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University of Waterloo
1.
Safati, Adrian.
Contextual cues as modifiers of cTBS effects on indulgent eating.
Degree: 2019, University of Waterloo
URL: http://hdl.handle.net/10012/14846
► Background: Prior studies have found that continuous theta burst stimulation (cTBS) targeting the left dlPFC results in reliable increases in consumption of calorie-dense food items.…
(more)
▼ Background: Prior studies have found that continuous theta burst stimulation (cTBS) targeting the left dlPFC results in reliable increases in consumption of calorie-dense food items. However, it is not known to what extent such effects are modified by cues in the immediate eating environment. Tempting environments (i.e., those saturated with appetitive eating cues) may lead to more reliance on cognitive control networks involving the dlPFC, thereby enhancing cTBS effects on indulgent eating.
Objective/Hypothesis: The objective was to examine the extent to which cTBS effects on indulgent eating would be modified by contextual cues. It was hypothesized that cTBS effects would be stronger in the presence of facilitating cues.
Methods: Using a single-blinded between-subjects factorial design, 107 TMS-naïve adults were randomly assigned to one of four conditions: 1) active cTBS + facilitating cues, 2) sham cTBS + facilitating cues, 3) active cTBS + inhibiting cues, 4) sham cTBS + inhibiting cues. Following stimulation participants completed a flanker paradigm and a taste test during which quantity consumed was assessed surreptitiously.
Results: Findings revealed a significant interaction between stimulation and cue type (F(1,102)=6.235, p=.014), such that cTBS resulted in increased food consumption (compared to sham) in the presence of the facilitating cue but not in the presence of the inhibiting cue. Moderated mediational analyses showed selective mediation of cTBS effects on consumption through cTBS attenuation of flanker interference scores.
Conclusions: The effects of cTBS on indulgent eating are strengthened in the presence of facilitating cues. Methodologically speaking, facilitating cues may be a functional prerequisite for exploring cTBS effects on eating in the laboratory. Substantively, the findings also suggest that facilitating cues in the eating environment may amplify counter-intentional food indulgence in everyday life via cognitive control failure.
Subjects/Keywords: TMS; eating; brain stimulation; transcranial magnetic stimulation
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APA ·
Chicago ·
MLA ·
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APA (6th Edition):
Safati, A. (2019). Contextual cues as modifiers of cTBS effects on indulgent eating. (Thesis). University of Waterloo. Retrieved from http://hdl.handle.net/10012/14846
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Safati, Adrian. “Contextual cues as modifiers of cTBS effects on indulgent eating.” 2019. Thesis, University of Waterloo. Accessed March 05, 2021.
http://hdl.handle.net/10012/14846.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Safati, Adrian. “Contextual cues as modifiers of cTBS effects on indulgent eating.” 2019. Web. 05 Mar 2021.
Vancouver:
Safati A. Contextual cues as modifiers of cTBS effects on indulgent eating. [Internet] [Thesis]. University of Waterloo; 2019. [cited 2021 Mar 05].
Available from: http://hdl.handle.net/10012/14846.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Safati A. Contextual cues as modifiers of cTBS effects on indulgent eating. [Thesis]. University of Waterloo; 2019. Available from: http://hdl.handle.net/10012/14846
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Ontario Institute of Technology
2.
Raj, Amita.
Modulation of corticospinal excitability during arm cycling in humans.
Degree: 2013, University of Ontario Institute of Technology
URL: http://hdl.handle.net/10155/341
► Animal studies have shown that the basic pattern for locomotor activities are generated via neural networks found in the spinal cord, referred to as central…
(more)
▼ Animal studies have shown that the basic pattern for locomotor activities are
generated via neural networks found in the spinal cord, referred to as central
pattern generators (CPGs) (Grillner, 1981). In humans, accumulating research
evidence suggests that primates, including man, have a similar locomotor centre as
animals that controlled by CPGs (Petersen et. al., 1998). It???s indicative that CPGs are
sufficient to enable locomotion in quadrupeds; however a more extensive cortical
input is involved in the production of locomotion and/or cycling in humans (Zehr et.
al 2004). Advanced methods such as
transcranial magnetic stimulation (
TMS) and
transmastoid electrical
stimulation were implemented to examine supraspinal and
spinal excitability, and bridge the gap between animal and human research.
Therefore, this thesis set out to determine changes in corticospinal excitability in
biceps brachii during different motor outputs, including those generated by spinal
CPGs.
The major findings from the present study suggest that corticospinal excitability is
enhanced, in biceps brachii, during the initiation of the flexion phase of arm cycling
when compared to an intensity matched contraction. The results also proposed that
spinal mechanisms are the dominant factors which drive task- and phase-dependent
modulation of corticospinal excitability during arm cycling.
Advisors/Committee Members: Power, Kevin, Murphy, Bernadette.
Subjects/Keywords: Cycling; Supraspinal; Spinal; Transcranial magnetic stimulation (TMS); Transmastoid electrical stimulation
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Raj, A. (2013). Modulation of corticospinal excitability during arm cycling in humans. (Thesis). University of Ontario Institute of Technology. Retrieved from http://hdl.handle.net/10155/341
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Raj, Amita. “Modulation of corticospinal excitability during arm cycling in humans.” 2013. Thesis, University of Ontario Institute of Technology. Accessed March 05, 2021.
http://hdl.handle.net/10155/341.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Raj, Amita. “Modulation of corticospinal excitability during arm cycling in humans.” 2013. Web. 05 Mar 2021.
Vancouver:
Raj A. Modulation of corticospinal excitability during arm cycling in humans. [Internet] [Thesis]. University of Ontario Institute of Technology; 2013. [cited 2021 Mar 05].
Available from: http://hdl.handle.net/10155/341.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Raj A. Modulation of corticospinal excitability during arm cycling in humans. [Thesis]. University of Ontario Institute of Technology; 2013. Available from: http://hdl.handle.net/10155/341
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Vilnius University
3.
Valiulis, Vladas.
Transkranijinės magnetinės stimuliacijos įtaka
galvos smegenų bioelektriniam aktyvumui.
Degree: Dissertation, Biophysics, 2014, Vilnius University
URL: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2014~D_20140925_135031-16126
;
► Transkranijinė magnetinė stimuliacija (TMS) – tai modernus neinvazinis vaistams rezistentiškų psichiatrinių sutrikimų gydymo būdas. Fiziologiniai TMS tyrimai pasižymi įvairiais, dažnai prieštaringais rezultatais, daugeliu atvejų didžiausias…
(more)
▼ Transkranijinė magnetinė stimuliacija (TMS)
– tai modernus neinvazinis vaistams rezistentiškų psichiatrinių
sutrikimų gydymo būdas. Fiziologiniai TMS tyrimai pasižymi
įvairiais, dažnai prieštaringais rezultatais, daugeliu atvejų
didžiausias dėmesys skiriamas betarpiškiems poveikiams po vienos
TMS procedūros, bet ne po pilno terapinio kurso. Manoma, kad
rezultatų įvairovę TMS praktikoje įtakoja skirtingi stimuliacijos
parametrai ir netikslumai parenkant stimuliuojamą zoną smegenyse.
Nors TMS terapija dažnai traktuojama kaip švelnesnė alternatyva
elektros impulsų terapijai (EIT), palyginamųjų fiziologinių šių
metodikų tyrimų labai trūksta. Darbo tikslas buvo įvertinti TMS
terapijos kurso poveikį bioelektriniam galvos smegenų aktyvumui ir
palyginti jį su EIT terapijos poveikiu. Buvo tirta aukšto ir žemo
dažnių (10 Hz ir 1 Hz) TMS terapijos įtaka EEG dažnių galios
spektrui bei sukeltiniam klausos potencialui P300, naudojant
standartinį ir neuronavigacinį taikinio pozicionavimą. TMS sukelti
EEG pokyčiai palyginti su EIT terapijos sukeltais EEG pokyčiais,
išmatuota TMS terapijos sąlygotų pokyčių dinamika kelių mėnesių
bėgyje. Rezultatai parodė, kad TMS terapijos pasekoje smegenyse
ryškiausiai padidėja delta dažnio galia. Naudojant standartinį
pozicionavimą 10 Hz TMS sukėlė įvairesnius ir intensyvesnius EEG
galios spektro pokyčius nei 1 Hz TMS. Pritaikius neuronavigacinę
sistemą 10 Hz TMS atveju sumažėjo teta ir alfa dažnių galios
pokyčiai. Praėjus keliems mėnesiams nuo TMS... [toliau žr. visą
tekstą]
Transcranial magnetic stimulation (TMS) is a
modern non invasive method of drug resistant psychiatric disorder
treatment. TMS physiology research is hindered by variable, often
controversial results. In most studies main attention is being
focused on immediate effects after single TMS procedure rather than
the influence of a complete therapy course. It is considered that
variability of results in TMS practice is caused by different
stimulation parameters and imprecision of stimulated area placement
in the brain. Although TMS therapy is often viewed as a milder
alternative to electroconvulsive therapy (ECT), comparative
physiological studies of these two methods are very rare. The aim
of this study was to evaluate the effect of rTMS therapy course on
bioelectrical brain activity and compare it to an ECT effect.
Research included the effect of high and low frequency (10 Hz and 1
Hz) TMS on EEG band power spectrum and auditory evoked potential
P300, using both standard and neuronavigated target positioning.
TMS evoked EEG changes were also compared to the changes of ECT.
Change dynamics after several months of TMS therapy were also
measured. Results showed that after TMS therapy the most notable
change in the brain occurs in the form of delta power increase.
When using standard positioning 10 Hz TMS evokes more diverse and
intense EEG band power spectrum changes than the 1 Hz TMS.
Application of neuronavigation system decreases theta and alpha
band power changes in 10 Hz TMS... [to full
text]
Advisors/Committee Members: BULATOV, ALEKSANDR (Doctoral dissertation committee chair), ALABURDA, AIDAS (Doctoral dissertation committee member), GRIŠKOVA-BULANOVA, INGA (Doctoral dissertation committee member), GERMANAVIČIUS, ARŪNAS (Doctoral dissertation committee member), KOROSTENSKAJA, MILENA (Doctoral dissertation committee member), DAPŠYS, KASTYTIS (Doctoral dissertation supervisor).
Subjects/Keywords: TMS; EEG; P300; EIT; Transkranijinė magnetinė
stimuliacija; TMS; EEG; P300; ECT; Transcranial magnetic
stimulation
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Valiulis, V. (2014). Transkranijinės magnetinės stimuliacijos įtaka
galvos smegenų bioelektriniam aktyvumui. (Doctoral Dissertation). Vilnius University. Retrieved from http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2014~D_20140925_135031-16126 ;
Chicago Manual of Style (16th Edition):
Valiulis, Vladas. “Transkranijinės magnetinės stimuliacijos įtaka
galvos smegenų bioelektriniam aktyvumui.” 2014. Doctoral Dissertation, Vilnius University. Accessed March 05, 2021.
http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2014~D_20140925_135031-16126 ;.
MLA Handbook (7th Edition):
Valiulis, Vladas. “Transkranijinės magnetinės stimuliacijos įtaka
galvos smegenų bioelektriniam aktyvumui.” 2014. Web. 05 Mar 2021.
Vancouver:
Valiulis V. Transkranijinės magnetinės stimuliacijos įtaka
galvos smegenų bioelektriniam aktyvumui. [Internet] [Doctoral dissertation]. Vilnius University; 2014. [cited 2021 Mar 05].
Available from: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2014~D_20140925_135031-16126 ;.
Council of Science Editors:
Valiulis V. Transkranijinės magnetinės stimuliacijos įtaka
galvos smegenų bioelektriniam aktyvumui. [Doctoral Dissertation]. Vilnius University; 2014. Available from: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2014~D_20140925_135031-16126 ;

