subject:(Ultrasound imaging)

University of Waterloo

1. Xu, Robert Sheng. An Information Tracking Approach to the Segmentation of Prostates in Ultrasound Imaging.

Degree: 2010, University of Waterloo

► Outlining of the prostate boundary in ultrasound images is a very useful procedure performed and subsequently used by clinicians. The contribution of the resulting segmentation… (more)

Subjects/Keywords: segmentation; ultrasound imaging

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APA (6^th Edition):

Xu, R. S. (2010). An Information Tracking Approach to the Segmentation of Prostates in Ultrasound Imaging. (Thesis). University of Waterloo. Retrieved from http://hdl.handle.net/10012/5208

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Xu, Robert Sheng. “An Information Tracking Approach to the Segmentation of Prostates in Ultrasound Imaging.” 2010. Thesis, University of Waterloo. Accessed October 19, 2019. http://hdl.handle.net/10012/5208.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Xu, Robert Sheng. “An Information Tracking Approach to the Segmentation of Prostates in Ultrasound Imaging.” 2010. Web. 19 Oct 2019.

Vancouver:

Xu RS. An Information Tracking Approach to the Segmentation of Prostates in Ultrasound Imaging. [Internet] [Thesis]. University of Waterloo; 2010. [cited 2019 Oct 19]. Available from: http://hdl.handle.net/10012/5208.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Xu RS. An Information Tracking Approach to the Segmentation of Prostates in Ultrasound Imaging. [Thesis]. University of Waterloo; 2010. Available from: http://hdl.handle.net/10012/5208

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

AUT University

2. Oldfield, Christie Erin. Ultrasound imaging of the distal radioulnar joint: a new method to assess ulna radial translation in forearm rotation .

Degree: 2013, AUT University

URL: http://hdl.handle.net/10292/5164

► The current study was conducted to establish normal values of Distal radioulnar joint (DRUJ) translation using ultrasound imaging (USI). Repeatability of quantifying DRUJ translation of… (more)

▼ The current study was conducted to establish normal values of Distal radioulnar joint (DRUJ) translation using ultrasound imaging (USI). Repeatability of quantifying DRUJ translation of the forearm in various positions using USI was additionally investigated. Lastly the data collected was compared to previously documented values established in the literature using Computerised Tomography (CT) imaging. It is fundamental to further clinical research in this area to ascertain the validity of using USI to quantify DRUJ translation in a normal population. A cross-sectional reliability study was conducted with 23 normal participants. Ultrasound examination was conducted bilaterally on two separate occasions, using the Phillips iU22 diagnostic ultrasound machine. Static transverse images of maximal supination, neutral and maximal pronation, were taken three times. This process was repeated with the participant gripping a 1kg weight for the supination and pronation positions. Using the Sketchbook Express software programme, lines were drawn to assess the relative distance of known bony landmarks. This method is consistent with the rheumatoid arthritis subluxation ratio (RASR) described by Henmi et al. (2007). Statistical analyses of repeatability included a hierarchical mixed model method, analysis of variance (ANOVA) and Cronbach’s alpha. Validity was also assessed comparing data to previously documented values in CT literature. Translation was found to occur in both non gripping supination and pronation compared with neutral (p<0.001). There was statistically significantly more translation found with pronation (mean=1.69mm). Ulna radial translation in supination was found to occur to a lesser extent and in a volar direction compared with neutral (mean=0.67mm). Gripping pronation did not produce statistically significant changes compared to non gripping pronation. However, gripping supination was significantly higher (p<0.01) in comparison to non gripping supination. Cronbach’s alpha measurement for internal consistency was very high (0.9). Other than forearm position, there was no statistically significant difference between hand, left versus right, state or session. The RASR values in the current study demonstrated consistent measurements when compared to previously documented values. This study demonstrated that USI can reliably detect translatory movement of the DRUJ in healthy participants. It supports the role of USI in future musculoskeletal applications and research. Alternative methods to accurately record translation may provide a less expensive and more accessible diagnostic tool in assessing DRUJ instability. This would reduce the dependence on CT or magnetic resonance imaging (MRI) scans to diagnose DRUJ instability in patients after trauma, inflammatory joint diseases or developmental disorders. Advisors/Committee Members: Hing, Wayne (advisor).

Subjects/Keywords: DRUJ; Ultrasound imaging

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APA (6^th Edition):

Oldfield, C. E. (2013). Ultrasound imaging of the distal radioulnar joint: a new method to assess ulna radial translation in forearm rotation . (Thesis). AUT University. Retrieved from http://hdl.handle.net/10292/5164

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Oldfield, Christie Erin. “Ultrasound imaging of the distal radioulnar joint: a new method to assess ulna radial translation in forearm rotation .” 2013. Thesis, AUT University. Accessed October 19, 2019. http://hdl.handle.net/10292/5164.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Oldfield, Christie Erin. “Ultrasound imaging of the distal radioulnar joint: a new method to assess ulna radial translation in forearm rotation .” 2013. Web. 19 Oct 2019.

Vancouver:

Oldfield CE. Ultrasound imaging of the distal radioulnar joint: a new method to assess ulna radial translation in forearm rotation . [Internet] [Thesis]. AUT University; 2013. [cited 2019 Oct 19]. Available from: http://hdl.handle.net/10292/5164.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Oldfield CE. Ultrasound imaging of the distal radioulnar joint: a new method to assess ulna radial translation in forearm rotation . [Thesis]. AUT University; 2013. Available from: http://hdl.handle.net/10292/5164

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Penn State University

3. Kim, In Soo. FULLY INTEGRATED CMOS ULTRASOUND TRANSCEIVER CHIP FOR HIGH-FREQUENCY HIGH-RESOLUTION ULTRASONIC IMAGING SYSTEMS.

Degree: PhD, Electrical Engineering, 2009, Penn State University

URL: https://etda.libraries.psu.edu/catalog/9995

► Ultrasound techniques are common for diagnostic imaging and often supersede X-ray imaging in medical sectors. Recently studies for imaging smaller organs or surfaces, such as… (more)

▼ Ultrasound techniques are common for diagnostic imaging and often supersede X-ray imaging in medical sectors. Recently studies for imaging smaller organs or surfaces, such as skin, the gastrointestinal tract, and intravascular blood vessels, have emerged utilizing ultrasounds with frequencies over 20 MHz. A need remains for better clinical ultrasound imaging for detecting tumors and micro-sized tissues in vivo without the use of biopsy. In addition, a recent demand for portable ultrasound imaging systems in medical services has emerged. However, conventional ultrasound imaging systems have complicated electronics and high voltage transducers connected via bulky and expensive cables. Thus, over two decades many researchers have tried to miniaturize ultrasound imaging systems, and applied mixed-signal IC design techniques for integrating the front-end electronics on a single IC chip. However, no one has yet achieved an ultrasound imaging system with a fully integrated, custom-designed front-end IC chip that combines transmitters and receivers with high-resolution A/D converters and high-capacity on-chip memory devices. The proposed CMOS ultrasound transceiver chip enables development of portable high-resolution, high-frequency ultrasonic imaging systems. The transceiver chip design incorporates closed-coupled thin film ultrasound transducer array which operates with a 3.3 V power supply. In addition, a prototype chip, supported by digital beamforming system architecture, contains 16 receive and transmit channels with preamplifiers, Time-Gain compensation amplifiers, multiplexed Analog-to-Digital (A/D) converter with 3 Kbyte on-chip SRAM, and 50-MHz resolution time-delayed excitation pulse generators. By utilizing a shared A/D converter architecture, the numbers of A/D converters and SRAMs are reduced to one, although typical digital beamforming systems need 16 A/D converter for 16 receive channels. The carefully designed preamplifier minimizes stray capacitance and resistance between the transducers and the transceiver chip for ease of impedance matching and shows 100 MHz bandwidth at a gain of 20 dB. The VGA shows 23 dB linear gain, control range with 250 MHz bandwidth. The implemented TIQ ADC (Threshold Quantization Inverter A/D converter) achieves fast data conversion speed. Specified 6-bit resolution at a conversion speed of 250 MS/s was achieved. Further, this study presents a highly efficient TIQ comparator design methodology based on an analytical model for TIQ ADCs. The TIQ technique has gained importance in high speed flash A/D converters due to their fast data conversion speeds. The key to TIQ comparators’ designs is to generate different-sized TIQ comparators for an n-bit A/D converter; however, this technique is difficult and time-consuming for a higher-bit A/D converter. Thus, this thesis suggests a design algorithm based on MOSFET’s current SPICE model, and a customized program that automatically generates the TIQ comparators. The proposed methodology improves TIQ ADC design accuracy by 55% and reduces…

Subjects/Keywords: ultrasound imaging; analog-digital converter; Ultrasound transceiver

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APA (6^th Edition):

Kim, I. S. (2009). FULLY INTEGRATED CMOS ULTRASOUND TRANSCEIVER CHIP FOR HIGH-FREQUENCY HIGH-RESOLUTION ULTRASONIC IMAGING SYSTEMS. (Doctoral Dissertation). Penn State University. Retrieved from https://etda.libraries.psu.edu/catalog/9995

Chicago Manual of Style (16^th Edition):

Kim, In Soo. “FULLY INTEGRATED CMOS ULTRASOUND TRANSCEIVER CHIP FOR HIGH-FREQUENCY HIGH-RESOLUTION ULTRASONIC IMAGING SYSTEMS.” 2009. Doctoral Dissertation, Penn State University. Accessed October 19, 2019. https://etda.libraries.psu.edu/catalog/9995.

MLA Handbook (7^th Edition):

Kim, In Soo. “FULLY INTEGRATED CMOS ULTRASOUND TRANSCEIVER CHIP FOR HIGH-FREQUENCY HIGH-RESOLUTION ULTRASONIC IMAGING SYSTEMS.” 2009. Web. 19 Oct 2019.

Vancouver:

Kim IS. FULLY INTEGRATED CMOS ULTRASOUND TRANSCEIVER CHIP FOR HIGH-FREQUENCY HIGH-RESOLUTION ULTRASONIC IMAGING SYSTEMS. [Internet] [Doctoral dissertation]. Penn State University; 2009. [cited 2019 Oct 19]. Available from: https://etda.libraries.psu.edu/catalog/9995.

Council of Science Editors:

Kim IS. FULLY INTEGRATED CMOS ULTRASOUND TRANSCEIVER CHIP FOR HIGH-FREQUENCY HIGH-RESOLUTION ULTRASONIC IMAGING SYSTEMS. [Doctoral Dissertation]. Penn State University; 2009. Available from: https://etda.libraries.psu.edu/catalog/9995

University of Alberta

4. Sampaleanu, Alexander P. Top-Orthogonal-to-Bottom-Electrode Capacitive Micromachined Ultrasound Transducers for Low-Cost 3D Ultrasound Imaging.

Degree: MS, Department of Electrical and Computer Engineering, 2013, University of Alberta

URL: https://era.library.ualberta.ca/files/kw52j904w

► Capacitive micromachined ultrasound transducers (CMUTs) offer a promising solution for three-dimensional ultrasound imaging due to their ability to be easily fabricated in two-dimensional arrays. However,… (more)

Subjects/Keywords: MEMS; CMUT; Ultrasound; Imaging

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APA (6^th Edition):

Sampaleanu, A. P. (2013). Top-Orthogonal-to-Bottom-Electrode Capacitive Micromachined Ultrasound Transducers for Low-Cost 3D Ultrasound Imaging. (Masters Thesis). University of Alberta. Retrieved from https://era.library.ualberta.ca/files/kw52j904w

Chicago Manual of Style (16^th Edition):

Sampaleanu, Alexander P. “Top-Orthogonal-to-Bottom-Electrode Capacitive Micromachined Ultrasound Transducers for Low-Cost 3D Ultrasound Imaging.” 2013. Masters Thesis, University of Alberta. Accessed October 19, 2019. https://era.library.ualberta.ca/files/kw52j904w.

