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1.
Aras, E. Sümer (Danışman).
Soğuk stresi altında geliştirilmiş ayçiçeği (Helianthus annuus l.) bitkisinde bZIP, MYB, NAC, NF-YB ve WRKY tipi transkripsiyon faktör genlerinin mRNA ifade seviyelerinin belirlenmesi.
Degree: 2018, University of Ankara
URL: http://hdl.handle.net/20.500.12575/42003
► Soğuk stresi, bitkilerin tarımsal verimliliğini sınırlayan en önemli çevresel faktörlerden biridir. Soğuk stresi, ciddi membran hasarına neden olabilir. Membran hasarı, soğuk yanıtında görev alan genlerin…
(more)
▼ Soğuk stresi, bitkilerin tarımsal verimliliğini sınırlayan en önemli çevresel faktörlerden
biridir. Soğuk stresi, ciddi membran hasarına neden olabilir. Membran hasarı, soğuk
yanıtında görev alan genlerin ve transkripsiyon faktörlerinin stres toleransına aracılık
etmesi için bir sinyal oluşturur. bZIP, MYB,
NAC, NF-YB ve WRKY transkripsiyon
faktörü aileleri abiyotik ve biyotik stres faktörlerine karşı bitki yanıtlarında önemli
roller oynamaktadır. Bu çalışmada, bu transkripsiyon faktör ailesi genlerinin mRNA
ifade düzeyleri, ayçiçeğinde soğuk stresine karşı potansiyel işlevlerini araştırmak için
ilk kez çalışılmıştır. Ayçiçeği fideleri (15 günlük) çeĢitli zaman aralıklarında (0, 2g, 4g,
6g, 8g, 10g) bitki büyütme kabininde 4 °C‟de inkübe edilerek soğuk stresine maruz
bırakılmıştır. Yaprak ve köklerde soğuk stresinin bZIP, MYB,
NAC, NF-YB ve WRKY
genlerinin ifade profili üzerindeki etkilerini anlamak için kantitatif gerçek zamanlı PZR
yapılmıştır. Ayrıca, yapraklarda ve köklerde malondialdehit (MDA) ve toplam
çözünebilir protein içerikleri tespit edilmiştir. Yapılan analizler sonucunda çalışmada
kullanılan ayçiçeği çeşitleri arasında Tr-3080 çeşidinin daha duyarlı, Tarsan 1018
çeşidinin ise soğuk stres koşullarına karşı diğerlerine göre daha dirençli olduğu
belirlenmiştir. Elde edilen tüm moleküler veriler birlikte değerlendirildiğinde bZIP,
MYB,
NAC, NF-YB ve WRKY genlerinin soğuk ile indüklendiği ve soğuk stresine
yanıtta rol alabileceği söylenebilir. Ayrıca bu çalışmadan elde edilen verilerin soğuk
stresine dayanıklı ayçiçeği çeşitlerinin elde edilmesine yönelik daha ileriki çalışmalara
da katkı sağlayacağı düşünülmektedir.
Cold stress is one of the most important environmental factors that limits the
agricultural productivity of plants. Cold stress can cause serious membrane damage.
Membrane damage leads to a signal for cold-responsive genes and transcription factors
to mediate stress tolerance. bZIP, MYB,
NAC, NF-YB and WRKY transcription factors
families play important roles in plant responses to abiotic and biotic stresses. In this
study, mRNA expression levels of this transcription factor family genes were
investigated for the first time, to investigate their potential functions in response to cold
stress in sunflower. Plants (15-day-old) were subjected to cold stress by incubating at
4°C in plant growth cabinet for in various time intervals (0, 2d, 4d, 6d, 8d, 10d). To
understand the effects of cold stress on expression profile of bZIP, MYB,
NAC, NF-YB
and WRKY genes in leaves and roots, quantitative real time PCR was performed. In
addition, malondialdehyde (MDA) and total soluble protein contents in the leaves and
the roots were detected. All results showed that among the varieties of sunflower used
in the study, Tr-3080 species was more sensitive species, whereas Tarsan 1018 variety
was more resistant to cold stress conditions than the others. When all of the molecular
data obtained from this study are evaluated together, we can say that bZIP, MYB,
NAC,
NF-YB and WRKY…
Advisors/Committee Members: Aras, E. Sümer (advisor).
Subjects/Keywords: Helianthus annuus L; bZIP; MYB; NAC; NF-YB
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APA ·
Chicago ·
MLA ·
Vancouver ·
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APA (6th Edition):
Aras, E. S. (. (2018). Soğuk stresi altında geliştirilmiş ayçiçeği (Helianthus annuus l.) bitkisinde bZIP, MYB, NAC, NF-YB ve WRKY tipi transkripsiyon faktör genlerinin mRNA ifade seviyelerinin belirlenmesi. (Thesis). University of Ankara. Retrieved from http://hdl.handle.net/20.500.12575/42003
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Aras, E Sümer (Danışman). “Soğuk stresi altında geliştirilmiş ayçiçeği (Helianthus annuus l.) bitkisinde bZIP, MYB, NAC, NF-YB ve WRKY tipi transkripsiyon faktör genlerinin mRNA ifade seviyelerinin belirlenmesi.” 2018. Thesis, University of Ankara. Accessed January 22, 2021.
http://hdl.handle.net/20.500.12575/42003.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Aras, E Sümer (Danışman). “Soğuk stresi altında geliştirilmiş ayçiçeği (Helianthus annuus l.) bitkisinde bZIP, MYB, NAC, NF-YB ve WRKY tipi transkripsiyon faktör genlerinin mRNA ifade seviyelerinin belirlenmesi.” 2018. Web. 22 Jan 2021.
Vancouver:
Aras ES(. Soğuk stresi altında geliştirilmiş ayçiçeği (Helianthus annuus l.) bitkisinde bZIP, MYB, NAC, NF-YB ve WRKY tipi transkripsiyon faktör genlerinin mRNA ifade seviyelerinin belirlenmesi. [Internet] [Thesis]. University of Ankara; 2018. [cited 2021 Jan 22].
Available from: http://hdl.handle.net/20.500.12575/42003.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Aras ES(. Soğuk stresi altında geliştirilmiş ayçiçeği (Helianthus annuus l.) bitkisinde bZIP, MYB, NAC, NF-YB ve WRKY tipi transkripsiyon faktör genlerinin mRNA ifade seviyelerinin belirlenmesi. [Thesis]. University of Ankara; 2018. Available from: http://hdl.handle.net/20.500.12575/42003
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Virginia Commonwealth University
2.
Moore, Thomas B.
The Role of N-acetyl-L-Cysteine (NAC) as an Adjuvant to Opioid Treatment in Patients with Inadequately Controlled Chronic Neuropathic Pain.
Degree: PhD, Psychology, 2016, Virginia Commonwealth University
URL: https://doi.org/10.25772/P1Z0-JA31
;
https://scholarscompass.vcu.edu/etd/4315
► Introduction. While opioid medications are commonly prescribed for management of neuropathic pain (NP), long-term use has been associated with increased risk for overdose, drug…
(more)
▼ Introduction. While opioid medications are commonly prescribed for management of neuropathic pain (NP), long-term use has been associated with increased risk for overdose, drug interactions and addiction. New strategies are necessary to better manage chronic pain, thereby reducing need for opioid medications and their associated adverse consequences. N-acetyl-
L-cysteine (
NAC), an over-the-counter supplement, has shown promise in the treatment of psychiatric and addictive disorders. In addition,
NAC has shown promise for reducing physiological signs of NP in laboratory rat models, prompting this study.
Purpose. The present study was an open-label clinical trial of
NAC as an adjuvant to opioid treatment for poorly controlled, chronic NP. It examined whether 1200 mg
NAC twice daily for 4 weeks was associated with: lower ratings of patient-reported pain; reductions in PRN opioid medication for breakthrough pain; and improvements in physical and mental health quality of life (QoL). The study also examined whether appraisal of pain impacts response to medication.
Method. Participants were N=28 chronic NP patients who consented to study participation. This consisted of 2 baseline assessments, 4 weeks of
NAC and 1 post-trial follow-up visit. The majority (N=17) dropped out or were excluded during baseline. Of the remaining participants, N = 11 started the study medication and N=10 completed the study, with daily recordings of pain severity ratings and use of PRN opioid medication. Small sample size limited analyses to qualitative case reviews and effect sizes.
Results. Over 90% of participants receiving
NAC completed the study. Case review found varied results. While 4 of 10 participants showed decrease in average pain ratings during
NAC, estimated effect sizes for the whole sample were small, bordering on negligible (ω² from .003 to .027) as were those for PRN opioids (Partial Eta-Squared=.0003). Effect size for mental health QoL was medium (Cohen's
d=.421).
Conclusions. With N=10, findings must be interpreted with caution. Nonetheless, the study found some albeit small evidence supporting
NAC for improving mental health QoL and pain ratings. Several participants reported improvements in pain and mental health domains while taking
NAC.
NAC was well tolerated with minimal side effects. Lessons from this study will inform design and implementation of future
NAC studies.
Advisors/Committee Members: Dace Svikis, James P. McCullough, Pamela Dillon, Lisa Phipps, Micheal Weaver.
Subjects/Keywords: N-acetyl-L-Cysteine; NAC; Chronic Neuropathic Pain; opioid treatment; open-label trial; Clinical Psychology; Health Psychology; Pain Management
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Moore, T. B. (2016). The Role of N-acetyl-L-Cysteine (NAC) as an Adjuvant to Opioid Treatment in Patients with Inadequately Controlled Chronic Neuropathic Pain. (Doctoral Dissertation). Virginia Commonwealth University. Retrieved from https://doi.org/10.25772/P1Z0-JA31 ; https://scholarscompass.vcu.edu/etd/4315
Chicago Manual of Style (16th Edition):
Moore, Thomas B. “The Role of N-acetyl-L-Cysteine (NAC) as an Adjuvant to Opioid Treatment in Patients with Inadequately Controlled Chronic Neuropathic Pain.” 2016. Doctoral Dissertation, Virginia Commonwealth University. Accessed January 22, 2021.
https://doi.org/10.25772/P1Z0-JA31 ; https://scholarscompass.vcu.edu/etd/4315.
MLA Handbook (7th Edition):
Moore, Thomas B. “The Role of N-acetyl-L-Cysteine (NAC) as an Adjuvant to Opioid Treatment in Patients with Inadequately Controlled Chronic Neuropathic Pain.” 2016. Web. 22 Jan 2021.
Vancouver:
Moore TB. The Role of N-acetyl-L-Cysteine (NAC) as an Adjuvant to Opioid Treatment in Patients with Inadequately Controlled Chronic Neuropathic Pain. [Internet] [Doctoral dissertation]. Virginia Commonwealth University; 2016. [cited 2021 Jan 22].
Available from: https://doi.org/10.25772/P1Z0-JA31 ; https://scholarscompass.vcu.edu/etd/4315.
Council of Science Editors:
Moore TB. The Role of N-acetyl-L-Cysteine (NAC) as an Adjuvant to Opioid Treatment in Patients with Inadequately Controlled Chronic Neuropathic Pain. [Doctoral Dissertation]. Virginia Commonwealth University; 2016. Available from: https://doi.org/10.25772/P1Z0-JA31 ; https://scholarscompass.vcu.edu/etd/4315
3.
Mayra Juline GonÃalves.
Characterization of combinations of cup and rootstok of european pear cultivars as aâentomosporioseâ leaf spot and indexes the necrosis in flower bud abortiom in Santa Catarina State.
Degree: 2012, Universidade do Estado de Santa Catarina
URL: http://www.tede.udesc.br/tde_busca/arquivo.php?codArquivo=3147
► Este trabalho objetivou avaliar a dinÃmica temporal da Entomosporiose em diferentes combinaÃÃes de cultivares copa pereira europeia (Rocha, Abate Fetel e Santa Maria) sobre diferentes…
(more)
▼ Este trabalho objetivou avaliar a dinÃmica temporal da Entomosporiose em diferentes combinaÃÃes de cultivares copa pereira europeia (Rocha, Abate Fetel e Santa Maria) sobre diferentes portaenxertos (Marmelo A e Marmelo Adams) e avaliar a etiologia e a evoluÃÃo da necrose de gemas florais em combinaÃÃes de cultivares copa (ClappÂsFavorite, PackhamÂsTriumph, Conference, Williamâs, Rocha, Abate Fetel, Santa Maria, Decana) de pereira europeia sobre diferentes portaenxertos (Marmelo A, Marmelo C e Marmelo Adams) nas condiÃÃes edafoclimÃticas do estado de Santa Catarina. Na Entomosporiose a incidÃncia e a severidade foram avaliadas semanalmente ao surgimento dos primeiros sintomas em 100 folhas aleatÃrias, distribuÃdas em 4 ramos medianos por planta. A incidÃncia foi calculada pela percentagem das folhas com pelo menos uma lesÃo em relaÃÃo ao nÃmero total de folhas avaliadas e a severidade atravÃs de classes de infecÃÃo. Os experimentos de necrose foram conduzidos em pomares comerciais nos municÃpios de Fraiburgo e Urupema durante as safras 2009/10 e 2010/11. No perÃodo de junho a setembro foram coletas 10 gemas de cada combinaÃÃo e Ãrea experimental, nos estÃdios fenolÃgicos de repouso vegetativo e abertura das escamas, e avaliadas quanto a presenÃa de necrose. As gemas foram incubadas em meios de cultura especÃfico para fungos (BDA) e para bactÃrias (B de King). A identificaÃÃo fÃngica foi realizada atravÃs da visualizaÃÃo das estruturas reprodutivas e chaves de identificaÃÃo. Para identificaÃÃo bacteriana, culturas puras foram caraterizadas atravÃs do LOPAT segundo a descriÃÃo de Shaad (2001). A presenÃa ou nÃo de necrose de gemas foram correlacionadas com as combinaÃÃes de cultivares e portaenxertos, estÃdio fenolÃgicos e agente causal. Com os dados de incidÃncia e severidade da Entomosporiose foram plotadas curvas de progresso da doenÃa e as epidemias comparadas em relaÃÃo a: a) inÃcio do aparecimento dos sintomas (IAS); b) tempo para atingir a mÃxima incidÃncia e severidade da doenÃa (TAMID e TAMSD); c) valor mÃximo de incidÃncia e severidade (Imax e Smax) e d) Ãrea abaixo da curva do progresso da incidÃncia e da severidade da doenÃa (AACPID e AACPSD). Nas gemas necrosadas, verificou-se a presenÃa das bactÃrias Pseudomonas syringae do gÃnero e Xanthomonas e nÃo houve diferenÃas significativas na ocorrÃncia de necrose das gemas tanto nas combinaÃÃes de cultivares e portaenxerto quanto nos estÃdios fenolÃgicos avaliados. As bactÃrias identificadas estÃo envolvidas na necrose de gemas florais de pereira europeia como um fator indutor secundÃrio. Todas as combinaÃÃes de cultivares e portaenxertos foram suscetÃveis a Entomosporium mespili e a maior intensidade de doenÃa ocorreu na cultivar Santa Maria, independente do portaenxerto utilizado. Houve diferenÃa significativa nas curvas de progresso da doenÃa tanto da incidÃncia quanto da severidade da Entomosporiose nas cultivares Rocha, Abate Fetel e Santa Maria
Advisors/Committee Members: Amauri Bogo.