Vilnius University
4.
Valiulis, Vladas.
The effect of transcranial magnetic stimulation on
brain bioelectrical activity.
Degree: PhD, Biophysics, 2014, Vilnius University
URL: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2014~D_20140925_135043-14839
;
► Transcranial magnetic stimulation (TMS) is a modern non invasive method of drug resistant psychiatric disorder treatment. TMS physiology research is hindered by variable, often controversial…
(more)
▼ Transcranial magnetic stimulation (TMS) is a
modern non invasive method of drug resistant psychiatric disorder
treatment. TMS physiology research is hindered by variable, often
controversial results. In most studies main attention is being
focused on immediate effects after single TMS procedure rather than
the influence of a complete therapy course. It is considered that
variability of results in TMS practice is caused by different
stimulation parameters and imprecision of stimulated area placement
in the brain. Although TMS therapy is often viewed as a milder
alternative to electroconvulsive therapy (ECT), comparative
physiological studies of these two methods are very rare. The aim
of this study was to evaluate the effect of rTMS therapy course on
bioelectrical brain activity and compare it to an ECT effect.
Research included the effect of high and low frequency (10 Hz and 1
Hz) TMS on EEG band power spectrum and auditory evoked potential
P300, using both standard and neuronavigated target positioning.
TMS evoked EEG changes were also compared to the changes of ECT.
Change dynamics after several months of TMS therapy were also
measured. Results showed that after TMS therapy the most notable
change in the brain occurs in the form of delta power increase.
When using standard positioning 10 Hz TMS evokes more diverse and
intense EEG band power spectrum changes than the 1 Hz TMS.
Application of neuronavigation system decreases theta and alpha
band power changes in 10 Hz TMS... [to full
text]
Transkranijinė magnetinė stimuliacija (TMS)
– tai modernus neinvazinis vaistams rezistentiškų psichiatrinių
sutrikimų gydymo būdas. Fiziologiniai TMS tyrimai pasižymi
įvairiais, dažnai prieštaringais rezultatais, daugeliu atvejų
didžiausias dėmesys skiriamas betarpiškiems poveikiams po vienos
TMS procedūros, bet ne po pilno terapinio kurso. Manoma, kad
rezultatų įvairovę TMS praktikoje įtakoja skirtingi stimuliacijos
parametrai ir netikslumai parenkant stimuliuojamą zoną smegenyse.
Nors TMS terapija dažnai traktuojama kaip švelnesnė alternatyva
elektros impulsų terapijai (EIT), palyginamųjų fiziologinių šių
metodikų tyrimų labai trūksta. Darbo tikslas buvo įvertinti TMS
terapijos kurso poveikį bioelektriniam galvos smegenų aktyvumui ir
palyginti jį su EIT terapijos poveikiu. Buvo tirta aukšto ir žemo
dažnių (10 Hz ir 1 Hz) TMS terapijos įtaka EEG dažnių galios
spektrui bei sukeltiniam klausos potencialui P300, naudojant
standartinį ir neuronavigacinį taikinio pozicionavimą. TMS sukelti
EEG pokyčiai palyginti su EIT terapijos sukeltais EEG pokyčiais,
išmatuota TMS terapijos sąlygotų pokyčių dinamika kelių mėnesių
bėgyje. Rezultatai parodė, kad TMS terapijos pasekoje smegenyse
ryškiausiai padidėja delta dažnio galia. Naudojant standartinį
pozicionavimą 10 Hz TMS sukėlė įvairesnius ir intensyvesnius EEG
galios spektro pokyčius nei 1 Hz TMS. Pritaikius neuronavigacinę
sistemą 10 Hz TMS atveju sumažėjo teta ir alfa dažnių galios
pokyčiai. Praėjus keliems mėnesiams nuo TMS... [toliau žr. visą
tekstą]
Advisors/Committee Members: BULATOV, ALEKSANDR (Doctoral dissertation committee chair), ALABURDA, AIDAS (Doctoral dissertation committee member), GRIŠKOVA-BULANOVA, INGA (Doctoral dissertation committee member), GERMANAVIČIUS, ARŪNAS (Doctoral dissertation committee member), KOROSTENSKAJA, MILENA (Doctoral dissertation committee member), DAPŠYS, KASTYTIS (Doctoral dissertation supervisor).
Subjects/Keywords: TMS; EEG; P300; ECT; Transcranial magnetic
stimulation; TMS; EEG; P300; EIT; Transkranijinė magnetinė
stimuliacija
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Record Details
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Valiulis, V. (2014). The effect of transcranial magnetic stimulation on
brain bioelectrical activity. (Doctoral Dissertation). Vilnius University. Retrieved from http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2014~D_20140925_135043-14839 ;
Chicago Manual of Style (16th Edition):
Valiulis, Vladas. “The effect of transcranial magnetic stimulation on
brain bioelectrical activity.” 2014. Doctoral Dissertation, Vilnius University. Accessed March 05, 2021.
http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2014~D_20140925_135043-14839 ;.
MLA Handbook (7th Edition):
Valiulis, Vladas. “The effect of transcranial magnetic stimulation on
brain bioelectrical activity.” 2014. Web. 05 Mar 2021.
Vancouver:
Valiulis V. The effect of transcranial magnetic stimulation on
brain bioelectrical activity. [Internet] [Doctoral dissertation]. Vilnius University; 2014. [cited 2021 Mar 05].
Available from: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2014~D_20140925_135043-14839 ;.
Council of Science Editors:
Valiulis V. The effect of transcranial magnetic stimulation on
brain bioelectrical activity. [Doctoral Dissertation]. Vilnius University; 2014. Available from: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2014~D_20140925_135043-14839 ;

University of Toronto
5.
Lam, Susy.
Effects of Age and Motor Training on Prefrontal-motor Cortical Excitability.
Degree: 2015, University of Toronto
URL: http://hdl.handle.net/1807/70330
► The dorsolateral prefrontal cortex (DLPFC) is a critical substrate for motor learning. However, how DLPFC is involved in goal-directed, sequence-specific learning remains unclear, and effects…
(more)
▼ The dorsolateral prefrontal cortex (DLPFC) is a critical substrate for motor learning. However, how DLPFC is involved in goal-directed, sequence-specific learning remains unclear, and effects of age on learning and DLPFC-to-primary motor cortex (M1) connections have not been tested. We studied 14 right-handed healthy subjects, 20-80 years old, in a combined TMS-pinch experiment. We examined DLPFC-M1 connections in human subjects and how they change with motor training, whether sequence training changes M1 intracortical and DLPFC-M1 neurophysiology differently than motor training not containing a sequence, and whether age influences the TMS neurophysiological measures. All subjects were unable to regenerate the sequence, and behavioural/TMS measures suggest that they implicitly acquired the sequence. Sequence acquisition correlated with DLPFC-M1 facilitation. The results suggest that the brain processes sequence information differently from non-specific information during motor training. The DLPFC may play a role in processing sequence-specific information through an excitatory functional connection to M1 during acquisition.
M.Sc.
Advisors/Committee Members: Chen, Robert, Medical Science.
Subjects/Keywords: aging; DLPFC; motor learning; neurophysiology; tms; transcranial magnetic stimulation; 0317
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Lam, S. (2015). Effects of Age and Motor Training on Prefrontal-motor Cortical Excitability. (Masters Thesis). University of Toronto. Retrieved from http://hdl.handle.net/1807/70330
Chicago Manual of Style (16th Edition):
Lam, Susy. “Effects of Age and Motor Training on Prefrontal-motor Cortical Excitability.” 2015. Masters Thesis, University of Toronto. Accessed March 05, 2021.
http://hdl.handle.net/1807/70330.
MLA Handbook (7th Edition):
Lam, Susy. “Effects of Age and Motor Training on Prefrontal-motor Cortical Excitability.” 2015. Web. 05 Mar 2021.
Vancouver:
Lam S. Effects of Age and Motor Training on Prefrontal-motor Cortical Excitability. [Internet] [Masters thesis]. University of Toronto; 2015. [cited 2021 Mar 05].
Available from: http://hdl.handle.net/1807/70330.
Council of Science Editors:
Lam S. Effects of Age and Motor Training on Prefrontal-motor Cortical Excitability. [Masters Thesis]. University of Toronto; 2015. Available from: http://hdl.handle.net/1807/70330

Colorado State University
6.
Vaughn, Heather Noelle.
Establishing differences in intracortical inhibition and excitation between individuals with and without stroke.
Degree: MS(M.S.), Occupational Therapy, 2013, Colorado State University
URL: http://hdl.handle.net/10217/81068
► Background and purpose: Even though there is much information and research on neuroplasticity, many questions remain unanswered about how the brain changes and recovers after…
(more)
▼ Background and purpose: Even though there is much information and research on neuroplasticity, many questions remain unanswered about how the brain changes and recovers after a stroke.
Transcranial magnetic stimulation (
TMS) has been used as the primary method of direct
stimulation to assess change especially in the primary motor cortex because it allows for study of the specific excitatory and inhibitory mechanisms. The purpose of this study was to investigate and identify differences in
TMS-induced intracortical inhibition and facilitation when comparing survivors of stroke to individuals unaffected by stroke. Methods: Fourteen subjects who had experienced a stroke and 19 non-stroke subjects were investigated using single and paired-pulse
TMS.
TMS was applied over the affected hemisphere for subjects with stroke and over the dominant hemisphere of the non-stroke subjects. Resting motor threshold (MT) was established. Forty motor evoked potentials (MEPs) were collected from the first dorsal interosseus muscle, using surface electrodes, for each
subject. These were subdivided into 10 trials of single-pulse conditioning stimulus, 10 trials of single-pulse test stimulus (TS), 10 paired-pulse intracortical facilitation (ICF), 10 paired-pulse intracortical inhibition (ICI); the order of
stimulation condition for the 40 trials was randomized. Results: The stroke group exhibited significantly higher MT and significantly lower motor evoked potential amplitudes for TS, ICF, and ICI specific trials compared to the group without stroke. Finally, the ratio of ICF to ICI was found to be significantly lower in the stroke group, indicating less facilitation. Conclusion: Overall the affected hemispheres of the participants surviving stroke were found to be significantly less excitable than the dominant hemispheres of the non-stroke participants. These findings and the usefulness of
TMS to directly access and assess differences in the brain's baseline excitability following stroke will hopefully add to existing knowledge that informs therapeutic interventions aimed at increasing post-stroke performance in daily activities.
Advisors/Committee Members: Greene, David (advisor), Malcolm, Matt (committee member), Davalos, Deana (committee member).
Subjects/Keywords: intracortical inhibition; transcranial magnetic stimulation; TMS; stroke; intracortical facilitation
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Vaughn, H. N. (2013). Establishing differences in intracortical inhibition and excitation between individuals with and without stroke. (Masters Thesis). Colorado State University. Retrieved from http://hdl.handle.net/10217/81068
Chicago Manual of Style (16th Edition):
Vaughn, Heather Noelle. “Establishing differences in intracortical inhibition and excitation between individuals with and without stroke.” 2013. Masters Thesis, Colorado State University. Accessed March 05, 2021.
http://hdl.handle.net/10217/81068.
MLA Handbook (7th Edition):
Vaughn, Heather Noelle. “Establishing differences in intracortical inhibition and excitation between individuals with and without stroke.” 2013. Web. 05 Mar 2021.
Vancouver:
Vaughn HN. Establishing differences in intracortical inhibition and excitation between individuals with and without stroke. [Internet] [Masters thesis]. Colorado State University; 2013. [cited 2021 Mar 05].
Available from: http://hdl.handle.net/10217/81068.
Council of Science Editors:
Vaughn HN. Establishing differences in intracortical inhibition and excitation between individuals with and without stroke. [Masters Thesis]. Colorado State University; 2013. Available from: http://hdl.handle.net/10217/81068

Queens University
7.
Choi, Elaine.
The Effects of Electroconvulsive Therapy or Repetitive Transcranial Magnetic Stimulation on Olfactory Sensitivity and Identification in Individuals with Depression
.
Degree: Neuroscience Studies, 2015, Queens University
URL: http://hdl.handle.net/1974/13455
► Background: Previous research has found links between olfactory deficits and depression. Olfactory ability is restored with successful treatment with antidepressant medication. Electroconvulsive therapy (ECT) and…
(more)
▼ Background: Previous research has found links between olfactory deficits and depression. Olfactory ability is restored with successful treatment with antidepressant medication. Electroconvulsive therapy (ECT) and repetitive transcranial magnetic stimulation (rTMS) are two effective treatments for depression. It is not known whether these somatic treatments may, similarly to pharmacotherapy, restore olfactory sensitivity and identification ability in individuals with depression.
Objectives: The objective of the present study was to determine whether treatment with ECT or rTMS is associated with improvement in olfactory sensitivity or identification in individuals with depression.
Methods: Six patients receiving ECT and three patients receiving rTMS completed the study. Before beginning treatment and 20-30 days after their first treatment, patients were assessed using the Smell Threshold Test (STT), Smell Identification Test (SIT), Hamilton Depression Rating Scale (HDRS), Beck Depression Inventory (BDI), and Snaith-Hamilton Pleasure Scale (SHPS). The control group consisted of nine matched healthy participants.
Results: There was no significant difference between the ECT, rTMS, and control groups for olfactory sensitivity either before or after treatment. At both testing visits, the rTMS group performed significantly worse on olfactory identification compared to control, while the ECT group performed comparably to control. Olfactory identification ability was significantly correlated with HDRS score at baseline but not after treatment. Olfactory performance was not correlated with BDI or SHPS score.
Conclusions: The results of this pilot study suggest that individuals with depression may not have decreased olfactory sensitivity ability compared to healthy controls. However, in those who do exhibit poor olfactory identification, rTMS may be effective in restoring sense of smell. Further research is needed to determine whether olfactory deficits are caused by depressive symptoms, and whether ECT may also restore olfaction in individuals who have olfactory deficits. Determining the links between olfaction and depression may be important for promoting the early diagnosis and treatment of depression, and for improving quality of life and everyday functioning.
Subjects/Keywords: Transcranial Magnetic Stimulation (TMS)
;
Olfaction
;
Neuroscience
;
Psychiatry
;
Depression
;
Smell
;
Olfactory
;
Electroconvulsive Therapy (ECT)
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Choi, E. (2015). The Effects of Electroconvulsive Therapy or Repetitive Transcranial Magnetic Stimulation on Olfactory Sensitivity and Identification in Individuals with Depression
. (Thesis). Queens University. Retrieved from http://hdl.handle.net/1974/13455
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Choi, Elaine. “The Effects of Electroconvulsive Therapy or Repetitive Transcranial Magnetic Stimulation on Olfactory Sensitivity and Identification in Individuals with Depression
.” 2015. Thesis, Queens University. Accessed March 05, 2021.
http://hdl.handle.net/1974/13455.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Choi, Elaine. “The Effects of Electroconvulsive Therapy or Repetitive Transcranial Magnetic Stimulation on Olfactory Sensitivity and Identification in Individuals with Depression
.” 2015. Web. 05 Mar 2021.
Vancouver:
Choi E. The Effects of Electroconvulsive Therapy or Repetitive Transcranial Magnetic Stimulation on Olfactory Sensitivity and Identification in Individuals with Depression
. [Internet] [Thesis]. Queens University; 2015. [cited 2021 Mar 05].
Available from: http://hdl.handle.net/1974/13455.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Choi E. The Effects of Electroconvulsive Therapy or Repetitive Transcranial Magnetic Stimulation on Olfactory Sensitivity and Identification in Individuals with Depression
. [Thesis]. Queens University; 2015. Available from: http://hdl.handle.net/1974/13455
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Toronto
8.
Bakker, Nathaniel Thomas.
Resting-state Functional Connectivity Predicts Individual Treatment Outcomes of Repetitive Transcranial Magnetic Stimulation for Major Depressive Disorder.
Degree: 2014, University of Toronto
URL: http://hdl.handle.net/1807/71481
► Repetitive transcranial magnetic stimulation (rTMS) is an emerging treatment for treatment-resistant major depressive disorder (MDD). We recently found that treatment response to rTMS of the…
(more)
▼ Repetitive transcranial magnetic stimulation (rTMS) is an emerging treatment for treatment-resistant major depressive disorder (MDD). We recently found that treatment response to rTMS of the dorsomedial prefrontal cortex (DMPFC) was bimodal, with individual patients showing either minimal or marked improvement (Downar et al., 2013). Here, we tested whether treatment response could be predicted before initiating treatment. To this end, we trained support vector machine (SVM) classifiers on whole-brain resting-state functional connectivity magnetic resonance imaging (rs-fcMRI) data to learn the treatment outcomes of 41 patients who received rTMS of the DMPFC. The SVMs classified patients with 90% accuracy (p = 0.035, corrected). Classification was based on 9 functional connections, with a pattern of positive and negative functional connectivity in non-responders and responders, respectively. This study represents the first step towards developing a screening tool that can direct treatment decisions.
M.Sc.
Advisors/Committee Members: Downar, Jonathan, Medical Science.
Subjects/Keywords: depression; dmpfc; dorsomedial prefrontal cortex; support vector machine; tms; transcranial magnetic stimulation; 0317
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Bakker, N. T. (2014). Resting-state Functional Connectivity Predicts Individual Treatment Outcomes of Repetitive Transcranial Magnetic Stimulation for Major Depressive Disorder. (Masters Thesis). University of Toronto. Retrieved from http://hdl.handle.net/1807/71481
Chicago Manual of Style (16th Edition):
Bakker, Nathaniel Thomas. “Resting-state Functional Connectivity Predicts Individual Treatment Outcomes of Repetitive Transcranial Magnetic Stimulation for Major Depressive Disorder.” 2014. Masters Thesis, University of Toronto. Accessed March 05, 2021.
http://hdl.handle.net/1807/71481.
MLA Handbook (7th Edition):
Bakker, Nathaniel Thomas. “Resting-state Functional Connectivity Predicts Individual Treatment Outcomes of Repetitive Transcranial Magnetic Stimulation for Major Depressive Disorder.” 2014. Web. 05 Mar 2021.
Vancouver:
Bakker NT. Resting-state Functional Connectivity Predicts Individual Treatment Outcomes of Repetitive Transcranial Magnetic Stimulation for Major Depressive Disorder. [Internet] [Masters thesis]. University of Toronto; 2014. [cited 2021 Mar 05].
Available from: http://hdl.handle.net/1807/71481.
Council of Science Editors:
Bakker NT. Resting-state Functional Connectivity Predicts Individual Treatment Outcomes of Repetitive Transcranial Magnetic Stimulation for Major Depressive Disorder. [Masters Thesis]. University of Toronto; 2014. Available from: http://hdl.handle.net/1807/71481

