subject:(Spectroscopy by nuclear magnetic resonance)

University of Alberta

1. Dwan, Jerrod Ryan. Investigating the 197Au-31P spin-spin coupling interactions in gold-phosphine halides using solid-state nuclear magnetic resonance, spectral simulations, and quantum chemistry computations.

Degree: MS, Department of Chemistry, 2011, University of Alberta

URL: https://era.library.ualberta.ca/files/tm70mw653

► Phosphorus-31 nuclear magnetic resonance spectroscopy with magic angle spinning was used to characterize 197Au-31P spin-spin coupling interactions in solid gold-phosphine halides and the spectra have… (more)

Subjects/Keywords: Nuclear magnetic resonance spectroscopy; Nuclear magnetic resonance

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Dwan, J. R. (2011). Investigating the 197Au-31P spin-spin coupling interactions in gold-phosphine halides using solid-state nuclear magnetic resonance, spectral simulations, and quantum chemistry computations. (Masters Thesis). University of Alberta. Retrieved from https://era.library.ualberta.ca/files/tm70mw653

Chicago Manual of Style (16^th Edition):

Dwan, Jerrod Ryan. “Investigating the 197Au-31P spin-spin coupling interactions in gold-phosphine halides using solid-state nuclear magnetic resonance, spectral simulations, and quantum chemistry computations.” 2011. Masters Thesis, University of Alberta. Accessed March 03, 2021. https://era.library.ualberta.ca/files/tm70mw653.

MLA Handbook (7^th Edition):

Dwan, Jerrod Ryan. “Investigating the 197Au-31P spin-spin coupling interactions in gold-phosphine halides using solid-state nuclear magnetic resonance, spectral simulations, and quantum chemistry computations.” 2011. Web. 03 Mar 2021.

Vancouver:

Dwan JR. Investigating the 197Au-31P spin-spin coupling interactions in gold-phosphine halides using solid-state nuclear magnetic resonance, spectral simulations, and quantum chemistry computations. [Internet] [Masters thesis]. University of Alberta; 2011. [cited 2021 Mar 03]. Available from: https://era.library.ualberta.ca/files/tm70mw653.

Council of Science Editors:

Dwan JR. Investigating the 197Au-31P spin-spin coupling interactions in gold-phosphine halides using solid-state nuclear magnetic resonance, spectral simulations, and quantum chemistry computations. [Masters Thesis]. University of Alberta; 2011. Available from: https://era.library.ualberta.ca/files/tm70mw653

2. Palaychuk, Natalie. Towards Automated NMR Assignments via Optimization with Sparse NOE and Backbone Correlation Data.

Degree: Department of Molecular Pharmacology, Physiology and Biotechnology, 2018, Brown University

URL: https://repository.library.brown.edu/studio/item/bdr:792855/

► NMR Spectroscopy is widely used in molecular structural determination. For small molecules it enables simple atomic assignments, and recent advances in the field have enabled… (more)

Subjects/Keywords: Nuclear magnetic resonance spectroscopy

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Palaychuk, N. (2018). Towards Automated NMR Assignments via Optimization with Sparse NOE and Backbone Correlation Data. (Thesis). Brown University. Retrieved from https://repository.library.brown.edu/studio/item/bdr:792855/

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Palaychuk, Natalie. “Towards Automated NMR Assignments via Optimization with Sparse NOE and Backbone Correlation Data.” 2018. Thesis, Brown University. Accessed March 03, 2021. https://repository.library.brown.edu/studio/item/bdr:792855/.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Palaychuk, Natalie. “Towards Automated NMR Assignments via Optimization with Sparse NOE and Backbone Correlation Data.” 2018. Web. 03 Mar 2021.

Vancouver:

Palaychuk N. Towards Automated NMR Assignments via Optimization with Sparse NOE and Backbone Correlation Data. [Internet] [Thesis]. Brown University; 2018. [cited 2021 Mar 03]. Available from: https://repository.library.brown.edu/studio/item/bdr:792855/.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Palaychuk N. Towards Automated NMR Assignments via Optimization with Sparse NOE and Backbone Correlation Data. [Thesis]. Brown University; 2018. Available from: https://repository.library.brown.edu/studio/item/bdr:792855/

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Hong Kong University of Science and Technology

3. Ren, Yaguang SENG. Super-resolution spectral reconstruction for fast nuclear magnetic resonance (NMR) spectroscopy with non-uniform sampling schemes.

Degree: 2018, Hong Kong University of Science and Technology

URL: http://repository.ust.hk/ir/Record/1783.1-95386 ; https://doi.org/10.14711/thesis-991012634968303412 ; http://repository.ust.hk/ir/bitstream/1783.1-95386/1/th_redirect.html

► High-throughput Nuclear Magnetic Resonance (NMR) spectroscopy, as well as structural determination of biomolecules and characterization of short-lived molecular systems by multi-dimensional NMR spectroscopy require to… (more)

▼ High-throughput Nuclear Magnetic Resonance (NMR) spectroscopy, as well as structural determination of biomolecules and characterization of short-lived molecular systems by multi-dimensional NMR spectroscopy require to shorten the data measurement time, meanwhile to achieve higher resolution and sensitivity NMR spectra. Currently proposed Non-uniform Sampling (NUS) scheme provides an ingenious way to accomplish the abovementioned goals. In this thesis work, I analyzed and modified two NUS spectral reconstruction schemes and demonstrated they are more robust than the previously described methods. At first, high-resolution NMR spectral reconstruction method, constrained Hankel nuclear norm minimization algorithm (CHARM), is proposed, which outperforms the Hankel nuclear norm minimization algorithm (HARM) method showing higher resolution and sensitivity. Secondly, super-resolution NMR spectral reconstruction method named zero constrained Toeplitz minimization (zc-TOP) is put forward, in which through minimizing the trace of a Toeplitz matrix formed by the NUS data set to recover the unrecorded data points computationally. In addition, the decay function is extracted by fitting to the limited number of NUS data points. After applying the decay function into the minimization and deconvolution procedures, the non-decayed free induction data (FID) is used to reconstruct a super-resolution NMR spectrum. Moreover, the NUS sampling scheme is also analyzed as different sampling schemes will result in different reconstruction spectra. According to our results, the exponential sampling scheme among the first half of the FID for decay signals and among the whole FID for non-decay signals show better spectral reconstruction results for our proposed methods. To achieve higher resolution NMR spectra by post-processing solvent suppression scheme, a singular value decomposition (SVD) based solvent suppression algorithm is developed to extract the useful information buried by the extremely strong solvent signal. The FID is decomposed first and then singular values represent the solvent information are set to zeros. Consequently, the undesired solvent signal is removed. With the above methods, we were able to obtain NMR spectra with high resolution, sensitivity and less experimental time. We believed that these methods could be widely used in the NMR community.

Subjects/Keywords: Nuclear magnetic resonance spectroscopy ; Nuclear magnetic resonance ; Molecular probes

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Ren, Y. S. (2018). Super-resolution spectral reconstruction for fast nuclear magnetic resonance (NMR) spectroscopy with non-uniform sampling schemes. (Thesis). Hong Kong University of Science and Technology. Retrieved from http://repository.ust.hk/ir/Record/1783.1-95386 ; https://doi.org/10.14711/thesis-991012634968303412 ; http://repository.ust.hk/ir/bitstream/1783.1-95386/1/th_redirect.html

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Ren, Yaguang SENG. “Super-resolution spectral reconstruction for fast nuclear magnetic resonance (NMR) spectroscopy with non-uniform sampling schemes.” 2018. Thesis, Hong Kong University of Science and Technology. Accessed March 03, 2021. http://repository.ust.hk/ir/Record/1783.1-95386 ; https://doi.org/10.14711/thesis-991012634968303412 ; http://repository.ust.hk/ir/bitstream/1783.1-95386/1/th_redirect.html.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Ren, Yaguang SENG. “Super-resolution spectral reconstruction for fast nuclear magnetic resonance (NMR) spectroscopy with non-uniform sampling schemes.” 2018. Web. 03 Mar 2021.

Vancouver:

Ren YS. Super-resolution spectral reconstruction for fast nuclear magnetic resonance (NMR) spectroscopy with non-uniform sampling schemes. [Internet] [Thesis]. Hong Kong University of Science and Technology; 2018. [cited 2021 Mar 03]. Available from: http://repository.ust.hk/ir/Record/1783.1-95386 ; https://doi.org/10.14711/thesis-991012634968303412 ; http://repository.ust.hk/ir/bitstream/1783.1-95386/1/th_redirect.html.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Ren YS. Super-resolution spectral reconstruction for fast nuclear magnetic resonance (NMR) spectroscopy with non-uniform sampling schemes. [Thesis]. Hong Kong University of Science and Technology; 2018. Available from: http://repository.ust.hk/ir/Record/1783.1-95386 ; https://doi.org/10.14711/thesis-991012634968303412 ; http://repository.ust.hk/ir/bitstream/1783.1-95386/1/th_redirect.html

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Stellenbosch University

4. Heyns, Ingrid Marie. Synthesis and structure-property relationships of 3-methylene-2-pyrrolidone-based (co)polymers.

Degree: MSc, Chemistry and Polymer Science, 2015, Stellenbosch University

URL: http://hdl.handle.net/10019.1/96618

►

ENGLISH ABSTRACT: Recently, the incorporation of renewable resources as a substitute to fossil fuels in the synthesis of polymers/materials has attracted a vast amount of… (more)

▼

ENGLISH ABSTRACT: Recently, the incorporation of renewable resources as a substitute to fossil fuels in the synthesis of polymers/materials has attracted a vast amount of interest, particularly for the green advantages offered. This study describes the synthesis, polymerization and characterization of 3-methylene-2-pyrrolidone-based (3M2P) monomers, with 3M2P being a naturally occurring lactam moiety. Two different chemical syntheses of the monomer, 3M2P, were attempted, with the first approach involving the Wittig reaction for the formation of the exo-cyclic methylene group. The second approach involved the dehydration of 3-(hydroxymethyl)-2-pyrrolidone. Preference was given to the Wittig approach during the study conducted, as the dehydration reaction of the second approach was unsuccessful. The purification and control over by- and side-products of the Wittig approach were optimized and confirmed by various spectroscopic techniques. Statistical copolymerizations of 3M2P-based monomers revealed the formation of oligomers, while in situ 1H NMR spectroscopic experiments failed to quantify the incorporation or consumption of either monomers due to a peak overlap. Conventional radical homopolymerizations of 3M2P were successful and polymers were characterized by NMR spectroscopy and size exclusion chromatography (SEC). It was discovered that the polymer, P(3M2P), has very good thermal stability with a Tg = 285 °C and a decomposition temperature between 400-500 °C. P(3M2P) proved to be extremely water-soluble, but it did not dissolve in most organic solvents. The thermal and solubility behaviour were ascribed to the structurally rigid lactam moiety and its strong hydrogen-bonding ability. Cytotoxicity testing revealed that P(3M2P) was completely non-toxic. Finally, the polymerization versatility of 3M2P was evaluated via different living radical polymerization techniques in an attempt to create well-defined macromolecules with precision. SET-LRP and RAFT polymerizations proved to be controlled, with a Ð < 1.5, whilst NMP exhibited poor control. The RAFT polymerization was extended to an amphiphilic block copolymer with the first segment being polystyrene and the second segment, P(3M2P). During the chain-extension only oligomeric 3M2P species were incorporated.

AFRIKAANSE OPSOMMING: Met die toenemende belangstelling in die gebruik van meer omgewingsvriendelike materiale en die soeke na plaasvervangers vir nie-hernieubare fossielbrandstowwe vir die sintese van polimere, is daar ‘n alewige toename in die ontwikellinge van prosesse om die bogenoemde te bevorder. ‘n Benadering om die probleem te oorkom is om van hernubare hulpbronne gebruik te maak. Gevolglik fokus hierdie studie op die sintese, polimerisasie en ‘n ontleding van die karaktereienskappe van 3-metileen-2-pyrolidoon (3M2P) monomere. 3M2P is ‘n laktaam gedeelte wat natuurlik voorkom. Met die sintese van 3M2P, is twee verskillende chemiese benaderings aangepak. Voorkeur is gegee aan die benadering wat van die Wittig reaksie gebruik maak vir die vorming…

Advisors/Committee Members: Pfukwa, Rueben, Klumperman, Bert, Stellenbosch University. Faculty of Science. Dept. of Chemistry and Polymer Science..

