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1.
Silva, Emerson Rodrigo da.
Estudo das propriedades do biospeckle e suas aplicações.
Degree: Mestrado, Física, 2007, University of São Paulo
URL: http://www.teses.usp.br/teses/disponiveis/43/43134/tde-02102007-104941/ 
;
► Esta dissertação é dedicada ao estudo de algumas das propriedades e aplicações do speckle dinâmico no monitoramento de atividade em tecidos biológicos. As estatísticas espaço-temporais…
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▼ Esta dissertação é dedicada ao estudo de algumas das propriedades e aplicações do speckle dinâmico no monitoramento de atividade em tecidos biológicos. As estatísticas espaço-temporais de primeira e segunda ordem são discutidas em vias gerais. As principais técnicas para obtenção de dados a partir do granulado óptico são apresentadas, com especial destaque para a função de autocorrelação, as matrizes de co-ocorrência, o método de Fujii e a Análise de Contraste do Laser Speckle (LASCA). Uma nova metodologia de análise, baseada no estudo do contraste das correlações sucessivas, é proposta. Diversas simulações numéricas, utilizando diferentes funções densidade de probabilidade para as velocidades dos centros espalhadores, foram realizadas com intuito de testar os métodos de análise e fornecer subsídios para a interpretação de resultados in vivo. Tecidos vegetais e animais foram investigados, realizando-se o monitoramento do processo de senescência e mapas de vascularização em folhas, acompanhamento de frutos contaminados por fungos, mapeamento de atividade em flores e análise de cicatrização em ratos submetidos à cirurgia abdominal. Ensaios explorando o uso do biospeckle em microscopia são implementados. Por fim, é avaliado o potencial da técnica como ferramenta de diagnóstico em um caso de úlcera venosa crônica submetida a tratamento por meio de laserterapia de baixa intensidade. Os resultados encontrados revelaram o grande potencial em aplicações biológicas, através da construção de mapas que permitiram, por exemplo, a visualização detalhada da rede vascular de folhas vegetais. Também foi possível a identificação de áreas atacadas por micro organismos. Os estudos em tecidos animais e humanos apontaram perspectivas bastante promissoras do uso do biospeckle em ambiente clínico.
This master thesis is devoted to the study of some properties and applications of dynamic speckles on monitoring of activity in biological tissues. The first and second order space-time statistics are dicussed in an overview perspective. The main techniques used to obtain information from grainy pattern are presented, with special prominence to autocorrelation function, co-occurrence matrices, Fujii's method and the Laser Speckle Contrast Analisys (LASCA). A new methodology, based on the study of the contrast of sucessive correlations, is proposed. Several numerical simulations, using different probability density functions to velocities of scatterers, are done in order to test the analysis methods and supply subsidies for interpretation of in vivo results. Vegetable and animal tissues are investigated by monitoring of senescence process and construction of vascularization maps of leaves, accompanying of fungi contamined fruits, mapping of activity in flowers and analysis of healing in rats undergone to abdominal surgery. Experiments using the biospeckle phenomenon in microscopy are carried out. At last, it is evaluated the potentiality of the technique as diagnosis tool in a chronic vein ulcer undergone to treatment through low intensity…
Advisors/Committee Members: Muramatsu, Mikiya.
Subjects/Keywords: Atividade Biológica; Biological activity; Biospeckle; Biospeckle; Diagnóstico por Imagem; Imaging diagnostic; non-contact testing.; Teste não-destrutivo
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APA (6th Edition):
Silva, E. R. d. (2007). Estudo das propriedades do biospeckle e suas aplicações. (Masters Thesis). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/43/43134/tde-02102007-104941/ ;
Chicago Manual of Style (16th Edition):
Silva, Emerson Rodrigo da. “Estudo das propriedades do biospeckle e suas aplicações.” 2007. Masters Thesis, University of São Paulo. Accessed January 17, 2021.
http://www.teses.usp.br/teses/disponiveis/43/43134/tde-02102007-104941/ ;.
MLA Handbook (7th Edition):
Silva, Emerson Rodrigo da. “Estudo das propriedades do biospeckle e suas aplicações.” 2007. Web. 17 Jan 2021.
Vancouver:
Silva ERd. Estudo das propriedades do biospeckle e suas aplicações. [Internet] [Masters thesis]. University of São Paulo; 2007. [cited 2021 Jan 17].
Available from: http://www.teses.usp.br/teses/disponiveis/43/43134/tde-02102007-104941/ ;.
Council of Science Editors:
Silva ERd. Estudo das propriedades do biospeckle e suas aplicações. [Masters Thesis]. University of São Paulo; 2007. Available from: http://www.teses.usp.br/teses/disponiveis/43/43134/tde-02102007-104941/ ;
University of Debrecen
2.
Hohl, Enikő.
O,N heterociklusos vegyületek fragmentációjának tanulmányozása atmoszférikus nyomású kémiai ionizációs körülmények között
.
Degree: DE – TEK – Természettudományi és Technológiai Kar – Kémiai Intézet, 2011, University of Debrecen
URL: http://hdl.handle.net/2437/108514
► Diplomamunkám során O,N heterociklusok lágyionizációs módszerrel történő fragmentációját végeztem APCI körülmények között. A vizsgált anyag négy izomerjének fragmentációs útvonalait MS/MS és pszeudo MS3 mérésekkel térképeztem…
(more)
▼ Diplomamunkám sorá
n O,
N heterociklusok lágyionizációs módszerrel történő fragmentációját végeztem APCI körülmények között. A vizsgált anyag négy izomerjének fragmentációs útvonalait MS/MS és pszeudo MS3 mérésekkel térképeztem fel. Elkészítettem az egyik izomer részletes fragmentációs sémáját, és igazoltam a fragmensek szerkezetét. Kimutattam gyökionok képződését is az egyszeres töltésű protonált lezárt héjú kationok mellett. Vizsgáltam a különböző izomerek fragmentációjában való eltéréseket. Ehhez a másik három izomer spektrumait is felvettem. Az első két (1. és 2.) izomer eseté
n három fő fragmens képződik. NO2 vesztéssel keletkezik az A termékion, a 3, 4 és 6, 7 szénatomok közötti kötések hasadásával képződik a B, valamint az 5-ös nitrogé
n, 4-es szénatom és a 6, 7 szénatomok közötti kötések hasadásával alakul ki a C termékion. Az utóbbi két fragmens a krománt is tartalmazó molekularészek lehasadásával képződik. Ezeket pszeudo MS3 mérésben kiválasztottam és azonosítottam a spektrumokon megjelenő jelentősebb intenzitású csúcsokat.
Az MS/MS és MS3 tömegspektrumok tanulmányozásával megállapítottam, hogy az 1. és 2. izomer fragmentációs mechanizmusa megegyezik. Eltéréseket a 3. és 4. izomer eseté
n tapasztaltam. A 3. izomernél a 13-as C atom a 6-os C atom helyett a 4-eshez kötődik, a 4. izomernél pedig az 5-ös
N atom fel van cserélve 4-es C atommal. Igazoltam, hogy ezek a változások az izomereknél egymástól eltérő fragmentációt eredményeznek. Ennek eredményeként a 3. izomer eseté
n NO2 lehasadást nem tapasztaltam, csak nagy energiáknál. A 7-es és 8a valamint az 1-es
O és 2-es C atomok közötti kötések hasadása következményként kialakuló csúcs az első két izomer spektrumában gyakorlatilag meg sem jelenik. Hasonlóság a többi izomerrel, hogy az első jelentősebb intenzitású fragmens a 3. izomer eseté
n is .OH vesztéssel keletkezik. Megjelentek a többi izomerre jellemző fragmensek is, hasonló intenzitással.
A 4. izomer eseté
n ismét látható az NO2 vesztéssel képződő A fragmens. A 3. és 4. izomerekre egyaránt jellemző az m/z 215 csúcsot, valamint a 4. izomer eseté
n megjelenő m/z 355 csúcsot nem sikerült azonosítani. Ezek a szerkezetek valamilyen átrendeződés eredményeként jöhettek létre.
A négy izomer esetében az ütközési energia függvényében ábrázolva a disszociálatlan hányadot megállapítottam, hogy az izomerek fragmentációs stabilitása hasonló, az 1. és 2. izomer eseté
n pedig megegyező.
Ezen vegyületek származékai a jövőben esetleg orvosi szempontból is alkalmazhatóak lesznek különböző betegségek (például: Altzheimer-kór, Skizofrénia) kezelésére, így fontos, hogy ismerjük fragmentációs mechanizusukat.
Advisors/Committee Members: Nagy, Lajos (advisor).
Subjects/Keywords: fragmentáció;
O,N heterociklus
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APA ·
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Manager
APA (6th Edition):
Hohl, E. (2011). O,N heterociklusos vegyületek fragmentációjának tanulmányozása atmoszférikus nyomású kémiai ionizációs körülmények között
. (Thesis). University of Debrecen. Retrieved from http://hdl.handle.net/2437/108514
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Hohl, Enikő. “O,N heterociklusos vegyületek fragmentációjának tanulmányozása atmoszférikus nyomású kémiai ionizációs körülmények között
.” 2011. Thesis, University of Debrecen. Accessed January 17, 2021.
http://hdl.handle.net/2437/108514.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Hohl, Enikő. “O,N heterociklusos vegyületek fragmentációjának tanulmányozása atmoszférikus nyomású kémiai ionizációs körülmények között
.” 2011. Web. 17 Jan 2021.
Vancouver:
Hohl E. O,N heterociklusos vegyületek fragmentációjának tanulmányozása atmoszférikus nyomású kémiai ionizációs körülmények között
. [Internet] [Thesis]. University of Debrecen; 2011. [cited 2021 Jan 17].
Available from: http://hdl.handle.net/2437/108514.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Hohl E. O,N heterociklusos vegyületek fragmentációjának tanulmányozása atmoszférikus nyomású kémiai ionizációs körülmények között
. [Thesis]. University of Debrecen; 2011. Available from: http://hdl.handle.net/2437/108514
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
3.
Fiamingo, Anderson.
Membranas porosas de N,O-carboximetilquitosana/quitosana para aplicação na prevenção de adesões pericárdicas pós-cirúrgicas.
Degree: Mestrado, Físico-Química, 2012, University of São Paulo
URL: http://www.teses.usp.br/teses/disponiveis/75/75134/tde-17042012-171004/
;
► Este trabalho teve como objetivo produzir e caracterizar membranas de quitosana e de N,O-carboximetilquitosana reticuladas, que apresentassem propriedades físicas e químicas adequadas para desempenhar o…
(more)
▼ Este trabalho teve como objetivo produzir e caracterizar membranas de quitosana e de
N,
O-carboximetilquitosana reticuladas, que apresentassem propriedades físicas e químicas adequadas para desempenhar
o papel de matriz para proliferaçã
o das células mesoteliais. As características estruturais e morfológicas das amostras purificadas de quitosana (amostra Q, adquirida da Yue Planting, China) e carboximetilquitosana na forma sódica (amostra NaCMQH, adquirida da Heppe Medical, Alemanha, e amostra NaCMQD, adquirida da Dayang Chemicals, China) foram investigadas através da espectroscopias de ressonância magnética nuclear e no infravermelho, condutimetria, solubilidade em funçã
o do pH e viscosimetria. As membranas de carboximetilquitosanas (amostras M-CMQHs e M-CMQDs) foram confeccionadas via liofilizaçã
o, e glutaraldeído foi empregado como agente reticulante em diferentes concentrações para avaliar
o seu efeito sobre
o grau de reticulaçã
o e propriedades das membranas. As membranas foram caracterizadas quanto ao grau de reticulaçã
o, grau de hidrataçã
o, microscopia eletrônica de varredura (MEV), termogravimetria,
teste mecânico de traçã
o e quanto a susceptibilidade à degradaçã
o enzimática. A amostra Q apresentou grau médio de acetilaçã
o (<span style=\"text-decoration: overline\">GA) de 23,60%, sendo solúvel em pH ≤ 6,5. A amostra NaCMQH apresentou <span style=\"text-decoration: overline\">GA = 16,32% e grau médio de substituiçã
o (<span style=\"text-decoration: overline\">GS) de 1,68, sendo insolúvel no intervalo 2,5 ≤ pH ≤ 6,5, a amostra de NaCMQD apresentou <span style=\"text-decoration: overline\">GA = 3,31% e <span style=\"text-decoration: overline\">GS = 1,43, sendo insolúvel no intervalo 3,0 ≤ pH ≤ 7,0. A reticulaçã
o das membranas de carboximetilquitosana (amostras M-CMQHs e M-CMQDs) foi realizada com a finalidade de reduzir sua solubilidade e melhorar as propriedades mecânicas.
O grau médio de reticulaçã
o (<span style=\"text-decoration: overline\">GR) foi tanto maior quanto maior a concentraçã
o de glutaraldeído empregada na reaçã
o, variando de <span style=\"text-decoration: overline\">GR = 10,39 ± 0,37% ([glutaraldeído] = 2,5x10-3 mol L-1) a <span style=\"text-decoration: overline\">GR = 62,38 ± 1,71% ([glutaraldeído] = 5,0x10-3 mol L-1). As características morfológicas das amostras M-Q, M-CMQHs e M-CMQDs foram observadas pelo emprego de MEV, sendo observada a formaçã
o de estruturas porosas, com maior quantidade de poros aparentes quanto maior
o <span style=\"text-decoration: overline\">GM de 175 poros mm-2 a 291 poros mm-2 com
o aumento do grau de reticulaçã
o de 12,30% (amostra M-CMQH-2,5) para 35,82%, (amostra M-CMQH-50). A amostra M-Q apresentou baixa taxa de hidrataçã
o (321,16 ± 18,68%) e alto percentual de massa recuperada (90,62 ± 2,13%) após imersã
o por 24 horas em soluçã
o PBS, quando comparada às amostras M-CMQHs e M-CMQDs. As amostras M-CMQHs e M-CMQDs apresentaram aumento da resistência máxima à traçã
o com
o aumento de <span style=\"text-decoration: overline\"> <span…
Advisors/Committee Members: Campana Filho, Sergio Paulo.
Subjects/Keywords: chitosan; glutaraldehyde; glutaraldeído; N,O-carboximetilquitosana; N,O-carboxymethylchitosan; quitosana
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APA ·
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APA (6th Edition):
Fiamingo, A. (2012). Membranas porosas de N,O-carboximetilquitosana/quitosana para aplicação na prevenção de adesões pericárdicas pós-cirúrgicas. (Masters Thesis). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/75/75134/tde-17042012-171004/ ;
Chicago Manual of Style (16th Edition):
Fiamingo, Anderson. “Membranas porosas de N,O-carboximetilquitosana/quitosana para aplicação na prevenção de adesões pericárdicas pós-cirúrgicas.” 2012. Masters Thesis, University of São Paulo. Accessed January 17, 2021.
http://www.teses.usp.br/teses/disponiveis/75/75134/tde-17042012-171004/ ;.
MLA Handbook (7th Edition):
Fiamingo, Anderson. “Membranas porosas de N,O-carboximetilquitosana/quitosana para aplicação na prevenção de adesões pericárdicas pós-cirúrgicas.” 2012. Web. 17 Jan 2021.
Vancouver:
Fiamingo A. Membranas porosas de N,O-carboximetilquitosana/quitosana para aplicação na prevenção de adesões pericárdicas pós-cirúrgicas. [Internet] [Masters thesis]. University of São Paulo; 2012. [cited 2021 Jan 17].
Available from: http://www.teses.usp.br/teses/disponiveis/75/75134/tde-17042012-171004/ ;.
Council of Science Editors:
Fiamingo A. Membranas porosas de N,O-carboximetilquitosana/quitosana para aplicação na prevenção de adesões pericárdicas pós-cirúrgicas. [Masters Thesis]. University of São Paulo; 2012. Available from: http://www.teses.usp.br/teses/disponiveis/75/75134/tde-17042012-171004/ ;
University of Newcastle
4.
Khan, Naseer Ahmed.
Selective oxidation of methane with nitrous oxide over cobalt catalyst.