Deakin University
9.
Moreland, Ashleigh T.
Improving neural function in older adults through targeted exercise.
Degree: School of Exercise and Nutrition Sciences, 2016, Deakin University
URL: http://hdl.handle.net/10536/DRO/DU:30102805
► This thesis explored age-related differences in neurophysiological function, and identified and compared the efficacy and time-course of adaptations following externally-paced strength training, balance and visuomotor…
(more)
▼ This thesis explored age-related differences in neurophysiological function, and identified and compared the efficacy and time-course of adaptations following externally-paced strength training, balance and visuomotor training. Older adults were shown to have functional deficits compared to young adults, but the interventions induced neuroplasticity and resulted in improved functional outcomes.
Advisors/Committee Members: Daly Robin, Wei-Peng Teo, Kidgell Dawson.
Subjects/Keywords: maladaptive neuroplasticity; short-interval intracortical inhibition (SICI); motor evoked potential (MEP); transcranial magnetic stimulation (TMS)
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Moreland, A. T. (2016). Improving neural function in older adults through targeted exercise. (Thesis). Deakin University. Retrieved from http://hdl.handle.net/10536/DRO/DU:30102805
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Moreland, Ashleigh T. “Improving neural function in older adults through targeted exercise.” 2016. Thesis, Deakin University. Accessed March 05, 2021.
http://hdl.handle.net/10536/DRO/DU:30102805.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Moreland, Ashleigh T. “Improving neural function in older adults through targeted exercise.” 2016. Web. 05 Mar 2021.
Vancouver:
Moreland AT. Improving neural function in older adults through targeted exercise. [Internet] [Thesis]. Deakin University; 2016. [cited 2021 Mar 05].
Available from: http://hdl.handle.net/10536/DRO/DU:30102805.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Moreland AT. Improving neural function in older adults through targeted exercise. [Thesis]. Deakin University; 2016. Available from: http://hdl.handle.net/10536/DRO/DU:30102805
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Ontario Institute of Technology
10.
Dancey, Erin.
The effect of experimental pain on neural function and motor learning.
Degree: 2017, University of Ontario Institute of Technology
URL: http://hdl.handle.net/10155/786
► This thesis investigated whether acute experimental pain interacts with motor learning acquisition to create adaptive and maladaptive changes in neural function. The first study consisted…
(more)
▼ This thesis investigated whether acute experimental pain interacts with motor learning acquisition to create adaptive and maladaptive changes in neural function. The first study consisted of two experiments where we determined the interactive effects of acute pain versus control (Experiment 1) and local versus remote acute pain (Experiment 2) on motor learning and sensorimotor processing and provided supportive evidence for early somatosensory evoked potential (SEP) peaks as markers for sensorimotor integration (SMI) and acute pain. Motor performance was better in the presence of pain pre-motor learning and motor learning retention improved in the presence of local pain. A limitation of this first study was that performance saturation occurred and therefore we used a more complex tracing task for the subsequent studies. Our second SEP study The interactive effect of acute pain and motor learning acquisition on sensorimotor integration and motor learning outcomes provides corroboration for the enhancement of motor learning while in acute pain. In addition, the changes in the amplitudes of SEP peaks suggests that SEP peak alterations reflect neurophysiological alterations accompanying both motor learning acquisition and mild acute pain. Improved motor learning acquisition during acute pain may be the result of increased attention or increased arousal, and therefore we concluded that it was important to compare the effects of local versus remote versus contralateral acute pain in conjunction with a complex motor learning task which was the focus of the third study. Our third study found that motor learning occurred in the presence of mild acute pain and there were no significant differences in motor learning acquisition or retention between three groups that had capsaicin applied at different locations. We hypothesized that improved motor learning acquisition during acute pain may have been caused through increased arousal. For the fourth study we explored the effect of acute pain on neuroplasticity of the motor cortex (MI) by using input-output curves elicited via
transcranial magnetic stimulation (
TMS). The acute pain in this study was shown to negate the increase in slope that was observed for the control group despite having a positive impact on motor learning acquisition.
Advisors/Committee Members: Murphy, Bernadette, Yielder, Paul.
Subjects/Keywords: Acute pain; Motor learning; Somatosensory evoked potentials (SEPs); Transcranial magnetic stimulation (TMS)
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Dancey, E. (2017). The effect of experimental pain on neural function and motor learning. (Thesis). University of Ontario Institute of Technology. Retrieved from http://hdl.handle.net/10155/786
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Dancey, Erin. “The effect of experimental pain on neural function and motor learning.” 2017. Thesis, University of Ontario Institute of Technology. Accessed March 05, 2021.
http://hdl.handle.net/10155/786.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Dancey, Erin. “The effect of experimental pain on neural function and motor learning.” 2017. Web. 05 Mar 2021.
Vancouver:
Dancey E. The effect of experimental pain on neural function and motor learning. [Internet] [Thesis]. University of Ontario Institute of Technology; 2017. [cited 2021 Mar 05].
Available from: http://hdl.handle.net/10155/786.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Dancey E. The effect of experimental pain on neural function and motor learning. [Thesis]. University of Ontario Institute of Technology; 2017. Available from: http://hdl.handle.net/10155/786
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
11.
Schaffer, Daniel Robert.
Testing the Efficacy of Transcranial Magnetic Stimulation (TMS) in Treating Depression in Patients with Cognitive Impairment.
Degree: MS, Psychology, 2018, Old Dominion University
URL: 9780438496316
;
https://digitalcommons.odu.edu/psychology_etds/75
► The purpose of this study is to (1) examine the efficacy of Transcranial Magnetic Stimulation (TMS) in treating depression among individuals with cognitive impairment…
(more)
▼ The purpose of this study is to (1) examine the efficacy of
Transcranial Magnetic Stimulation (
TMS) in treating depression among individuals with cognitive impairment and (2) to examine if
TMS is capable of facilitating cognitive improvements independent of mood improvements. Mild cognitive impairment (MCI) is often seen as a pre-clinical stage to dementia, and depressive disorders are highly prevalent among both MCI and dementia. There is a large body of research that has linked depressive disorders as a prodromal symptom of MCI and the later development of dementia. While some researchers debate whether or not this link between depression and MCI/dementia is a true prodromal relationship, or if depression is independently comorbid with MCI/dementia, it remains clear that these disorders occur together in high prevalence rates.
The goal of this study was to determine whether or not
Transcranial Magnetic Stimulation (
TMS) might demonstrate treatment efficacy in treating depressive symptoms among individuals who meet MCI criteria.
TMS has been previously approved by the FDA to treat major depressive disorder (MDD); however, very few research studies have been performed to analyze TMS’ ability in treating MDD among individuals with MCI.
By analyzing treatment data from individuals who do and do not meet MCI criteria,
TMS does appear to demonstrate positive treatment efficacy for treating depressive symptoms among individuals who meet MCI criteria.
TMS also appears to be equally efficacious in treating depressive symptoms among this group in comparison to individuals without MCI.
TMS also produces positive changes in neurocognitive functioning, both in the MCI and non-MCI groups; however, the results show that these changes in neurocognitive functioning likely occur as a function of depressive symptom reduction.
Advisors/Committee Members: barbara A. Winstead, Serina A. Neumann, Miguel A. Padilla.
Subjects/Keywords: Depression; Mild cognitive impairment; Neurocognition; TMS; Transcranial magnetic stimulation; Clinical Psychology; Cognitive Psychology; Neurosciences
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Schaffer, D. R. (2018). Testing the Efficacy of Transcranial Magnetic Stimulation (TMS) in Treating Depression in Patients with Cognitive Impairment. (Thesis). Old Dominion University. Retrieved from 9780438496316 ; https://digitalcommons.odu.edu/psychology_etds/75
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Schaffer, Daniel Robert. “Testing the Efficacy of Transcranial Magnetic Stimulation (TMS) in Treating Depression in Patients with Cognitive Impairment.” 2018. Thesis, Old Dominion University. Accessed March 05, 2021.
9780438496316 ; https://digitalcommons.odu.edu/psychology_etds/75.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Schaffer, Daniel Robert. “Testing the Efficacy of Transcranial Magnetic Stimulation (TMS) in Treating Depression in Patients with Cognitive Impairment.” 2018. Web. 05 Mar 2021.
Vancouver:
Schaffer DR. Testing the Efficacy of Transcranial Magnetic Stimulation (TMS) in Treating Depression in Patients with Cognitive Impairment. [Internet] [Thesis]. Old Dominion University; 2018. [cited 2021 Mar 05].
Available from: 9780438496316 ; https://digitalcommons.odu.edu/psychology_etds/75.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Schaffer DR. Testing the Efficacy of Transcranial Magnetic Stimulation (TMS) in Treating Depression in Patients with Cognitive Impairment. [Thesis]. Old Dominion University; 2018. Available from: 9780438496316 ; https://digitalcommons.odu.edu/psychology_etds/75
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Minnesota
12.
Shirinpour, Seyedsina.
Tools for Improving and Understanding Transcranial Magnetic Stimulation.
Degree: PhD, Biomedical Engineering, 2020, University of Minnesota
URL: http://hdl.handle.net/11299/217801
► Transcranial magnetic stimulation (TMS) is a non-invasive brain stimulation technique that can modulate brain activity through a time-varying magnetic field which induces an electric field…
(more)
▼ Transcranial magnetic stimulation (TMS) is a non-invasive brain stimulation technique that can modulate brain activity through a time-varying magnetic field which induces an electric field in the brain. TMS has been used extensively in research and clinical applications because of its ability to non-surgically deliver suprathreshold stimulation to the brain in a safe manner. Despite the popularity of TMS, there are still major gaps in our understanding of how TMS modulates brain activity on a fundamental neuroscience level. Therefore, the TMS mechanism of action is still under investigation. Improved stimulation technology and computational tools have promise for bridging this gap in our understanding. In my dissertation, I developed new methodologies and computational models that advance the current state-of-the-art in TMS and can assist researchers in their future investigations. First, I describe a closed-loop TMS system that can deliver the stimulation based on the instantaneous brain state. This allows researchers to investigate the role of the intrinsic neural activity on the brain’s responsiveness to TMS. To further provide insights into how TMS modulates brain activity at a large brain-scale and the neuronal level, I developed a multi-scale modeling paradigm. Computational simulations have been used extensively to estimate electric fields induced in the brain by TMS, however, their results still need to be validated. To this end, in the second study here, I utilize analytical solutions to evaluate these numerical simulations. After confirming the accuracy of the electric field models, I incorporated multi-scale modeling to further investigate how the externally induced electric fields alter the behavior of neurons and their subcellular activity. The subcellular modeling of neurons allows researchers to study the lasting effects of TMS in neurons in a sophisticated multi-scale model for the first time. In summary, the tools developed in my PhD can facilitate answering long-lasting questions about the TMS mechanism of action. This, in turn, will enable developing more effective TMS protocols/equipment which can lead to improved clinical outcomes in the treatment of psychiatric and neurological disorders with TMS.
Subjects/Keywords: Closed-loop TMS-EEG; Electric field modeling; multi-scale modeling; Transcranial Magnetic Stimulation
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Shirinpour, S. (2020). Tools for Improving and Understanding Transcranial Magnetic Stimulation. (Doctoral Dissertation). University of Minnesota. Retrieved from http://hdl.handle.net/11299/217801
Chicago Manual of Style (16th Edition):
Shirinpour, Seyedsina. “Tools for Improving and Understanding Transcranial Magnetic Stimulation.” 2020. Doctoral Dissertation, University of Minnesota. Accessed March 05, 2021.
http://hdl.handle.net/11299/217801.
MLA Handbook (7th Edition):
Shirinpour, Seyedsina. “Tools for Improving and Understanding Transcranial Magnetic Stimulation.” 2020. Web. 05 Mar 2021.
Vancouver:
Shirinpour S. Tools for Improving and Understanding Transcranial Magnetic Stimulation. [Internet] [Doctoral dissertation]. University of Minnesota; 2020. [cited 2021 Mar 05].
Available from: http://hdl.handle.net/11299/217801.
Council of Science Editors:
Shirinpour S. Tools for Improving and Understanding Transcranial Magnetic Stimulation. [Doctoral Dissertation]. University of Minnesota; 2020. Available from: http://hdl.handle.net/11299/217801