Subjects/Keywords: Polymerization; UCTD; Nuclear magnetic resonance spectroscopy; Biopolymers

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Heyns, I. M. (2015). Synthesis and structure-property relationships of 3-methylene-2-pyrrolidone-based (co)polymers. (Masters Thesis). Stellenbosch University. Retrieved from http://hdl.handle.net/10019.1/96618

Chicago Manual of Style (16^th Edition):

Heyns, Ingrid Marie. “Synthesis and structure-property relationships of 3-methylene-2-pyrrolidone-based (co)polymers.” 2015. Masters Thesis, Stellenbosch University. Accessed March 03, 2021. http://hdl.handle.net/10019.1/96618.

MLA Handbook (7^th Edition):

Heyns, Ingrid Marie. “Synthesis and structure-property relationships of 3-methylene-2-pyrrolidone-based (co)polymers.” 2015. Web. 03 Mar 2021.

Vancouver:

Heyns IM. Synthesis and structure-property relationships of 3-methylene-2-pyrrolidone-based (co)polymers. [Internet] [Masters thesis]. Stellenbosch University; 2015. [cited 2021 Mar 03]. Available from: http://hdl.handle.net/10019.1/96618.

Council of Science Editors:

Heyns IM. Synthesis and structure-property relationships of 3-methylene-2-pyrrolidone-based (co)polymers. [Masters Thesis]. Stellenbosch University; 2015. Available from: http://hdl.handle.net/10019.1/96618

University of Missouri – Columbia

5. Xu, Jia (Research scientist). Stability, states, and interactions of the enzyme PMM/PGM by NMR and multivariate analysis: Stability, states, and interactions of the enzyme phosphomannomutase/phosphoglucomutase by nuclear magnetic resonance and multivariate analysis.

Degree: 2016, University of Missouri – Columbia

URL: https://doi.org/10.32469/10355/59793

► Phosphomannomutase/phosphoglucomutase (PMM/PGM) contributes to the infectivity of an opportunistic human pathogen Pseudomonas aeruginosa by participating in carbohydrate biosynthesis. As a phospho-transfer enzyme, PMM/PGM catalyzes reversible… (more)

▼ Phosphomannomutase/phosphoglucomutase (PMM/PGM) contributes to the infectivity of an opportunistic human pathogen Pseudomonas aeruginosa by participating in carbohydrate biosynthesis. As a phospho-transfer enzyme, PMM/PGM catalyzes reversible conversion between 1- and 6- phosphosugars via a bisphosphorylated hexose intermediate rotating 180[degree symbol] in the catalytic cleft. Although PMM/PGM is well studied both structurally and kinetically, the mechanisms of its intramolecular and intermolecular communication are less well understood, especially in solution. Multiple solution NMR techniques are used in this dissertation's work to reveal information on PMM/PGM interactions at the atomic level. NMR-detected hydrogen exchange in combination with molecular dynamics and electrostatic calculations found phosphorylation of active Ser108 residue stabilizes PMM/PGM by attracting domains together. Responses of PMM/PGM to various phosphosugars were characterized by NMR-detected titrations. The large set of assigned peaks were analyzed by various types of principal component analysis (PCA) to derive binding isotherms, over-arching relationships among phosphosugar ligand binding reactions, and equilibrium shifts of PMM/PGM during its catalytic cycle. PCA was also found to be able to extract binding isotherms directly from non-interpreted 2D NMR spectra of complexes forming in solution. Procedures were identified that are reliable for obtaining the binding isotherms, regardless of the spectral peaks being in the fast, slow, or intermediate exchange regimes, or mixtures thereof. Applying PCA to time-domain NMR data also yields binding isotherms from titrations in fast or slow exchange. The algorithm readily extracts from an MRI movie its time courses, such as breathing and heart rate in chest imaging. To enable the community to exploit these new capabilities, we have developed the multi-platform software named TREND to track equilibrium and non-equilibrium population shifts among 2D data frames. The principal components obtained represent the main changes among the data frames. Besides binding isotherms and time courses, the main changes extracted by TREND can be any variety of population shifts. TREND can reconstruct the series of measurements from selected principal components. TREND supports multiple data formats, including raw NMR data, images, movies, lists, and spreadsheet files. The software can also be used for data clustering or noise filtering. Advisors/Committee Members: Van Doren, Steven R., 1963- (advisor), Beamer, Lesa J. (Lesa Jean) (advisor).

Subjects/Keywords: Pseudomonas aeruginosa infections; Nuclear magnetic resonance spectroscopy

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Xu, J. (. s. (2016). Stability, states, and interactions of the enzyme PMM/PGM by NMR and multivariate analysis: Stability, states, and interactions of the enzyme phosphomannomutase/phosphoglucomutase by nuclear magnetic resonance and multivariate analysis. (Thesis). University of Missouri – Columbia. Retrieved from https://doi.org/10.32469/10355/59793

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Xu, Jia (Research scientist). “Stability, states, and interactions of the enzyme PMM/PGM by NMR and multivariate analysis: Stability, states, and interactions of the enzyme phosphomannomutase/phosphoglucomutase by nuclear magnetic resonance and multivariate analysis.” 2016. Thesis, University of Missouri – Columbia. Accessed March 03, 2021. https://doi.org/10.32469/10355/59793.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Xu, Jia (Research scientist). “Stability, states, and interactions of the enzyme PMM/PGM by NMR and multivariate analysis: Stability, states, and interactions of the enzyme phosphomannomutase/phosphoglucomutase by nuclear magnetic resonance and multivariate analysis.” 2016. Web. 03 Mar 2021.

Vancouver:

Xu J(s. Stability, states, and interactions of the enzyme PMM/PGM by NMR and multivariate analysis: Stability, states, and interactions of the enzyme phosphomannomutase/phosphoglucomutase by nuclear magnetic resonance and multivariate analysis. [Internet] [Thesis]. University of Missouri – Columbia; 2016. [cited 2021 Mar 03]. Available from: https://doi.org/10.32469/10355/59793.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Xu J(s. Stability, states, and interactions of the enzyme PMM/PGM by NMR and multivariate analysis: Stability, states, and interactions of the enzyme phosphomannomutase/phosphoglucomutase by nuclear magnetic resonance and multivariate analysis. [Thesis]. University of Missouri – Columbia; 2016. Available from: https://doi.org/10.32469/10355/59793

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Rutgers University

6. Jankowski, Wojciech, 1979-. Structural basis for the function of the Bcr-Abl protein substrate CrkL and human-CrkII as a novel partner for Cyclophilin A.

Degree: PhD, Animal Sciences, 2012, Rutgers University

URL: http://hdl.rutgers.edu/1782.1/rucore10001600001.ETD.000066832

►

Adaptor proteins are known to play an essential role in assembling protein-protein complexes which result in cellular signal propagation. Crk belongs to a family of… (more)

▼

Adaptor proteins are known to play an essential role in assembling protein-protein complexes which result in cellular signal propagation. Crk belongs to a family of adaptor proteins and was originally identified as an oncogene product of the CT10 retrovirus (v-Crk). Cellular homologues of v-Crk include CrkI, CrkII and CrkL. CrkI and CrkII are different splice variants, whereas CrkL is encoded by a distinct gene. Crk proteins contain one Src homology 2 (SH2) and one or two Src homology 3 (SH3) domains. Specific domain organization can assemble and activate a number of different ligands, including Abl. It remains poorly understood why CrkII and CrkL have distinct physiological roles despite showing similar domain structures, high sequence identity, and identical binding partners. Unlike CrkII, CrkL was found to be a key signaling molecule to interact with Bcr-Abl, which is a tyrosine kinase that plays a major role in Chronic Myeloid Leukemia(CML) pathogenesis. The interaction of CrkL with Bcr-Abl and its potent tyrosine phosphorylation (higher as compared to CrkII) is commonly used as a hallmark of Bcr-Abl kinase activity and response to tyrosine kinase inhibitors used in CML treatment. Knowing the differences in 3-dimensional structures between CrkII and CrkL would help to understand how these adaptors alter key signaling partners. However, the structure of CrkL is not available. Using NMR spectroscopy methodologies complemented by many other biochemical and biophysical techniques, we show that CrkL and phosphorylated CrkL structures are radically different from the corresponding structures of CrkII. The phosphorylation of Tyr221 (CrkII) and Tyr207 (CrkL) by Abl induces intramolecular binding to the SH2 domain, which in the case of phosphorylated CrkII was shown to completely abrogate signal transduction. In phosphorylated CrkL, however, the SH3N domain remains accessible and can form complexes. The data show that CrkL, unlike CrkII, forms a constitutive complex with Abl hence explaining the preference of Bcr-Abl for CrkL over CrkII. The results also highlight how the structural organization of the modular domains in adaptor proteins can control signaling outcome. In the second part we show that the Gly219−Pro220 motif of CrkII binds into theactive site cleft of CypA. In contrast, CrkL does not contain this GP motif and therefore, is not susceptible to CypA regulation. The interaction between CypA and CrkII occurs both in vitro and in vivo. CypA is recruited to the CrkII phosphorylation site (Tyr221), and delays phosphorylation by Abl. This is a novel role for CypA, which appears to act as a selective switch to modulate the level of phosphorylation of a signaling protein.

Advisors/Committee Members: Jankowski, Wojciech, 1979- (author), Kalodimos, Charalampos G (chair), Case, David A (internal member), Olson, Wilma K (internal member), Birge, Raymond (outside member).

Subjects/Keywords: Protein binding; Nuclear magnetic resonance spectroscopy

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Jankowski, Wojciech, 1. (2012). Structural basis for the function of the Bcr-Abl protein substrate CrkL and human-CrkII as a novel partner for Cyclophilin A. (Doctoral Dissertation). Rutgers University. Retrieved from http://hdl.rutgers.edu/1782.1/rucore10001600001.ETD.000066832

Chicago Manual of Style (16^th Edition):

Jankowski, Wojciech, 1979-. “Structural basis for the function of the Bcr-Abl protein substrate CrkL and human-CrkII as a novel partner for Cyclophilin A.” 2012. Doctoral Dissertation, Rutgers University. Accessed March 03, 2021. http://hdl.rutgers.edu/1782.1/rucore10001600001.ETD.000066832.

MLA Handbook (7^th Edition):

Jankowski, Wojciech, 1979-. “Structural basis for the function of the Bcr-Abl protein substrate CrkL and human-CrkII as a novel partner for Cyclophilin A.” 2012. Web. 03 Mar 2021.

Vancouver:

Jankowski, Wojciech 1. Structural basis for the function of the Bcr-Abl protein substrate CrkL and human-CrkII as a novel partner for Cyclophilin A. [Internet] [Doctoral dissertation]. Rutgers University; 2012. [cited 2021 Mar 03]. Available from: http://hdl.rutgers.edu/1782.1/rucore10001600001.ETD.000066832.

Council of Science Editors:

Jankowski, Wojciech 1. Structural basis for the function of the Bcr-Abl protein substrate CrkL and human-CrkII as a novel partner for Cyclophilin A. [Doctoral Dissertation]. Rutgers University; 2012. Available from: http://hdl.rutgers.edu/1782.1/rucore10001600001.ETD.000066832

7. Lucena Alcalde, Guillermo. New developments in chromatographic NMR.

Degree: PhD, 2018, University of Sussex

URL: http://sro.sussex.ac.uk/id/eprint/76636/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.751860

► Analysis in chemistry has always been hindered by the presence of impurities in samples or mixtures that are difficult to separate. Nuclear magnetic resonance has… (more)

▼ Analysis in chemistry has always been hindered by the presence of impurities in samples or mixtures that are difficult to separate. Nuclear magnetic resonance has proven to be one of the most powerful analysis techniques to enable the study of mixtures by pseudoseparation using molecular parameters such as the diffusion coefficient through the application of the DOSY technique. In order to extend the application of this technique, an improvement has been proposed know as matrix-assisted DOSY (MAD-DOSY) or chromatographic NMR. This technique is based on the addition of a sample modifier that will interact differently with the molecules, varying and separating their diffusion coefficients, or even changing slightly the chemical shifts. To extend the application of chromatographic NMR, size exclusion stationary phases have been combined with DOSY experiments. These studies have been applied to analyze mixtures modifying the diffusion coefficient in terms of size exclusion behavior and to increase the understanding of the interactions between the analytes and the stationary phase. These studies have been published in Magnetic Resonance in Chemistry. One of the main issues when using DOSY is spectral overlapping, which is the main cause of poor resolution. In addition to this problem, a consequence of using stationary phases is the appearance of increased broadening of the signals due to differences in magnetic susceptibility. Thus, to achieve the aim, the study of diffusion properties have been performed under HR-MAS conditions which can help to remove susceptibility effect, but has complicating effects on the DOSY experiment. A method to obtain reliable diffusion measurements under HR-MAS have been developed using a D2O sample. Different conditions have been investigated including different pulse sequences, variation of parameters of the pulse sequence (diffusion delay or gradient strength), spinning rate and synchronization of the pulse sequence with the sample spinning. Also improvements in sample preparation as the addition of spacers in different locations of the sample rotor, to both reduce radial field variations and the sample volume, in order to obtain the most accurate diffusion values. This method have been published in Magnetic Resonance in Chemistry. The method have been applied to a wide range of molecules to extend the understanding of diffusion under HR-MAS conditions. In order to extend the range of application of NMR chromatography, a complementary study of the analysis of a mixture of different enantiomers including ethylenediamine cobalt complexes, aminoacids and some other organic small molecules adding to the sample a chiral stationary phase as a sample modifier is included in the final chapter of this thesis.