Degree: PhD, 2016, University of Newcastle
URL: http://hdl.handle.net/1959.13/1312052
► Research Doctorate - Doctor of Philosophy (PhD)
In spite of the highly fluctuating oil prices seen over the past number of years, the availability of…
(more)
▼ Research Doctorate - Doctor of Philosophy (PhD)
In spite of the highly fluctuating oil prices seen over the past number of years, the availability of relatively inexpensive sources of liquid hydrocarbons is diminishing, and the development of economically and environmentally viable alternative technologies to supply these hydrocarbons is vital. Projecting into the short and mid-term futures, the world economy is expected to continue to depend on hydrocarbon resources for stability, and thus technologies to produce these resources are important. Synthesis gas (CO and H₂), can be produced from a number of sources and feedstocks, such as biomass, waste and natural gas, and synthesis gas can be converted into liquid fuels such as hydrocarbons and alcohols, which are currently produced in large quantities in the conventional petrochemical industry. The selective oxidation of hydrocarbons, and in particular natural gas of which CH₄ the primary constituent, is notoriously difficult to control, mainly due to propensity of the reaction to generate to products of complete combustion. N₂O is a potent greenhouse gas (CO₂(e) = 300) and its concentration in the atmosphere is continuously increasing [Lee, Ryu et al, International Journal of Greenhouse Gas Control, January 2011, Pages 167–176]. Despite its greenhouse gas notoriety, N₂O is also recognised as a more selective oxidant than O₂ and has been used to selectively oxidise CH₄ to produce valuable products including synthesis gas. The production of synthesis gas, via its reaction with N₂O could be beneficial environmentally, as it could be used to provide valuable products when used to reaction with natural gas. The main aim of this research work is to investigate the scope of selective oxidation of natural gas (mainly CH₄) with N₂O over cobalt catalysts. The catalytic work was carried out in a continuous flow fixed bed micro reactor. Catalysts were prepared according to literature methods, as well as a new novel deposition method. The techniques used for catalyst characterization were powder X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), In situ Fourier transform infrared spectroscopy (FTIR), nitrogen adsorption/desorption isotherms, temperature program desorption (TPD), chemisorption, transmission electron microscopy (TEM). The elemental composition of catalyst samples was determined by using inductively coupled plasma optical emission spectrometer (ICP-OES). Based upon the experimental results obtained, the oxidation of CH₄ with N₂O over cobalt exchanged ZSM-5 (Co-ZSM-5) catalyst produced synthesis gas at a relatively high yield (19 %). When O₂ (instead of N₂O) was used as an oxidant over Co-ZSM-5 catalyst, synthesis gas was not formed. Similarly, when CH₄ and N₂O reacted over a cobalt on alumina catalyst, synthesis gas was not produced. Interestingly, H₂ was not detected as a reaction product when CH₄ with N₂O reacted over a Fe-ZSM-5 catalyst and only COx and H₂O were formed. The effect of the molar feed ratio (N₂O/CH₄ = 1, 3, and 5) was…
Advisors/Committee Members: University of Newcastle. Faculty of Engineering & Built Environment, School of Engineering.
Subjects/Keywords: CH₄; N₂O; Co-ZSM-5
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APA ·
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Manager
APA (6th Edition):
Khan, N. A. (2016). Selective oxidation of methane with nitrous oxide over cobalt catalyst. (Doctoral Dissertation). University of Newcastle. Retrieved from http://hdl.handle.net/1959.13/1312052
Chicago Manual of Style (16th Edition):
Khan, Naseer Ahmed. “Selective oxidation of methane with nitrous oxide over cobalt catalyst.” 2016. Doctoral Dissertation, University of Newcastle. Accessed January 17, 2021.
http://hdl.handle.net/1959.13/1312052.
MLA Handbook (7th Edition):
Khan, Naseer Ahmed. “Selective oxidation of methane with nitrous oxide over cobalt catalyst.” 2016. Web. 17 Jan 2021.
Vancouver:
Khan NA. Selective oxidation of methane with nitrous oxide over cobalt catalyst. [Internet] [Doctoral dissertation]. University of Newcastle; 2016. [cited 2021 Jan 17].
Available from: http://hdl.handle.net/1959.13/1312052.
Council of Science Editors:
Khan NA. Selective oxidation of methane with nitrous oxide over cobalt catalyst. [Doctoral Dissertation]. University of Newcastle; 2016. Available from: http://hdl.handle.net/1959.13/1312052
5.
Maria Claudia Tonelli Largura.
Síntese e caracterização da o-carboximetilquitosana-n-lauril e utilização como polímero anfifílica em comprimidos de triancinolona.
Degree: 2009, Universidade do Vale do Itajaí
URL: http://www6.univali.br/tede/tde_busca/arquivo.php?codArquivo=713
► A tecnologia associada à modificação da liberação de fármacos sofreu um incremento notório nas últimas décadas na tentativa de maximizar as vantagens inerentes às formas…
(more)
▼ A tecnologia associada à modificaçã
o da liberaçã
o de fármacos sofreu um incremento notório nas últimas décadas na tentativa de maximizar as vantagens inerentes às formas farmacêuticas de liberaçã
o controlada. A utilizaçã
o de sistemas matriciais constituídos por diversos tipos de polímeros é considerada uma opçã
o interessante, devido às vantagens desses sistemas. A quitosana (Qts) (poli – (1-4)Dglucosamina) é um polissacarídeo catiônico derivado da quitina, de fácil obtençã
o e com muitas aplicações industriais. Neste trabalho,
o derivado OCarboximetilquitosana (
O-CMQts) foi hidrofobicamente modificado com cloreto de lauroíla em diferentes concentrações, para obter um derivado da Qts com caráter anfifílico,
o O-Carboximetilquitosana-
N-Lauril (
O-CMQts-
N-Lauril), com diferentes graus de substituiçã
o (GS) e utilizá-lo como matriz na preparaçã
o de comprimidos de triancinolana (TC). A estrutura química dos derivados foi confirmada através das técnicas de espectroscopia no infravermelho (IV).
O grau de carboximetilaçã
o (GC) da
O-CMQts foi determinado através da titulaçã
o condutimétrica. Para determinar
o GS foi desenvolvido um método utilizando a espectroscopia no IV. A interaçã
o entre
o fármaco e
o polímero foi verificada de forma indireta através da quantificaçã
o do fármaco livre na dispersã
o polimérica. As propriedades tecnológicas dos derivados foram determinadas com
o objetivo de preparar comprimidos contendo
o fármaco através da compressã
o direta. Na preparaçã
o dos comprimidos, a TC foi incorporada à matriz dos derivados através da mistura física (MFT) e co-secagem fármaco: polímero por nebulizaçã
o (SDT). Os comprimidos foram caracterizados em relaçã
o a morfologia, absorçã
o de água e perfil de liberaçã
o do fármaco em meio gástrico simulado. Os derivados AC1 e AC2 apresentaram GS com valores entre 43,5 e 8,56 %. A quantidade de TC complexada aos derivados
N-acilados foi proporcional ao GS destes derivados.
O tamanho e a morfologia das partículas dos derivados
N-acilados foram influênciados pelo processo de obtençã
o e GS dos derivados. Os comprimidos SDT apresentaram resistência física maior quando comparado com os MFT, sendo que em ambos a resistência aumentou com
o GS do derivado. Os comprimidos apresentaram tempo de desintegraçã
o menor do que 15 min, exceto os comprimidos AC3T contendo 4 mg, que nã
o desintegraram em 300 min de análise. Nos comprimidos MFT (20 mg) a liberaçã
o máxima ocorreu em torno de 60 min, entretanto, a solubilidade do TC aumentou significativamente nos comprimidos preparados com derivados contendo GS elevado. Nos comprimidos SDT (20 mg) a proporçã
o de fármaco liberada por tempo foi dependente do derivado. Os comprimidos SDAC3T liberaram praticamente todo fármaco em 30 min, enquanto que os comprimidos SDAC1T liberaram cerca 16 % do fármaco no mesmo período de tempo. Os comprimidos contendo 4 mg de fármaco apresentaram liberaçã
o máxima em torno de 60 min, com exceçã
o dos comprimidos AC3T que liberaram cerca de 20 % de fármaco no mesmo intervalo de tempo. A partir dos resultados mostrados neste…
Advisors/Committee Members: Tania Mari Bellé Bresolin, Clovis Antonio Rodrigues, Ruth Meri Lucinda da Silva, Leticia Norma Carpentieri Rodrigues.
Subjects/Keywords: o-carboximetilquitosana- N-lauril; comprimidos; spray-drying liberação modificada; triancinolona; FARMACIA; o-carboxymethylchitosan-N-lauryl; tablets; spray-drying; modified release; triamcinolone
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APA (6th Edition):
Largura, M. C. T. (2009). Síntese e caracterização da o-carboximetilquitosana-n-lauril e utilização como polímero anfifílica em comprimidos de triancinolona. (Thesis). Universidade do Vale do Itajaí. Retrieved from http://www6.univali.br/tede/tde_busca/arquivo.php?codArquivo=713
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Largura, Maria Claudia Tonelli. “Síntese e caracterização da o-carboximetilquitosana-n-lauril e utilização como polímero anfifílica em comprimidos de triancinolona.” 2009. Thesis, Universidade do Vale do Itajaí. Accessed January 17, 2021.
http://www6.univali.br/tede/tde_busca/arquivo.php?codArquivo=713.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Largura, Maria Claudia Tonelli. “Síntese e caracterização da o-carboximetilquitosana-n-lauril e utilização como polímero anfifílica em comprimidos de triancinolona.” 2009. Web. 17 Jan 2021.
Vancouver:
Largura MCT. Síntese e caracterização da o-carboximetilquitosana-n-lauril e utilização como polímero anfifílica em comprimidos de triancinolona. [Internet] [Thesis]. Universidade do Vale do Itajaí; 2009. [cited 2021 Jan 17].
Available from: http://www6.univali.br/tede/tde_busca/arquivo.php?codArquivo=713.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Largura MCT. Síntese e caracterização da o-carboximetilquitosana-n-lauril e utilização como polímero anfifílica em comprimidos de triancinolona. [Thesis]. Universidade do Vale do Itajaí; 2009. Available from: http://www6.univali.br/tede/tde_busca/arquivo.php?codArquivo=713
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Kaunas University of Medicine
6.
Alenskas,
Tomas.
Chitosan utilization in antitubercular prodrugs
development.
Degree: Master, Pharmacy, 2010, Kaunas University of Medicine
URL: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2010~D_20100621_094749-03893
;
► The goal of the work was to evaluate conjugation of chitosan and its N-succinyl and O-carboxymethyl derivatives with particular first and second line antitubercular drugs…
(more)
▼ The goal of the work was to evaluate
conjugation of chitosan and its N-succinyl and O-carboxymethyl
derivatives with particular first and second line antitubercular
drugs and effect of phosphorylation for final products solubility.
Carbodiimide (EDC) was chosen to catalyze amide bond formation
between reactive materials. Firstly, water soluble N-succinyl and
O-carboxymethyl chitosan derivatives were prepared using low
molecular weight chitosan (Sigma-Aldrich). After that, these
derivatives were conjugated with low molecular weight
antitubercular drugs: isoniazid, para-amino-salicylic acid,
pyrazinecarboxamide, ethionamide and cycloserine. Acetylation of
quinolones was prepared in order to protect active amino group of
piperazine to act in conjugation. Non-modificated chitosan was
conjugated with acetylated quinolones- ciprofloxacin, enoxacin,
norfloxacin, lomefloxacin, sparfloxacin and non-acetylated
quinolones- ofloxacin and levofloxacin. Solubility in water of
final products was increased by phoshorylation. Phosphorylated
O-carboxymethyl chitosan derivatives with para-amino-salicylic
acid, pyrazinecarboxamide and ethionamide were completely soluble.
Analysis of infrared spectroscopy and melting point (for acetylated
quinolones) confirmed that reactions of acetylation and conjugation
were performed successfully.
Darbo tikslas buvo įvertinti chitosano ir jo
N-sukcinil bei O-karboksimetil darinių konjugaciją su tam tikrais
pirmos ir antros eilės antituberkulioziniais vaistais bei
fosforilinimo įtaką galutinių produktų tirpumui. Karbodiimidas
(EDC) buvo panaudotas katalizuoti amidinės jungties susidarymą tarp
reaguojančių medžiagų. Pirmiausiai, iš mažos molekulinės masės
chitosano (Sigma-Aldrich) buvo susintetinti vandenyje tirpesni jo
dariniai: N-sukcinil chitosanas ir O-karboksimetil chitosanas. Šie
dariniai buvo sujungti su mažos molekulinės masės
antituberkulioziniais vaistais: izoniazidu, para-amino-saliciline
rūgštimi, pirazinkarboksamidu, etionamidu ir cikloserinu. Chinolonų
piperazino žiedo amino grupė buvo acetilinta tam, kad apsaugoti ją
nuo dalyvavimo konjugacijos procese. Nemodifikuotas chitosanas buvo
sujungtas su acetilintais chinolonais- ciprofloksacinu, enoksacinu,
norfloksacinu, lomefloksacinu, sparfloksacinu ir neacetilintais
chinolonais- ofloksacinu, levofloksacinu. Fosforilinimas buvo
atliktas tam, kad padidinti konjugacijos produktų tirpumą
vandenyje. Fosforilinti O-karboksimetil chitosano dariniai su
para-amino-saliciline rūgštimi, pirazinkarboksamidu ir etionamidu
buvo visiškai tirpūs vandenyje. Infraraudonosios spektroskopijos ir
lydymosi temperatūros (acetilintiems kvinolonams) analizės
patvirtino, kad acetilinimo ir konjugacijos reakcijos buvo atliktos
sėkmingai.
Advisors/Committee Members: Vinšova, Jarmila (Master’s thesis supervisor), Briedis, Vitalis (Master’s thesis supervisor), Vavrikova, Eva (Master’s thesis advisor), Tarasevičius, Eduardas (Master’s thesis reviewer), Ivanauskas , Liudas (Master’s degree committee chair), Savickas , Arūnas (Master’s degree committee member), Radžiūnas , Raimondas (Master’s degree committee member), Briedis , Vitalis (Master’s degree committee member), Pečiūra , Rimantas (Master’s degree committee member), Ramanauskienė , Kristina (Master’s degree committee member), Janulis , Valdimaras (Master’s degree committee member).
Subjects/Keywords: Chitosan; O-carboxymethyl
chitosan; N-succinyl
chitosan; Prodrug; Tuberculosis; Chitosanas; O-karboksimetil
chitosanas; N-sukcinil
chitosanas; Provaistas; Tuberkuliozė
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APA ·
Chicago ·
MLA ·
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CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Alenskas,
Tomas. (2010). Chitosan utilization in antitubercular prodrugs
development. (Masters Thesis). Kaunas University of Medicine. Retrieved from http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2010~D_20100621_094749-03893 ;
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
Chicago Manual of Style (16th Edition):
Alenskas,
Tomas. “Chitosan utilization in antitubercular prodrugs
development.” 2010. Masters Thesis, Kaunas University of Medicine. Accessed January 17, 2021.
http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2010~D_20100621_094749-03893 ;.
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
MLA Handbook (7th Edition):
Alenskas,
Tomas. “Chitosan utilization in antitubercular prodrugs
development.” 2010. Web. 17 Jan 2021.
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
Vancouver:
Alenskas,
Tomas. Chitosan utilization in antitubercular prodrugs
development. [Internet] [Masters thesis]. Kaunas University of Medicine; 2010. [cited 2021 Jan 17].
Available from: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2010~D_20100621_094749-03893 ;.
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
Council of Science Editors:
Alenskas,
Tomas. Chitosan utilization in antitubercular prodrugs
development. [Masters Thesis]. Kaunas University of Medicine; 2010. Available from: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2010~D_20100621_094749-03893 ;
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
7.
Richier, Loïc.
Géométrie et percolation sur des cartes à bord aléatoires : Geometry and percolation on random maps with a boundary.
Degree: Docteur es, Mathématiques, 2017, Lyon
URL: http://www.theses.fr/2017LYSEN020
► Cette thèse porte sur des limites de grandes cartes à bord aléatoires. Dans un premier temps, nous nous intéressons aux propriétés géométriques de telles cartes.…
(more)
▼ Cette thèse porte sur des limites de grandes cartes à bord aléatoires. Dans un premier temps, nous nous intéressons aux propriétés géométriques de telles cartes. Nous montrons d'abord des résultats concernant les limites d'échelle et les limites locales du bord de cartes de Boltzmann dont le périmètre tend vers l'infini, que nous appliquons à l'étude du modèle O(n) rigide sur les quadrangulations. Ensuite, nous introduisons une famille de quadrangulations du demi-plan aléatoires avec un paramètre de torsion, dont on étudie les limites d'échelle et la structure de branchement. Enfin, nous établissons une propriété de confluence des géodésiques dans les cartes uniformes infinies du demi-plan, qui sont des limites locales de triangulations et quadrangulations à bord uniformes.Dans un second temps, nous considérons des modèles de percolation de Bernoulli sur les cartes uniformes infinies du demi-plan. Nous calculons le seuil de percolation par site critique pour les quadrangulations, et établissons une propriété d'universalité de ces modèles de percolation au point critique à partir des probabilités de croisement. Pour finir, nous étudions la limite locale de grands amas de percolation critiques en construisant l'amas critique émergent, une triangulation uniforme infinie du demi-plan munie d'un amas de percolation critique infini.
