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Brigham Young University

1. Strong, Austin Michael. Lean Six Sigma's Impact on Firm Innovation Performance.

Degree: MS, 2018, Brigham Young University

Following Toyota's dramatic rise to prominence within the automotive industry in the late 1980's, firms around the globe have widely sought to adopt Lean Six Sigma (LSS) as a means of reducing costs, improving quality, and gaining an overall competitive advantage. While the operational benefits of LSS are largely undisputed, there are criticisms of the movement with regards to its effect on firm innovation capability. Prior academic studies investigating the relationship between LSS and innovation are largely conceptual in nature, rely heavily on qualitative data, and display a high degree of variability in results. The objective of this work was to empirically confirm whether LSS adoption had a positive, negative, or neutral impact on firm innovation performance.Financial data was collected for 151 publicly traded firms over the period from 1985 to 2018. The year of company-wide adoption of LSS was identified for each sample firm. Firms were paired with industry rivals using Coarsened Exact Matching (CEM), and statistical regressions were performed to show correlations between LSS implementation (as measured by inventory turns) and innovation performance (as measured by Total Factor Productivity, Research Quotient, and Tobin's Quotient). Regression results indicated that LSS implementation had a positive correlation with firm process innovation performance and the overall market perception of firm innovation and value, and a negative-to-neutral correlation with firm product innovation performance. Additional regressions performed at the industry-sector level revealed that the LSS-innovation relationship varies greatly by industry environment and is subject to unique industry effects and management implementation decisions.

Subjects/Keywords: lean manufacturing; six sigma; lean six sigma; LSS; innovation; product innovation; process innovation; Tobin's quotient; TQ; total factor productivity; TFP; research quotient; RQ; Austin Michael Strong; Science and Technology Studies

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Strong, A. M. (2018). Lean Six Sigma's Impact on Firm Innovation Performance. (Masters Thesis). Brigham Young University. Retrieved from https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=7877&context=etd

Chicago Manual of Style (16th Edition):

Strong, Austin Michael. “Lean Six Sigma's Impact on Firm Innovation Performance.” 2018. Masters Thesis, Brigham Young University. Accessed April 17, 2021. https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=7877&context=etd.

MLA Handbook (7th Edition):

Strong, Austin Michael. “Lean Six Sigma's Impact on Firm Innovation Performance.” 2018. Web. 17 Apr 2021.

Vancouver:

Strong AM. Lean Six Sigma's Impact on Firm Innovation Performance. [Internet] [Masters thesis]. Brigham Young University; 2018. [cited 2021 Apr 17]. Available from: https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=7877&context=etd.

Council of Science Editors:

Strong AM. Lean Six Sigma's Impact on Firm Innovation Performance. [Masters Thesis]. Brigham Young University; 2018. Available from: https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=7877&context=etd


Georgia Tech

2. Roberts, Lezah Wilette. Effect of Netropsin on One-electron Oxidation of DNA.

Degree: PhD, Chemistry and Biochemistry, 2005, Georgia Tech

One electron oxidation of DNA has been studied extensively over the years. When a charge is injected into a DNA duplex, it migrates through the DNA until it reaches a trap. Upon further reactions, damage occurs in this area and strand cleavage can occur. Many works have been performed to see what can affect this damage to DNA. Netropsin is a minor groove binder that can bind to tracts of four to five A:T base pairs. It has been used in the studies within to determine if it can protect DNA against oxidative damage, caused by one-electron oxidation, when it is bound within the minor groove of the DNA. By using a naphthacenedione derivative as a photosensitizer, several DNA duplexes containing netropsin binding sites as well as those without binding sites, were irradiated at 420 nm, analyzed, and visualized to determine its effect on oxidative damage. It has been determined netropsin creates a quenching sphere of an average of 5.8 * 108 Ć whether bound to the DNA or not. Herein we will show netropsin protects DNA against oxidative damage whether it is free in solutions or bound within the minor groove of a DNA duplex. Advisors/Committee Members: Gary B. Schuster (Committee Chair), Donald Doyle (Committee Member), Laren Tolbert (Committee Member), Nicholas V. Hud (Committee Member), Roger Wartell (Committee Member).

Subjects/Keywords: Photosensitizer; Charge transfer; Netropsin; TQ; DNA; Electron transfer; One-electron oxidation; Photosensitization, Biological; Charge transfer in biology; DNA Analysis; Oxidation, Physiological

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Roberts, L. W. (2005). Effect of Netropsin on One-electron Oxidation of DNA. (Doctoral Dissertation). Georgia Tech. Retrieved from http://hdl.handle.net/1853/7228

Chicago Manual of Style (16th Edition):

Roberts, Lezah Wilette. “Effect of Netropsin on One-electron Oxidation of DNA.” 2005. Doctoral Dissertation, Georgia Tech. Accessed April 17, 2021. http://hdl.handle.net/1853/7228.

MLA Handbook (7th Edition):

Roberts, Lezah Wilette. “Effect of Netropsin on One-electron Oxidation of DNA.” 2005. Web. 17 Apr 2021.

Vancouver:

Roberts LW. Effect of Netropsin on One-electron Oxidation of DNA. [Internet] [Doctoral dissertation]. Georgia Tech; 2005. [cited 2021 Apr 17]. Available from: http://hdl.handle.net/1853/7228.

Council of Science Editors:

Roberts LW. Effect of Netropsin on One-electron Oxidation of DNA. [Doctoral Dissertation]. Georgia Tech; 2005. Available from: http://hdl.handle.net/1853/7228

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