MLA Handbook (7^th Edition):

Sampaleanu, Alexander P. “Top-Orthogonal-to-Bottom-Electrode Capacitive Micromachined Ultrasound Transducers for Low-Cost 3D Ultrasound Imaging.” 2013. Web. 19 Oct 2019.

Vancouver:

Sampaleanu AP. Top-Orthogonal-to-Bottom-Electrode Capacitive Micromachined Ultrasound Transducers for Low-Cost 3D Ultrasound Imaging. [Internet] [Masters thesis]. University of Alberta; 2013. [cited 2019 Oct 19]. Available from: https://era.library.ualberta.ca/files/kw52j904w.

Council of Science Editors:

Sampaleanu AP. Top-Orthogonal-to-Bottom-Electrode Capacitive Micromachined Ultrasound Transducers for Low-Cost 3D Ultrasound Imaging. [Masters Thesis]. University of Alberta; 2013. Available from: https://era.library.ualberta.ca/files/kw52j904w

University of Alberta

5. Zhang, Chan. Application of Ultrasound to Guide Pedicle Screw Insertion during Scoliosis Surgery: a Feasibility Study.

Degree: MS, Radiology and Diagnostic Imaging, 2010, University of Alberta

URL: https://era.library.ualberta.ca/files/4f16c425j

► This thesis presents an experimental study of a bovine vertebra using transmission and pulse-echo methods and a preliminary investigation to guide a screw insertion into… (more)

Subjects/Keywords: Bone Imaging; Ultrasound; Scoliosis Surgery

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APA (6^th Edition):

Zhang, C. (2010). Application of Ultrasound to Guide Pedicle Screw Insertion during Scoliosis Surgery: a Feasibility Study. (Masters Thesis). University of Alberta. Retrieved from https://era.library.ualberta.ca/files/4f16c425j

Chicago Manual of Style (16^th Edition):

Zhang, Chan. “Application of Ultrasound to Guide Pedicle Screw Insertion during Scoliosis Surgery: a Feasibility Study.” 2010. Masters Thesis, University of Alberta. Accessed October 19, 2019. https://era.library.ualberta.ca/files/4f16c425j.

MLA Handbook (7^th Edition):

Zhang, Chan. “Application of Ultrasound to Guide Pedicle Screw Insertion during Scoliosis Surgery: a Feasibility Study.” 2010. Web. 19 Oct 2019.

Vancouver:

Zhang C. Application of Ultrasound to Guide Pedicle Screw Insertion during Scoliosis Surgery: a Feasibility Study. [Internet] [Masters thesis]. University of Alberta; 2010. [cited 2019 Oct 19]. Available from: https://era.library.ualberta.ca/files/4f16c425j.

Council of Science Editors:

Zhang C. Application of Ultrasound to Guide Pedicle Screw Insertion during Scoliosis Surgery: a Feasibility Study. [Masters Thesis]. University of Alberta; 2010. Available from: https://era.library.ualberta.ca/files/4f16c425j

Georgia Tech

6. Satir, Sarp. Modeling and optimization of capacitive micromachined ultrasonic transducers.

Degree: PhD, Electrical and Computer Engineering, 2014, Georgia Tech

URL: http://hdl.handle.net/1853/54303

► The objective of this research is to develop large signal modeling and optimization methods for Capacitive Micromachined Ultrasonic Transducers (CMUTs), especially when they are used… (more)

▼ The objective of this research is to develop large signal modeling and optimization methods for Capacitive Micromachined Ultrasonic Transducers (CMUTs), especially when they are used in an array configuration. General modeling and optimization methods that cover a large domain of CMUT designs are crucial, as many membrane and array geometry combinations are possible using existing microfabrication technologies. Currently, large signal modeling methods for CMUTs are not well established and nonlinear imaging techniques utilizing linear piezoelectric transducers are not applicable to CMUTs because of their strong nonlinearity. In this work, the nonlinear CMUT behavior is studied, and a feedback linearization method is proposed to reduce the CMUT nonlinearity. This method is shown to improve the CMUT performance for continuous wave applications, such as high-intensity focused ultrasound or harmonic imaging, where transducer linearity is crucial. In the second part of this dissertation, a large signal model is developed that is capable of transient modeling of CMUT arrays with arbitrary electrical terminations. The developed model is suitable for iterative design optimization of CMUTs and CMUT based imaging systems with arbitrary membrane and array geometries for a variety of applications. Finally, a novel multi-pulse method for nonlinear tissue and contrast agent imaging with CMUTs is presented. It is shown that the nonlinear content can be successfully extracted from echo signals in a CMUT based imaging system using a multiple pulse scheme. The proposed method is independent of the CMUT geometry and valid for large signal operation. Experimental results verifying the developed large signal CMUT array model, proposed gap feedback and multi-pulse techniques are also presented. Advisors/Committee Members: Degertekin, F. Levent (advisor), Brand, Oliver (committee member), Sabra, Karim (committee member), Ghovanloo, Maysam (committee member), Bhatti, Pamela (committee member).

Subjects/Keywords: CMUTs; Ultrasound imaging; Nonlinear modeling

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APA (6^th Edition):

Satir, S. (2014). Modeling and optimization of capacitive micromachined ultrasonic transducers. (Doctoral Dissertation). Georgia Tech. Retrieved from http://hdl.handle.net/1853/54303

Chicago Manual of Style (16^th Edition):

Satir, Sarp. “Modeling and optimization of capacitive micromachined ultrasonic transducers.” 2014. Doctoral Dissertation, Georgia Tech. Accessed October 19, 2019. http://hdl.handle.net/1853/54303.

MLA Handbook (7^th Edition):

Satir, Sarp. “Modeling and optimization of capacitive micromachined ultrasonic transducers.” 2014. Web. 19 Oct 2019.

Vancouver:

Satir S. Modeling and optimization of capacitive micromachined ultrasonic transducers. [Internet] [Doctoral dissertation]. Georgia Tech; 2014. [cited 2019 Oct 19]. Available from: http://hdl.handle.net/1853/54303.

Council of Science Editors:

Satir S. Modeling and optimization of capacitive micromachined ultrasonic transducers. [Doctoral Dissertation]. Georgia Tech; 2014. Available from: http://hdl.handle.net/1853/54303

McMaster University

7. Smail, Lauren. Investigating the Use of Convolutional Neural Networks for Prenatal Hydronephrosis Ultrasound Image Classification.

Degree: MSc, 2018, McMaster University

URL: http://hdl.handle.net/11375/24122

►

Prenatal hydronephrosis is a common condition that involves the accumulation of urine with consequent dilatation of the collecting system in fetal infants. There are several… (more)

▼

Prenatal hydronephrosis is a common condition that involves the accumulation of urine with consequent dilatation of the collecting system in fetal infants. There are several hydronephrosis classifications, however, all grading systems suffer from reliability issues as they contain subjective criteria. The severity of hydronephrosis impacts treatment and follow up times and can therefore directly influence a patient’s well-being and quality of care. Considering the importance of accurate diagnosis, it is concerning that no accurate, reliable or objective grading system exists. We believe that developing a convolutional neural network (CNN) based diagnostic aid for hydronephrosis will improve physicians’ objectivity, inter-rater reliability and accuracy. Developing CNN based diagnostic aid for ultrasound images has not been done before. Therefore, the current thesis conducted two studies using a database of 4670 renal ultrasound images to investigate two important methodological considerations: ultrasound image preprocessing and model architecture. We first investigated whether image segmentation and textural extraction are beneficial and improve performance when they are applied to CNN input images. Our results showed that neither preprocessing technique improved performance, and therefore might not be required when using CNN for ultrasound image classification. Our search for an optimal architecture resulted in a model with 49% 5-way classification accuracy. Further investigation revealed that images in our database had been mislabelled, and thus impacted model training and testing. Although our current best model is not ready for use as diagnostic aid, it can be used to verify the accuracy of our labels. Overall, these studies have provided insight into developing a diagnostic aid for hydronephrosis. Once our images and their respective labels have been verified, we can further optimize our model architecture by conducting an exhaustive search. We hypothesize that these two changes will significantly improve model performance and bring our diagnostic aid closer to clinical application.

Thesis

Master of Science (MSc)

Prenatal hydronephrosis is a serious condition that affects the kidneys of fetal infants and is graded using renal ultrasound. The severity of hydronephrosis impacts treatment and follow-up times. However, all grading systems suffer from reliability issues. Improving diagnostic reliability is important for patient well-being. We believe that developing a computer-based diagnostic aid is a promising option to do so. We conducted two studies to investigate how ultrasound images should be processed, and how the algorithm that produces the functionality of the aid should be designed. We found that two common recommendations for ultrasound processing did not improve model performance and therefore need not be applied. Our best performing algorithm had a classification accuracy of 49%. However, we found that several images in our database were mislabelled, which impacted accuracy metrics. Once…

Advisors/Committee Members: Sonnadara, Ranil, Becker, Suzanna, Psychology.

Subjects/Keywords: Machine learning; Medical imaging; Ultrasound

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APA (6^th Edition):

Smail, L. (2018). Investigating the Use of Convolutional Neural Networks for Prenatal Hydronephrosis Ultrasound Image Classification. (Masters Thesis). McMaster University. Retrieved from http://hdl.handle.net/11375/24122

Chicago Manual of Style (16^th Edition):

Smail, Lauren. “Investigating the Use of Convolutional Neural Networks for Prenatal Hydronephrosis Ultrasound Image Classification.” 2018. Masters Thesis, McMaster University. Accessed October 19, 2019. http://hdl.handle.net/11375/24122.

MLA Handbook (7^th Edition):

Smail, Lauren. “Investigating the Use of Convolutional Neural Networks for Prenatal Hydronephrosis Ultrasound Image Classification.” 2018. Web. 19 Oct 2019.

Vancouver:

Smail L. Investigating the Use of Convolutional Neural Networks for Prenatal Hydronephrosis Ultrasound Image Classification. [Internet] [Masters thesis]. McMaster University; 2018. [cited 2019 Oct 19]. Available from: http://hdl.handle.net/11375/24122.

Council of Science Editors:

Smail L. Investigating the Use of Convolutional Neural Networks for Prenatal Hydronephrosis Ultrasound Image Classification. [Masters Thesis]. McMaster University; 2018. Available from: http://hdl.handle.net/11375/24122

Boston University

8. Subaran, Sarah Samira. A visual comparison between the Ultrasound X6-1 Matrix transducer and MRI in lesion detection in the dome of the liver.