Dalhousie University
13.
Chevalier, Thrse.
Understanding Cortical Activation Associated with Second
Language Acquisition.
Degree: PhD, Department of Psychology and Neuroscience, 2014, Dalhousie University
URL: http://hdl.handle.net/10222/54054
► Repetitive transcranial magnetic stimulation (rTMS) performed at a low frequency has been found to have an inhibitory effect on cortical function, which may result in…
(more)
▼ Repetitive
transcranial magnetic stimulation (rTMS)
performed at a low frequency has been found to have an inhibitory
effect on cortical function, which may result in behavioural
consequences. Accordingly, rTMS may provide a valid model of focal
cortical lesions, such as stroke, in healthy individuals. rTMS has
been further proposed as a tool to inhibit high levels of cortical
activity in individuals with aphasia in right hemisphere (RH)
language homologues following a stroke that damages primary
language regions. It is thought that while RH activity is
compensatory during the early stages of recovery from stroke, it is
maladaptive in terms of long-term recovery. RH activity has also
been reported in healthy, low-proficiency bilinguals during second
language (L2) production; thus, it has been proposed that RH
activity may be better classified as reflecting effortful language
production. Furthermore, given similarities in RH activity during
language production in low-proficiency bilinguals and aphasics,
non-disabled controls learning an L2 may provide a useful analogue
to study aphasia. The research presented in this dissertation
examines learning of Spanish as an L2 in unilingual, English
speaking adults in an attempt to understand which brain regions are
associated with L2 acquisition, and the role that the RH plays in
language functioning. Results of this project indicate that adults
were able to learn novel Spanish vocabulary through a
computer-based language-training program, but that learning was
partially dependent on age and information processing capabilities.
Unlike previous research that has demonstrated a more extensive
network for L2 production, including regions of the RH, we found a
less extensive network for Spanish than for English, although
English language production was associated with RH activity.
Furthermore, inhibitory rTMS produced no effects on lexical
retrieval in either English or Spanish, indicating that the virtual
lesion induced by
TMS is not sufficient to mimic an aphasic stroke.
Overall, our results indicate that while the RH does play an
important role in language production, that role may differ between
healthy and aphasic individuals. Also, neither L2 acquisition nor
virtually induced lesions via
TMS appear to provide an ideal model
of post-stroke aphasia.
Advisors/Committee Members: Dr. Denise Klein (external-examiner), Dr. Gail Eskes (graduate-coordinator), Dr. Shaun Boe (thesis-reader), Dr. Gail Eskes (thesis-reader), Dr. Aaron Newman (thesis-supervisor), Received (ethics-approval), Not Applicable (manuscripts), Not Applicable (copyright-release).
Subjects/Keywords: Aphasia; Language; Second Language Acquisition; Functional Magnetic Resonance Imaging (fMRI); Transcranial Magnetic Stimulation (TMS); Theta Burst Stimulation (TBS)
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Chevalier, T. (2014). Understanding Cortical Activation Associated with Second
Language Acquisition. (Doctoral Dissertation). Dalhousie University. Retrieved from http://hdl.handle.net/10222/54054
Chicago Manual of Style (16th Edition):
Chevalier, Thrse. “Understanding Cortical Activation Associated with Second
Language Acquisition.” 2014. Doctoral Dissertation, Dalhousie University. Accessed March 05, 2021.
http://hdl.handle.net/10222/54054.
MLA Handbook (7th Edition):
Chevalier, Thrse. “Understanding Cortical Activation Associated with Second
Language Acquisition.” 2014. Web. 05 Mar 2021.
Vancouver:
Chevalier T. Understanding Cortical Activation Associated with Second
Language Acquisition. [Internet] [Doctoral dissertation]. Dalhousie University; 2014. [cited 2021 Mar 05].
Available from: http://hdl.handle.net/10222/54054.
Council of Science Editors:
Chevalier T. Understanding Cortical Activation Associated with Second
Language Acquisition. [Doctoral Dissertation]. Dalhousie University; 2014. Available from: http://hdl.handle.net/10222/54054

University of Bradford
14.
Strong, Samantha Louise.
The functional dissection of motion processing pathways in the human visual cortex using fMRI-guided TMS.
Degree: PhD, 2015, University of Bradford
URL: http://hdl.handle.net/10454/14426
► Motion-selectivity in human visual cortex comprises a number of different cortical loci including V1, V2, V3A, V3B, hV5/MT+ and V6 (Wandell et al., 2007). This…
(more)
▼ Motion-selectivity in human visual cortex comprises a number of different cortical loci including V1, V2, V3A, V3B, hV5/MT+ and V6 (Wandell et al., 2007). This thesis sought to investigate the specific functions of V3A and sub-divisions of hV5/MT+ (TO-1 and TO-2) by using transcranial magnetic stimulation (TMS) to transiently disrupt cortical activations within these areas during psychophysical tasks of motion perception. The tasks were chosen to coincide with previous non-human primate and human neuroimaging literature; translational, radial and rotational direction discrimination tasks and identification of the position of a focus of expansion. These results assert that TO-1 and TO-2 are functionally distinct subdivisions of hV5/MT+, as we have shown that both TO-1 and TO-2 are responsible for processing translational motion direction whilst only TO-2 is responsible for processing radial motion direction. In ipsilateral space, it was found that TO-1 and TO-2 both contribute to the processing of ipsilateral translational motion. Taken in a wider context, further results also suggested that these areas may form part of a network of cortical areas contributing to perception of self-motion (heading/egomotion), as TO-2 was not found to be responsible for processing the position of the central focus of expansion (imperative for self-direction). Instead, area V3A has been implicated as functionally responsible for processing this attribute of vision. Overall it is clear that TO-1, TO-2 and V3A have specific, distinct functions that contribute towards both parallel and serial motion processing pathways within the human brain.
Subjects/Keywords: 612.8; V5/MT; Function; TO-1; TO-2; Motion perception; V3A; Functional magnetic resonance imaging (fMRI); Transcranial magnetic stimulation (TMS)
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Strong, S. L. (2015). The functional dissection of motion processing pathways in the human visual cortex using fMRI-guided TMS. (Doctoral Dissertation). University of Bradford. Retrieved from http://hdl.handle.net/10454/14426
Chicago Manual of Style (16th Edition):
Strong, Samantha Louise. “The functional dissection of motion processing pathways in the human visual cortex using fMRI-guided TMS.” 2015. Doctoral Dissertation, University of Bradford. Accessed March 05, 2021.
http://hdl.handle.net/10454/14426.
MLA Handbook (7th Edition):
Strong, Samantha Louise. “The functional dissection of motion processing pathways in the human visual cortex using fMRI-guided TMS.” 2015. Web. 05 Mar 2021.
Vancouver:
Strong SL. The functional dissection of motion processing pathways in the human visual cortex using fMRI-guided TMS. [Internet] [Doctoral dissertation]. University of Bradford; 2015. [cited 2021 Mar 05].
Available from: http://hdl.handle.net/10454/14426.
Council of Science Editors:
Strong SL. The functional dissection of motion processing pathways in the human visual cortex using fMRI-guided TMS. [Doctoral Dissertation]. University of Bradford; 2015. Available from: http://hdl.handle.net/10454/14426

Tulane University
15.
Readus, Xavier N.
Auditory processing and motor systems: EEG analysis of cortical field potentials.
Degree: 2013, Tulane University
URL: https://digitallibrary.tulane.edu/islandora/object/tulane:27304
► Contemporary research has been examining potential links existing among sensory, motor and attentional systems. Previous studies using TMS have shown that the abrupt onset of…
(more)
▼ Contemporary research has been examining potential links existing among sensory, motor and attentional systems. Previous studies using TMS have shown that the abrupt onset of sounds can both capture attention and modulate motor cortex excitability, which may reflect the potential need for a behavioral response to the attended event. TMS, however, only quantifies motor cortex excitability immediately following the deliverance of a TMS pulse. Therefore, the temporal development of how the motor cortex is modulated by sounds can’t be quantified using TMS. Thus, the purpose of the present study is to use time frequency analysis of EEG to identify the time course of cortical mechanisms underlying increased motor cortex excitability after sound onset. Subjects sat in a sound attenuated booth with their hands outstretched at 45-degree angles while frequency modulated sounds were intermittently presented from a speaker either in the left and right hemispace. Our results indicated a transient reduction in EEG power from 18-24 Hz (300-600 ms latency) and then a long lasting increase in EEG power that began at ~800 ms and continued until at least 1.7 sec. The latency of EEG power changes was shorter for sounds presented from the right speaker at both time periods. When sounds were presented from the right speaker the contralateral hemisphere over motor regions also showed greater power increases after 800 ms relative to the ipsilateral hemisphere. In addition, power increases were greater in the left-handed subjects (8-12 Hz). Results showed that sounds increased EEG power at the time of a previously observed increase in motor cortex excitability. Findings also suggest an increased attentional salience to the right hemispace in neurologically normal subjects and asymmetrical hemispheric activations in right and left-handers.
Advisors/Committee Members: Golob, Edward (Thesis advisor).
Subjects/Keywords: Electroencephalography(EEG); Transcranial Magnetic Stimulation (TMS); Event-related Desynchronization (ERD)/Event-related Synchronization (ERS); School of Science & Engineering; Neuroscience; Masters
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APA (6th Edition):
Readus, X. N. (2013). Auditory processing and motor systems: EEG analysis of cortical field potentials. (Masters Thesis). Tulane University. Retrieved from https://digitallibrary.tulane.edu/islandora/object/tulane:27304
Chicago Manual of Style (16th Edition):
Readus, Xavier N. “Auditory processing and motor systems: EEG analysis of cortical field potentials.” 2013. Masters Thesis, Tulane University. Accessed March 05, 2021.
https://digitallibrary.tulane.edu/islandora/object/tulane:27304.
MLA Handbook (7th Edition):
Readus, Xavier N. “Auditory processing and motor systems: EEG analysis of cortical field potentials.” 2013. Web. 05 Mar 2021.
Vancouver:
Readus XN. Auditory processing and motor systems: EEG analysis of cortical field potentials. [Internet] [Masters thesis]. Tulane University; 2013. [cited 2021 Mar 05].
Available from: https://digitallibrary.tulane.edu/islandora/object/tulane:27304.
Council of Science Editors:
Readus XN. Auditory processing and motor systems: EEG analysis of cortical field potentials. [Masters Thesis]. Tulane University; 2013. Available from: https://digitallibrary.tulane.edu/islandora/object/tulane:27304
16.
Hogan, Adele Cherise.
Distortions in predicted motion: Pitch and direction influence imagined speed for a visual object during occlusion.
Degree: 2015, Victoria University of Wellington
URL: http://hdl.handle.net/10063/4708
► Visual motion prediction is essential for making key judgements about objects in the environment. These judgements are typically investigated using a time-to-contact (TTC) task, in…
(more)
▼ Visual motion prediction is essential for making key judgements about objects in the environment. These judgements are typically investigated using a time-to-contact (TTC) task, in which an object travels along a straight trajectory and disappears behind an occluder. Participants make a response coinciding with the moment the object would have contacted a visual landmark. The assumption is that the motion continues behind the occluder. This task is used to measure how we perceive and predict the arrival-time of objects. The addition of sound to TTC tasks generally enhances visual judgements. One characteristic which may affect how sound influences visual motion judgements is pitch. A rising pitch is associated with speeded motion and a falling pitch with slowed motion. Pitch change could therefore lead to biases in visual motion judgements; however, this has not yet been investigated. Furthermore, TTC tasks can utilise horizontal or vertical motion. In vertical motion, an additional variable that may be critical for TTC estimations is gravity. It is postulated that humans possess an internal model of gravity that allows us to make accurate predictions for downward motion. This model assumes faster downward than upward motion. However, this model can be wrongfully applied in constant speed tasks, producing faster speed estimations for downward stimuli when there is no acceleration. Therefore, vertical motion could lead to additional biases in visual motion judgements.
This thesis investigated whether pitch and gravity could affect the imagined speed of an object under occlusion. Specifically, a rising pitch was hypothesised to produce speeded predicted motion and falling pitch, slowed predicted motion. I investigated the influence of pitch change in vertical and horizontal planes. I also investigated two different aspects of pitch change, since dynamic pitch is a novel addition to TTC paradigms. Experiment 1A explored gradual pitch change and Experiment 1B used sudden pitch change. The hypothesised pitch effects were observed for a gradual, but not a sudden pitch change. However, a gravity effect was observed across both Experiments 1A and 1B, suggesting the presence of sound does not moderate this effect.
I also examined the cortical substrates of the audio-visual TTC task components by using
transcranial magnetic stimulation (
TMS) in Experiment 2. The superior temporal sulcus (STS) was targeted in this experiment, as it has been implicated in audio-visual integration.
TMS causes neuronal inhibition, and as such, can be used to determine whether an area is involved in a task. If the STS is responsible for audio-visual integration in a TTC task, then
TMS to the STS should disrupt the pitch effects evidenced in Experiment 1A. That is, a change in pitch should have no effect on TTC judgements compared to a constant tone. This result was evident only for rising tones, suggesting the involvement of the STS in the generating speeded predicted motion. The pitch effects observed in Experiment 1A and Experiment 2 implicate…
Advisors/Committee Members: Grimshaw, Gina.
Subjects/Keywords: Predicted motion; TMS; Transcranial magnetic stimulation; Pitch
…magnetic stimulation (TMS) to further our
understanding of the neural systems that… …x29;.
A technique that can be used to infer causation is transcranial magnetic
stimulation… …TMS Results ____________________________________ 61
Localisation of Stimulation Site… …x29;. The magnetic field creates a current in the cortical area of
stimulation, which… …TMS to the STS on Predicted Motion __________ 43
Method…
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Hogan, A. C. (2015). Distortions in predicted motion: Pitch and direction influence imagined speed for a visual object during occlusion. (Masters Thesis). Victoria University of Wellington. Retrieved from http://hdl.handle.net/10063/4708
Chicago Manual of Style (16th Edition):
Hogan, Adele Cherise. “Distortions in predicted motion: Pitch and direction influence imagined speed for a visual object during occlusion.” 2015. Masters Thesis, Victoria University of Wellington. Accessed March 05, 2021.
http://hdl.handle.net/10063/4708.
MLA Handbook (7th Edition):
Hogan, Adele Cherise. “Distortions in predicted motion: Pitch and direction influence imagined speed for a visual object during occlusion.” 2015. Web. 05 Mar 2021.
Vancouver:
Hogan AC. Distortions in predicted motion: Pitch and direction influence imagined speed for a visual object during occlusion. [Internet] [Masters thesis]. Victoria University of Wellington; 2015. [cited 2021 Mar 05].
Available from: http://hdl.handle.net/10063/4708.
Council of Science Editors:
Hogan AC. Distortions in predicted motion: Pitch and direction influence imagined speed for a visual object during occlusion. [Masters Thesis]. Victoria University of Wellington; 2015. Available from: http://hdl.handle.net/10063/4708