Subjects/Keywords: 540; QD0096.N8 Nuclear magnetic resonance spectroscopy (including Fourier transform nuclear magnetic resonance spectroscopy)

10 more images…

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Lucena Alcalde, G. (2018). New developments in chromatographic NMR. (Doctoral Dissertation). University of Sussex. Retrieved from http://sro.sussex.ac.uk/id/eprint/76636/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.751860

Chicago Manual of Style (16^th Edition):

Lucena Alcalde, Guillermo. “New developments in chromatographic NMR.” 2018. Doctoral Dissertation, University of Sussex. Accessed March 03, 2021. http://sro.sussex.ac.uk/id/eprint/76636/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.751860.

MLA Handbook (7^th Edition):

Lucena Alcalde, Guillermo. “New developments in chromatographic NMR.” 2018. Web. 03 Mar 2021.

Vancouver:

Lucena Alcalde G. New developments in chromatographic NMR. [Internet] [Doctoral dissertation]. University of Sussex; 2018. [cited 2021 Mar 03]. Available from: http://sro.sussex.ac.uk/id/eprint/76636/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.751860.

Council of Science Editors:

Lucena Alcalde G. New developments in chromatographic NMR. [Doctoral Dissertation]. University of Sussex; 2018. Available from: http://sro.sussex.ac.uk/id/eprint/76636/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.751860

University of Illinois – Urbana-Champaign

8. Vartanian, Ariane M. Nuclear magnetic resonance studies of complex materials systems: from amplification to anisotropy.

Degree: PhD, Chemistry, 2016, University of Illinois – Urbana-Champaign

URL: http://hdl.handle.net/2142/90927

► This dissertation explores complex materials systems, with a special focus on developing nuclear resonance spectroscopy (NMR) techniques to decipher chemical environments at the molecular level.… (more)

Subjects/Keywords: Nuclear magnetic resonance (NMR) spectroscopy; nuclear magnetic resonance spectroscopy; anisotropic particles; chemical amplification

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Vartanian, A. M. (2016). Nuclear magnetic resonance studies of complex materials systems: from amplification to anisotropy. (Doctoral Dissertation). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/90927

Chicago Manual of Style (16^th Edition):

Vartanian, Ariane M. “Nuclear magnetic resonance studies of complex materials systems: from amplification to anisotropy.” 2016. Doctoral Dissertation, University of Illinois – Urbana-Champaign. Accessed March 03, 2021. http://hdl.handle.net/2142/90927.

MLA Handbook (7^th Edition):

Vartanian, Ariane M. “Nuclear magnetic resonance studies of complex materials systems: from amplification to anisotropy.” 2016. Web. 03 Mar 2021.

Vancouver:

Vartanian AM. Nuclear magnetic resonance studies of complex materials systems: from amplification to anisotropy. [Internet] [Doctoral dissertation]. University of Illinois – Urbana-Champaign; 2016. [cited 2021 Mar 03]. Available from: http://hdl.handle.net/2142/90927.

Council of Science Editors:

Vartanian AM. Nuclear magnetic resonance studies of complex materials systems: from amplification to anisotropy. [Doctoral Dissertation]. University of Illinois – Urbana-Champaign; 2016. Available from: http://hdl.handle.net/2142/90927

Vanderbilt University

9. Bowen, Ryan Scott. Structural Studies of N6-(Deoxy-D-Erythro-Pentofuranosyl)-2,6-Diamino-3,4-Dihydro-4-Oxo-5-N-Methylformamido-Pyrimidine and 8-(Deoxyguanosin-N2-yl)-1-Aminopyrene.

Degree: MS, Chemistry, 2016, Vanderbilt University

URL: http://hdl.handle.net/1803/11345

► N6-(Deoxy-D-Erythro-Pentofuranosyl)-2,6-Diamino-3,4-Dihydro-4-Oxo-5-N-Methylformamido-Pyrimidine (MeFapy-dG) is a deoxyribonucleic acid lesion that has been hypothesized to be induced by methylating chemotherapeutic agents. MeFapy-dG is known to block DNA replication,… (more)

Subjects/Keywords: fapy; aminopyrene; nuclear magnetic resonance; mefapy; nuclear magnetic resonance spectroscopy; solution structures; NMR; structural studies

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Bowen, R. S. (2016). Structural Studies of N6-(Deoxy-D-Erythro-Pentofuranosyl)-2,6-Diamino-3,4-Dihydro-4-Oxo-5-N-Methylformamido-Pyrimidine and 8-(Deoxyguanosin-N2-yl)-1-Aminopyrene. (Thesis). Vanderbilt University. Retrieved from http://hdl.handle.net/1803/11345

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Bowen, Ryan Scott. “Structural Studies of N6-(Deoxy-D-Erythro-Pentofuranosyl)-2,6-Diamino-3,4-Dihydro-4-Oxo-5-N-Methylformamido-Pyrimidine and 8-(Deoxyguanosin-N2-yl)-1-Aminopyrene.” 2016. Thesis, Vanderbilt University. Accessed March 03, 2021. http://hdl.handle.net/1803/11345.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Bowen, Ryan Scott. “Structural Studies of N6-(Deoxy-D-Erythro-Pentofuranosyl)-2,6-Diamino-3,4-Dihydro-4-Oxo-5-N-Methylformamido-Pyrimidine and 8-(Deoxyguanosin-N2-yl)-1-Aminopyrene.” 2016. Web. 03 Mar 2021.

Vancouver:

Bowen RS. Structural Studies of N6-(Deoxy-D-Erythro-Pentofuranosyl)-2,6-Diamino-3,4-Dihydro-4-Oxo-5-N-Methylformamido-Pyrimidine and 8-(Deoxyguanosin-N2-yl)-1-Aminopyrene. [Internet] [Thesis]. Vanderbilt University; 2016. [cited 2021 Mar 03]. Available from: http://hdl.handle.net/1803/11345.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Bowen RS. Structural Studies of N6-(Deoxy-D-Erythro-Pentofuranosyl)-2,6-Diamino-3,4-Dihydro-4-Oxo-5-N-Methylformamido-Pyrimidine and 8-(Deoxyguanosin-N2-yl)-1-Aminopyrene. [Thesis]. Vanderbilt University; 2016. Available from: http://hdl.handle.net/1803/11345

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

10. Zubkov, Mikhail. Development of novel magnetic resonance imaging pulse sequences for clinical applications.

Degree: 2015, Western Sydney University

URL: http://hdl.handle.net/1959.7/uws:36445

► Diffusion is a type of translational molecular motion playing a central role in a large number of physical, chemical and biological phenomena, the latter encompassing… (more)

▼ Diffusion is a type of translational molecular motion playing a central role in a large number of physical, chemical and biological phenomena, the latter encompassing in vitro as well as in vivo processes. Diffusion studies with nuclear magnetic resonance (NMR) have long proven to be a robust and versatile method in both fundamental and applied research. Despite providing extraordinary measurement precision for most single-component homogeneous liquid samples, the two basic measurement techniques in diffusion NMR imaging and spectroscopy, i.e., pulsed gradient spin-echo and pulsed gradient stimulated echo (PGSE and PGSTE) have a number of drawbacks. These often result in either an increased number of experiments, a longer single experiment duration or additional post-processing. Modifying the PGSE and PGSTE pulse sequences or their method of execution is known to help overcome some of the complications. This work addresses two reasons classic diffusion NMR experiments often prove ineffective. The first issue is responsible for longer durations of single experiments and results from the consistency between experiments being provided by starting the measurement from an equilibrium state of magnetization – typically thermodynamic equilibrium. On the other hand, consistency can be achieved by using a different state of magnetization, characterized by dynamic equilibrium, i.e., the steady state. A steady state is known to form if the experiment is repeated rapidly enough, yet the diffusion manifestation in the steady state has not yet been well described even though it is the default execution mode in most diffusion NMR imaging studies. In order to provide such a description, the Bloch equations were solved for a PGSE experiment employing two radiofrequency pulses and an arbitrary magnetic field gradient waveform. The theoretical description was tested for the case of isotropic diffusion in a polyethylene glycol/water solution and for the anisotropic case using a lyotropic liquid crystal sample. Computer simulations were also performed for the isotropic diffusion case. The results of isotropic diffusion measurements differed from the reference values when steady state effects were not accounted for. The theoretical description and computer simulations developed on the other hand showed close agreement with the control measurements. In contrast, anisotropic diffusion measurements showed no difference between the two approaches, which can be attributed to the relaxation properties of the sample. The criteria for distinguishing between the cases of classic and steady state descriptions of NMR diffusion measurements were proposed based on these results. Another reason for complications in diffusion NMR imaging experiments appears when there are multiple diffusing components (usually two, although more can be present) in the studied system or sample. In such a case conventional data analysis which provides a single diffusion coefficient (or diffusion tensor if the diffusion is anisotropic) yields non-meaningful results. A… Advisors/Committee Members: University of Western Sydney. School of Science and Health (Host institution).

Subjects/Keywords: nuclear magnetic resonance spectroscopy; diffusion; nuclear magnetic resonance; Thesis (Ph.D.) – University of Western Sydney, 2015

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Zubkov, M. (2015). Development of novel magnetic resonance imaging pulse sequences for clinical applications. (Thesis). Western Sydney University. Retrieved from http://hdl.handle.net/1959.7/uws:36445

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Zubkov, Mikhail. “Development of novel magnetic resonance imaging pulse sequences for clinical applications.” 2015. Thesis, Western Sydney University. Accessed March 03, 2021. http://hdl.handle.net/1959.7/uws:36445.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Zubkov, Mikhail. “Development of novel magnetic resonance imaging pulse sequences for clinical applications.” 2015. Web. 03 Mar 2021.

Vancouver:

Zubkov M. Development of novel magnetic resonance imaging pulse sequences for clinical applications. [Internet] [Thesis]. Western Sydney University; 2015. [cited 2021 Mar 03]. Available from: http://hdl.handle.net/1959.7/uws:36445.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Zubkov M. Development of novel magnetic resonance imaging pulse sequences for clinical applications. [Thesis]. Western Sydney University; 2015. Available from: http://hdl.handle.net/1959.7/uws:36445

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Delaware

11. Yehl, Jenna B. Atomic-resolution characterization of actin-binding protein, cofilin-2, in complex with two nucleotide-states of F-actin, by magic angle spinning NMR spectroscopy.

Degree: PhD, University of Delaware, Department of Chemistry and Biochemistry, 2016, University of Delaware

URL: http://udspace.udel.edu/handle/19716/21472

► Cofilin, an actin-binding protein, is critical for actin dynamics within the cell. Actin dynamics are responsible within the cell for many essential cellular processes such… (more)

Subjects/Keywords: Actin.; Carrier proteins.; Nucleotides.; High resolution spectroscopy.; Nuclear magnetic resonance spectroscopy.

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Yehl, J. B. (2016). Atomic-resolution characterization of actin-binding protein, cofilin-2, in complex with two nucleotide-states of F-actin, by magic angle spinning NMR spectroscopy. (Doctoral Dissertation). University of Delaware. Retrieved from http://udspace.udel.edu/handle/19716/21472

Chicago Manual of Style (16^th Edition):

Yehl, Jenna B. “Atomic-resolution characterization of actin-binding protein, cofilin-2, in complex with two nucleotide-states of F-actin, by magic angle spinning NMR spectroscopy.” 2016. Doctoral Dissertation, University of Delaware. Accessed March 03, 2021. http://udspace.udel.edu/handle/19716/21472.

MLA Handbook (7^th Edition):

Yehl, Jenna B. “Atomic-resolution characterization of actin-binding protein, cofilin-2, in complex with two nucleotide-states of F-actin, by magic angle spinning NMR spectroscopy.” 2016. Web. 03 Mar 2021.

Vancouver:

Yehl JB. Atomic-resolution characterization of actin-binding protein, cofilin-2, in complex with two nucleotide-states of F-actin, by magic angle spinning NMR spectroscopy. [Internet] [Doctoral dissertation]. University of Delaware; 2016. [cited 2021 Mar 03]. Available from: http://udspace.udel.edu/handle/19716/21472.