This thesis deals with limits of large random planar maps with a boundary. First, we are interested in geometric properties of such maps. We prove scaling and local limit results for the boundary of Boltzmann maps whose perimeter goes to infinity, which we apply to the study of the rigid O(n) loop model on quadrangulations. Next, we introduce a family of random half-planar quadrangulations with a skewness parameter, and study their scaling limits and branching structure. Finally, we establish a confluence property of geodesics in uniform infinite half-planar maps, which are local limits of uniform triangulations and quadrangulations with a boundary.Second, we consider Bernoulli percolation models on uniform infinite half-planar maps. We compute the critical site percolation threshold for quadrangulations, and prove a universality property of these percolation models at criticality involving crossing probabilities. To conclude, we study the local limit of large critical percolation clusters by defining the incipient infinite cluster, a uniform infinite half-planar triangulation equipped with an infinite critical percolation cluster.
Advisors/Committee Members: Miermont, Grégory (thesis director).
Subjects/Keywords: Cartes aléatoires; Percolation; Modèle O(n); Limites locales; Limites d'échelle; Random maps; Percolation; O(n) model; Local limits; Scaling limits
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Richier, L. (2017). Géométrie et percolation sur des cartes à bord aléatoires : Geometry and percolation on random maps with a boundary. (Doctoral Dissertation). Lyon. Retrieved from http://www.theses.fr/2017LYSEN020
Chicago Manual of Style (16th Edition):
Richier, Loïc. “Géométrie et percolation sur des cartes à bord aléatoires : Geometry and percolation on random maps with a boundary.” 2017. Doctoral Dissertation, Lyon. Accessed January 17, 2021.
http://www.theses.fr/2017LYSEN020.
MLA Handbook (7th Edition):
Richier, Loïc. “Géométrie et percolation sur des cartes à bord aléatoires : Geometry and percolation on random maps with a boundary.” 2017. Web. 17 Jan 2021.
Vancouver:
Richier L. Géométrie et percolation sur des cartes à bord aléatoires : Geometry and percolation on random maps with a boundary. [Internet] [Doctoral dissertation]. Lyon; 2017. [cited 2021 Jan 17].
Available from: http://www.theses.fr/2017LYSEN020.
Council of Science Editors:
Richier L. Géométrie et percolation sur des cartes à bord aléatoires : Geometry and percolation on random maps with a boundary. [Doctoral Dissertation]. Lyon; 2017. Available from: http://www.theses.fr/2017LYSEN020
Univerzitet u Beogradu
8.
Radovanović, Lidija D., 1980-.
Kompleksi elemenata d-bloka sa aromatičnim O,O- I N,
N-donorskim ligandima: sinteza, struktura, svojstva i
primena.
Degree: Tehnološko-metalurški fakultet, 2018, Univerzitet u Beogradu
URL: https://fedorabg.bg.ac.rs/fedora/get/o:18860/bdef:Content/get
► Tehnološko inženjerstvo - Inženjerstvo materijala / Technological Engineering - Materials Engineering
Reakcijom izmene liganada različitim metodama sinteze dobijeno je 22 ternarna kompleksa elemenata d-bloka [Mn(II),…
(more)
▼ Tehnološko inženjerstvo - Inženjerstvo materijala /
Technological Engineering - Materials Engineering
Reakcijom izmene liganada različitim metodama
sinteze dobijeno je 22 ternarna kompleksa elemenata d-bloka
[Mn(II), Co(II), Ni(II), Cu(II) i Zn(II)] sa anjonima aromatičnih
polikarboksilnih kiselina (ftalne, izoftalne, tereftalne i
piromelitne) kao O,O-donorskim ligandima i aromatičnim
N,N-donorskim ligandima kao što su 2,2'-dipiridilamin i
2,2'-bipirimidin. Trinaest kompleksa sintetisano je u
monokristalnom obliku, dok su ostala jedinjenja mikrokristalna.
Prema vrsti centralnog atoma, u obliku monokristala dobijeno je pet
Mn(II)-, dva Co(II)-, jedan Ni(II)-, dva Cu(II)-, dva
Zn(II)-kompleksa, kao i bimetalni
Mn(II)–Cu(II)-kompleks...
Advisors/Committee Members: Rogan, Jelena, 1971-.
Subjects/Keywords: complexes of d-block elements; crystal structures;
O; O-donor ligands; N; N-donor ligands; magnetism; photoluminescence;
antimicrobial activity; nanomaterials
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APA (6th Edition):
Radovanović, Lidija D., 1. (2018). Kompleksi elemenata d-bloka sa aromatičnim O,O- I N,
N-donorskim ligandima: sinteza, struktura, svojstva i
primena. (Thesis). Univerzitet u Beogradu. Retrieved from https://fedorabg.bg.ac.rs/fedora/get/o:18860/bdef:Content/get
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Radovanović, Lidija D., 1980-. “Kompleksi elemenata d-bloka sa aromatičnim O,O- I N,
N-donorskim ligandima: sinteza, struktura, svojstva i
primena.” 2018. Thesis, Univerzitet u Beogradu. Accessed January 17, 2021.
https://fedorabg.bg.ac.rs/fedora/get/o:18860/bdef:Content/get.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Radovanović, Lidija D., 1980-. “Kompleksi elemenata d-bloka sa aromatičnim O,O- I N,
N-donorskim ligandima: sinteza, struktura, svojstva i
primena.” 2018. Web. 17 Jan 2021.
Vancouver:
Radovanović, Lidija D. 1. Kompleksi elemenata d-bloka sa aromatičnim O,O- I N,
N-donorskim ligandima: sinteza, struktura, svojstva i
primena. [Internet] [Thesis]. Univerzitet u Beogradu; 2018. [cited 2021 Jan 17].
Available from: https://fedorabg.bg.ac.rs/fedora/get/o:18860/bdef:Content/get.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Radovanović, Lidija D. 1. Kompleksi elemenata d-bloka sa aromatičnim O,O- I N,
N-donorskim ligandima: sinteza, struktura, svojstva i
primena. [Thesis]. Univerzitet u Beogradu; 2018. Available from: https://fedorabg.bg.ac.rs/fedora/get/o:18860/bdef:Content/get
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
9.
Kalistratova, Aleksandra.
Tuning bioactive peptides properties : new developments in the O-N acyl transfer reaction and dimerization of unprotected peptides : Modulation des propriétés des peptides bioactifs : nouveaux développements de la réaction de transfert O-N acylique et dimérisation de peptides non protégés.
Degree: Docteur es, Ingénierie Biomoléculaire, 2016, Montpellier; Université de technologie chimique et de métallurgie de Sofia (UTCM)
URL: http://www.theses.fr/2016MONTT229
► L’intérêt des peptides comme des médicaments potentiels est en constante augmentation. Des stratégies ont été développées pour améliorer la sélectivité, l’activité, et la stabilité des…
(more)
▼ L’intérêt des peptides comme des médicaments potentiels est en constante augmentation. Des stratégies ont été développées pour améliorer la sélectivité, l’activité, et la stabilité des peptides vis-à-vis de la protéolyse. Dans ce mémoire de thèse, deux nouvelles modifications de peptides sont proposées.Dans le premier chapitre, nous présentons une nouvelle application de la réaction de transfert O-N acylique pour la synthèse de peptides agrafés (ou ‘stapled peptides’). L’introduction d’une ‘agrafe’ dans un peptide est un moyen de stabiliser une structure secondaire hélicoïdale en établissant un pont entre les résidus appropriés des chaînes latérales. Dans notre cas, l'agrafe est formée par un O-acyl isodipeptide. La liaison ester peut être convertie en liaison amide par un transfert O-N acylique. Cette stratégie permet une amélioration de la solubilité d’un peptide hydrophobe agrafé, avant son réarrangement à pH neutre.Dans le dernier chapitre, nous avons développé une méthodologie nouvelle pour la dimérisation de peptides non protégés. Cette méthode repose sur la formation de liaisons siloxane entre des peptides hybrides portant chacun un groupement dimethylchlorosilane. Nous avons ainsi dimérisé une séquence dérivée de la protéine p53, impliquée dans l’apoptose. A titre de comparaison, cette même séquence a été dimérisée en utilisant la cycloaddition d’Huisgen entre deux peptides modifiés possédant un azoture ou un alcyne en position N-terminale. Enfin, plusieurs dimères de la séquence du GHRP-6 (growth hormone releasing peptide) ont été synthétisés, avec des bras dimethylhydroxysilane placés à différentes positions. L’homodimérisation a été effectuée dans l'eau à pH neutre.
The interest in peptides as potential drug candidates was revived and is increasing constantly. Strategies have been developed to improve their selectivity and activity, and their stability toward proteolysis. In this thesis, two new peptide modifications are proposed.In the first chapter, we present a new application of the O-N acyl transfer reaction for the synthesis of stapled peptides. Peptide ‘stapling’ is a way of stabilizing secondary helical structure by establishment of a bridge between the side chains of suitable residues. In our case, the staple is formed by an O-acyl isopeptide which can be converted into amide bond by acyl migration. This strategy allows an improved solubility of the stapled hydrophobic peptide prior to rearrangement at neutral pH.In the last chapter, we developed also a new methodology for the dimerization of unprotected peptides. This method is based on siloxane bond formation between hybrid dimethylhydroxysilane peptides. A peptide derived from the tumor suppressor protein p53 was dimerized in water, at neutral pH using this methodology. The method was compared with the homodimerization carried out by Cu(I) azide-alkyne cycloaddition (CuAAC). For that purpose, p53 peptide derivative was synthesized with azide and alkyne linkers at the N-terminus. At last, several homodimers of growth hormone releasing…
Advisors/Committee Members: Subra, Gilles (thesis director), Naydenova, Emilia (thesis director).
Subjects/Keywords: Transfert O-N acylique; Peptides ‘agrafés’; Dimérisation; Homodimérisation; Peptides non protégés; O-N acyl transfer reaction; Stapled peptides; Dimerization; Homodimerization
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Kalistratova, A. (2016). Tuning bioactive peptides properties : new developments in the O-N acyl transfer reaction and dimerization of unprotected peptides : Modulation des propriétés des peptides bioactifs : nouveaux développements de la réaction de transfert O-N acylique et dimérisation de peptides non protégés. (Doctoral Dissertation). Montpellier; Université de technologie chimique et de métallurgie de Sofia (UTCM). Retrieved from http://www.theses.fr/2016MONTT229
Chicago Manual of Style (16th Edition):
Kalistratova, Aleksandra. “Tuning bioactive peptides properties : new developments in the O-N acyl transfer reaction and dimerization of unprotected peptides : Modulation des propriétés des peptides bioactifs : nouveaux développements de la réaction de transfert O-N acylique et dimérisation de peptides non protégés.” 2016. Doctoral Dissertation, Montpellier; Université de technologie chimique et de métallurgie de Sofia (UTCM). Accessed January 17, 2021.
http://www.theses.fr/2016MONTT229.
MLA Handbook (7th Edition):
Kalistratova, Aleksandra. “Tuning bioactive peptides properties : new developments in the O-N acyl transfer reaction and dimerization of unprotected peptides : Modulation des propriétés des peptides bioactifs : nouveaux développements de la réaction de transfert O-N acylique et dimérisation de peptides non protégés.” 2016. Web. 17 Jan 2021.
Vancouver:
Kalistratova A. Tuning bioactive peptides properties : new developments in the O-N acyl transfer reaction and dimerization of unprotected peptides : Modulation des propriétés des peptides bioactifs : nouveaux développements de la réaction de transfert O-N acylique et dimérisation de peptides non protégés. [Internet] [Doctoral dissertation]. Montpellier; Université de technologie chimique et de métallurgie de Sofia (UTCM); 2016. [cited 2021 Jan 17].
Available from: http://www.theses.fr/2016MONTT229.
Council of Science Editors:
Kalistratova A. Tuning bioactive peptides properties : new developments in the O-N acyl transfer reaction and dimerization of unprotected peptides : Modulation des propriétés des peptides bioactifs : nouveaux développements de la réaction de transfert O-N acylique et dimérisation de peptides non protégés. [Doctoral Dissertation]. Montpellier; Université de technologie chimique et de métallurgie de Sofia (UTCM); 2016. Available from: http://www.theses.fr/2016MONTT229
Princeton University
10.
Fei, Lin.
Conformal Field Theories in the Epsilon and 1/N Expansions
.
Degree: PhD, 2017, Princeton University
URL: http://arks.princeton.edu/ark:/88435/dsp0144558g94m
► In this thesis, we study various conformal field theories in two different approximation schemes - the epsilon-expansion in dimensional continuation, and the large N expansion.…
(more)
▼ In this thesis, we study various conformal field theories in two different approximation schemes - the epsilon-expansion in dimensional continuation, and the large
N expansion. We first propose a cubic theory in d=6-epsilon as the UV completion of the quartic scalar
O(
N) theory in d>4. We study this theory to three-loop order and show that various operator dimensions are consistent with large-
N results. This theory possesses an IR stable fixed point at real couplings for
N>1038, suggesting the existence of a perturbatively unitary interacting
O(
N) symmetric CFT in d=5. Extending this model to Sp(
N) symmetric theories, we find an interacting non-unitary CFT in d=5. For the special case of Sp(2), the IR fixed point possesses an enhanced symmetry given by the supergroup OSp(1|2). We also observe that various operator dimensions of the Sp(2) theory match those from the 0-state Potts model. We provide a graph theoretic proof showing that the zero, two, and three-point functions in the Sp(2) model and the 0-state Potts model indeed match to all orders in perturbation theory, strongly suggesting their equivalence. We then study two fermionic theories in d=2+epsilon - the Gross-Neveu model and the Nambu-Jona-Lasinio model, together with their UV completions in d=4-epsilon given by the Gross-Neveu-Yukawa and the Nambu-Jona-Lasinio-Yukawa theories. We compute their sphere free energy and certain operator dimensions, passing all checks against large-
N results. We use two sided Pad\'e approximations with our epsilon expansion results to obtain estimates of various quantities in the physical dimension d=3. Finally, we provide evidence that the
N=1 Gross-Neveu-Yukawa model which contains a 2-component Majorana fermion, and the
N=2 Nambu-Jona-Lasinion-Yukawa model which contains a 2-component Dirac fermion, both have emergent supersymmetry.
Advisors/Committee Members: Giombi, Simone (advisor).
Subjects/Keywords: conformal field theory;
epsilon expansion;
large N expansion;
O(N);
Potts;
supersymmetry
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APA (6th Edition):
Fei, L. (2017). Conformal Field Theories in the Epsilon and 1/N Expansions
. (Doctoral Dissertation). Princeton University. Retrieved from http://arks.princeton.edu/ark:/88435/dsp0144558g94m
Chicago Manual of Style (16th Edition):
Fei, Lin. “Conformal Field Theories in the Epsilon and 1/N Expansions
.” 2017. Doctoral Dissertation, Princeton University. Accessed January 17, 2021.
http://arks.princeton.edu/ark:/88435/dsp0144558g94m.
MLA Handbook (7th Edition):
Fei, Lin. “Conformal Field Theories in the Epsilon and 1/N Expansions
.” 2017. Web. 17 Jan 2021.
Vancouver:
Fei L. Conformal Field Theories in the Epsilon and 1/N Expansions
. [Internet] [Doctoral dissertation]. Princeton University; 2017. [cited 2021 Jan 17].
Available from: http://arks.princeton.edu/ark:/88435/dsp0144558g94m.
Council of Science Editors:
Fei L. Conformal Field Theories in the Epsilon and 1/N Expansions
. [Doctoral Dissertation]. Princeton University; 2017. Available from: http://arks.princeton.edu/ark:/88435/dsp0144558g94m
Universidade de Brasília
11.
André Gustavo de Araujo Fernandes.
Síntese e caracterização estrutural de complexos de oxorrênio (V) com ligantes O, O- e N, O- doadores.
Degree: 2007, Universidade de Brasília
URL: http://bdtd.bce.unb.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=1699
► In this work the coordination modes of O,O- and N,O-donor complexing agents have been studied. Trichlorobis(triphenylphosphine)oxorhenium(V), [ReOCl3(PPh3)2], and tribromobis(triphenylphosphine)oxorhenium(V), [ReOBr3(PPh3)2], were used as starting materials…
(more)
▼ In this work the coordination modes of O,O- and N,O-donor complexing agents have been studied. Trichlorobis(triphenylphosphine)oxorhenium(V), [ReOCl3(PPh3)2], and tribromobis(triphenylphosphine)oxorhenium(V), [ReOBr3(PPh3)2], were used as starting materials to obtain eight rhenium(V) complexes. The precursor tetrabutylammonium tetrachlorooxorhenate(V), [NBu4][ReOCl4], was used to prepare an additional rhenium(V) complex. All the rhenium complexes presented here were obtained in good yield, being all of the hexacoordenated type [ReOX2L(PPh3)] (X = Cl or Br and L- = monocharged bidentated ligand). The complexes were characterized by infrared absorption spectroscopy, melting point, elemental analyses (CHN), nuclear magnetic resonance spectroscopy (31P{1H}, 1H and, in some cases, also 13C) and had their crystalline and molecular structures determined by X-ray diffraction on single crystals.