Subjects/Keywords: entomosporium mespili; . pyrus communis l.; AGRONOMIA; pyrus communis l.; necrose floral; pseudomonas sp.; buds death; xanthomonas sp.; epidemiologia; entomosporium mespil; pseudomonas sp.; xanthomonas sp.; epidemiology
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
GonÃalves, M. J. (2012). Characterization of combinations of cup and rootstok of european pear cultivars as aâentomosporioseâ leaf spot and indexes the necrosis in flower bud abortiom in Santa Catarina State. (Thesis). Universidade do Estado de Santa Catarina. Retrieved from http://www.tede.udesc.br/tde_busca/arquivo.php?codArquivo=3147
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
GonÃalves, Mayra Juline. “Characterization of combinations of cup and rootstok of european pear cultivars as aâentomosporioseâ leaf spot and indexes the necrosis in flower bud abortiom in Santa Catarina State.” 2012. Thesis, Universidade do Estado de Santa Catarina. Accessed January 22, 2021.
http://www.tede.udesc.br/tde_busca/arquivo.php?codArquivo=3147.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
GonÃalves, Mayra Juline. “Characterization of combinations of cup and rootstok of european pear cultivars as aâentomosporioseâ leaf spot and indexes the necrosis in flower bud abortiom in Santa Catarina State.” 2012. Web. 22 Jan 2021.
Vancouver:
GonÃalves MJ. Characterization of combinations of cup and rootstok of european pear cultivars as aâentomosporioseâ leaf spot and indexes the necrosis in flower bud abortiom in Santa Catarina State. [Internet] [Thesis]. Universidade do Estado de Santa Catarina; 2012. [cited 2021 Jan 22].
Available from: http://www.tede.udesc.br/tde_busca/arquivo.php?codArquivo=3147.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
GonÃalves MJ. Characterization of combinations of cup and rootstok of european pear cultivars as aâentomosporioseâ leaf spot and indexes the necrosis in flower bud abortiom in Santa Catarina State. [Thesis]. Universidade do Estado de Santa Catarina; 2012. Available from: http://www.tede.udesc.br/tde_busca/arquivo.php?codArquivo=3147
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Vytautas Magnus University
4.
Staradumskytė,
Daiva.
Geltonkaklių pelių (Apodemus flavicollis)
genetinis kintamumas ir užsikrėtimas Anaplasma sp. ir Borrelia
burgdorferi s.l.
Degree: Master, Biology, 2010, Vytautas Magnus University
URL: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2010~D_20100614_093721-35395
;
► Naudojant atsitiktinai amplifikuotos polimorfinės DNR ir polimerazinės grandinės reakcijos (AAPD - PGR) metodą įvertintas genetinis kintamumas Apodemus flavicollis iš dvylikos skirtingų populiacijų esančių keturiose Europos…
(more)
▼ Naudojant atsitiktinai amplifikuotos
polimorfinės DNR ir polimerazinės grandinės reakcijos (AAPD - PGR)
metodą įvertintas genetinis kintamumas Apodemus flavicollis iš
dvylikos skirtingų populiacijų esančių keturiose Europos šalyse
(Norvegija, Suomija, Latvija, Lietuva). Iš dešimties
oligonukleotidinių pradmenų (ROTH – 180 -01, ROTH – 180 – 02, ROTH
– 180 – 03, ROTH – 180 – 04, ROTH – 180 – 05, ROTH – 180 – 06, ROTH
– 180 – 07, ROTH – 180 – 08, ROTH – 180 – 09, ROTH – 180 – 10) šeši
buvo tinkami tirtos rūšies populiacinei analizei. Elektroforezės
metu buvo nustatyti 180 skirtingų fragmentų. Duomenų analizė buvo
atlikta su PopGene3.2, TREECON kompiuterinėmis programomis. Buvo
apskaičiuoti populiacijų DNR polimorfizmai, polimorfinių lokusų
skaičius. Nubraižytos filogenetinių ryšių dendogramos.
Pasinaudojant polimerazine grandinine reakcija buvo patikrintas
graužikų užsikrėtimas B. burgdorferi s. l. ir Anaplasma sp.trijose
populiacijose (Ombo, Tromoya, Tuja).
DNA polymorphism were analyzed by a randomly
amplified polymorphic DNA polymerase chain reaction (RAPD - PCR)
technique studied in 209 specimens of Apodemus flavicollis from
twelve different populations from four different countries of
Europe (Norway, Finland, Latvia, Lithuania) using ten primers (ROTH
– 180 -01, ROTH – 180 – 02, ROTH – 180 – 03, ROTH – 180 – 04, ROTH
– 180 – 05, ROTH – 180 – 06, ROTH – 180 – 07, ROTH – 180 – 08, ROTH
– 180 – 09, ROTH – 180 – 10) six of them gave specific patterns and
could be used as genetic markers for the species analyzed. Visual
examination of electrophoresis gels showed that the number af
polymorphic loci are 180. PopGene3.2, TREECON was used for the
estimation of genetic variability, DNA polimorfism, polimorfic
locus. Were painted phylogenetic trees of populations. Using PCR
mice infestation of B. burgdorferi s. l. and Anaplasma sp were
analyzed from 3 populations (Tromoya, Ombo,
Tuja).
Advisors/Committee Members: Tubelytė, Vaida (Master’s degree session secretary), Rugienius, Rytis (Master’s degree committee chair), Radzijevskaja, Jana (Master’s degree committee member), Sruoga, Aniolas (Master’s thesis reviewer), Ambrasienė, Daiva (Master’s degree committee member), Paulauskas, Algimantas (Master’s thesis supervisor).
Subjects/Keywords: AAPD; PGR; Geltonkaklė
pelė; Anaplasma sp; B. burgdorferi s.
l; RAPD; PCR; Yellow-necked
mouse; Anaplasma sp; B. burgdorferi s.
l
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Record Details
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Staradumskytė,
Daiva. (2010). Geltonkaklių pelių (Apodemus flavicollis)
genetinis kintamumas ir užsikrėtimas Anaplasma sp. ir Borrelia
burgdorferi s.l. (Masters Thesis). Vytautas Magnus University. Retrieved from http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2010~D_20100614_093721-35395 ;
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
Chicago Manual of Style (16th Edition):
Staradumskytė,
Daiva. “Geltonkaklių pelių (Apodemus flavicollis)
genetinis kintamumas ir užsikrėtimas Anaplasma sp. ir Borrelia
burgdorferi s.l.” 2010. Masters Thesis, Vytautas Magnus University. Accessed January 22, 2021.
http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2010~D_20100614_093721-35395 ;.
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
MLA Handbook (7th Edition):
Staradumskytė,
Daiva. “Geltonkaklių pelių (Apodemus flavicollis)
genetinis kintamumas ir užsikrėtimas Anaplasma sp. ir Borrelia
burgdorferi s.l.” 2010. Web. 22 Jan 2021.
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
Vancouver:
Staradumskytė,
Daiva. Geltonkaklių pelių (Apodemus flavicollis)
genetinis kintamumas ir užsikrėtimas Anaplasma sp. ir Borrelia
burgdorferi s.l. [Internet] [Masters thesis]. Vytautas Magnus University; 2010. [cited 2021 Jan 22].
Available from: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2010~D_20100614_093721-35395 ;.
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
Council of Science Editors:
Staradumskytė,
Daiva. Geltonkaklių pelių (Apodemus flavicollis)
genetinis kintamumas ir užsikrėtimas Anaplasma sp. ir Borrelia
burgdorferi s.l. [Masters Thesis]. Vytautas Magnus University; 2010. Available from: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2010~D_20100614_093721-35395 ;
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete

Technical University of Lisbon
5.
Bizarro, Piedade Maria Dinis Bernardes.
Estenfiliose na couve coração-de-boi.
Degree: 2012, Technical University of Lisbon
URL: http://www.rcaap.pt/detail.jsp?id=oai:www.repository.utl.pt:10400.5/5307
► Mestrado em Engenharia Agronómica - Hortofruticultura e Viticultura - Instituto Superior de Agronomia
This study aims to contribute to the diagnosis of brown spot of…
(more)
▼ Mestrado em Engenharia Agronómica - Hortofruticultura e Viticultura - Instituto Superior de Agronomia
This study aims to contribute to the diagnosis of brown spot of spitzkool cabbages, clarifying
symptoms associated with the disease and its evolution in the final stage of field. We
identified the causative agent of the disease as Stemphylium sp. by classical methods of
mycology and sequencing fragments amplified by PCR of DNA purified from cabbage leaves
with injuries, which has shown very significant homologies with the fungal genus
Stemphylium.
We tested the biological efficacy of six fungicides for Stemphylium sp. in in vitro studies. The
mycelial growth was inhibited by more evidence fungicide pyraclostrobin + boscalid,
pyraclostrobin and difenoconazole + dimethomorph. Based on these results, were selected
pyraclostrobin and boscalid + difenoconazole to assess inhibition of spore germination. The
fungicide used the first showed efficacy.
We evaluated the disease from its onset in a field production, in field subjected to
conventional treatments scheme and control field treated with water and refrigerated
conditions. The disease was detectable one week before the harvest in the field treated with
water, but over time disease developed in a stronger manner in the field treated with
fungicides. During storage, room temperature conducted to the development of more spots in
the cabbages that refrigeration conditions.
Advisors/Committee Members: Rego, Maria Cecília Farinha, Mota, Mariana Gomes.
Subjects/Keywords: spitzkool cabbage; Brassica oleracea L. var. capitata; brown spot; Stemphylium sp.
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
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APA (6th Edition):
Bizarro, P. M. D. B. (2012). Estenfiliose na couve coração-de-boi. (Thesis). Technical University of Lisbon. Retrieved from http://www.rcaap.pt/detail.jsp?id=oai:www.repository.utl.pt:10400.5/5307
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Bizarro, Piedade Maria Dinis Bernardes. “Estenfiliose na couve coração-de-boi.” 2012. Thesis, Technical University of Lisbon. Accessed January 22, 2021.
http://www.rcaap.pt/detail.jsp?id=oai:www.repository.utl.pt:10400.5/5307.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Bizarro, Piedade Maria Dinis Bernardes. “Estenfiliose na couve coração-de-boi.” 2012. Web. 22 Jan 2021.
Vancouver:
Bizarro PMDB. Estenfiliose na couve coração-de-boi. [Internet] [Thesis]. Technical University of Lisbon; 2012. [cited 2021 Jan 22].
Available from: http://www.rcaap.pt/detail.jsp?id=oai:www.repository.utl.pt:10400.5/5307.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Bizarro PMDB. Estenfiliose na couve coração-de-boi. [Thesis]. Technical University of Lisbon; 2012. Available from: http://www.rcaap.pt/detail.jsp?id=oai:www.repository.utl.pt:10400.5/5307
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
6.
MELO, Janaína Gonçalves da Silva.
Caracterização química e avaliação de atividade biológica dos metabólitos de actinobactéria endofítica isolada de Momordica charantia L
.