Freie Universität Berlin
17.
Volz, Magdalena Sarah.
The role of the motor cortex on pain modulation.
Degree: 2013, Freie Universität Berlin
URL: http://dx.doi.org/10.17169/refubium-8179
► Background: It is know that non-invasive peripheral and central stimulation techniques, such as transcutaneous electrical nerve stimulation, transcranial direct current stimulation and repetitive transcranial magnetic…
(more)
▼ Background: It is know that non-invasive peripheral and central
stimulation
techniques, such as transcutaneous electrical nerve
stimulation,
transcranial
direct current
stimulation and repetitive
transcranial magnetic stimulation,
can reduce the perception of pain. This could be shown in both chronic pain
patients and healthy subjects. The exact mechanisms underlying
stimulation
techniques remain unclear. However, it was found that the application over the
motor cortex revealed most promising results. The role of the motor cortex and
the increased excitability remain to be investigated. Hypotheses: The aim of
the study was to investigate the role of the motor cortex on pain modulation.
Therefore, we tested the effects of different motor, somatosensory and motor-
observation tasks executed by healthy volunteers. We evaluated the effects on
behavioral (pressure pain threshold) and neurophysiological (motor cortical
excitability via
transcranial magnetic stimulation (
TMS)) outcomes. Methods:
The study was conducted in a randomized, blinded and controlled (placebo-
tasks) manner. Within three experiments (A-C) a total number of 85 male,
right-handed, healthy volunteers were enrolled. All study visits comprised the
same assessments except the intervention tasks differed among the experiments,
which was accomplished with subjects’ left hand: A. 15 volunteers performed
three different motor tasks including motor learning with and without visual
feedback as well as simple hand movements (cross-over design); B. 40
volunteers completed either a somatosensory tasks with or without visual
feedback or a task with simple somatosensory input or a placebo-task including
no somatosensory demand, respectively (parallel design); C. 30 volunteers
performed either a motor-observation task (hand movements) or a placebo-task
(movement of geometrical figures) (parallel design). The study involved the
assessment of pressure pain threshold of both hands and the evaluation of
cortical excitability via
TMS (resting motor threshold (RMT), motor evoked
potential (MEP), intracortical facilitation (ICF), short intracortical
inhibition (SICI), and cortical silent period (CSP)). Data analyses included
ANOVAs of pain thresholds and
TMS-assessments as well as post-hoc t-tests.
Results: The tasks tested induced hand-specific effects. They showed a
significant increase in pressure pain threshold of the left target hand, which
reflects a reduced perception of pain. In contrast, pressure pain threshold
significantly decreased in the right hand indicating elevated pain perception.
Placebo-tasks remained unchanged. ANOVA of
TMS-assessments showed a
significant difference among the three motor tasks. Only the task with simple
hand movements significantly increased motor-cortical excitability, whereas
the motor learning tasks did not. The observation of hand movements also
resulted in significantly increased cortical excitability. In contrast,
somatosensory tasks significantly reduced cortical excitability.
Discussion/Significance: All motor tasks similarly…
Advisors/Committee Members: [email protected] (contact), w (gender), Herr Prof. Dr. med. F. Bermpohl (firstReferee), Herr Prof. Dr. med. J. Kuhn (furtherReferee), Herr Prof. Dr. med. M. Nitsche (furtherReferee).
Subjects/Keywords: motor cortex; transcranial magnetic stimulation; TMS; pain; 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Volz, M. S. (2013). The role of the motor cortex on pain modulation. (Thesis). Freie Universität Berlin. Retrieved from http://dx.doi.org/10.17169/refubium-8179
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Volz, Magdalena Sarah. “The role of the motor cortex on pain modulation.” 2013. Thesis, Freie Universität Berlin. Accessed March 05, 2021.
http://dx.doi.org/10.17169/refubium-8179.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Volz, Magdalena Sarah. “The role of the motor cortex on pain modulation.” 2013. Web. 05 Mar 2021.
Vancouver:
Volz MS. The role of the motor cortex on pain modulation. [Internet] [Thesis]. Freie Universität Berlin; 2013. [cited 2021 Mar 05].
Available from: http://dx.doi.org/10.17169/refubium-8179.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Volz MS. The role of the motor cortex on pain modulation. [Thesis]. Freie Universität Berlin; 2013. Available from: http://dx.doi.org/10.17169/refubium-8179
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Freie Universität Berlin
18.
Picht, Thomas.
Navigated transcranial magnetic stimulation for planning neurosurgical
procedures in motor eloquent brain regions.
Degree: 2016, Freie Universität Berlin
URL: http://dx.doi.org/10.17169/refubium-11024
The introduction of navigated transcranial magnetic stimulation into
neurosurgical practice has led to improvement of treatment quality in patients
suffering from brain tumors in motor eloquent areas.
Advisors/Committee Members: [email protected] (contact), m (gender), Prof. U. Sure (firstReferee), Prof. C. Strauss (furtherReferee).
Subjects/Keywords: TMS; brain tumor; functional mapping; eloquent brain; transcranial magnetic stimulation; motor mapping; 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Picht, T. (2016). Navigated transcranial magnetic stimulation for planning neurosurgical
procedures in motor eloquent brain regions. (Thesis). Freie Universität Berlin. Retrieved from http://dx.doi.org/10.17169/refubium-11024
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Picht, Thomas. “Navigated transcranial magnetic stimulation for planning neurosurgical
procedures in motor eloquent brain regions.” 2016. Thesis, Freie Universität Berlin. Accessed March 05, 2021.
http://dx.doi.org/10.17169/refubium-11024.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Picht, Thomas. “Navigated transcranial magnetic stimulation for planning neurosurgical
procedures in motor eloquent brain regions.” 2016. Web. 05 Mar 2021.
Vancouver:
Picht T. Navigated transcranial magnetic stimulation for planning neurosurgical
procedures in motor eloquent brain regions. [Internet] [Thesis]. Freie Universität Berlin; 2016. [cited 2021 Mar 05].
Available from: http://dx.doi.org/10.17169/refubium-11024.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Picht T. Navigated transcranial magnetic stimulation for planning neurosurgical
procedures in motor eloquent brain regions. [Thesis]. Freie Universität Berlin; 2016. Available from: http://dx.doi.org/10.17169/refubium-11024
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Canterbury
19.
Al-Toubi, Aamir Khamis Khalfan.
The role of the primary motor cortex (M1) in volitional and reflexive pharyngeal swallowing.
Degree: PhD, Speech and Language Sciences, 2013, University of Canterbury
URL: http://dx.doi.org/10.26021/8770
► Background and aims: The primary motor cortex (M1) controls voluntary motor behaviours. M1 has been identified to play a major role in the execution of…
(more)
▼ Background and aims:
The primary motor cortex (M1) controls voluntary motor behaviours. M1 has been identified to play a major role in the execution of voluntary corticospinal tasks as well as self-initiated corticobulbar tasks. However, the involvement of M1 in more complex corticubulbar tasks, such as swallowing, is not yet fully understood. Swallowing is quite different from other voluntary motor tasks as it has both voluntary and reflexive components. The degree of M1 involvement in the pharyngeal, or more reflexive, component of swallowing is unclear. Studies investigating the role of M1 in swallowing have yielded contradictory findings regarding the specific functional contribution of M1 to swallowing. Therefore, further investigation is warranted to clarify the role of M1 in pharyngeal swallowing.
Discrete saliva or water swallowing has been utilized in most studies investigating neurophysiology of swallowing in health and disease. However, individuals most frequently complete multiple, consecutive swallows during the ingestion of liquid. Biomechanical differences between discrete and continuous water swallows have been identified using videofluoroscopic swallowing study (VFSS). However, no studies have investigated the pharyngeal pressure differences between these two swallowing tasks. Additional insights into task differences may be revealed through evaluation of pharyngeal pressure utilizing pharyngeal manometry.
This research programme sought to clarify the role of M1 in reflexively and volitionally initiated pharyngeal swallowing. In order to understand M1 involvement in the execution of swallowing, comparative tasks that require known dependence on M1 were also included in this research programme. This research programme addressed the biomechanical changes in motor behaviours as a result of neural disruption during the performance of a number of motor tasks. This neural disruption was intrinsically generated through application of dual task (DT) paradigm and extrinsically generated using single pulse transcranial magnetic stimulation (TMS). A secondary aim of this research programme was to identify the differences in pharyngeal pressure generation between discrete and continuous swallowing.
Methods:
Twenty-four right handed participants (12 males, average age= 24.4, SD= 6.3) were recruited to this research programme. A number of motor tasks that vary in complexity were tested. These tasks included: volitional swallowing, reflexive swallowing, eyebrow movement, jaw movement and finger tapping with right, left, or bilateral index fingers.
Participants performed multiple trials of several tasks in each study. Repetitions of tasks during a single session may affect performance due to factors such as fatigue or practice. A baseline study was undertaken to determine within-participant variability of measures across repeated trials.
Following the baseline study, the role of M1 in pharyngeal swallowing was investigated in two main studies in counter balanced order. The role of M1 in…
Subjects/Keywords: Primary motor cortex (M1); Corticobulbar pathways; Corticospinal pathways; Dual-task paradigm; Transcranial magnetic stimulation (TMS); Volitional swallowing; Reflexive swallowing
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Al-Toubi, A. K. K. (2013). The role of the primary motor cortex (M1) in volitional and reflexive pharyngeal swallowing. (Doctoral Dissertation). University of Canterbury. Retrieved from http://dx.doi.org/10.26021/8770
Chicago Manual of Style (16th Edition):
Al-Toubi, Aamir Khamis Khalfan. “The role of the primary motor cortex (M1) in volitional and reflexive pharyngeal swallowing.” 2013. Doctoral Dissertation, University of Canterbury. Accessed March 05, 2021.
http://dx.doi.org/10.26021/8770.
MLA Handbook (7th Edition):
Al-Toubi, Aamir Khamis Khalfan. “The role of the primary motor cortex (M1) in volitional and reflexive pharyngeal swallowing.” 2013. Web. 05 Mar 2021.
Vancouver:
Al-Toubi AKK. The role of the primary motor cortex (M1) in volitional and reflexive pharyngeal swallowing. [Internet] [Doctoral dissertation]. University of Canterbury; 2013. [cited 2021 Mar 05].
Available from: http://dx.doi.org/10.26021/8770.
Council of Science Editors:
Al-Toubi AKK. The role of the primary motor cortex (M1) in volitional and reflexive pharyngeal swallowing. [Doctoral Dissertation]. University of Canterbury; 2013. Available from: http://dx.doi.org/10.26021/8770

