subject:(Suzuki reaction)

University of Saskatchewan

1. Li, Hanxiang 1989-. The versatility of palladium systems: from palladacycles to cyclic peptides and beyond.

Degree: 2015, University of Saskatchewan

► This work started with the aim to synthesize monomeric ring-opened analogues of the palladacycles [(iminoisoidoline)PdCl(PCy3)] incorporating iminoisoindoline and phosphine ligands, and evaluate their catalytic activities… (more)

Subjects/Keywords: palladacycle; cyclic peptide; suzuki reaction

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APA (6^th Edition):

Li, H. 1. (2015). The versatility of palladium systems: from palladacycles to cyclic peptides and beyond. (Thesis). University of Saskatchewan. Retrieved from http://hdl.handle.net/10388/12420

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Li, Hanxiang 1989-. “The versatility of palladium systems: from palladacycles to cyclic peptides and beyond.” 2015. Thesis, University of Saskatchewan. Accessed March 07, 2021. http://hdl.handle.net/10388/12420.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Li, Hanxiang 1989-. “The versatility of palladium systems: from palladacycles to cyclic peptides and beyond.” 2015. Web. 07 Mar 2021.

Vancouver:

Li H1. The versatility of palladium systems: from palladacycles to cyclic peptides and beyond. [Internet] [Thesis]. University of Saskatchewan; 2015. [cited 2021 Mar 07]. Available from: http://hdl.handle.net/10388/12420.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Li H1. The versatility of palladium systems: from palladacycles to cyclic peptides and beyond. [Thesis]. University of Saskatchewan; 2015. Available from: http://hdl.handle.net/10388/12420

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Johannes Gutenberg Universität Mainz

2. Breuch, Denis. Kontinuierliche Kreuzkupplungsreaktionen in mikrostrukturierten Systemen.

Degree: 2013, Johannes Gutenberg Universität Mainz

URL: http://ubm.opus.hbz-nrw.de/volltexte/2013/3443/

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Im Rahmen dieser Arbeit wurden unterschiedliche Palladium-katalysierte Kreuzkupplungsreaktionen untersucht. Ein besonderes Augenmerk wurde dabei auf die Suzuki-Miyaura-Reaktion gelegt. Unter anderem aufgrund der langen Reaktionszeiten und… (more)

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Im Rahmen dieser Arbeit wurden unterschiedliche Palladium-katalysierte Kreuzkupplungsreaktionen untersucht. Ein besonderes Augenmerk wurde dabei auf die Suzuki-Miyaura-Reaktion gelegt. Unter anderem aufgrund der langen Reaktionszeiten und der zweiphasigen Bedingungen ist diese Reaktionsklasse nur sehr schwer als kontinuierlicher Prozess zu etablieren. Vielen dieser Ansätze ist jedoch zu eigen, dass der große Vorteil der Mikroprozesstechnik, eine überlegene Kontrolle von Temperatur und Stofftransport, kaum ausgeschöpft wird. An diesem Punkt setzt diese Arbeit von technischer aus Seite an. Der zweite Schwerpunkt der Arbeit sind die prinzipiellen Untersuchungen an kontinuierlichen Flüssig-Flüssig-Zwei-Phasen-Reaktionen. Im Zuge des DBU-finanzierten Transkat-Projektes wurden hierbei anhand einfacher Veresterungsreaktionen grundlegende Kenntnisse zu Stofftransport, Grenzflächen und Phasentrennung innerhalb mikrostrukturierter Systeme gesammelt. Dank speziell angefertigter Glasmikroreaktoren von der Firma mikroglas chemtech GmbH war eine genaue optische und digitale Charakterisierung der Phasengrenzflächen möglich. Ein wichtiges Ergebnis war darüber hinaus, dass ionische Flüssigkeiten, als eigenständige Phasen verwendet, enorm zum Massentransfer und somit zur Reaktionsgeschwindigkeit beitragen können.

In this study, different palladium-catalyzed cross-coupling reactions were examined. Special attention was paid to the Suzuki-Miyaura reaction. The long reaction times and the biphasic reaction conditions make it difficult to optimize a continuous flow synthesis. Many of the previously described approaches, however, do not use the advantages of micro process technology, i.e. superior control of temperature and mass transfer. The aim of this study was to optimize these parameters. Special emphasis was also placed on the general optimization of continuous liquid-liquid two-phase reactions. In the course of the DBU-funded project Transkat, more information about mass transports, interfacial areas and phase separations in microstructured systems was collected via simple esterification reactions. Because of custom-made glass microreactors of the mikroglas chemtech GmbH, a precise optical and digital characterization of the interfacial areas was possible. Another important result was that ionic liquids, if used as an separate phases, can fuel an enormous mass transfer and thus increase the reaction rate.

Subjects/Keywords: Mikroreaktor; Suzuki-Reaktion; ionische Flüssigkeit; micro reactor; Suzuki reaction; ionic liquid; Chemistry and allied sciences

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APA (6^th Edition):

Breuch, D. (2013). Kontinuierliche Kreuzkupplungsreaktionen in mikrostrukturierten Systemen. (Doctoral Dissertation). Johannes Gutenberg Universität Mainz. Retrieved from http://ubm.opus.hbz-nrw.de/volltexte/2013/3443/

Chicago Manual of Style (16^th Edition):

Breuch, Denis. “Kontinuierliche Kreuzkupplungsreaktionen in mikrostrukturierten Systemen.” 2013. Doctoral Dissertation, Johannes Gutenberg Universität Mainz. Accessed March 07, 2021. http://ubm.opus.hbz-nrw.de/volltexte/2013/3443/.

MLA Handbook (7^th Edition):

Breuch, Denis. “Kontinuierliche Kreuzkupplungsreaktionen in mikrostrukturierten Systemen.” 2013. Web. 07 Mar 2021.

Vancouver:

Breuch D. Kontinuierliche Kreuzkupplungsreaktionen in mikrostrukturierten Systemen. [Internet] [Doctoral dissertation]. Johannes Gutenberg Universität Mainz; 2013. [cited 2021 Mar 07]. Available from: http://ubm.opus.hbz-nrw.de/volltexte/2013/3443/.

Council of Science Editors:

Breuch D. Kontinuierliche Kreuzkupplungsreaktionen in mikrostrukturierten Systemen. [Doctoral Dissertation]. Johannes Gutenberg Universität Mainz; 2013. Available from: http://ubm.opus.hbz-nrw.de/volltexte/2013/3443/

3. Takimoto, Herick Garcia. Estudo de polifluorenos como camada emissora de dispositivos eletroluminescentes eficientes.

Degree: Mestrado, Engenharia Metalúrgica e de Materiais, 2013, University of São Paulo

URL: http://www.teses.usp.br/teses/disponiveis/3/3133/tde-23052014-014442/ ;

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Este trabalho tem como principais objetivos: desenvolver procedimentos sintéticos e novos materiais poliméricos que apresentem boa condutividade elétrica, estudar o comportamento eletro-óptico dos polímeros obtidos,… (more)

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Este trabalho tem como principais objetivos: desenvolver procedimentos sintéticos e novos materiais poliméricos que apresentem boa condutividade elétrica, estudar o comportamento eletro-óptico dos polímeros obtidos, desenvolver procedimentos para a construção de dispositivos eletroluminescentes, caracterizá-los e correlacionar as características eletro-ópticas observadas com a constituição da camada ativa polimérica. Foram realizadas diversas sínteses objetivando a preparação de polifluorenos com diferentes estruturas químicas a partir de monômeros difuncionais aromáticos boronados e bromados, utilizando uma mesma rota de acoplamento de Suzuki. Assim, foram preparados três polímeros, poli[2,7-(9,9-dioctilfluoreno)] (PF, polifluoreno), poli[1,4-fenileno-alt-2,7- (9,9-dioctilfluoreno)] [PFP, poli(fluoreno-fenileno)] e poli[(1,4-fenileno-2-flúor)-alt-2,7-(9,9- dioctilfluoreno)] [PFPF, poli(fluoreno-fenileno)fluorado]. Para obtenção destes polifluorenos com bom rendimento e com pureza adequada para a preparação de dispositivos poliméricos eletroluminescentes, foi necessário testar diversas condições de reação, até a otimização de um procedimento sintético robusto. Os polifluorenos preparados foram exaustivamente purificados por extração e solubilização-precipitação. Todos os polifluorenos tiveram a sua estrutura e composição químicas caracterizadas e confirmadas pelas técnicas de espectroscopia no infravermelho (FTIR), espectroscopia de ressonância magnética nuclear de hidrogênio (¹HNMR) e espectroscopia de energia dispersiva de raios-X (EDX). As massas molares médias e a polidispersão foram determinadas por cromatografia de permeação em gel (GPC). Soluções em clorofórmio dos polifluorenos foram analisadas por espectroscopias de absorção e emissão no UV-Vis. Estes resultados nos forneceram informações importantes quanto às propriedades de fotoluminescência dos polifluorenos obtidos. Até o momento, sabe-se que todos os três polímeros emitem cor azul e dentre as três estruturas estudadas, o PFPF apresentou maior intensidade de fluorescência. Para a fabricação dos P-OLEDs (Diodos Orgânico-Polimérico Emissor de Luz) foram feitas soluções de clorofórmio em concentrações de 1% dos três tipos de polímeros. Também foi estudada a influência dos compostos ETL (electron transport layer) (Alq3 ou butyl-PBD) com concentrações de 0,5%. Quando aplicada uma tensão no dispositivo, o PFPF apresentou menor tensão de operação entre os polímeros estudados. A partir das curvas de tensão vs. corrente, verificou-se que a adição do butyl-PBD nos três tipos de polímeros diminui a tensão de limiar em comparação com os dispositivos sem composto ETL. Os comprimentos de onda de eletroluminescência dos dispositivos polarizados permaneceram constante mesmo com a adição dos dois compostos ETL (Alq3 ou butyl-PBD).

This work has as main objectives: develop synthetic procedures and new electroluminescent polymeric materials that have good electrical conductivity, study the behavior of polymer systems thus obtained, and develop procedures for the…

Advisors/Committee Members: Wang, Shu Hui.

Subjects/Keywords: ITO; ITO; P-OLEDs; P-OLEDs; Polifluoreno; Polyfluorene; Reação Suzuki; Suzuki reaction

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APA (6^th Edition):

Takimoto, H. G. (2013). Estudo de polifluorenos como camada emissora de dispositivos eletroluminescentes eficientes. (Masters Thesis). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/3/3133/tde-23052014-014442/ ;

Chicago Manual of Style (16^th Edition):

Takimoto, Herick Garcia. “Estudo de polifluorenos como camada emissora de dispositivos eletroluminescentes eficientes.” 2013. Masters Thesis, University of São Paulo. Accessed March 07, 2021. http://www.teses.usp.br/teses/disponiveis/3/3133/tde-23052014-014442/ ;.

MLA Handbook (7^th Edition):

Takimoto, Herick Garcia. “Estudo de polifluorenos como camada emissora de dispositivos eletroluminescentes eficientes.” 2013. Web. 07 Mar 2021.

Vancouver:

Takimoto HG. Estudo de polifluorenos como camada emissora de dispositivos eletroluminescentes eficientes. [Internet] [Masters thesis]. University of São Paulo; 2013. [cited 2021 Mar 07]. Available from: http://www.teses.usp.br/teses/disponiveis/3/3133/tde-23052014-014442/ ;.

Council of Science Editors:

Takimoto HG. Estudo de polifluorenos como camada emissora de dispositivos eletroluminescentes eficientes. [Masters Thesis]. University of São Paulo; 2013. Available from: http://www.teses.usp.br/teses/disponiveis/3/3133/tde-23052014-014442/ ;

University of KwaZulu-Natal

4. Molefe, Patience Snenhlanhla Sthembile. Base-Free Suzuki acylation reactions of sodium (aryl trihydroxyborate) salts: a novel synthesis of substituted aryl ketones.

Degree: 2018, University of KwaZulu-Natal

URL: https://researchspace.ukzn.ac.za/handle/10413/18146

► Asymmetric biaryl ketones are important building block in organic chemistry since they occur in large number of biological active compounds, natural product, cosmetics as well… (more)

▼ Asymmetric biaryl ketones are important building block in organic chemistry since they occur in large number of biological active compounds, natural product, cosmetics as well as in organic synthesis. The aim of this project was to develop a novel base-free Suzuki-Miyaura cross-coupling of biaryl ketones from sodium (aryl trihydroxyborate) salts coupled with acyl chlorides catalysed by palladium precursor and investigate the electron effect of substituents attached to acyl chloride and sodium (aryl trihydroxyborate) salts on the yields of ketones produced. A novel synthesis of biaryl ketones was successfully developed in coupling of commercially available substituted acyl chlorides with easily accessible substituted sodium (aryl trihydroxyborate) salts catalysed by Pd(PPh3)4 in aqueous toluene. A wide range of functional groups were accommodated including CF3, OMe, SMe, Br, F, NO2, OH, NH2 yielding up to 96% in 24 hours. Encouraged by successful cross-coupling reaction between sodium (aryl trihydroxyborate) salts and acyl chlorides under the Suzuki-Miyaura cross-coupling acylation reaction conditions, we thought it would be logical to extend the scope of the developed reaction condition to include carboxylic anhydrides as electrophiles. As a result, substituted benzoic anhydrides were first synthesised following previously published procedures giving the desired products in excellent yields (87-99%). The synthesised carboxylic anhydrides were subsequently cross-coupled with boronate salts under base-free and ligandless palladium catalysed cross-coupling reaction conditions to synthesise biaryl ketones in aqueous acetone. The developed method appears sensitive to electronic effects both on the electrophile and on the nucleophile and on the nucleophile furnishing the desired ketones in moderate yields. Two novel methods have been developed to synthesise ketones from stable, easy to prepare and free flowing pure sodium (aryl trihydroxyborate) salts. Advisors/Committee Members: Sithebe, Siphamandla. (advisor).

Subjects/Keywords: Base-free Suzuki.; Sodium salts.; Aryl trihydroxyborate.; Ketones.; Suzuki-Miyaura cross-coupling acylation reaction.

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APA (6^th Edition):

Molefe, P. S. S. (2018). Base-Free Suzuki acylation reactions of sodium (aryl trihydroxyborate) salts: a novel synthesis of substituted aryl ketones. (Thesis). University of KwaZulu-Natal. Retrieved from https://researchspace.ukzn.ac.za/handle/10413/18146

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Molefe, Patience Snenhlanhla Sthembile. “Base-Free Suzuki acylation reactions of sodium (aryl trihydroxyborate) salts: a novel synthesis of substituted aryl ketones.” 2018. Thesis, University of KwaZulu-Natal. Accessed March 07, 2021. https://researchspace.ukzn.ac.za/handle/10413/18146.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Molefe, Patience Snenhlanhla Sthembile. “Base-Free Suzuki acylation reactions of sodium (aryl trihydroxyborate) salts: a novel synthesis of substituted aryl ketones.” 2018. Web. 07 Mar 2021.