Council of Science Editors:

Yehl JB. Atomic-resolution characterization of actin-binding protein, cofilin-2, in complex with two nucleotide-states of F-actin, by magic angle spinning NMR spectroscopy. [Doctoral Dissertation]. University of Delaware; 2016. Available from: http://udspace.udel.edu/handle/19716/21472

University of Oxford

12. Clarke, William. Human cardiac magnetic resonance spectroscopy.

Degree: PhD, 2016, University of Oxford

URL: https://ora.ox.ac.uk/objects/uuid:b75351dc-e4eb-4856-b901-4ba486ffe175 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.730198

► The status of the myocardial 'high energy phosphate' metabolism is a sensitive marker of the occurrence and progression of heart failure. Magnetic resonance spectroscopy enables… (more)

▼ The status of the myocardial 'high energy phosphate' metabolism is a sensitive marker of the occurrence and progression of heart failure. Magnetic resonance spectroscopy enables non-invasive, direct and potentially quantitative measurements of the phosphate containing metabolites present in the human myocardium. This thesis is primarily concerned with the creation of measurement techniques for cardiac phosphorus magnetic resonance spectroscopy (³¹P-MRS) at the 7 tesla field strength. Chapter 1 provides an overview of the physical basis of magnetic resonance spectroscopy, the myocardial high energy phosphate metabolism, and the clinical relevance of the technique. Chapter 2 describes the advantage of 7 tesla scanners over lower field strengths. The radio frequency coil hardware is characterised experimentally. The multivoxel spectroscopy methods used throughout the thesis are described. Chapter 3 details the implementation of an open source spectroscopy fitting program. It is validated against previous closed-source implementations. The program's use is demonstrated in several clinical studies of heart failure, and to improve a previously implemented ¹H spectroscopy coil combination method. In Chapter 4 the measurement of inorganic phosphate in the presence of overlapping peaks is attempted. Suppression of overlapping peaks, originating from the blood, is tried using B_o gradients, then saturation transfer. The myocardial pH of hypertrophic cardiomyopathy patients is measured. Chapter 5 describes the effect of creatine kinase catalysed chemical exchange on the ³¹P-MRS spectrum. A survey of methods suitable for measuring creatine kinase kinetics at 7 tesla is made. Multi-parametric fitting of variable repetition time saturation transfer data is explored in simulation and experiment. Chapter 6 describes the re-implementation and extension, for dynamic measurements, of the triple repetition time saturation transfer method for two clinical studies at 3 tesla. The creatine kinase forward rate constant is measured in heart failure and healthy cohorts, at rest, and during cardiac stress. In Chapter 7 a Bloch-Siegert B₁ mapping sequence is implemented for ³¹P-MRS. An optimal Bloch-Siegert method for X-nuclear spectroscopy is calculated. B₁maps are validated in skeletal muscle and collected in 5 volunteer's hearts. Chapter 8 uses the Bloch-Siegert B₁ mapping sequence and the four angle saturation transfer method to implement creatine kinase rate measurement at 7 tesla. The first 3D localised creatine kinase rate measurements in the human myocardium are achieved in 10 volunteers.

Subjects/Keywords: 616.1; Nuclear magnetic resonance spectroscopy; Human cardiac spectrsocopy; Phosphorus spectroscopy; 31P

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Clarke, W. (2016). Human cardiac magnetic resonance spectroscopy. (Doctoral Dissertation). University of Oxford. Retrieved from https://ora.ox.ac.uk/objects/uuid:b75351dc-e4eb-4856-b901-4ba486ffe175 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.730198

Chicago Manual of Style (16^th Edition):

Clarke, William. “Human cardiac magnetic resonance spectroscopy.” 2016. Doctoral Dissertation, University of Oxford. Accessed March 03, 2021. https://ora.ox.ac.uk/objects/uuid:b75351dc-e4eb-4856-b901-4ba486ffe175 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.730198.

MLA Handbook (7^th Edition):

Clarke, William. “Human cardiac magnetic resonance spectroscopy.” 2016. Web. 03 Mar 2021.

Vancouver:

Clarke W. Human cardiac magnetic resonance spectroscopy. [Internet] [Doctoral dissertation]. University of Oxford; 2016. [cited 2021 Mar 03]. Available from: https://ora.ox.ac.uk/objects/uuid:b75351dc-e4eb-4856-b901-4ba486ffe175 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.730198.

Council of Science Editors:

Clarke W. Human cardiac magnetic resonance spectroscopy. [Doctoral Dissertation]. University of Oxford; 2016. Available from: https://ora.ox.ac.uk/objects/uuid:b75351dc-e4eb-4856-b901-4ba486ffe175 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.730198

University of Lethbridge

13. University of Lethbridge. Faculty of Arts and Science. A nuclear magnetic resonance spectroscopic investigation of the molecular structure and aggregation behavior of asphaltenes .

Degree: 2015, University of Lethbridge

URL: http://hdl.handle.net/10133/4526

► The molecular and aggregate structure of asphaltenes derived from oil-sands bitumen, heavy black-oil and coal, and their aggregation behavior, have been studied comprehensively using solution-… (more)

Subjects/Keywords: Spectroscopy; Nuclear magnetic resonance spectroscopy; Petroleum; Solid-state NMR; Asphaltenes

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Science, U. o. L. F. o. A. a. (2015). A nuclear magnetic resonance spectroscopic investigation of the molecular structure and aggregation behavior of asphaltenes . (Thesis). University of Lethbridge. Retrieved from http://hdl.handle.net/10133/4526

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Science, University of Lethbridge. Faculty of Arts and. “A nuclear magnetic resonance spectroscopic investigation of the molecular structure and aggregation behavior of asphaltenes .” 2015. Thesis, University of Lethbridge. Accessed March 03, 2021. http://hdl.handle.net/10133/4526.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Science, University of Lethbridge. Faculty of Arts and. “A nuclear magnetic resonance spectroscopic investigation of the molecular structure and aggregation behavior of asphaltenes .” 2015. Web. 03 Mar 2021.

Vancouver:

Science UoLFoAa. A nuclear magnetic resonance spectroscopic investigation of the molecular structure and aggregation behavior of asphaltenes . [Internet] [Thesis]. University of Lethbridge; 2015. [cited 2021 Mar 03]. Available from: http://hdl.handle.net/10133/4526.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Science UoLFoAa. A nuclear magnetic resonance spectroscopic investigation of the molecular structure and aggregation behavior of asphaltenes . [Thesis]. University of Lethbridge; 2015. Available from: http://hdl.handle.net/10133/4526

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Missouri – Columbia

14. Oshokoya, Olayinka. Development of advanced chemometric methods for analysis of deep-ultraviolet resonance Raman and circular dichroism spectroscopic data for protein secondary structure determination.

Degree: 2015, University of Missouri – Columbia

URL: http://hdl.handle.net/10355/46886

► Determination of protein secondary structure has become an area of great importance in biochemistry and biophysics as protein secondary structure is directly related to protein… (more)

▼ Determination of protein secondary structure has become an area of great importance in biochemistry and biophysics as protein secondary structure is directly related to protein function and protein related diseases. While NMR and x-ray crystallography can predict placement of each atom in proteins to within an angstrom, optical methods are the preferred techniques for rapid evaluation of protein secondary structure content. Such techniques require calibration data to predict unknown protein secondary structure content where accuracy may be improved with the application of multivariate analysis. We compare protein secondary structure predictions obtained from multivariate analysis of ultraviolet resonance Raman (UVRR) and circular dichroism (CD) spectroscopic data using classical and partial least squares, and multivariate curve resolution-alternating least squares is made. Based on this analysis, the suggested best approach to rapid and accurate secondary structure determination is a combination of both CD and UVRR spectroscopy. While initial studies suggest that a complementary use of spectroscopic data from optical methods such as circular dichroism (CD), infrared (IR) and ultraviolet resonance Raman (UVRR) coupled with multivariate calibration techniques like multivariate curve resolution-alternating least squares (MCR-ALS) is the preferred route for real-time and accurate evaluation of protein secondary structure, further study presents a new strategy for the improvement of secondary structure determination of proteins by fusing CD and UVRR spectroscopic data. Also, a new method for determining the structural composition of each protein is employed, which is based on the relative abundance of the (phi,psi) dihedral angles of the peptide backbone as they correspond to each type of secondary structure. Comparison of the predicted protein secondary structures from MCR-ALS analysis of CD, UVRR and fused data with definitions obtained from dihedral angles of the peptide backbone, yields lower overall root mean squared errors of calibration for helical, sheet, poly-proline II type and total unfolded secondary structures with fused data. Considering that a disadvantage of multivariate calibration methods is the requirement of known concentration or spectral profiles, and second-order calibration methods, such as parallel factor analysis (PARAFAC), do not have such a requirement due to the "second-order advantage", PARAFAC was employed for analysis of UVRR data. An exceptional feature of UVRR spectroscopy is that UVRR spectra are also dependent on excitation wavelength as they are on secondary structure composition. Thus, higher order data can be created by combining protein UVRR spectra of several proteins collected at multiple excitation wavelengths. PARAFAC has been used to analyze UVRR data collected at multiple excitation wavelengths on several proteins to determine secondary structure content. Advisors/Committee Members: Jiji, Renee Denise (advisor).

Subjects/Keywords: Proteins – Structure; Nuclear magnetic resonance spectroscopy; Raman spectroscopy

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Oshokoya, O. (2015). Development of advanced chemometric methods for analysis of deep-ultraviolet resonance Raman and circular dichroism spectroscopic data for protein secondary structure determination. (Thesis). University of Missouri – Columbia. Retrieved from http://hdl.handle.net/10355/46886

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Oshokoya, Olayinka. “Development of advanced chemometric methods for analysis of deep-ultraviolet resonance Raman and circular dichroism spectroscopic data for protein secondary structure determination.” 2015. Thesis, University of Missouri – Columbia. Accessed March 03, 2021. http://hdl.handle.net/10355/46886.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Oshokoya, Olayinka. “Development of advanced chemometric methods for analysis of deep-ultraviolet resonance Raman and circular dichroism spectroscopic data for protein secondary structure determination.” 2015. Web. 03 Mar 2021.

Vancouver:

Oshokoya O. Development of advanced chemometric methods for analysis of deep-ultraviolet resonance Raman and circular dichroism spectroscopic data for protein secondary structure determination. [Internet] [Thesis]. University of Missouri – Columbia; 2015. [cited 2021 Mar 03]. Available from: http://hdl.handle.net/10355/46886.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Oshokoya O. Development of advanced chemometric methods for analysis of deep-ultraviolet resonance Raman and circular dichroism spectroscopic data for protein secondary structure determination. [Thesis]. University of Missouri – Columbia; 2015. Available from: http://hdl.handle.net/10355/46886

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Michigan State University

15. Voss, Philip Jonathan. Recoil Distance Method lifetime measurements via gamma-ray and charged-particle spectroscopy at NSCL.

Degree: 2011, Michigan State University

URL: http://etd.lib.msu.edu/islandora/object/etd:945

►

Thesis Ph. D. Michigan State University. Physics 2011.

The Recoil Distance Method (RDM) is a well-established technique for measuring lifetimes of electromagnetic transitions. Transition matrix… (more)

Subjects/Keywords: Nuclear magnetic resonance spectroscopy; Exotic nuclei; Nuclear physics; Physics

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Voss, P. J. (2011). Recoil Distance Method lifetime measurements via gamma-ray and charged-particle spectroscopy at NSCL. (Thesis). Michigan State University. Retrieved from http://etd.lib.msu.edu/islandora/object/etd:945

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Voss, Philip Jonathan. “Recoil Distance Method lifetime measurements via gamma-ray and charged-particle spectroscopy at NSCL.” 2011. Thesis, Michigan State University. Accessed March 03, 2021. http://etd.lib.msu.edu/islandora/object/etd:945.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Voss, Philip Jonathan. “Recoil Distance Method lifetime measurements via gamma-ray and charged-particle spectroscopy at NSCL.” 2011. Web. 03 Mar 2021.