Degree: MS, Bioimaging, 2014, Boston University

URL: http://hdl.handle.net/2144/14393

► Imaging the dome of the liver can be a very challenging area to image by Ultrasound. Due to its position inside the ribcage there can… (more)

Subjects/Keywords: Medical imaging; Imaging; Liver; MRI; Ultrasound

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APA (6^th Edition):

Subaran, S. S. (2014). A visual comparison between the Ultrasound X6-1 Matrix transducer and MRI in lesion detection in the dome of the liver. (Masters Thesis). Boston University. Retrieved from http://hdl.handle.net/2144/14393

Chicago Manual of Style (16^th Edition):

Subaran, Sarah Samira. “A visual comparison between the Ultrasound X6-1 Matrix transducer and MRI in lesion detection in the dome of the liver.” 2014. Masters Thesis, Boston University. Accessed October 19, 2019. http://hdl.handle.net/2144/14393.

MLA Handbook (7^th Edition):

Subaran, Sarah Samira. “A visual comparison between the Ultrasound X6-1 Matrix transducer and MRI in lesion detection in the dome of the liver.” 2014. Web. 19 Oct 2019.

Vancouver:

Subaran SS. A visual comparison between the Ultrasound X6-1 Matrix transducer and MRI in lesion detection in the dome of the liver. [Internet] [Masters thesis]. Boston University; 2014. [cited 2019 Oct 19]. Available from: http://hdl.handle.net/2144/14393.

Council of Science Editors:

Subaran SS. A visual comparison between the Ultrasound X6-1 Matrix transducer and MRI in lesion detection in the dome of the liver. [Masters Thesis]. Boston University; 2014. Available from: http://hdl.handle.net/2144/14393

University of Oxford

9. Rademeyer, Paul. A new technique for microbubble characterisation and the implications to contrast enhanced ultrasound.

Degree: PhD, 2016, University of Oxford

URL: https://ora.ox.ac.uk/objects/uuid:2f5b0002-83e0-4251-b69a-de78c9895277 ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.730488

► The utility of microbubble agents in a variety of diagnostic and therapeutic ultrasound techniques has been widely demonstrated, most notably in Contrast Enhanced Ultrasound (CEUS)… (more)

▼ The utility of microbubble agents in a variety of diagnostic and therapeutic ultrasound techniques has been widely demonstrated, most notably in Contrast Enhanced Ultrasound (CEUS) imaging. Unfortunately, the underlying mechanisms of their response to ultrasound excitation are poorly understood, restricting the development of promising techniques, such as quantitative perfusion imaging. A significant reason for this is that current microbubble characterisation techniques suffer from one or more of the following limitations: i) large experimental uncertainties, ii) physical restrictions on microbubble response and iii) failure to provide large data sets suitable for statistical analysis. This thesis presents a new technique to overcome these limitations. A co-axial microfluidic device is used to hydrodynamically confine microbubbles through the focal region of a laser and ultrasound field. The magnitude of light scattered by isolated microbubbles during ultrasound excitation is converted to radius using Mie Scattering theory. This technique is capable of obtaining large samples (>10³/min) of microbubbles to be efficiently characterised. The response of a commercial contrast agent, SonoVue®, is first investigated for a range of ultrasound exposure parameters; frequency (2 MHz - 4.5 MHz), peak negative pressure (6 kPa - 400 kPa) and pulse length (3 cycles - 8 cycles). Second the device is used to investigate the effect of composition and fabrication on microbubble response to similar ultrasound conditions. The results demonstrate a very large variability in microbubble response independent of initial size, indicating a significant lack of uniformity of coating properties. This is further supported by quantitative fluorescence imaging and quasi-static pressure chamber measurements. The implications of the findings for CEUS imaging and the development of microbubble contrast agents are discussed, as well as the limitations and suggested improvements of the characterisation technique.

Subjects/Keywords: Ultrasound Imaging; Biomedical engineering; Contrast Enhanced Ultrasound; Ultrasound Contrast Agents; Microbubbles; Characterisation; Ultrasound

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APA (6^th Edition):

Rademeyer, P. (2016). A new technique for microbubble characterisation and the implications to contrast enhanced ultrasound. (Doctoral Dissertation). University of Oxford. Retrieved from https://ora.ox.ac.uk/objects/uuid:2f5b0002-83e0-4251-b69a-de78c9895277 ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.730488

Chicago Manual of Style (16^th Edition):

Rademeyer, Paul. “A new technique for microbubble characterisation and the implications to contrast enhanced ultrasound.” 2016. Doctoral Dissertation, University of Oxford. Accessed October 19, 2019. https://ora.ox.ac.uk/objects/uuid:2f5b0002-83e0-4251-b69a-de78c9895277 ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.730488.

MLA Handbook (7^th Edition):

Rademeyer, Paul. “A new technique for microbubble characterisation and the implications to contrast enhanced ultrasound.” 2016. Web. 19 Oct 2019.

Vancouver:

Rademeyer P. A new technique for microbubble characterisation and the implications to contrast enhanced ultrasound. [Internet] [Doctoral dissertation]. University of Oxford; 2016. [cited 2019 Oct 19]. Available from: https://ora.ox.ac.uk/objects/uuid:2f5b0002-83e0-4251-b69a-de78c9895277 ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.730488.

Council of Science Editors:

Rademeyer P. A new technique for microbubble characterisation and the implications to contrast enhanced ultrasound. [Doctoral Dissertation]. University of Oxford; 2016. Available from: https://ora.ox.ac.uk/objects/uuid:2f5b0002-83e0-4251-b69a-de78c9895277 ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.730488

Queensland University of Technology

10. Khoei, Shadi. Quantitative ultrasound computed tomography imaging of PAGAT radiation dosimetry gel.

Degree: 2013, Queensland University of Technology

URL: https://eprints.qut.edu.au/63958/

► This research developed and scientifically validated a new ultrasound transmission computed tomography system with the aim of quantitative assessment of a polymer gel dosimeter including… (more)

Subjects/Keywords: Ultrasound computed tomography; Ultrasound attenuation; Broadband ultrasound attenuation; Ultrasound imaging; Polymer gel dosimetry

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APA (6^th Edition):

Khoei, S. (2013). Quantitative ultrasound computed tomography imaging of PAGAT radiation dosimetry gel. (Thesis). Queensland University of Technology. Retrieved from https://eprints.qut.edu.au/63958/

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Khoei, Shadi. “Quantitative ultrasound computed tomography imaging of PAGAT radiation dosimetry gel.” 2013. Thesis, Queensland University of Technology. Accessed October 19, 2019. https://eprints.qut.edu.au/63958/.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Khoei, Shadi. “Quantitative ultrasound computed tomography imaging of PAGAT radiation dosimetry gel.” 2013. Web. 19 Oct 2019.

Vancouver:

Khoei S. Quantitative ultrasound computed tomography imaging of PAGAT radiation dosimetry gel. [Internet] [Thesis]. Queensland University of Technology; 2013. [cited 2019 Oct 19]. Available from: https://eprints.qut.edu.au/63958/.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Khoei S. Quantitative ultrasound computed tomography imaging of PAGAT radiation dosimetry gel. [Thesis]. Queensland University of Technology; 2013. Available from: https://eprints.qut.edu.au/63958/

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Southern California

11. Ma, Teng. Multi-modality intravascular imaging by combined use of ultrasonic and opticial techniques.

Degree: PhD, Biomedical Engineering, 2017, University of Southern California

URL: http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll3/id/616089/rec/4247

► Thin-capped fibroatheroma (TCFA) is considered to be the phenotype of vulnerable atherosclerotic plaque based on the pathological studies, whose sudden rupture is frequently responsible for… (more)

▼ Thin-capped fibroatheroma (TCFA) is considered to be the phenotype of vulnerable atherosclerotic plaque based on the pathological studies, whose sudden rupture is frequently responsible for acute coronary syndrome (ACS). Early detection and prognosis of TCFA will not only guide the therapeutic strategy to benefit the patients, but also contribute to the study of natural history of vulnerable plaque that is still elusive. To date, various imaging modalities employing ultrasonic scattering contrast with radio frequency analysis, optical scattering contrast, optical absorption mechanism, spectroscopic analysis and targeted-molecular imaging method, provide diverse visualizations of coronary arteries both in clinic and research. However, none of these imaging modalities has been symmetrically validated to precisely detect TCFA in vivo, since any single imaging modality exhibit natural limitations when characterizing the elusive TCFA. Therefore, integration of theses imaging modalities into a single catheter is hypothesized to be the optimal method to enable the early detection of TCFA by combing best features of these techniques while compensating their respective weakness. ❧ In this thesis, several multi-modality intravascular imaging systems by combined use of ultrasonic and optical techniques were developed in three aspects to access the morphological information, functional components, and elasticity of coronary arteries. Aim to fully obtain the morphological information real time in vivo, an ultra-high speed integrated intravascular ultrasound (IVUS) and optical coherence tomography (OCT) system has been optimized and prototyped. Statistical validation study and IVUS-OCT diagnostic criteria development has demonstrated that the integrated IVUS-OCT system has an overall higher diagnostic accuracy of atherosclerotic plaques, especially for lipid-rich plaques. From the cost-effective perspectives, a multi-frequency IVUS imaging system was developed to improve the trade-off between resolution and depth of penetration of IVUS. Aiming to measure the thin fibrous cap, an ultra-high frequency IVUS transducer was incorporated into the conventional IVUS catheter to provide higher special resolution image of the coronary artery, which makes the multi-frequency IVUS imaging system an alternative of integrated IVUS-OCT system. Moreover, the development of a high speed integrated IVUS and intravascular photoacoustic (IVPA) system make it possible to quantify a key parameter of diagnosing TCFA—the size of lipid deposition inside coronary artery. In vitro imaging of lipid-laden artery was performed by using current IVUS-IVPA system with 2 orders of magnitude improvement of imaging speed, which bridged the gap of translating the IVUS-IVPA technology to clinical study. In order to characterized the biomechanical properties of plaque components, acoustic radiation force (ARF) optical coherence elastography (OCE) is further developed featured by the confocal alignment of OCT detection region with acoustic excitation field. Based on the… Advisors/Committee Members: Shung, Kirk KopingZhou, Qifa (Committee Chair), Yen, Jesse (Committee Member), Armani, Andrea M. (Committee Member), McCain, Megan (Committee Member).

Subjects/Keywords: atherosclerosis; intravascular imaging; intravascular ultrasound; high frequency ultrasound; multi-modality imaging; photoacoustic imaging

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APA (6^th Edition):

Ma, T. (2017). Multi-modality intravascular imaging by combined use of ultrasonic and opticial techniques. (Doctoral Dissertation). University of Southern California. Retrieved from http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll3/id/616089/rec/4247

Chicago Manual of Style (16^th Edition):

Ma, Teng. “Multi-modality intravascular imaging by combined use of ultrasonic and opticial techniques.” 2017. Doctoral Dissertation, University of Southern California. Accessed October 19, 2019. http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll3/id/616089/rec/4247.

MLA Handbook (7^th Edition):

Ma, Teng. “Multi-modality intravascular imaging by combined use of ultrasonic and opticial techniques.” 2017. Web. 19 Oct 2019.

Vancouver:

Ma T. Multi-modality intravascular imaging by combined use of ultrasonic and opticial techniques. [Internet] [Doctoral dissertation]. University of Southern California; 2017. [cited 2019 Oct 19]. Available from: http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll3/id/616089/rec/4247.

Council of Science Editors:

Ma T. Multi-modality intravascular imaging by combined use of ultrasonic and opticial techniques. [Doctoral Dissertation]. University of Southern California; 2017. Available from: http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll3/id/616089/rec/4247

12. Reddy, Vaka Narasimha. Comparison and Optimization of Insonation Strategies for Contrast Enhanced Ultrasound Imaging.