Neste trabalho foram estudadas as formas de coordenação de agentes complexantes O,O- e N,O-doadores, ao centro metálico de Re(V). Os complexos triclorobis(trifenilfosfina)oxorrênio(V), [ReOCl3(PPh3)2], e tribromobis(trifenilfosfina)oxorrênio(V), [ReOBr3(PPh3)2], foram utilizados como materiais de partida para a obtenção de oito complexos de rênio. O precursor tetraclorooxorenato(V) de tetrabutilamônio, [NBu4][ReOCl4], foi utilizado na síntese de um complexo de rênio adicional. Todos os complexos de rênio(V) aqui apresentados foram obtidos com elevado rendimento, hexacoordenados do tipo [ReOX2L(PPh3)] (X = Cl ou Br e L- = ligante bidentado monoaniônico). Os complexos com kojato e picolinato apresentam ligações de hidrogênio intermoleculares. Todos os complexos descritos neste trabalho foram caracterizados por espectroscopia de absorção na região do infravermelho, ponto de fusão, análise elementar (CHN), espectroscopia de ressonância magnética nuclear (31P{1H}, 1H e, em alguns casos, também de 13C) e tiveram suas estruturas cristalinas e moleculares determinadas por difração de raios X em monocristal.
Advisors/Committee Members: Sebastião de Souza Lemos, Stela Maris de Moraes Romanowski, Vitor Marcelo Deflon.
Subjects/Keywords: difração de raixos X em monocristal; oxorrênio (V); medicina nuclear; ligantes O,O-; N, O- doadores; QUIMICA; quelato complexos
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APA (6th Edition):
Fernandes, A. G. d. A. (2007). Síntese e caracterização estrutural de complexos de oxorrênio (V) com ligantes O, O- e N, O- doadores. (Thesis). Universidade de Brasília. Retrieved from http://bdtd.bce.unb.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=1699
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Fernandes, André Gustavo de Araujo. “Síntese e caracterização estrutural de complexos de oxorrênio (V) com ligantes O, O- e N, O- doadores.” 2007. Thesis, Universidade de Brasília. Accessed January 17, 2021.
http://bdtd.bce.unb.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=1699.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Fernandes, André Gustavo de Araujo. “Síntese e caracterização estrutural de complexos de oxorrênio (V) com ligantes O, O- e N, O- doadores.” 2007. Web. 17 Jan 2021.
Vancouver:
Fernandes AGdA. Síntese e caracterização estrutural de complexos de oxorrênio (V) com ligantes O, O- e N, O- doadores. [Internet] [Thesis]. Universidade de Brasília; 2007. [cited 2021 Jan 17].
Available from: http://bdtd.bce.unb.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=1699.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Fernandes AGdA. Síntese e caracterização estrutural de complexos de oxorrênio (V) com ligantes O, O- e N, O- doadores. [Thesis]. Universidade de Brasília; 2007. Available from: http://bdtd.bce.unb.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=1699
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
12.
Neves, Larissa Lorena Evangelista das.
Benchmark para apoiar experimentos com testes funcionais de aplica??es m?veis.
Degree: 2019, Universidade Federal do Amazonas
URL: https://tede.ufam.edu.br/handle/tede/7429
► Com o aumento da import?ncia das aplica??es m?veis no cotidiano das pessoas, s?o necess?rias novas abordagens de Engenharia de Software para garantir a qualidade de…
(more)
▼ Com o aumento da import?ncia das aplica??es m?veis no cotidiano das pessoas, s?o necess?rias novas abordagens de Engenharia de Software para garantir a qualidade de tais aplica??es antes de sua disponibiliza??o ao usu?rio final, e isso inclui novas t?cnicas de teste de software. A pesquisa em teste de aplica??es m?veis precisa de diretrizes para melhorar os processos de valida??o, por meio de experimentos das t?cnicas propostas como resultados de pesquisas cient?ficas. No entanto, atualmente, n?o existe um benchmark detalhado e abrangente de aplica??es m?veis de refer?ncia para avaliar experimentalmente t?cnicas de teste para esta categoria de aplica??es. Os estudos encontrados mostram a falta de informa??es mais detalhadas das aplica??es. Com isso, a proposta deste trabalho ? a constru??o de um benchmark de aux?lio para pesquisador avaliar experimentalmente t?cnicas de teste em aplica??es m?veis composto por conjunto de aplica??es m?veis, scripts de teste e m?tricas referentes ?s aplica??es. Como resultado, foi utilizado um processo de sele??o de aplica??es m?veis para o benchmark. Ap?s sele??o do conjunto inicial de aplica??es que comp?e o benchmark, foram realizados dois estudos como forma de investigar se o benchmark proposto auxilia os pesquisadores em experimentos de t?cnicas de teste de aplica??es m?veis. As aplica??es foram selecionadas de acordo com suas caracter?sticas e as necessidades do experimento. Com isso, em ambos estudos foram utilizados 67% das aplica??es do benchmark.
With the increasing importance of mobile applications in people's daily lives, new software engineering approaches are required to ensure the quality of such mobile applications before their publication in application stores, and this includes new software testing techniques. Research on mobile application testing needs guidelines to improve the validation processes, through experiments, of techniques proposed as results of scientific research. However, there is currently no detailed and comprehensive benchmark of applications for evaluating experimental testing techniques for mobile applications. The studies found present the lack of more detailed information of the applications. Thus, this work proposes a benchmark of support to researchers which experimentally evaluates test techniques for mobile applications. This benchmark is composed of set of mobile applications, test scripts and metrics for applications. As a result of the definition, selection process was obtained for mobile application benchmark. After selection the initial benchmark, two studies were conducted to investigate if the proposed benchmark provides support to researchers to experimentally evaluate test techniques for mobile applications. The applications were selected according to their characteristics and the needs of experiment. Thus, in both studies, 67% of benchmark applications were used.
CAPES - Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior
Advisors/Committee Members: Dias Neto, Arilo Cl?udio, 70457433272, http://lattes.cnpq.br/9112415346373126, Feitosa, Eduardo Luzeiro, http://lattes.cnpq.br/5939944067207881, Endo, Andr? Takeshi, http://lattes.cnpq.br/4221336619791961, [email protected].
Subjects/Keywords: Engenharia de software; Aplica??es Web; Software - Desenvolvimento; Software de aplica??o; Software de aplica??o - Desenvolvimento; CI?NCIAS EXATAS E DA TERRA: CI?NCIA DA COMPUTA??O; Benchmark; Aplica??es M?veis; Teste de Aplica??es M?veis; Teste Funcional; Engenharia de Software Experimental
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APA ·
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MLA ·
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Export
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Manager
APA (6th Edition):
Neves, L. L. E. d. (2019). Benchmark para apoiar experimentos com testes funcionais de aplica??es m?veis. (Masters Thesis). Universidade Federal do Amazonas. Retrieved from https://tede.ufam.edu.br/handle/tede/7429
Chicago Manual of Style (16th Edition):
Neves, Larissa Lorena Evangelista das. “Benchmark para apoiar experimentos com testes funcionais de aplica??es m?veis.” 2019. Masters Thesis, Universidade Federal do Amazonas. Accessed January 17, 2021.
https://tede.ufam.edu.br/handle/tede/7429.
MLA Handbook (7th Edition):
Neves, Larissa Lorena Evangelista das. “Benchmark para apoiar experimentos com testes funcionais de aplica??es m?veis.” 2019. Web. 17 Jan 2021.
Vancouver:
Neves LLEd. Benchmark para apoiar experimentos com testes funcionais de aplica??es m?veis. [Internet] [Masters thesis]. Universidade Federal do Amazonas; 2019. [cited 2021 Jan 17].
Available from: https://tede.ufam.edu.br/handle/tede/7429.
Council of Science Editors:
Neves LLEd. Benchmark para apoiar experimentos com testes funcionais de aplica??es m?veis. [Masters Thesis]. Universidade Federal do Amazonas; 2019. Available from: https://tede.ufam.edu.br/handle/tede/7429
13.
Brimau, Fanny.
Rôle des odorants-binding protein dans le mécanisme de transduction olfactive : implication de modifications post-traductionnelles dynamiques dans la spécificité de liaison avec les ligands : Role of odorant-binding protein in the mechanism of olfactory transduction : implication of post-translationnal modification in the binding specificity with ligands.
Degree: Docteur es, Sciences de la Vie et de la Santé, 2010, Université François-Rabelais de Tours
URL: http://www.theses.fr/2010TOUR4038
► Les OBP sont des petites protéines solubles qui se lient avec des molécules odorantes et phéromonales. Le rôle des OBPs n’est pas complètement compris. Une…
(more)
▼ Les OBP sont des petites protéines solubles qui se lient avec des molécules odorantes et phéromonales. Le rôle des OBPs n’est pas complètement compris. Une hypothèse suggère que l’OBP solubilise et transporte les ligands aux récepteurs olfactifs et la liaison entre les molécules odorantes et l’OBP est non spécifique. Une autre hypothèse suggère que le complexe formé est une liaison spécifique entre une molécule odorante donnée et une OBP spécifique. Ce travail de thèse montre que les OBPs sont impliquées dans la première étape de la discrimination des odeurs. Dans un premier temps, nous avons montré l’implication de la Phe35 et la Tyr 82 dans la sortie du ligand par l’OBP. Dans un second temps, nous avons mis en évidence la présence de différentes isoformes d’OBP et de VEG qui diffèrent par les modifications post-traductionnelles (phosphorylation et GlcNAcylation) a la fois sur les protéines natives extraites de la muqueuse respiratoire et sur les protéines recombinantes produites par P.pastoris et CHO. Ces isoformes sont capables de discriminer des molécules odorantes et phéromonales. Les OBPs ne sont pas des transporteurs passifs car elles assurent un fin codage des molécules odorantes ou phéromonales avant l’interaction de ce complexe avec un récepteur spécifique.
OBPs are small soluble proteins that bind with odorant molecules and pheromones. The role of OBP is not completely understood. A hypothesis suggests that OBP solubilize and transport the ligands to olfactory receptors and the binding between odorant molecule and OBP is unspecific. An other hypothesis suggest that the complex formed is the specific binding between a given odorant molecule and a specific OBP. This work of thesis show that OBP are involved in the first step of odorant discrimination. Initially, we have showed the involvement of the Phe35 and Tyr 82 in the uptake of ligands by OBP. Second, we have given rise to the presence of various isoform of OBP and VEG that differ by post-translational modifications (phosphorylation and GlcNAcylation) both on natives proteins extract of respiratory mucosa and on recombinants proteins produce by P. pastoris and CHO. These isoforms are able to discriminate of odorant molecules and pheromones. OBPs are not passives carriers because they ensure a fine coding of odorant molecules and pheromones before interaction of this complex with specific receptor.
Advisors/Committee Members: Chemineau, Philippe (thesis director), Nagnan-Le Meillour, Patricia (thesis director).
Subjects/Keywords: BEMAD; O-N-Acetylglucosaminylation; Odorant-Binding protein; Von Ebner's gland protein
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APA ·
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APA (6th Edition):
Brimau, F. (2010). Rôle des odorants-binding protein dans le mécanisme de transduction olfactive : implication de modifications post-traductionnelles dynamiques dans la spécificité de liaison avec les ligands : Role of odorant-binding protein in the mechanism of olfactory transduction : implication of post-translationnal modification in the binding specificity with ligands. (Doctoral Dissertation). Université François-Rabelais de Tours. Retrieved from http://www.theses.fr/2010TOUR4038
Chicago Manual of Style (16th Edition):
Brimau, Fanny. “Rôle des odorants-binding protein dans le mécanisme de transduction olfactive : implication de modifications post-traductionnelles dynamiques dans la spécificité de liaison avec les ligands : Role of odorant-binding protein in the mechanism of olfactory transduction : implication of post-translationnal modification in the binding specificity with ligands.” 2010. Doctoral Dissertation, Université François-Rabelais de Tours. Accessed January 17, 2021.
http://www.theses.fr/2010TOUR4038.
MLA Handbook (7th Edition):
Brimau, Fanny. “Rôle des odorants-binding protein dans le mécanisme de transduction olfactive : implication de modifications post-traductionnelles dynamiques dans la spécificité de liaison avec les ligands : Role of odorant-binding protein in the mechanism of olfactory transduction : implication of post-translationnal modification in the binding specificity with ligands.” 2010. Web. 17 Jan 2021.
Vancouver:
Brimau F. Rôle des odorants-binding protein dans le mécanisme de transduction olfactive : implication de modifications post-traductionnelles dynamiques dans la spécificité de liaison avec les ligands : Role of odorant-binding protein in the mechanism of olfactory transduction : implication of post-translationnal modification in the binding specificity with ligands. [Internet] [Doctoral dissertation]. Université François-Rabelais de Tours; 2010. [cited 2021 Jan 17].
Available from: http://www.theses.fr/2010TOUR4038.
Council of Science Editors:
Brimau F. Rôle des odorants-binding protein dans le mécanisme de transduction olfactive : implication de modifications post-traductionnelles dynamiques dans la spécificité de liaison avec les ligands : Role of odorant-binding protein in the mechanism of olfactory transduction : implication of post-translationnal modification in the binding specificity with ligands. [Doctoral Dissertation]. Université François-Rabelais de Tours; 2010. Available from: http://www.theses.fr/2010TOUR4038
King Abdullah University of Science and Technology
14.
Elshewy, Ahmed M.
Efficient C-O and C-N bond forming cross-coupling reactions catalyzed by core-shell structured Cu/Cu2O nanowires.
Degree: 2013, King Abdullah University of Science and Technology
URL: http://hdl.handle.net/10754/306734
► Oxygen and Nitrogen containing compounds are of utmost importance due to their interesting and diverse biological activities. The construction of the C-O and C–N bonds…
(more)
▼ Oxygen and Nitrogen containing compounds are of utmost importance due to their interesting and diverse biological activities. The construction of the C-O and C–N bonds is of significance as it opens avenues for the introduction of ether and amine linkages in organic molecules. Despite significant advancements in this field, the construction of C-O and C–N bonds is still a major challenge for organic chemists, due to the involvement of harsh reaction conditions or the use of expensive catalysts or ligands in many cases. Thus, it is a challenge to develop alternative, milder, cheaper and more reproducible methodologies for the construction of these types of bonds. Herein, we introduce a new efficient ligand free catalytic system for C-O and C-N bond formation reactions.
Subjects/Keywords: cross-coupling; nano-wires; copper; C-O; C-N
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APA (6th Edition):
Elshewy, A. M. (2013). Efficient C-O and C-N bond forming cross-coupling reactions catalyzed by core-shell structured Cu/Cu2O nanowires. (Thesis). King Abdullah University of Science and Technology. Retrieved from http://hdl.handle.net/10754/306734
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Elshewy, Ahmed M. “Efficient C-O and C-N bond forming cross-coupling reactions catalyzed by core-shell structured Cu/Cu2O nanowires.” 2013. Thesis, King Abdullah University of Science and Technology. Accessed January 17, 2021.
http://hdl.handle.net/10754/306734.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Elshewy, Ahmed M. “Efficient C-O and C-N bond forming cross-coupling reactions catalyzed by core-shell structured Cu/Cu2O nanowires.” 2013. Web. 17 Jan 2021.
Vancouver:
Elshewy AM. Efficient C-O and C-N bond forming cross-coupling reactions catalyzed by core-shell structured Cu/Cu2O nanowires. [Internet] [Thesis]. King Abdullah University of Science and Technology; 2013. [cited 2021 Jan 17].
Available from: http://hdl.handle.net/10754/306734.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Elshewy AM. Efficient C-O and C-N bond forming cross-coupling reactions catalyzed by core-shell structured Cu/Cu2O nanowires. [Thesis]. King Abdullah University of Science and Technology; 2013. Available from: http://hdl.handle.net/10754/306734
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
University of Delaware
15.
Wang, Yiben.
Characterization and application of peptidoglycan O-acetyltransferase B utilizing N-acetylcysteamine derivatives.