Vancouver:

Voss PJ. Recoil Distance Method lifetime measurements via gamma-ray and charged-particle spectroscopy at NSCL. [Internet] [Thesis]. Michigan State University; 2011. [cited 2021 Mar 03]. Available from: http://etd.lib.msu.edu/islandora/object/etd:945.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Voss PJ. Recoil Distance Method lifetime measurements via gamma-ray and charged-particle spectroscopy at NSCL. [Thesis]. Michigan State University; 2011. Available from: http://etd.lib.msu.edu/islandora/object/etd:945

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Indian Institute of Science

16. Lobo, Nitin Prakash. NMR Methods For The Study Of Partially Ordered Systems.

Degree: PhD, Faculty of Science, 2016, Indian Institute of Science

URL: http://etd.iisc.ac.in/handle/2005/2588

► The work presented in this thesis has two parts. The first part deals with methodological developments in the area of solid-state NMR, relevant to the… (more)

▼ The work presented in this thesis has two parts. The first part deals with methodological developments in the area of solid-state NMR, relevant to the study of partially ordered systems. Liquid crystals are best examples of such partially ordered systems and they are easily oriented by the magnetic field used for the NMR study. They provide spectra rich in information useful for the study of structure and dynamic s of the oriented molecule. Dipolar couplings and anisotropic chemical shifts are relatively easy to obtain for these systems. However, the methodologies used for extracting the required information are constantly undergoing change, with newer ideas being used for optimal use of the technique and increasing the sensitivity of the methodology. In this thesis, existing methods used for obtaining dipolar couplings from oriented liquid crystalline samples are examined in detail and conditions for optimal use of the methods are investigated. Different approaches for enhancing the sensitivity of the techniques are also proposed. Estimation of chemical shift anisotropy of carbons for a molecule that is used as a building block for several mesogens has been obtained and its utility for estimating the order parameters of the system have been examined. The second part of the thesis deals with the application of solid state NMR methods to the study of a number of novel liquid crystalline systems and for the estimation of dynamics, order and orientation of the mesogenic molecules in the magnetic field. Chapter-2 deals with a detailed and systematic study to improve the sensitivity of cross-polarization based separated local field (SLF) NMR spectroscopy techniques such as PISEMA(Polarization Inversion Spin Exchange at the Magic Angle) and PDLF(Pro-ton Detected Local Field). The chapter has been further divided into three sections. Section-A describes the optimization procedure for cross-polarization period for reducing zero-frequency peaks in SLF experiments. Polarization Inversion(PI) is one of the important components of PISEMA and plays a crucial role in enhancing the dipolar cross-peaks and suppressing the axial-peaks. Shortening this period has the advantage of less r.f. power input into the system, thus less susceptibility to sample heating. Therefore it is crucial to arrive at the optimum condition for which maximum sensitivity and resolution are obtained. A detailed experimental investigation of the role of the initial po1arization period has been carried out for two different samples of static oriented liquid crystalline material at two different temperatures and a contact time of 2ms has been found to be optimal for such samples. Insection-B of this chapter, the initial preparation period of the experiment is considered as a possible means of increasing the sensitivity of the experiment. Thus the use of cross-polarization via the dipolar bath by the use of a diabatic demagnetization in the rotating frame(ADRF-CP) has been proposed to be incorporated into PISEMA. To understand the CP dynamics, magnetization in… Advisors/Committee Members: Ramanathan, K V (advisor).

Subjects/Keywords: Hamiltonian Systems; Partially Ordered Systems; Nuclear Magnetic Resonance; Solid State Nuclear Magnetic Resonance; Liquid Crystal Nuclear Magnetic Resonance; Mesogens - Nuclear Magnetic Resonance; Nuclear Spin Hamiltonian; Dipolar Coupling; Chemical Shift Anisotropy; Nuclear Magnetic Resonance Spectroscopy; Seperated Local Field (SLF) NMR Spectroscopy; 13C NMR Spectroscopy; Thiophene; 13CNMR; Magnetism

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Lobo, N. P. (2016). NMR Methods For The Study Of Partially Ordered Systems. (Doctoral Dissertation). Indian Institute of Science. Retrieved from http://etd.iisc.ac.in/handle/2005/2588

Chicago Manual of Style (16^th Edition):

Lobo, Nitin Prakash. “NMR Methods For The Study Of Partially Ordered Systems.” 2016. Doctoral Dissertation, Indian Institute of Science. Accessed March 03, 2021. http://etd.iisc.ac.in/handle/2005/2588.

MLA Handbook (7^th Edition):

Lobo, Nitin Prakash. “NMR Methods For The Study Of Partially Ordered Systems.” 2016. Web. 03 Mar 2021.

Vancouver:

Lobo NP. NMR Methods For The Study Of Partially Ordered Systems. [Internet] [Doctoral dissertation]. Indian Institute of Science; 2016. [cited 2021 Mar 03]. Available from: http://etd.iisc.ac.in/handle/2005/2588.

Council of Science Editors:

Lobo NP. NMR Methods For The Study Of Partially Ordered Systems. [Doctoral Dissertation]. Indian Institute of Science; 2016. Available from: http://etd.iisc.ac.in/handle/2005/2588

Durban University of Technology

17. Ross, Ashley Hilton Adrian. An evaluation of Hahnemannian quinquagenimillesimal potencies using nuclear magnetic resonance spectroscopy.

Degree: 1997, Durban University of Technology

URL: http://hdl.handle.net/10321/1936

►

Dissertation submitted in partial compliance with the requirements for the Master's Degree in Technology: Homoeopathy, Technikon Natal, 1997.

The purpose of this investigation was to… (more)

Subjects/Keywords: Homeopathy; Nuclear magnetic resonance spectroscopy

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Ross, A. H. A. (1997). An evaluation of Hahnemannian quinquagenimillesimal potencies using nuclear magnetic resonance spectroscopy. (Thesis). Durban University of Technology. Retrieved from http://hdl.handle.net/10321/1936

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Ross, Ashley Hilton Adrian. “An evaluation of Hahnemannian quinquagenimillesimal potencies using nuclear magnetic resonance spectroscopy.” 1997. Thesis, Durban University of Technology. Accessed March 03, 2021. http://hdl.handle.net/10321/1936.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Ross, Ashley Hilton Adrian. “An evaluation of Hahnemannian quinquagenimillesimal potencies using nuclear magnetic resonance spectroscopy.” 1997. Web. 03 Mar 2021.

Vancouver:

Ross AHA. An evaluation of Hahnemannian quinquagenimillesimal potencies using nuclear magnetic resonance spectroscopy. [Internet] [Thesis]. Durban University of Technology; 1997. [cited 2021 Mar 03]. Available from: http://hdl.handle.net/10321/1936.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Ross AHA. An evaluation of Hahnemannian quinquagenimillesimal potencies using nuclear magnetic resonance spectroscopy. [Thesis]. Durban University of Technology; 1997. Available from: http://hdl.handle.net/10321/1936

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Dalhousie University

18. Langelaan, David. Structural Studies Of Apelin And Its Receptor As Well As The Characteristics And Causes Of Membrane Protein Helix Kinks.

Degree: PhD, Department of Biochemistry & Molecular Biology, 2013, Dalhousie University

URL: http://hdl.handle.net/10222/22285

► Apelin, the endogenous ligand to the apelin receptor, is a small peptide involved with cardiovascular regulation. Using nuclear magnetic resonance (NMR) spectroscopy, I demonstrate that… (more)

▼ Apelin, the endogenous ligand to the apelin receptor, is a small peptide involved with cardiovascular regulation. Using nuclear magnetic resonance (NMR) spectroscopy, I demonstrate that at low temperature, residues R6-L9 and G13-F17 of apelin are more structured than the rest of the peptide. I also study the interactions of apelin with sodium dodecylsulphate (SDS), dodecylphosphocholine (DPC) and 1-palmitoyl-2-hydroxy-sn- glycero-3-[phospho-RAC-(1-glycerol)] (LPPG) micelles. Apelin binds to SDS micelles through residues R6-L9, with structure being induced in this region as well as the C- terminus of the peptide. The binding to micelles along with the corresponding change in structure make it likely that apelin binds to the apelin receptor following the membrane catalysis hypothesis. NMR spectroscopy was used to determine the structure of the N- terminal tail and first transmembrane segment of the apelin receptor (AR55) in DPC micelles. AR55 has two disrupted helices from D14-K25 and from A29-K57. The second helix is the membrane spanning region of AR55 and has a significant kink located at N46. Mutagenesis of the apelin receptor and functional assays indicate that G42, G45 and N46 are essential for the proper trafficking and function of AR. In the N-terminal tail, the functionally critical residues E20 and D23 form an anionic face that could take part in initial binding of apelin to AR. The structure of AR55 was also determined in SDS micelles, LPPG micelles and a 1:1 water: 1,1,1,3,3,3-hexafluoroisopropanol (HFIP) solution. Overall, the micelle spanning region of AR55 has a consistent structure with a kink near N46. The N-terminal tail of AR55 is more variable, having similar structures in the micelle conditions but being largely helical in 50% HFIP. NMR relaxation experiments indicate that the N-terminal tail of AR55 undergoes much more motion in LPPG micelles compared to SDS and DPC micelles. Finally, I created a program named MC-HELAN that characterizes the kinks that occur in protein helices. I used MC- HELAN to analyze all non-redundant membrane protein structures as of March 2010. Membrane protein helix kinks are remarkably common and diverse. Initial attempts to predict membrane protein kinks using only the protein sequence were unsuccessful. Advisors/Committee Members: Dr. Pierre Lavigne (external-examiner), Dr. John Archibald (graduate-coordinator), Dr. Roy Duncan (thesis-reader), Dr. Roger McLeod (thesis-reader), Dr. Stephen Bearne (thesis-reader), Dr. Jan Rainey (thesis-supervisor), Not Applicable (ethics-approval), Not Applicable (manuscripts), Not Applicable (copyright-release).

Subjects/Keywords: G-protein coupled receptor; Nuclear magnetic resonance spectroscopy; Apelin

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Langelaan, D. (2013). Structural Studies Of Apelin And Its Receptor As Well As The Characteristics And Causes Of Membrane Protein Helix Kinks. (Doctoral Dissertation). Dalhousie University. Retrieved from http://hdl.handle.net/10222/22285

Chicago Manual of Style (16^th Edition):

Langelaan, David. “Structural Studies Of Apelin And Its Receptor As Well As The Characteristics And Causes Of Membrane Protein Helix Kinks.” 2013. Doctoral Dissertation, Dalhousie University. Accessed March 03, 2021. http://hdl.handle.net/10222/22285.

MLA Handbook (7^th Edition):

Langelaan, David. “Structural Studies Of Apelin And Its Receptor As Well As The Characteristics And Causes Of Membrane Protein Helix Kinks.” 2013. Web. 03 Mar 2021.

Vancouver:

Langelaan D. Structural Studies Of Apelin And Its Receptor As Well As The Characteristics And Causes Of Membrane Protein Helix Kinks. [Internet] [Doctoral dissertation]. Dalhousie University; 2013. [cited 2021 Mar 03]. Available from: http://hdl.handle.net/10222/22285.

Council of Science Editors:

Langelaan D. Structural Studies Of Apelin And Its Receptor As Well As The Characteristics And Causes Of Membrane Protein Helix Kinks. [Doctoral Dissertation]. Dalhousie University; 2013. Available from: http://hdl.handle.net/10222/22285

Rochester Institute of Technology

19. Luke, Barbara J. Use of gadolinium in 13C NMR studies.

Degree: School of Chemistry and Materials Science (COS), 1980, Rochester Institute of Technology

URL: https://scholarworks.rit.edu/theses/5959

► The addition of the paramagnetic reagents gadolinium(18- crown-6) nitrate, gadolinium(dicyclohexano-18-crown-6) nitrate, and gadolinium nitrate pentahydrate to each of the substrates ethylbenzene, and thymidine has been… (more)

Subjects/Keywords: Nuclear magnetic resonance spectroscopy; Gadolinium

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Luke, B. J. (1980). Use of gadolinium in 13C NMR studies. (Thesis). Rochester Institute of Technology. Retrieved from https://scholarworks.rit.edu/theses/5959

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Luke, Barbara J. “Use of gadolinium in 13C NMR studies.” 1980. Thesis, Rochester Institute of Technology. Accessed March 03, 2021. https://scholarworks.rit.edu/theses/5959.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Luke, Barbara J. “Use of gadolinium in 13C NMR studies.” 1980. Web. 03 Mar 2021.