Vancouver:

Molefe PSS. Base-Free Suzuki acylation reactions of sodium (aryl trihydroxyborate) salts: a novel synthesis of substituted aryl ketones. [Internet] [Thesis]. University of KwaZulu-Natal; 2018. [cited 2021 Mar 07]. Available from: https://researchspace.ukzn.ac.za/handle/10413/18146.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Molefe PSS. Base-Free Suzuki acylation reactions of sodium (aryl trihydroxyborate) salts: a novel synthesis of substituted aryl ketones. [Thesis]. University of KwaZulu-Natal; 2018. Available from: https://researchspace.ukzn.ac.za/handle/10413/18146

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Virginia Commonwealth University

5. Martin, Alex D. A Convergent Approach to the Continuous Synthesis of Telmisartan via a Suzuki Reaction between Two Functionalized Benzimidazoles.

Degree: PhD, Chemistry, 2015, Virginia Commonwealth University

URL: https://doi.org/10.25772/2TDP-NQ30 ; https://scholarscompass.vcu.edu/etd/3750

► A direct and highly efficient synthesis has been developed for telmisartan, the active ingredient in the widely prescribed antihypertensive drug Micardis®. This approach brings… (more)

Subjects/Keywords: telmisartan; suzuki reaction; flow chemistry; API synthesis; antihypertensive; Organic Chemistry

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APA (6^th Edition):

Martin, A. D. (2015). A Convergent Approach to the Continuous Synthesis of Telmisartan via a Suzuki Reaction between Two Functionalized Benzimidazoles. (Doctoral Dissertation). Virginia Commonwealth University. Retrieved from https://doi.org/10.25772/2TDP-NQ30 ; https://scholarscompass.vcu.edu/etd/3750

Chicago Manual of Style (16^th Edition):

Martin, Alex D. “A Convergent Approach to the Continuous Synthesis of Telmisartan via a Suzuki Reaction between Two Functionalized Benzimidazoles.” 2015. Doctoral Dissertation, Virginia Commonwealth University. Accessed March 07, 2021. https://doi.org/10.25772/2TDP-NQ30 ; https://scholarscompass.vcu.edu/etd/3750.

MLA Handbook (7^th Edition):

Martin, Alex D. “A Convergent Approach to the Continuous Synthesis of Telmisartan via a Suzuki Reaction between Two Functionalized Benzimidazoles.” 2015. Web. 07 Mar 2021.

Vancouver:

Martin AD. A Convergent Approach to the Continuous Synthesis of Telmisartan via a Suzuki Reaction between Two Functionalized Benzimidazoles. [Internet] [Doctoral dissertation]. Virginia Commonwealth University; 2015. [cited 2021 Mar 07]. Available from: https://doi.org/10.25772/2TDP-NQ30 ; https://scholarscompass.vcu.edu/etd/3750.

Council of Science Editors:

Martin AD. A Convergent Approach to the Continuous Synthesis of Telmisartan via a Suzuki Reaction between Two Functionalized Benzimidazoles. [Doctoral Dissertation]. Virginia Commonwealth University; 2015. Available from: https://doi.org/10.25772/2TDP-NQ30 ; https://scholarscompass.vcu.edu/etd/3750

Boston College

6. Eliseeva, Maria N. New Route to a [5,5] Carbon Nanotube End-Cap via Direct Borylation of Corannulene.

Degree: MS, Chemistry, 2011, Boston College

URL: http://dlib.bc.edu/islandora/object/bc-ir:101796

► The Scott lab is interested in the functionalization of corannulene as a building block for large polycyclic aromatic hydrocarbons and carbon nanotube end-cap precursors. Toward… (more)

Subjects/Keywords: carbon nanotube; corannulene; direct borylation; iridium catalyst; Suzuki reaction

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APA (6^th Edition):

Eliseeva, M. N. (2011). New Route to a [5,5] Carbon Nanotube End-Cap via Direct Borylation of Corannulene. (Masters Thesis). Boston College. Retrieved from http://dlib.bc.edu/islandora/object/bc-ir:101796

Chicago Manual of Style (16^th Edition):

Eliseeva, Maria N. “New Route to a [5,5] Carbon Nanotube End-Cap via Direct Borylation of Corannulene.” 2011. Masters Thesis, Boston College. Accessed March 07, 2021. http://dlib.bc.edu/islandora/object/bc-ir:101796.

MLA Handbook (7^th Edition):

Eliseeva, Maria N. “New Route to a [5,5] Carbon Nanotube End-Cap via Direct Borylation of Corannulene.” 2011. Web. 07 Mar 2021.

Vancouver:

Eliseeva MN. New Route to a [5,5] Carbon Nanotube End-Cap via Direct Borylation of Corannulene. [Internet] [Masters thesis]. Boston College; 2011. [cited 2021 Mar 07]. Available from: http://dlib.bc.edu/islandora/object/bc-ir:101796.

Council of Science Editors:

Eliseeva MN. New Route to a [5,5] Carbon Nanotube End-Cap via Direct Borylation of Corannulene. [Masters Thesis]. Boston College; 2011. Available from: http://dlib.bc.edu/islandora/object/bc-ir:101796

University of South Carolina

7. Key, Ryan J. Development of Nickel Catalyzed Cross-Coupling Methodologies.

Degree: PhD, Chemistry and Biochemistry, 2019, University of South Carolina

URL: https://scholarcommons.sc.edu/etd/5324

► In this work, we have addressed some of the issues surrounding catalytic crosscoupling reactions by using a nickel terpyridine catalyst, [Ni(tpy)(py)(CH3CN)2](PF6)2 in the Buchwald-Hartwig… (more)

Subjects/Keywords: Chemistry; nickel; cross-coupling; Atomic Layer Deposition; Suzuki reaction

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Key, R. J. (2019). Development of Nickel Catalyzed Cross-Coupling Methodologies. (Doctoral Dissertation). University of South Carolina. Retrieved from https://scholarcommons.sc.edu/etd/5324

Chicago Manual of Style (16^th Edition):

Key, Ryan J. “Development of Nickel Catalyzed Cross-Coupling Methodologies.” 2019. Doctoral Dissertation, University of South Carolina. Accessed March 07, 2021. https://scholarcommons.sc.edu/etd/5324.

MLA Handbook (7^th Edition):

Key, Ryan J. “Development of Nickel Catalyzed Cross-Coupling Methodologies.” 2019. Web. 07 Mar 2021.

Vancouver:

Key RJ. Development of Nickel Catalyzed Cross-Coupling Methodologies. [Internet] [Doctoral dissertation]. University of South Carolina; 2019. [cited 2021 Mar 07]. Available from: https://scholarcommons.sc.edu/etd/5324.

Council of Science Editors:

Key RJ. Development of Nickel Catalyzed Cross-Coupling Methodologies. [Doctoral Dissertation]. University of South Carolina; 2019. Available from: https://scholarcommons.sc.edu/etd/5324

8. Geogheghan, Katherine Jayne. Boronic acid speciation in Suzuki-Miyaura cross-coupling.

Degree: PhD, 2018, University of Edinburgh

URL: http://hdl.handle.net/1842/33092

► Since its discovery in 1979, the Suzuki-Miyaura (SM) reaction has become one of the most widely utilised tools for carbon-carbon bond formation. The palladium catalysed… (more)

▼ Since its discovery in 1979, the Suzuki-Miyaura (SM) reaction has become one of the most widely utilised tools for carbon-carbon bond formation. The palladium catalysed coupling of an organoboron and organohalide compounds proceeds through a three-stage mechanism of oxidative addition, transmetalation and reductive elimination. The transmetalation of boronic acids to a palladium(II) complex has been widely studied. However, very little is known about the transmetalation of boronic esters, which are commonly used as an alternative to unstable boronic acids. Whether these species undergo direct transmetalation or prior hydrolysis to the boronic acid under SM conditions remains unknown. This research aimed to elucidate the mechanism of this cross-coupling process. Initial results under typical SM conditions created a biphasic reaction, promoted by the inorganic base and solvent composition, and showed that the boronic esters and corresponding boronic acid couple at the same absolute rate. This is thought to be a consequence of the formation of a biphasic mixture, rendering phase transfer the turnover-limiting step. The conditions were thus adapted to maintain a monophasic system using an organic soluble base, 2-tert-butyl-1,1,3,3-tetramethylguanidine, enabling the focus to be transmetalation as the turnover-limiting step. These new conditions show a significant difference in both reaction rate and induction period when using a boronic ester compared to the corresponding boronic acid. The use of guanidine was also shown to have an interesting effect on the boronic acid/ester species by 19F and 11B NMR. Further studies found the use of guanidine to create a boronate species, with this species being an aryl trihydroxyboronate or the hydroxyl"ate"-complex of the boronic ester, depending on the presence of diol in the system. Formation of a boronate species was found to be crucial for efficient cross-coupling. When testing weaker bases, unable to form a boronate species, poor SM cross-coupling conversion was found using the newly developed phosphine-free guanidine conditions, showing the importance of the boronate species under these conditions. The results suggest that depending on the strength of base used, the pathway of transmetalation pathway can be switched, between the boronate pathway and the oxo-palladium pathway, under the specific conditions developed.

Subjects/Keywords: 660; cross-coupling; Suzuki-Miyaura reaction; palladium catalysed coupling; boronic esters

6 more images…

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APA (6^th Edition):

Geogheghan, K. J. (2018). Boronic acid speciation in Suzuki-Miyaura cross-coupling. (Doctoral Dissertation). University of Edinburgh. Retrieved from http://hdl.handle.net/1842/33092

Chicago Manual of Style (16^th Edition):

Geogheghan, Katherine Jayne. “Boronic acid speciation in Suzuki-Miyaura cross-coupling.” 2018. Doctoral Dissertation, University of Edinburgh. Accessed March 07, 2021. http://hdl.handle.net/1842/33092.

MLA Handbook (7^th Edition):

Geogheghan, Katherine Jayne. “Boronic acid speciation in Suzuki-Miyaura cross-coupling.” 2018. Web. 07 Mar 2021.

Vancouver:

Geogheghan KJ. Boronic acid speciation in Suzuki-Miyaura cross-coupling. [Internet] [Doctoral dissertation]. University of Edinburgh; 2018. [cited 2021 Mar 07]. Available from: http://hdl.handle.net/1842/33092.

Council of Science Editors:

Geogheghan KJ. Boronic acid speciation in Suzuki-Miyaura cross-coupling. [Doctoral Dissertation]. University of Edinburgh; 2018. Available from: http://hdl.handle.net/1842/33092

Universidade Federal de Viçosa

9. Guilherme Carvalho Geraldo. Síntese e avaliação da atividade fitotóxica de análogos ao alternariol.

Degree: 2008, Universidade Federal de Viçosa

URL: http://www.tede.ufv.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=1891

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O alternariol é uma lactona aromática produzida por espécies fúngicas fitopatogênicas dos gêneros Nimbya e Alternaria. Estas espécies são conhecidas por causarem necroses foliares ocasionando… (more)

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O alternariol é uma lactona aromática produzida por espécies fúngicas fitopatogênicas dos gêneros Nimbya e Alternaria. Estas espécies são conhecidas por causarem necroses foliares ocasionando a morte da planta, inclusive de espécies de plantas daninhas como Alternathera philoxeroides. Acredita-se que parte da fitotoxicidade destes fungos esteja associada à produção deste composto, podendo estar presentes também outros metabólitos secundários. O presente trabalho teve por objetivos sintetizar análogos ao alternariol e avaliar a atividade fitotóxica dos mesmos. Para a síntese destes foram utilizados dois tipos de aldeídos aromáticos (2-bromo-4,6- dimetoxibenzaldeído, obtido por formilação de Vilsmeyer, e 2- bromobenzaldeído) que foram acoplados com diversos ácidos borônicos através da reação de acoplamento de Suzuki. As biarilas resultantes foram oxidadas com clorito de sódio (NaClO2) para obtenção dos ácidos carboxílicos correspondentes, que foram tratados com tribrometo de boro (BBr3) para a desproteção dos grupos hidroxilas com conseqüente ciclização e formação do anel lactônico dos análogos ao alternariol. Desta forma foram obtidos oito novos compostos: 7,9-diidroxi-2-metil-6Hbenzo[c]cromen-6-ona (34,5%), 2-cloro-7,9-diidroxi-6H-benzo[c]cromen-6-ona (55,0%), 3-fluoro-7,9-diidroxi-6H-benzo[c]cromen-6-ona (48,5%), 2-fluoro-7,9-diidroxi-6H-benzo[c]cromen-6-ona (69,0%), 2-metil-6Hbenzo[c]cromen-6-ona (79,0%), 2-cloro- 6H-benzo[c]cromen-6-ona (93,5%), 3-fluoro-6H-benzo[c] cromen-6-ona (97,2%), 2-fluoro-6H-benzo[c]cromen-6-ona (93,3%). Os compostos sintetizados foram caracterizados, utilizando-se espectroscopia no IV, espectrometria de massas, espectroscopia de RMN de 1H e de 13C, além de técnicas bidimensionais de RMN como HETCOR. Para a avaliação da atividade fitotóxica foram testadas apenas três substâncias (7,9-diidroxi-2-metil-6H-benzo[c]cromen-6-ona, 2-cloro-7,9-diidroxi-6H-benzo[c]cromen-6-ona e 2-metil-6H- benzo[c]cromen-6-ona) em virtude da indisponibilidade de cloroplastos frescos na Itália na época em que os demais compostos foram sinteitzados. As três substâncias foram avaliadas por meio da chamada reação de Hill, que mede a capacidade que determinados compostos tem de inibir o transporte de elétrons em uma fotossíntese in vitro, tendo o ferricianeto de potássio como o aceptor não-biológico de elétrons. Para isto, foram utilizados cloroplastos, intactos, isolados de folhas de espinafre (Spinacia oleracea). Dentre as substâncias testadas, duas delas tiveram resultados de inibição bastante expressivos, no qual 2-cloro-7,9-diidroxi-6H- benzo[c]cromen-6-ona e 7,9-diidroxi-2-metil-6H-benzo[c] cromen-6-ona apresentaram valores de IC50 iguais a 7,2 e 22,8 μM, respectivamente.

Alternariol is an aromatic lactone produced by fungal phytopathogenic species of Nimbya and Alternaria. These species are known to cause leaf necrosis that generate the death of the plant, including species of weeds like Alternanthera philoxeroides. Its believed that the phytotoxicity of these fungi is associated with the production of…

Advisors/Committee Members: Luiz Claudio de Almeida Barbosa, Antônio Jacinto Demuner, Elson Santiago de Alvarenga, Célia Regina Alvares Maltha, Robson Ricardo Teixeira, Gaspar Diaz Muñoz.