Degree: The Institute of Technology, 2012, Linköping UniversityLinköping University

URL: http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-76646

► Evolution of vulnerable carotid plaques are crucial reason for cerebral ischemic strokes and identifying them in the early stage can become very important in… (more)

Subjects/Keywords: Introduction to Medical Ultrasound; Ultrasound Contrast Agents; Ultrasound Contrast for Carotid Plaques; Contrast enhanced ultrasound imaging; Bubble Theory; Nonlinear imaging; Ultrasound imaging; Pulse inversion; Cadence contrast pulse sequence

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APA (6^th Edition):

Reddy, V. N. (2012). Comparison and Optimization of Insonation Strategies for Contrast Enhanced Ultrasound Imaging. (Thesis). Linköping UniversityLinköping University. Retrieved from http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-76646

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Reddy, Vaka Narasimha. “Comparison and Optimization of Insonation Strategies for Contrast Enhanced Ultrasound Imaging.” 2012. Thesis, Linköping UniversityLinköping University. Accessed October 19, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-76646.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Reddy, Vaka Narasimha. “Comparison and Optimization of Insonation Strategies for Contrast Enhanced Ultrasound Imaging.” 2012. Web. 19 Oct 2019.

Vancouver:

Reddy VN. Comparison and Optimization of Insonation Strategies for Contrast Enhanced Ultrasound Imaging. [Internet] [Thesis]. Linköping UniversityLinköping University; 2012. [cited 2019 Oct 19]. Available from: http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-76646.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Reddy VN. Comparison and Optimization of Insonation Strategies for Contrast Enhanced Ultrasound Imaging. [Thesis]. Linköping UniversityLinköping University; 2012. Available from: http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-76646

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Edinburgh

13. Thomas, David H. Acoustic investigation of microbubble response to medical imaging ultrasound pulses.

Degree: PhD, 2010, University of Edinburgh

URL: http://hdl.handle.net/1842/4516

► Ultrasound contrast agents have the ability to provide locally increased echogenicity, improving the sensitivity and specificity of images. Due to the unique interaction of microbubbles… (more)

▼ Ultrasound contrast agents have the ability to provide locally increased echogenicity, improving the sensitivity and specificity of images. Due to the unique interaction of microbubbles with the imaging ultrasound field, contrast ultrasonography offers both improved diagnostic techniques, and the potential therapeutic uses of gene and drug delivery through the use of targeted agents. By enhancing the contrast at the tissue-blood interface, an improved image of the structure of organs can be achieved, which is useful in many areas of medical ultrasound imaging. Monitoring the flow of contrast agent in the blood stream also offers information on the degree of blood perfusion into an organ or microvasculature. Present knowledge of the interaction of microbubbles with ultrasound is far from complete. The full potential of contrast agents in improving diagnostic and therapeutic techniques has therefore not yet been achieved. The nonlinear and dynamic properties of microbubble response offer potentially large improvements in contrast to tissue ratio, through intelligent pulse sequence design and/or improved signal processing. Due to various drawbacks of populations studies, only by studying the response from single microbubbles can the interaction be fully understood. The variations of microbubble size and shell parameters within a typical sample of contrast agent dictate that a large number of single scatterer data are necessary to obtain information on the variability of microbubble response, which is not possible with current optical systems. This thesis aims to be a contribution to the understanding of contrast behaviour in response to medical imaging ultrasound pulses. A fully characterized microacoustic system, employing a wide-band piezoelectric transducer from a commercial ultrasound imaging system, is introduced, which enables the measurement of single scattering events. Single microbubble signals from two commercially available contrast agents, Definity R and biSphereTM, have been measured experimentally in response to a range of clinically relevant imaging parameters. The data has been analyzed, together with the results from appropriate theoretical models, in order to gain physical insight into the evolution and dynamics of microbubble signals. A theoretical model for the lipid shelled agent Definity has been developed, and the predicted response from a real sample of single microbubbles investigated. Various characteristics of resonant scatter have been identified, and used to distinguish resonant scatter in experimental acoustic single bubble data for the first time. A clear distinction between the populations of resonant and off-resonant scatter has been observed for a range of incident frequencies and acoustic pressures. Results from consecutive imaging pulses have been used to gain understanding of how initial size, shell material and encapsulated gas may effect the lifetime of a microbubble signal. The response to a basic pulse sequence is also investigated, and an alternative processing method which…

Subjects/Keywords: 534; ultrasound; medical imaging; microbubbles; resonance

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Thomas, D. H. (2010). Acoustic investigation of microbubble response to medical imaging ultrasound pulses. (Doctoral Dissertation). University of Edinburgh. Retrieved from http://hdl.handle.net/1842/4516

Chicago Manual of Style (16^th Edition):

Thomas, David H. “Acoustic investigation of microbubble response to medical imaging ultrasound pulses.” 2010. Doctoral Dissertation, University of Edinburgh. Accessed October 19, 2019. http://hdl.handle.net/1842/4516.

MLA Handbook (7^th Edition):

Thomas, David H. “Acoustic investigation of microbubble response to medical imaging ultrasound pulses.” 2010. Web. 19 Oct 2019.

Vancouver:

Thomas DH. Acoustic investigation of microbubble response to medical imaging ultrasound pulses. [Internet] [Doctoral dissertation]. University of Edinburgh; 2010. [cited 2019 Oct 19]. Available from: http://hdl.handle.net/1842/4516.

Council of Science Editors:

Thomas DH. Acoustic investigation of microbubble response to medical imaging ultrasound pulses. [Doctoral Dissertation]. University of Edinburgh; 2010. Available from: http://hdl.handle.net/1842/4516

University of Utah

14. Dillon, Christopher Reed. Identifying parameters from the bioheat transfer equation using magnetic resonance-guided focused uotrasound.

Degree: PhD, Bioengineering, 2014, University of Utah

URL: http://content.lib.utah.edu/cdm/singleitem/collection/etd3/id/3186/rec/1287

► For magnetic resonance-guided focused ultrasound (MRgFUS) treatments to be broadly accepted, progress must be made in treatment planning, monitoring, and control. A key component to… (more)

▼ For magnetic resonance-guided focused ultrasound (MRgFUS) treatments to be broadly accepted, progress must be made in treatment planning, monitoring, and control. A key component to this goal is accurate modeling of the bioheat transfer equation (BHTE). This dissertation develops new methods for identifying the significant parameters of the BHTE: the ultrasonic specific absorption rate (SAR), the tissue thermaldiffusivity, and perfusion-related energy losses. SAR is determined by fitting an analytical solution one-dimensional radial Gaussian heating) to MRgFUS temperature data in simulations and a tissue-mimicking phantom. This new method is compared with linear and exponential methods for different fitting times, beam sizes, perfusion, and thermal diffusivity values. The analytical method is consistently most reliable and is accurate to within 10% for all cases, except highperfusion. An extension to the analytical solution improves SAR estimates for high perfusion cases.MRgFUS sampling characteristics (spatial averaging, temporal sampling, and noise) for SAR and thermal diffusivity estimation are parametrically evaluated against several focused ultrasound beam sizes. For single point heatings, a maximum voxel size of1x1x3 mm is recommended for temperature and estimate errors to remain less than 10%. Two MRgFUS thermal diffusivity estimation methods are evaluated against a standard technique in ex vivo porcine and in vivo rabbit back muscle. Both methods accurately estimate thermal diffusivity using cooling data (overall ex vivo error < 6%, in vivo < 12%). Including heating data in the Gaussian SAR method further reduces errors(ex vivo error < 2%, in vivo < 3%). The Gaussian SAR method has better precision than the Gaussian temperature method.Two methods for quantifying perfusion-related energy losses using MRgFUS cooling temperatures are developed (experimental + modeled data vs. experimental data). The methods are verified via simulations and experiments in ex vivo perfused porcine kidney at different flow rates. The difference techniques employed make these methods susceptible to noise errors, but this feasibility study demonstrates promise for their use in future work.In conclusion, these methods can be used to validate biothermal models, and associated improvements in thermal modeling have the potential to increase the efficacy and safety of MRgFUS therapies.

Subjects/Keywords: Bioheat transfer; Focused ultrasound; Magnetic resonance imaging

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APA (6^th Edition):

Dillon, C. R. (2014). Identifying parameters from the bioheat transfer equation using magnetic resonance-guided focused uotrasound. (Doctoral Dissertation). University of Utah. Retrieved from http://content.lib.utah.edu/cdm/singleitem/collection/etd3/id/3186/rec/1287

Chicago Manual of Style (16^th Edition):

Dillon, Christopher Reed. “Identifying parameters from the bioheat transfer equation using magnetic resonance-guided focused uotrasound.” 2014. Doctoral Dissertation, University of Utah. Accessed October 19, 2019. http://content.lib.utah.edu/cdm/singleitem/collection/etd3/id/3186/rec/1287.

MLA Handbook (7^th Edition):

Dillon, Christopher Reed. “Identifying parameters from the bioheat transfer equation using magnetic resonance-guided focused uotrasound.” 2014. Web. 19 Oct 2019.

Vancouver:

Dillon CR. Identifying parameters from the bioheat transfer equation using magnetic resonance-guided focused uotrasound. [Internet] [Doctoral dissertation]. University of Utah; 2014. [cited 2019 Oct 19]. Available from: http://content.lib.utah.edu/cdm/singleitem/collection/etd3/id/3186/rec/1287.

Council of Science Editors:

Dillon CR. Identifying parameters from the bioheat transfer equation using magnetic resonance-guided focused uotrasound. [Doctoral Dissertation]. University of Utah; 2014. Available from: http://content.lib.utah.edu/cdm/singleitem/collection/etd3/id/3186/rec/1287

University of Southern California

15. Park, Jinhyoung. High frequency chirp coded excitation ultrasound imaging system.

Degree: PhD, Biomedical Engineering, 2011, University of Southern California

URL: http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll127/id/664082/rec/3164

► An increase of imaging frequency enhances the performance in spatial resolution of an ultrasound scanner while sacrificing echo signal to noise ratio (eSNR) because of… (more)

▼ An increase of imaging frequency enhances the performance in spatial resolution of an ultrasound scanner while sacrificing echo signal to noise ratio (eSNR) because of a rise in the amount of attenuation. As solutions to raise the eSNR level while maintaining the enhanced spatial resolution, both fundamental and harmonic coded excitation imaging methods have been proposed. For this purpose, ultrasound bio-microscopes (UBM) capable of chirp coded excitations were implemented on both a linear and a sector mechanical scanning system. A custom-designed broadband (5 MHz – 140 MHz) linear power amplifier was designed as a part of a low noise arbitrary pulse generator to replace a commercial bench-top power amplifier in the linear UBM. The modified imaging system exhibited a better eSNR of 7 dB than the system with a commercial power amplifier while maintaining the spatial resolution in a wire target measurement. In-vivo imaging was carried on pig eye and zebrafish embryo using a 40 MHz and a 100 MHz single element transducer respectively. For high frame rate coded excitation imaging, a standalone frontend system for a sector UBM was implemented. The custom-designed system consisting of a transmitter, a receiver, a motor controller and a motor position interpreter achieved an eSNR of 66 dB utilizing chirp coded excitation for wire target imaging. Moreover, contrast to noise ratio (CNR) was improved from 2.92 to 3.18 with coded excitation. This modified scanner allowed contraction of cardiac chambers of both zebrafish and mouse hearts to be clearly visualized. As an effort to enhance the spatial resolution, pulse inversion chirp coded tissue harmonic imaging (PI-CTHI) was programmed into the custom-designed frontend system. In a wire target study using a 40 MHz single element transducer, lateral resolution was found to be 110 μm, which was narrower than fundamental imaging at153 μm. CNR was found to improve by 34 % when chirp coded excitation was applied to harmonic imaging. This imaging mode was shown to better delineate the clot formation in adult zebrafish heart imaging when the heart was amputated and allowed to regenerate. Advisors/Committee Members: Yen, Jesse T.Hsiai, Tzung K.Kuo, C.-C. JayShung, K. Kirk (Committee Chair).