Vancouver:

Luke BJ. Use of gadolinium in 13C NMR studies. [Internet] [Thesis]. Rochester Institute of Technology; 1980. [cited 2021 Mar 03]. Available from: https://scholarworks.rit.edu/theses/5959.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Luke BJ. Use of gadolinium in 13C NMR studies. [Thesis]. Rochester Institute of Technology; 1980. Available from: https://scholarworks.rit.edu/theses/5959

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Alberta

20. Sit, Clarissa Sau-Wei. Structural Elucidation of Thuricin CD, Thurincin H and a Leucocin A Mutant.

Degree: PhD, Department of Chemistry, 2012, University of Alberta

URL: https://era.library.ualberta.ca/files/3f4626234

► Thuricin CD, a two-component bacteriocin produced by Bacillus thuringiensis DPC 6431, exhibits potent activity against the hospital superbug Clostridium difficile ribotype O27. The two peptides… (more)

▼ Thuricin CD, a two-component bacteriocin produced by Bacillus thuringiensis DPC 6431, exhibits potent activity against the hospital superbug Clostridium difficile ribotype O27. The two peptides (Trn-α and Trn-β) that constitute thuricin CD operate synergistically to kill sensitive bacteria at nanomolar concentrations. Characterization of Trn-α and Trn-β by mass spectrometry established that each peptide is 6 mass units lighter than predicted from the sequence of its structural gene, suggesting that the peptides undergo post-translational modification. Analysis of nuclear Overhauser effect (NOE) data from NMR experiments run on [13C, 15N]Trn-α and [13C, 15N]Trn-β indicate that each peptide features three sulfur to α-carbon (S-Cα) thioether bridges between Cys5 and residue 28, Cys9 and residue 25, and Cys13 and residue 21. To elucidate the stereochemistry of these bridges, the 3D structures of the eight possible stereoisomers for each peptide were calculated and compared to determine which stereoisomer best fit the NOE data. The most representative structures of Trn-α and Trn-β both feature L-stereochemistry at residue 21 (α-R), L-stereochemistry at residue 25 (α-R), and D-stereochemistry at residue 28 (α-S). Thurincin H is a single-component bacteriocin produced by B. thuringiensis SF361 that is highly active against the human pathogen Listeria monocytogenes. Mass spectrometry analysis revealed that thurincin H is 8 mass units lighter than expected from its genetic sequence. NOE experiments on [13C, 15N]thurincin H provided evidence for the presence of four S-Cα bridges in the peptide. Out of the 16 possible stereoisomers, the stereoisomer that features D-stereochemistry (α-S) at all four sulfur-linked α-carbons gave the most representative 3D solution structure of thurincin H. Leucocin A is an antilisterial bacteriocin with a disulfide bridge between Cys9 and Cys14. Previous studies showed that replacement of the cysteines with phenylalanines had no effect on the peptide’s activity, while replacement with serines resulted in complete loss of activity. [13C, 15N]-(C9S, C14S)-leucocin A, produced by heterologous expression, gave an elongated C-terminal α-helix and a disordered N-terminus compared to the 3D structure of wild-type leucocin A, thus providing a potential explanation for the loss in activity. Studies are underway to determine the 3D structure of (C9F, C14F)-leucocin A.

Subjects/Keywords: leucocin; thuricin; spectroscopy; structure; bacteriocin; nuclear magnetic resonance; thurincin

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Sit, C. S. (2012). Structural Elucidation of Thuricin CD, Thurincin H and a Leucocin A Mutant. (Doctoral Dissertation). University of Alberta. Retrieved from https://era.library.ualberta.ca/files/3f4626234

Chicago Manual of Style (16^th Edition):

Sit, Clarissa Sau-Wei. “Structural Elucidation of Thuricin CD, Thurincin H and a Leucocin A Mutant.” 2012. Doctoral Dissertation, University of Alberta. Accessed March 03, 2021. https://era.library.ualberta.ca/files/3f4626234.

MLA Handbook (7^th Edition):

Sit, Clarissa Sau-Wei. “Structural Elucidation of Thuricin CD, Thurincin H and a Leucocin A Mutant.” 2012. Web. 03 Mar 2021.

Vancouver:

Sit CS. Structural Elucidation of Thuricin CD, Thurincin H and a Leucocin A Mutant. [Internet] [Doctoral dissertation]. University of Alberta; 2012. [cited 2021 Mar 03]. Available from: https://era.library.ualberta.ca/files/3f4626234.

Council of Science Editors:

Sit CS. Structural Elucidation of Thuricin CD, Thurincin H and a Leucocin A Mutant. [Doctoral Dissertation]. University of Alberta; 2012. Available from: https://era.library.ualberta.ca/files/3f4626234

University of Alberta

21. Baleja, James D. The structural basis of DNA-protein recognition: a nuclear magnetic resonance determination of the structure of DNA and DNA-Cro repressor interactions.

Degree: PhD, Department of Biochemistry, 1990, University of Alberta

URL: https://era.library.ualberta.ca/files/8c97ks912

Subjects/Keywords: Nuclear magnetic resonance spectroscopy.; DNA.

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Baleja, J. D. (1990). The structural basis of DNA-protein recognition: a nuclear magnetic resonance determination of the structure of DNA and DNA-Cro repressor interactions. (Doctoral Dissertation). University of Alberta. Retrieved from https://era.library.ualberta.ca/files/8c97ks912

Chicago Manual of Style (16^th Edition):

Baleja, James D. “The structural basis of DNA-protein recognition: a nuclear magnetic resonance determination of the structure of DNA and DNA-Cro repressor interactions.” 1990. Doctoral Dissertation, University of Alberta. Accessed March 03, 2021. https://era.library.ualberta.ca/files/8c97ks912.

MLA Handbook (7^th Edition):

Baleja, James D. “The structural basis of DNA-protein recognition: a nuclear magnetic resonance determination of the structure of DNA and DNA-Cro repressor interactions.” 1990. Web. 03 Mar 2021.

Vancouver:

Baleja JD. The structural basis of DNA-protein recognition: a nuclear magnetic resonance determination of the structure of DNA and DNA-Cro repressor interactions. [Internet] [Doctoral dissertation]. University of Alberta; 1990. [cited 2021 Mar 03]. Available from: https://era.library.ualberta.ca/files/8c97ks912.

Council of Science Editors:

Baleja JD. The structural basis of DNA-protein recognition: a nuclear magnetic resonance determination of the structure of DNA and DNA-Cro repressor interactions. [Doctoral Dissertation]. University of Alberta; 1990. Available from: https://era.library.ualberta.ca/files/8c97ks912

Durban University of Technology

22. Marsh-Brown, Scott. A comparative study with of the NMR spectra of Sulphur 12CH prepared using Hahnemannian method and sonication.

Degree: 2016, Durban University of Technology

URL: http://hdl.handle.net/10321/1556

►

Submitted in partial compliance with the requirements of the Master’s Degree in Technology: Homoeopathy, Durban University of Technology, Durban, South Africa, 2016.

Aim The aim… (more)

▼

Submitted in partial compliance with the requirements of the Master’s Degree in Technology: Homoeopathy, Durban University of Technology, Durban, South Africa, 2016.

Aim The aim of this study was to compare the nuclear magnetic resonance spectra of Sulphur 12c samples produced by the traditional Hahnemannian method with Sulphur 12c samples produced using sonication as an alternative method of agitation. Sonication, while not widely employed as an agitating technique in the homoeopathic potentisation process, is a highly effective agitation process which produces effects on liquids that closely resemble the effect of traditional Hahnemannian hand succussion (Bhattacharyya et al. 2008). Thus, this study sought to reveal whether or not homoeopathic remedies produced by sonication bore a close enough physicochemical resemblance to traditional hand succussed remedies to be considered as a viable equivalent. Methodology Five sample groups were manufactured for analysis, all by means of serial dilution at the centesimal ratio (1:100) to the 12c potency, and with agitation between dilution levels where applicable. Three of the sample groups were experimental, namely the Sulphur 12c Hahnemannian, Sulphur 12c sonicated and Sulphur 12c both (succussion and sonication). The Sulphur 12c Hahnemannian samples were produced by hand according to the German Homoeopathic Pharmacopoeia (Benyunes 2005), which includes an agitation phase of 10 hand succussions. Sonicated samples were produced according to the Hahnemannian method as far as possible, however the agitation phase consisted of 30 seconds of sonication in a sonication bath at 40Hz in accordance with related studies (Sukul, Sinhabau, and Sukul 1999: 58-59; Sukul et al. 2001a: 187). Sulphur 12c both (succussion and sonication) samples underwent ten hand succussions and 30 seconds of sonication at 40Hz between dilution levels. Two of the sample groups were controls, namely Sulphur 12c unagitated and Lactose 12c unagitated, neither of which underwent agitation between dilution phases but were otherwise produced according to the German Homoeopathic Pharmacopoeia specification (Benyunes 2005). All samples were raised to the 12c potency level in 87% alcohol from a 3CH triturate. The Lactose 12c unagitated control was derived from a 3CH triturate of lactose, while the other samples were all derived from a 3CH triturate of Sulphur. The sample groups were sent for nuclear magnetic resonance (NMR) spectroscopy at the Department of Chemistry at Stellenbosch University. The NMR device used was the Varian UnityInova 600 NMR Spectrometer ®, with a Deuterated DMSO insert added as an instrument frequency lock. Samples were drawn and analysed by Dr D.J. Brand. One sample was drawn from each sample group. The chemical shift and relative integration values for the OH, H2O, CH2, and CH3 peaks of the NMR spectra were captured and tabulated using Microsoft Excel© 2013. The statistical analysis was performed with the aid of SPSS Version 22. The chemical shift and relative…

Advisors/Committee Members: Ross, Ashley Hilton Adrian, Botha, Izel.

Subjects/Keywords: Homeopathy; Nuclear magnetic resonance spectroscopy; Sulfur – Spectra; Sonication

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Marsh-Brown, S. (2016). A comparative study with of the NMR spectra of Sulphur 12CH prepared using Hahnemannian method and sonication. (Thesis). Durban University of Technology. Retrieved from http://hdl.handle.net/10321/1556

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Marsh-Brown, Scott. “A comparative study with of the NMR spectra of Sulphur 12CH prepared using Hahnemannian method and sonication.” 2016. Thesis, Durban University of Technology. Accessed March 03, 2021. http://hdl.handle.net/10321/1556.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Marsh-Brown, Scott. “A comparative study with of the NMR spectra of Sulphur 12CH prepared using Hahnemannian method and sonication.” 2016. Web. 03 Mar 2021.

Vancouver:

Marsh-Brown S. A comparative study with of the NMR spectra of Sulphur 12CH prepared using Hahnemannian method and sonication. [Internet] [Thesis]. Durban University of Technology; 2016. [cited 2021 Mar 03]. Available from: http://hdl.handle.net/10321/1556.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Marsh-Brown S. A comparative study with of the NMR spectra of Sulphur 12CH prepared using Hahnemannian method and sonication. [Thesis]. Durban University of Technology; 2016. Available from: http://hdl.handle.net/10321/1556

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Loyola University Chicago

23. Liao, Shuyuan. Correlation of 17O Chemical Shifts of Chromium Carbene Complexes with Moss' Mxy Reacitvity Parameter.

Degree: MS, Chemistry, 1993, Loyola University Chicago

URL: https://ecommons.luc.edu/luc_theses/3958

Subjects/Keywords: Nuclear magnetic resonance spectroscopy.; Chemistry

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Liao, S. (1993). Correlation of 17O Chemical Shifts of Chromium Carbene Complexes with Moss' Mxy Reacitvity Parameter. (Thesis). Loyola University Chicago. Retrieved from https://ecommons.luc.edu/luc_theses/3958

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Liao, Shuyuan. “Correlation of 17O Chemical Shifts of Chromium Carbene Complexes with Moss' Mxy Reacitvity Parameter.” 1993. Thesis, Loyola University Chicago. Accessed March 03, 2021. https://ecommons.luc.edu/luc_theses/3958.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Liao, Shuyuan. “Correlation of 17O Chemical Shifts of Chromium Carbene Complexes with Moss' Mxy Reacitvity Parameter.” 1993. Web. 03 Mar 2021.

Vancouver:

Liao S. Correlation of 17O Chemical Shifts of Chromium Carbene Complexes with Moss' Mxy Reacitvity Parameter. [Internet] [Thesis]. Loyola University Chicago; 1993. [cited 2021 Mar 03]. Available from: https://ecommons.luc.edu/luc_theses/3958.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Liao S. Correlation of 17O Chemical Shifts of Chromium Carbene Complexes with Moss' Mxy Reacitvity Parameter. [Thesis]. Loyola University Chicago; 1993. Available from: https://ecommons.luc.edu/luc_theses/3958

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Stellenbosch University

24. Isingizwe Nturambirwe, Jean Frederic. Advances in spectral techniques for fruit quality evaluation: case of ULF-NMR and NIRS.