Subjects/Keywords: Alternariol; Herbicidas; Fungos fitopatogênicos; Acoplamento de Suzuki; QUIMICA ORGANICA; Alternariol; Herbicides; Plant pathogenic fungi; Suzuki coupling reaction

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Geraldo, G. C. (2008). Síntese e avaliação da atividade fitotóxica de análogos ao alternariol. (Thesis). Universidade Federal de Viçosa. Retrieved from http://www.tede.ufv.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=1891

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Geraldo, Guilherme Carvalho. “Síntese e avaliação da atividade fitotóxica de análogos ao alternariol.” 2008. Thesis, Universidade Federal de Viçosa. Accessed March 07, 2021. http://www.tede.ufv.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=1891.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Geraldo, Guilherme Carvalho. “Síntese e avaliação da atividade fitotóxica de análogos ao alternariol.” 2008. Web. 07 Mar 2021.

Vancouver:

Geraldo GC. Síntese e avaliação da atividade fitotóxica de análogos ao alternariol. [Internet] [Thesis]. Universidade Federal de Viçosa; 2008. [cited 2021 Mar 07]. Available from: http://www.tede.ufv.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=1891.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Geraldo GC. Síntese e avaliação da atividade fitotóxica de análogos ao alternariol. [Thesis]. Universidade Federal de Viçosa; 2008. Available from: http://www.tede.ufv.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=1891

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Vilnius University

10. Dodonova, Jelena. Pirolo[2,3-d]pirimidino oligoarilenų sintezė ir fotofizikinės savybės.

Degree: PhD, Chemistry, 2012, Vilnius University

URL: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2012~D_20120917_092617-49864 ;

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Šio darbo tikslas buvo susintetinti pirolo[2,3-d]pirimidino oligoarilenus ir ištirti jų fotofizikines savybes. Rezultate, ištirta 2,4-dichlorpirolo[2,3-d]pirimidino Suzuki reakcija su arilborono rūgštimis bei susintetinti nauji 4-aril- ir… (more)

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Šio darbo tikslas buvo susintetinti pirolo[2,3-d]pirimidino oligoarilenus ir ištirti jų fotofizikines savybes. Rezultate, ištirta 2,4-dichlorpirolo[2,3-d]pirimidino Suzuki reakcija su arilborono rūgštimis bei susintetinti nauji 4-aril- ir 2,4-diarilpirolo[2,3-d]pirimidinai. Pasiūlyta katalitinė sistema bei surastos reakcijos sąlygos, leidžiančios regioselektyviai atlikti Suzuki kryžminio jungimo reakciją 2,4-dichlorpirolo[2,3-d]pirimidine. Ištirta variu(I) katalizuojama N-arilinimo reakcija tarp 2,4-diarilpirolo[2,3-d]pirimidinų ir įvairių arilhalogenidų, dihalokarbazolų ir dihalofluorenų bei susintetinti 2,4,7-triarilpirolo[2,3-d]pirimidinai, bis(pirolo[2,3-d]pirimidin-7-il)karbazolai ir atitinkami fluorenai. Sukurtas būdas, leidžiantis sintetinti pirolo[2,3-d]pirimidinus su įvairiais pakaitais 2-, 4- ir 7-oje heterociklo padėtyse. Pirmą kartą nustatyta, kad pirolo[2,3-d]pirimidino oligoarilenai pasižymi mėlyna-UV fluorescencija tirpale ir kietame būvyje. Ištirta arilgrupių struktūros, padėties pirolo[2,3-d]pirimidino žiede bei pi-konjuguotos sistemos dydžio įtaka junginių fotoliuminescencinėms savybėms. Nustatyta, kad kai kurie pirolo[2,3-d]pirimidino oligoarilenai pasižymi teigiamu solvatofluorochrominiu efektu, sudaro nanoagregatus tetrahidrofurano/vandens mišinyje. Nustatyta, kad molekulių agregacija indukuoja emisijos padidėjimą. Parodyta, kad pirolo[2,3-d]pirimidino oligomerai su išplėsta pi-konjuguota sistema efektyviau fluorescuoja kietame būvyje nei tirpale.

The main goal of the present work was to synthesize pyrrolo[2,3-d]pyrimidine core based oligoarylenes and to evaluate their photophysical properties. As a result, the Suzuki reaction of 2,4-dichloropyrrolo[2,3-d]pyrimidine with arylboronic acids was studied and novel 4-aryl- and 2,4-diarylpyrrolo[2,3-d]pyrimidines were synthesized. The reaction conditions including an effective catalyst system for the Suzuki cross-coupling reaction were proposed to achieve site-selectivity of the reaction studied. A general approach for the preparation of 2,4,7-triarylpyrrolo[2,3-d]pyrimidines, bis(pyrrolo[2,3-d]pyrimidin-7-yl)carbazoles and -fluorenes were developed by copper-catalyzed N-arylation reaction of 2,4-diarylpyrrolo[2,3-d]pyrimidines with aryl halogenides, dihalocarbazoles or dihalofluorenes. Synthetic strategies leading to pyrrolo[2,3-d]pyrimidines with different aryl moieties in positions 2, 4 and 7 of the heterocycle were studied and an efficient method for their synthesis was developed. The synthesized pyrrolo[2,3-d]pyrimidine-core based oligoarylenes were found to exhibit blue-UV fluorescence in solution and in solid state. Influence of structure of aryl groups, their position in the pyrrolo[2,3-d]pyrimidine nucleous and extent of pi-conjugated aromatic system on the photoluminescent characteristics were evaluated. Some pyrrolo[2,3-d]pyrimidine derivatives were found to exhibit positive solvatofluorochromism and to form nanoaggregates in THF/water mixtures with aggregation... [to full text]

Advisors/Committee Members: Vainilavičius, Povilas (Doctoral dissertation committee chair), Butkus, Eugenijus (Doctoral dissertation committee member), Malinauskas, Albertas (Doctoral dissertation committee member), Mickevičius, Vytautas (Doctoral dissertation committee member), Undzėnas, Algimantas (Doctoral dissertation committee member), Burbulienė, Milda Malvina (Doctoral dissertation opponent), Getautis, Vytautas (Doctoral dissertation opponent), Tumkevičius, Sigitas (Doctoral dissertation supervisor).

Subjects/Keywords: Pirolo[2; 3-d]pirimidinas; Fluorescencija; Suzuki reakcija; N-arilinimas; Pyrrolo[2; 3-d]pyrimidine; Fluorescence; Suzuki reaction; N-arylation

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Dodonova, J. (2012). Pirolo[2,3-d]pirimidino oligoarilenų sintezė ir fotofizikinės savybės. (Doctoral Dissertation). Vilnius University. Retrieved from http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2012~D_20120917_092617-49864 ;

Chicago Manual of Style (16^th Edition):

Dodonova, Jelena. “Pirolo[2,3-d]pirimidino oligoarilenų sintezė ir fotofizikinės savybės.” 2012. Doctoral Dissertation, Vilnius University. Accessed March 07, 2021. http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2012~D_20120917_092617-49864 ;.

MLA Handbook (7^th Edition):

Dodonova, Jelena. “Pirolo[2,3-d]pirimidino oligoarilenų sintezė ir fotofizikinės savybės.” 2012. Web. 07 Mar 2021.

Vancouver:

Dodonova J. Pirolo[2,3-d]pirimidino oligoarilenų sintezė ir fotofizikinės savybės. [Internet] [Doctoral dissertation]. Vilnius University; 2012. [cited 2021 Mar 07]. Available from: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2012~D_20120917_092617-49864 ;.

Council of Science Editors:

Dodonova J. Pirolo[2,3-d]pirimidino oligoarilenų sintezė ir fotofizikinės savybės. [Doctoral Dissertation]. Vilnius University; 2012. Available from: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2012~D_20120917_092617-49864 ;

Vilnius University

11. Dodonova, Jelena. Synthesis and photophysical properties of pyrrolo[2,3-d]pyrimidine-core based oligoarylenes.

Degree: Dissertation, Chemistry, 2012, Vilnius University

URL: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2012~D_20120917_092627-68184 ;

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The main goal of the present work was to synthesize pyrrolo[2,3-d]pyrimidine core based oligoarylenes and to evaluate their photophysical properties. As a result, the Suzuki… (more)

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The main goal of the present work was to synthesize pyrrolo[2,3-d]pyrimidine core based oligoarylenes and to evaluate their photophysical properties. As a result, the Suzuki reaction of 2,4-dichloropyrrolo[2,3-d]pyrimidine with arylboronic acids was studied and novel 4-aryl- and 2,4-diarylpyrrolo[2,3-d]pyrimidines were synthesized. The reaction conditions including an effective catalyst system for the Suzuki cross-coupling reaction were proposed to achieve site-selectivity of the reaction studied. A general approach for the preparation of 2,4,7-triarylpyrrolo[2,3-d]pyrimidines, bis(pyrrolo[2,3-d]pyrimidin-7-yl)carbazoles and -fluorenes were developed by copper-catalyzed N-arylation reaction of 2,4-diarylpyrrolo[2,3-d]pyrimidines with aryl halogenides, dihalocarbazoles or dihalofluorenes. Synthetic strategies leading to pyrrolo[2,3-d]pyrimidines with different aryl moieties in positions 2, 4 and 7 of the heterocycle were studied and an efficient method for their synthesis was developed. The synthesized pyrrolo[2,3-d]pyrimidine-core based oligoarylenes were found to exhibit blue-UV fluorescence in solution and in solid state. Influence of structure of aryl groups, their position in the pyrrolo[2,3-d]pyrimidine nucleous and extent of pi-conjugated aromatic system on the photoluminescent characteristics were evaluated. Some pyrrolo[2,3-d]pyrimidine derivatives were found to exhibit positive solvatofluorochromism and to form nanoaggregates in THF/water mixtures with aggregation... [to full text]

Šio darbo tikslas buvo susintetinti pirolo[2,3-d]pirimidino oligoarilenus ir ištirti jų fotofizikines savybes. Rezultate, ištirta 2,4-dichlorpirolo[2,3-d]pirimidino Suzuki reakcija su arilborono rūgštimis bei susintetinti nauji 4-aril- ir 2,4-diarilpirolo[2,3-d]pirimidinai. Pasiūlyta katalitinė sistema bei surastos reakcijos sąlygos, leidžiančios regioselektyviai atlikti Suzuki kryžminio jungimo reakciją 2,4-dichlorpirolo[2,3-d]pirimidine. Ištirta variu(I) katalizuojama N-arilinimo reakcija tarp 2,4-diarilpirolo[2,3-d]pirimidinų ir įvairių arilhalogenidų, dihalokarbazolų ir dihalofluorenų bei susintetinti 2,4,7-triarilpirolo[2,3-d]pirimidinai, bis(pirolo[2,3-d]pirimidin-7-il)karbazolai ir atitinkami fluorenai. Sukurtas būdas, leidžiantis sintetinti pirolo[2,3-d]pirimidinus su įvairiais pakaitais 2-, 4- ir 7-oje heterociklo padėtyse. Pirmą kartą nustatyta, kad pirolo[2,3-d]pirimidino oligoarilenai pasižymi mėlyna-UV fluorescencija tirpale ir kietame būvyje. Ištirta arilgrupių struktūros, padėties pirolo[2,3-d]pirimidino žiede bei pi-konjuguotos sistemos dydžio įtaka junginių fotoliuminescencinėms savybėms. Nustatyta, kad kai kurie pirolo[2,3-d]pirimidino oligoarilenai pasižymi teigiamu solvatofluorochrominiu efektu, sudaro nanoagregatus tetrahidrofurano/vandens mišinyje. Nustatyta, kad molekulių agregacija indukuoja emisijos padidėjimą. Parodyta, kad pirolo[2,3-d]pirimidino oligomerai su išplėsta pi-konjuguota sistema efektyviau fluorescuoja kietame būvyje nei tirpale.

Advisors/Committee Members: Vainilavičius, Povilas (Doctoral dissertation committee chair), Butkus, Eugenijus (Doctoral dissertation committee member), Malinauskas, Albertas (Doctoral dissertation committee member), Mickevičius, Vytautas (Doctoral dissertation committee member), Undzėnas, Algimantas (Doctoral dissertation committee member), Burbulienė, Milda Malvina (Doctoral dissertation opponent), Getautis, Vytautas (Doctoral dissertation opponent), Tumkevičius, Sigitas (Doctoral dissertation supervisor).

Subjects/Keywords: Pyrrolo[2; 3-d]pyrimidine; Fluorescence; Suzuki reaction; N-arylation; Pirolo[2; 3-d]pirimidinas; Fluorescencija; Suzuki reakcija; N-arilinimas

Record Details Similar Records Cite « Share

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Dodonova, J. (2012). Synthesis and photophysical properties of pyrrolo[2,3-d]pyrimidine-core based oligoarylenes. (Doctoral Dissertation). Vilnius University. Retrieved from http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2012~D_20120917_092627-68184 ;

Chicago Manual of Style (16^th Edition):

Dodonova, Jelena. “Synthesis and photophysical properties of pyrrolo[2,3-d]pyrimidine-core based oligoarylenes.” 2012. Doctoral Dissertation, Vilnius University. Accessed March 07, 2021. http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2012~D_20120917_092627-68184 ;.

MLA Handbook (7^th Edition):

Dodonova, Jelena. “Synthesis and photophysical properties of pyrrolo[2,3-d]pyrimidine-core based oligoarylenes.” 2012. Web. 07 Mar 2021.

Vancouver:

Dodonova J. Synthesis and photophysical properties of pyrrolo[2,3-d]pyrimidine-core based oligoarylenes. [Internet] [Doctoral dissertation]. Vilnius University; 2012. [cited 2021 Mar 07]. Available from: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2012~D_20120917_092627-68184 ;.

Council of Science Editors:

Dodonova J. Synthesis and photophysical properties of pyrrolo[2,3-d]pyrimidine-core based oligoarylenes. [Doctoral Dissertation]. Vilnius University; 2012. Available from: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2012~D_20120917_092627-68184 ;

12. François, Benjamin. Utilisation d’organoboranes fonctionnalisés pour la construction de structures polycycliques : Functionalized organoboron compounds for the synthesis of polycyclic scaffolds.

