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Universidade Estadual de Campinas

1. Amorim, João Paulo de Arruda, 1981-. Caracterização do comportamento materno e suas implicações no desenvovimento fisico,na função reprodutiva e no perfil hormonal da prole feminina de ratas UChA e UChB (consumidoras voluntárias de etanol a 10%): Maternal care evaluation and effecta of the physical development, reproductive functions and hormonal profile of UChA UChB rats female offspring (10% v/v ethanol voluntary intake).

Degree: 2012, Universidade Estadual de Campinas

Abstract: Studies focused on drug-dependent mothers (mainly ethanol-dependent mothers) have demonstrated that there is an enormous difference in the care of their children compared to non-dependent mothers, showing an disorder in maternal behavior during the postnatal period, which corresponds to the period where the first social bonds are formed and the animal's organism is very sensible to the effects of environmental stimuli. Various studies have documented the consequences of ethanol use during pregnancy for the health of the infant, but little attention has been given to the mother-child relationship in alcoholic female during the postnatal period and the consequences of this relationship to female offspring in adulthood. The aim of the present work is to evaluate maternal care in ethanol-preferring rats (UChA and UChB) and its effects on physical development, in sexual function and in status hormones in female offspring. The behavior was evaluated by observing the following parameters: carry, licking/grooming, arched-back nursing and licking/grooming, arched-back nursing, passive nursing, contact and not with the pups. The evaluation of the physical development of the female offspring considered the day of birth of hair, eye opening and detached ears. To evaluate the early sexual development were analyzed days of vaginal opening and age of first and second estrous. The reproductive function was evaluated by the regularity of the estrous cycle, the expression of receptors AR, ER-? and ER-? in the ovary and the hormonal status of female offspring (plasma levels of FSH, LH, 17?-estradiol, progesterone and corticosterone). UChA mothers showed higher frequencies of carrying, licking/grooming and nursing the pups. Mothers high care evidencing the highest plasma corticosterone levels and 17?-estradiol. The UChA offspring showed greater body weight gain, accelerated eye opening, vaginal opening, the installation and synchronization of estrous cycle. The female offspring who received low maternal care (UChB) showed an increase of the estrous cycle, concentrations of corticosterone and 17?-estradiol and ovarian receptors (ER-? and ER-?, higher ovarian weight and increased number of primordial, antral and mature follicles and higher Immunoreactivity for Ki-67 in the ovarian follicles. We conclude that UChB rats show marked variations in maternal care, being classified as low maternal care and the variation of maternal care directly affects the physical, the installation of puberty, hormone levels, deregulate the estrous cycle and folliculogenesis and differentially regulates the expression of receptors ER-? and ER-? in the ovaries of adult rats Advisors/Committee Members: UNIVERSIDADE ESTADUAL DE CAMPINAS (CRUESP), Martinez, Francisco Eduardo (advisor), Mello Junior, Wílson de (coadvisor), Universidade Estadual de Campinas. Instituto de Biologia (institution), Programa de Pós-Graduação em Biologia Celular e Estrutural (nameofprogram), Segatelli, Tania Mara (committee member), Santos, Fernanda Cristina Alcântara dos (committee member), Fávaro, Wagner José (committee member), Scarano, Wellerson Rodrigo (committee member).

Subjects/Keywords: Comportamento materno; Rato - Desenvolvimento; Reprodução; Hormônios; Rato UChA; Rato UChB; Maternal behavior; Rats - Development; Reproduction; Hormones; UChA rat; UChB rat

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APA (6th Edition):

Amorim, João Paulo de Arruda, 1. (2012). Caracterização do comportamento materno e suas implicações no desenvovimento fisico,na função reprodutiva e no perfil hormonal da prole feminina de ratas UChA e UChB (consumidoras voluntárias de etanol a 10%): Maternal care evaluation and effecta of the physical development, reproductive functions and hormonal profile of UChA UChB rats female offspring (10% v/v ethanol voluntary intake). (Thesis). Universidade Estadual de Campinas. Retrieved from http://repositorio.unicamp.br/jspui/handle/REPOSIP/317536