Degree: 2013, Universidade Federal de Pernambuco
URL: http://repositorio.ufpe.br/handle/123456789/13386
► Endofíticos são micro-organismos que colonizam o interior das plantas sem aparentemente causar danos ao seu hospedeiro, sendo encontrados em órgãos e tecidos vegetais como folhas,…
(more)
▼ Endofíticos são micro-organismos que colonizam o interior das plantas sem aparentemente causar danos ao seu hospedeiro, sendo encontrados em órgãos e tecidos vegetais como folhas, ramos e raízes. Em geral produzem metabólitos secundários de interesse farmacológicos, como também aplicáveis no controle biológico de pragas e doenças. O presente trabalho teve como objetivo investigar a atividade biológica e a caracterização química dos metabólitos secundários do Streptomyces
sp. UFPEDA 3345 endofítico isolado de folhas de Momordica charantia
L.. A fermentação em cultivo submerso desta linhagem apresentou como melhores condições para produção de metabólitos bioativos o meio M1 com 72 horas de cultivo em pH alcalino. Os extratos acetoetílico do líquido metabólico (EBLM) e o metanólico da biomassa (EBB) foram submetidos aos ensaios de citotoxicidade frente a células tumorais, à avaliação do potencial hemolítico em eritrócitos de camundongos, toxicidade aguda, determinação da concentração mínima inibitória (CMI) e à prospecção química. O extrato metanólico da biomassa (EBB) foi cromatografado em coluna de sílica gel e a fração F4 foi analisada através de cromatografia líquida de alta eficiência (CLAE) resultando na obtenção de três subfrações C1, C2 e C3. Para a atividade citotóxica frente às linhagens HT-29 (carcinoma de cólon), HEp-2 (carcinoma de laringe), NCI-H292 (carcinoma de pulmão) e MCF-7 (carcinoma de mama) na dose única de 50 μg/mL, os extratos, frações e subfrações apresentaram percentual de inibição do crescimento celular entre 17 e 93%. Após a administração da dose de 2.000 mg/kg do extrato EBB em camundongos, não foram observados efeitos tóxicos, sinais visíveis de toxicidade sistêmica e morte dos animais. Quanto ao potencial hemolítico dos extratos, estes apresentaram concentração efetiva de CE50 > 500 μg/mL e não promoveram danos à membrana eritrocitária. As amostras apresentaram atividade antimicrobiana para bactérias Gram-positivas, Gram-negativas, bactéria álcool ácido resistente, fungo filamentoso, leveduras e fitopátogenos. O extrato EBLM apresentou valores de CMI menores para B. subtilis (15,62 μg/mL), M. luteus (7,8 μg/mL) e M. smegmatis (15,62 μg/mL) em comparação ao extrato EBB. A CMI para A. niger, C. albicans e C. krusei os valores variaram de 15,62 a 250 μg/mL. A fração F4 e a subfração C1 apresentaram valores de CMI iguais de 62,5 μg/mL para C. albicans, A. niger e M. smegmatis. Quanto aos valores de CMI dos extratos EBLM e EBB frente a fungos e bactérias fitopatogênicos variaram entre 15,62 a 500 μg/mL. A prospecção química demonstrou a presença de açúcares redutores, compostos fenólicos, mono/sesquiterpenos, triterpenos e esteróides. Os resultados evidenciam que a linhagem endofítica Streptomyces
sp. UFPEDA 3345 produz diferentes biomoléculas com diversas atividades biológicas.
Advisors/Committee Members: MELO, Sebastião José de (advisor), ARAÚJO, Janete Magali de (advisor).
Subjects/Keywords: Atividades biológicas;
Endofítico;
Momordica charantia L;
Streptomyces sp
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
MELO, J. G. d. S. (2013). Caracterização química e avaliação de atividade biológica dos metabólitos de actinobactéria endofítica isolada de Momordica charantia L
. (Thesis). Universidade Federal de Pernambuco. Retrieved from http://repositorio.ufpe.br/handle/123456789/13386
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
MELO, Janaína Gonçalves da Silva. “Caracterização química e avaliação de atividade biológica dos metabólitos de actinobactéria endofítica isolada de Momordica charantia L
.” 2013. Thesis, Universidade Federal de Pernambuco. Accessed January 22, 2021.
http://repositorio.ufpe.br/handle/123456789/13386.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
MELO, Janaína Gonçalves da Silva. “Caracterização química e avaliação de atividade biológica dos metabólitos de actinobactéria endofítica isolada de Momordica charantia L
.” 2013. Web. 22 Jan 2021.
Vancouver:
MELO JGdS. Caracterização química e avaliação de atividade biológica dos metabólitos de actinobactéria endofítica isolada de Momordica charantia L
. [Internet] [Thesis]. Universidade Federal de Pernambuco; 2013. [cited 2021 Jan 22].
Available from: http://repositorio.ufpe.br/handle/123456789/13386.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
MELO JGdS. Caracterização química e avaliação de atividade biológica dos metabólitos de actinobactéria endofítica isolada de Momordica charantia L
. [Thesis]. Universidade Federal de Pernambuco; 2013. Available from: http://repositorio.ufpe.br/handle/123456789/13386
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

West Virginia University
7.
Jahan, Md. Asraful.
GENETIC REGULATION OF THE ELICITATION OF GLYCEOLLIN BIOSYNTHESIS IN SOYBEAN.
Degree: PhD, Not Listed, 2019, West Virginia University
URL: https://doi.org/10.33915/etd.3782
;
https://researchrepository.wvu.edu/etd/3782
► Glyceollin phytoalexins are the pathogen-elicited defense metabolites that belong to the isoflavonoid family of molecules of soybean (Glycine max L. Merr). Phytophthora root and…
(more)
▼ Glyceollin phytoalexins are the pathogen-elicited defense metabolites that belong to the isoflavonoid family of molecules of soybean (
Glycine max L. Merr). Phytophthora root and stem rot of soybean caused by
Phytophthora sojae is a destructive disease throughout the soybean-growing regions worldwide causing devastating economic damages (globally 1-2 billion and over 250 million in the USA) every year. Engineering soybean plants that produce higher levels of glyceollins could confer resistance against this pathogen. Glyceollins also show anticancer and neuroprotective activities in mammals, therefore they are important for agriculture and medical research. Firstly, we were interested in understanding how biotic and chemical elicitors regulate glyceollin biosynthesis differently. We found that combining the biotic elicitor WGE (wall glucan elicitor) extracted for
P. sojae and the chemical elicitor silver nitrate had an additive effect on the elicitation of glyceollins I. They elicited glyceollins by separate biosynthetic mechanisms. We treated soybean seedlings with a panel of abiotic stress conditions and found that acidic medium elicited the highest amount of glyceollins in root tissues of 1700µg gt
-1 (gram tissue, Fresh Weight). Then we focused on the identification of transcription factors (TFs) that regulate the biosynthesis of glyceollins in response to abiotic and biotic stress. Based on a comparative transcriptomics approach using RNA-seq, we chose to functionally characterize the
NAC (NAM/ATAF1/CUC2) family TF
GmNAC42-1, a homolog of the camalexin regulator
ANAC042 from Arabidopsis and an R2R3-MYB (myeloblastosis)-type TF
GmMYB29A2, the homolog of the stilbene regulator
VvMYB14 from grapevine. Overexpressing and RNAi silencing of
GmNAC42-1 and
GmMYB29A2 in WGE-elicited hairy roots resulted in significantly increased and decreased accumulation of glyceollin metabolites and biosynthesis gene transcripts such as
glycinol 4-dimethylallyl transferase (
G4DT) and
isoflavone synthase2 (
IFS2). The GmNAC42–1 and GmMYB29A2 proteins directly bound the promoters of glyceollin biosynthesis genes
IFS2 and
G4DT in the yeast one-hybrid (Y1H) system and localized to the nucleus when expressed with an N-terminal green fluorescent protein (GFP) tag. EMSA (Electrophoretic Mobility Shift Assay) confirmed that MYB29A2 protein binds glyceollin gene promoters. Overall, our findings indicate that
GmNAC42–1 and
GmMYB29A2 are essential components of a glyceollin gene regulatory network (GRN) and could be used for the large-scale, economic bioproduction of glyceollins for therapeutic use and to enhance resistance against
P. sojae.
Advisors/Committee Members: Nikola Kovinich, Daniel G. Panaccione, Daniel G. Panaccione.
Subjects/Keywords: Glyceollins; Isoflavonoids; NAC; MYB; Phytoalexin; Transcription factor; Bioproduction; P. sojae; Resistance; Soybean [Glycine max (L.) Merr.]; Agricultural Science; Genetics; Molecular Genetics; Plant Breeding and Genetics; Plant Pathology
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Jahan, M. A. (2019). GENETIC REGULATION OF THE ELICITATION OF GLYCEOLLIN BIOSYNTHESIS IN SOYBEAN. (Doctoral Dissertation). West Virginia University. Retrieved from https://doi.org/10.33915/etd.3782 ; https://researchrepository.wvu.edu/etd/3782
Chicago Manual of Style (16th Edition):
Jahan, Md Asraful. “GENETIC REGULATION OF THE ELICITATION OF GLYCEOLLIN BIOSYNTHESIS IN SOYBEAN.” 2019. Doctoral Dissertation, West Virginia University. Accessed January 22, 2021.
https://doi.org/10.33915/etd.3782 ; https://researchrepository.wvu.edu/etd/3782.
MLA Handbook (7th Edition):
Jahan, Md Asraful. “GENETIC REGULATION OF THE ELICITATION OF GLYCEOLLIN BIOSYNTHESIS IN SOYBEAN.” 2019. Web. 22 Jan 2021.
Vancouver:
Jahan MA. GENETIC REGULATION OF THE ELICITATION OF GLYCEOLLIN BIOSYNTHESIS IN SOYBEAN. [Internet] [Doctoral dissertation]. West Virginia University; 2019. [cited 2021 Jan 22].
Available from: https://doi.org/10.33915/etd.3782 ; https://researchrepository.wvu.edu/etd/3782.
Council of Science Editors:
Jahan MA. GENETIC REGULATION OF THE ELICITATION OF GLYCEOLLIN BIOSYNTHESIS IN SOYBEAN. [Doctoral Dissertation]. West Virginia University; 2019. Available from: https://doi.org/10.33915/etd.3782 ; https://researchrepository.wvu.edu/etd/3782
8.
Κουρτέσης, Αντώνιος.
Η επίδραση της N-Acetyl L-Cysteine στη προστασία του πνεύμονα χοίρου στο σύνδρομο ισχαιμίας - επαναιμάτωσης.
Degree: 2009, National and Kapodistrian University of Athens; Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών (ΕΚΠΑ)
URL: http://hdl.handle.net/10442/hedi/24357
► Background: The purpose of the present study was to investigate the effect of N-acetyl-L-cysteine on lung ischaemia reperfusion injury. Methods: Nineteen pigs were used. Group…
(more)
▼ Background: The purpose of the present study was to investigate the effect of N-acetyl-L-cysteine on lung ischaemia reperfusion injury. Methods: Nineteen pigs were used. Group I (n = 5) underwent sham operation, group II (n = 7) 90-min left-lung ischaemia followed by 180-min reperfusion. In group III (n = 7) N-acetyl-L-cysteine was given (160 mg/kg) during ischaemia into the pulmonary artery. Lung-functional and haemodynamic parameters were measured; serum and lung tissue samples were obtained and analysed for interleukin-10 and tumour necrosis factor-a. At the end of the reperfusion bronchoalveolar lavage was carried out from the ipsilateral lung and analysis for total protein, phospholipase-A2 and platelet-activating factor acetylhydrolase was carried out. Histological specimens were graded (0-3) for alveolar oedema, interstitial thickening and leucocyte infiltration. Statistical analysis was by means of one-way analysis of variance and Kruskal-Wallis test. Results: There were no differences in haemodynamic parameters, serum and tissue interleukin-10 and tissue necrosis factor-a. Pulmonary compliance was decreased in groups II and III (P = 0.002 and P = 0.001, respectively) during ischaemia and reperfusion. Pulmonary vascular resistance was increased in group II (P = 0.051) during reperfusion. In group III total protein and platelet activating factor acetylhydrolase were increased (P = 0.004 and P = 0.006, respectively) and phospholipase-A2 was reduced (P = 0.002), indicating an indirect surfactant-protective effect. Interstitial thickening was excessive in group II (P = 0.001); however, alveolar oedema was reduced (P = 0.002) when compared with group III. Conclusion: N-acetyl-L-cysteine when administered directly in the pulmonary artery showed no significant change in haemodynamic and functional lung parameters during ischaemia reperfusion; it does, however, have an indirect surfactant-protective effect.