Degree: PhD, University of Delaware, Department of Chemistry and Biochemistry, 2017, University of Delaware
URL: http://udspace.udel.edu/handle/19716/23030
► Bacteria have the natural ability to install protective post-synthetic modifications onto its bacterial peptidoglycan (PG); the coat that is woven into bacterial cell wall. Peptidoglycan…
(more)
▼ Bacteria have the natural ability to install protective post-synthetic modifications onto its bacterial peptidoglycan (PG); the coat that is woven into bacterial cell wall. Peptidoglycan
O-acetyltransferase B (PatB) catalyzes the
O-acetylation of peptidoglycan in Gram (–) bacteria, which aids in bacterial survival, as it prevents autolysins such as lysozyme from cleaving the peptidoglycan at the β-1,4-glycosidic bond between
N-acetylmuramic acid (NAM) and
N-acetylglucosamine (NAG). In this dissertation, the substrate promiscuity and mechanistic details of PatB’s acetylation function was explored and it was determined that PatB has substrate tolerance for bioorthgonal short
N-acetylcysteamine (SNAc) donors. Exploiting this lax specificity, a variety of functionality including azides and alkynes were installed on tri-
N-acetylglucosamine (NAG)3, a peptidoglycan mimic, as well as peptidoglycan isolated from various Gram (+) (Bacillus subtilis) and Gram (–) (Escherichia coli, Vibrio parahaemolyticus, and Pseudomonas putida) bacterial species. The bioorthogonal modifications were shown to protect the isolated peptidoglycan against lysozyme degradation in vitro. We further demonstrate that this post-synthetic modification of peptidoglycan can be extended to use click chemistry to fluorescently label the carbohydrate backbone of mature peptidoglycan in whole bacterial cells of Bacillus subtilis. Modifying peptidoglycan post-synthetically can aid in the development of antibiotics and immune modulators by expanding on the current understanding of how the bacterial peptidoglycan is processed by lytic enzymes presented in the innate immune system.
Advisors/Committee Members: Grimes, Catherine Leimkuhler.
Subjects/Keywords: Pure sciences; Bacteria labeling; N-acetylcysteamine; O-acetylation; PatB; Peptidoglycan
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APA ·
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CSE |
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APA (6th Edition):
Wang, Y. (2017). Characterization and application of peptidoglycan O-acetyltransferase B utilizing N-acetylcysteamine derivatives. (Doctoral Dissertation). University of Delaware. Retrieved from http://udspace.udel.edu/handle/19716/23030
Chicago Manual of Style (16th Edition):
Wang, Yiben. “Characterization and application of peptidoglycan O-acetyltransferase B utilizing N-acetylcysteamine derivatives.” 2017. Doctoral Dissertation, University of Delaware. Accessed January 17, 2021.
http://udspace.udel.edu/handle/19716/23030.
MLA Handbook (7th Edition):
Wang, Yiben. “Characterization and application of peptidoglycan O-acetyltransferase B utilizing N-acetylcysteamine derivatives.” 2017. Web. 17 Jan 2021.
Vancouver:
Wang Y. Characterization and application of peptidoglycan O-acetyltransferase B utilizing N-acetylcysteamine derivatives. [Internet] [Doctoral dissertation]. University of Delaware; 2017. [cited 2021 Jan 17].
Available from: http://udspace.udel.edu/handle/19716/23030.
Council of Science Editors:
Wang Y. Characterization and application of peptidoglycan O-acetyltransferase B utilizing N-acetylcysteamine derivatives. [Doctoral Dissertation]. University of Delaware; 2017. Available from: http://udspace.udel.edu/handle/19716/23030
University of Ottawa
16.
Derasp, Joshua.
Development of Cascade Reactions and Strategies for Carbon Centred Nucleophilic Additions to Blocked Isocyanates
.
Degree: 2019, University of Ottawa
URL: http://hdl.handle.net/10393/39326
► Isocyanates are invaluable bulk chemicals that play a central role in the synthesis of various polymers and provide a key platform for the synthesis of…
(more)
▼ Isocyanates are invaluable bulk chemicals that play a central role in the synthesis of various polymers and provide a key platform for the synthesis of nitrogen-containing molecules such as carbamates and ureas. Unfortunately, isocyanates suffer from high toxicity, low functional group tolerance, and a propensity to undergo deleterious side-reactions. Consequently, blocked (masked) isocyanate derivatives have been the subject of increased interest resulting from their reduced toxicity and exceptional control over isocyanate reactivity. This strategy has largely been relegated to the polymerization literature, although its use in the synthesis of complex urea and carbamate derivatives is well established in synthetic organic chemistry.
However, prominent gaps in the blocked isocyanate literature were clear at the outset of this research project. First and foremost, the development of heteroatom-substituted isocyanates, such as N- and O-substituted derivatives, remained relatively scarce despite their potential for the synthesis of important nitrogen-containing derivatives. Furthermore, the additions of carbon-centred nucleophiles on blocked N-, O-, and even C-substituted blocked isocyanates were exceedingly rare. Finally, the use of a blocking group strategy in catalytic transformations of isocyanates remained largely absent from the literature. This was particularly striking given the widespread development of catalytic transformations of isocyanates.
As such research efforts began focusing on furthering the development of blocked N-isocyanates as a vital platform for heterocyclic synthesis (chapter 2). Initially, the cascade reactivity of blocked N-iso(thio)cyanates was expanded to incorporate electrophiles such as alkynes (section 2.2). This readily provided access to imidazolone and thiazolidine products. Subsequently, the development of a cascade reaction providing access to 1,2,4-triazin-3(2H)-ones was explored (section 2.3). This provided the first examples of an N-isocyanate cascade which hinged on the use of acid catalysis. Moreover, insight into hydrazone isomerization was gained. Finally, these efforts culminated in the development of cascade reactions providing access to a rare class of 1,2,4-triazinones as well as 5-aminopyridazinones (section 2.4). This provided the first example of a cascade reaction involving a C-C bond formation onto a blocked N-isocyanate derivatives. Furthermore, this development was pivotal in re-focusing attention on the development of general strategies to achieve addition of carbon nucleophiles onto blocked isocyanate derivatives.
Towards this end, the development of two strategies to achieve carbon-centred nucleophilic additions on both blocked N- And O-isocyanates were developed (chapter 3). Inspiration from the isocyanate literature led to the development of carboxylic acids as formal carbon nucleophiles (section 3.2). This strategy was found to be quite general for the synthesis of hydroxamates from blocked O-isocyanates. Furthermore, encouraging results were generated…
Subjects/Keywords: Blocked isocyanates;
Amides;
N-isocyanates;
O-isocyanates;
hydroxamates;
hydrazide
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APA (6th Edition):
Derasp, J. (2019). Development of Cascade Reactions and Strategies for Carbon Centred Nucleophilic Additions to Blocked Isocyanates
. (Thesis). University of Ottawa. Retrieved from http://hdl.handle.net/10393/39326
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Derasp, Joshua. “Development of Cascade Reactions and Strategies for Carbon Centred Nucleophilic Additions to Blocked Isocyanates
.” 2019. Thesis, University of Ottawa. Accessed January 17, 2021.
http://hdl.handle.net/10393/39326.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Derasp, Joshua. “Development of Cascade Reactions and Strategies for Carbon Centred Nucleophilic Additions to Blocked Isocyanates
.” 2019. Web. 17 Jan 2021.
Vancouver:
Derasp J. Development of Cascade Reactions and Strategies for Carbon Centred Nucleophilic Additions to Blocked Isocyanates
. [Internet] [Thesis]. University of Ottawa; 2019. [cited 2021 Jan 17].
Available from: http://hdl.handle.net/10393/39326.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Derasp J. Development of Cascade Reactions and Strategies for Carbon Centred Nucleophilic Additions to Blocked Isocyanates
. [Thesis]. University of Ottawa; 2019. Available from: http://hdl.handle.net/10393/39326
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Universitat Autònoma de Barcelona
17.
Guerrero Hernández, Miguel.
Síntesis y caracterización de compuestos de coordinación con ligandos híbridos N,O-pirazol. Aplicaciones en Catálisis y Síntesis de Nanopartículas.
Degree: Departament de Química, 2010, Universitat Autònoma de Barcelona
URL: http://hdl.handle.net/10803/3323
► A parte de los artículos, esta memoria consta de cinco partes más: una introducción bibliográfica, unos objetivos, un capítulo de resultados y discusión, unas conclusiones…
(more)
▼ A parte de los artículos, esta memoria consta de cinco partes más: una introducció
n bibliográfica, unos objetivos, un capítulo de resultados y discusió
n, unas conclusiones y, por último, un compendio de todas las referencias bibliográficas consultadas para la elaboració
n de este trabajo. El grupo de investigació
n al que pertenezco comenzó los estudios de ligandos derivados del pirazol a principios de los años 90. Desde entonces, no se han parado las investigaciones, dando lugar a la síntesis de nuevos ligandos pirazólicos 3,5- disubstituidos potencialmente di-, tri- y tetradentados. En un principio se ensayó la reactividad de estos ligandos con metales de la primera serie de transició
n [Mn(II), Fe(III), Co(II), Ni(II), Cu(II)], obteniendo una gran diversidad estructural. En los últimos años se ha ampliado el número de ligandos y el número de complejos, utilizando metales de la segunda y tercera serie de transició
n [Pd(II) y Pt(II)]. Siguiendo con el estudio de ligandos derivados del pirazol, se abre una nueva línea de investigació
n dentro del grupo, basada en la síntesis y estudio de la química de coordinació
n de los ligandos pirazólicos substituidos en la posició
n 1 por grupos amina, fosfina, fosfinito, alcohol, éter, tiol, tioéter y tioéter-alcohol. Los metáles utilizados son básicamente de la segunda y tercera serie de transició
n [Ru(II), Rh(I), Pd(II) y Pt(II)]. Dentro de esta línea de investigació
n es donde está enmarcada esta Tesis que lleva por título: "Síntesis y caracterizació
n de compuestos de coordinació
n con ligandos híbridos
N,O¬pirazol. Aplicaciones en Catálisis y Síntesis de Nanopartículas."
Advisors/Committee Members: [email protected] (authoremail), true (authoremailshow), Pons Picart, Josefina (director), Ros Badosa, Josep (director).
Subjects/Keywords: N-O-pirazol; Síntesis de Nanopartículas; Catálisis; Ciències Experimentals; 54
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APA ·
Chicago ·
MLA ·
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CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Guerrero Hernández, M. (2010). Síntesis y caracterización de compuestos de coordinación con ligandos híbridos N,O-pirazol. Aplicaciones en Catálisis y Síntesis de Nanopartículas. (Thesis). Universitat Autònoma de Barcelona. Retrieved from http://hdl.handle.net/10803/3323
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Guerrero Hernández, Miguel. “Síntesis y caracterización de compuestos de coordinación con ligandos híbridos N,O-pirazol. Aplicaciones en Catálisis y Síntesis de Nanopartículas.” 2010. Thesis, Universitat Autònoma de Barcelona. Accessed January 17, 2021.
http://hdl.handle.net/10803/3323.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Guerrero Hernández, Miguel. “Síntesis y caracterización de compuestos de coordinación con ligandos híbridos N,O-pirazol. Aplicaciones en Catálisis y Síntesis de Nanopartículas.” 2010. Web. 17 Jan 2021.
Vancouver:
Guerrero Hernández M. Síntesis y caracterización de compuestos de coordinación con ligandos híbridos N,O-pirazol. Aplicaciones en Catálisis y Síntesis de Nanopartículas. [Internet] [Thesis]. Universitat Autònoma de Barcelona; 2010. [cited 2021 Jan 17].
Available from: http://hdl.handle.net/10803/3323.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Guerrero Hernández M. Síntesis y caracterización de compuestos de coordinación con ligandos híbridos N,O-pirazol. Aplicaciones en Catálisis y Síntesis de Nanopartículas. [Thesis]. Universitat Autònoma de Barcelona; 2010. Available from: http://hdl.handle.net/10803/3323
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
National University of Ireland – Galway
18.
Martin, Joanne C.
Computationally Guided Directed Evolution of O-GlcNAcase into a Reagent Specific for [beta]-O-GlcNAc
.
Degree: 2013, National University of Ireland – Galway
URL: http://hdl.handle.net/10379/4401
► Protein glycosylation with O-linked N-Acetylglucosamine (O-GlcNAc) is a post-translational modification of serine and threonine residues in nucleocytoplasmic proteins. Alterations in the glycosylation pattern of O-GlcNAc…
(more)
▼ Protein glycosylation with
O-linked
N-Acetylglucosamine (
O-GlcNAc) is a post-translational modification of serine and threonine residues in nucleocytoplasmic proteins. Alterations in the glycosylation pattern of
O-GlcNAc has been shown to play a role in many different cellular processes and
O-GlcNAcylation is often found at sites that are also known to be phosphorylated. Unlike phosphorylation, the addition and removal
O-GlcNAc are regulated by only two enzymes,
O-GlcNAc transferase (OGT) and
O-GlcNAc hydrolase (
O-GlcNAcase or OGA). So far, no obvious consensus sequence has been found for sites of
O-GlcNAcylation; additionally,
O-GlcNAcase acts on all
O-GlcNAcylated proteins, seemingly independent of their sequence. Despite the importance of this modification, very little is known about the structural relationship between these enzymes and their substrates. Nor is it clear, how only a single hydrolase is capable of removing
O-GlcNAc from all GlcNAcylated proteins, independent of the protein sequence.
Here a combination of computational and experimental techniques is employed to develop an understanding of the interactions between an inactive point mutant of OGA and its substrate, in an aim to designing an OGA-based receptor with enhanced affinity for
O-GlcNAc. The key interactions involved in binding have been identified computationally, and are separated into residues which are directly responsible for the specificity of the complex (hot residues) and those whose mutation may increase the affinity (tepid residues). An inactive human OGA, which was engineered using site directed mutagenesis to knock out the nucleophile, was used to construct a combinatorial library in bacteriophage by saturation mutagenesis of the tepid residues. This library has been screened leading to the discovery of a single clone showing high affinity and specificity for
O-GlcNAc. Reagents of this type are termed Lectenz®, and may be important diagnostic tools for the detection of enzyme substrates, such as
O-GlcNAcylated proteins.
In addition, five models of
O-GlcNAcylated peptides in complex with a bacterial OGA were generated and assessed in terms of conformational dynamics and binding contributions in an aim to understand how OGA recognizes
O-GlcNAc in situ. The results show that each of the five glycopeptides bind to OGA in a similar fashion, forming OGA-peptide interactions primarily, but not exclusively, with peptide backbone atoms, thus explaining the lack of sensitivity to peptide sequence. Nonetheless, differences in peptide sequences, particularly at the -1 to -4 positions, lead to variations in predicted affinity, consistent with observed experimental variations in enzyme kinetics. The potential exists therefore to employ the present analysis to guide the development glycopeptide-specific inhibitors, or conversely, the conversion of OGA into reagents that could target specific
O-GlcNAcylated peptide sequences.
Advisors/Committee Members: Woods, Robert J (advisor).
Subjects/Keywords: Glycobiology;
Molecular dynamics;
O-linked N acetyl-glucosamine (O-GlcNAc);
Protein glycosylation;
Molecular recognition;
[Beta]-N-acetylglucosaminidase (O-GlcNAcase);
Department of Chemistry
Record Details
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Martin, J. C. (2013). Computationally Guided Directed Evolution of O-GlcNAcase into a Reagent Specific for [beta]-O-GlcNAc
. (Thesis). National University of Ireland – Galway. Retrieved from http://hdl.handle.net/10379/4401
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Martin, Joanne C. “Computationally Guided Directed Evolution of O-GlcNAcase into a Reagent Specific for [beta]-O-GlcNAc
.” 2013. Thesis, National University of Ireland – Galway. Accessed January 17, 2021.
http://hdl.handle.net/10379/4401.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Martin, Joanne C. “Computationally Guided Directed Evolution of O-GlcNAcase into a Reagent Specific for [beta]-O-GlcNAc
.” 2013. Web. 17 Jan 2021.
Vancouver:
Martin JC. Computationally Guided Directed Evolution of O-GlcNAcase into a Reagent Specific for [beta]-O-GlcNAc
. [Internet] [Thesis]. National University of Ireland – Galway; 2013. [cited 2021 Jan 17].
Available from: http://hdl.handle.net/10379/4401.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Martin JC. Computationally Guided Directed Evolution of O-GlcNAcase into a Reagent Specific for [beta]-O-GlcNAc
. [Thesis]. National University of Ireland – Galway; 2013. Available from: http://hdl.handle.net/10379/4401
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
19.
Menezes, Reinaldo Oliveira; http://lattes.cnpq.br/7473472581798712.
Filosofia e Educa??o Especial: An?lise do PPC de Filosofia da UFAM no movimento da Educa??o Inclusiva.
Degree: 2020, Universidade Federal do Amazonas
URL: https://tede.ufam.edu.br/handle/tede/8003
► Este trabalho teve como objetivo verificar se o tema Educa??o Especial tem se efetivado no Projeto Pedag?gico do Curso de Filosofia da Universidade Federal do…
(more)
▼ Este trabalho teve como objetivo verificar se
o tema Educa??
o Especial tem se efetivado no Projeto Pedag?gico do Curso de Filosofia da Universidade Federal do Amazonas (UFAM), comparando com outras Universidades Federais da regi?
o norte com intuito de compreender como a UFAM tem constru?do
o PPC de Filosofia para atender ? forma??
o inicial de professores de Filosofia sobre a educa??
o inclusiva, a fim de terem, ao final da licenciatura, uma forma??
o que, de fato, os possibilite
o atendimento aos alunos com qualquer tipo de necessidade especial.