Subjects/Keywords: high frequency ultrasound imaging; chirp coded excitation

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APA (6^th Edition):

Park, J. (2011). High frequency chirp coded excitation ultrasound imaging system. (Doctoral Dissertation). University of Southern California. Retrieved from http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll127/id/664082/rec/3164

Chicago Manual of Style (16^th Edition):

Park, Jinhyoung. “High frequency chirp coded excitation ultrasound imaging system.” 2011. Doctoral Dissertation, University of Southern California. Accessed October 19, 2019. http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll127/id/664082/rec/3164.

MLA Handbook (7^th Edition):

Park, Jinhyoung. “High frequency chirp coded excitation ultrasound imaging system.” 2011. Web. 19 Oct 2019.

Vancouver:

Park J. High frequency chirp coded excitation ultrasound imaging system. [Internet] [Doctoral dissertation]. University of Southern California; 2011. [cited 2019 Oct 19]. Available from: http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll127/id/664082/rec/3164.

Council of Science Editors:

Park J. High frequency chirp coded excitation ultrasound imaging system. [Doctoral Dissertation]. University of Southern California; 2011. Available from: http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll127/id/664082/rec/3164

University of Victoria

16. Albulayli, Mohammed. Migration-based image reconstruction methods for plane-wave ultrasound imaging.

Degree: Department of Electrical and Computer Engineering, 2018, University of Victoria

URL: https://dspace.library.uvic.ca//handle/1828/9879

► Ultrasound imaging plays an important role in biomedical diagnostics due its safety, noninvasive nature, and low cost. Conventional ultrasound systems typically form an image frame… (more)

▼ Ultrasound imaging plays an important role in biomedical diagnostics due its safety, noninvasive nature, and low cost. Conventional ultrasound systems typically form an image frame by scanning the region of interest line-by-line, using a focused beam during transmission and dynamic focusing during reception. Alternatively, the region of interest can be insonified at once using a plane wave, which allows for ultrafast data acquisition rates but reduces the resulting image quality. The latter can be improved by means of coherent plane-wave compounding (CPWC), whereby multiple plane waves are emitted at different angles to obtain multiple image datasets that are subsequently combined to enhance the final compounded image. We present two novel Fourier-domain techniques for CPWC image reconstruction from raw linear-array sensor data. In particular, we show how to modify two classic algorithms used for geophysical data processing, namely Stolt's and slant-stack depth migration under zero-offset constant-velocity assumptions, so that their new versions become applicable to plane-wave ultrasound data processing. To demonstrate the merits and limitations of our approach, we provide qualitative and quantitative comparisons with other Fourier-domain methods reported in the ultrasound literature. Our evaluation results are based on the image resolution, contrast, and similarity metrics obtained for several public-domain experimental benchmark datasets. We also describe another novel Fourier-domain method for CPWC image reconstruction that can be used in situations where the speed of sound varies with depth in a layered propagation medium. Our technique builds on Gazdag's phase-shift migration algorithm that has been modified to handle plane-wave ultrasound data processing. Our simulation results show that the proposed method is capable of accurately imaging point targets in a three-layer medium, mimicking tissue-bone-tissue ultrasound propagation. Advisors/Committee Members: Rakhmatov, Daler N. (supervisor).

Subjects/Keywords: Ultrasound imaging; biomedical diagnostics; CPWC image reconstruction

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APA (6^th Edition):

Albulayli, M. (2018). Migration-based image reconstruction methods for plane-wave ultrasound imaging. (Thesis). University of Victoria. Retrieved from https://dspace.library.uvic.ca//handle/1828/9879

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Albulayli, Mohammed. “Migration-based image reconstruction methods for plane-wave ultrasound imaging.” 2018. Thesis, University of Victoria. Accessed October 19, 2019. https://dspace.library.uvic.ca//handle/1828/9879.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Albulayli, Mohammed. “Migration-based image reconstruction methods for plane-wave ultrasound imaging.” 2018. Web. 19 Oct 2019.

Vancouver:

Albulayli M. Migration-based image reconstruction methods for plane-wave ultrasound imaging. [Internet] [Thesis]. University of Victoria; 2018. [cited 2019 Oct 19]. Available from: https://dspace.library.uvic.ca//handle/1828/9879.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Albulayli M. Migration-based image reconstruction methods for plane-wave ultrasound imaging. [Thesis]. University of Victoria; 2018. Available from: https://dspace.library.uvic.ca//handle/1828/9879

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

17. Vos, Rik. Single Microbubble Imaging.

Degree: 2010, Erasmus University Medical Center

URL: http://hdl.handle.net/1765/17804

► textabstractThe imaging of smaller vessels and organ perfusion has high clinical value for the di¬agnosis of cardiovascular disorders and cancer. Ultrasound imaging is the most… (more)

Subjects/Keywords: imaging; microbubbles; ultrasound

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APA (6^th Edition):

Vos, R. (2010). Single Microbubble Imaging. (Doctoral Dissertation). Erasmus University Medical Center. Retrieved from http://hdl.handle.net/1765/17804

Chicago Manual of Style (16^th Edition):

Vos, Rik. “Single Microbubble Imaging.” 2010. Doctoral Dissertation, Erasmus University Medical Center. Accessed October 19, 2019. http://hdl.handle.net/1765/17804.

MLA Handbook (7^th Edition):

Vos, Rik. “Single Microbubble Imaging.” 2010. Web. 19 Oct 2019.

Vancouver:

Vos R. Single Microbubble Imaging. [Internet] [Doctoral dissertation]. Erasmus University Medical Center; 2010. [cited 2019 Oct 19]. Available from: http://hdl.handle.net/1765/17804.

Council of Science Editors:

Vos R. Single Microbubble Imaging. [Doctoral Dissertation]. Erasmus University Medical Center; 2010. Available from: http://hdl.handle.net/1765/17804

Queen Mary, University of London

18. Kelly, Stephen Gerard. Ultrasound imaging of synovitis : relationship to pathobiology and response to therapy.

Degree: PhD, 2014, Queen Mary, University of London

URL: http://qmro.qmul.ac.uk/xmlui/handle/123456789/9010 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.667367

► Ultrasound (US) imaging has made significant progress over the past 20 years in relation to its role in inflammatory arthritis, and in particular, Rheumatoid Arthritis.… (more)

▼ Ultrasound (US) imaging has made significant progress over the past 20 years in relation to its role in inflammatory arthritis, and in particular, Rheumatoid Arthritis. Modern US machines provide crisp, detailed images of superficial anatomical structures which has facilitated the uptake of US imaging as an important assessment tool within the Rheumatology department. Diagnostic and prognostic information can now assist clinicians decisions with the goal of improving patient treatment and subsequent outcome. In addition, 3D US imaging has recently been suggested as an additional imaging modality with potential benefits in the assessment of in?ammatory arthritis. Recent work has focused on providing a reliable, responsive US joint count which can be assimilated into routine care as well as providing a platform for clinical research. Thus, my first aim was to show that a defined limited US data set, including 2D and 3D imaging, shows acceptable reliability. I demonstrate that both imaging modalities are reliable in terms of reading and image acquisition when restricted to a limited US data set. My second aim, was to demonstrate that a limited US data set is responsive. Using both a physiological and pharmacological trigger, I demonstrate that both 2D and 3D imaging are responsive and that combining US endpoints with DAS28 (Disease Activity Score - 28) increased the effect size and identifies treatment effects early. Despite notable advances in musculoskeletal US research, there is still need for better understanding of the pathophysiological correlates of ultrasound imaging. Therefore my final aim was to examine the relationship of Power Doppler Signal (PDS) and gray-scale synovial thickening with histological features of synovitis at a single joint level and with an extended joint US data set. I Firstly show that the harvesting of synovial tissue, using a minimally invasive US-guided biopsy technique, is safe and well tolerated by patients and that the quality of tissue and RNA extracted is good. Using this tissue collection method, I demonstrate a good correlation of US and histological parameters of synovitis (specifically CD68+ sub-lining macrophages) at a single joint level, in both an early and established RA cohort. This relationship is maintained if the US assessment is extended to a discrete US joint data set. Furthermore, within the knee joint I demonstrated that PDS correlates well with synovial tissue expression of inflammatory mediators of neoangiogenesis and histological assessment of synovial vascular area.

Subjects/Keywords: 616.7; Medicine; Ultrasound imaging; Rheumatoid arthritis; Rheumatology

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APA (6^th Edition):

Kelly, S. G. (2014). Ultrasound imaging of synovitis : relationship to pathobiology and response to therapy. (Doctoral Dissertation). Queen Mary, University of London. Retrieved from http://qmro.qmul.ac.uk/xmlui/handle/123456789/9010 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.667367

Chicago Manual of Style (16^th Edition):

Kelly, Stephen Gerard. “Ultrasound imaging of synovitis : relationship to pathobiology and response to therapy.” 2014. Doctoral Dissertation, Queen Mary, University of London. Accessed October 19, 2019. http://qmro.qmul.ac.uk/xmlui/handle/123456789/9010 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.667367.

MLA Handbook (7^th Edition):

Kelly, Stephen Gerard. “Ultrasound imaging of synovitis : relationship to pathobiology and response to therapy.” 2014. Web. 19 Oct 2019.

Vancouver:

Kelly SG. Ultrasound imaging of synovitis : relationship to pathobiology and response to therapy. [Internet] [Doctoral dissertation]. Queen Mary, University of London; 2014. [cited 2019 Oct 19]. Available from: http://qmro.qmul.ac.uk/xmlui/handle/123456789/9010 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.667367.

Council of Science Editors:

Kelly SG. Ultrasound imaging of synovitis : relationship to pathobiology and response to therapy. [Doctoral Dissertation]. Queen Mary, University of London; 2014. Available from: http://qmro.qmul.ac.uk/xmlui/handle/123456789/9010 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.667367

19. Ouellette, Andrew. Analysis of the Effect of Thermal Gradients on the Real-time 2D Imaging of the Spot Weld Process.

Degree: MS, Physics, 2015, University of Windsor

URL: https://scholar.uwindsor.ca/etd/5317

► Many monitoring processes have been proposed for the spot weld process, but most of these techniques involve the use of post weld verification methods.… (more)

Subjects/Keywords: Acoustic; Gradients; Imaging; Modelling; Ultrasound; Weld

11 more images…

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APA (6^th Edition):

Ouellette, A. (2015). Analysis of the Effect of Thermal Gradients on the Real-time 2D Imaging of the Spot Weld Process. (Masters Thesis). University of Windsor. Retrieved from https://scholar.uwindsor.ca/etd/5317

Chicago Manual of Style (16^th Edition):

Ouellette, Andrew. “Analysis of the Effect of Thermal Gradients on the Real-time 2D Imaging of the Spot Weld Process.” 2015. Masters Thesis, University of Windsor. Accessed October 19, 2019. https://scholar.uwindsor.ca/etd/5317.

