicago Manual of Style (16th Edition):

Försti, A -K (Anna-Kaisa). “Incidence, mortality, comorbidities, and treatment of bullous pemphigoid in Finland.” 2017. Doctoral Dissertation, University of Oulu. Accessed November 17, 2019. http://urn.fi/urn:isbn:9789526215310.

MLA Handbook (7th Edition):

Försti, A -K (Anna-Kaisa). “Incidence, mortality, comorbidities, and treatment of bullous pemphigoid in Finland.” 2017. Web. 17 Nov 2019.

Vancouver:

Försti A-(. Incidence, mortality, comorbidities, and treatment of bullous pemphigoid in Finland. [Internet] [Doctoral dissertation]. University of Oulu; 2017. [cited 2019 Nov 17]. Available from: http://urn.fi/urn:isbn:9789526215310.

Council of Science Editors:

Försti A-(. Incidence, mortality, comorbidities, and treatment of bullous pemphigoid in Finland. [Doctoral Dissertation]. University of Oulu; 2017. Available from: http://urn.fi/urn:isbn:9789526215310

2. Λαγογιάννη, Ειρήνη. Διερεύνηση και εκτίμηση συγκεντρώσεων ορισμένων λιπιδιακών παραγόντων σε αυτοάνοσα νοσήματα με δερματολογικές εκδηλώσεις.

Degree: 2002, National and Kapodistrian University of Athens; Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών (ΕΚΠΑ)

Autoimmune diseases affect approximately 5% of the population in Western countries. They are a fascinating but poorly understood group of diseases. The aim of the present study is to provide additional support to the hypothesis that the determination of serum levels of cholesterol, triglycerides, HDL, HDL2, HDL3, CHOLESTEROL/HDL and HDL2/HDL3 could be useful to elucidate possible mechanism for a better assessment of the risk factors of cardiovascular diseases which are involved in autoimmune diseases with manifestations by the skin. 126 subjects were studied (44 men and 82 women), they were shared in 4 groups (34 healthy, 30 patients of EL, 22 patients of scleroderma, 20 patients of autoimmune diseases (pemphigus, bullus pemphigoid, psoriasis, alopecia areata) and 20 patients of skin diseases (dermatitis, eczema). The most important results of this study are the following: 1. Serum levels of cholesterol are increased in patients with, cutaneous erythematosus lupus (discoid EL and subcutaneous EL) compared to healthy group. 2. Serum levels of cholesterol are increased, in patients with autoimmune diseases with manifestations by the skin compared to healthy group. 3. Serum levels of cholesterol are increased in patients with cutaneous erythematosus lupus (discoid EL and subcutaneous EL) compared to skin diseases group. 4. Serum levels of cholesterol are increased in patients with autoimmune diseases with manifestations by the skin compared to skin diseases group. 5. HDL, HDL2, HDL3 levels are significantly lower in patients with cutaneous erythematosus lupus compared to healthy group. 6. HDL, HDL2 levels are significantly lower in patients with morphea compared to healthy group. 7. HDL2 levels are decreased in patients with autoimmune diseases with manifestations by the skin compared to healthy group. 8. HDL2 levels are decreased in patients with skin diseases compared to healthy group. 9. A significant increase in Cholesterol/HDL index is found in patients with LE compared to healthy group. 10. A significant decrease in HDL2/HDL3 ratio is found in with LE compared to healthy group. 11 .A significant decrease in HDL2/HDL3 ratio is found in patients with morphea compared to healthy group. 12. A significant increase in Cholesterol/ HDL index and a significant decrease in HDL2/HDL3 ratio are found in patients with autoimmune diseases with manifestations by the skin compared to healthy group. 13. A significant decrease in HDL2/HDL3 ratio is found in patients with skin diseases compared to healthy group. 14. A significant, increase in Cholesterol/HDL index is found in patients with EL compared to healthy group.15. Serum levels of triglycerides are increased in patients with cutaneous erythematosus lupus (discoid EL and subcutaneous EL) compared to healthy group. 16. Serum levels of triglycerides are increased in patients with autoimmune diseases with manifestations by the skin compare^ to healthy group. 17. Serum levels of triglycerides are increased in patients with cutaneous erythematosus lupus (discoid EL and…

Subjects/Keywords: Λιπίδια; Λιποπρωτεΐνες; Αυτοάνοσα νοσήματα; Χοληστερόλη; Τριγλυκερίδια; Ερυθηματώδης λύκος, δερματικός; Κατά πλάκες σκληροδερμία; Δυσλιπιδαιμίες; Δερματικά νοσήματα; Πέμφιγα; Πεμφιγοειδές; Lipids; Lipoproteins; Autoimmune diseases; Cholesterol; Triglycerides; HDL2; HDL3; HDL ( High Density Lipoprotein ); HDL-Cholesterol; Lupus erythematosus; Morphea; Dyslipidemias; Skin diseases; Pemphigus; Bullous pemphigoid

Record DetailsSimilar RecordsGoogle PlusoneFacebookTwitterCiteULikeMendeleyreddit

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Λαγογιάννη, . . (2002). Διερεύνηση και εκτίμηση συγκεντρώσεων ορισμένων λιπιδιακών παραγόντων σε αυτοάνοσα νοσήματα με δερματολογικές εκδηλώσεις. (Thesis). National and Kapodistrian University of Athens; Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών (ΕΚΠΑ). Retrieved from http://hdl.handle.net/10442/hedi/20289

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Λαγογιάννη, Ειρήνη. “Διερεύνηση και εκτίμηση συγκεντρώσεων ορισμένων λιπιδιακών παραγόντων σε αυτοάνοσα νοσήματα με δερματολογικές εκδηλώσεις.” 2002. Thesis, National and Kapodistrian University of Athens; Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών (ΕΚΠΑ). Accessed November 17, 2019. http://hdl.handle.net/10442/hedi/20289.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Λαγογιάννη, Ειρήνη. “Διερεύνηση και εκτίμηση συγκεντρώσεων ορισμένων λιπιδιακών παραγόντων σε αυτοάνοσα νοσήματα με δερματολογικές εκδηλώσεις.” 2002. Web. 17 Nov 2019.

Vancouver:

Λαγογιάννη . Διερεύνηση και εκτίμηση συγκεντρώσεων ορισμένων λιπιδιακών παραγόντων σε αυτοάνοσα νοσήματα με δερματολογικές εκδηλώσεις. [Internet] [Thesis]. National and Kapodistrian University of Athens; Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών (ΕΚΠΑ); 2002. [cited 2019 Nov 17]. Available from: http://hdl.handle.net/10442/hedi/20289.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Λαγογιάννη . Διερεύνηση και εκτίμηση συγκεντρώσεων ορισμένων λιπιδιακών παραγόντων σε αυτοάνοσα νοσήματα με δερματολογικές εκδηλώσεις. [Thesis]. National and Kapodistrian University of Athens; Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών (ΕΚΠΑ); 2002. Available from: http://hdl.handle.net/10442/hedi/20289

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

.