Degree: PhD, Electrical and Electronic Engineering, 2017, Stellenbosch University

URL: http://hdl.handle.net/10019.1/101155

► ENGLISH ABSTRACT: Industrial application of non-destructive analytical techniques still faces a challenge of lack of general and specialty models for quality evaluation. Current developments strive… (more)

▼ ENGLISH ABSTRACT: Industrial application of non-destructive analytical techniques still faces a challenge of lack of general and specialty models for quality evaluation. Current developments strive to alleviate this problem by the development of new cost effective equipment. In the food industry, and especially the horticultural industry, two spectroscopic methods seem to lead the way in terms of analytical variety, advancement in software for data handling and analysis, and relevance. The techniques in question are nuclear magnetic resonance (NMR) and near-infrared (NIR) spectroscopy. This project used practical experimental studies of fruit quality, using both techniques, to further research towards their non-destructive and online application, especially for horticultural products. A SQUID-NMR (Bm = 1Gauss) system was used to study the ripening of banana and predict its ripening index. Measurements of the NMR spin-lattice (T1) and the spin-spin (T2) relaxation times were acquired prior to destructive measurements. Various physico-chemical attributes were monitored for changes during the ripening process. Four out of six measurements, taken over a period of 10 days of storage (at 15 °C and 85%RH), were significantly different. Average T2 gave less promising results than average T1, that was highly correlated to attributes that changed during ripening, namely,lightness, L* (r=0.61), chromaticity coefficient, b* (r=0.65), totoal soluble solids, TSS (r= 0.72), sugar:acid ratio, TSS/TA (r=0.82), chromaticity coefficient, a* (r=0.84) and hue angle, h (r=-0.85). Correlations with T2 were found for TSS (r=-0.53), TSS/TA (-0.54) b* (-0.58) and pH (r=0.70), all significant at p<0.05. The ripening index was defined subjectively, based on the visual standards of the ripening index in banana. Average T1 distinctively explained the variance in ripening index, together with TSS, TSS/TA color parameters a* and h and total color difference. Calculation of the multicomponent distribution of T1 resulted in two components, one slow and another fast. Improvements in consistency of the transform is still required before it can be used for further analysis and accurate peak assignment. The results above show that there are opportunities of using SQUID detected NMR spectral data in the T1 domain for further studies of banana quality, and very likely other fruits as well. It is apparent that issues of temperature dependence of T1 should be taken into account in building more robust models. Fourier transform NIR (FT-NIR) was used in studying internal quality and mechanical damage in apples. Using three cultivars from two sources and three spectrometer modes from two FT-NIR spectrometers, we were able to account for the need of variability in building robust models. Different levels of predictability for each attribute were obtained for different cultivars, using PLS regression methods. The predictive ability was different between distinct spectral acquisition modes as well, but also depended on attributes. It was noticed… Advisors/Committee Members: Perold, Willem, Opara, Lionel, Stellenbosch University. Faculty of Engineering. Dept. of Electrical and Electronic Engineering..

Subjects/Keywords: UCTD; Nuclear magnetic resonance; Fruit – Quality; Near infrared spectroscopy

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Isingizwe Nturambirwe, J. F. (2017). Advances in spectral techniques for fruit quality evaluation: case of ULF-NMR and NIRS. (Doctoral Dissertation). Stellenbosch University. Retrieved from http://hdl.handle.net/10019.1/101155

Chicago Manual of Style (16^th Edition):

Isingizwe Nturambirwe, Jean Frederic. “Advances in spectral techniques for fruit quality evaluation: case of ULF-NMR and NIRS.” 2017. Doctoral Dissertation, Stellenbosch University. Accessed March 03, 2021. http://hdl.handle.net/10019.1/101155.

MLA Handbook (7^th Edition):

Isingizwe Nturambirwe, Jean Frederic. “Advances in spectral techniques for fruit quality evaluation: case of ULF-NMR and NIRS.” 2017. Web. 03 Mar 2021.

Vancouver:

Isingizwe Nturambirwe JF. Advances in spectral techniques for fruit quality evaluation: case of ULF-NMR and NIRS. [Internet] [Doctoral dissertation]. Stellenbosch University; 2017. [cited 2021 Mar 03]. Available from: http://hdl.handle.net/10019.1/101155.

Council of Science Editors:

Isingizwe Nturambirwe JF. Advances in spectral techniques for fruit quality evaluation: case of ULF-NMR and NIRS. [Doctoral Dissertation]. Stellenbosch University; 2017. Available from: http://hdl.handle.net/10019.1/101155

Stellenbosch University

25. Odendal, James Arthur. What is the possible origin of the 195Pt NMR shielding in the solid state? X-ray diffraction, solid-state NMR studies of deceptively simple C2[PtX6] salts (C = various cations, X = Cl- and Br-).

Degree: DSc, Chemistry and Polymer Science, 2015, Stellenbosch University

URL: http://hdl.handle.net/10019.1/96596

► ENGLISH ABSTRACT: The primary objective of the work presented in this thesis is to investigate the sensitivity and nature of the 195Pt chemical shift in… (more)

▼ ENGLISH ABSTRACT: The primary objective of the work presented in this thesis is to investigate the sensitivity and nature of the 195Pt chemical shift in the solid-state, as a function of temperature. We have carried out a series of experimental single crystal X-ray diffraction (SCXRD), solid state nuclear magnetic resonance (SSNMR) and density functional theory (DFT) experiments and calculations on various dication hexachloridoplatinate(IV) salts to paint a picture of the nature of the 195Pt shielding in the solid state. The results obtained from SCXRD analyses performed as a function of temperature on Rb2PtCl6, (NH4)2PtCl6 and [(N(CH3)4]2PtCl6 salts give a detailed account on the changing inter- and intramolecular interactions in dication hexachloridoplatinate(IV) salts upon lattice expansion, as a function of increasing temperature. The 195Pt SSNMR measurements of these salts have a peculiar 195Pt chemical shift sensitivity to changes in temperature. The 195Pt chemical shift trends performed as a function of temperature of the Rb2PtCl6 salt resulted in a linear-like trend with the slope of δ195Pt/T = 0.362 (0.008) ppm/K. The (NH4)2PtCl6 salt trend showed some non-linear characteristics at lower temperatures and tended towards linearity at a higher temperature with the slope δ195Pt/T = 0.228 (0.0126) ppm/K. The 195Pt chemical shift of the [(N(CH3)4]2PtCl6 had quite a different trend due to its well-known structural phase transitions as a function of temperature. The expected sensitivity range of the 195Pt chemical shift, predicted from experimental temperature dependent (100 K and 400 K) SCXRD measurements of Rb2PtCl6 and (NH4)2PtCl6 salts coincide well with that of experimental 195Pt chemical shift sensitivity. The atomic coordinates obtained from SCXRD analyses performed as a function of temperature were used to conduct DFT calculations to extract SSNMR parameters together with electrostatic potentials in order to study the local molecular and electronic structures of Rb2PtCl6 and (NH4)2PtCl6 salts. The computed 195Pt SSNMR parameters gave an account of chemical shift parameters and quadrupolar coupling parameters, which show excellent agreement with experimental 195Pt chemical shift SSNMR measurements. These calculations shed some light on the 35Cl SSNMR parameters, which to date are still unobtainable by means of conventional experimental SSNMR measurements. The computed 35Cl SSNMR shielding parameters showed that the electronic environments of the Cl- ion in dication hexachloridoplatinate(IV) salts are central to the understanding and interpretion of experimental 195Pt chemical shift sensitivity. These computational analyses gave the means to propose a theory whereby the : “polarization of electronic charge density from the PtIV ion towards the Cl- ion as the interaction between the anion and cation are being weakened due to lattice expansion as a function of increasing temperature”. This thesis shows that the combination of these three usually independently used analytical … Advisors/Committee Members: Koch, Klaus R., Barbour, Leonard J., Stellenbosch University. Faculty of Science. Dept. of Chemistry and Polymer Science..

Subjects/Keywords: UCTD; X-rays – Diffraction; Electronic structure – Salt; Nuclear magnetic resonance spectroscopy

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Odendal, J. A. (2015). What is the possible origin of the 195Pt NMR shielding in the solid state? X-ray diffraction, solid-state NMR studies of deceptively simple C2[PtX6] salts (C = various cations, X = Cl- and Br-). (Thesis). Stellenbosch University. Retrieved from http://hdl.handle.net/10019.1/96596

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Odendal, James Arthur. “What is the possible origin of the 195Pt NMR shielding in the solid state? X-ray diffraction, solid-state NMR studies of deceptively simple C2[PtX6] salts (C = various cations, X = Cl- and Br-).” 2015. Thesis, Stellenbosch University. Accessed March 03, 2021. http://hdl.handle.net/10019.1/96596.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Odendal, James Arthur. “What is the possible origin of the 195Pt NMR shielding in the solid state? X-ray diffraction, solid-state NMR studies of deceptively simple C2[PtX6] salts (C = various cations, X = Cl- and Br-).” 2015. Web. 03 Mar 2021.

Vancouver:

Odendal JA. What is the possible origin of the 195Pt NMR shielding in the solid state? X-ray diffraction, solid-state NMR studies of deceptively simple C2[PtX6] salts (C = various cations, X = Cl- and Br-). [Internet] [Thesis]. Stellenbosch University; 2015. [cited 2021 Mar 03]. Available from: http://hdl.handle.net/10019.1/96596.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Odendal JA. What is the possible origin of the 195Pt NMR shielding in the solid state? X-ray diffraction, solid-state NMR studies of deceptively simple C2[PtX6] salts (C = various cations, X = Cl- and Br-). [Thesis]. Stellenbosch University; 2015. Available from: http://hdl.handle.net/10019.1/96596

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Penn State University

26. Diehl, Brett Galen. Preparation and characterization of lignin-protein covalent linkages.

Degree: 2014, Penn State University

URL: https://submit-etda.libraries.psu.edu/catalog/21093

► Lignin is a natural aromatic polymer that is bio-synthesized in the cell walls of almost all land plants. Great strides have been made in understanding… (more)

▼ Lignin is a natural aromatic polymer that is bio-synthesized in the cell walls of almost all land plants. Great strides have been made in understanding lignin’s biological origins and chemical and physical properties. However, many unanswered questions remain. For example, the extent to which lignin interacts with other cell wall components, such as proteins, is largely unknown. In order to help address this question, the preparation and characterization of lignin-protein covalent linkages is reported here for the first time. Chapter 1 provides a more detailed introduction, justification, and literature review. Chapter 2 focuses on the preparation of low molecular weight lignin-protein model compounds. The compounds were not prepared under biomimetic conditions. Instead, the primary focus of this study was on the characterization of the model compounds, leading to the identification of diagnostic lignin-protein NMR chemical shifts. Chapter 3 describes the characterization of lignin-protein linkages prepared under biomimetic conditions of lignin DHP formation. NMR showed that cysteine and tyrosine containing peptides covalently crosslink with lignin, while other amino acids do not. IR and EDS were useful for showing the general incorporation of protein into the lignin, but were incapable of distinguishing covalent and non-covalent interactions. Chapter 4 describes the interaction between lignin and gelatin protein. It was found, using EDS and IR, that gelatin was incorporated into lignin DHP. However, a lack of diagnostic NMR signatures revealed that the crosslinking was likely dominated by non-covalent interactions such as physical entanglement. This seems likely, as gelatin is lacking in both cysteine and tyrosine residues, which were shown to be the only reactive amino acids towards lignin. Chapter 5 details attempts at identifying lignin-protein linkages in wild type Arabidopsis. Arabidopsis was grown to maturity, then lignin was extracted from cell wall material using acidified dioxane. Elemental analysis was used to show that the lignin was contaminated with about 3.75% protein; however, NMR was not able to identify lignin-protein covalent linkages. Chapter 6 details some future experiments that could be used to explore lignin-protein linkages, and it is hoped that this work will pave the way for such studies. Advisors/Committee Members: Nicole Robitaille Brown, Dissertation Advisor/Co-Advisor, Nicole Robitaille Brown, Committee Chair/Co-Chair, Jeffrey M Catchmark, Committee Member, John Edward Carlson, Committee Member, Dr. Emmanuel Hatzakis, Committee Member, Dr John Ralph, Special Member.

Subjects/Keywords: Lignin; protein; interactions; covalent crosslinking; nuclear magnetic resonance; infrared spectroscopy.

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Diehl, B. G. (2014). Preparation and characterization of lignin-protein covalent linkages. (Thesis). Penn State University. Retrieved from https://submit-etda.libraries.psu.edu/catalog/21093

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Diehl, Brett Galen. “Preparation and characterization of lignin-protein covalent linkages.” 2014. Thesis, Penn State University. Accessed March 03, 2021. https://submit-etda.libraries.psu.edu/catalog/21093.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Diehl, Brett Galen. “Preparation and characterization of lignin-protein covalent linkages.” 2014. Web. 03 Mar 2021.