Η μεταμόσχευση του πνεύμονα είναι πλέον µια ευρείας αποδοχής μέθοδος αντιμετώπισης ασθενών µε πνευµονική νόσο τελικού σταδίου Η πρώιµη δυσλειτουργία του μοσχεύματος αποτελεί µία από τις κυριότερες αιτίες νοσηρότητας και θνητότητας. H βλάβη εξ επαναιµατώσεως φαίνεται να είναι ο κυριότερος αιτιολογικός µηχανισµός. Η ακριβής παθογένεια του συνδρόµου ισχαιµίας - επαναιµάτωσης στις πνευµονικές µεταµοσχεύσεις δεν είναι πλήρως εξακριβωµένη. Τα ως τώρα εφαρµοζόµενα πειραµατικά πρωτόκολλα φαίνεται ότι δεν µπορούν να αναπαράγουν την πλήρη κλινική εικόνα του συνδρόµου ισχαιµίας επαναιµάτωσης, όπως είναι η υποξία, η σοβαρή βλάβη του ενδοθηλίου των πνευµονικών αγγείων, η αύξηση της τριχοειδικής διαπερατότητας και το εκσεσηµασµένο κυψελιδικό οίδηµα. Η επιτυχημένη µεταµόσχευση πνεύμονα προϋποθέτει βέλτιστη προστασία και διατήρηση του µοσχεύµατος. Εργαστηριακές µελέτες έχουν δείξει ότι τα ενδοθηλιακά κύτταρα και τα πνευµονοκύτταρα τύπου ΙΙ επηρεάζονται σοβαρά όχι µόνο κατά τη διαδικασία διατήρησης, αλλά και κατά τη φάση της επαναιµάτωσης 104,105. Μελέτες σε πειραματόζωα έχουν αποδείξει ότι κατά τις µεταµοσχεύσεις…
Subjects/Keywords: Ισχαιμία; Επαναιμάτωση; Πνεύμονας χοίρου; N-Acetyl-L-Cysteine; NAC; Ischemia; Reperfusion; Lung; Injury
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Κουρτέσης, . . (2009). Η επίδραση της N-Acetyl L-Cysteine στη προστασία του πνεύμονα χοίρου στο σύνδρομο ισχαιμίας - επαναιμάτωσης. (Thesis). National and Kapodistrian University of Athens; Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών (ΕΚΠΑ). Retrieved from http://hdl.handle.net/10442/hedi/24357
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Κουρτέσης, Αντώνιος. “Η επίδραση της N-Acetyl L-Cysteine στη προστασία του πνεύμονα χοίρου στο σύνδρομο ισχαιμίας - επαναιμάτωσης.” 2009. Thesis, National and Kapodistrian University of Athens; Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών (ΕΚΠΑ). Accessed January 22, 2021.
http://hdl.handle.net/10442/hedi/24357.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Κουρτέσης, Αντώνιος. “Η επίδραση της N-Acetyl L-Cysteine στη προστασία του πνεύμονα χοίρου στο σύνδρομο ισχαιμίας - επαναιμάτωσης.” 2009. Web. 22 Jan 2021.
Vancouver:
Κουρτέσης . Η επίδραση της N-Acetyl L-Cysteine στη προστασία του πνεύμονα χοίρου στο σύνδρομο ισχαιμίας - επαναιμάτωσης. [Internet] [Thesis]. National and Kapodistrian University of Athens; Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών (ΕΚΠΑ); 2009. [cited 2021 Jan 22].
Available from: http://hdl.handle.net/10442/hedi/24357.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Κουρτέσης . Η επίδραση της N-Acetyl L-Cysteine στη προστασία του πνεύμονα χοίρου στο σύνδρομο ισχαιμίας - επαναιμάτωσης. [Thesis]. National and Kapodistrian University of Athens; Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών (ΕΚΠΑ); 2009. Available from: http://hdl.handle.net/10442/hedi/24357
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
9.
Uzunhan, Yurdagül.
Effet des cellules souches mésenchymateuses dans les altérations épithéliales alvéolaires induites par l'hypoxie : Non communiqué.
Degree: Docteur es, Biologie, 2015, Sorbonne Paris Cité
URL: http://www.theses.fr/2015USPCD103
► La fibrose pulmonaire idiopathique (FPI) et le syndrome de détresse respiratoire aiguë (SDRA) de l’adulte constituent des affections sévères et létales du poumon profond associées…
(more)
▼ La fibrose pulmonaire idiopathique (FPI) et le syndrome de détresse respiratoire aiguë (SDRA) de l’adulte constituent des affections sévères et létales du poumon profond associées à une hypoxie alvéolaire, pour lesquelles les ressources thérapeutiques sont limitées. La thérapie cellulaire utilisant des cellules souches mésenchymateuses humaines (CSMh) est actuellement envisagée dans ces pathologies, mais les mécanismes d’action des CSMh restent à élucider. Nous avons testé in vitro l’hypothèse selon laquelle les CSMh pourraient exercer un effet cytoprotecteur paracrine sur les cellules épithéliales alvéolaires (CEA) soumises à l’hypoxie.Dans une première étude, nous avons montré que l’exposition aiguë de CSMh dérivées de moelle osseuse à un environnement inflammatoire (traitement par cytomix constitué de TNFα, d’Interféron Ƴ et d’Interleukine 1β) et hypoxique (3% O₂) mimant le microenvironnement alvéolaire du SDRA ne modifiait pas le phénotype ou la viabilité des cellules mais induisait des modifications de leur secretome, notamment de facteurs connus pour réguler le transport trans-épithélial alvéolaire de sodium (Na) et la réabsorption de l’oedème alvéolaire : IL1-ra, PGE2 et KGF. Le milieu de culture des CSMh (MC-CSMh), qu’il soit obtenu en normoxie ou en hypoxie-cytomix, prévenait l’augmentation de la perméabilité épithéliale des CEA primaires de rat cultivées sur support semi-perméable et exposées à l’hypoxie et au cytomix. Le MC-CSMh provenant de CSMh cultivées en normoxie prévenait l’inhibition du transport transépithélial alvéolaire de Na en restaurant l’expression à la surface de la sous-unité α du canal sodique épithélial ENaC, tandis que le MC-CSMh obtenu sous hypoxie-cytomix n’avait pas d’effet protecteur. La sécrétion de Keratinocyte Growth Factor (KGF) par les CSMh était indispensable à leur effet protecteur.Dans une seconde étude, nous avons montré qu’une exposition prolongée à l’hypoxie telle que rencontrée au cours de la FPI induisait des modifications phénotypiques des CEA de rat évocatrices de transition épithélio-mésenchymateuse (TEM) avec perte progressive d’expression des marqueurs épithéliaux (TTF1, AQP5, ZO-1 et E-Cadhérine) couplée à l’apparition tardive de marqueurs mésenchymateux (α -SMA et Vimentine). Ces modifications phénotypiques s’accompagnaient de l’expression à la phase initiale de l’hypoxie de facteurs de transcription impliqués dans la TEM (SNAI1, TWIST1 et ZEB1) ou induits par l’hypoxie (HIF-1α et HIF-2α et de protéines induisant la TEM (TGFβ1 et CTGF). La co-culture des CEA avec des CSMh en fond de puits prévenait les modifications phénotypiques induites par l’hypoxie ainsi que l’expression des facteurs pro-TEM TWIST1, ZEB1, TGFβ1 et CTGF. Là encore, le KGF était au moins en partie responsable des effets protecteurs des CSMh.Ces deux études indiquent que les CSMh sont susceptibles d’exercer des effets cytoprotecteurs paracrines vis-à-vis des CEA soumises à l’hypoxie aiguë ou prolongée, en limitant d’une part les effets de délétères de l’hypoxie sur les propriétés de transport…
Advisors/Committee Members: Planès, Carole (thesis director).
Subjects/Keywords: Pneumocytes; E-NaC; Pneumocytes
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Uzunhan, Y. (2015). Effet des cellules souches mésenchymateuses dans les altérations épithéliales alvéolaires induites par l'hypoxie : Non communiqué. (Doctoral Dissertation). Sorbonne Paris Cité. Retrieved from http://www.theses.fr/2015USPCD103
Chicago Manual of Style (16th Edition):
Uzunhan, Yurdagül. “Effet des cellules souches mésenchymateuses dans les altérations épithéliales alvéolaires induites par l'hypoxie : Non communiqué.” 2015. Doctoral Dissertation, Sorbonne Paris Cité. Accessed January 22, 2021.
http://www.theses.fr/2015USPCD103.
MLA Handbook (7th Edition):
Uzunhan, Yurdagül. “Effet des cellules souches mésenchymateuses dans les altérations épithéliales alvéolaires induites par l'hypoxie : Non communiqué.” 2015. Web. 22 Jan 2021.
Vancouver:
Uzunhan Y. Effet des cellules souches mésenchymateuses dans les altérations épithéliales alvéolaires induites par l'hypoxie : Non communiqué. [Internet] [Doctoral dissertation]. Sorbonne Paris Cité; 2015. [cited 2021 Jan 22].
Available from: http://www.theses.fr/2015USPCD103.
Council of Science Editors:
Uzunhan Y. Effet des cellules souches mésenchymateuses dans les altérations épithéliales alvéolaires induites par l'hypoxie : Non communiqué. [Doctoral Dissertation]. Sorbonne Paris Cité; 2015. Available from: http://www.theses.fr/2015USPCD103

University of Florida
10.
Howard, Leslie R.
Proteomic Analysis of the Effects of Ceftriaxone on Cocaine Induced Mitochondrial Dysfunction in the Nucleus Accumbens.
Degree: MS, Psychology, 2018, University of Florida
URL: https://ufdc.ufl.edu/UFE0052328
► Cocaine self-administration followed by extinction leads to a decrease in basal extracellular glutamate in the NAc of the rat brain, likely due to downregulation of…
(more)
▼ Cocaine self-administration followed by extinction leads to a decrease in basal extracellular glutamate in the
NAc of the rat brain, likely due to downregulation of xCT. Relapse to cocaine seeking is accompanied by glutamate efflux in the
NAc. Ceftriaxone treatment following cocaine self-administration prevents the decrease in
NAc extracellular glutamate during extinction, likely due to an upregulation of xCT and GLT-1. Ceftriaxone attenuates reinstatement to cocaine seeking following self-administration and extinction, while preventing glutamate efflux in the
NAc. Ceftriaxone holds great promise as a pharmacotherapy for cocaine relapse, but little is known about protein interactions it targets. The goal of this study was to investigate ceftriaxone's mechanism of action via label-free proteomic analysis performed using nanoelectrospray ionization tandem MS with LTQ Orbitrap Elite mass spectrometer. 607 proteins displayed altered expression as a function of cocaine self-administration, 721 as a function of ceftriaxone and 728 as a function of cocaine-ceftriaxone treatment. Our results indicated proteins in the Mitochondrial Dysfunction canonical pathway were most significantly altered. Three proteins from this pathway were validated with western blots: Cox6c, Cox4I1, and ATP5a. Results revealed increased ATP5a expression in both cocaine groups relative to controls, in contrast with the proteomic analysis pattern where ATP5a had the highest abundance for controls and the lowest for the ceftriaxone group. Remaining western blots are in progress. Confirmation of these protein changes helps elucidate the role of mitochondria in cocaine addiction and understand underlying connections of ceftriaxone rescuing mitochondrial dysfunction as well as regulating glutamate homeostasis in the
NAc. ( en )
Advisors/Committee Members: KNACKSTEDT,LORI (committee chair), WANG,KA W (committee member).
Subjects/Keywords: ceftriaxone – cocaine – nac – proteomics
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APA ·
Chicago ·
MLA ·
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CSE |
Export
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APA (6th Edition):
Howard, L. R. (2018). Proteomic Analysis of the Effects of Ceftriaxone on Cocaine Induced Mitochondrial Dysfunction in the Nucleus Accumbens. (Masters Thesis). University of Florida. Retrieved from https://ufdc.ufl.edu/UFE0052328
Chicago Manual of Style (16th Edition):
Howard, Leslie R. “Proteomic Analysis of the Effects of Ceftriaxone on Cocaine Induced Mitochondrial Dysfunction in the Nucleus Accumbens.” 2018. Masters Thesis, University of Florida. Accessed January 22, 2021.
https://ufdc.ufl.edu/UFE0052328.
MLA Handbook (7th Edition):
Howard, Leslie R. “Proteomic Analysis of the Effects of Ceftriaxone on Cocaine Induced Mitochondrial Dysfunction in the Nucleus Accumbens.” 2018. Web. 22 Jan 2021.
Vancouver:
Howard LR. Proteomic Analysis of the Effects of Ceftriaxone on Cocaine Induced Mitochondrial Dysfunction in the Nucleus Accumbens. [Internet] [Masters thesis]. University of Florida; 2018. [cited 2021 Jan 22].
Available from: https://ufdc.ufl.edu/UFE0052328.
Council of Science Editors:
Howard LR. Proteomic Analysis of the Effects of Ceftriaxone on Cocaine Induced Mitochondrial Dysfunction in the Nucleus Accumbens. [Masters Thesis]. University of Florida; 2018. Available from: https://ufdc.ufl.edu/UFE0052328

Universidade Estadual de Campinas
11.
Martins, Thamires, 1987-.
Bovine mastitis : natural products as alternatives for treatment =Mastite bovina : produtos naturais como alternativas de tratamento: Mastite bovina : produtos naturais como alternativas de tratamento.