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Amorim, João Paulo de Arruda, 1981-. “Caracterização do comportamento materno e suas implicações no desenvovimento fisico,na função reprodutiva e no perfil hormonal da prole feminina de ratas UChA e UChB (consumidoras voluntárias de etanol a 10%): Maternal care evaluation and effecta of the physical development, reproductive functions and hormonal profile of UChA UChB rats female offspring (10% v/v ethanol voluntary intake).” 2012. Thesis, Universidade Estadual de Campinas. Accessed October 22, 2020. http://repositorio.unicamp.br/jspui/handle/REPOSIP/317536.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Amorim, João Paulo de Arruda, 1981-. “Caracterização do comportamento materno e suas implicações no desenvovimento fisico,na função reprodutiva e no perfil hormonal da prole feminina de ratas UChA e UChB (consumidoras voluntárias de etanol a 10%): Maternal care evaluation and effecta of the physical development, reproductive functions and hormonal profile of UChA UChB rats female offspring (10% v/v ethanol voluntary intake).” 2012. Web. 22 Oct 2020.

Vancouver:

Amorim, João Paulo de Arruda 1. Caracterização do comportamento materno e suas implicações no desenvovimento fisico,na função reprodutiva e no perfil hormonal da prole feminina de ratas UChA e UChB (consumidoras voluntárias de etanol a 10%): Maternal care evaluation and effecta of the physical development, reproductive functions and hormonal profile of UChA UChB rats female offspring (10% v/v ethanol voluntary intake). [Internet] [Thesis]. Universidade Estadual de Campinas; 2012. [cited 2020 Oct 22]. Available from: http://repositorio.unicamp.br/jspui/handle/REPOSIP/317536.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Amorim, João Paulo de Arruda 1. Caracterização do comportamento materno e suas implicações no desenvovimento fisico,na função reprodutiva e no perfil hormonal da prole feminina de ratas UChA e UChB (consumidoras voluntárias de etanol a 10%): Maternal care evaluation and effecta of the physical development, reproductive functions and hormonal profile of UChA UChB rats female offspring (10% v/v ethanol voluntary intake). [Thesis]. Universidade Estadual de Campinas; 2012. Available from: http://repositorio.unicamp.br/jspui/handle/REPOSIP/317536

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation


Universidade Estadual de Campinas

2. Almeida-Francia, Camila Contin Diniz de. Ciclo estral, histologia e ultra-estrutura do epitelio da tuba uterina da linhagem de ratos UChA e UChB (bebedores voluntarios de etanol): Estrous cycle, histology and ultrastructure of the uterine tube epithelium of UChA and UChB rats lineage (ethanol voluntary consumers).