O movimento da educa??
o inclusiva via Educa??
o Especial tem sido
o centro das discuss?es nas agendas das pol?ticas p?blicas educacionais no Brasil e no mundo e que, desde as d?cadas de 1990 e 1994, respectivamente com as Declara??es de Jomtien ? que trata sobre Educa??
o para Todos e da Salamanca ? que aborda a Educa??
o Especial na perspectiva da inclus?
o,
o Estado vem assumindo
o compromisso de promover
o acesso das pessoas com defici?ncia na Educa??
o B?sica e garantir a perman?ncia delas no processo educacional, pois sabemos que a Educa??
o Especial no processo de forma??
o inicial tem sido um dos desafios para
o sucesso da implementa??
o da pol?tica de Educa??
o inclusiva. Para a realiza??
o da pesquisa, a metodologia foi assim definida: quanto aos objetivos, ? explorat?ria, quanto ? abordagem, ? qualitativa; quanto ao m?todo de abordagem, utilizou-se
o hermen?utico-dial?tico e, quanto ao m?todo de procedimento,
o bibliogr?fico,
o documental e
o comparativo, sendo
o corpus de estudo composto pelo PPC da UFAM, pelo PPC da UFAC e leis brasileiras sobre Educa??
o Especial. Optamos pelo m?todo hermen?utico-dial?tico por nos permitir
o aprofundamento da compreens?
o e da interpreta??
o dos marcos legais e das literaturas que tratam da Educa??
o Especial na perspectiva da inclus?
o e da forma??
o de professores em Filosofia.
O respectivo estudo nos apontou que, mesmo com os marcos legais sobre a Educa??
o Especial na perspectiva da inclus?
o escolar, a matriz curricular de Filosofia da UFAM, em parte,
n?
o tem acompanhado as mudan?as das Leis de inclus?
o, dando aten??
o somente para uma parcela do p?blico-alvo da Educa??
o Especial, que s?
o as pessoas com surdez, mediante a oferta da disciplina LIBRAS. Assim, falta investimento na forma??
o dos futuros professores de Filosofia no que diz respeito aos conhecimentos sobre as demais necessidades especiais. Nota-se que somente a oferta de LIBRAS
n?
o supre a necessidade de capacitar
o futuro professor de Filosofia para compreender as especificidades das necessidades educacionais especiais, as quais englobam defici?ncia, transtorno globais do desenvolvimento e altas habilidades ou superdotado. Estas quest?es deveriam ser contempladas no PPC de Filosofia para que a forma??
o do futuro docente seja completa e este compreenda ?s necessidades desses alunos, bem como os m?todos de ensino-aprendizagem para atend?-los satisfatoriamente na pr?tica de sala de aula no Ensino Regular. Quanto ao PPC de Filosofia da UFAC, tem apresentado um curr?culo atualizado e…
Advisors/Committee Members: Simas, Hellen Cristina Pican?o, http://lattes.cnpq.br/0232506734130510, Ferreira, L?cio Fernandes, Oliveira, Dami?o Bezerra.
Subjects/Keywords: Educa??o inclusiva - Forma??o; Inclus?o escolar - Forma??o; CNPQ::CIENCIAS HUMANAS::EDUCACAO; Filosofia; Educa??o Especial; Inclus?o escolar; Projeto Pedag?gico do Curso; Forma??o inicial; Pholosophy; Special Education; School Inclusion; Pedagogical Course Project; Initial Education; Filosof?a; Educaci?n Especial; Inclusi?n escolar; Proyecto Pedag?gico del curso; Formaci?n inicial
Record Details
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Record Details
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Menezes, R. O. h. c. b. (2020). Filosofia e Educa??o Especial: An?lise do PPC de Filosofia da UFAM no movimento da Educa??o Inclusiva. (Masters Thesis). Universidade Federal do Amazonas. Retrieved from https://tede.ufam.edu.br/handle/tede/8003
Chicago Manual of Style (16th Edition):
Menezes, Reinaldo Oliveira; http://lattes cnpq br/7473472581798712. “Filosofia e Educa??o Especial: An?lise do PPC de Filosofia da UFAM no movimento da Educa??o Inclusiva.” 2020. Masters Thesis, Universidade Federal do Amazonas. Accessed January 17, 2021.
https://tede.ufam.edu.br/handle/tede/8003.
MLA Handbook (7th Edition):
Menezes, Reinaldo Oliveira; http://lattes cnpq br/7473472581798712. “Filosofia e Educa??o Especial: An?lise do PPC de Filosofia da UFAM no movimento da Educa??o Inclusiva.” 2020. Web. 17 Jan 2021.
Vancouver:
Menezes ROhcb. Filosofia e Educa??o Especial: An?lise do PPC de Filosofia da UFAM no movimento da Educa??o Inclusiva. [Internet] [Masters thesis]. Universidade Federal do Amazonas; 2020. [cited 2021 Jan 17].
Available from: https://tede.ufam.edu.br/handle/tede/8003.
Council of Science Editors:
Menezes ROhcb. Filosofia e Educa??o Especial: An?lise do PPC de Filosofia da UFAM no movimento da Educa??o Inclusiva. [Masters Thesis]. Universidade Federal do Amazonas; 2020. Available from: https://tede.ufam.edu.br/handle/tede/8003
20.
OLIVEIRA, João Andrade de.
O ensino aprendizagem da matemática nas 4ª séries do ensino fundamental das escolas públicas: estudo de caso do Ibura
.
Degree: 2005, Universidade Federal de Pernambuco
URL: http://repositorio.ufpe.br/handle/123456789/5929
► Esta dissertação propõe-se a ser um estudo avaliativo e comparativo do ensinoaprendizagem da Matemática nas 4ª séries do Ensino Fundamental das Escolas Municipais e Estaduais…
(more)
▼ Esta dissertaçã
o propõe-se a ser um estudo avaliativo e comparativo do ensinoaprendizagem
da Matemática nas 4ª séries do Ensino Fundamental das Escolas Municipais e
Estaduais do Recife: estudo de caso do Ibura.
O objetivo principal é verificar e analisar as
causas do baixo rendimento escolar do ensino-aprendizagem da Matemática das escolas
municipais e estaduais.
A pesquisa foi conduzida através de entrevistas, com questionário aplicado aos
professores para identificar a proposta de trabalho que está sendo vivenciada em cada sala de
aula. Verificou-se, porém, que muitas vezes, essas propostas que fazem
o ensino acontecer
ainda nã
o estã
o sendo utilizadas devidamente. Além disso, foi aplicado um
teste avaliativo
sobre
o uso e a aplicaçã
o das quatro operações básicas, aos alunos, realizadas em 10 salas de
aula das escolas estudadas. Logo, observou-se que muitas vezes a Matemática ensinada é uma
arrumaçã
o de regras prontas, exigindo em determinados momentos, uma grande quantidade
de memorizaçã
o para armazenar dados, regras, textos e formulários.
Mediante essas considerações, aplicou-se
o teste de FISHER ao resultado dos valores
do Enfoque Pedagógico e identificou-se que os professores ainda utilizam indevidamente as
propostas do Ensino-Aprendizagem Tradicional da Matemática, nã
o incorporando totalmente
as vantagens da Nova Proposta do ensino Aprendizagem da Matemática.
Entã
o,
o autor deseja que este trabalho possa contribuir na formaçã
o dos Educadores e
Educandos e que os conduzam a pensar, refletir, resumir, analisar e aplicar suas sugestões de
proposta Ensino-aprendizagem, porém, de modo que possa somar valores a projetos
educativos
Advisors/Committee Members: SICSU, Abraham Benzaquen (advisor).
Subjects/Keywords: Ensino-Aprendizagem;
Operações Fundamentais;
O teste de FISHER
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
OLIVEIRA, J. A. d. (2005). O ensino aprendizagem da matemática nas 4ª séries do ensino fundamental das escolas públicas: estudo de caso do Ibura
. (Thesis). Universidade Federal de Pernambuco. Retrieved from http://repositorio.ufpe.br/handle/123456789/5929
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
OLIVEIRA, João Andrade de. “O ensino aprendizagem da matemática nas 4ª séries do ensino fundamental das escolas públicas: estudo de caso do Ibura
.” 2005. Thesis, Universidade Federal de Pernambuco. Accessed January 17, 2021.
http://repositorio.ufpe.br/handle/123456789/5929.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
OLIVEIRA, João Andrade de. “O ensino aprendizagem da matemática nas 4ª séries do ensino fundamental das escolas públicas: estudo de caso do Ibura
.” 2005. Web. 17 Jan 2021.
Vancouver:
OLIVEIRA JAd. O ensino aprendizagem da matemática nas 4ª séries do ensino fundamental das escolas públicas: estudo de caso do Ibura
. [Internet] [Thesis]. Universidade Federal de Pernambuco; 2005. [cited 2021 Jan 17].
Available from: http://repositorio.ufpe.br/handle/123456789/5929.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
OLIVEIRA JAd. O ensino aprendizagem da matemática nas 4ª séries do ensino fundamental das escolas públicas: estudo de caso do Ibura
. [Thesis]. Universidade Federal de Pernambuco; 2005. Available from: http://repositorio.ufpe.br/handle/123456789/5929
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
University of Pretoria
21.
McLagan, Toni Lisa.
Re[growth] :
a development of social capital through food network
accessibility.
Degree: MArch (Prof), Architecture, 2016, University of Pretoria
URL: http://hdl.handle.net/2263/60188
► Die verhandeling is gerig op die toenemende globale kwessie van ons land se voedselonsekerheid en die faktore wat daartoe bydra. Dit ondersoek die rol wat…
(more)
▼ Die verhandeling is gerig op die toenemende globale
kwessie van ons land se voedselonsekerheid en die
faktore wat
daartoe bydra.
Dit ondersoek die rol wat argitektuur kan speel as
'
n
sistemiese instrument (in die vorm van '
n gastronomiese
kwartaal) vir die her[groei] van '
n hoogs omstrede
kwessie. Deur
die identifisering van globale en plaaslike
omstandighede word
voedselsekerheid bemagtiging
ontwikkel deur die integrasie van
sosio-ekonomiese
stelsels wat optree as punte van akupunktuur om
kontekstuele omstandighede te verbeter.
Deur '
n nuut gevormde
argitektoniese benadering
waardeur kos en die toeganklikheid
daarvan die basis
vorm van sosiale inklusiwiteit, word verskeie
mense in die
samelewing bemagtig deur van plaaslike ondersteuning
gebruik te maak. Plaaslike ondersteuning is van kardinale
belang
vir die groei en bemagtiging van '
n gemeenskap,
wat '
n positiewe
impak op die algehele stedelike
moraliteit of weefsel het deur die
voorsiening van '
n meer
inklusiewe omgewing vir die bemagtiging
van daardie
V. gemeenskap.
Advisors/Committee Members: Combrinck, Carin (advisor).
Subjects/Keywords: UCTD; F o o d i n s
e c u r i t y; In f o r m a l
t r a d e; Food
network; A s t r o n o
m i c q u a r t e r
Record Details
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Record Details
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
McLagan, T. L. (2016). Re[growth] :
a development of social capital through food network
accessibility. (Masters Thesis). University of Pretoria. Retrieved from http://hdl.handle.net/2263/60188
Chicago Manual of Style (16th Edition):
McLagan, Toni Lisa. “Re[growth] :
a development of social capital through food network
accessibility.” 2016. Masters Thesis, University of Pretoria. Accessed January 17, 2021.
http://hdl.handle.net/2263/60188.
MLA Handbook (7th Edition):
McLagan, Toni Lisa. “Re[growth] :
a development of social capital through food network
accessibility.” 2016. Web. 17 Jan 2021.
Vancouver:
McLagan TL. Re[growth] :
a development of social capital through food network
accessibility. [Internet] [Masters thesis]. University of Pretoria; 2016. [cited 2021 Jan 17].
Available from: http://hdl.handle.net/2263/60188.
Council of Science Editors:
McLagan TL. Re[growth] :
a development of social capital through food network
accessibility. [Masters Thesis]. University of Pretoria; 2016. Available from: http://hdl.handle.net/2263/60188
22.
Araújo, Ana Luísa Alves.
Bem-estar subjectivo em crianças : relação entre os autorrelatos das crianças e os relatos dos pais e das mães.
Degree: 2017, RCAAP
URL: https://www.rcaap.pt/detail.jsp?id=oai:repositorio.ulusiada.pt:11067/3704
► Resumo: O Bem-Estar Subjetivo tem sido alvo de um crescente interesse para investigação em Psicologia. O estudo do Bem-Estar Subjetivo como um construto amplo e…
(more)
▼ Resumo:
O Bem-Estar Subjetivo tem sido alvo de um crescente interesse para investigação em Psicologia. O estudo do Bem-Estar Subjetivo como um construto amplo e multidimensional, refere-se àquilo que as pessoas sentem e pensam sobre a sua própria vida, envolvendo respostas emocionais e domínios de satisfação. São poucas as investigações que procuram perceber a forma como os pais percecionam o bem-estar dos próprios filhos. Desta forma, a presente investigação visou avaliar o Bem-Estar Subjetivo autorrelatado pelas crianças, bem como a perceção dos pais e a perceção das mães sobre
o Bem-Estar Subjetivo dos filhos. Participaram neste estudo 1482 crianças (739 raparigas e 741 rapazes) com idades compreendidas entre os 6 e os 12 anos e respetivos pais e mães.
As diferentes componentes do Bem-Estar Subjetivo foram avaliadas, tendo em conta escalas de auto e hétero relato: Kidscreen 10, Escala de Tonalidade Emocional, Escala Breve de Satisfação com o Suporte Social e Escala Breve de Satisfação com a Vida. A recolha dos dados zelou pela salvaguarda da integridade psicológica dos alunos e respetivos pais e mães. Os principais resultados permitem-nos afirmar que existem diferenças significativas entre o Bem-Estar Subjetivo autorrelatado pelas crianças e os relatos dos pais e das mães relativamente ao Bem-Estar Subjetivo das crianças. Contudo, observou-se a existência de uma associação positiva entre os autorrelatos das crianças e a perceção dos pais e das mães sobre o Bem-Estar Subjetivo dos filhos. Verificou-se ainda um acordo entre o autorrelatos das crianças e a perceção dos pais e das mães sobre o Bem-
Estar Subjetivo. Este estudo promoveu uma melhor compreensão do Bem-Estar Subjetivo das crianças Portuguesas assim como permitiu perceber de que forma tanto os pais como as mães percecionam o bem-estar dos seus filhos.
The Subjective Well-Being has been the target of a growing interest for research in Psychology. The study of Subjective Well-Being as a broad, multidimensional construct, refers to what people feel and think about their own lives, involving emotional responses and domains of satisfaction. There are few investigations that seek to understand how parents perceive the well-being of their children. In this way, the present investigation
aimed to evaluate the Subjective Well-Being self-reported by the children, as well as the father's and mother's perception of the Subjective Well-Being of their children. A total of 1482 children (739 girls and 741 boys) aged 6 to 12 years and their fathers and mothers participated in the study. The different components of Subjective Well-Being were evaluated, taking into account self-reported and straightforward scales: Kidscreen 10, Emotional Tone Scale, Brief Scale of Satisfaction with Social Support and Brief Scale of Satisfaction with Life. The collection of data ensured the safeguarding of the psychological integrity of students and their parents. The main results allow us to affirm that there are significant differences between the Subjective Well-Being self-reported by…
Advisors/Committee Members: Moreira, Paulo Alexandre Soares.
Subjects/Keywords: Psicologia; Psicologia clínica; Bem-estar - Aspectos psicológicos; Avaliação psicológica; Teste Psicológico - Escala breve de satisfação com a vida (EBVS); este Psicológico - Escala Breve de Satisfação com o Suporte Social (EBSSS); Teste Psicológico - Escala de Tonalidade Emociona; Teste Psicológico - Escala breve de saúde mental (KIDSCREEN 10)
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APA (6th Edition):
Araújo, A. L. A. (2017). Bem-estar subjectivo em crianças : relação entre os autorrelatos das crianças e os relatos dos pais e das mães. (Thesis). RCAAP. Retrieved from https://www.rcaap.pt/detail.jsp?id=oai:repositorio.ulusiada.pt:11067/3704
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Araújo, Ana Luísa Alves. “Bem-estar subjectivo em crianças : relação entre os autorrelatos das crianças e os relatos dos pais e das mães.” 2017. Thesis, RCAAP. Accessed January 17, 2021.
https://www.rcaap.pt/detail.jsp?id=oai:repositorio.ulusiada.pt:11067/3704.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Araújo, Ana Luísa Alves. “Bem-estar subjectivo em crianças : relação entre os autorrelatos das crianças e os relatos dos pais e das mães.” 2017. Web. 17 Jan 2021.