Degree: Docteur es, Chimie moléculaire et macromoléculaire, 2018, Rennes 1

URL: http://www.theses.fr/2018REN1S114

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Les composés organoborés constituent des outils remarquables en synthèse organique de par leur chimie très diversifiée. Les travaux présentés dans ce mémoire abordent de nouveaux… (more)

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Les composés organoborés constituent des outils remarquables en synthèse organique de par leur chimie très diversifiée. Les travaux présentés dans ce mémoire abordent de nouveaux aspects de leur réactivité. Une méthode de synthèse rapide et efficace de 9-hydroxyfluorènes est décrite via une séquence tandem Suzuki/ aldolisation phénolique. Ce processus a été ensuite étendu aux 9-aminofluorènes en ajoutant simplement comme troisième partenaire diverses amines au milieu réactionnel. Des hypothèses mécanistiques sont proposées pour rationaliser ces résultats expérimentaux. Dans une deuxième partie, est présentée une étude articulée autour de la mise en œuvre de réactions ène sur des diènes borylés 1,3. Les produits ainsi obtenus sont ensuite utilisés comme intermédiaires clé de structures polycycliques plus complexes. Enfin, le troisième chapitre est consacré à une nouvelle voie d'accès aux pyrroles C-fusionnés à partir de diènes cycliques borylés, ces derniers étant préparés par hydroboration d'énynes, bora-Wittig ou métathèse. Une grande diversité structurale est alors accessible à partir de ces précurseurs d'accès aisé.

Organoboron compounds are remarkable tools in organic synthesis due to their very diversified chemistry. The work presented in this thesis addresses new aspects of their reactivity. A rapid and efficient synthesis of 9-hydroxyfluorenes is described via a tandem Suzuki/phenol aldolisation sequence. This process was then extended to 9-aminofluorenes by simply adding various amines to the reaction medium as the third partner. Mechanistic hypotheses are proposed to rationalize these experimental results. In a second part, was presented a study articulated around the implementation of ene reactions on borylated 1,3-dienes. The products thus obtained are then used as key intermediates of more complex polycyclic scaffolds. Finally, the third chapter is dedicated to a new access to C-fused pyrroles from borylated cyclic dienes, the latter being prepared by hydroboration of enynes, boron-Wittig or metathesis reactions. A great structural diversity is then accessible from these easily prepared precursors.

Advisors/Committee Members: Berrée, Fabienne (thesis director), Carboni, Bertrand (thesis director).

Subjects/Keywords: Synthèse; Cascade; Organoboranes; Couplage de Suzuki; Réaction ène; Pyrrole; Synthesis; Cascade; Organoboranes; Suzuki coupling; Ene reaction; Pyrrole

Record Details Similar Records Cite « Share

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

François, B. (2018). Utilisation d’organoboranes fonctionnalisés pour la construction de structures polycycliques : Functionalized organoboron compounds for the synthesis of polycyclic scaffolds. (Doctoral Dissertation). Rennes 1. Retrieved from http://www.theses.fr/2018REN1S114

Chicago Manual of Style (16^th Edition):

François, Benjamin. “Utilisation d’organoboranes fonctionnalisés pour la construction de structures polycycliques : Functionalized organoboron compounds for the synthesis of polycyclic scaffolds.” 2018. Doctoral Dissertation, Rennes 1. Accessed March 07, 2021. http://www.theses.fr/2018REN1S114.

MLA Handbook (7^th Edition):

François, Benjamin. “Utilisation d’organoboranes fonctionnalisés pour la construction de structures polycycliques : Functionalized organoboron compounds for the synthesis of polycyclic scaffolds.” 2018. Web. 07 Mar 2021.

Vancouver:

François B. Utilisation d’organoboranes fonctionnalisés pour la construction de structures polycycliques : Functionalized organoboron compounds for the synthesis of polycyclic scaffolds. [Internet] [Doctoral dissertation]. Rennes 1; 2018. [cited 2021 Mar 07]. Available from: http://www.theses.fr/2018REN1S114.

Council of Science Editors:

François B. Utilisation d’organoboranes fonctionnalisés pour la construction de structures polycycliques : Functionalized organoboron compounds for the synthesis of polycyclic scaffolds. [Doctoral Dissertation]. Rennes 1; 2018. Available from: http://www.theses.fr/2018REN1S114

13. Fodor, Anna. Heterogeneous metal-catalysed C-C coupling reactions : research and development : Réactions de couplage C-C réalisée par catalyse hétérogène : recherche et développement.

Degree: Docteur es, Chimie organique, minérale, industrielle, 2016, Poitiers; Budapesti Műszaki és Gazdaságtudományi Egyetem (Budapest)

URL: http://www.theses.fr/2016POIT2256

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Des nouveaux catalyseurs bimétalliques à base de palladium et de cuivre ont été développés. Deux voies de préparation ont été testées : l'imprégnation successive (TSI)… (more)

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Des nouveaux catalyseurs bimétalliques à base de palladium et de cuivre ont été développés. Deux voies de préparation ont été testées : l'imprégnation successive (TSI) et la co-imprégnation (CI) en utilisant la zéolithe 4Å (4A) et l'oxyde mixte MgAlxOy comme support. Les catalyseurs ont été caractérisés à l'état frais et testés dans la réaction de couplage Suzuki–Miyaura afin de comparer leurs activités, sélectivités et stabilités. L'étude de stabilité nous a montré que le catalyseur Cu-Pd-4A-TSI restait actif pendant six cycles alors que l'activité du catalyseur Cu-Pd-4A-CI diminuait. Sur le support MgAlxOy, le catalyseur CI était stable pendant six cycles contrairement au catalyseur TSI. Nous avons montré que le point clé pour l'obtention d'une bonne activité et stabilité est la présence de la phase active correspondant à l'alliage Cu/Pd 1/1 identifiée grâce à la caractérisation des catalyseurs et ce quelle que soit la méthode de préparation des catalyseurs. Une différence cruciale existe entre les catalyseurs supportés sur MgAlxOy et 4A : le catalyseur Cu–Pd supporté sur MgAlxOy permet de réduire le temps de réaction de moitié pour une même conversion par rapport à Cu-Pd-4A-TSI. De plus, l'utilisation d'un support plus basique permet, dans une certaine mesure, la diminution de la quantité de la base ajoutée durant la réaction. La réaction Petasis-borono Mannich a été aussi effectuée avec succès sur ces catalyseurs.

New bimetallic palladium/copper catalysts were developed by successive impregnation (TSI) and co-impregnation (CI) on 4Å molecular sieve (4A) and MgAlO mixed oxides supports. The fresh catalysts were characterised and tested in the Suzuki–Miyaura reaction to test their activity, selectivity and stability. It was observed that while the Cu-Pd-4A-TSI catalyst kept its activity during six cycles that of the Cu-Pd-4A-CI dropped. On MgAlO support the catalyst prepared with CI proved to be stable even for six runs contrary to TSI. The active phase of the reaction – namely the Cu–Pd alloy with atomic ratio 1:1 - was determined with the help of catalyst characterisation of the recovered catalysts. This observation confirms that whatever the way of preparation or the support is, the key-point is the presence of Pd-Cu 1:1 particles to enhance the catalytic performances. A crucial difference between the MgAlO and 4A supported catalyst was found in the reaction time necessary for the Suzuki–Miyaura reaction. With the Cu-Pd-MgAl-CI catalyst the reaction time could be reduced to thirty minutes contrary to one hour with Cu-Pd-4A-TSI. Moreover it was concluded that with a more basic support the reduction of the quantity of the base was possible however it brought slightly decreasing yield. The Petasis-borono Mannich reaction was also performed in the presence of each mono-and bimetallic catalysts.

Advisors/Committee Members: Pirault-Roy, Laurence (thesis director), Hell, Zoltán (thesis director).

Subjects/Keywords: Catalyse bimétallique; Alliage cuivre-Palladium; Réaction de Suzuki; Réaction de Petasis; Effet du support; Bimetallic catalysis; Copper-Palladium alloy; Suzuki reaction; Petasis reaction; Effect of the support; 541.395

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Fodor, A. (2016). Heterogeneous metal-catalysed C-C coupling reactions : research and development : Réactions de couplage C-C réalisée par catalyse hétérogène : recherche et développement. (Doctoral Dissertation). Poitiers; Budapesti Műszaki és Gazdaságtudományi Egyetem (Budapest). Retrieved from http://www.theses.fr/2016POIT2256

Chicago Manual of Style (16^th Edition):

Fodor, Anna. “Heterogeneous metal-catalysed C-C coupling reactions : research and development : Réactions de couplage C-C réalisée par catalyse hétérogène : recherche et développement.” 2016. Doctoral Dissertation, Poitiers; Budapesti Műszaki és Gazdaságtudományi Egyetem (Budapest). Accessed March 07, 2021. http://www.theses.fr/2016POIT2256.

MLA Handbook (7^th Edition):

Fodor, Anna. “Heterogeneous metal-catalysed C-C coupling reactions : research and development : Réactions de couplage C-C réalisée par catalyse hétérogène : recherche et développement.” 2016. Web. 07 Mar 2021.

Vancouver:

Fodor A. Heterogeneous metal-catalysed C-C coupling reactions : research and development : Réactions de couplage C-C réalisée par catalyse hétérogène : recherche et développement. [Internet] [Doctoral dissertation]. Poitiers; Budapesti Műszaki és Gazdaságtudományi Egyetem (Budapest); 2016. [cited 2021 Mar 07]. Available from: http://www.theses.fr/2016POIT2256.

Council of Science Editors:

Fodor A. Heterogeneous metal-catalysed C-C coupling reactions : research and development : Réactions de couplage C-C réalisée par catalyse hétérogène : recherche et développement. [Doctoral Dissertation]. Poitiers; Budapesti Műszaki és Gazdaságtudományi Egyetem (Budapest); 2016. Available from: http://www.theses.fr/2016POIT2256

NSYSU

14. Huang, Hao-ping. Palladium(II)-Catalyzed Direct Ortho Arylation of 4-Methyl-N-phenylpyridin-2-amines via Suzuki-Miyaura Type C-H Bond Activation/C-C Bond Coupling.

Degree: Master, Chemistry, 2013, NSYSU

URL: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0406113-201051

► The direct ortho arylation of 4-methyl-N-phenylpyridin-2-amines via palladium(II)-catalyzed C-H activation is described. Treatment of 4-methyl-N-phenylpyridin-2-amine with potassium aryltrifluoroborate using ten mol % of Pd(OAc)2 as… (more)

Subjects/Keywords: palladium; C-H bond activation; potassium aryltrifluoroborate; Suzuki-Miyaura cross-coupling reaction

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APA (6^th Edition):

Huang, H. (2013). Palladium(II)-Catalyzed Direct Ortho Arylation of 4-Methyl-N-phenylpyridin-2-amines via Suzuki-Miyaura Type C-H Bond Activation/C-C Bond Coupling. (Thesis). NSYSU. Retrieved from http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0406113-201051

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Huang, Hao-ping. “Palladium(II)-Catalyzed Direct Ortho Arylation of 4-Methyl-N-phenylpyridin-2-amines via Suzuki-Miyaura Type C-H Bond Activation/C-C Bond Coupling.” 2013. Thesis, NSYSU. Accessed March 07, 2021. http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0406113-201051.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Huang, Hao-ping. “Palladium(II)-Catalyzed Direct Ortho Arylation of 4-Methyl-N-phenylpyridin-2-amines via Suzuki-Miyaura Type C-H Bond Activation/C-C Bond Coupling.” 2013. Web. 07 Mar 2021.

Vancouver:

Huang H. Palladium(II)-Catalyzed Direct Ortho Arylation of 4-Methyl-N-phenylpyridin-2-amines via Suzuki-Miyaura Type C-H Bond Activation/C-C Bond Coupling. [Internet] [Thesis]. NSYSU; 2013. [cited 2021 Mar 07]. Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0406113-201051.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Huang H. Palladium(II)-Catalyzed Direct Ortho Arylation of 4-Methyl-N-phenylpyridin-2-amines via Suzuki-Miyaura Type C-H Bond Activation/C-C Bond Coupling. [Thesis]. NSYSU; 2013. Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0406113-201051

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

NSYSU

15. Wu, Chung-chiu. Palladium (II)-Catalyzed Ortho Arylation of 9-(Pyridin-2-yl)-9H-carbazoles via C-H Bond Activation And Mechanistic Investigation.

Degree: Master, Chemistry, 2012, NSYSU

URL: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0709112-170941

► A one-pot synthesis of ortho-arylated 9-(pyridin-2-yl)-9H-carbazoles via C-H bond activation, in which palladium(II)-catalyzed cross-coupling of 9-(pyridin-2-yl)-9H-carbazoles with potassium aryltrifluoroborates is presented. Silver nitrate and tert-butanol… (more)

Subjects/Keywords: potassium aryltrifluoroborate; palladium catalysis; C-H bond activation; carbazole; Suzuki-Miyaura coupling reaction

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APA (6^th Edition):

Wu, C. (2012). Palladium (II)-Catalyzed Ortho Arylation of 9-(Pyridin-2-yl)-9H-carbazoles via C-H Bond Activation And Mechanistic Investigation. (Thesis). NSYSU. Retrieved from http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0709112-170941

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Wu, Chung-chiu. “Palladium (II)-Catalyzed Ortho Arylation of 9-(Pyridin-2-yl)-9H-carbazoles via C-H Bond Activation And Mechanistic Investigation.” 2012. Thesis, NSYSU. Accessed March 07, 2021. http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0709112-170941.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Wu, Chung-chiu. “Palladium (II)-Catalyzed Ortho Arylation of 9-(Pyridin-2-yl)-9H-carbazoles via C-H Bond Activation And Mechanistic Investigation.” 2012. Web. 07 Mar 2021.

Vancouver:

Wu C. Palladium (II)-Catalyzed Ortho Arylation of 9-(Pyridin-2-yl)-9H-carbazoles via C-H Bond Activation And Mechanistic Investigation. [Internet] [Thesis]. NSYSU; 2012. [cited 2021 Mar 07]. Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0709112-170941.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Wu C. Palladium (II)-Catalyzed Ortho Arylation of 9-(Pyridin-2-yl)-9H-carbazoles via C-H Bond Activation And Mechanistic Investigation. [Thesis]. NSYSU; 2012. Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0709112-170941

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Alberta

16. Lee, Jack C. H. Preparation and Synthetic Applications of Chiral Alkyl Boronates and Unsaturated Alkenyl Boronates.

Degree: PhD, Department of Chemistry, 2013, University of Alberta

URL: https://era.library.ualberta.ca/files/qn59q550n

► As Organic Chemistry evolves into the 21st Century, the goal of this discipline has altered dramatically from merely accessing target molecules to efficiently synthesizing these… (more)

▼ As Organic Chemistry evolves into the 21st Century, the goal of this discipline has altered dramatically from merely accessing target molecules to efficiently synthesizing these compounds with minimization of non-strategic functional group manipulations and interconversions. Organoboron reagents represent one of the potential solutions towards reaching this goal. These versatile compounds can either be used to construct the desired carbon−carbon bond through various cross-coupling reactions, or be converted directly to the desired functionality through different chemical reactions. Direct transformations make interconversions between different functional groups unnecessary, thus making the overall process step-economical. In this thesis, several synthetic methods were developed to synthesize chiral alkyl boronates or alkenyl boronates through metal-catalyzed chemical transformations. These methodologies are based on early introduction strategy which applies well-established synthetic protocols to substrates with a pre-installed boronyl moiety. The subsequent applications of these compounds were also investigated, leading to a variety of synthetically valuable adducts. In order to access novel chiral secondary alkyl boronates, catalytic asymmetric conjugate addition reactions of 3-boronyl -unsaturated esters with Grignard reagents were developed. Chapter 2 describes the details of optimization of this methodology and the applications of the chiral alkyl boronate products. Aiming to explore the intrinsic reactivity of enantioenriched 1,1-diboron compounds, their synthesis was accomplished for the first time by performing asymmetric conjugate borylation on 3-boronyl enoates. The resulting optically enriched 1,1-diboron compounds were found to be excellent cross-coupling partners in Suzuki-Miyaura cross-couplings, leading to chiral alkyl boronates with excellent enantioselectivity. The details of these studies are presented in Chapter 3. In order to conduct a thorough examination of substrate scope in asymmetric conjugate reductions of 3-boronyl-3-aryl -unsaturated esters, a diastereoselective protocol for the preparation of these alkenyl boronates through Heck coupling was developed. In Chapter 4, the optimization of the coupling process, the substrate scope, and the subsequent application of these alkenyl boronates are discussed. Due to the synthetic potential of cyclic alkenyl boronates, new methods for their efficient synthesis are desirable. In Chapter 5, the preparation of novel cyclic alkenyl boronates through gold-catalyzed enyne cycloisomerizations is presented.