Degree: 2005, Universidade Estadual de Campinas

Abstract: Alcoholism is the third most serious problem of World Public Health. Although the majority consists of men, the index of women addicted to alcoholic beverages is increasing. The uterine tube promotes the necessary means for maturation of female and male gametes (capacitation), the fertilization and the initial development of the embI)'o. The varieties VChA and VChB constitute rare models for works related to genetic, biochemical, physiological, nutritional, and pharmacological effects of alcohol that are important factors in human alcoholism. Thus the present work analyzed the estrous cycle and the epithelial cells ofthe uterine tube (intramural- In, isthmus - I, ampulla - A, injUndibulum - Infandfimbrias - F) ofthe rat lineage VChA and VChB, voluntary drinkers of alcohol, divided into three groups: 1st) VChA, voluntary consumption of 6.05 gIKglday of ethanollO%; 2nd) VChB, voluntary consumption of8.18 gIKglday of ethanollO% and 3rd) Wistar rats (control). For 20 following days it was preceded to the ana1ysis ofthe estrous cycle through the collection of vaginal smears. Females in estrus were selected for collection and processing of organs, employing microscopic and morphometric techniques. The VChA and VChB rats show irregular estrous cycle. The In region of treated rats presented cytoplasmic vacuoles and dilated cisterna, nuclei with irregular forms and lipid droplets. The I region showed altered electrondensity and irregular distribution ofthe cilia, and the characteristics mentioned in the In region. The A region showed increase of lamellar bodies and lipid droplets in the cytoplasm and lumen of the epithelium. The Inf and F of treated rats showed vacuoles and lacunas with content or not in their interiors, non-preserved mitochondria, lamellar bodies, lipid droplets and dilated cisterna. There were observed nuclei with irregular forms and nuclei and cytoplasmic content in the lumen of the epithelium. Morphology of the cilia was observed to be altered. The degenera tive process acquired growing proportions ftom the VChA group to the VChB one. Treated groups presented smaller cytoplasmic and nuclear areas compared to the controI. It's concluded that ethanol alters the estrous cyc1e and the epithelial cell structure of uterine tube. Due the alterations, the fertilization and the capacitation process of ethanol-drinking rats are damaged. Yet it is inferred that due to the great quantity of lysosomes and formation of vacuoles, alcohol initially leads to cell death different ftom the apoptosis Advisors/Committee Members: UNIVERSIDADE ESTADUAL DE CAMPINAS (CRUESP), Martinez, Francisco Eduardo (advisor), Universidade Estadual de Campinas. Instituto de Biologia (institution), Miglino, Maria Angelica (committee member), Stefanini, Maira Aparecida (committee member), Cagnon, Valéria Helena Alves (committee member), Camargo, Isabel Cristina Cherici (committee member).

Subjects/Keywords: Estro; Histologia; Ultraestrutura; Álcool; Tubas uterinas; Rato UChA; Rato UChB; Estrus; Histology; Ultrastructure; Uterine tube; Ethanol; Fallopian tubes; UChA rat; UChB rat

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Almeida-Francia, C. C. D. d. (2005). Ciclo estral, histologia e ultra-estrutura do epitelio da tuba uterina da linhagem de ratos UChA e UChB (bebedores voluntarios de etanol): Estrous cycle, histology and ultrastructure of the uterine tube epithelium of UChA and UChB rats lineage (ethanol voluntary consumers). (Thesis). Universidade Estadual de Campinas. Retrieved from http://repositorio.unicamp.br/jspui/handle/REPOSIP/317532

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Almeida-Francia, Camila Contin Diniz de. “Ciclo estral, histologia e ultra-estrutura do epitelio da tuba uterina da linhagem de ratos UChA e UChB (bebedores voluntarios de etanol): Estrous cycle, histology and ultrastructure of the uterine tube epithelium of UChA and UChB rats lineage (ethanol voluntary consumers).” 2005. Thesis, Universidade Estadual de Campinas. Accessed October 22, 2020. http://repositorio.unicamp.br/jspui/handle/REPOSIP/317532.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Almeida-Francia, Camila Contin Diniz de. “Ciclo estral, histologia e ultra-estrutura do epitelio da tuba uterina da linhagem de ratos UChA e UChB (bebedores voluntarios de etanol): Estrous cycle, histology and ultrastructure of the uterine tube epithelium of UChA and UChB rats lineage (ethanol voluntary consumers).” 2005. Web. 22 Oct 2020.

Vancouver:

Almeida-Francia CCDd. Ciclo estral, histologia e ultra-estrutura do epitelio da tuba uterina da linhagem de ratos UChA e UChB (bebedores voluntarios de etanol): Estrous cycle, histology and ultrastructure of the uterine tube epithelium of UChA and UChB rats lineage (ethanol voluntary consumers). [Internet] [Thesis]. Universidade Estadual de Campinas; 2005. [cited 2020 Oct 22]. Available from: http://repositorio.unicamp.br/jspui/handle/REPOSIP/317532.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Almeida-Francia CCDd. Ciclo estral, histologia e ultra-estrutura do epitelio da tuba uterina da linhagem de ratos UChA e UChB (bebedores voluntarios de etanol): Estrous cycle, histology and ultrastructure of the uterine tube epithelium of UChA and UChB rats lineage (ethanol voluntary consumers). [Thesis]. Universidade Estadual de Campinas; 2005. Available from: http://repositorio.unicamp.br/jspui/handle/REPOSIP/317532

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

.