University of Minnesota
20.
Cline, Christopher.
Noninvasive Neuroimaging Of Responses To Transcranial Magnetic Stimulation.
Degree: PhD, Biomedical Engineering, 2018, University of Minnesota
URL: http://hdl.handle.net/11299/215134
► Transcranial magnetic stimulation (TMS) and electroencephalography (EEG) provide means to noninvasively measure and modulate activity in the brain. EEG has the potential to infer user…
(more)
▼ Transcranial magnetic stimulation (TMS) and electroencephalography (EEG) provide means to noninvasively measure and modulate activity in the brain. EEG has the potential to infer user intent from measured signals, making it possible to build brain-computer interfaces for augmentative and alternative communication and control of devices that do not rely on intact motor function. TMS offers the ability to transiently perturb neural activity with good temporal and spatial precision, and to modulate longer-term excitability and network function, with various applications in both neuroscientific research and clinical treatment. However, both EEG and TMS have limitations, due in a large part to their noninvasiveness. EEG-based BCIs face issues with inconsistent inference of intent estimated from low-SNR measurements, which degrades the speed and accuracy of BCI control. Likewise, current TMS approaches face issues with variability in responses to stimulation, based on lack of precise targeting information and knowledge of underlying mechanisms of stimulation effects, resulting in inefficient or inconsistently effective clinical neuromodulation interventions. In this work, I describe several efforts to address these issues using approaches combining TMS and EEG. To improve our understanding of factors influencing successful motor imagery based BCI control, I applied TMS targeted at perturbing specific neural circuits and measuring resulting changes in BCI control. Conversely, I also explored factors influencing responses to TMS and how EEG can be used to inform stimulation via measurements of stimulation response and estimation of pre-stimulation brain state.
Subjects/Keywords: electroencephalography; neuroimaging; transcranial magnetic stimulation
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Cline, C. (2018). Noninvasive Neuroimaging Of Responses To Transcranial Magnetic Stimulation. (Doctoral Dissertation). University of Minnesota. Retrieved from http://hdl.handle.net/11299/215134
Chicago Manual of Style (16th Edition):
Cline, Christopher. “Noninvasive Neuroimaging Of Responses To Transcranial Magnetic Stimulation.” 2018. Doctoral Dissertation, University of Minnesota. Accessed March 05, 2021.
http://hdl.handle.net/11299/215134.
MLA Handbook (7th Edition):
Cline, Christopher. “Noninvasive Neuroimaging Of Responses To Transcranial Magnetic Stimulation.” 2018. Web. 05 Mar 2021.
Vancouver:
Cline C. Noninvasive Neuroimaging Of Responses To Transcranial Magnetic Stimulation. [Internet] [Doctoral dissertation]. University of Minnesota; 2018. [cited 2021 Mar 05].
Available from: http://hdl.handle.net/11299/215134.
Council of Science Editors:
Cline C. Noninvasive Neuroimaging Of Responses To Transcranial Magnetic Stimulation. [Doctoral Dissertation]. University of Minnesota; 2018. Available from: http://hdl.handle.net/11299/215134

University of Stirling
21.
Nikolaou, Zacharias.
Electrophysiological and SCAT 5 characteristics of contact vs non-contact sport athletes.
Degree: M. Phil., 2018, University of Stirling
URL: http://hdl.handle.net/1893/28342
► Introduction: There are a number of studies and systematic reviews suggesting potential chronic neurodegenerative effects of repetitive subconcussive head impacts. Indeed, most neuroimaging and some…
(more)
▼ Introduction: There are a number of studies and systematic reviews suggesting potential chronic neurodegenerative effects of repetitive subconcussive head impacts. Indeed, most neuroimaging and some serum biomarker tests used in the literature generally present consistent evidence for negative effects of repetitive subconcussive head impacts. However, these tests have limited utility as side-line diagnostic tests. Purpose: Investigate whether two prospective side-line tests, sport concussion assessment tool 5 (SCAT 5) and transcranial magnetic stimulation (TMS), have enough sensitivity to detect relatively small and transient electrophysiological and cognitive changes in American football players who are very prone to repetitive subconcussive head impacts. The primary aim of this study is to investigate the effects of subconcussive head impacts on TMS and SCAT 5 performance by comparing contact with non-contact sport athletes. The secondary aim is to investigate the reproducibility and reliability of TMS and SCAT 5 in contact sport athletes. Methods: For the first section of the study, we assessed TMS and SCAT 5 measures on seventeen American football players (mean ±SD age: 23 ±7 years) and seventeen non-contact sport participants (mean ±SD age: 24 ±3 years) who were recruited for only one session. To assess the day-to-day reliability of each measure, the seventeen American football players were tested for a second time at least seven days following the first session. Results: Compared to the TMS day-to-day reliability analysis, SCAT 5 test scores presented poorer reproducibility and higher coefficients of variation (4–6% vs 10–66%, respectively). There were no significant differences in SCAT 5 test scores and corticospinal-silent period between contact and non-contact sport players. Conclusion: This is the first study to demonstrate similar electrophysiological and SCAT 5 characteristics between American football players and non-contact sport athletes. Also the electrophysiological changes observed are supported by our highly reliable and reproducible inter-day TMS data.
Subjects/Keywords: TMS; Transcranial Magnetic Stimulation; Corticospinal silent period; SCAT5; Electrophysiological changes; Neurocognitive assessment; Brain – Concussion; Brain Injury – Evaluation; Magnetic brain stimulation; Football players – Health and hygiene
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Nikolaou, Z. (2018). Electrophysiological and SCAT 5 characteristics of contact vs non-contact sport athletes. (Masters Thesis). University of Stirling. Retrieved from http://hdl.handle.net/1893/28342
Chicago Manual of Style (16th Edition):
Nikolaou, Zacharias. “Electrophysiological and SCAT 5 characteristics of contact vs non-contact sport athletes.” 2018. Masters Thesis, University of Stirling. Accessed March 05, 2021.
http://hdl.handle.net/1893/28342.
MLA Handbook (7th Edition):
Nikolaou, Zacharias. “Electrophysiological and SCAT 5 characteristics of contact vs non-contact sport athletes.” 2018. Web. 05 Mar 2021.
Vancouver:
Nikolaou Z. Electrophysiological and SCAT 5 characteristics of contact vs non-contact sport athletes. [Internet] [Masters thesis]. University of Stirling; 2018. [cited 2021 Mar 05].
Available from: http://hdl.handle.net/1893/28342.
Council of Science Editors:
Nikolaou Z. Electrophysiological and SCAT 5 characteristics of contact vs non-contact sport athletes. [Masters Thesis]. University of Stirling; 2018. Available from: http://hdl.handle.net/1893/28342

University of Southern California
22.
Qi, Feng.
Computational transcranial magnetic stimulation
(TMS).
Degree: PhD, Neuroscience, 2010, University of Southern California
URL: http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll127/id/332750/rec/1554
► Transcranial Magnetic Stimulation (TMS) is a noninvasive brain stimulation technique that is increasingly used in clinical neuroscience research. Since the invention of TMS in 1985,…
(more)
▼ Transcranial Magnetic Stimulation (
TMS) is a
noninvasive brain
stimulation technique that is increasingly used
in clinical neuroscience research. Since the invention of
TMS in
1985, new applications and
stimulation patterns for this technique
have been developed and advanced very fast. However, compared with
other research techniques used in neuroscience, the use of
computational tools for
TMS is limited. The studies introduced in
this thesis applied computational methods adapted from the field of
machine learning to
TMS experimental procedures and data analysis,
and inspired the idea of computational
TMS. These studies showed
that computational
TMS improved the accuracy and efficiency of
TMS,
and could be used to investigate neuroscience problems. In Chapter
1, the background, basic principles, and variations of
TMS
techniques are introduced, and the idea of computational
TMS is
motivated. Then three example computational
TMS studies are
demonstrated: Chapter 2 introduces a new protocol facilitating the
TMS motor threshold (MT) estimation. This protocol uses Bayesian
framework to incorporate prior knowledge of MT and is two to five
times faster than the fastest existing method. Chapter 3 introduces
a fast protocol for
TMS mapping. This protocol uses high-resolution
coordinate data obtained from a neuronavigation system and
non-parametric regression techniques to generate
TMS maps. Chapter
4 is a quantitative analysis of the relationship between Motor
Evoked Potential (MEP) and
TMS coil placement, which highlights the
importance of
TMS spatial information. This analysis also supports
the neurophysiology hypothesis that
TMS excites the column
structures on the anterior bank of central sulcus. Chapter 5
includes conclusion and future work of computational
TMS.
Advisors/Committee Members: Schweighofer, Nicolas (Committee Chair), Schaal, Stefan (Committee Member), Lu, Zhong-Lin (Committee Member), Sha, Fei (Committee Member).
Subjects/Keywords: transcranial magnetic stimulation; TMS; neuroscience; brain stimulation; motor cortex; machine learning; computation
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Qi, F. (2010). Computational transcranial magnetic stimulation
(TMS). (Doctoral Dissertation). University of Southern California. Retrieved from http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll127/id/332750/rec/1554
Chicago Manual of Style (16th Edition):
Qi, Feng. “Computational transcranial magnetic stimulation
(TMS).” 2010. Doctoral Dissertation, University of Southern California. Accessed March 05, 2021.
http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll127/id/332750/rec/1554.
MLA Handbook (7th Edition):
Qi, Feng. “Computational transcranial magnetic stimulation
(TMS).” 2010. Web. 05 Mar 2021.
Vancouver:
Qi F. Computational transcranial magnetic stimulation
(TMS). [Internet] [Doctoral dissertation]. University of Southern California; 2010. [cited 2021 Mar 05].
Available from: http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll127/id/332750/rec/1554.
Council of Science Editors:
Qi F. Computational transcranial magnetic stimulation
(TMS). [Doctoral Dissertation]. University of Southern California; 2010. Available from: http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll127/id/332750/rec/1554

University of Toledo
23.
Eley, Devon M.
Neuromuscular Measures in Female Patients with Knee
Osteoarthritis: A Pilot Study.
Degree: MS, Exercise Science, 2015, University of Toledo
URL: http://rave.ohiolink.edu/etdc/view?acc_num=toledo1430412150
► Context: Symptomatic knee osteoarthritis (OA) affects 12.1% of adults over the age of 60 in the United States, making OA the leading cause of disability…
(more)
▼ Context: Symptomatic knee osteoarthritis (OA) affects
12.1% of adults over the age of 60 in the United States, making OA
the leading cause of disability for older adults in the U.S. OA is
a degenerative disease characterized by joint space narrowing,
development of osteophytes, and articular cartilage degeneration.
Symptoms associated with knee OA include pain, loss of motion, and
decreased functional ability. These factors lead to disability,
decreased quality of life, and a higher risk of comorbidities
including obesity and cardiovascular disease. OA has been shown to
also affect voluntary quadriceps strength and activation, further
impairing function and quality of life. These neuromuscular
alterations affecting the injured joint are referred to as central
activation deficits (CAD). This affects the ability to activate
motor neurons around the joint for recruitment during normal
muscular contractions. This results in decreased muscle contraction
capabilities and becomes a problem when these deficits persist and
limit the ability to regain optimal muscle function. However, it is
not fully understood how these deficits contribute to and worsen
knee OA. Objective: To understand how knee OA influences quadriceps
strength and central activation. Additionally, we sought to
determine if a group-based exercise intervention could augment CAD
in women with knee OA. Design: Pilot investigation with an embedded
case series. Setting: Research laboratory. Methods: Baseline
demographics were recorded on all participants. Baseline MVIC and
CAR were measured using the burst superimposition technique.
Baseline
TMS measures (AMT, SICI, LICI, ICF) were calculated.
Participants completed the 8-week therapeutic exercise
intervention. Follow-up MVIC and CAR were recorded. Participants:
Nine patients (age=57.11±5.28, height=1.71±0.06m,
mass=90.52±22.58kg, BMI=30.81±6.69) completed baseline strength and
CAD measures. Three patients (age=59.67±2.89, height=1.70±0.00m,
mass=85.13±8.95kg, BMI=29.46±3.10) completed baseline strength and
CAD testing followed by the 8-week therapeutic exercise
intervention and follow-up testing. Results: At baseline,
quadriceps strength was 1.70±0.74 Nm/kg and CAR was 0.97±0.03.
TMS
measures at baseline were: AMT=46.50±7.85%, SICI=0.52±0.27,
ICF=2.17±0.97, and LICI=0.36±0.21.For the subset of women who
completed the intervention, strength decreased from baseline to
follow-up (2.22±0.83 Nm/kg and 1.67±0.67 Nm/kg, respectively),
while CAR remained relatively unchanged 0.99±0.01 and 0.97±0.03.
Conclusions: Results show similarities among
TMS between this and
other studies done on this type of patient population. Quadriceps
strength decreased after an 8-week therapeutic exercise
intervention, which is counterintuitive. Additional studies are
required to further understand the role of quadriceps central
activation in the osteoarthritic process so that appropriate
interventions can be developed and implemented.
Advisors/Committee Members: Donovan, Luke (Committee Chair).
Subjects/Keywords: Health; Health Care; Health Sciences; Knee osteoarthritis; knee OA; CAR; TMS; central activation ratio; transcranial magnetic stimulation; therapeutic exercise; rehabilitation; group therapy; women
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Eley, D. M. (2015). Neuromuscular Measures in Female Patients with Knee
Osteoarthritis: A Pilot Study. (Masters Thesis). University of Toledo. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=toledo1430412150
Chicago Manual of Style (16th Edition):
Eley, Devon M. “Neuromuscular Measures in Female Patients with Knee
Osteoarthritis: A Pilot Study.” 2015. Masters Thesis, University of Toledo. Accessed March 05, 2021.
http://rave.ohiolink.edu/etdc/view?acc_num=toledo1430412150.
MLA Handbook (7th Edition):
Eley, Devon M. “Neuromuscular Measures in Female Patients with Knee
Osteoarthritis: A Pilot Study.” 2015. Web. 05 Mar 2021.
Vancouver:
Eley DM. Neuromuscular Measures in Female Patients with Knee
Osteoarthritis: A Pilot Study. [Internet] [Masters thesis]. University of Toledo; 2015. [cited 2021 Mar 05].
Available from: http://rave.ohiolink.edu/etdc/view?acc_num=toledo1430412150.
Council of Science Editors:
Eley DM. Neuromuscular Measures in Female Patients with Knee
Osteoarthritis: A Pilot Study. [Masters Thesis]. University of Toledo; 2015. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=toledo1430412150