Subjects/Keywords: Gold-catalyzed cycloisomerization; Suzuki-Miyaura cross-coupling; Chiral alkyl boronates; Heck reaction; Enantioselective conjugate addition

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Lee, J. C. H. (2013). Preparation and Synthetic Applications of Chiral Alkyl Boronates and Unsaturated Alkenyl Boronates. (Doctoral Dissertation). University of Alberta. Retrieved from https://era.library.ualberta.ca/files/qn59q550n

Chicago Manual of Style (16^th Edition):

Lee, Jack C H. “Preparation and Synthetic Applications of Chiral Alkyl Boronates and Unsaturated Alkenyl Boronates.” 2013. Doctoral Dissertation, University of Alberta. Accessed March 07, 2021. https://era.library.ualberta.ca/files/qn59q550n.

MLA Handbook (7^th Edition):

Lee, Jack C H. “Preparation and Synthetic Applications of Chiral Alkyl Boronates and Unsaturated Alkenyl Boronates.” 2013. Web. 07 Mar 2021.

Vancouver:

Lee JCH. Preparation and Synthetic Applications of Chiral Alkyl Boronates and Unsaturated Alkenyl Boronates. [Internet] [Doctoral dissertation]. University of Alberta; 2013. [cited 2021 Mar 07]. Available from: https://era.library.ualberta.ca/files/qn59q550n.

Council of Science Editors:

Lee JCH. Preparation and Synthetic Applications of Chiral Alkyl Boronates and Unsaturated Alkenyl Boronates. [Doctoral Dissertation]. University of Alberta; 2013. Available from: https://era.library.ualberta.ca/files/qn59q550n

Virginia Commonwealth University

17. Yang, Yuan. Graphene as a Solid-state Ligand for Palladium Catalyzed Cross-coupling Reactions.

Degree: PhD, Engineering, 2018, Virginia Commonwealth University

URL: https://doi.org/10.25772/562K-7355 ; https://scholarscompass.vcu.edu/etd/5488

► Palladium-catalyzed carbon-carbon cross-coupling reactions have emerged a broadly useful, selective and widely applicable method to synthesize pharmaceutical active ingredients. As currently practiced in the… (more)

▼ Palladium-catalyzed carbon-carbon cross-coupling reactions have emerged a broadly useful, selective and widely applicable method to synthesize pharmaceutical active ingredients. As currently practiced in the pharmaceutical industry, homogeneous Pd catalysts are typically used in cross-coupling reactions. The rational development of heterogeneous catalysts for cross-coupling reactions is critical for overcoming the major drawbacks of homogeneous catalysis including difficulties in the separation, purification, and quality control process in drug production. In order to apply heterogeneous catalysis to flow reactors that may overcome this limitation, the catalyst must be strongly bound to a support, highly stable with respect to leaching, and highly active. While the primary role of supports in catalysis has been to anchor metal particles to prevent sintering and leaching, supports can also activate catalytic processes. In this study, by using a xi combined theoretical and experimental method, we probed the effect of graphene as support in the complex reaction cycle of Suzuki reactions. The density functional theory study provides a fundamental understanding of how a graphene support strongly binds the Pd nanoparticles and act as both an efficient charge donor and acceptor in oxidation and reduction reaction steps. Theoretical investigations prove that the Pd-graphene interaction promotes electron flow between the metal cluster and the defected graphene to reduce reaction barrier. The ability for graphene to both accept and donate charge makes graphene an unusually suitable support for multi-step catalytic processes that involve both oxidation and reduction steps. The computer-aided catalyst design with the atomic precise accuracy demonstrates the Pd/graphene catalyst can be further optimized and the first-row transition metal nanoparticles have great potential to replace Pd to catalyze the Suzuki reaction. The corresponding experimental study shows that the method to immobilize the Pd nanoparticles on the graphene is crucial to increasing the reactivity and stability of the resulted catalyst. A comparison of the activation energy and turn over frequency for a series of supported and homogeneous catalysts indicates that exposing palladium-graphene to defect inducing microwave radiation results in dramatically lower activation energies and higher turnover frequencies. Furthermore, the heterogeneity tests demonstrate the Suzuki reactions are carried out on the surface of the immobilized Pd nanoparticle agreeing with the theoretical results. A method to engineer the 2-D graphene support to a 3-D structure to minimize the re-stacking and agglomeration of the graphene lattice will also be introduced in this study. Advisors/Committee Members: Frank Gupton, Arthur Reber, Shiv Khanna, Christina Tang, Stephen Fong.

Subjects/Keywords: Graphene Nanocatalysis heterogeneous Suzuki Palladium; Catalysis and Reaction Engineering; Nanoscience and Nanotechnology

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Yang, Y. (2018). Graphene as a Solid-state Ligand for Palladium Catalyzed Cross-coupling Reactions. (Doctoral Dissertation). Virginia Commonwealth University. Retrieved from https://doi.org/10.25772/562K-7355 ; https://scholarscompass.vcu.edu/etd/5488

Chicago Manual of Style (16^th Edition):

Yang, Yuan. “Graphene as a Solid-state Ligand for Palladium Catalyzed Cross-coupling Reactions.” 2018. Doctoral Dissertation, Virginia Commonwealth University. Accessed March 07, 2021. https://doi.org/10.25772/562K-7355 ; https://scholarscompass.vcu.edu/etd/5488.

MLA Handbook (7^th Edition):

Yang, Yuan. “Graphene as a Solid-state Ligand for Palladium Catalyzed Cross-coupling Reactions.” 2018. Web. 07 Mar 2021.

Vancouver:

Yang Y. Graphene as a Solid-state Ligand for Palladium Catalyzed Cross-coupling Reactions. [Internet] [Doctoral dissertation]. Virginia Commonwealth University; 2018. [cited 2021 Mar 07]. Available from: https://doi.org/10.25772/562K-7355 ; https://scholarscompass.vcu.edu/etd/5488.

Council of Science Editors:

Yang Y. Graphene as a Solid-state Ligand for Palladium Catalyzed Cross-coupling Reactions. [Doctoral Dissertation]. Virginia Commonwealth University; 2018. Available from: https://doi.org/10.25772/562K-7355 ; https://scholarscompass.vcu.edu/etd/5488

Univerzitet u Beogradu

18. Aleksić, Jovana. 1980-. 4-oksotiazolidin-2-alkiliden vinil-bromidi i α, α-dibrom-2-metoksiacetofenon : prekursori u sintetički korisnim transformacijama iniciranim retkim halofilnim napadom nukleofila.

Degree: Hemijski fakultet, 2014, Univerzitet u Beogradu

URL: https://fedorabg.bg.ac.rs/fedora/get/o:8119/bdef:Content/get

►

Hemija - Organska hemija / Chemistry - Organic chemistry Datum odbrane: 8.03.2013.

Halofilne reakcije predstavljaju vrstu nukleofilnih supstitucionih reakcija do kojih dolazi kada nukleofil reaguje… (more)

▼

Hemija - Organska hemija / Chemistry - Organic chemistry Datum odbrane: 8.03.2013.

Halofilne reakcije predstavljaju vrstu nukleofilnih supstitucionih reakcija do kojih dolazi kada nukleofil reaguje sa atomom halogena, nakon ega se oslobaa karbanjon kao odlazea grupa. To su relativno rijetke reakcije koje se dešavaju ukoliko je klasina nukleofilna supstitucija (karbofilna reakcija) iz nekog razloga otežana i/ili kada je karbanjon stabilizovan prisustvom elektron-privlanih supstituenata. Cilj ovog rada je bio da se ispitaju halofilne reakcije i njihova sintetika primena na dva sistema: 2-alkiliden-4-oksotiazolidin vinil-bromidima i ,-dibrom-2- metoksiacetofenonu. Znaaj ovih reakcija u sluaju ispitivanih N-nesupstituisanih tiazolidinskih jedinjenja je u dobijanju novih, potencijalno biološki aktivnih C-5 funkcionalizovanih derivata. Ovakvi derivati se ne mogu dobiti direktno reakcionom sekvencom C-5 bromovanje/nukleofilna supstitucija, jer je bromovanje Nnesupstituisanih 2-alkiliden-4-oksotiazolidina visoko regioselektivno i kao proizvodi se dobijaju iskljuivo vinil-bromidi. Znaaj prouavanja ovakvih reakcija u sluaju a,a- dibrom-2-metoksiacetofenona proistie iz injenice da se selektivno a- monobromovanje metil-ketona esto teško postiže, a praeno je stvaranjem a,a-dibromderivata kao sporednih, a ponekad i kao glavnih proizvoda. Mogua kaskadna halofilna/karbofilna reakcija bi omoguila korišenje dibrom-derivata kao sintetikih ekvivalenta monobromida, ime bi se izbegla dodatna faza selektivnog debromovanja radi dobijanja monobrom-derivata, kao znaajnih sintetikih intermedijera. Razliiti neutralni i anjonski nukleofili su uestvovali u halofilnoj reakciji sa tiazolidinskim vinilbromidima dajui tri vrste proizvoda: i) proizvod reduktivnog debromovanja, ii) proizvod supstitucije broma i iii) C-5 funkcionalizovan proizvod. Takoe je pokazano da se ,-dibrom-2-metoksiacetofenon može upotrebiti kao sintetiki ekvivalent a- monobromacetofenona. Pored navedenih halofilnih reakcija, u ovom radu ispitivana je i mogunost izvoenja Suzuki-Miyaura reakcije na vinil-bromidima, kao i mogua regioselektivnost ove reakcije na N-supstituisanom tribrompirazolu, a u cilju dobijanja novih, potencijalno biološki aktivnih jedinjenja. Suzuki-Miyaura reakcija sa derivatima arilbornih kiselina izvedena na vinil-bromidima nije dala oekivani rezultat, ali je uspešno izvedena sa N-supstituisanim tribrompirazolima uz visoku regioselektivnost, pri emu su sintetisani 5-supstituisani 3,4-dibrompirazoli sa 1,1 ekvivalentom arilbornih kiselina, 3,5-disupstituisani 4-brompirazoli sa 2,2 ekvivalenta arilbornih kiselina i 3,4,5- trisupstituisani derivati sa 3,5 ekvivalenata arilbornih kiselina. S obzirom da ispitivani tiazolidini spadaju u grupu push-pull alkena, kod kojih elektronska delokalizacija izmeu donorskih i akceptorskih grupa na dvostrukoj vezi ima znaajan uticaj na njihove osobine i hemijsku reaktivnost, uraena je i kvantifikacija push-pull efekta dvostruke veze.

Advisors/Committee Members: Baranac-Stojanović, Marija, 1971-.

Subjects/Keywords: halophilic reactions; vinyl halides; ; -dibromoacetophenones; Suzuki- Miyaura reaction; push-pull effect; NBO analysis

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Aleksić, J. 1. (2014). 4-oksotiazolidin-2-alkiliden vinil-bromidi i α, α-dibrom-2-metoksiacetofenon : prekursori u sintetički korisnim transformacijama iniciranim retkim halofilnim napadom nukleofila. (Thesis). Univerzitet u Beogradu. Retrieved from https://fedorabg.bg.ac.rs/fedora/get/o:8119/bdef:Content/get

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Aleksić, Jovana 1980-. “4-oksotiazolidin-2-alkiliden vinil-bromidi i α, α-dibrom-2-metoksiacetofenon : prekursori u sintetički korisnim transformacijama iniciranim retkim halofilnim napadom nukleofila.” 2014. Thesis, Univerzitet u Beogradu. Accessed March 07, 2021. https://fedorabg.bg.ac.rs/fedora/get/o:8119/bdef:Content/get.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Aleksić, Jovana 1980-. “4-oksotiazolidin-2-alkiliden vinil-bromidi i α, α-dibrom-2-metoksiacetofenon : prekursori u sintetički korisnim transformacijama iniciranim retkim halofilnim napadom nukleofila.” 2014. Web. 07 Mar 2021.

Vancouver:

Aleksić J1. 4-oksotiazolidin-2-alkiliden vinil-bromidi i α, α-dibrom-2-metoksiacetofenon : prekursori u sintetički korisnim transformacijama iniciranim retkim halofilnim napadom nukleofila. [Internet] [Thesis]. Univerzitet u Beogradu; 2014. [cited 2021 Mar 07]. Available from: https://fedorabg.bg.ac.rs/fedora/get/o:8119/bdef:Content/get.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Aleksić J1. 4-oksotiazolidin-2-alkiliden vinil-bromidi i α, α-dibrom-2-metoksiacetofenon : prekursori u sintetički korisnim transformacijama iniciranim retkim halofilnim napadom nukleofila. [Thesis]. Univerzitet u Beogradu; 2014. Available from: https://fedorabg.bg.ac.rs/fedora/get/o:8119/bdef:Content/get

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Iowa State University

19. Luan, Xuechen. Layered double hydroxide-derived nanomaterials for Suzuki−Miyaura cross-coupling reaction.

Degree: 2019, Iowa State University

URL: https://lib.dr.iastate.edu/etd/17735

► Layered double hydroxide (LDH) is an inorganic solid with a brucite-like structure that is similar to hydrotalcite, which contains two main metal plates and an… (more)

▼ Layered double hydroxide (LDH) is an inorganic solid with a brucite-like structure that is similar to hydrotalcite, which contains two main metal plates and an anion interlayer in between them. The main metal plates contain both trivalent and divalent metal cations that result in positively charged metal plates. The anion interlayer can compensate for the positive charge on metal plates and result in a natural LDH solid. Their high tunability of chemical composition ordered and uniform metal cation dispersion, and well-distributed layered architecture allows them to become a potential source of intermetallic compound’s (IMC) precursor. Layered double hydroxide can be converted to the mixed metal oxide film (layered double oxide, LDO) after high-temperature calcination, which has a large specific surface area and is more thermally stable. The layered double oxide materials that have specific stoichiometry and homogeneity of composition have been applied directly as catalysts or as catalyst supports. Intermetallic compounds are well-known for their particular electronic structures and geometries, which show high activity and selectivity towards various types of heterogeneous catalysis reactions as compared with alloys. Non-precious metal IMCs derived from LDH precursors have attracted research attention because they are low-cost, readily available, and could exhibit meritorious catalytic performance. The synthesizing process of LDH precursors does not involve any toxic organic reagent. Therefore, it is more environmentally friendly than colloidal chemical synthesis methods. We use LDH as a precursor for two research projects. For the first project, we synthesized the single-atomic Pd which immobilized on the Fe3GaMg7 layered double oxide. Single-atom catalysts have attracted significant research interest because of their extremely excellent catalytic efficiency and superior selectivity. The Pd/ Fe3GaMg7 catalyst demonstrates promising activity for the Suzuki coupling reaction of bromobenzene and phenylboronic acid at room temperature （Turn over Frequency = 2312h-1). This catalyst has been recycled five times without a significant loss of catalytic activity. It also indicates high tolerance towards a broad scope of the functional groups on the aryl halogen compounds. For the second project, we synthesized Ni-Ga, Co-In, and Fe-Ga LDH precursors with various metal compositions and generated the corresponding IMCs via the high-temperature reduction in the gas phase.