Degree: 2018, Universidade Estadual de Campinas
URL: http://repositorio.unicamp.br/jspui/handle/REPOSIP/350070
► Abstract: Bovine mastitis is a frequent pathology that causes high economic negative impact to the dairy industry. Antimicrobials are the main tool to treat this…
(more)
▼ Abstract: Bovine mastitis is a frequent pathology that causes high economic negative impact to the dairy industry. Antimicrobials are the main tool to treat this disease. The failure of existing antimicrobial treatments against multidrug resistant bacteria is increasingly common, making the search for new drugs effective against mastitis pathogens more urgent. Microorganisms and plants are promising sources of natural products with antibacterial action. Thus, the aim of this thesis was to search for natural products with antibacterial activity and to evaluate their potential use in the bovine mastitis treatment. In the period of 2010-2015, there were reported in the literature more than 50 antibacterial molecules obtained from marine substrates. Among them, anthracimycin, kocurin, macrolactins A1 and B1, gageotetrins A-C and gageomacrolactins 1-3 are examples of molecules with promising antibacterial activity and that could be investigated for the development of new drugs. Located at mid-Atlantic Ocean, the São Pedro and São Paulo Archipelago (ASPSP) is a place with unique characteristics that could offer a wide biodiversity, nevertheless it has been little studied. Microorganisms isolated from marine sponges collected around the ASPSP produced secondary metabolites with potential activity against methicillin-resistant Staphylococcus aureus (MRSA). One of them was the fungus Acremonium camptosporum, a ubiquitous microorganism isolated for the first time from the sponge Aplysina fulva. Mass spectra data obtained by UPLC-ESI-MS/MS revealed the presence of several acremonidins and acremoxanthones in the mycelial extract. These compounds are known to present high cytotoxicity, therefore, they were not considered as candidates to be used in veterinary formulations. However, it was verified that the chemical arsenal produced by A. camptosporum might play a fundamental role in the defense of the sponge, as well as of the fungus itself. On the other hand, essential oils are natural products known for their diverse biological properties. Thus, the essential oil (OE) from Baccharis dracunculifolia was subjected to a flash chromatography fractionation, obtaining fractions with high content of its major compounds, trans-nerolidol (91.47 - 96.14%) and spathulenol (78.63 - 84.89%). The OE and the trans-nerolidol and spathulenol fractions inhibited the growth of several S. aureus (MIC90 = 375 µg mL-1) and Streptococcus agalactiae (MIC90 = 187.5
Bovine mastitis is a frequent pathology that causes high economic negative impact to the dairy industry. Antimicrobials are the main tool to treat this disease. The failure of existing antimicrobial treatments against multidrug resistant bacteria is increasingly common, making the search for new drugs effective against mastitis pathogens more urgent. Microorganisms and plants are promising sources of natural products with antibacterial action. Thus, the aim of this thesis was to search for natural products with antibacterial activity and to evaluate their potential use in the bovine…
Advisors/Committee Members: UNIVERSIDADE ESTADUAL DE CAMPINAS (CRUESP), Reyes, Felix Guillermo Reyes, 1948- (advisor), Schinke, Claudia (coadvisor), Universidade Estadual de Campinas. Faculdade de Engenharia de Alimentos (institution), Programa de Pós-Graduação em Ciência de Alimentos (nameofprogram), Katiki, Luciana Morita (committee member), Roma Júnior, Luiz Carlos (committee member), Silva, Nathalia Cristina Cirone (committee member), Pareja, Martin Francisco (committee member).
Subjects/Keywords: Acremonium sp.; Agentes antibacterianos; Baccharis dracunculifolia L; Metabólitos; Essências e óleos essenciais; Aplysina fulva; Acremonium sp.; Antibacterial agents; Baccharis dracunculifolia; Metabolites; Essences and Essential oils; Aplysina fulva
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Martins, Thamires, 1. (2018). Bovine mastitis : natural products as alternatives for treatment =Mastite bovina : produtos naturais como alternativas de tratamento: Mastite bovina : produtos naturais como alternativas de tratamento. (Thesis). Universidade Estadual de Campinas. Retrieved from http://repositorio.unicamp.br/jspui/handle/REPOSIP/350070
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Martins, Thamires, 1987-. “Bovine mastitis : natural products as alternatives for treatment =Mastite bovina : produtos naturais como alternativas de tratamento: Mastite bovina : produtos naturais como alternativas de tratamento.” 2018. Thesis, Universidade Estadual de Campinas. Accessed January 22, 2021.
http://repositorio.unicamp.br/jspui/handle/REPOSIP/350070.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Martins, Thamires, 1987-. “Bovine mastitis : natural products as alternatives for treatment =Mastite bovina : produtos naturais como alternativas de tratamento: Mastite bovina : produtos naturais como alternativas de tratamento.” 2018. Web. 22 Jan 2021.
Vancouver:
Martins, Thamires 1. Bovine mastitis : natural products as alternatives for treatment =Mastite bovina : produtos naturais como alternativas de tratamento: Mastite bovina : produtos naturais como alternativas de tratamento. [Internet] [Thesis]. Universidade Estadual de Campinas; 2018. [cited 2021 Jan 22].
Available from: http://repositorio.unicamp.br/jspui/handle/REPOSIP/350070.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Martins, Thamires 1. Bovine mastitis : natural products as alternatives for treatment =Mastite bovina : produtos naturais como alternativas de tratamento: Mastite bovina : produtos naturais como alternativas de tratamento. [Thesis]. Universidade Estadual de Campinas; 2018. Available from: http://repositorio.unicamp.br/jspui/handle/REPOSIP/350070
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
12.
Litervaldo Pereira Machado.
Seleção para resistência à murcha-de-fusário em genótipos de algodoeiro.
Degree: 2008, Universidade Federal Rural de Pernambuco
URL: http://200.17.137.108/tde_busca/arquivo.php?codArquivo=282
► A murcha-de-fusário, causada pelo fungo Fusarium oxysporum f.sp. vasinfectum, é uma das principais doenças do algodoeiro em todo o mundo. Apesar da baixa incidencia da…
(more)
▼ A murcha-de-fusário, causada pelo fungo Fusarium oxysporum f.sp. vasinfectum, é uma das principais doenças do algodoeiro em todo o mundo. Apesar da baixa incidencia da doença no cerrado, principal região produtora do Brasil, a murcha-de-fusário tem preocupado os produtores de algodão na região em virtude de ser potencialmente destrutiva. A tática de manejo da doença mais desejável é o uso de cultivares resistentes. Neste trabalho desenvolveu-se um método para seleção de genótipos de algodoeiro, que consistiu no plantio de sementes de algodoeiro em bandejas de plástico para germinação, que foram dispostas em casa-de-vegetação climatizada. As células das bandejas foram preenchidas com vermiculita esterilizada, e em cada célula foi plantada uma semente. Aos 5 e 7 dias após o plantio, depositou-se, em cada célula, uma suspensão de esporos. Foram testados 64 genótipos de algodoeiro com intuito de avaliar a sua resistência à murcha-de-fusário. O uso desse método possibilitou a identificação de novas fontes com alta resistência a murcha-de-fusário, como os genótipos FM 993, Stoneville LA 887,CNPA GO 2002-3778 e HS 26.
The cotton wilt caused by Fusarium oxysporum f. sp. vasinfectum is one of the most important cotton diseases of the world. This disease is potentially destructive and had caused losses to cotton farms in the main cotton growing area in Brazil. The use of resistant cultivars is the main recommended practice to manage fusarium cotton wilt. In this study is described a simple, precise, and fast method to screen cotton germplasm for wilt resistance. By employing this method was identified new resistance sources of cotton genotypes to fusarium cotton wilt, as the genotypes FM 993, Stoneville LA 887, CNPA GO 2002-3778, and HS 26 among 64 accessions inoculated with a Brazilian pathogen population sample.
Advisors/Committee Members: Gaus Silvestre de Andrade Lima, Delson Laranjeira, Domingos Eduardo Guimarães Tavares de Andrade, Sami Jorge Michereff, Nelson Dias Suassuna.
Subjects/Keywords: Manejo; Epidemiologia; FITOPATOLOGIA; Cotton breeding; Genetic resistance; Melhoramento genético vegetal; Gossypium hirsutum L.; Fusarium oxysporum f. Sp. vasinfectum; Algodão
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Machado, L. P. (2008). Seleção para resistência à murcha-de-fusário em genótipos de algodoeiro. (Thesis). Universidade Federal Rural de Pernambuco. Retrieved from http://200.17.137.108/tde_busca/arquivo.php?codArquivo=282
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Machado, Litervaldo Pereira. “Seleção para resistência à murcha-de-fusário em genótipos de algodoeiro.” 2008. Thesis, Universidade Federal Rural de Pernambuco. Accessed January 22, 2021.
http://200.17.137.108/tde_busca/arquivo.php?codArquivo=282.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Machado, Litervaldo Pereira. “Seleção para resistência à murcha-de-fusário em genótipos de algodoeiro.” 2008. Web. 22 Jan 2021.
Vancouver:
Machado LP. Seleção para resistência à murcha-de-fusário em genótipos de algodoeiro. [Internet] [Thesis]. Universidade Federal Rural de Pernambuco; 2008. [cited 2021 Jan 22].
Available from: http://200.17.137.108/tde_busca/arquivo.php?codArquivo=282.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Machado LP. Seleção para resistência à murcha-de-fusário em genótipos de algodoeiro. [Thesis]. Universidade Federal Rural de Pernambuco; 2008. Available from: http://200.17.137.108/tde_busca/arquivo.php?codArquivo=282
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
13.
Litervaldo Pereira Machado.
Seleção para resistência à murcha-de-fusário em genótipos de algodoeiro.
Degree: 2008, Universidade Federal Rural de Pernambuco
URL: http://200.17.137.108/tde_busca/arquivo.php?codArquivo=282
► A murcha-de-fusário, causada pelo fungo Fusarium oxysporum f.sp. vasinfectum, é uma das principais doenças do algodoeiro em todo o mundo. Apesar da baixa incidencia da…
(more)
▼ A murcha-de-fusário, causada pelo fungo Fusarium oxysporum f.sp. vasinfectum, é uma das principais doenças do algodoeiro em todo o mundo. Apesar da baixa incidencia da doença no cerrado, principal região produtora do Brasil, a murcha-de-fusário tem preocupado os produtores de algodão na região em virtude de ser potencialmente destrutiva. A tática de manejo da doença mais desejável é o uso de cultivares resistentes. Neste trabalho desenvolveu-se um método para seleção de genótipos de algodoeiro, que consistiu no plantio de sementes de algodoeiro em bandejas de plástico para germinação, que foram dispostas em casa-de-vegetação climatizada. As células das bandejas foram preenchidas com vermiculita esterilizada, e em cada célula foi plantada uma semente. Aos 5 e 7 dias após o plantio, depositou-se, em cada célula, uma suspensão de esporos. Foram testados 64 genótipos de algodoeiro com intuito de avaliar a sua resistência à murcha-de-fusário. O uso desse método possibilitou a identificação de novas fontes com alta resistência a murcha-de-fusário, como os genótipos FM 993, Stoneville LA 887,CNPA GO 2002-3778 e HS 26.
The cotton wilt caused by Fusarium oxysporum f. sp. vasinfectum is one of the most important cotton diseases of the world. This disease is potentially destructive and had caused losses to cotton farms in the main cotton growing area in Brazil. The use of resistant cultivars is the main recommended practice to manage fusarium cotton wilt. In this study is described a simple, precise, and fast method to screen cotton germplasm for wilt resistance. By employing this method was identified new resistance sources of cotton genotypes to fusarium cotton wilt, as the genotypes FM 993, Stoneville LA 887, CNPA GO 2002-3778, and HS 26 among 64 accessions inoculated with a Brazilian pathogen population sample.
Advisors/Committee Members: Sami Jorge Michereff, Domingos Eduardo Guimarães Tavares de Andrade, Gaus Silvestre de Andrade Lima, Delson Laranjeira, Nelson Dias Suassuna.
Subjects/Keywords: Genetic resistance; Manejo; Algodão; Melhoramento genético vegetal; Gossypium hirsutum L.; FITOPATOLOGIA; Epidemiologia; Cotton breeding; Fusarium oxysporum f. Sp. vasinfectum
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Machado, L. P. (2008). Seleção para resistência à murcha-de-fusário em genótipos de algodoeiro. (Thesis). Universidade Federal Rural de Pernambuco. Retrieved from http://200.17.137.108/tde_busca/arquivo.php?codArquivo=282
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Machado, Litervaldo Pereira. “Seleção para resistência à murcha-de-fusário em genótipos de algodoeiro.” 2008. Thesis, Universidade Federal Rural de Pernambuco. Accessed January 22, 2021.
http://200.17.137.108/tde_busca/arquivo.php?codArquivo=282.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Machado, Litervaldo Pereira. “Seleção para resistência à murcha-de-fusário em genótipos de algodoeiro.” 2008. Web. 22 Jan 2021.
Vancouver:
Machado LP. Seleção para resistência à murcha-de-fusário em genótipos de algodoeiro. [Internet] [Thesis]. Universidade Federal Rural de Pernambuco; 2008. [cited 2021 Jan 22].
Available from: http://200.17.137.108/tde_busca/arquivo.php?codArquivo=282.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Machado LP. Seleção para resistência à murcha-de-fusário em genótipos de algodoeiro. [Thesis]. Universidade Federal Rural de Pernambuco; 2008. Available from: http://200.17.137.108/tde_busca/arquivo.php?codArquivo=282
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Saskatchewan
14.
Nabetani, Keiko.
Stripe rust management in spring and winter wheat by varietal resistance and fungicide application.
Degree: 2020, University of Saskatchewan
URL: http://hdl.handle.net/10388/12808
► Stripe rust of wheat, caused by Puccinia striiformis f. sp. tritici Eriks., is prevalent throughout western Canada in some years. As a result, there is…
(more)
▼ Stripe rust of wheat, caused by Puccinia striiformis f.
sp. tritici Eriks., is prevalent throughout western Canada in some years. As a result, there is a need to study stripe rust control for winter wheat grown in western Canada. The objective of the first thesis project was to evaluate the effects of fall fungicide application (metconazole and pyraclostrobin) on stripe rust and leaf spot severity, as well as yield and quality of winter wheat. The effects of fungicide application in the fall, spring, or both fall and spring (dual) on four winter wheat cultivars varying in disease resistance: ‘AC Bellatrix,’ ‘Moats,’ ‘Radiant,’ and ‘CDC Osprey’ were evaluated at four sites: Saskatoon and Indian Head in SK and Lethbridge and Lacombe in AB. Stripe rust severity on susceptible cultivars, ‘AC Bellatrix’ and ‘CDC Osprey,’ and leaf spot severity on these cultivars and ‘Radiant,’ were reduced by a single spring or dual fungicide applications (fall and spring) but not by fall application when over-all disease severity was high. Single spring and dual fungicide applications on stripe rust susceptible cultivars maintained yield potential compared to the unsprayed treatment, which was reduced by nearly 30%; grain quality was also maintained by the same treatments. The stripe rust resistant cultivar ‘Moats’ was not affected by fungicide application at any timing. Fall fungicide application had no effect on disease severity, yield or grain quality during the study. The dual fungicide application did not offer additional benefits.