University of Sydney
24.
Chang, Florence.
Movement and postural control in dystonia
.
Degree: 2020, University of Sydney
URL: http://hdl.handle.net/2123/22982
► Recently separate control systems for postural and movement control have been found in primates. Dystonia is a hyperkinetic movement disorder and its cause it not…
(more)
▼ Recently separate control systems for postural and movement control have been found in primates. Dystonia is a hyperkinetic movement disorder and its cause it not well understood. We have observed that dystonia patients have preserved fine movement control, but difficulty maintaining the appropriate and sustained posture that supports these movements. Postural control requires multiple modalities of sensory input such as cutaneous, proprioceptive, vestibular and visual stimuli. Through clinical observation, dystonia is improved by sensory alteration. Sensorimotor integration dysfunction has been observed in dystonia patients using multiple methods of study, such as neuroimaging and neurophysiological studies. This thesis investigates if dystonia is secondary to abnormalities in postural control rather than movement control mechanisms, using transcranial magnetic stimulation (TMS) and surface electromyography (EMG). In order to understand how to interpret neurophysiological data collected from focal cervical dystonia patients, we analysed the clinical characteristics and demographics of focal cervical dystonia and writer’s cramp patients. We also compared our findings to the results from a larger cohort which was derived from Dystonia Coalition study, an international collaborative study, in which our participants contributed. Cervical dystonia patients are more likely to have associated tremor and a geste antagoniste than writer’s cramp patients, whereas task-specificity is more common in writer’s cramp. Cervical dystonia severity and pain scale had a strong positive correlation with cortical silent period, whereas the writer’s cramp severity scale had a strong negative correlation with cortical silent period. The differences in clinical characteristics and neurophysiological findings between focal cervical dystonia and writer’s cramp patients reflect differences in pathophysiology and neurophysiological studies of focal dystonia need to analyse dystonia subtypes separately. The differences in muscle activity generation and co-contraction of agonist and antagonist muscle groups were analysed in normal controls and focal dystonia patients during comparable movement and postural control tasks. It was hypothesized that during a postural control task, there would be an increase in agonist and antagonist co-contraction, which is a known neurophysiological correlate in dystonia. Using surface EMG, we found no increase in agonist/antagonist co-contraction during posture maintenance in dystonia patients, contrary to our hypothesis. However, during a non-dystonia inducing task, there was exaggerated compensatory postural muscle activity during the movement phase of voluntary wrist extension in both cervical dystonia and writer’s cramp patients. In order to explore differences in the behaviour of the motor cortex during postural versus movement control in healthy participants, transcranial magnetic stimulation was used to measure cortical excitability and inhibition. A novel paradigm was developed where participants…
Subjects/Keywords: dystonia;
posture;
movement;
transcranial magnetic stimulation
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Chang, F. (2020). Movement and postural control in dystonia
. (Thesis). University of Sydney. Retrieved from http://hdl.handle.net/2123/22982
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Chang, Florence. “Movement and postural control in dystonia
.” 2020. Thesis, University of Sydney. Accessed March 05, 2021.
http://hdl.handle.net/2123/22982.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Chang, Florence. “Movement and postural control in dystonia
.” 2020. Web. 05 Mar 2021.
Vancouver:
Chang F. Movement and postural control in dystonia
. [Internet] [Thesis]. University of Sydney; 2020. [cited 2021 Mar 05].
Available from: http://hdl.handle.net/2123/22982.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Chang F. Movement and postural control in dystonia
. [Thesis]. University of Sydney; 2020. Available from: http://hdl.handle.net/2123/22982
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Boston University
25.
Reddy, Vamsee.
Electromagnetic interventions as a therapeutic approach to spreading depression.
Degree: MS, Medical Sciences, 2017, Boston University
URL: http://hdl.handle.net/2144/23842
► Spreading depression (SD) is a slow propagating wave of depolarization that can spread throughout the cortex in the event of brain injury or any general…
(more)
▼ Spreading depression (SD) is a slow propagating wave of depolarization that can spread throughout the cortex in the event of brain injury or any general energy failure of the brain. Massive cellular depolarization causes enormous ionic and water shifts and silences synaptic transmission in the affected tissue. Large amounts of energy are required to restore ionic gradients and are not always met. When these energetic demands are not met, brain tissue damage can occur. The exact mechanism behind initiation and propagation of SD are unknown, but a general model is known. It may be possible to prevent or delay the onset of SD using non-invasive electromagnetic techniques. Transcranial magnetic stimulation (TMS), electrical stimulation (ES), and transcranial direct coupled stimulation (tDCS) could be used to decrease neuronal excitability in different ways. In theory, any technique that can reduce cortical excitability could suppress SD initiating or propagating.
Subjects/Keywords: Neurosciences; Cortical spreading depression; Repetitive transcranial magnetic stimulation; Spreading depression; Transcranial direct current stimulation; Transcranial magnetic stimulation
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Reddy, V. (2017). Electromagnetic interventions as a therapeutic approach to spreading depression. (Masters Thesis). Boston University. Retrieved from http://hdl.handle.net/2144/23842
Chicago Manual of Style (16th Edition):
Reddy, Vamsee. “Electromagnetic interventions as a therapeutic approach to spreading depression.” 2017. Masters Thesis, Boston University. Accessed March 05, 2021.
http://hdl.handle.net/2144/23842.
MLA Handbook (7th Edition):
Reddy, Vamsee. “Electromagnetic interventions as a therapeutic approach to spreading depression.” 2017. Web. 05 Mar 2021.
Vancouver:
Reddy V. Electromagnetic interventions as a therapeutic approach to spreading depression. [Internet] [Masters thesis]. Boston University; 2017. [cited 2021 Mar 05].
Available from: http://hdl.handle.net/2144/23842.
Council of Science Editors:
Reddy V. Electromagnetic interventions as a therapeutic approach to spreading depression. [Masters Thesis]. Boston University; 2017. Available from: http://hdl.handle.net/2144/23842
26.
S. D'Ambrosio.
SLEEPING WHILE AWAKE: A NEUROPHYSIOLOGICAL INVESTIGATION ON SLEEP DURING WAKEFULNESS.
Degree: 2020, Università degli Studi di Milano
URL: http://hdl.handle.net/2434/707369
► Il sonno e la veglia vengono comunemente considerati come due stati distinti. L’alternanza tra essi, la cui presenza è stata dimostrata in ogni specie animale…
(more)
▼ Il sonno e la veglia vengono comunemente considerati come due stati distinti. L’alternanza tra essi, la cui presenza è stata dimostrata in ogni specie animale studiata fino ad oggi, sembra essere una delle caratteristiche che definisce la nostra vita. Allo stesso tempo, però, le scoperte portate alla luce negli ultimi decenni hanno offuscato i confini tra questi due stati. I meccanismi del sonno hanno sempre affascinato i neurofisiologi, che infatti, nell’ultimo secolo, li hanno caratterizzati in dettaglio: ora sappiamo che all’attività del sonno sottostà una specifica attività neuronale chiamata slow oscillation. La slow oscillation, che è costituita da (ancora una volta) un’alternanza tra periodi di attività e periodi di iperpolarizzazione e silenzio neuronale (OFF-periods), è la modalità base di attivazione del cervello dormiente. Questa alternanza è dovuta alla tendenza dei neuroni surante lo stato di sonno, di passare ad un periodo silente dopo un’attivazione iniziale, una tendenza a cui viene dato il nome di bistabilità neuronale. Molti studi hanno dimostrato come la bistabilità neuronale tipica del sonno ed i relativi OFF-periods, possano accadere anche durante la veglia in particolari condizioni patologiche, nelle transizioni del sonno e durante le deprivazioni di sonno. Per questo motivo, se accettassimo che la bistabilità neuronale e gli OFF-periods rappresentino una caratteristica fondamentale del sonno, allora dovremmo ammettere che stiamo assistendo ad un cambio di paradigma: da una prospettiva neurofisiologica il sonno può intrudere nella veglia. In questa tesi ho analizzato i nuovi -fluidi- confini tra sonno e veglia e le possibili implicazioni di questi nel problema della persistenza personale attraverso il tempo. Inoltre, ho studiato le implicazioni cliniche dell’intrusione di sonno nella veglia in pazienti con lesioni cerebrali focali di natura ischemica. In particolare, i miei obiettivi sono stati: 1) Dimostrare come la bistabilità neuronale possa essere responsabile della perdita di funzione nei pazienti affetti da ischemia cerebrale e come questo potrebbe avere implicazioni nello studio della patofisiologia dell’ischemia cerebrale e nella sua terapia; 2) Stabilire le basi per un modello di sonno locale presente nella vita di tutti i giorni: la sensazione di sonnolenza. Infatti, essa potrebbe riflettere la presenza di porzioni di corteccia in stato di sonno, ma durante lo stato di veglia; 3) Difendere il criterio biologico di identità, che troverebbe nell’attività cerebrale la continuità necessaria al mantenimento della nostra identità nel tempo.
Sleep and wakefulness are considered two mutually exclusive states. The alternation between those two states seems to be a defining characteristic of our life, a ubiquitous phenomenon demonstrated in every animal species investigated so far. However, during the last decade, advances in neurophysiology have blurred the boundaries between those states. The mechanisms of sleep have always intrigued neurophysiologists and great advances have been made over…
Advisors/Committee Members: tutors: M. Massimini, S. Sarasso, coordinatore: A. Pinotti, MASSIMINI, MARCELLO, PINOTTI, ANDREA.
Subjects/Keywords: sleep; wakefulness; physiology; philosophy; OFF-periods; slow waves; down states; perturbations; identity; neurophysiology; electrophysiology; transcranial magnetic stimulation; electroencephalogram; TMS; EEG; TMS/EEG; philosophy of mind; philosophy of science; Settore M-FIL/02 - Logica e Filosofia della Scienza; Settore BIO/09 - Fisiologia
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
D'Ambrosio, S. (2020). SLEEPING WHILE AWAKE: A NEUROPHYSIOLOGICAL INVESTIGATION ON SLEEP DURING WAKEFULNESS. (Thesis). Università degli Studi di Milano. Retrieved from http://hdl.handle.net/2434/707369
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
D'Ambrosio, S.. “SLEEPING WHILE AWAKE: A NEUROPHYSIOLOGICAL INVESTIGATION ON SLEEP DURING WAKEFULNESS.” 2020. Thesis, Università degli Studi di Milano. Accessed March 05, 2021.
http://hdl.handle.net/2434/707369.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
D'Ambrosio, S.. “SLEEPING WHILE AWAKE: A NEUROPHYSIOLOGICAL INVESTIGATION ON SLEEP DURING WAKEFULNESS.” 2020. Web. 05 Mar 2021.
Vancouver:
D'Ambrosio S. SLEEPING WHILE AWAKE: A NEUROPHYSIOLOGICAL INVESTIGATION ON SLEEP DURING WAKEFULNESS. [Internet] [Thesis]. Università degli Studi di Milano; 2020. [cited 2021 Mar 05].
Available from: http://hdl.handle.net/2434/707369.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
D'Ambrosio S. SLEEPING WHILE AWAKE: A NEUROPHYSIOLOGICAL INVESTIGATION ON SLEEP DURING WAKEFULNESS. [Thesis]. Università degli Studi di Milano; 2020. Available from: http://hdl.handle.net/2434/707369
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Otago
27.
Harrington, Allanah.
Theta Burst Stimulation of the Human Cerebellum
.
Degree: University of Otago
URL: http://hdl.handle.net/10523/6009
► Background Repetitive Transcranial Magnetic Stimulation (rTMS) of the cerebral cortex has been previously applied as a non-invasive therapy for neurological conditions due to its potential…
(more)
▼ Background
Repetitive
Transcranial Magnetic Stimulation (rTMS) of the cerebral cortex has been previously applied as a non-invasive therapy for neurological conditions due to its potential to modify cortical excitability through neuroplasticity. Cerebellar
stimulation has the potential to modify cortical excitability because of its predominantly inhibitory connections with the motor cortex and other cortical areas. Previous studies have shown that cerebellar rTMS, including theta burst
stimulation (TBS) can modulate excitability in the motor cortex, but the findings have been variable. The aim of this study was to investigate the effects of 30Hz cerebellar TBS on motor evoked potentials (MEP) and
TMS-evoked cortical potentials (TEP).
Method
Combined
TMS and electroencephalography (
TMS-EEG) was carried out on 16 healthy participants, aged 21-30 years. Each
subject was studied in three separate sessions, in which 30Hz intermittent TBS (iTBS), continuous TBS (cTBS) or sham
stimulation at stimulus intensity of 80% or 90% of active motor threshold (AMT) was applied to the right cerebellar hemisphere. Each session consisted of active and resting MEP and TEP recording from the left motor cortex before and after TBS. EEG recordings were analysed offline using EEGLAB software and independent component analysis (ICA) was used to remove artifacts. TEP were extracted and averaged. Mean N100 waveform amplitudes were measured before and after each treatment protocol. Post
stimulation values for all parameters were compared using mixed model ANOVA, with pre-treatment values as covariates.
Results
The TBS protocol at 90% of AMT stimulus intensity produced a significant decrease in amplitude of the resting MEP after cTBS compared to sham TBS, F(2,13)= 4.87, p=0.035. Cortical silent period (CSP) was increased following iTBS, compared to sham, F(2,13)= 4.87, p=0.026. The effects of 80% TBS on MEP were not significant The mean N100 amplitude was significantly greater after iTBS than sham TBS using 80% or 90%
stimulation F(2,348)=197.80, p < 0.001 and F(2,455)=6.17, p = 0.02, respectively.
Conclusion
The study demonstrated that 30Hz cerebellar cTBS at 90% AMT produced a reduction in overall excitability of the contralateral motor cortex, as shown by reduced resting MEP amplitude. Although iTBS produced an increase in the CSP and the N100 amplitude, both thought to reflect intracortical inhibition, there was no significant effect of iTBS on MEP amplitude. As this measure is dependent on the net effect of inhibitory and facilitatory networks in the cerebral cortex, it is possible that an increase in intracortical inhibition cancelled out the inhibitory effects. These findings provide further evidence that cortical excitability can be modulated through cerebellar TBS. Cerebellar TBS has potential as a therapeutic modality for a number of neurological conditions where there is abnormal cortical excitability, including epilepsy, dystonia and Parkinson’s disease. Future investigation of its effects is required before it can be…
Advisors/Committee Members: Hammond-Tooke, Graeme (advisor).
Subjects/Keywords: Cerebellum;
Theta Burst Stimulation;
intracortical inhibition;
iTBS;
cTBS;
MEP;
TMS-EEG;
Repetitive Transcranial Magnetic Stimulation
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Harrington, A. (n.d.). Theta Burst Stimulation of the Human Cerebellum
. (Masters Thesis). University of Otago. Retrieved from http://hdl.handle.net/10523/6009
Note: this citation may be lacking information needed for this citation format:
No year of publication.
Chicago Manual of Style (16th Edition):
Harrington, Allanah. “Theta Burst Stimulation of the Human Cerebellum
.” Masters Thesis, University of Otago. Accessed March 05, 2021.
http://hdl.handle.net/10523/6009.
Note: this citation may be lacking information needed for this citation format:
No year of publication.
MLA Handbook (7th Edition):
Harrington, Allanah. “Theta Burst Stimulation of the Human Cerebellum
.” Web. 05 Mar 2021.
Note: this citation may be lacking information needed for this citation format:
No year of publication.
Vancouver:
Harrington A. Theta Burst Stimulation of the Human Cerebellum
. [Internet] [Masters thesis]. University of Otago; [cited 2021 Mar 05].
Available from: http://hdl.handle.net/10523/6009.
Note: this citation may be lacking information needed for this citation format:
No year of publication.
Council of Science Editors:
Harrington A. Theta Burst Stimulation of the Human Cerebellum
. [Masters Thesis]. University of Otago; Available from: http://hdl.handle.net/10523/6009
Note: this citation may be lacking information needed for this citation format:
No year of publication.