MLA Handbook (7^th Edition):

Ouellette, Andrew. “Analysis of the Effect of Thermal Gradients on the Real-time 2D Imaging of the Spot Weld Process.” 2015. Web. 19 Oct 2019.

Vancouver:

Ouellette A. Analysis of the Effect of Thermal Gradients on the Real-time 2D Imaging of the Spot Weld Process. [Internet] [Masters thesis]. University of Windsor; 2015. [cited 2019 Oct 19]. Available from: https://scholar.uwindsor.ca/etd/5317.

Council of Science Editors:

Ouellette A. Analysis of the Effect of Thermal Gradients on the Real-time 2D Imaging of the Spot Weld Process. [Masters Thesis]. University of Windsor; 2015. Available from: https://scholar.uwindsor.ca/etd/5317

20. Smith, Brendon. Effects of nutrition and ultrasound imaging on the cardiovascular system.

Degree: PhD, 0191, 2015, University of Illinois – Urbana-Champaign

URL: http://hdl.handle.net/2142/72961

► The work described in this dissertation is focused on two major areas: the biological effects of ultrasound and ultrasound contrast agents, and nutritional interventions to… (more)

▼ The work described in this dissertation is focused on two major areas: the biological effects of ultrasound and ultrasound contrast agents, and nutritional interventions to inhibit the development of atherosclerosis. Ultrasound is a highly flexible and affordable imaging modality that has proven clinically useful in many diagnostic situations ranging from pregnancy to cardiovascular disease and cancer. Ultrasound imaging can be performed with concomitant intravenous administration of microbubble contrast agents to improve image clarity. While useful for imaging of the cardiovascular system, concerns have been raised regarding the safety of ultrasound contrast agents, and further research is needed to determine their biological effects. This work investigates interactions between ultrasound, microbubbles, and the vascular endothelium, the inner cellular lining of blood vessels. The goal of this research is to help define the specific conditions under which contrast ultrasound is safe so that this knowledge can be applied to clinical patient care and diagnosis. A series of four studies were conducted to evaluate the effects of ultrasound and ultrasound contrast agents (Chapters 3-6). First, ultrasound imaging was performed on rabbit arteries, and histological and biochemical analyses were used to determine any effects on the tissue being imaged. As part of this project, an assay was developed and validated for measurement of one of the biomarkers, von Willebrand Factor (Chapter 2). Effects of contrast ultrasound on von Willebrand Factor and atheroma thickness were observed. Next, another rabbit study was performed to assess the effect of contrast ultrasound on Hsp70, a cellular stress protein. The ultrasound procedure was hypothesized to elevate Hsp70 protein levels. Hsp70 protein levels were measured in aorta tissue at the site of ultrasound exposure by Western blot. Ultrasound with contrast agent did not affect Hsp70 levels (Chapter 4). In addition to rabbits, work with ApoE-/- mice and rats will be described. We did not observe any adverse effects of ultrasound in these models (Chapters 5 and 6). We also studied the effects of tomato and soy germ on atherosclerosis in ApoE-/- mice (Chapter 7). We did not find that tomato and soy germ decreased atherosclerosis, but soy germ consumption favorably affected plasma and tissue lipid accumulation. Advisors/Committee Members: O'Brien, William, Jr. (advisor), Erdman, John, Jr. (advisor), Johnson, Rodney W. (Committee Chair), O'Brien, William, Jr. (committee member), Erdman Jr., John (committee member), Wilund, Kenneth R. (committee member).

Subjects/Keywords: Atherosclerosis; Ultrasound; Imaging; Nutrition; Tomatoes; Soy

12 more images…

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APA (6^th Edition):

Smith, B. (2015). Effects of nutrition and ultrasound imaging on the cardiovascular system. (Doctoral Dissertation). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/72961

Chicago Manual of Style (16^th Edition):

Smith, Brendon. “Effects of nutrition and ultrasound imaging on the cardiovascular system.” 2015. Doctoral Dissertation, University of Illinois – Urbana-Champaign. Accessed October 19, 2019. http://hdl.handle.net/2142/72961.

MLA Handbook (7^th Edition):

Smith, Brendon. “Effects of nutrition and ultrasound imaging on the cardiovascular system.” 2015. Web. 19 Oct 2019.

Vancouver:

Smith B. Effects of nutrition and ultrasound imaging on the cardiovascular system. [Internet] [Doctoral dissertation]. University of Illinois – Urbana-Champaign; 2015. [cited 2019 Oct 19]. Available from: http://hdl.handle.net/2142/72961.

Council of Science Editors:

Smith B. Effects of nutrition and ultrasound imaging on the cardiovascular system. [Doctoral Dissertation]. University of Illinois – Urbana-Champaign; 2015. Available from: http://hdl.handle.net/2142/72961

University of Southern California

21. Zheng, Fan. High frequency ultrasonic phased array system and its applications.

Degree: PhD, Biomedical Engineering, 2012, University of Southern California

URL: http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll3/id/109547/rec/3165

► While similar to a linear-switched array in structure, an ultrasound linear phased array (simply called phased array) is quite different in operation. It is capable… (more)

▼ While similar to a linear-switched array in structure, an ultrasound linear phased array (simply called phased array) is quite different in operation. It is capable of beam steering to form fan-shaped sector images without inducing grating lobes. Moreover, the relative smaller array footprint is useful where only very limited contact surface is permitted. High frequency phased arrays combine the advantages of the phased array and high frequency ultrasound, which offer both small footprint and high spatial resolution. This dissertation reports the design and development of a digital ultrasonic imaging platform with raw RF data acquisition capability, which can be paired with a prototype 64-element 26 MHz phased array transducer. A wire phantom image showed that -6 dB lateral and axial resolutions were 209 and 104 μm, respectively, which were in good agreement with the Field II simulation. Anechoic cyst tissue-mimicking phantom images demonstrated its capability to detect cysts of 300 μm in diameter. An image of a rabbit eyeball in vitro was also acquired. This imaging platform is designed for the purpose of testing high frequency phased arrays under development as well as facilitating the development in novel array signal processing algorithms. ❧ Without additional change in the system hardware, the current high frequency array system can be also applied in the industrial non-destructive testing (NDT) applications. A motorized XY stage allows the array system to acquire C-mode scan as well as normal B-mode scan with bigger scanning area. Electronic scanning in array system could dramatically reduce the total scanning time compare to single element system. An aluminum sample and a silicon carbide sample were examined to test the system in non-destructive testing. ❧ Besides the applications in biomedical imaging and non-destructive testing, the high frequency ultrasonic phased array and system are shown to be capable of trapping and translating microparticles precisely and efficiently, made possible due to the fact that the acoustic beam produced by a phased array can be both focused and steered. Acoustic manipulation of microparticles by a phased array is advantageous over a single element transducer since there is no mechanical movement required for the array. Experimental results show that 45 μm diameter polystyrene microspheres can be easily and accurately trapped and moved to desired positions by a 64-element 26 MHz phased array. Advisors/Committee Members: Shung, Kirk Koping (Committee Chair), Yen, Jesse T. (Committee Member), Kim, Eun Sok (Committee Member), Zhou, Qifa (Committee Member).

Subjects/Keywords: high frequency; ultrasound; phased array; imaging system

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APA (6^th Edition):

Zheng, F. (2012). High frequency ultrasonic phased array system and its applications. (Doctoral Dissertation). University of Southern California. Retrieved from http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll3/id/109547/rec/3165

Chicago Manual of Style (16^th Edition):

Zheng, Fan. “High frequency ultrasonic phased array system and its applications.” 2012. Doctoral Dissertation, University of Southern California. Accessed October 19, 2019. http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll3/id/109547/rec/3165.

MLA Handbook (7^th Edition):

Zheng, Fan. “High frequency ultrasonic phased array system and its applications.” 2012. Web. 19 Oct 2019.

Vancouver:

Zheng F. High frequency ultrasonic phased array system and its applications. [Internet] [Doctoral dissertation]. University of Southern California; 2012. [cited 2019 Oct 19]. Available from: http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll3/id/109547/rec/3165.

Council of Science Editors:

Zheng F. High frequency ultrasonic phased array system and its applications. [Doctoral Dissertation]. University of Southern California; 2012. Available from: http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll3/id/109547/rec/3165

University of Toronto

22. Aly, Al-Hassan. Ultrasound Imaging of Bone for Spinal Fusion Surgery Guidance: Simulation and Experimental Results.

Degree: 2010, University of Toronto

URL: http://hdl.handle.net/1807/24233

►

In order to continue development of an ultrasound-guidance system for spinal fusion surgery, simulation and experimental research was conducted to study the effects of bone… (more)

Subjects/Keywords: ultrasound; imaging; bone; spinal fusion; 0541

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APA (6^th Edition):

Aly, A. (2010). Ultrasound Imaging of Bone for Spinal Fusion Surgery Guidance: Simulation and Experimental Results. (Masters Thesis). University of Toronto. Retrieved from http://hdl.handle.net/1807/24233

Chicago Manual of Style (16^th Edition):

Aly, Al-Hassan. “Ultrasound Imaging of Bone for Spinal Fusion Surgery Guidance: Simulation and Experimental Results.” 2010. Masters Thesis, University of Toronto. Accessed October 19, 2019. http://hdl.handle.net/1807/24233.

MLA Handbook (7^th Edition):

Aly, Al-Hassan. “Ultrasound Imaging of Bone for Spinal Fusion Surgery Guidance: Simulation and Experimental Results.” 2010. Web. 19 Oct 2019.

Vancouver:

Aly A. Ultrasound Imaging of Bone for Spinal Fusion Surgery Guidance: Simulation and Experimental Results. [Internet] [Masters thesis]. University of Toronto; 2010. [cited 2019 Oct 19]. Available from: http://hdl.handle.net/1807/24233.

Council of Science Editors:

Aly A. Ultrasound Imaging of Bone for Spinal Fusion Surgery Guidance: Simulation and Experimental Results. [Masters Thesis]. University of Toronto; 2010. Available from: http://hdl.handle.net/1807/24233

San Jose State University

23. Pourfathi, Mehrdad. Ultrasound Strain Imaging Using Sector Arrays For Monitoring Prostate Ablation Therapy.

Degree: MS, Electrical Engineering, 2011, San Jose State University

URL: https://doi.org/10.31979/etd.dvcc-7uuv ; https://scholarworks.sjsu.edu/etd_theses/4071

► Thermal ablation treatment is a relatively new method for prostate cancer therapy, where high energy focused ultrasound is used to thermally coagulate cancerous tissue.… (more)

Subjects/Keywords: Elastography; Hyperthermia; Prostate Cancer; Strain Imaging; Ultrasound

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APA (6^th Edition):

Pourfathi, M. (2011). Ultrasound Strain Imaging Using Sector Arrays For Monitoring Prostate Ablation Therapy. (Masters Thesis). San Jose State University. Retrieved from https://doi.org/10.31979/etd.dvcc-7uuv ; https://scholarworks.sjsu.edu/etd_theses/4071

Chicago Manual of Style (16^th Edition):

Pourfathi, Mehrdad. “Ultrasound Strain Imaging Using Sector Arrays For Monitoring Prostate Ablation Therapy.” 2011. Masters Thesis, San Jose State University. Accessed October 19, 2019. https://doi.org/10.31979/etd.dvcc-7uuv ; https://scholarworks.sjsu.edu/etd_theses/4071.