Race-specific stripe rust resistance genes (Yr genes) are widely deployed in wheat cultivars to control stripe rust. However, race-specific resistance break-down by the pathogen occurs frequently. The residual effects, the expression of partial, non race-specific resistance to virulent pathogen races by defeated race-specific disease resistance genes, is a potential source of durable stripe rust resistance. In the second project, the residual effects of race-specific Yr genes in wheat were evaluated. The parental near isogenic lines (NILs) with defeated single Yr genes (Yr10, Yr26, and Yr32) in the ‘Avocet’ background, F5 NILs with two Yr genes in the combinations of Yr26/Yr10, Yr32/Yr10 and Yr32/Yr26 and the susceptible cultivar ‘Avocet-S’ were inoculated with each Pst isolate or isolate mixtures (W020, W049, T034/W052) virulent to all three Yr genes in growth chambers. Infection type (IT), infection area (IA) and latent period (LP) were assessed and recorded. An increased number of Yr genes was correlated with reduced IT and IA and longer LP. The same NILs were evaluated in stripe rust field nurseries at Saskatoon, SK and Lethbridge, AB in 2018. There was an interaction between genotypes and isolates, and correlations between increasing numbers of Yr genes and all parameters. When inoculated with T034/W052, Yr32/Yr10 and Yr32/Yr26 wheat genotypes had lower IT and IA and longer LP than ‘Avocet-S’. With two other isolates, Yr32/Yr10 and Yr32/Yr26 wheat genotypes tended to have lower IA and longer LP than…
Advisors/Committee Members: Kutcher, H. Randy, Booker, Helen, Hucl, Pierre J., Shirtliffe, Steve, Duncan, Roberet W..
Subjects/Keywords: Stripe rust; Puccinia striiformis f. sp. tritici; wheat; Triticum aestivum L.; winter wheat; fungicide application timing; residual effect; defeated gene
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Nabetani, K. (2020). Stripe rust management in spring and winter wheat by varietal resistance and fungicide application. (Thesis). University of Saskatchewan. Retrieved from http://hdl.handle.net/10388/12808
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Nabetani, Keiko. “Stripe rust management in spring and winter wheat by varietal resistance and fungicide application.” 2020. Thesis, University of Saskatchewan. Accessed January 22, 2021.
http://hdl.handle.net/10388/12808.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Nabetani, Keiko. “Stripe rust management in spring and winter wheat by varietal resistance and fungicide application.” 2020. Web. 22 Jan 2021.
Vancouver:
Nabetani K. Stripe rust management in spring and winter wheat by varietal resistance and fungicide application. [Internet] [Thesis]. University of Saskatchewan; 2020. [cited 2021 Jan 22].
Available from: http://hdl.handle.net/10388/12808.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Nabetani K. Stripe rust management in spring and winter wheat by varietal resistance and fungicide application. [Thesis]. University of Saskatchewan; 2020. Available from: http://hdl.handle.net/10388/12808
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universitat Politècnica de València
15.
Ribeiro Teresani, Gabriela.
Candidatus Liberibacter solanacearum: detection, characterization, new hosts and epidemiology in Spain
.
Degree: 2015, Universitat Politècnica de València
URL: http://hdl.handle.net/10251/48459
► ‘Candidatus Liberibacter solanacearum’ is a α-Proteo bacteria, Gram-negative, restricted to plant phloem and to the haemolymph of psyllids that act as vectors. This emerging bacterium…
(more)
▼ ‘Candidatus Liberibacter solanacearum’ is a α-Proteo
bacteria, Gram-negative, restricted to plant phloem and to the
haemolymph of psyllids that act as vectors. This emerging
bacterium has been associated with different diseases in different
hosts and associated with carrot (Daucus carota) in Spain.
Vegetative disorders of unknown etiology have also been observed
in celery (Apium graveolens) since 2008.
A real-time PCR protocol specific to ‘Ca.
L. solanacearum’
detection, using TaqMan probe and direct sample preparation
methods have been developed. This technology has been validated
in an intra-laboratory study (sensitivity 1, specificity 1 and accuracy
100%) and is available commercially as a complete kit. It has been
demonstrated that ‘Ca.
L. solanacearum’ is associated with the
observed syndrome in celery and a new bacterium haplotype (E)
has been identified. With these results it is concluded that celery is a
new host of ‘Ca.
L. solanacearum’ (Teresani et al., 2014a).
Using the newly developed real-time PCR protocol ‘Ca.
L.
solanacearum’ has been detected in 42,6% of the carrot seeds lots
tested and in individual seeds. The number of cells/seeds has been
estimated in 4.8±3.3 to 210±6.7, which only 5% were viable. After
150 days post-germination, 12% of seedlings showed symptoms
and tested positive for ‘Ca.
L. solanacearum’. Liberibacter-like cells
were observed in the phloem sieve elements of the seed coat and in
the phloem of carrot leaf midrib from seedlings. These results demonstrated that ‘Ca.
L. solanacearum’ is transmitted by carrot
seeds (Bertolini et al., 2014b).
The collected arthropods were classified into families, and
the superfamily Psylloidea was identified to the species level
resulting Bactericera trigonica, B. tremblayi and B. nigricornis the
main identified species. The population dynamics of different
psyllids species visiting carrot, celery and potato has been
determined, concluding that the highest populations are captured
during summer. The bacterium has been detected in the different
Bactericera species previous cited additionally to Bactericera
sp.
The psyllid species carrying the bacteria can be considered as
possible vectors of the bacterium (Teresani et al. 2014b).
Electrical Penetration Graphs showed that B. trigonica was
able to feed in the phloem of carrot, celery and potato but not in the
phloem of tomato plants. Experimental transmission showed that B.
trigonica transmitted ‘Ca.
L. solanacearum’ from carrot to carrot,
celery, potato and tomato. More efficient transmission occurred
with ten individuals, and the transmission rates were 100% in
celery, 80% in carrot and 10% in potato and tomato. The
experimental transmission to potatoes threatens this crop (Teresani
et al., 2014c).
These combined results have built a scientific foundation of
the biological and epidemiological aspects of ‘Ca.
L. solanacearum’
contributing to new scientific information that is key in cultivation
of celery and carrot to establish bacteria control strategies.…
Advisors/Committee Members: Bertolini, Edson (advisor), Cambra Alvarez, Mariano J (advisor), Lopez Gonzalez, Maria Milagros (advisor).
Subjects/Keywords: Bacterium;
'Ca. L. solanacearum';
Detection;
Quantification;
Cell viability;
Real-time PCR;
Seedborne bacterium;
Electron microscopy;
Bactericera sp;
Celery;
Carrot
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Ribeiro Teresani, G. (2015). Candidatus Liberibacter solanacearum: detection, characterization, new hosts and epidemiology in Spain
. (Doctoral Dissertation). Universitat Politècnica de València. Retrieved from http://hdl.handle.net/10251/48459
Chicago Manual of Style (16th Edition):
Ribeiro Teresani, Gabriela. “Candidatus Liberibacter solanacearum: detection, characterization, new hosts and epidemiology in Spain
.” 2015. Doctoral Dissertation, Universitat Politècnica de València. Accessed January 22, 2021.
http://hdl.handle.net/10251/48459.
MLA Handbook (7th Edition):
Ribeiro Teresani, Gabriela. “Candidatus Liberibacter solanacearum: detection, characterization, new hosts and epidemiology in Spain
.” 2015. Web. 22 Jan 2021.
Vancouver:
Ribeiro Teresani G. Candidatus Liberibacter solanacearum: detection, characterization, new hosts and epidemiology in Spain
. [Internet] [Doctoral dissertation]. Universitat Politècnica de València; 2015. [cited 2021 Jan 22].
Available from: http://hdl.handle.net/10251/48459.
Council of Science Editors:
Ribeiro Teresani G. Candidatus Liberibacter solanacearum: detection, characterization, new hosts and epidemiology in Spain
. [Doctoral Dissertation]. Universitat Politècnica de València; 2015. Available from: http://hdl.handle.net/10251/48459
16.
Silva, Wellington Costa da.
Influência de sucessões de cultivos na severidade da murcha-de-fusário do caupi.
Degree: 2011, Universidade Federal de Alagoas
URL: http://www.repositorio.ufal.br/handle/riufal/260
► The cowpea is very important for the poor populations of the North and Northeast of the Brazil. Several factors corroborate to production low of the…
(more)
▼ The cowpea is very important for the poor populations of the North and Northeast of the Brazil. Several factors corroborate to production low of the culture, among them we can quote the disease, focusing on cowpea Fusarium wilt , caused by the fungus Fusarium oxysporum f.sp. tracheiphilum. This study aimed to evaluate the influence of incorporation of crop succession on the severity of cowpea Fusarium wilt. In all experiments we used soil without previous history of cultivation with this culture. There were no observed F. oxysporum populations indigenous in the soil. The experiments were conducted in microplots of concrete pipes containing soil artificially infested with the pathogen structures, the density of 5x103 cfu g-1 of soil. The experiment consisted of three cultivation cycles being: (i) cowpea, (ii) succession cultural and (iii) cowpea. The culture succession were: corn - MI, sorghum - SO, cotton - AL, castor - MN and sunflower - GI; legumes: Crotalaria juncea - CJ, Crotalaria spectabilis - CS, bean-pig - FP, pigeon pea Dwarf - GA, lab-lab - LA and black velvet - velvet MP and dwarf - MA. There were still some treatments: plots with cowpea without inoculum of F. o. f. sp. tracheiphilum - TEST, plots of cowpea inoculated with F. o. f. sp. tracheiphilum (cowpea) - CA, and plots infested with the pathogen in fallow system - PO. The incorporation of succession before of the cowpea planting provided a range in the disease severity of 56.67% to 26.33%. Among the legumes studied the FP and MP were the most suitable for reducing the severity of the disease and offer better grain yield. For succession crops to the OS and GI showed a greater reduction in severity of Fusarium wilt of cowpea.
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
O feijão-caupi é muito importante para as populações carentes do Norte e Nordestes brasileiro. Diversos fatores corroboram para as baixas produções da cultura, dentre eles podemos destacar as doenças, com foco à murcha-de-fusário do feijão-caupi, causada pelo fungo Fusarium oxysporum f.sp. tracheiphilum. O presente trabalho teve como objetivo avaliar a influência da incorporação de sucessões de cultivo na severidade da murcha-de-fusário do feijão-caupi. Em todos os experimentos utilizouse solo sem histórico anterior de cultivo com a cultura. Não foram detectadas populações autóctones de F. oxysporum no solo. Os experimentos foram conduzidos em microparcelas constituídas de manilhas de concreto contendo solo infestado artificialmente com estruturas do patógeno, na densidade de 5x103 ufc g-1 de solo. O experimento foi constituído de três ciclos de cultivos: (i) feijão-caupi, (ii) sucessões culturais e (iii) feijão-caupi. As sucessões culturais foram compostas por cultivos agrícolas: milho - MI, sorgo - SO, algodão - AL, mamona - MN e girassol - GI; leguminosas: crotalária juncea - CJ, crotalária spectabilis - CS, feijão-de-porco - FP, guandu anão - GA, lab-lab - LA e mucuna-preta - MP e mucuna-anã - MA. Constaram ainda como tratamentos: parcelas com feijão-caupi sem…
Advisors/Committee Members: Assunção, Iraildes Pereira, CPF:54209021415, ASSUNÇÃO, I. P., Monteiro, Jean Herllington Araújo, CPF:76037240310, http://lattes.cnpq.br/4682041470293369, Muniz, Maria de Fátima Silva, CPF:22270477472, MUNIZ, M. F. S., Noronha, Marissonia de Araujo, CPF:74697145453, NORONHA, M. A..
Subjects/Keywords: Feijão-de-corda; Vigna unguiculata (L.); Fusarium oxysporum f. SP.; Tracheiphilum; Sucessão de cultura; Vigna unguiculata (L.); Fusarium oxysporum f.sp. tracheiphilum; Sucessões culturais; CNPQ::CIENCIAS AGRARIAS::AGRONOMIA
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Silva, W. C. d. (2011). Influência de sucessões de cultivos na severidade da murcha-de-fusário do caupi. (Masters Thesis). Universidade Federal de Alagoas. Retrieved from http://www.repositorio.ufal.br/handle/riufal/260
Chicago Manual of Style (16th Edition):
Silva, Wellington Costa da. “Influência de sucessões de cultivos na severidade da murcha-de-fusário do caupi.” 2011. Masters Thesis, Universidade Federal de Alagoas. Accessed January 22, 2021.
http://www.repositorio.ufal.br/handle/riufal/260.
MLA Handbook (7th Edition):
Silva, Wellington Costa da. “Influência de sucessões de cultivos na severidade da murcha-de-fusário do caupi.” 2011. Web. 22 Jan 2021.