Subjects/Keywords: Layered double hydroxide; Room temperature; Single atom Palladium; Suzuki coupling reaction; Chemistry

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APA (6^th Edition):

Luan, X. (2019). Layered double hydroxide-derived nanomaterials for Suzuki−Miyaura cross-coupling reaction. (Thesis). Iowa State University. Retrieved from https://lib.dr.iastate.edu/etd/17735

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Luan, Xuechen. “Layered double hydroxide-derived nanomaterials for Suzuki−Miyaura cross-coupling reaction.” 2019. Thesis, Iowa State University. Accessed March 07, 2021. https://lib.dr.iastate.edu/etd/17735.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Luan, Xuechen. “Layered double hydroxide-derived nanomaterials for Suzuki−Miyaura cross-coupling reaction.” 2019. Web. 07 Mar 2021.

Vancouver:

Luan X. Layered double hydroxide-derived nanomaterials for Suzuki−Miyaura cross-coupling reaction. [Internet] [Thesis]. Iowa State University; 2019. [cited 2021 Mar 07]. Available from: https://lib.dr.iastate.edu/etd/17735.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Luan X. Layered double hydroxide-derived nanomaterials for Suzuki−Miyaura cross-coupling reaction. [Thesis]. Iowa State University; 2019. Available from: https://lib.dr.iastate.edu/etd/17735

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Virginia Commonwealth University

20. Brinkley, Kendra W. The Synthesis of Solid Supported Palladium Nanoparticles: Effective Catalysts for Batch and Continuous Cross Coupling Reactions.

Degree: PhD, Engineering, 2015, Virginia Commonwealth University

URL: https://doi.org/10.25772/ND17-CM26 ; https://scholarscompass.vcu.edu/etd/3959

► Catalysis is one of the pillars of the chemical industry. While the use of catalyst is typically recognized in the automobile industry, their impact… (more)

▼ Catalysis is one of the pillars of the chemical industry. While the use of catalyst is typically recognized in the automobile industry, their impact is more widespread as; catalysts are used in the synthesis of 80% of the US commercial chemicals. Despite the improved selectivity provided by catalyst, process inefficiencies still threaten the sustainability of a number of synthesis methods, especially in the pharmaceutical industry. Recyclable solid supported catalysts offer a unique opportunity to address these inefficiencies. Such systems coupled with continuous synthesis techniques, have the potential to significantly reduce the waste to desired product ratio (E-factor) of the production techniques. This research focuses developing sustainable processes to synthesize organic molecules by using continuous synthesis methods. In doing so, solid supported metal catalyst systems were identified, developed, and implemented to assist in the formation of carbon-carbon bonds. Newly developed systems, which utilized metal nanoparticles, showed reactivity and recyclability, comparable to commercially available catalyst. Nanoparticles are emerging as useful materials in a wide variety of applications including catalysis. These applications include pharmaceutical processes by which complex and useful organic molecules can be prepared. As such, an effective and scalable synthesis method is required for the preparation of nanoparticle catalysts with significant control of the particle size, uniform dispersion, and even distribution of nanoparticles when deposited on the surface of a solid support. This project describes the production of palladium nanoparticles on a variety of solid supports and the evaluation of these nanoparticles for cross coupling reactions. This report highlights novel synthesis techniques used in the formation of palladium nanoparticles using traditional batch reactions. The procedures developed for the batch formation of palladium nanoparticles on different solid supports, such as graphene and carbon nanotubes, are initially described. The major drawbacks of these methods are discussed, including limited scalability, variation of nanoparticle characteristics from batch to batch, and technical challenges associated with efficient heating of samples. Furthermore, the necessary conditions and critical parameters to convert the batch synthesis of solid supported palladium nanoparticles to a continuous flow process are presented. This strategy not only alleviates the challenges associated with the robust preparation of the material and the limitations of scalability, but also showcases a new continuous reactor capable of efficient and direct heating of the reaction mixture under microwave irradiation. This strategy was further used in the synthesis of zinc oxide nanoparticles. Particles synthesized using this strategy as well as traditional synthesis methods, were evaluated in the context industrially relevant applications. Advisors/Committee Members: Dr. B.F. Gupton.

Subjects/Keywords: Palladium nanoparticles; Suzuki Reaction; graphene; Catalysis; Continuous Reactions; Carbon nanotubes; Catalysis and Reaction Engineering; Process Control and Systems

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Brinkley, K. W. (2015). The Synthesis of Solid Supported Palladium Nanoparticles: Effective Catalysts for Batch and Continuous Cross Coupling Reactions. (Doctoral Dissertation). Virginia Commonwealth University. Retrieved from https://doi.org/10.25772/ND17-CM26 ; https://scholarscompass.vcu.edu/etd/3959

Chicago Manual of Style (16^th Edition):

Brinkley, Kendra W. “The Synthesis of Solid Supported Palladium Nanoparticles: Effective Catalysts for Batch and Continuous Cross Coupling Reactions.” 2015. Doctoral Dissertation, Virginia Commonwealth University. Accessed March 07, 2021. https://doi.org/10.25772/ND17-CM26 ; https://scholarscompass.vcu.edu/etd/3959.

MLA Handbook (7^th Edition):

Brinkley, Kendra W. “The Synthesis of Solid Supported Palladium Nanoparticles: Effective Catalysts for Batch and Continuous Cross Coupling Reactions.” 2015. Web. 07 Mar 2021.

Vancouver:

Brinkley KW. The Synthesis of Solid Supported Palladium Nanoparticles: Effective Catalysts for Batch and Continuous Cross Coupling Reactions. [Internet] [Doctoral dissertation]. Virginia Commonwealth University; 2015. [cited 2021 Mar 07]. Available from: https://doi.org/10.25772/ND17-CM26 ; https://scholarscompass.vcu.edu/etd/3959.

Council of Science Editors:

Brinkley KW. The Synthesis of Solid Supported Palladium Nanoparticles: Effective Catalysts for Batch and Continuous Cross Coupling Reactions. [Doctoral Dissertation]. Virginia Commonwealth University; 2015. Available from: https://doi.org/10.25772/ND17-CM26 ; https://scholarscompass.vcu.edu/etd/3959

21. Peramo, Arnaud. Modification sélective de protéines en milieu biologique par réaction de Suzuki-Miyaura nanocatalysée : Selective modification of a protein in biological media by nanocatalyzed Suzuki-Miyaura reaction.

Degree: Docteur es, Pharmacotechnie et biopharmacie, 2019, Université Paris-Saclay (ComUE)

URL: http://www.theses.fr/2019SACLS600

►

Les nanotechnologies ont ouvert de nouvelles perspectives pour l’administration ciblée des médicaments. Les approches actuelles en nanomédecine sont basées sur l’encapsulation d’un principe actif dans… (more)

▼

Les nanotechnologies ont ouvert de nouvelles perspectives pour l’administration ciblée des médicaments. Les approches actuelles en nanomédecine sont basées sur l’encapsulation d’un principe actif dans un nano-vecteur. Nous proposons dans ce travail l’utilisation de nanoparticules non plus pour adresser un médicament encapsulé vers sa cible, mais pour manipuler une protéine d’intérêt en milieu biologique, ce qui constitue une nouvelle stratégie thérapeutique. Avec cet objectif, nous avons identifié une formulation de nanoparticules de palladium, stable, non toxique et dotée d’un pouvoir catalytique remarquable de la réaction de Suzuki-Miyaura. Ce nano-catalyseur permet, en utilisant un dérivé du bore approprié, de greffer des résidus aromatiques sur des acides aminés halogénés dans un tampon phosphate à température et pH physiologiques. En parallèle, la formulation sous forme de nanoparticules de calixarenes fonctionnalisés par des complexes carbéniques du palladium a été également étudiée. Ce nano-réacteur permet d’effectuer dans l’eau et à température ambiante une réaction d’arylation d’amino acides halogénés de manière très efficace. Nous montrons qu’il est possible grâce à ces nanoparticules de modifier sélectivement par une liaison covalente, la thyroglobuline, une protéine naturelle halogénée, impliquée dans la maladie de Basedow et dans certains cancers de la thyroïde. L’absence de modèle cellulaire exprimant la protéine nous a conduit à tester la réaction dans un homogénat d’organe provenant de l’exérèse chirurgicale de la thyroïde chez un patient de la maladie de Basedow. Le couplage de la thyroglobuline par réaction de Suzuki-Miyaura a pu être détecté par analyse protéomique grâce au marquage par un cycle aromatique simple, et par western blot à l’aide d’une sonde biotine autorisant une détection par immuno-essai. En conclusion, la thèse apporte la démonstration de la formation sélective d’une liaison C-C sur une protéine par des nanoparticules de palladium dans un milieu biologique complexe et en conditions physiologiques. Ces résultats pourraient ouvrir la voie à de nouvelles options thérapeutiques permettant de controler le taux de thyroglobuline dans le cas d’une dérégulation hormonale.

Nanotechnology has opened up new perspectives for targeted drug delivery in the treatment of severe diseases. Current approaches in nanomedicine are based on the encapsulation of an active drug in a nanocarrier. In the present study, we have used nanoparticles not to address an encapsulated drug to a target tissue, but for manipulating a protein of interest in a complex biological medium. With this aim, we have identified a stable, non-toxic palladium nanoparticle formulation, embedding a remarkable catalytic activity on the Suzuki-Miyaura reaction. This nano-catalyst allows by using an appropriate boron derivative to couple aromatic residues onto halogenated amino acids in a phosphate buffer at physiological pH. By the same way, the formulation as nanoparticles of calixarene derivatives functionalized with palladium…

Advisors/Committee Members: Couvreur, Patrick (thesis director), Desmaële, Didier (thesis director).

Subjects/Keywords: Palladium nanoparticules; Réaction de Suzuki-Myaura; Chimie in vivo; Thyroglobuline; Protémoque; Palladium nanoparticles; Suzuki-Myaura cross-Coupling reaction; In vivo chemistry; Thyroglobulin; Proteomic

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Peramo, A. (2019). Modification sélective de protéines en milieu biologique par réaction de Suzuki-Miyaura nanocatalysée : Selective modification of a protein in biological media by nanocatalyzed Suzuki-Miyaura reaction. (Doctoral Dissertation). Université Paris-Saclay (ComUE). Retrieved from http://www.theses.fr/2019SACLS600

Chicago Manual of Style (16^th Edition):

Peramo, Arnaud. “Modification sélective de protéines en milieu biologique par réaction de Suzuki-Miyaura nanocatalysée : Selective modification of a protein in biological media by nanocatalyzed Suzuki-Miyaura reaction.” 2019. Doctoral Dissertation, Université Paris-Saclay (ComUE). Accessed March 07, 2021. http://www.theses.fr/2019SACLS600.

MLA Handbook (7^th Edition):

Peramo, Arnaud. “Modification sélective de protéines en milieu biologique par réaction de Suzuki-Miyaura nanocatalysée : Selective modification of a protein in biological media by nanocatalyzed Suzuki-Miyaura reaction.” 2019. Web. 07 Mar 2021.

Vancouver:

Peramo A. Modification sélective de protéines en milieu biologique par réaction de Suzuki-Miyaura nanocatalysée : Selective modification of a protein in biological media by nanocatalyzed Suzuki-Miyaura reaction. [Internet] [Doctoral dissertation]. Université Paris-Saclay (ComUE); 2019. [cited 2021 Mar 07]. Available from: http://www.theses.fr/2019SACLS600.

Council of Science Editors:

Peramo A. Modification sélective de protéines en milieu biologique par réaction de Suzuki-Miyaura nanocatalysée : Selective modification of a protein in biological media by nanocatalyzed Suzuki-Miyaura reaction. [Doctoral Dissertation]. Université Paris-Saclay (ComUE); 2019. Available from: http://www.theses.fr/2019SACLS600

University of Victoria

22. Yunker, Lars Peter Erasmus. Real-time mass spectrometric analysis of catalytic reaction mechanisms.

Degree: Department of Chemistry, 2017, University of Victoria

URL: http://hdl.handle.net/1828/8029

► Mass spectrometry was used to study two disparate transformations: in an applied project, the supposed degradation of perfluorooctanesulfonate (PFOS); and in a fundamental study, the… (more)

Subjects/Keywords: Mass spectrometry; Suzuki-Miyaura; online reaction monitoring; electrospray ionization; ESI-MS; perfluorooctane sulfonate; PFOS; transmetallation mechanism; trifluoroborate hydrolysis; suzuki polycondensation; python; MSPT; pressurized sample infusion

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Yunker, L. P. E. (2017). Real-time mass spectrometric analysis of catalytic reaction mechanisms. (Thesis). University of Victoria. Retrieved from http://hdl.handle.net/1828/8029

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Yunker, Lars Peter Erasmus. “Real-time mass spectrometric analysis of catalytic reaction mechanisms.” 2017. Thesis, University of Victoria. Accessed March 07, 2021. http://hdl.handle.net/1828/8029.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Yunker, Lars Peter Erasmus. “Real-time mass spectrometric analysis of catalytic reaction mechanisms.” 2017. Web. 07 Mar 2021.