Vancouver:

Diehl BG. Preparation and characterization of lignin-protein covalent linkages. [Internet] [Thesis]. Penn State University; 2014. [cited 2021 Mar 03]. Available from: https://submit-etda.libraries.psu.edu/catalog/21093.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Diehl BG. Preparation and characterization of lignin-protein covalent linkages. [Thesis]. Penn State University; 2014. Available from: https://submit-etda.libraries.psu.edu/catalog/21093

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Victoria University of Wellington

27. Anjum, Muhammad Ali Raza. High-resolution multidimensional parametric estimation for nuclear magnetic resonance spectroscopy.

Degree: 2019, Victoria University of Wellington

URL: http://hdl.handle.net/10063/8149

► Nuclear Magnetic Resonance spectroscopy (NMR) is a powerful technique for rapid and efficient quantitation of compounds in chemical samples. NMR causes the nuclei in the… (more)

▼ Nuclear Magnetic Resonance spectroscopy (NMR) is a powerful technique for rapid and efficient quantitation of compounds in chemical samples. NMR causes the nuclei in the molecules to resonate and various chemical arrangements appear as peaks in the Fourier spectrum of a free induction decay (FID). The spectral parameters elicited from the peaks serve as a fingerprint of the chemical components contained in the molecule. These fingerprints can be employed to understand the chemical structure. Signal acquired from a NMR spectrometer is ideally modelled as a superposition of multiple damped complex exponentials (cisoids) in Additive White Gaussian Noise (AWGN). The number as well as the spectral parameters of the cisoids need to be estimated for characterisation of the underlying chemicals. The estimation, however, suffers from numerous difficulties in practice. These include: unknown number of cisoids, large signal length, large dynamic range, large peak density, and numerous distortions caused by experimental artefacts. This thesis aims at the development of estimators that, in view of the above-mentioned practical features, are capable of rapid, high-resolution and apriori-information-free quantitation of NMR signals. Moreover, for the analytic evaluation of the performance of such estimators, the thesis aims to derive interpretable analytic results for the fundamental estimation theory tool for assessing the performance of an unbiased estimator: the Cramer Rao Lower Bound (CRLB). By such results, we mean those that analytically allow the determination, in terms of the CRLB, of the impact of the free model parameters on the estimator performance. For the CRLB, we report analytic expressions on the variance of unbiased parameter estimates of damping factors, frequencies and complex amplitudes of an arbitrary number of damped cisoids embedded in AWGN. In addition to the CRLB, analytic expressions for the determinant and the condition number of the associated Fisher Information Matrix (FIM) are also reported. Further results, in similar order, are reported for two special cases of the damped cisosid model: the Magnetic Resonance Relaxometry model and the amplitude-only model (employed in quantitative NMR - qNMR). Some auxiliary results for the above-mentioned models are also presented, i.e., on the multiplicity of the eigenvalues and the factorisation of the characteristic polynomial associated with their respective FIMs. These results have not been previously reported. The reported theoretical results successfully account for various physical and chemical phenomena observed in experimental NMR data, and quantify their impact on the accuracy of an unbiased estimator as a function of both model and experimental parameters, e.g., influence of prior knowledge, peak multiplicity, multiplet symmetry, solvent peak, carbon satellites, etc. For rapid, high-resolution and apriori-information-free quantitation of NMR signals, a sub-band Steiglitz-McBride algorithm is reported. The developed algorithm directly converts the… Advisors/Committee Members: Teal, Paul, Dmochowski, Pawel.

Subjects/Keywords: Nuclear Magnetic Resonance; Spectroscopy; Parametric estimation; NMR; MRS; Parametric; Estimation

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Anjum, M. A. R. (2019). High-resolution multidimensional parametric estimation for nuclear magnetic resonance spectroscopy. (Doctoral Dissertation). Victoria University of Wellington. Retrieved from http://hdl.handle.net/10063/8149

Chicago Manual of Style (16^th Edition):

Anjum, Muhammad Ali Raza. “High-resolution multidimensional parametric estimation for nuclear magnetic resonance spectroscopy.” 2019. Doctoral Dissertation, Victoria University of Wellington. Accessed March 03, 2021. http://hdl.handle.net/10063/8149.

MLA Handbook (7^th Edition):

Anjum, Muhammad Ali Raza. “High-resolution multidimensional parametric estimation for nuclear magnetic resonance spectroscopy.” 2019. Web. 03 Mar 2021.

Vancouver:

Anjum MAR. High-resolution multidimensional parametric estimation for nuclear magnetic resonance spectroscopy. [Internet] [Doctoral dissertation]. Victoria University of Wellington; 2019. [cited 2021 Mar 03]. Available from: http://hdl.handle.net/10063/8149.

Council of Science Editors:

Anjum MAR. High-resolution multidimensional parametric estimation for nuclear magnetic resonance spectroscopy. [Doctoral Dissertation]. Victoria University of Wellington; 2019. Available from: http://hdl.handle.net/10063/8149

Oregon State University

28. Williamson, R. Thomas. Development and application of NMR spectroscopy to marine natural products structure and biosynthesis.

Degree: PhD, Pharmacy, 2000, Oregon State University

URL: http://hdl.handle.net/1957/32846

Subjects/Keywords: Nuclear magnetic resonance spectroscopy

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Williamson, R. T. (2000). Development and application of NMR spectroscopy to marine natural products structure and biosynthesis. (Doctoral Dissertation). Oregon State University. Retrieved from http://hdl.handle.net/1957/32846

Chicago Manual of Style (16^th Edition):

Williamson, R Thomas. “Development and application of NMR spectroscopy to marine natural products structure and biosynthesis.” 2000. Doctoral Dissertation, Oregon State University. Accessed March 03, 2021. http://hdl.handle.net/1957/32846.

MLA Handbook (7^th Edition):

Williamson, R Thomas. “Development and application of NMR spectroscopy to marine natural products structure and biosynthesis.” 2000. Web. 03 Mar 2021.

Vancouver:

Williamson RT. Development and application of NMR spectroscopy to marine natural products structure and biosynthesis. [Internet] [Doctoral dissertation]. Oregon State University; 2000. [cited 2021 Mar 03]. Available from: http://hdl.handle.net/1957/32846.

Council of Science Editors:

Williamson RT. Development and application of NMR spectroscopy to marine natural products structure and biosynthesis. [Doctoral Dissertation]. Oregon State University; 2000. Available from: http://hdl.handle.net/1957/32846

Oregon State University

29. Mullen, Corina P. High-temperature, high-pressure NMR probe for superconducting magnets.

Degree: MS, Physics, 1996, Oregon State University

URL: http://hdl.handle.net/1957/34276

► A high-temperature, high-pressure autoclave has been adapted for use with a high-field nuclear magnetic resonance spectrometer. The autoclave has an internal pressure range of atmospheric… (more)

Subjects/Keywords: Nuclear magnetic resonance spectroscopy

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Mullen, C. P. (1996). High-temperature, high-pressure NMR probe for superconducting magnets. (Masters Thesis). Oregon State University. Retrieved from http://hdl.handle.net/1957/34276

Chicago Manual of Style (16^th Edition):

Mullen, Corina P. “High-temperature, high-pressure NMR probe for superconducting magnets.” 1996. Masters Thesis, Oregon State University. Accessed March 03, 2021. http://hdl.handle.net/1957/34276.

MLA Handbook (7^th Edition):

Mullen, Corina P. “High-temperature, high-pressure NMR probe for superconducting magnets.” 1996. Web. 03 Mar 2021.

Vancouver:

Mullen CP. High-temperature, high-pressure NMR probe for superconducting magnets. [Internet] [Masters thesis]. Oregon State University; 1996. [cited 2021 Mar 03]. Available from: http://hdl.handle.net/1957/34276.

Council of Science Editors:

Mullen CP. High-temperature, high-pressure NMR probe for superconducting magnets. [Masters Thesis]. Oregon State University; 1996. Available from: http://hdl.handle.net/1957/34276

University of Delaware

30. Ongagna Yhombi, Yvon Serge. Molecular mechanisms of the salt tolerance response in the halophile Vibrio parahaemolyticus.

Degree: PhD, University of Delaware, Department of Biological Sciences, 2014, University of Delaware

URL: http://udspace.udel.edu/handle/19716/13410

► In order to investigate the functionality of specialized genomic features in the osmotic stress tolerance of Vibrio parahaemolyticus , we divided the research project in… (more)

▼ In order to investigate the functionality of specialized genomic features in the osmotic stress tolerance of Vibrio parahaemolyticus , we divided the research project in three parts: (1) Examine the role of the ectoine and glycine betaine biosynthesis systems in the NaCl stress response, (2) Determine the role of the four putative Betaine Carnitine Choline transporter (BCCT) homologues in the NaCl stress response, and (3) Determine the role of two ProXWV (ProU1 and ProU2) homologues in the NaCl stress response. The role of the two synthesis systems in the NaCl stress response. We demonstrated that V. parahaemolyticus had an extended salt tolerance range up to 10.5% NaCl in complex media and a 6% NaCl tolerance in defined M9 minimal media. We demonstrated that exogenously supplied compatible solutes or their precursors in defined media relieved the growth constraint caused by high NaCl. By using proton Nuclear Magnetic Resonance spectroscopy (1 HNMR) analysis, we determined for the first time the profile of compatible solutes synthesized and accumulated by this organism. Furthermore, we showed that V. parahaemolyticus cells could perform de novo synthesis of ectoine and glutamate in a NaCl dependent manner. By comparative growth analysis in defined media amended to high osmolarity containing exogenously supplied compatible solutes or their precursors, we ranked the most effective compatible solutes in V. parahaemolyticus in the following order: glycine betaine, choline, proline, glutamate, and ectoine. Interestingly, we showed that V. parahaemolyticus could use glutamate or proline as a sole carbon source, but not ectoine and glycine betaine. By expression analysis of the ectoine (ectA ) and glycine betaine ( betA ) biosynthesis genes we determined that both systems were constitutively expressed at a basal level, but upregulated upon NaCl upshock. To examine the essentiality of the biosynthesis systems in V. parahaemolyticus at high osmolarity, comparative growth analysis was performed between V. parahaemolyticus wild type (WT) and mutants harboring deletion mutations in the betaine synthesis (Δ betA ), the ectoine synthesis (ΔectB ), and both systems (ΔbetAectB ). Growth in media of high osmolarity lacking compatible solutes revealed that Δ ectB and deltabetAectB mutant strains were defective compared to the WT and ΔbetA mutant. Furthermore, this result indicated that the ectoine synthesis was critical for growth at high osmolarity. Interestingly, the ΔbetA mutant strain could not grow in high osmolarity media supplied with choline. Irrespective of the mutant strains, growth at high osmolarity was rescued to the wild type level in the presence of glycine betaine. Finally, we performed a phylogenetic survey of the synthesis systems among the members of the genus Vibrio and showed the predominance of both systems in these species. The role of the four putative BCCT homologues in the NaCl stress response. To test the hypothesis that the four Betaine Carnitine Choline Transporters (BCCTs) are functional, we… Advisors/Committee Members: Boyd, E. Fidelma.

Subjects/Keywords: Vibrio parahaemolyticus.; Genomics.; Salt.; Osmosis.; Nuclear magnetic resonance spectroscopy.

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Ongagna Yhombi, Y. S. (2014). Molecular mechanisms of the salt tolerance response in the halophile Vibrio parahaemolyticus. (Doctoral Dissertation). University of Delaware. Retrieved from http://udspace.udel.edu/handle/19716/13410

Chicago Manual of Style (16^th Edition):

Ongagna Yhombi, Yvon Serge. “Molecular mechanisms of the salt tolerance response in the halophile Vibrio parahaemolyticus.” 2014. Doctoral Dissertation, University of Delaware. Accessed March 03, 2021. http://udspace.udel.edu/handle/19716/13410.

MLA Handbook (7^th Edition):

Ongagna Yhombi, Yvon Serge. “Molecular mechanisms of the salt tolerance response in the halophile Vibrio parahaemolyticus.” 2014. Web. 03 Mar 2021.

Vancouver:

Ongagna Yhombi YS. Molecular mechanisms of the salt tolerance response in the halophile Vibrio parahaemolyticus. [Internet] [Doctoral dissertation]. University of Delaware; 2014. [cited 2021 Mar 03]. Available from: http://udspace.udel.edu/handle/19716/13410.

Council of Science Editors:

Ongagna Yhombi YS. Molecular mechanisms of the salt tolerance response in the halophile Vibrio parahaemolyticus. [Doctoral Dissertation]. University of Delaware; 2014. Available from: http://udspace.udel.edu/handle/19716/13410

Open Access Theses and Dissertations