Vancouver:
Araújo ALA. Bem-estar subjectivo em crianças : relação entre os autorrelatos das crianças e os relatos dos pais e das mães. [Internet] [Thesis]. RCAAP; 2017. [cited 2021 Jan 17].
Available from: https://www.rcaap.pt/detail.jsp?id=oai:repositorio.ulusiada.pt:11067/3704.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Araújo ALA. Bem-estar subjectivo em crianças : relação entre os autorrelatos das crianças e os relatos dos pais e das mães. [Thesis]. RCAAP; 2017. Available from: https://www.rcaap.pt/detail.jsp?id=oai:repositorio.ulusiada.pt:11067/3704
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
23.
Younis, Vincent.
Att vara välkomen men ändå inte : “Povertyisthemotherofcrime”/MarcusAurelius.
Degree: Care and Social Welfare, 2017, Mälardalen University
URL: http://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-38412
► Studien undersöker invånare och verksammas upplevelser av ett, enligt en rapport frånunderrättelseenheten, utsatt bostadsområde i Västerås. För att besvara frågeställningen har vigenomfört 14 intervjuer…
(more)
▼ Studien undersöker invånare och verksammas upplevelser av ett, enligt en rapport frånunderrättelseenheten, utsatt bostadsområde i Västerås. För att besvara frågeställningen har vigenomfört 14 intervjuer varav 5 var semistrukturerade och resterande var ostrukturerade. Vihar även genomfört 6 observationer, där samtliga var icke deltagande observationer. Dåmålsättningen var att undersöka så förutsättningslöst som möjligt har vi använt oss av BarneyGlasers variant av grundad teori som metodologiskt angreppssätt. Tidigare forskning som vibelyser är delade i tre teman: Segregation, familjestrukturer och sysselsättning. En teorisom är grundad i data presenteras i resultatdelen och beskriver det som sker i Bäckby.Studiens teoretiska referensramar är Erving Goffmans teori om stigma, Howard. S. Beckersteori om avvikande samt Giorgio Agambens teori om undantag och belägring som fungerarsom en komplettering till förståelsen av hur det är i ett utsatt bostadsområde. Slutsatsernavisar att det är en handfull ungdomar som står för oron som sker i Bäckby och dess handlingarmöjliggörs på grund av misslyckade strukturella åtgärder. De förhållanden vi har funnitavgörande för trygghets upplevelse i Bäckby är inte endast att ungdomar behöversysselsättning, utan det behövs även en spridning av människor med utländsk bakgrund blandetniska svenskar och förebyggande åtgärder från externa aktörer.
Subjects/Keywords: u n g d o m a r; b o s t a d s o m r å d e; s y s s e l s ä t t n i n g; s p r i d n i n g; b r o t t; t r y g g h e t; Social Sciences; Samhällsvetenskap
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APA ·
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Manager
APA (6th Edition):
Younis, V. (2017). Att vara välkomen men ändå inte : “Povertyisthemotherofcrime”/MarcusAurelius. (Thesis). Mälardalen University. Retrieved from http://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-38412
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Younis, Vincent. “Att vara välkomen men ändå inte : “Povertyisthemotherofcrime”/MarcusAurelius.” 2017. Thesis, Mälardalen University. Accessed January 17, 2021.
http://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-38412.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Younis, Vincent. “Att vara välkomen men ändå inte : “Povertyisthemotherofcrime”/MarcusAurelius.” 2017. Web. 17 Jan 2021.
Vancouver:
Younis V. Att vara välkomen men ändå inte : “Povertyisthemotherofcrime”/MarcusAurelius. [Internet] [Thesis]. Mälardalen University; 2017. [cited 2021 Jan 17].
Available from: http://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-38412.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Younis V. Att vara välkomen men ändå inte : “Povertyisthemotherofcrime”/MarcusAurelius. [Thesis]. Mälardalen University; 2017. Available from: http://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-38412
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
24.
Saunier, Karine Aguiar de Sousa.
N?o mate a mata: vis?es ambientais precursoras na obra musical de Adelson Santos.
Degree: 2017, Universidade Federal do Amazonas
URL: https://tede.ufam.edu.br/handle/tede/6342
► H? pelo menos 35 anos a composi??o Argumento tornou-se uma das mais conhecidas obras do cancioneiro amazonense pelo nome de N?o mate a mata, desde…
(more)
▼ H? pelo menos 35 anos a composi??o Argumento tornou-se uma das mais conhecidas obras do cancioneiro amazonense pelo nome de N?o mate a mata, desde que recebeu seu primeiro registro fonogr?fico no LP Compacto Simples Adelson (1980) e passou ser tocada nas principais r?dios amazonenses. De autoria do cantautor manauara Adelson Santos, a obra ? reconhecida por artistas e apreciadores da m?sica local como uma verdadeira ode ? conserva??o ambiental na Amaz?nia. A can??o atingiu reconhecimento social apenas em 1980, posicionando Adelson Santos como o mais representativo ?cantautor ecol?gico? amazonense. O contexto sociocultural no qual este artista come?ou a refletir sobre a problem?tica ambiental por meio de sua m?sica, esteve marcado por uma s?rie de eventos importantes para a consolida??o do Movimento Ecol?gico em todo o mundo. Em seus mais de 40 anos de cria??o, a referida pe?a musical tem demonstrado seu car?ter precursor e atemporal, metamorfoseando-se em arranjos desde o Boi-bumb? ao Jazz instrumental, de releituras de realizadas por artistas de diversas gera??es e segmentos musicais distintos no Estado do Amazonas. Com a realiza??o deste estudo, objetivamos muito mais do que realizar apenas um invent?rio das can??es ecol?gicas de Adelson Santos, analisar sob a perspectiva da etnomusicologia e da antropologia da performance musical sua mais importante obra Argumento, ou simplesmente, reconstruir tra?os configurativos de sua biografia para comprovar a sua condi??o de sujeito ecol?gico. A cr?tica radical ? crise ambiental contida na obra de Adelson Santos ? vista por n?s como mais uma possibilidade para reafirmar a posi??o de centralidade da Cultura na discuss?o sobre o Desenvolvimento Sustent?vel em todo o mundo no p?s-2015. Ao buscarmos estabelecer uma interface entre a produ??o de sons musicais, natureza e sustentabilidade, estamos tamb?m criando um espa?o para a valoriza??o de m?ltiplos discursos e saberes, bem como dos in?meros sujeitos ecol?gicos existentes fora de uma tradi??o naturalista, uma vez que a Ecologia, nos dias atuais, se assume como ideia migrante, encontrando-se em posi??o bastante pr?xima aos movimentos sociais. Ao revelarmos estes sujeitos ecol?gicos fora das ?reas do conhecimento de tradi??o naturalista, queremos provocar uma discuss?o acerca voca??o interdisciplinar e agregadora das Ci?ncias do Ambiente, bem como, da pr?pria M?sica a partir da nov?ssima orienta??o te?rica proposta pela Ecomusicologia e, tamb?m, do j? consolidado campo da Etnomusicologia. Fomentamos com isto uma discuss?o acerca da ecologia de saberes e, ainda, novas perspectivas para a reforma do pensamento cient?fico e a desconstru??o dos velhos modelos da tecnoci?ncia que ainda impedem a exist?ncia de uma reciprocidade entre as diversas formas de reproduzir e conhecer o mundo em que vivemos.
For at least 35 years, Argumento has become one of the best-known works of the Amazonian songbook by the name of Nao Mate a mata, since it received its first record in the Simple Compact LP Adelson (1980) and was played in the main…
Advisors/Committee Members: Witkoski, Antonio Carlos, 517.866.300-44, http://lattes.cnpq.br/1111807488532588, Mesquita, Bernardo Thiago Paiva, Montardo, Deise Lucy, Monteiro, Gilson Vieira, Higuchi, Maria Ines Gasparetto, Braga, S?rgio Ivan Gil, [email protected].
Subjects/Keywords: Adelson Santos; N?o mate a mata - Obra musical; Ecomusicologia; Sustentabilidade; Conserva??o Ambiental; CI?NCIAS AGR?RIAS
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Saunier, K. A. d. S. (2017). N?o mate a mata: vis?es ambientais precursoras na obra musical de Adelson Santos. (Masters Thesis). Universidade Federal do Amazonas. Retrieved from https://tede.ufam.edu.br/handle/tede/6342
Chicago Manual of Style (16th Edition):
Saunier, Karine Aguiar de Sousa. “N?o mate a mata: vis?es ambientais precursoras na obra musical de Adelson Santos.” 2017. Masters Thesis, Universidade Federal do Amazonas. Accessed January 17, 2021.
https://tede.ufam.edu.br/handle/tede/6342.
MLA Handbook (7th Edition):
Saunier, Karine Aguiar de Sousa. “N?o mate a mata: vis?es ambientais precursoras na obra musical de Adelson Santos.” 2017. Web. 17 Jan 2021.
Vancouver:
Saunier KAdS. N?o mate a mata: vis?es ambientais precursoras na obra musical de Adelson Santos. [Internet] [Masters thesis]. Universidade Federal do Amazonas; 2017. [cited 2021 Jan 17].
Available from: https://tede.ufam.edu.br/handle/tede/6342.
Council of Science Editors:
Saunier KAdS. N?o mate a mata: vis?es ambientais precursoras na obra musical de Adelson Santos. [Masters Thesis]. Universidade Federal do Amazonas; 2017. Available from: https://tede.ufam.edu.br/handle/tede/6342
University of Georgia
25.
Lim, Jae-Min.
Secretome and glycome of mammalian adipocytes under insulin resistant conditions.
Degree: 2014, University of Georgia
URL: http://hdl.handle.net/10724/25543
► Insulin resistance defines the metabolic syndrome and precedes type 2 diabetes, thus is considered as the hallmark for type 2 diabetes. Prolonged hyperglycemia and hyperinsulinemia…
(more)
▼ Insulin resistance defines the metabolic syndrome and precedes type 2 diabetes, thus is considered as the hallmark for type 2 diabetes. Prolonged hyperglycemia and hyperinsulinemia are both required for the development of classical insulin
resistance. In recent years, accumulative evidence has established that elevated O-GlcNAc levels via either genetic or pharmacological methods lead to insulin resistance in both cultured adipocytes and animal models. Adipocytes, besides being a major
site for energy storage, are endocrine in nature and secrete a variety of proteins (adipocytokines) that can modulate insulin sensitivity, hypertension, food intake, and general energy homeostasis. The link between O-GlcNAc levels, insulin resistance,
and adipocytokine secretion is further explored in this dissertation. First, by using immortalized and primary rodent adipocytes, the secreted proteome of differentiated adipocytes under insulin responsive and two insulin resistant conditions is
explicitly elucidated via shotgun proteomics leading to the identification of 97 and 203 secreted proteins, respectively. More than 80 N-linked glycosylation sites on adipocytokines released by these adipocytes were also mapped. Moreover, we took a step
further to address the quantitative secretome of human primary adipocytes with the same technique. Of the 190 secreted proteins identified, we report 20 up-regulated and 6 down-regulated proteins detected in both insulin resistant conditions. Moreover,
we applied glycomic techniques to examine (1) the N-linked sites from the pool of secreted proteins and (2) the characterization and relative abundance of complex N- and O-glycans released from adipocytes exposed to different conditions. We identified 91
Nglycosylation sites on the secreted proteins derived from 51 proteins, as well as 155 and 29 released N- and O-glycans respectively. There were moderate alterations in the observed N- and O-linked glycans under the different conditions considered. In
short, our studies have provided a list of adipocytokines whose secreted levels vary under insulin resistant conditions. These proteins bear the potential to be prognostic/diagnostic biomarkers for the detection of metabolic syndrome and type 2 diabetes.
Also, comparing the results complied from both classical and non-canonical insulin resistance provides further insights for the role of the O-GlcNAc modification on intracellular proteins in the disease progression of type 2 diabetes.
Subjects/Keywords: O-GlcNAc; insulin resistance; type 2 diabetes; metabolic syndrome; adipocytokine; tandem mass spectrometry; shotgun proteomics; glycosylation; glycomics; N-linked; O-linked
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APA ·
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Manager
APA (6th Edition):
Lim, J. (2014). Secretome and glycome of mammalian adipocytes under insulin resistant conditions. (Thesis). University of Georgia. Retrieved from http://hdl.handle.net/10724/25543
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Lim, Jae-Min. “Secretome and glycome of mammalian adipocytes under insulin resistant conditions.” 2014. Thesis, University of Georgia. Accessed January 17, 2021.
http://hdl.handle.net/10724/25543.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Lim, Jae-Min. “Secretome and glycome of mammalian adipocytes under insulin resistant conditions.” 2014. Web. 17 Jan 2021.
Vancouver:
Lim J. Secretome and glycome of mammalian adipocytes under insulin resistant conditions. [Internet] [Thesis]. University of Georgia; 2014. [cited 2021 Jan 17].
Available from: http://hdl.handle.net/10724/25543.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Lim J. Secretome and glycome of mammalian adipocytes under insulin resistant conditions. [Thesis]. University of Georgia; 2014. Available from: http://hdl.handle.net/10724/25543
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Université Laval
26.
Gaudreau, Nathalie.
Stratégies de subsistance et identité culturelle des
occupants de Seal Islands (FaAw-5) au Labrador méridional entre
1760-1820.
Degree: 2011, Université Laval
URL: http://hdl.handle.net/20.500.11794/22588
► L'habitation semi-souterraine en tourbe retrouvée sur le site de Seal Islands (FaAw-5) à l'entrée du détroit de Belle Isle au Labrador méridional a été fouillée…
(more)
▼ L'habitation semi-souterraine en tourbe retrouvée
sur le site de Seal Islands (FaAw-5) à l'entrée du détroit de Belle
Isle au Labrador méridional a été fouillée et ensuite analysée dans
les années 1980. Cette étude a permis de proposer qu'elle avait été
occupée, entre 1760-1820, par un groupe inuit ayant subi une
intense acculturation. Les récentes analyses zooarchéologiques
réalisées à partir de l'assemblage faunique du site, dont l'analyse
cémentochronologique et l'étude comparative des marques de
boucherie sur les ossements de phoques, complétées par une analyse
des documents historiques et des données environnementales, ont
permis de proposer que les individus ayant occupé le site de Seal
Islands
n'étaient pas des Inuits, mais plutôt un groupe
d'Européens, du moins en partie. En effet, il est possible que le
site de Seal Islands soit un des premiers sites connus à révéler
des indices d'unions mixtes entre Européens et Inuits, ce qui nous
permettrait de mieux comprendre l'origine des Métis au Labrador.
Par ailleurs, plusieurs traits concernant les stratégies de
subsistance sur ce site ressemblent au mode de vie des Settlers qui
sont arrivés au Labrador en tant qu'employés pour les différents
établissements mercantiles. L'établissement de résidents permanents
européens représente une transition importante par rapport à
l'établissement temporaire et saisonnier de groupes de pêcheurs.
Ceux-ci ont dû s'adapter à un nouveau territoire et un nouveau
calendrier saisonnier afin d'acquérir des produits de subsistance,
de même que des biens avec une valeur commerciale.
Advisors/Committee Members: Bain, Allison, Woollett, James.
Subjects/Keywords: N 5333.1 UL 2011 G267; Fouilles (Archéologie) – Terre-Neuve-et-Labrador –
Seal, Île (53°14'N 55°42'O); Inuits – Terre-Neuve-et-Labrador – Seal, Île (53°14'N
55°42'O) – Mœurs et coutumes – 18e siècle; Inuits – Terre-Neuve-et-Labrador – Seal, Île (53°14'N
55°42'O) – Mœurs et coutumes – 19e siècle; Archéozoologie – Terre-Neuve-et-Labrador – Seal, Île
(53°14'N 55°42'O); Seal, Île (T.-N.-L. : 53°14'N 55°42'O)
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APA ·
Chicago ·
MLA ·
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CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Gaudreau, N. (2011). Stratégies de subsistance et identité culturelle des
occupants de Seal Islands (FaAw-5) au Labrador méridional entre
1760-1820. (Thesis). Université Laval. Retrieved from http://hdl.handle.net/20.500.11794/22588
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Gaudreau, Nathalie. “Stratégies de subsistance et identité culturelle des
occupants de Seal Islands (FaAw-5) au Labrador méridional entre
1760-1820.” 2011. Thesis, Université Laval. Accessed January 17, 2021.
http://hdl.handle.net/20.500.11794/22588.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Gaudreau, Nathalie. “Stratégies de subsistance et identité culturelle des
occupants de Seal Islands (FaAw-5) au Labrador méridional entre
1760-1820.” 2011. Web. 17 Jan 2021.