Vancouver:

Yunker LPE. Real-time mass spectrometric analysis of catalytic reaction mechanisms. [Internet] [Thesis]. University of Victoria; 2017. [cited 2021 Mar 07]. Available from: http://hdl.handle.net/1828/8029.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Yunker LPE. Real-time mass spectrometric analysis of catalytic reaction mechanisms. [Thesis]. University of Victoria; 2017. Available from: http://hdl.handle.net/1828/8029

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Pontifical Catholic University of Rio de Janeiro

23. [No author]. [en] BAMBOO LIGNOCELLULOSIC SUPPORT IMPREGNATED WITH PALLADIUM AND ITS APPLICATION FOR SUZUKI REACTION.

Degree: 2021, Pontifical Catholic University of Rio de Janeiro

URL: http://www.maxwell.vrac.puc-rio.br/Busca_etds.php?strSecao=resultado&nrSeq=51181

►

[pt] A reação de acoplamento C-C de Suzuki, desde a sua descoberta, sempre atraiu o interesse de diversos pesquisadores e encontrou aplicação em diversos campos… (more)

▼

[pt] A reação de acoplamento C-C de Suzuki, desde a sua descoberta, sempre atraiu o interesse de diversos pesquisadores e encontrou aplicação em diversos campos tanto na academia como na indústria. Movidos pelos problemas ambientais que tanto preocupam nossa sociedade e pelos princípios da química verde, criados para guiar os químicos na direção de uma ciência sustentável, pesquisadores tem buscado criar catalisadores eficientes para essa reação, que consigam uma alta seletividade em condições reacionais brandas. O desenvolvimento de catalisadores heterogêneos é motivado pela sua fácil remoção do meio reacional e seu possível reuso para um elevado número de reações. Uma abordagem para criação desses catalisadores é a ancoragem de íons metálicos ou de nanopartículas (Nps) metálicas em suportes que facilitem seu manuseio, remoção e reuso. Neste trabalho foram sintetizadas nanopartículas de paládio (Nps Pd) estabilizadas por carboximetilcelulose (CMC), em cuja síntese foi utilizado o ácido L-ascórbico (AA) como agente redutor. Essas Nps foram caracterizadas por UV-VIS, FT-IR-ATR, DLS, potencial zeta, MEV e EDS. A reação de redução do 4-nitrofenol foi utilizada como teste preliminar para verificar a atividade catalítica dessas Nps e, em diferentes condições, a reação ocorreu com tempos que variaram de 3 a 10 minutos. Depois, foram empregadas três diferentes metodologias para a síntese de Nps Pd que utilizaram a CMC como agente redutor e estabilizador a fim de eliminar o uso do AA. As três Nps sintetizadas foram usadas para catalisar uma reação de acoplamento entre o ácido fenilborônico e o 4-iodofenol com rendimentos de 68-76 por cento em duas horas. As Nps que obtiveram maior rendimento foram escolhidas para dar prosseguimento ao projeto. Foram caracterizadas por UV-VIS, FT-IR-ATR, DLS, potencial zeta, MEV e EDS e foram utilizadas para catalisar mais três acoplamentos de Suzuki com rendimentos de 74 por cento a 86 por cento. Um suporte lignocelulósico, mecanicamente e termicamente resistente, feito a partir da biomassa de bambu foi funcionalizado com 1-oxil-2,2,6,6-tetrametilpiperidina (TEMPO) e caracterizado por FT-IR-ATR. Foi, então, impregnado para a imobilização de Na2PdCl4 (T_PdCl2) e das Nps Pd reduzidas e estabilizadas com CMC escolhidas (T_PdCMC_R). Os catalisadores desenvolvidos foram caracterizados por FT-IR-ATR, MEV e EDS. O catalisador T_PdCl2 foi utilizado em 4 reações seguidas com perdas de rendimento a cada reação (de 92,2 por cento até 18,4 por cento). Por ICP OES foi determinado que a quantidade de paládio lixiviada foi de 0,20 ppm na primeira reação e de 0,10 ppm nas reações seguintes. O catalisador T_PdCMC_R foi usado para a reação acoplamento entre ácido fenilborônico e 4-iodofenol e, em diferentes condições, obteve rendimentos de 35 por cento e 43 por cento.

[en] Suzuki C-C coupling reaction, since its discovery, has always attracted the interest of researchers and has found application in several fields both in academia and industry. Driven by environmental problems that concern our society so…

Advisors/Committee Members: OMAR GINOBLE PANDOLI.

Subjects/Keywords: [pt] BAMBU; [pt] REACAO DE SUZUKI; [pt] NANOPARTICULAS DE PALADIO; [pt] CATALISE HETEROGENEA; [en] BAMBOO; [en] SUZUKI REACTION; [en] PALLADIUM NANOPARTICLES; [en] HETEROGENEOUS CATALYSIS

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

author], [. (2021). [en] BAMBOO LIGNOCELLULOSIC SUPPORT IMPREGNATED WITH PALLADIUM AND ITS APPLICATION FOR SUZUKI REACTION. (Thesis). Pontifical Catholic University of Rio de Janeiro. Retrieved from http://www.maxwell.vrac.puc-rio.br/Busca_etds.php?strSecao=resultado&nrSeq=51181

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

author], [No. “[en] BAMBOO LIGNOCELLULOSIC SUPPORT IMPREGNATED WITH PALLADIUM AND ITS APPLICATION FOR SUZUKI REACTION.” 2021. Thesis, Pontifical Catholic University of Rio de Janeiro. Accessed March 07, 2021. http://www.maxwell.vrac.puc-rio.br/Busca_etds.php?strSecao=resultado&nrSeq=51181.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

author], [No. “[en] BAMBOO LIGNOCELLULOSIC SUPPORT IMPREGNATED WITH PALLADIUM AND ITS APPLICATION FOR SUZUKI REACTION.” 2021. Web. 07 Mar 2021.

Vancouver:

author] [. [en] BAMBOO LIGNOCELLULOSIC SUPPORT IMPREGNATED WITH PALLADIUM AND ITS APPLICATION FOR SUZUKI REACTION. [Internet] [Thesis]. Pontifical Catholic University of Rio de Janeiro; 2021. [cited 2021 Mar 07]. Available from: http://www.maxwell.vrac.puc-rio.br/Busca_etds.php?strSecao=resultado&nrSeq=51181.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

author] [. [en] BAMBOO LIGNOCELLULOSIC SUPPORT IMPREGNATED WITH PALLADIUM AND ITS APPLICATION FOR SUZUKI REACTION. [Thesis]. Pontifical Catholic University of Rio de Janeiro; 2021. Available from: http://www.maxwell.vrac.puc-rio.br/Busca_etds.php?strSecao=resultado&nrSeq=51181

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

24. D'Attoma, Joseph. Conception, synthèses et évaluations biologiques d’inhibiteurs à double cible : ALK et la restriction calorique : Design, synthesis and biological evaluations of inhibitors double target : ALK and caloric restriction.

Degree: Docteur es, Chimie, 2013, Université Claude Bernard – Lyon I

URL: http://www.theses.fr/2013LYO10243

►

Les lymphomes à grandes cellules anaplasiques ou ALCL (Anaplastic Large-Cell Lymphoma) sont des cancers appartenant à la famille des lymphomes de type non-Hodgkin. La majorité… (more)

▼

Les lymphomes à grandes cellules anaplasiques ou ALCL (Anaplastic Large-Cell Lymphoma) sont des cancers appartenant à la famille des lymphomes de type non-Hodgkin. La majorité des ALCL est issue d'une translocation t(2;5)(p23;q35) donnant lieu à la formation d'une protéine de fusion appelée NPM-ALK. A ce jour, peu d'inhibiteurs présentent de bonnes activités contre cette protéine chimérique. L'obésité représente un problème socio-médical d'envergure, à la fois pour ses effets directs et indirects ; le surpoids étant un facteur primaire dans de nombreuses maladies, tout particulièrement les diabètes, les accidents cardiovasculaires, le cancer, etc. A contrario, une restriction calorique (RC) est associée à des bénéfices importants en terme de santé. A l'issue de plusieurs criblages, un inhibiteur au motif 2-acylaminothiazole a montré une activité anticancéreuse sur ALK mais également la faculté de mimer la restriction calorique chez C. Elegans. Par conséquent, les travaux de recherche réalisés lors de cette thèse ont concerné la synthèse d'inhibiteurs comportant le squelette 2-acylaminothiazole. Les chromatographies d'affinité effectuées sur deux de nos inhibiteurs ont permis l'identification de cibles principales potentielles dans le cadre de la restriction calorique et des cibles secondaires possibles pour NPM-ALK. Ensuite, la présence d'un atome de brome sur le cycle aromatique a mené à la formation de liaisons C(sp2)-C(sp2), C(sp2)-C(sp) et C(sp2)- N, en utilisant les couplages catalysés par le palladium. Les différentes méthodes de modulation chimique ont conduit à mettre en place une librairie de 134 molécules. Certains d'entres eux et plus précisément ceux possédant un atome de silicium ont démontré une très bonne activité contre ALK et son mutant L1196M. Enfin, des résultats préliminaires ont également été obtenus sur le sujet de la restriction calorique avec quatre composés montrant une réduction du taux de lipides chez C. Elegans

Anaplastic Large-Cell Lymphoma (ALCL) is a type of cancer belonging to the non-Hodgkin family. The majority of ALCL arises from a translocation t(2;5) (p23;35) which leads to the formation of a fusion protein called NPM-ALK. Nowadays, few molecules are known to inhibit the activity of this chimeric protein. Obesity is a major socio-medical problem, for both direct and indirect effects, overweight is a primary factor in many diseases, especially diabetes, cardiovascular events, cancer, etc... In contrast, caloric restriction (CR) is associated with significant benefits in terms of health. After several screenings, one inhibitor based on a 2-acylaminothiazol scaffold showed anticancer activity on the protein ALK but also the ability to mimic caloric restriction in C. Elegans. The aim of this PhD was to develop the synthesis of new inhibitors including the 2-acylaminothiazol scaffold. The affinity chromatography performed on two of our inhibitors was used to identify potential major cellular targets in the process of caloric restriction and secondary cellular targets for NPM-ALK.…

Advisors/Committee Members: Goekjian, Peter (thesis director).

Subjects/Keywords: 2-acylaminothiazoles; Restriction calorique; ALCL; NPM-ALK; Réaction de Suzuki- Miyaura; Réaction de Buchwald-Hartwig; Réaction de Sonogashira; 2-acylaminothiazols; Caloric restriction; ALCL; NPM-ALK; Suzuki-Miyaura crosscoupling reaction; Buchwald-Hartwig cross-coupling reaction; Sonogashira cross-coupling reaction; 547

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

D'Attoma, J. (2013). Conception, synthèses et évaluations biologiques d’inhibiteurs à double cible : ALK et la restriction calorique : Design, synthesis and biological evaluations of inhibitors double target : ALK and caloric restriction. (Doctoral Dissertation). Université Claude Bernard – Lyon I. Retrieved from http://www.theses.fr/2013LYO10243

Chicago Manual of Style (16^th Edition):

D'Attoma, Joseph. “Conception, synthèses et évaluations biologiques d’inhibiteurs à double cible : ALK et la restriction calorique : Design, synthesis and biological evaluations of inhibitors double target : ALK and caloric restriction.” 2013. Doctoral Dissertation, Université Claude Bernard – Lyon I. Accessed March 07, 2021. http://www.theses.fr/2013LYO10243.

MLA Handbook (7^th Edition):

D'Attoma, Joseph. “Conception, synthèses et évaluations biologiques d’inhibiteurs à double cible : ALK et la restriction calorique : Design, synthesis and biological evaluations of inhibitors double target : ALK and caloric restriction.” 2013. Web. 07 Mar 2021.

Vancouver:

D'Attoma J. Conception, synthèses et évaluations biologiques d’inhibiteurs à double cible : ALK et la restriction calorique : Design, synthesis and biological evaluations of inhibitors double target : ALK and caloric restriction. [Internet] [Doctoral dissertation]. Université Claude Bernard – Lyon I; 2013. [cited 2021 Mar 07]. Available from: http://www.theses.fr/2013LYO10243.

Council of Science Editors:

D'Attoma J. Conception, synthèses et évaluations biologiques d’inhibiteurs à double cible : ALK et la restriction calorique : Design, synthesis and biological evaluations of inhibitors double target : ALK and caloric restriction. [Doctoral Dissertation]. Université Claude Bernard – Lyon I; 2013. Available from: http://www.theses.fr/2013LYO10243

NSYSU

25. Li, Yi-wei. Aggregation-Induced Emission Enhancement of organic and polymeric fluorophores containing 2,4,6-Triphenylpyridine moiety.

Degree: Master, Materials and Optoelectronic Science, 2012, NSYSU

URL: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0713112-173820

► In this study, organic and polymeric fluorophores based on 2,4,6-triphenylpyridiene (TPP) structure were found to have the novel aggregation-induced emission enhancement (AIEE) property. For the… (more)

Subjects/Keywords: 6-triphenylpyridiene; 4; quantum yield (ФF); suzuki coupling; 2; Chichibabin reaction; aggregation-induced emission enhancement (AIEE); crystallization-induced emission enhancement (CIEE)

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Li, Y. (2012). Aggregation-Induced Emission Enhancement of organic and polymeric fluorophores containing 2,4,6-Triphenylpyridine moiety. (Thesis). NSYSU. Retrieved from http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0713112-173820

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Li, Yi-wei. “Aggregation-Induced Emission Enhancement of organic and polymeric fluorophores containing 2,4,6-Triphenylpyridine moiety.” 2012. Thesis, NSYSU. Accessed March 07, 2021. http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0713112-173820.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Li, Yi-wei. “Aggregation-Induced Emission Enhancement of organic and polymeric fluorophores containing 2,4,6-Triphenylpyridine moiety.” 2012. Web. 07 Mar 2021.

Vancouver:

Li Y. Aggregation-Induced Emission Enhancement of organic and polymeric fluorophores containing 2,4,6-Triphenylpyridine moiety. [Internet] [Thesis]. NSYSU; 2012. [cited 2021 Mar 07]. Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0713112-173820.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Li Y. Aggregation-Induced Emission Enhancement of organic and polymeric fluorophores containing 2,4,6-Triphenylpyridine moiety. [Thesis]. NSYSU; 2012. Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0713112-173820

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

26. 贾, 吉祥. Development of highly effective reaction system using supported Pd catalysts for the Suzuki-Miyaura coupling of bromobenzene and chlorobenzene with phenylboronic acid.

Degree: Japan Advanced Institute of Science and Technology / 北陸先端科学技術大学院大学

URL: http://hdl.handle.net/10119/11940

Supervisor:海老谷幸喜

マテリアルサイエンス研究科

修士

Subjects/Keywords: Suzuki-Miyaura coupling reaction; Palladium; Hydrotalcite; Mgnesium hydroxide; Surfactant

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APA (6^th Edition):

贾, �. (n.d.). Development of highly effective reaction system using supported Pd catalysts for the Suzuki-Miyaura coupling of bromobenzene and chlorobenzene with phenylboronic acid. (Thesis). Japan Advanced Institute of Science and Technology / 北陸先端科学技術大学院大学. Retrieved from http://hdl.handle.net/10119/11940

Note: this citation may be lacking information needed for this citation format:
No year of publication.
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

贾, 吉祥. “Development of highly effective reaction system using supported Pd catalysts for the Suzuki-Miyaura coupling of bromobenzene and chlorobenzene with phenylboronic acid.” Thesis, Japan Advanced Institute of Science and Technology / 北陸先端科学技術大学院大学. Accessed March 07, 2021. http://hdl.handle.net/10119/11940.

