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Stellenbosch University

1. Imran, Syed Ali. The reasons for changing HAART in HIV positive patients at the Thusong comprehensive care management and treatment site, West Rand district, Johannesburg, Gauteng.

Degree: MMed, Interdisciplinary Health Sciences, 2011, Stellenbosch University

Objective To determine the reasons for the change or modification in the first line HAART regimen (1a and 1b) in HIV positive patients at the Thusong CCMT site. Methods This study is a quantitative descriptive study using a standardized data collection tool to extract retrospective data from medical records. Subjects Subjects for this study included patients 18 years or older attending the Thusong CCMT site, which were started on HAART regimens 1a or 1b and were on treatment for at least 6 months. The final sample size evaluated was 257 patients. Results There was a high rate (43%) of change or modification of the first line HAART regimen. Majority of the patient’s (72%) had their regimen modified due to side effects of the drugs and only a small number (9.7%) of patients had a complete change in the regimen due to virological failure. Stavudine (d4T) associated lipodystrophy was the most common side effect (45.5%) followed by peripheral neuropathy (16.7%), leading to treatment modification. Conclusion The rate of modification or change of first line HAART regimen, at Thusong CCMT, was fairly high (42.6%), and the most common reason for the modification or change was drug side effect of stavudine (d4T). Advisors/Committee Members: Gunst, Colette, Stellenbosch University. Faculty of Health Sciences. Dept. of Interdisciplinary Health Sciences..

Subjects/Keywords: HIV positive persons  – Treatment; Highly active antiretroviral therapy (HAART); Stavudine  – Side effects; UCTD; UCTD

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Imran, S. A. (2011). The reasons for changing HAART in HIV positive patients at the Thusong comprehensive care management and treatment site, West Rand district, Johannesburg, Gauteng. (Thesis). Stellenbosch University. Retrieved from http://hdl.handle.net/10019.1/97249

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Imran, Syed Ali. “The reasons for changing HAART in HIV positive patients at the Thusong comprehensive care management and treatment site, West Rand district, Johannesburg, Gauteng.” 2011. Thesis, Stellenbosch University. Accessed April 11, 2021. http://hdl.handle.net/10019.1/97249.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Imran, Syed Ali. “The reasons for changing HAART in HIV positive patients at the Thusong comprehensive care management and treatment site, West Rand district, Johannesburg, Gauteng.” 2011. Web. 11 Apr 2021.

Vancouver:

Imran SA. The reasons for changing HAART in HIV positive patients at the Thusong comprehensive care management and treatment site, West Rand district, Johannesburg, Gauteng. [Internet] [Thesis]. Stellenbosch University; 2011. [cited 2021 Apr 11]. Available from: http://hdl.handle.net/10019.1/97249.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Imran SA. The reasons for changing HAART in HIV positive patients at the Thusong comprehensive care management and treatment site, West Rand district, Johannesburg, Gauteng. [Thesis]. Stellenbosch University; 2011. Available from: http://hdl.handle.net/10019.1/97249

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

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