Vancouver:
Gaudreau N. Stratégies de subsistance et identité culturelle des
occupants de Seal Islands (FaAw-5) au Labrador méridional entre
1760-1820. [Internet] [Thesis]. Université Laval; 2011. [cited 2021 Jan 17].
Available from: http://hdl.handle.net/20.500.11794/22588.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Gaudreau N. Stratégies de subsistance et identité culturelle des
occupants de Seal Islands (FaAw-5) au Labrador méridional entre
1760-1820. [Thesis]. Université Laval; 2011. Available from: http://hdl.handle.net/20.500.11794/22588
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
27.
Silva, Fabiana Maria de Jesus.
Bem-estar subjectivo em crianças e adolescentes com síndrome de Turner : um estudo exploratório.
Degree: 2012, RCAAP
URL: https://www.rcaap.pt/detail.jsp?id=oai:repositorio.ulusiada.pt:11067/1670
► Dissertação de mestrado realizada no âmbito do Mestrado em Educação Especial.
Exame público realizado em 18 de Abril de 2013.
O estudo do Bem-Estar Subjetivo…
(more)
▼ Dissertação de mestrado realizada no âmbito do Mestrado em Educação Especial.
Exame público realizado em 18 de Abril de 2013.
O estudo do Bem-Estar Subjetivo (BES) como um construto amplo e multidimensional, revela-se de extrema importância para que se possa conhecer e perceber que mecanismos estão associados aos critérios de definição subjetivos de uma vida com qualidade, podendo, assim, potenciar-se níveis mais elevados de BES nos indivíduos. Poucas investigações se têm debruçado sobre o estudo do BES em crianças e adolescentes, não havendo investigações a este nível com população com Síndrome de Turner. O objectivo deste estudo exploratório foi avaliar o Bem-estar subjectivo numa perspectiva compósita em crianças e adolescentes com Síndrome de Turner. Participaram neste estudo 8 crianças e adolescentes (4 com ST e 4 crianças sem ST). Os participantes com Síndrome de Turner estavam a ser acompanhados por um serviço de um grande Hospital da Zona Noite de Portugal. Os diferentes componentes do BES foram avaliados, tendo em conta escalas de autorrelato: Escala Breve de Satisfação com a Vida, Escala Breve de Satisfação com o Suporte Social, Positive and Negative Affect Schedule (PANAS) e Escala breve de qualidade de vida associada à saúde mental (KIDSCREEN-lO). Os resultados revelaram que as crianças e adolescentes com e sem ST não se diferenciam, de forma significativa em termos estatístieos. Ao nível da estatística descritiva, este estudo exploratório identificou algumas tendências que deverão ser exploradas em futuros envolvendo um maior número de participantes. Apesar das tendências encontradas, estes resultados devem ser interpretados com cautela, já que o reduzido número de participantes não permite a generalização dos resultados.
The study of Subjective Well-Being (SWB) as a large and multidimensional construct, it associated to the extreme importance to know and understand what mechanisms are associated with subjective criteria for a life with quality, and what can increase higher levels in the individual SWB. Few investigations have been examining the SWB in children and adolescents with and without Turner Syndrome (TS). The purpose of this exploratory study was to evaluate the Subjective Well-Being according to a composite perspective in children and adolescents with Turner syndrome. Participants are 8 children and adolescents (4 with TS and 4 without TS). Participants with Turner syndrome were being followed by a service of a large hospital in the North Zone of Portugal. The different components of the SWB were evaluated, using selfreport scales: Brief Scale Satisfaction with Life, Scale of Satisfaction with Social Support, Positive and Negative Affect Schedule (PANAS) and Brief Scale of Quality of Life related to health mental (Kidscreen- 10). The results show that children and adolescents with and without TS did not differ significantly, in statistical terms. In tcrms of descriptive statistics, this exploratory study has identified some trends that should be explored in future involving a larger…
Advisors/Committee Members: Moreira, Paulo Alexandre Soares.
Subjects/Keywords: Educação Especial; Necessidades Educativas Especiais; Síndrome de Turner; Vida cognitiva; Teste Psicológico: Escala breve de satisfação com a vida (EBVS); Teste Psicológico: Escala breve de saúde mental (KIDSCREEN 10); Teste Psicológico: Positive and Negative Affect Schedule (PANAS); Teste Psicológico: Escala Breve de Satisfação com o Suporte Social (EBSSS)
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APA (6th Edition):
Silva, F. M. d. J. (2012). Bem-estar subjectivo em crianças e adolescentes com síndrome de Turner : um estudo exploratório. (Thesis). RCAAP. Retrieved from https://www.rcaap.pt/detail.jsp?id=oai:repositorio.ulusiada.pt:11067/1670
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Silva, Fabiana Maria de Jesus. “Bem-estar subjectivo em crianças e adolescentes com síndrome de Turner : um estudo exploratório.” 2012. Thesis, RCAAP. Accessed January 17, 2021.
https://www.rcaap.pt/detail.jsp?id=oai:repositorio.ulusiada.pt:11067/1670.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Silva, Fabiana Maria de Jesus. “Bem-estar subjectivo em crianças e adolescentes com síndrome de Turner : um estudo exploratório.” 2012. Web. 17 Jan 2021.
Vancouver:
Silva FMdJ. Bem-estar subjectivo em crianças e adolescentes com síndrome de Turner : um estudo exploratório. [Internet] [Thesis]. RCAAP; 2012. [cited 2021 Jan 17].
Available from: https://www.rcaap.pt/detail.jsp?id=oai:repositorio.ulusiada.pt:11067/1670.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Silva FMdJ. Bem-estar subjectivo em crianças e adolescentes com síndrome de Turner : um estudo exploratório. [Thesis]. RCAAP; 2012. Available from: https://www.rcaap.pt/detail.jsp?id=oai:repositorio.ulusiada.pt:11067/1670
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
28.
Touati, Bahria.
Développement de la réaction d’α-amidoalkylation catalytique directe des cétones catalysée par le super acide de Lewis Sn(NTf2)4 : Development of direct catalytic α-amidoalkylation of ketones catalyzed by super Lewis acid Sn(NTf2)4.
Degree: Docteur es, Chimie organique, 2014, Le Havre; Université de Carthage (Tunisie)
URL: http://www.theses.fr/2014LEHA0005
► La chimie des ions N-acyliminiums est un axe de recherche important dans le domaine de la chimie moderne. L’apport de la catalyse, avec l’utilisation de…
(more)
▼ La chimie des ions N-acyliminiums est un axe de recherche important dans le domaine de la chimie moderne. L’apport de la catalyse, avec l’utilisation de super acides de Lewis, a permis d’améliorer de nombreux processus synthétiques. Nous avons pu développer des réactions d’α-amidoalkylation catalytiques directes de cétones et d’aldéhydes. Ces réactions sont catalysées par des charges très faibles (0.5-2 mol%) du super acide de Lewis, le triflimidate d’étain IV Sn(NTf2)4 et donnent accès à une large gamme de structures carbonylées très intéressantes, avec de bons rendements. L’influence des différents paramètres gouvernant la réactivité et l’étendue de la méthode ont été étudiées. Par la suite, le potentiel synthétique des produits obtenus a été étudié. Deux stratégies de réactions intramoléculaires ont été testées à partir d’adduits alkylés judicieusement fonctionnalisés, en utilisant soit des catalyseurs à base d’or, soit des catalyseurs de métathèse, permettant d’atteindre quelques structures polycycliques.
AThe chemistry of N-acyliminiums ions is one important area of research in modern organic chemistry. Lewis superacid catalysis has contributed in the improvement of many synthetic processes. We have developed some direct α-amidoalkylation reactions starting from unmodified ketones and aldehydes. The reactions were catalyzed by the Lewis superacid tin IV triflimidate, Sn(NTf2)4, at a very low catalyst loading(0.5-2 mol%), providing access to a set of very interesting carbonylated structures in good yields. The influence of different parameters governing the reactivity and the scope of the reaction were studied. Thereafter, the synthetic potential of the obtained products was evaluated. Two intramolecular approaches from suitably functionalized alkylated products were tested using gold and metathesis catalysts, allowed access to some polycyclic structures.
Advisors/Committee Members: Dalla, Vincent (thesis director), Trabelsi-Ayadi, Malika (thesis director).
Subjects/Keywords: Super acidité de Lewis; Triflimidate d'étain; Métathèse ène-ène; Ions N-acyliminium; Catalyse à l'or; Α-amidoalkylation; N,O-actétals; 547
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APA ·
Chicago ·
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APA (6th Edition):
Touati, B. (2014). Développement de la réaction d’α-amidoalkylation catalytique directe des cétones catalysée par le super acide de Lewis Sn(NTf2)4 : Development of direct catalytic α-amidoalkylation of ketones catalyzed by super Lewis acid Sn(NTf2)4. (Doctoral Dissertation). Le Havre; Université de Carthage (Tunisie). Retrieved from http://www.theses.fr/2014LEHA0005
Chicago Manual of Style (16th Edition):
Touati, Bahria. “Développement de la réaction d’α-amidoalkylation catalytique directe des cétones catalysée par le super acide de Lewis Sn(NTf2)4 : Development of direct catalytic α-amidoalkylation of ketones catalyzed by super Lewis acid Sn(NTf2)4.” 2014. Doctoral Dissertation, Le Havre; Université de Carthage (Tunisie). Accessed January 17, 2021.
http://www.theses.fr/2014LEHA0005.
MLA Handbook (7th Edition):
Touati, Bahria. “Développement de la réaction d’α-amidoalkylation catalytique directe des cétones catalysée par le super acide de Lewis Sn(NTf2)4 : Development of direct catalytic α-amidoalkylation of ketones catalyzed by super Lewis acid Sn(NTf2)4.” 2014. Web. 17 Jan 2021.
Vancouver:
Touati B. Développement de la réaction d’α-amidoalkylation catalytique directe des cétones catalysée par le super acide de Lewis Sn(NTf2)4 : Development of direct catalytic α-amidoalkylation of ketones catalyzed by super Lewis acid Sn(NTf2)4. [Internet] [Doctoral dissertation]. Le Havre; Université de Carthage (Tunisie); 2014. [cited 2021 Jan 17].
Available from: http://www.theses.fr/2014LEHA0005.
Council of Science Editors:
Touati B. Développement de la réaction d’α-amidoalkylation catalytique directe des cétones catalysée par le super acide de Lewis Sn(NTf2)4 : Development of direct catalytic α-amidoalkylation of ketones catalyzed by super Lewis acid Sn(NTf2)4. [Doctoral Dissertation]. Le Havre; Université de Carthage (Tunisie); 2014. Available from: http://www.theses.fr/2014LEHA0005
29.
Sharma, Amit kumar.
Synthesis and Characterization of novel n o ndn s donor
ligands a transition metal complexes;.
Degree: Chemistry, 2008, Chaudhary Charan Singh University
URL: http://shodhganga.inflibnet.ac.in/handle/10603/25210
Subjects/Keywords: Novel N O; N S Donor Ligands; Metal Complexes
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APA ·
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APA (6th Edition):
Sharma, A. k. (2008). Synthesis and Characterization of novel n o ndn s donor
ligands a transition metal complexes;. (Thesis). Chaudhary Charan Singh University. Retrieved from http://shodhganga.inflibnet.ac.in/handle/10603/25210
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Sharma, Amit kumar. “Synthesis and Characterization of novel n o ndn s donor
ligands a transition metal complexes;.” 2008. Thesis, Chaudhary Charan Singh University. Accessed January 17, 2021.
http://shodhganga.inflibnet.ac.in/handle/10603/25210.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Sharma, Amit kumar. “Synthesis and Characterization of novel n o ndn s donor
ligands a transition metal complexes;.” 2008. Web. 17 Jan 2021.
Vancouver:
Sharma Ak. Synthesis and Characterization of novel n o ndn s donor
ligands a transition metal complexes;. [Internet] [Thesis]. Chaudhary Charan Singh University; 2008. [cited 2021 Jan 17].
Available from: http://shodhganga.inflibnet.ac.in/handle/10603/25210.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Sharma Ak. Synthesis and Characterization of novel n o ndn s donor
ligands a transition metal complexes;. [Thesis]. Chaudhary Charan Singh University; 2008. Available from: http://shodhganga.inflibnet.ac.in/handle/10603/25210
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Universidade de Brasília
30.
Priscila Gebrim Louly.
Uso do Tramadol no controle da tosse crônica : estudo N-DE-1 e revisão sistemática.
Degree: 2008, Universidade de Brasília
URL: http://bdtd.bce.unb.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=4620
► This work was developed from one Brazilian Hospitals case (Hospital Universitário de Brasília) in which the patient noticed a great improvement on her chronic cough…
(more)
▼ This work was developed from one Brazilian Hospitals case (Hospital Universitário de Brasília) in which the patient noticed a great improvement on her chronic cough (secondary to a interstitial pneumopathy) while using tramadol 50 mg 12/12h, an analgesic prescribed for pain. Hence, the patient has been using this medicine since then. Tramadol is a central-action opioid recommended to relieve moderate to severe pain that unexpectedly showed its positive effects in chronic cough control. However there are no previous reports in literature about its antitussive effects until now. This work used two methodologies: a N-of-1 randomized controlled trial to verify tramadol antitussive activity, and a systematic review of the tramadol and antitussive agents in order to investigate their efficacy in suppressing or relieving chronic cough. The N-of-1 trial showed that tramadol was effective in controlling the patients cough. This effectiveness has been evidenced by the significantly improvement (p <0.001) in the cough intensity (assessed by the patient in visual scale) and on her health state at all times when she was using the drug. The systematic review demonstrated that there are no clinical studies on the antitussive activity of tramadol. This work is the first systematic review aiming to evaluate the efficacy of antitussive agents. Seven drugs that reduced the cough frequency and intensity were identified: lidocaine, codeine, epinastine, terbutaline, levodropropizine, moguisteine and montelucast. It is still important to mention that the studies found faced some methodological problems, which we detach the diversity of the cough causes, lack of criteria for chronic cough definition, the variability of methods to quantify and analyze cough frequency and reduced follow up. Thus, further randomized and controlled clinical trials need to be conducted in order to demonstrate the efficacy of antitussive agents in the chronic cough control.
Este trabalho foi realizado a partir de um caso clínico em que uma paciente do Hospital Universitário de Brasília observou melhora da tosse crônica, secundária a uma pneumopatia intersticial, com o uso de tramadol 50 mg 12/12h, que havia sido prescrito para a dor. Esse fato fez com que a paciente utilizasse o tramadol continuamente. Não foram encontrados na literatura estudos clínicos que evidenciassem a atividade antitussígena do tramadol, um analgésico opióide. O presente trabalho utilizou duas metodologias: um teste N-de-1 randomizado, duplo-cego e placebo controlado para validar a ação antitussígena do tramadol; e uma revisão sistemática para investigar a evidência científica disponível do tramadol e dos antitussígenos no controle da tosse crônica. O teste N-de-1 mostrou que o tramadol foi efetivo em reduzir a tosse da paciente. Esse efeito foi evidenciado pela redução significativa (p<0,001) na intensidade da tosse diurna e noturna avaliada por uma escala visual (de 0 a 5) no período em que utilizou o medicamento comparado ao placebo. Além disso, a paciente observou uma melhora…
Advisors/Committee Members: Patricia Medeiros de Souza, Carlos Eduardo Ventura Gaio dos Santos, Leopoldo Luiz Santos Neto, Marcelo Palmeira Rodrigues, Mauricio Pereira Gomes.
Subjects/Keywords: antitussígenos; revisão sistemática; MEDICINA; chronic cough; tramadol; N-of-1 trial; tosse crônica; tramadol; systematic review; teste N-DE-1; antitussive agents
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Record Details
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Louly, P. G. (2008). Uso do Tramadol no controle da tosse crônica : estudo N-DE-1 e revisão sistemática. (Thesis). Universidade de Brasília. Retrieved from http://bdtd.bce.unb.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=4620
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Louly, Priscila Gebrim. “Uso do Tramadol no controle da tosse crônica : estudo N-DE-1 e revisão sistemática.” 2008. Thesis, Universidade de Brasília. Accessed January 17, 2021.
http://bdtd.bce.unb.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=4620.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Louly, Priscila Gebrim. “Uso do Tramadol no controle da tosse crônica : estudo N-DE-1 e revisão sistemática.” 2008. Web. 17 Jan 2021.
Vancouver:
Louly PG. Uso do Tramadol no controle da tosse crônica : estudo N-DE-1 e revisão sistemática. [Internet] [Thesis]. Universidade de Brasília; 2008. [cited 2021 Jan 17].
Available from: http://bdtd.bce.unb.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=4620.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Louly PG. Uso do Tramadol no controle da tosse crônica : estudo N-DE-1 e revisão sistemática. [Thesis]. Universidade de Brasília; 2008. Available from: http://bdtd.bce.unb.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=4620
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
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Open Access Theses and Dissertations