MLA Handbook (7^th Edition):

Pourfathi, Mehrdad. “Ultrasound Strain Imaging Using Sector Arrays For Monitoring Prostate Ablation Therapy.” 2011. Web. 19 Oct 2019.

Vancouver:

Pourfathi M. Ultrasound Strain Imaging Using Sector Arrays For Monitoring Prostate Ablation Therapy. [Internet] [Masters thesis]. San Jose State University; 2011. [cited 2019 Oct 19]. Available from: https://doi.org/10.31979/etd.dvcc-7uuv ; https://scholarworks.sjsu.edu/etd_theses/4071.

Council of Science Editors:

Pourfathi M. Ultrasound Strain Imaging Using Sector Arrays For Monitoring Prostate Ablation Therapy. [Masters Thesis]. San Jose State University; 2011. Available from: https://doi.org/10.31979/etd.dvcc-7uuv ; https://scholarworks.sjsu.edu/etd_theses/4071

University of Sydney

24. Lau, Siu Fong Louisa. Precision Imaging Ultrasound Technology - Does It Improve Accuracy And Increase Confidence In Diagnosing Breast Tumours? .

Degree: 2015, University of Sydney

URL: http://hdl.handle.net/2123/13931

► Objective To determine the effect of Precision Imaging (PI), an innovative speckle reduction algorithm, on the diagnostic efficacy in breast ultrasound Material and methods Patients… (more)

Subjects/Keywords: breast ultrasound; speckle reduction; Precision Imaging

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APA (6^th Edition):

Lau, S. F. L. (2015). Precision Imaging Ultrasound Technology - Does It Improve Accuracy And Increase Confidence In Diagnosing Breast Tumours? . (Thesis). University of Sydney. Retrieved from http://hdl.handle.net/2123/13931

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Lau, Siu Fong Louisa. “Precision Imaging Ultrasound Technology - Does It Improve Accuracy And Increase Confidence In Diagnosing Breast Tumours? .” 2015. Thesis, University of Sydney. Accessed October 19, 2019. http://hdl.handle.net/2123/13931.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Lau, Siu Fong Louisa. “Precision Imaging Ultrasound Technology - Does It Improve Accuracy And Increase Confidence In Diagnosing Breast Tumours? .” 2015. Web. 19 Oct 2019.

Vancouver:

Lau SFL. Precision Imaging Ultrasound Technology - Does It Improve Accuracy And Increase Confidence In Diagnosing Breast Tumours? . [Internet] [Thesis]. University of Sydney; 2015. [cited 2019 Oct 19]. Available from: http://hdl.handle.net/2123/13931.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Lau SFL. Precision Imaging Ultrasound Technology - Does It Improve Accuracy And Increase Confidence In Diagnosing Breast Tumours? . [Thesis]. University of Sydney; 2015. Available from: http://hdl.handle.net/2123/13931

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Arizona

25. Sung, Jae-Hyun. A Cross-linguistic Articulatory Analysis of Palatalization in Korean, English, and Scottish Gaelic .

Degree: 2015, University of Arizona

URL: http://hdl.handle.net/10150/604864

► Palatalization refers to a type of coarticulation in which the place of articulation of some sound is closer to the palate than otherwise expected, very… (more)

Subjects/Keywords: palatalization; speech production; ultrasound imaging; Linguistics; articulation

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APA (6^th Edition):

Sung, J. (2015). A Cross-linguistic Articulatory Analysis of Palatalization in Korean, English, and Scottish Gaelic . (Doctoral Dissertation). University of Arizona. Retrieved from http://hdl.handle.net/10150/604864

Chicago Manual of Style (16^th Edition):

Sung, Jae-Hyun. “A Cross-linguistic Articulatory Analysis of Palatalization in Korean, English, and Scottish Gaelic .” 2015. Doctoral Dissertation, University of Arizona. Accessed October 19, 2019. http://hdl.handle.net/10150/604864.

MLA Handbook (7^th Edition):

Sung, Jae-Hyun. “A Cross-linguistic Articulatory Analysis of Palatalization in Korean, English, and Scottish Gaelic .” 2015. Web. 19 Oct 2019.

Vancouver:

Sung J. A Cross-linguistic Articulatory Analysis of Palatalization in Korean, English, and Scottish Gaelic . [Internet] [Doctoral dissertation]. University of Arizona; 2015. [cited 2019 Oct 19]. Available from: http://hdl.handle.net/10150/604864.

Council of Science Editors:

Sung J. A Cross-linguistic Articulatory Analysis of Palatalization in Korean, English, and Scottish Gaelic . [Doctoral Dissertation]. University of Arizona; 2015. Available from: http://hdl.handle.net/10150/604864

26. Bergel, Antoine. Cerebral vascular patterns associated with theta and gamma rhythms during unrestrained behavior and REM sleep : Réponses hémodynamiques cérébrales associées aux rythmes thêta et gamma lors du mouvement libre et du sommeil paradoxal.

Degree: Docteur es, Sciences de la vie. Neurosciences, 2016, Sorbonne Paris Cité

URL: http://www.theses.fr/2016USPCC239

►

Le rythme thêta est un rythme cérébral associé à l’activité locomotrice et au sommeil paradoxal. Bien que son implication dans la communication entre régions du… (more)

▼

Le rythme thêta est un rythme cérébral associé à l’activité locomotrice et au sommeil paradoxal. Bien que son implication dans la communication entre régions du cerveau et processus mnésiques ait largement été démontrée, il persiste un manque de données extensives dû à la difficulté d’imager l’ensemble de l’activité cérébrale dans des conditions naturelles de locomotion et d’exploration. Dans cette thèse, j’ai développé une approche qui combine l’enregistrement des potentiels de champs locaux à l’imagerie ultrasonore fonctionnelle (fUS) sur l’animal en mouvement libre. Pour la première fois, j’ai pu révéler les réponses hémodynamiques associées au rythme thêta dans la plupart des structures du système nerveux central avec de bonnes résolutions spatiale (100 x 100 x 400 μm) et temporelle (200 ms). Pendant la locomotion et le sommeil, les variations hémodynamiques de l’hippocampe, du thalamus dorsal et du cortex (rétrosplenial, somatosensoriel) corrèlent fortement avec la puissance instantanée du signal thêta hippocampique, avec un décalage temporel variant de 0.7 s à 2.0 s selon les structures. De manière intéressante, les rythmes gamma hippocampiques moyen (55-95 Hz) et rapide (100-150 Hz) expliquent la variance des signaux hémodynamiques mieux que le seul rythme thêta, alors que le rythme gamma lent (30-50 Hz) est non pertinent. L’hyperémie fonctionnelle de l’hippocampe suit séquentiellement la boucle tri-synaptique (gyrus denté - région CA3 - région CA1) et se renforce considérablement à mesure que la tâche progresse. Lors du sommeil paradoxal, j’ai observé une hyperémie tonique globale ainsi que des activations phasiques de grande amplitude initiées dans le thalamus et terminant dans les aires corticales, que nous avons appelées “poussées vasculaires”. De fortes bouffées d’activité gamma rapide (100-150 Hz) précèdent de manière robuste ces poussées vasculaires, l’inverse n’étant pas vrai. Dans l’ensemble, ces résultats révèlent la dynamique spatio-temporelle des signaux hémodynamiques associés à la locomotion et au sommeil paradoxal et suggèrent un lien fort entre rythmes thêta, gamma rapide et activité vasculaire globale

Theta rhythm is a prominent oscillatory pattern of EEG strongly associated with active locomotion and REM sleep. While it has been shown to play a crucial role in communication between brain areas and memory processes, there is a lack of extensive data due to the difficulty to image global brain activity during locomotion behavior. In this thesis, I developed an approach that combines local field potential recordings (LFP) and functional ultrasound imaging (fUS) to unrestrained rats. For the first time, I could image the hemodynamic responses associated with theta rhythm in most central nervous system (CNS) structures, with high spatial (100 x 100 x 400 μm) and temporal (200 ms) resolutions. During running and REM sleep, hemodynamic variations in the hippocampus, dorsal thalamus and cortices (S1BF, retrosplenial) correlated strongly with instantaneous theta power, with a delay ranging from 0.7…

Advisors/Committee Members: Cauli, Bruno (thesis director), Cohen, Ivan (thesis director).

Subjects/Keywords: Imagerie Ultrasonore Fonctionnelle; Functional Ultrasound Imaging

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APA (6^th Edition):

Bergel, A. (2016). Cerebral vascular patterns associated with theta and gamma rhythms during unrestrained behavior and REM sleep : Réponses hémodynamiques cérébrales associées aux rythmes thêta et gamma lors du mouvement libre et du sommeil paradoxal. (Doctoral Dissertation). Sorbonne Paris Cité. Retrieved from http://www.theses.fr/2016USPCC239

Chicago Manual of Style (16^th Edition):

Bergel, Antoine. “Cerebral vascular patterns associated with theta and gamma rhythms during unrestrained behavior and REM sleep : Réponses hémodynamiques cérébrales associées aux rythmes thêta et gamma lors du mouvement libre et du sommeil paradoxal.” 2016. Doctoral Dissertation, Sorbonne Paris Cité. Accessed October 19, 2019. http://www.theses.fr/2016USPCC239.

MLA Handbook (7^th Edition):

Bergel, Antoine. “Cerebral vascular patterns associated with theta and gamma rhythms during unrestrained behavior and REM sleep : Réponses hémodynamiques cérébrales associées aux rythmes thêta et gamma lors du mouvement libre et du sommeil paradoxal.” 2016. Web. 19 Oct 2019.

Vancouver:

Bergel A. Cerebral vascular patterns associated with theta and gamma rhythms during unrestrained behavior and REM sleep : Réponses hémodynamiques cérébrales associées aux rythmes thêta et gamma lors du mouvement libre et du sommeil paradoxal. [Internet] [Doctoral dissertation]. Sorbonne Paris Cité; 2016. [cited 2019 Oct 19]. Available from: http://www.theses.fr/2016USPCC239.