University of Canterbury
28.
Doeltgen, Sebastian Heinrich.
The Effects of Neuromuscular Electrical Stimulation of the Submental Muscle Group on the Excitability of Corticobulbar Projections.
Degree: PhD, Speech and Language Therapy, 2009, University of Canterbury
URL: http://dx.doi.org/10.26021/8479
► Neuromuscular electrical stimulation (NMES) has become an increasingly popular rehabilitative treatment approach for swallowing disorders (dysphagia). However, its precise effects on swallowing biomechanics and measures…
(more)
▼ Neuromuscular electrical stimulation (NMES) has become an increasingly popular rehabilitative treatment approach for swallowing disorders (dysphagia). However, its precise effects on swallowing biomechanics and measures of swallowing neurophysiology are unclear. Clearly defined NMES treatment protocols that have been corroborated by thorough empirical research are lacking. The primary objective of this research programme was therefore to establish optimal NMES treatment parameters for the anterior hyo-mandibular (submental) musculature, a muscle group that is critically involved in the oral and pharyngeal phases of swallowing. Based on previous research, the primary hypothesis was that various NMES treatment protocols would have differential effects of either enhancing or inhibiting the excitability of corticobulbar projections to this muscle group. The research paradigm used to test this hypothesis was an evaluation of MEP amplitude and onset latency, recorded in the functional context of volitional contraction of the submental musculature (VC) and contraction of this muscle group during the pharyngeal phase of volitional swallowing (VPS, volitional pharyngeal swallow). Outcome measures were recorded before and at several time points after each NMES treatment trial. This methodology is similar to, but improved upon, research paradigms previously reported.
Changes in corticobulbar excitability in response to various NMES treatment protocols were recorded in a series of experiments. Ten healthy research participants were recruited into a study that evaluated the effects of event-related NMES, whereas 15 healthy research participants were enrolled in a study that investigated the effects of non-event-related NMES. In a third cohort of 35 healthy research participants, task-dependent differences in corticobulbar excitability were evaluated during three conditions of submental muscle contraction: VC, VPS and submental muscle contraction during the pharyngeal phase of reflexive swallowing (RPS, reflexive pharyngeal swallowing).
Event-related NMES induced frequency-depended changes in corticobulbar excitability. NMES administered at 80 Hz facilitated MEP amplitude, whereas NMES at 5 Hz and 20 Hz inhibited MEP amplitude. No changes were observed after NMES at 40 Hz. Maximal excitatory or inhibitory changes occurred 60 min post-treatment. Changes in MEP amplitude in response to event-related NMES were only observed when MEPs were recorded during the VC condition, whereas MEPs recorded during the VPS condition remained unaffected. Non-event-related NMES did not affect MEP amplitude in either of the muscle contraction conditions. Similarly, MEP onset latencies remained unchanged across all comparisons. MEPs were detected most consistently during the VC contraction condition. They were less frequently detected and were smaller in amplitude for the VPS condition and they were infrequently detected during pre-activation by RPS.
The documented results indicate that event-related NMES has a more substantial impact on…
Subjects/Keywords: Neuromuscular electrical stimulation (NMES); transcranial magnetic stimulation (TMS); motor evoked potential (MEP); deglutition; motor control
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Doeltgen, S. H. (2009). The Effects of Neuromuscular Electrical Stimulation of the Submental Muscle Group on the Excitability of Corticobulbar Projections. (Doctoral Dissertation). University of Canterbury. Retrieved from http://dx.doi.org/10.26021/8479
Chicago Manual of Style (16th Edition):
Doeltgen, Sebastian Heinrich. “The Effects of Neuromuscular Electrical Stimulation of the Submental Muscle Group on the Excitability of Corticobulbar Projections.” 2009. Doctoral Dissertation, University of Canterbury. Accessed March 05, 2021.
http://dx.doi.org/10.26021/8479.
MLA Handbook (7th Edition):
Doeltgen, Sebastian Heinrich. “The Effects of Neuromuscular Electrical Stimulation of the Submental Muscle Group on the Excitability of Corticobulbar Projections.” 2009. Web. 05 Mar 2021.
Vancouver:
Doeltgen SH. The Effects of Neuromuscular Electrical Stimulation of the Submental Muscle Group on the Excitability of Corticobulbar Projections. [Internet] [Doctoral dissertation]. University of Canterbury; 2009. [cited 2021 Mar 05].
Available from: http://dx.doi.org/10.26021/8479.
Council of Science Editors:
Doeltgen SH. The Effects of Neuromuscular Electrical Stimulation of the Submental Muscle Group on the Excitability of Corticobulbar Projections. [Doctoral Dissertation]. University of Canterbury; 2009. Available from: http://dx.doi.org/10.26021/8479
29.
Cross, Katy.
Neural systems for preparatory and reactive imitation control.
Degree: Neuroscience, 2013, UCLA
URL: http://www.escholarship.org/uc/item/4cj0x4pk
► Humans have an automatic tendency to imitate, as illustrated by unconscious mimicry during social interactions and behavioral interference effects in the laboratory. Automatic imitation is…
(more)
▼ Humans have an automatic tendency to imitate, as illustrated by unconscious mimicry during social interactions and behavioral interference effects in the laboratory. Automatic imitation is thought to arise from activation of the imitative motor representation during action observation, which is likely mediated by the overlapping representation of observed and executed actions in the mirror neuron system. In contrast to mechanisms of automatic imitation, models attempting to explain how automatic imitative tendencies are brought under intentional control are incomplete. In this dissertation, I use functional magnetic resonance imaging (fMRI) and transcranial magnetic stimulation (TMS) to measure and disrupt neural activity during imitation interference tasks to expand current models of imitation control. In particular, I focus on dissociating imitation control from control over a related prepotent response tendency – spatial compatibility – to determine (1) whether control mechanisms involved in overcoming automatic response tendencies evoked by action observation utilize a dedicated mechanism and (2) whether imitation control involves modulation of the mirror neuron system. In addition, I explore the hypothesis that imitative control mechanisms may differ depending on whether control is exerted in reaction to a stimulus (after the automatic response tendency has been evoked) or in advance of a stimulus (reducing the degree of automatic response activation in the first place).Results indicate that neural systems involved in reactive control of imitation are dissociable from those involved in controlling spatially compatible response tendencies. I propose a model of reactive imitation control involving interactions between prefrontal control regions and the mirror neuron system. In contrast to reactive control, I found no evidence of a dissociable preparatory imitation control mechanism in an fMRI study. However, TMS results suggest that preparatory control of imitation involves suppression of MNS activity, which can be reconciled with neuroimaging results through a general control that reduces the influence of visual input on the motor system. Thus, regardless of the timing, imitation control seems to involve modulation of MNS activity through interactions between general cognitive control systems and the more specific imitation circuits.
Subjects/Keywords: Neurosciences; Cognitive control; functional magnetic resonance imaging (fMRI); Imitation; Mirror neuron system; Transcranial magnetic stimulation (TMS)
…resonance imaging (fMRI) and
transcranial magnetic stimulation (TMS). Drawing… …the human mirror neuron system using single pulse transcranial
magnetic stimulation (… …73
Experiment 3.2. Theta-burst stimulation fails to modulate reactive
imitation control… …Figure 3.6: TMS targeting… …dissertation is to understand
neural mechanisms of imitation control using functional magnetic…
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APA (6th Edition):
Cross, K. (2013). Neural systems for preparatory and reactive imitation control. (Thesis). UCLA. Retrieved from http://www.escholarship.org/uc/item/4cj0x4pk
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Cross, Katy. “Neural systems for preparatory and reactive imitation control.” 2013. Thesis, UCLA. Accessed March 05, 2021.
http://www.escholarship.org/uc/item/4cj0x4pk.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Cross, Katy. “Neural systems for preparatory and reactive imitation control.” 2013. Web. 05 Mar 2021.
Vancouver:
Cross K. Neural systems for preparatory and reactive imitation control. [Internet] [Thesis]. UCLA; 2013. [cited 2021 Mar 05].
Available from: http://www.escholarship.org/uc/item/4cj0x4pk.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Cross K. Neural systems for preparatory and reactive imitation control. [Thesis]. UCLA; 2013. Available from: http://www.escholarship.org/uc/item/4cj0x4pk
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Alberta
30.
Mang, Cameron Scott.
Changes in corticospinal excitability induced by
neuromuscular electrical stimulation.
Degree: MS, Physical Education and Recreation, 2010, University of Alberta
URL: https://era.library.ualberta.ca/files/8910jt74h
► This thesis describes experiments designed to investigate the effects of neuromuscular electrical stimulation (NMES) on corticospinal (CS) excitability in humans. NMES delivered at 100 Hz…
(more)
▼ This thesis describes experiments designed to
investigate the effects of neuromuscular electrical stimulation
(NMES) on corticospinal (CS) excitability in humans. NMES delivered
at 100 Hz was more effective for increasing CS excitability than
10-, 50-, or 200-Hz NMES. CS excitability increases occurred after
24 min of 100-Hz NMES, were strongest in the stimulated muscle, and
were mediated primarily at a supraspinal level. NMES of the common
peroneal nerve of the leg increased CS excitability in multiple leg
muscles, whereas NMES of the median nerve of the hand increased CS
excitability in only the muscle innervated by that nerve.
Additionally, CS excitability for the hand increased after 40 min
of relatively high intensity and frequency NMES but not after 2 h
of lower intensity and frequency NMES. These results have
implications for identifying optimal NMES parameters to augment CS
excitability for rehabilitation after central nervous system
injury.
Subjects/Keywords: motor cortex; corticospinal excitability; neuromuscular electrical stimulation; stimulation frequency; transcranial magnetic stimulation
Record Details
Similar Records
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Share »
Record Details
Similar Records
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Mang, C. S. (2010). Changes in corticospinal excitability induced by
neuromuscular electrical stimulation. (Masters Thesis). University of Alberta. Retrieved from https://era.library.ualberta.ca/files/8910jt74h
Chicago Manual of Style (16th Edition):
Mang, Cameron Scott. “Changes in corticospinal excitability induced by
neuromuscular electrical stimulation.” 2010. Masters Thesis, University of Alberta. Accessed March 05, 2021.
https://era.library.ualberta.ca/files/8910jt74h.
MLA Handbook (7th Edition):
Mang, Cameron Scott. “Changes in corticospinal excitability induced by
neuromuscular electrical stimulation.” 2010. Web. 05 Mar 2021.
Vancouver:
Mang CS. Changes in corticospinal excitability induced by
neuromuscular electrical stimulation. [Internet] [Masters thesis]. University of Alberta; 2010. [cited 2021 Mar 05].
Available from: https://era.library.ualberta.ca/files/8910jt74h.
Council of Science Editors:
Mang CS. Changes in corticospinal excitability induced by
neuromuscular electrical stimulation. [Masters Thesis]. University of Alberta; 2010. Available from: https://era.library.ualberta.ca/files/8910jt74h
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