Note: this citation may be lacking information needed for this citation format:
No year of publication.
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

贾, 吉祥. “Development of highly effective reaction system using supported Pd catalysts for the Suzuki-Miyaura coupling of bromobenzene and chlorobenzene with phenylboronic acid.” Web. 07 Mar 2021.

Note: this citation may be lacking information needed for this citation format:
No year of publication.

Vancouver:

贾 �. Development of highly effective reaction system using supported Pd catalysts for the Suzuki-Miyaura coupling of bromobenzene and chlorobenzene with phenylboronic acid. [Internet] [Thesis]. Japan Advanced Institute of Science and Technology / 北陸先端科学技術大学院大学; [cited 2021 Mar 07]. Available from: http://hdl.handle.net/10119/11940.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
No year of publication.

Council of Science Editors:

贾 �. Development of highly effective reaction system using supported Pd catalysts for the Suzuki-Miyaura coupling of bromobenzene and chlorobenzene with phenylboronic acid. [Thesis]. Japan Advanced Institute of Science and Technology / 北陸先端科学技術大学院大学; Available from: http://hdl.handle.net/10119/11940

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
No year of publication.

University of the Western Cape

27. Ramoroka, Morongwa Emmanuel. Photophysics of Thiophenosalicylaldimine-functionalized G1-Polyprolyleniminato-Copper Telluride/Antimonide core-shell Nanomaterials .

Degree: 2018, University of the Western Cape

URL: http://hdl.handle.net/11394/6262

► This work involves the synthesis of copper telluride-polypropylenimine tetra(5-(2-thienyl) salicylaldimine) ([email protected]) and copper antimonide-polypropylenimine tetra(5-(2-thienyl) salicylaldimine) ([email protected]) core-shell nanoparticles (NPs), using two-pots and one-pot synthesis… (more)

▼ This work involves the synthesis of copper telluride-polypropylenimine tetra(5-(2-thienyl) salicylaldimine) ([email protected]) and copper antimonide-polypropylenimine tetra(5-(2-thienyl) salicylaldimine) ([email protected]) core-shell nanoparticles (NPs), using two-pots and one-pot synthesis methods, respectively. Their morphology was studied by X-ray diffraction spectroscopy (XRD), high resolution transmission electron microscopy (HRTEM) and high resolution scanning electron microscopy (HRSEM); while their structures were characterized by Fourier transform infrared spectroscopy (FTIR) and elemental analysis. Photophysical properties of the core-shell NPs were determined from ultraviolet-visible absorption spectroscopy (UV-Vis) and photoluminescence spectroscopy (PL). For core-shell NPs produced via two-pots method only [email protected] exhibited ? ? ?* and n ? ?* which indicate that [email protected] produced via two-pots method was unsuccessfully synthesized. The ? ? ?* and n ? ?* transitions indicate the presence of polypropylenimine tetra(5-(2-thienyl) salicylaldimine) (PPI) on the surface of CuTe NPs and CuSb NPs. FTIR confirmed coordination of PPI on the surface of CuTe NPs and CuSb NPs by showing a shift in wavenumber of C=N group bands from PPI. HR-TEM showed that the [email protected] synthesized via one-pot method have a wide particles sizes distribution with an average particles size of 13.60 nm while for [email protected] synthesized via two-pots it was impossible to determine the particles size due to aggregation. [email protected] synthesized via twopots method and one-pot method has a wide particles sizes distribution with an average size of 7.98 nm and 11.61 nm respectively. The average particles sizes determined by HR-SEM were found to be 35.24 nm ([email protected] two-pots method), 33.90 nm ([email protected] one-pot method), 18.30 nm ([email protected] two-pots method), and 16.18 nm ([email protected] one pot method). Advisors/Committee Members: Iwuoha, Emmanuel I (advisor).

Subjects/Keywords: Bimetallic nanoparticles; Metal-chalcogenides nanoparticles; Dendrimers; Core-shell nanoparticles; Photophysics; Photovoltaics; Electrochemical characterization; Schiff base condensation; Chemical reduction; Suzuki coupling reaction

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APA (6^th Edition):

Ramoroka, M. E. (2018). Photophysics of Thiophenosalicylaldimine-functionalized G1-Polyprolyleniminato-Copper Telluride/Antimonide core-shell Nanomaterials . (Thesis). University of the Western Cape. Retrieved from http://hdl.handle.net/11394/6262

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Ramoroka, Morongwa Emmanuel. “Photophysics of Thiophenosalicylaldimine-functionalized G1-Polyprolyleniminato-Copper Telluride/Antimonide core-shell Nanomaterials .” 2018. Thesis, University of the Western Cape. Accessed March 07, 2021. http://hdl.handle.net/11394/6262.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Ramoroka, Morongwa Emmanuel. “Photophysics of Thiophenosalicylaldimine-functionalized G1-Polyprolyleniminato-Copper Telluride/Antimonide core-shell Nanomaterials .” 2018. Web. 07 Mar 2021.

Vancouver:

Ramoroka ME. Photophysics of Thiophenosalicylaldimine-functionalized G1-Polyprolyleniminato-Copper Telluride/Antimonide core-shell Nanomaterials . [Internet] [Thesis]. University of the Western Cape; 2018. [cited 2021 Mar 07]. Available from: http://hdl.handle.net/11394/6262.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Ramoroka ME. Photophysics of Thiophenosalicylaldimine-functionalized G1-Polyprolyleniminato-Copper Telluride/Antimonide core-shell Nanomaterials . [Thesis]. University of the Western Cape; 2018. Available from: http://hdl.handle.net/11394/6262

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

28. Abou Hamdan, Hussein. Synthèse de nouveaux agents anticancéreux : Synthesis of new anticancer agents.

Degree: Docteur es, Chimie, 2018, Université de Strasbourg

URL: http://www.theses.fr/2018STRAF012

►

Les cancers représentent un problème majeur de santé public d'où la nécessité de rechercher de nouvelles classes de médicaments. Parmi les pistes pour développer de… (more)

▼

Les cancers représentent un problème majeur de santé public d'où la nécessité de rechercher de nouvelles classes de médicaments. Parmi les pistes pour développer de nouveaux traitements, deux ont retenu notre attention et celle de nos collaborateurs : la modulation de l’épissage par des composés comme le NVS-SM2, et l’inhibition de l’oncogène KRAS par des dérivés de produits naturels, les flavaglines. Dans ce contexte, nous avons développé la première synthèse robuste du NVS-SM2, qui peut satisfaire la demande globale de cet agent pour examiner en détail son potentiel thérapeutique dans différents types d’affection. En outre, la stratégie de synthèse rapportée ici pourrait être étendue à de nouveaux analogues de ce composé. D’autre part, nous avons synthétisé de nouvelles flavaglines qui sont en cours d'étude pour leurs effets sur l’inhibition de KRAS. Au cours de cette étude, nous avons découvert de nouvelles réactions, notamment une inversion de configuration d’amines induite par du chlorure de diméthylcarbamoyle.

Cancers represent a major public health problem hence the need to use new classes of medicines. Among the opportunities for developing new treatments, two have caught our attention and that of our collaborators: the modulation of splicing by compounds such as NVS-SM2, and the inhibition of the oncogene KRAS by derivatives of natural products, the flavaglines.In this context, we have developed the first robust synthesis of NVS-SM2, which can satisfy the global demand of this agent to examine in detail its therapeutic potential in different types of disorders. In addition, the synthetic strategy reported here could be extended to new analogues of this compound. Furthermore, we have synthesized new flavaglines that have been examined for their effects on KRAS inhibition. During this study, we discovered new reactions, including a dimethylcarbamoyl chloride-induced amine inversion of configuration.

Advisors/Committee Members: Désaubry, Laurent (thesis director).

Subjects/Keywords: Modulateurs d'épissage; NVS-SM2; Pyridazine; Flavagline; Chimie hétérocyclique; Splicing modulators; NVS-SM2; Pyridazine; Suzuki-Miyaura reaction; Flavaglines; KRAS; Heterocyclic chemistry

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Abou Hamdan, H. (2018). Synthèse de nouveaux agents anticancéreux : Synthesis of new anticancer agents. (Doctoral Dissertation). Université de Strasbourg. Retrieved from http://www.theses.fr/2018STRAF012

Chicago Manual of Style (16^th Edition):

Abou Hamdan, Hussein. “Synthèse de nouveaux agents anticancéreux : Synthesis of new anticancer agents.” 2018. Doctoral Dissertation, Université de Strasbourg. Accessed March 07, 2021. http://www.theses.fr/2018STRAF012.

MLA Handbook (7^th Edition):

Abou Hamdan, Hussein. “Synthèse de nouveaux agents anticancéreux : Synthesis of new anticancer agents.” 2018. Web. 07 Mar 2021.

Vancouver:

Abou Hamdan H. Synthèse de nouveaux agents anticancéreux : Synthesis of new anticancer agents. [Internet] [Doctoral dissertation]. Université de Strasbourg; 2018. [cited 2021 Mar 07]. Available from: http://www.theses.fr/2018STRAF012.

Council of Science Editors:

Abou Hamdan H. Synthèse de nouveaux agents anticancéreux : Synthesis of new anticancer agents. [Doctoral Dissertation]. Université de Strasbourg; 2018. Available from: http://www.theses.fr/2018STRAF012

Universitat de Girona

29. Ng Choi, I-teng Montserrat. Solid-phase synthesis of 5-arylhistidine-containing peptides: from linear antimicrobial peptides to cyclic peptides derived from arylomycins and aciculitins.

Degree: Departament de Química, 2015, Universitat de Girona

URL: http://hdl.handle.net/10803/380739

► La incorporació de sistemes biarílics asimiètrics en seqüències peptídiques es considera un enfocament útil per a millorar l'activitat biològica de pèptids. Tenint en compte la… (more)

Subjects/Keywords: Histidine; Histidina; Biaryl peptides; Pèptids biarílics; Péptidos biarílicos; Microwave irradiation; Irradiació de microones; Irradiación de microondas; Macroarylation; Macroarilació; Macroarilación; Arylomycins; Arilomicines; Arilomicinas; Suzuki-Miyaura reaction; Reacción Suzuki-Miyaura; Reacció Suzuki-Miyaura; 547

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APA (6^th Edition):

Ng Choi, I. M. (2015). Solid-phase synthesis of 5-arylhistidine-containing peptides: from linear antimicrobial peptides to cyclic peptides derived from arylomycins and aciculitins. (Thesis). Universitat de Girona. Retrieved from http://hdl.handle.net/10803/380739

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Ng Choi, I-teng Montserrat. “Solid-phase synthesis of 5-arylhistidine-containing peptides: from linear antimicrobial peptides to cyclic peptides derived from arylomycins and aciculitins.” 2015. Thesis, Universitat de Girona. Accessed March 07, 2021. http://hdl.handle.net/10803/380739.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Ng Choi, I-teng Montserrat. “Solid-phase synthesis of 5-arylhistidine-containing peptides: from linear antimicrobial peptides to cyclic peptides derived from arylomycins and aciculitins.” 2015. Web. 07 Mar 2021.

Vancouver:

Ng Choi IM. Solid-phase synthesis of 5-arylhistidine-containing peptides: from linear antimicrobial peptides to cyclic peptides derived from arylomycins and aciculitins. [Internet] [Thesis]. Universitat de Girona; 2015. [cited 2021 Mar 07]. Available from: http://hdl.handle.net/10803/380739.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Ng Choi IM. Solid-phase synthesis of 5-arylhistidine-containing peptides: from linear antimicrobial peptides to cyclic peptides derived from arylomycins and aciculitins. [Thesis]. Universitat de Girona; 2015. Available from: http://hdl.handle.net/10803/380739

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universitat de Girona

30. Afonso Afonso, Ana. Pèptids biarílics a partir de 4-iodofenilalanina o 3-iodotirosina per borilació i reacció de Suzuki-Miyaura en fase sòlida. Avaluació de l'activitat antimicrobiana.

Degree: Departament de Química, 2011, Universitat de Girona

URL: http://hdl.handle.net/10803/38882

► The present PhD study was focused on the preparation of biaryl peptides on solid-phase. First, phenylalanine or tyrosine residues were borylated through a Miyaura reaction.… (more)

Subjects/Keywords: Pèptids biarílics; Biaryl peptides; Péptidos biarílicos; Pèptids antimicrobials; Antimicrobial peptides; Péptidos antimicrobianos; Irradiació de microones; Microwave irradiation; Irradiación de microondas; Fase sòlida; Solid-phase; Fase sólida; Borilació; Borilation; Borilación; Reacció de Suzuki-Miyaura; Suzuki-Miyaura reaction; Reacción de Suzuki-Miyaura; 547

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Afonso Afonso, A. (2011). Pèptids biarílics a partir de 4-iodofenilalanina o 3-iodotirosina per borilació i reacció de Suzuki-Miyaura en fase sòlida. Avaluació de l'activitat antimicrobiana. (Thesis). Universitat de Girona. Retrieved from http://hdl.handle.net/10803/38882

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Afonso Afonso, Ana. “Pèptids biarílics a partir de 4-iodofenilalanina o 3-iodotirosina per borilació i reacció de Suzuki-Miyaura en fase sòlida. Avaluació de l'activitat antimicrobiana.” 2011. Thesis, Universitat de Girona. Accessed March 07, 2021. http://hdl.handle.net/10803/38882.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Afonso Afonso, Ana. “Pèptids biarílics a partir de 4-iodofenilalanina o 3-iodotirosina per borilació i reacció de Suzuki-Miyaura en fase sòlida. Avaluació de l'activitat antimicrobiana.” 2011. Web. 07 Mar 2021.

Vancouver:

Afonso Afonso A. Pèptids biarílics a partir de 4-iodofenilalanina o 3-iodotirosina per borilació i reacció de Suzuki-Miyaura en fase sòlida. Avaluació de l'activitat antimicrobiana. [Internet] [Thesis]. Universitat de Girona; 2011. [cited 2021 Mar 07]. Available from: http://hdl.handle.net/10803/38882.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Afonso Afonso A. Pèptids biarílics a partir de 4-iodofenilalanina o 3-iodotirosina per borilació i reacció de Suzuki-Miyaura en fase sòlida. Avaluació de l'activitat antimicrobiana. [Thesis]. Universitat de Girona; 2011. Available from: http://hdl.handle.net/10803/38882

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Open Access Theses and Dissertations