Vancouver:
Silva WCd. Influência de sucessões de cultivos na severidade da murcha-de-fusário do caupi. [Internet] [Masters thesis]. Universidade Federal de Alagoas; 2011. [cited 2021 Jan 22].
Available from: http://www.repositorio.ufal.br/handle/riufal/260.
Council of Science Editors:
Silva WCd. Influência de sucessões de cultivos na severidade da murcha-de-fusário do caupi. [Masters Thesis]. Universidade Federal de Alagoas; 2011. Available from: http://www.repositorio.ufal.br/handle/riufal/260
17.
Renata de Freitas Ferreira Mohallem.
Hidróxido de cálcio (Ca(OH)2) e bactérias heterofermentativas como aditivos em silagens de cana-de-açúcar (Saccharum officinarum L.) para alimentação de ruminantes.
Degree: 2009, Federal University of Uberlândia
URL: http://www.bdtd.ufu.br//tde_busca/arquivo.php?codArquivo=3055
► O objetivo neste trabalho foi estudar as características de fermentação e qualidade nutricional das silagens de cana-de-açúcar, variedade IAC 862480, ensilada pura (tratamento controle-T1), com…
(more)
▼ O objetivo neste trabalho foi estudar as características de fermentação e qualidade nutricional das silagens de cana-de-açúcar, variedade IAC 862480, ensilada pura (tratamento controle-T1), com inoculante bacteriano/enzimático (Propionibacterium sp e enzimas amilolíticas- T2), inoculadas com bactérias heteroláticas (Lactobacillus buchneri- T3), ou tratadas com hidróxido de cálcio (Ca (OH)2) (inclusão de 0,8%- T4, 1,3%-T5 e 1,8%-T6 a massa verde). Avaliou-se a composição químico bromatológica, pH, ácidos graxos voláteis, etanol, nitrogênio amoniacal, digestibilidade in vitro e recuperação de matéria seca (RMS) num delineamento estatístico inteiramente casualisado composto de 6 tratamentos e três repetições cada. Os tratamentos T2 e T3 apresentaram desempenho semelhante ao T1 para todas as variáveis da composição bromatológica das silagens. Silagens contendo aditivos alcalinos (Ca (OH)2) foram mais eficientes na redução dos componentes da parede celular da cana-de-açúcar em relação ao T1, melhorando a DIVMS. Ao avaliar a RMS e as perdas fermentativas no processo de ensilagem, verificou-se mais uma vez muita semelhança do T1 e com a silagem T2, exceto o teor de etanol que foi menor em T2. Fato que não indica superioridade desta silagem em relação ao controle, uma vez que as RMS e DIVMS foram consideradas iguais estatisticamente ao T1. Silagens inoculadas com L. buchneri- T3 reduziram o teor de etanol e apresentaram boa RMS, mas não superaram os resultados apresentados pelos tratamentos com hidróxido de cálcio. Os tratamentos T4, T5 e T6 foram eficientes em controlar a fermentação alcoólica, associada a menor perda de MS e produção controlada de ácidos orgânicos semelhante aos teores relatados na literatura.
The objective of this study was to evaluate the effects of biological and chemical additives on the fermentative characteristics and nutritional quality of sugarcane (IAC 862480) silages. The trial was carried out in a completely randomized experimental design with factorial scheme of six treatments and three replicates per treatment. The treatments were based on the sugarcane silage additive: heterolactic bacteria (Lactobacillus buchneri), bacteria + enzyme (Propionibacterium sp associated with amylolytic enzymes), 0,8% Ca(OH)2, 1,3% Ca(OH)2, 1,8% Ca(OH)2 and crude sugarcane silage (control treatment). The treatments with Propionibacterium sp and amylolytic enzymes and with L. buchneri had bromatological results similar to the control treatment. The Propionibacterium sp and amylolytic enzymes silages showed lower ethanol levels when compared to the crude sugarcane silage. However, this fact does not indicate the superiority of Propionibacterium sp additive compared to control, since the dry matter recovery and the dry matter in vitro digestibility did not differed statically(P>0,05) from the control treatment. Silages inoculated with L. buchneri reduced the level of ethanol and showed good dry matter recovery, but did not surpass the results presented by treatments with hydrated lime. Silages with alkaline…
Advisors/Committee Members: Edmundo Benedetti, Evandro de Abreu Fernandes, Anael Araújo Santos Júnior.
Subjects/Keywords: Hidróxido de cálcio; Hidrólise; Cana-de-açúcar; MEDICINA VETERINARIA; Ruminante - Nutrição; Ruminante - Alimentação e rações; Calcium hydroxide; Hydrolysis; Inoculants; L. buchneri; Silage; Sugarcane; Silagem; Propionibacterium sp; Buchneri; Inoculante, L
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Mohallem, R. d. F. F. (2009). Hidróxido de cálcio (Ca(OH)2) e bactérias heterofermentativas como aditivos em silagens de cana-de-açúcar (Saccharum officinarum L.) para alimentação de ruminantes. (Thesis). Federal University of Uberlândia. Retrieved from http://www.bdtd.ufu.br//tde_busca/arquivo.php?codArquivo=3055
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Mohallem, Renata de Freitas Ferreira. “Hidróxido de cálcio (Ca(OH)2) e bactérias heterofermentativas como aditivos em silagens de cana-de-açúcar (Saccharum officinarum L.) para alimentação de ruminantes.” 2009. Thesis, Federal University of Uberlândia. Accessed January 22, 2021.
http://www.bdtd.ufu.br//tde_busca/arquivo.php?codArquivo=3055.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Mohallem, Renata de Freitas Ferreira. “Hidróxido de cálcio (Ca(OH)2) e bactérias heterofermentativas como aditivos em silagens de cana-de-açúcar (Saccharum officinarum L.) para alimentação de ruminantes.” 2009. Web. 22 Jan 2021.
Vancouver:
Mohallem RdFF. Hidróxido de cálcio (Ca(OH)2) e bactérias heterofermentativas como aditivos em silagens de cana-de-açúcar (Saccharum officinarum L.) para alimentação de ruminantes. [Internet] [Thesis]. Federal University of Uberlândia; 2009. [cited 2021 Jan 22].
Available from: http://www.bdtd.ufu.br//tde_busca/arquivo.php?codArquivo=3055.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Mohallem RdFF. Hidróxido de cálcio (Ca(OH)2) e bactérias heterofermentativas como aditivos em silagens de cana-de-açúcar (Saccharum officinarum L.) para alimentação de ruminantes. [Thesis]. Federal University of Uberlândia; 2009. Available from: http://www.bdtd.ufu.br//tde_busca/arquivo.php?codArquivo=3055
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Illinois – Urbana-Champaign
18.
Ilinca, Ingrid L.
Repr??sentations de la noblesse dans le roman fran??ais (1789-1848).
Degree: PhD, 0304, 2010, University of Illinois – Urbana-Champaign
URL: http://hdl.handle.net/2142/14575
► The French nobility is considered as a class defeated by the bourgeoisie and irrelevant within the capitalist economy. This widespread view fails to explain the…
(more)
▼ The French nobility is considered as a class defeated by the bourgeoisie and irrelevant within the capitalist economy. This widespread view fails to explain the vivid presence of the nobles in the 19th century cultural production. A phenomenological analysis of five novels (
L?????migr??, by S??
nac de Meilhan, Delphine, by Germaine de Sta??
l,
L???interdiction, Une double famille, and B??atrix, by Honor?? de Balzac) allows me to define a flexible model on which I base a study of nobility representations between 1789 and 1848. This model is organized around the following aspects: heredity and the idea of biological superiority, family and matrimonial practices, individual vs. lineage, education and savoir-faire, forms of sociability, (non)conformity to the norms, interpretation of signs and appearances, political engagements, equality vs. inequality, interaction with other social groups.
Advisors/Committee Members: Mortimer, Armine Kotin (advisor), Talbot, Emile J. (advisor), Mortimer, Armine Kotin (Committee Chair), Talbot, Emile J. (committee member), Mathy, Jean-Philippe (committee member), Fresco, Karen L. (committee member).
Subjects/Keywords: French literature; representations of nobility; S??nac de Meilhan; Germaine de Sta??l; Honor?? de Balzac; L'??migr??; Delphine; L'interdiction; Une double famille; B??atrix
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Ilinca, I. L. (2010). Repr??sentations de la noblesse dans le roman fran??ais (1789-1848). (Doctoral Dissertation). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/14575
Chicago Manual of Style (16th Edition):
Ilinca, Ingrid L. “Repr??sentations de la noblesse dans le roman fran??ais (1789-1848).” 2010. Doctoral Dissertation, University of Illinois – Urbana-Champaign. Accessed January 22, 2021.
http://hdl.handle.net/2142/14575.
MLA Handbook (7th Edition):
Ilinca, Ingrid L. “Repr??sentations de la noblesse dans le roman fran??ais (1789-1848).” 2010. Web. 22 Jan 2021.
Vancouver:
Ilinca IL. Repr??sentations de la noblesse dans le roman fran??ais (1789-1848). [Internet] [Doctoral dissertation]. University of Illinois – Urbana-Champaign; 2010. [cited 2021 Jan 22].
Available from: http://hdl.handle.net/2142/14575.
Council of Science Editors:
Ilinca IL. Repr??sentations de la noblesse dans le roman fran??ais (1789-1848). [Doctoral Dissertation]. University of Illinois – Urbana-Champaign; 2010. Available from: http://hdl.handle.net/2142/14575
19.
Sandoval, Jonathan E.
Characterization of the C. elegans nascent polypeptide associated complex (NAC) function under stress.
Degree: 2015, James Madison University
URL: https://commons.lib.jmu.edu/master201019/56
► The nascent polypeptide-associated complex (NAC) is a highly conserved heterodimer known to play an important role in protein folding and localization during metazoan development. Evidence…
(more)
▼ The nascent polypeptide-associated complex (
NAC) is a highly conserved heterodimer known to play an important role in protein folding and localization during metazoan development. Evidence in different model systems indicates that removal of either subunit of the
NAC, i.e. α- or β-
NAC, is sufficient to generate misfolded protein stress in the endoplasmic reticulum (ER), resulting in the activation of the ER-specific unfolded protein response (UPR). What is not yet understood is the nature of the UPR depending on which subunit of the
NAC is depleted. My research is focused on characterizing the specific UPR outcomes induced upon depletion of either α- or β-
NAC during misfolded protein stress in the ER. Assessment of UPR outcomes revealed that depletion of the C. elegans
NAC homologues icd-1/
NAC and icd-2/
NAC shared unique responses relative to the subunit depleted. Specifically, depletion of ICD-1 led to increased ER specific chaperone expression and robust attenuation of protein synthesis when compared to depletion of ICD-2. Along with managing protein homeostasis during ER stress, I also found that specific components of the
NAC and UPR actively contribute to cell differentiation programs, e.g. embryos depleted of ICD-1 displayed altered neuronal marker expression during ER stress, while other cell-type specific markers remained unchanged. These results suggest the individual subunits of the C. elegans
NAC are functional when unbound and contribute differentially to the activation of the UPR when one subunit is in excess relative to the other. Such findings may provide insights into the pathology of diseases such as Alzheimer’s, in which the 1:1 stoichiometry of the
NAC subunits is disrupted.
Advisors/Committee Members: Timothy Alan Bloss.
Subjects/Keywords: NAC; ER stress; cell stress; Cell Biology
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Sandoval, J. E. (2015). Characterization of the C. elegans nascent polypeptide associated complex (NAC) function under stress. (Masters Thesis). James Madison University. Retrieved from https://commons.lib.jmu.edu/master201019/56
Chicago Manual of Style (16th Edition):
Sandoval, Jonathan E. “Characterization of the C. elegans nascent polypeptide associated complex (NAC) function under stress.” 2015. Masters Thesis, James Madison University. Accessed January 22, 2021.
https://commons.lib.jmu.edu/master201019/56.
MLA Handbook (7th Edition):
Sandoval, Jonathan E. “Characterization of the C. elegans nascent polypeptide associated complex (NAC) function under stress.” 2015. Web. 22 Jan 2021.
Vancouver:
Sandoval JE. Characterization of the C. elegans nascent polypeptide associated complex (NAC) function under stress. [Internet] [Masters thesis]. James Madison University; 2015. [cited 2021 Jan 22].
Available from: https://commons.lib.jmu.edu/master201019/56.
Council of Science Editors:
Sandoval JE. Characterization of the C. elegans nascent polypeptide associated complex (NAC) function under stress. [Masters Thesis]. James Madison University; 2015. Available from: https://commons.lib.jmu.edu/master201019/56

Universidade Federal de Sergipe
20.
Cândida Regina de Oliveira Vasconcelos.
AVALIAÇÃO DE NÍVEIS SÉRICOS DE PACIENTES COM LEISHMANIOSE VISCERAL TRATADOS COM N-ACETIL-L-CISTEÍNA (NAC) E ANTIMONIAL PENTAVALENTE.