Council of Science Editors:

Bergel A. Cerebral vascular patterns associated with theta and gamma rhythms during unrestrained behavior and REM sleep : Réponses hémodynamiques cérébrales associées aux rythmes thêta et gamma lors du mouvement libre et du sommeil paradoxal. [Doctoral Dissertation]. Sorbonne Paris Cité; 2016. Available from: http://www.theses.fr/2016USPCC239

27. Li, Wenguang. Image and Signal Processing in Intravascular Ultrasound.

Degree: Department of Cardiology, 1997, Erasmus University Medical Center

URL: http://hdl.handle.net/1765/18187

► textabstractIntravascular ultrasound (rvUS) is a new imaging mOdality providing real-time, crosssectional, high-resolution images of the arterial lumen and vessel wall. In contrast to conventional x-ray… (more)

▼ textabstractIntravascular ultrasound (rvUS) is a new imaging mOdality providing real-time, crosssectional, high-resolution images of the arterial lumen and vessel wall. In contrast to conventional x-ray angiography that only displays silhouette views of the vessel lumen, IVUS imaging permits visualization of lesion morphology and accurate measurements of arterial cross-sectional dimensions in patients. These unique capabilities have led to many important clinical applications including quantitative assessment of the severity, restenosis, progression of atherosclerosis, selection and guidance of catheterbased therapeutic procedures and short- and long-term evaluation of the outcome of an intravascular intervention. Like the progress of other medial imaging modalities, the advent of IVUS techniques has brought in new challenges in the field of signal and image processing. Quantitative analysis of IVUS images requires the identification of arterial structures such as the lumen and plaque within an image. Manual contour tracing is well known to be time consuming and subjective. Development of an automated contour detection method may improve the reproducibility of quantitative IVUS and avoid a tedious manual procedure. Computerized three-dimensional (3D) reconstruction of an IVUS image series may extend the tomographic data to a more powerful volumetric assessment of the vessel segment. Obviously, this could not be achieved without the advance of 3D image processing techniques. Furthermore, it is demonstrated that processing of the original radio frequency (RF) echo signals provides an efficient means to improve the IVUS image quality as well as a new approach to extract volumetric flow information. The goals of the studies reported in this thesis are therefore directed toward development of video image and RF signal processing techniques for image enhancement, automated contour detection, 3D reconstruction and flow imaging. In this chapter several IVUS scanning mechanisms and some background information about ultrasonic imaging are briefly introduced. The principles of different video-based contour detection approaches and examples of contour detection in echocardiograms are discussed. Subsequently, applications of RF analysis in IVUS images are reviewed, followed by the scope of this thesis in the final part.

Subjects/Keywords: imaging; intravasular ultrasound

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APA (6^th Edition):

Li, W. (1997). Image and Signal Processing in Intravascular Ultrasound. (Doctoral Dissertation). Erasmus University Medical Center. Retrieved from http://hdl.handle.net/1765/18187

Chicago Manual of Style (16^th Edition):

Li, Wenguang. “Image and Signal Processing in Intravascular Ultrasound.” 1997. Doctoral Dissertation, Erasmus University Medical Center. Accessed October 19, 2019. http://hdl.handle.net/1765/18187.

MLA Handbook (7^th Edition):

Li, Wenguang. “Image and Signal Processing in Intravascular Ultrasound.” 1997. Web. 19 Oct 2019.

Vancouver:

Li W. Image and Signal Processing in Intravascular Ultrasound. [Internet] [Doctoral dissertation]. Erasmus University Medical Center; 1997. [cited 2019 Oct 19]. Available from: http://hdl.handle.net/1765/18187.

Council of Science Editors:

Li W. Image and Signal Processing in Intravascular Ultrasound. [Doctoral Dissertation]. Erasmus University Medical Center; 1997. Available from: http://hdl.handle.net/1765/18187

Duke University

28. Li, You. Coherent flow power Doppler imaging .

Degree: 2017, Duke University

URL: http://hdl.handle.net/10161/16377

► Ultrasonic flow detection is a widely used technique to detect vessel, measure blood flow velocities, and monitor perfusion. Conventional techniques include color Doppler imaging… (more)

Subjects/Keywords: Medical imaging; Acoustics; Medicine; coherence; Doppler; Ultrasound

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APA (6^th Edition):

Li, Y. (2017). Coherent flow power Doppler imaging . (Thesis). Duke University. Retrieved from http://hdl.handle.net/10161/16377

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Li, You. “Coherent flow power Doppler imaging .” 2017. Thesis, Duke University. Accessed October 19, 2019. http://hdl.handle.net/10161/16377.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Li, You. “Coherent flow power Doppler imaging .” 2017. Web. 19 Oct 2019.

Vancouver:

Li Y. Coherent flow power Doppler imaging . [Internet] [Thesis]. Duke University; 2017. [cited 2019 Oct 19]. Available from: http://hdl.handle.net/10161/16377.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Li Y. Coherent flow power Doppler imaging . [Thesis]. Duke University; 2017. Available from: http://hdl.handle.net/10161/16377

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Southern California

29. Chabok, Hamid Reza. Development of high frequency composites for ultrasound transducer applications.

Degree: PhD, Industrial and Systems Engineering, 2012, University of Southern California

URL: http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll3/id/213490/rec/1938

► Conventional ultrasound imaging transducers operating in the 2-16 MHz range have a large footprint and inadequate spatial resolution to resolve fine structures in humans and… (more)

▼ Conventional ultrasound imaging transducers operating in the 2-16 MHz range have a large footprint and inadequate spatial resolution to resolve fine structures in humans and small animals. Therefore, this research is intended to enhance the design and fabrication of high frequency (HF) composite annular arrays to allow for non-invasive, high-resolution imaging of small biological structures. The annular array transducer is a viable alternative to linear and phased arrays because of the capability of dynamic focusing, low electronic channel count, and more affordable fabrication cost. In this work, the design, fabrication, and testing of HF 1-3 composite annular array transducers are presented. ❧ We have developed an annular array using a piezoelectric ceramic with moderately high dielectric permittivity and electro-mechanical coupling coefficient. The design is optimized via computer simulation. Then the annular array is fabricated with the 1-3 composite of ultra fine ceramic posts of 19 μm wide separated by a 6 μm polymer kerf, and an unloaded epoxy backing layer. Eight annuli electrodes are printed on a custom-designed double-sided flexible circuit to connect the composite annuli with 75 Ohm coaxial cables. Finally, an electroplated epoxy matching layer is used as the ground side to enhance the pulse-echo response of the array. Investigation has also begun into a novel solid free form (SFF) fabrication approach using intense light projection. The overarching aim is the development of piezomaterials and composites quickly and inexpensively. ❧ During the array fabrication process a simple and novel method were established to remove the chrome-gold electrode from polymer portions of the 1-3 composite without removing the electroplating over the ceramic posts. Therefore the fabrication process was greatly simplified since photolithography or laser ablation was not needed for electrode patterning. Also because all posts have independent electrodes, the alignment between the composite and flex circuit was not critical to the success of the fabrication process. ❧ The manufactured annular array is a flat-aperture composite 8-element array transducer. The prototype array was tested and results were in a good agreement with those predicted by a circuit-analogous (KLM) model. The average center frequency estimated from the measured pulse-echo responses of array elements was 33.5 MHz and the -6 dB fractional bandwidth was 57 %. The minimum insertion loss recorded was 12.52 dB, and the maximum crosstalk between the nearest neighbor elements was less than -37 dB. Images of a wire phantom and excised porcine eye were obtained to show the capabilities of the array for high frequency ultrasound imaging. ❧ In the process of developing the 1-3 composites, a new technology capable of fabricating piezoelectric composites, and 2D annular ultrasonic arrays with complex geometry was evaluated and studied. Conventional methods for fabricating ultrasound imaging transducers especially for high frequency (>20 MHz) range are expensive, time… Advisors/Committee Members: Wu, Shinyi (Committee Chair), Shung, Kirk Koping (Committee Member), Chen, Yong (Committee Member), Wang, Pin (Committee Member).

Subjects/Keywords: high frequency ultrasound transducer; medical ultrasound imaging; piezocomposite

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Chabok, H. R. (2012). Development of high frequency composites for ultrasound transducer applications. (Doctoral Dissertation). University of Southern California. Retrieved from http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll3/id/213490/rec/1938

Chicago Manual of Style (16^th Edition):

Chabok, Hamid Reza. “Development of high frequency composites for ultrasound transducer applications.” 2012. Doctoral Dissertation, University of Southern California. Accessed October 19, 2019. http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll3/id/213490/rec/1938.

MLA Handbook (7^th Edition):

Chabok, Hamid Reza. “Development of high frequency composites for ultrasound transducer applications.” 2012. Web. 19 Oct 2019.

Vancouver:

Chabok HR. Development of high frequency composites for ultrasound transducer applications. [Internet] [Doctoral dissertation]. University of Southern California; 2012. [cited 2019 Oct 19]. Available from: http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll3/id/213490/rec/1938.

Council of Science Editors:

Chabok HR. Development of high frequency composites for ultrasound transducer applications. [Doctoral Dissertation]. University of Southern California; 2012. Available from: http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll3/id/213490/rec/1938

University of Illinois – Urbana-Champaign

30. Reeg, Jonathan R. Null subtraction imaging technique for biomedical ultrasound imaging.

Degree: MS, Electrical & Computer Engr, 2016, University of Illinois – Urbana-Champaign

URL: http://hdl.handle.net/2142/90529

► In ultrasonic imaging, reduction of lateral sidelobes results in an improved image with less distortion and fewer artifacts. In general, apodization is used to lower… (more)

▼ In ultrasonic imaging, reduction of lateral sidelobes results in an improved image with less distortion and fewer artifacts. In general, apodization is used to lower sidelobes in exchange for increasing the width of the mainlobe and thus decreasing lateral resolution. Null subtraction imaging (NSI) is a nonlinear image processing technique that uses different on-receive apodizations on copies of the same image to reduce sidelobe levels while also dramatically improving lateral resolution. In the NSI technique, three apodization functions are applied on receive. The images created with the different weighting schemes are then added to form a new image with improved sidelobe performance and better lateral resolution compared to conventional apodization. To evaluate the performance of this technique, experimental tasks were performed with an ATS539 phantom containing wire targets to assess lateral resolution and cylindrical anechoic and hyperechoic targets to assess contrast. A 9L4 array was used in the measurements connected to an Ultrasonix RP system with a SonixDAQ. Image reconstruction involved using delay and sum beamforming with apodization. Images were constructed using NSI and compared with a rectangular weighted aperture. In experiments, the lateral resolution was observed to improve by a factor of up to 25 times when compared to rectangular apodization. Image quality was assessed by estimation of lateral resolution (-6-dB receive beamwidth), the mainlobe to sidelobe ratio (MSR) in dB and estimation of the contrast-to-noise ratio (CNR). At f/# = 2 focusing with NSI, the -6-dB beamwidth on receive as measured from a small wire target in the ATS phantom was 0.12lambda. Sidelobes were observed to decrease at each f/# by an average of 29 dB with NSI compared to rectangular apodization. However, the ability to observe the contrast of hyperechoic and anechoic targets was lost when utilizing the NSI scheme, decreasing from -2.13 dB to -0.71 dB for an anechoic target. This could be mitigated by compounding NSI with the B-mode image. Advisors/Committee Members: Oelze, Michael L (advisor).

Subjects/Keywords: ultrasound; beamforming; delay and sum; ultrasound imaging; superresolution; apodization

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Reeg, J. R. (2016). Null subtraction imaging technique for biomedical ultrasound imaging. (Thesis). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/90529

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Reeg, Jonathan R. “Null subtraction imaging technique for biomedical ultrasound imaging.” 2016. Thesis, University of Illinois – Urbana-Champaign. Accessed October 19, 2019. http://hdl.handle.net/2142/90529.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Reeg, Jonathan R. “Null subtraction imaging technique for biomedical ultrasound imaging.” 2016. Web. 19 Oct 2019.

Vancouver:

Reeg JR. Null subtraction imaging technique for biomedical ultrasound imaging. [Internet] [Thesis]. University of Illinois – Urbana-Champaign; 2016. [cited 2019 Oct 19]. Available from: http://hdl.handle.net/2142/90529.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Reeg JR. Null subtraction imaging technique for biomedical ultrasound imaging. [Thesis]. University of Illinois – Urbana-Champaign; 2016. Available from: http://hdl.handle.net/2142/90529

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Open Access Theses and Dissertations