Degree: 2011, Universidade Federal de Sergipe
URL: http://bdtd.ufs.br/tde_busca/arquivo.php?codArquivo=666
► Para que a quimioterapia possa resultar em cura, é importante que o sistema imune tenha condições e estímulos necessários ao desenvolvimento do perfil de citocinas…
(more)
▼ Para que a quimioterapia possa resultar em cura, é importante que o sistema imune tenha condições e estímulos necessários ao desenvolvimento do perfil de citocinas adequado à resistência à doença e ao combate do agente etiológico. Estudos demonstram que o N-acetil-
L-cisteína (
NAC), uma substância antioxidante, contriubi para a imunoregulação de determinadas doenças. Assim, o objetivo deste trabalho foi avaliar os níveis séricos dos pacientes quanto à ação adjuvante do N-acetil-
L-cisteína (
NAC) na quimioterapia da leishmaniose visceral humana, feita com antimônio pentavalente. A partir de um estudo de intervenção, tipo ensaio clínico, cego, randomizado, foram investigados 60 pacientes do Hospital Universitário com diagnóstico positivo para leishmaniose visceral aguda. Esses pacientes foram distribuídos em dois grupos de 30: Grupo Estudo que fez uso do antimônio pentavalente dose padrão complementado com o N-acetil-
L-cisteína (
NAC) e o Grupo Controle - que fez uso apenas do antimônio dose padrão. Este trabalho foi aprovado pelo comitê de ética em pesquisa da UFS sob número CAAE 0151.0.107.000-07. Os pacientes selecionados e randomizados foram avaliados quanto aos parâmetros laboratoriais. Para avaliar as taxas de citocinas dos pacientes, foram realizadas dosagens dos níveis séricos de IFN-γ, TNF-α, IL-10, IL-12p40 e IL-12p70, sendo também dosada a molécula sCD40L antes, durante e após o tratamento, com uso do analisador LUMINEX 100. Os resultados sugerem que a adição do
NAC ao tratamento convencional melhora as taxas das citocinas dos pacientes, sobretudo a diminuição dos níveis séricos de IL-10, IL-12p40 e na elevação de sDC40L. Este estudo mostrou que, apesar de ambos os grupos apresentarem-se curados no último dia do tratamento, o grupo estudo desenvolveu uma resposta indicativa de cura mais precocemente, sugerindo que o
NAC tenha atuado de forma adjuvante ao antimônio pentavalente, sendo proposto ainda o uso da molecula sCD40L como um marcador prognóstico para a leishmaniose visceral.
Advisors/Committee Members: Roque Pacheco de Almeida.
Subjects/Keywords: Leishmaniose visceral; NAC; níveis séricos; CIENCIAS DA SAUDE; Leishmaniasis, NAC; levels serum
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Vasconcelos, C. R. d. O. (2011). AVALIAÇÃO DE NÍVEIS SÉRICOS DE PACIENTES COM LEISHMANIOSE VISCERAL TRATADOS COM N-ACETIL-L-CISTEÍNA (NAC) E ANTIMONIAL PENTAVALENTE. (Thesis). Universidade Federal de Sergipe. Retrieved from http://bdtd.ufs.br/tde_busca/arquivo.php?codArquivo=666
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Vasconcelos, Cândida Regina de Oliveira. “AVALIAÇÃO DE NÍVEIS SÉRICOS DE PACIENTES COM LEISHMANIOSE VISCERAL TRATADOS COM N-ACETIL-L-CISTEÍNA (NAC) E ANTIMONIAL PENTAVALENTE.” 2011. Thesis, Universidade Federal de Sergipe. Accessed January 22, 2021.
http://bdtd.ufs.br/tde_busca/arquivo.php?codArquivo=666.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Vasconcelos, Cândida Regina de Oliveira. “AVALIAÇÃO DE NÍVEIS SÉRICOS DE PACIENTES COM LEISHMANIOSE VISCERAL TRATADOS COM N-ACETIL-L-CISTEÍNA (NAC) E ANTIMONIAL PENTAVALENTE.” 2011. Web. 22 Jan 2021.
Vancouver:
Vasconcelos CRdO. AVALIAÇÃO DE NÍVEIS SÉRICOS DE PACIENTES COM LEISHMANIOSE VISCERAL TRATADOS COM N-ACETIL-L-CISTEÍNA (NAC) E ANTIMONIAL PENTAVALENTE. [Internet] [Thesis]. Universidade Federal de Sergipe; 2011. [cited 2021 Jan 22].
Available from: http://bdtd.ufs.br/tde_busca/arquivo.php?codArquivo=666.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Vasconcelos CRdO. AVALIAÇÃO DE NÍVEIS SÉRICOS DE PACIENTES COM LEISHMANIOSE VISCERAL TRATADOS COM N-ACETIL-L-CISTEÍNA (NAC) E ANTIMONIAL PENTAVALENTE. [Thesis]. Universidade Federal de Sergipe; 2011. Available from: http://bdtd.ufs.br/tde_busca/arquivo.php?codArquivo=666
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Vienna
21.
Heinrich, Alexander.
Influence of indirubin-3'-monoxime on redox systems in PDGF-activated vascular smooth muscle cells.
Degree: 2010, University of Vienna
URL: http://othes.univie.ac.at/8326/
Untersucht wurde der Einfluss von Indirubin-3´-monoxime auf den Level an freien Sauerstoffradikalen in PDGF aktivierten glatten Gefäßmuskelzellen. Ausserdem wurden frühere Ergebnisse, welche den Einfluss von Indirubin-3´-monoxime auf verschiedene intrazelluläre Signalwege untersuchten, wiederholt.
Subjects/Keywords: 42.15 Zellbiologie; 44.41 Pharmazeutische Biologie; glatte Gefäßmuskelzellen / Indirubin / NAC; VSMC / Indirubin / NAC
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
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APA (6th Edition):
Heinrich, A. (2010). Influence of indirubin-3'-monoxime on redox systems in PDGF-activated vascular smooth muscle cells. (Thesis). University of Vienna. Retrieved from http://othes.univie.ac.at/8326/
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Heinrich, Alexander. “Influence of indirubin-3'-monoxime on redox systems in PDGF-activated vascular smooth muscle cells.” 2010. Thesis, University of Vienna. Accessed January 22, 2021.
http://othes.univie.ac.at/8326/.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Heinrich, Alexander. “Influence of indirubin-3'-monoxime on redox systems in PDGF-activated vascular smooth muscle cells.” 2010. Web. 22 Jan 2021.
Vancouver:
Heinrich A. Influence of indirubin-3'-monoxime on redox systems in PDGF-activated vascular smooth muscle cells. [Internet] [Thesis]. University of Vienna; 2010. [cited 2021 Jan 22].
Available from: http://othes.univie.ac.at/8326/.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Heinrich A. Influence of indirubin-3'-monoxime on redox systems in PDGF-activated vascular smooth muscle cells. [Thesis]. University of Vienna; 2010. Available from: http://othes.univie.ac.at/8326/
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
22.
Kazmierczak, Theophile.
Identification de nouveaux régulateurs de la sénescence nodositaire chez Medicago truncatula : Identification of new regulatory factors involved in nodule senescence in Medicago truncatula.
Degree: Docteur es, Biologie, 2016, Université Paris-Saclay (ComUE)
URL: http://www.theses.fr/2016SACLS080
► La sénescence constitue la dernière étape du cycle de vie de certains organes des plantes. Elle permet leur dégradation tout en réallouant les constituants des…
(more)
▼ La sénescence constitue la dernière étape du cycle de vie de certains organes des plantes. Elle permet leur dégradation tout en réallouant les constituants des tissus sénescents vers d’autres organes. Dans le contexte de la nodulation symbiotique fixatrice d’azote entre certaines plantes légumineuses et des bactéries rhizobia, un processus de sénescence a été décrit. Cependant, les connaissances sur les mécanismes de régulation de la sénescence des nodosités symbiotiques sont limitées. Au sein du laboratoire, le facteur de transcription MtNAC969 a été identifié comme un régulateur de la sénescence des nodosités. L'objectif de cette thèse est d'identifier et de caractériser de nouveaux régulateurs de la sénescence de l'organe symbiotique. Nous avons développé : (i) une approche visant à identifier des facteurs de transcription corégulés avec MtNAC969 ou avec une cystéine protéase MtCP6 utilisée comme marqueur de la sénescence des nodosités ; et (ii), une approche avec "à priori" se focalisant sur la fonction des différentes voies de signalisation des cytokinines. Cette thèse a permis d'identifier deux facteurs de transcription, MtbHLH107 et MtNAC009 et de décrypter le rôle des cytokinines dans la sénescence des nodosités. Cette thèse a permis d'identifier d'une part, deux nouveaux gènes potentiellement régulateurs de la sénescence nodositaire, MtbHLH107 et MtNAC009; et d’autre partde décrypter le rôle des cytokinines dans la sénescence de cet organe symbiotique.
Senescence is the last step of plant organ lifespan and allows their degradation in order to remobilize components from senescent tissues toward others organs. In the nitrogen fixing symbiosis nodulation occurring between legume plants and rhizobia bacteria, a senescence process has been described. However, limited knowledge about regulatory systems controlling senescence in the symbiotic nodule is available. In the laboratory, the MtNAC969 transcription factor was identified as a regulator of nodule senescence. The aim of this PhD project is to identify and characterize new regulatory factors involved in nodule senescence. We developed two independent approaches : (i) the identification of genes coregulated with MtNAC969 or a cystein protease MtCP6 used as nodule senescence marker ; and (ii), targeted approach focused on the role of cytokinin signaling pathways in nodule senescence. This project allowed us to identify two regulator transcription factors, MtbHLH107 and MtNAC009 ; and to decipher the cytokinin role in the senescence of the symbiotic organ. This PhD thesis allowed us to identify two new potential regulators of nodule senescence, MtbHLH107 and MtNAC009; and to decipher the role of cytokinins in the senescence of this symbiotic organ.
Advisors/Committee Members: Gruber, Véronique (thesis director).
Subjects/Keywords: Senescence; Symbiose; Biologie moléculaire; Nac tf; Senescence; Symbiosis; Molecular biologie; Nac tf
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Kazmierczak, T. (2016). Identification de nouveaux régulateurs de la sénescence nodositaire chez Medicago truncatula : Identification of new regulatory factors involved in nodule senescence in Medicago truncatula. (Doctoral Dissertation). Université Paris-Saclay (ComUE). Retrieved from http://www.theses.fr/2016SACLS080
Chicago Manual of Style (16th Edition):
Kazmierczak, Theophile. “Identification de nouveaux régulateurs de la sénescence nodositaire chez Medicago truncatula : Identification of new regulatory factors involved in nodule senescence in Medicago truncatula.” 2016. Doctoral Dissertation, Université Paris-Saclay (ComUE). Accessed January 22, 2021.
http://www.theses.fr/2016SACLS080.
MLA Handbook (7th Edition):
Kazmierczak, Theophile. “Identification de nouveaux régulateurs de la sénescence nodositaire chez Medicago truncatula : Identification of new regulatory factors involved in nodule senescence in Medicago truncatula.” 2016. Web. 22 Jan 2021.
Vancouver:
Kazmierczak T. Identification de nouveaux régulateurs de la sénescence nodositaire chez Medicago truncatula : Identification of new regulatory factors involved in nodule senescence in Medicago truncatula. [Internet] [Doctoral dissertation]. Université Paris-Saclay (ComUE); 2016. [cited 2021 Jan 22].
Available from: http://www.theses.fr/2016SACLS080.
Council of Science Editors:
Kazmierczak T. Identification de nouveaux régulateurs de la sénescence nodositaire chez Medicago truncatula : Identification of new regulatory factors involved in nodule senescence in Medicago truncatula. [Doctoral Dissertation]. Université Paris-Saclay (ComUE); 2016. Available from: http://www.theses.fr/2016SACLS080

Lithuanian University of Agriculture
23.
Šidlauskas,
Giedrius.
Lietuvos kiaunių populiacijų
kokybė.
Degree: Master, Forestry, 2013, Lithuanian University of Agriculture
URL: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2013~D_20130621_144121-01615
;
► Atlikus Lietuvoje gyvenančių kiaunių gausos ir sumedžiojimo analizę nustatyta, kad pastarąjį dešimtmetį Lietuvoje kasmet vidutiniškai sumedžiojama apie 500 kiaunių. Tendencija didėjanti. Iki šiol nežinoma kiek…
(more)
▼ Atlikus Lietuvoje gyvenančių kiaunių gausos
ir sumedžiojimo analizę nustatyta, kad pastarąjį dešimtmetį
Lietuvoje kasmet vidutiniškai sumedžiojama apie 500 kiaunių.
Tendencija didėjanti. Iki šiol nežinoma kiek kiaunių sumedžiojama
pagal atskiras jų rūšis. Naudojant du skirtingus amžiaus nustatymo
metodus, abiejų kiaunių rūšių (M. martes ir M. foina) pirmamečių
individų nustatyta daugiau nei suaugusių. Pirmamečių miškinės
kiaunės patelių buvo nustatyta 12,5 % daugiau nei pirmamečių
patinų. Nustatyta, kad abiejų kiaunių rūšių patinai buvo stambesni
už pateles, tačiau jų lytinis dimorfizmas nėra stipriai išreikštas.
Abiejų kiaunių rūšių patinai statistiškai patikimai skyrėsi tik
pagal kūno masės ir krūtinės apimties duomenis (p< 0,1). Ištyrus
Lietuvos kiaunių užsikrėtimą trichinelioze, konstatuota, kad 8,3
proc. kiaunių nustatyta Trichinella sp., o 1 g raumenų vidutiniškai
rasta 1 šio parazito lerva.
After the assessment of martens abundance
and hunting analysis stated that in past ten years in Lithuania the
hunted martens are 500. The hunting tendency and numbers are
growing. At this moment is unknown number about hunting different
species individually (M. martes & M. foina). In this population
first year specimens was dominating against adults. First year Pine
marten female in population was 12,5 % more than first year males.
Both species martens males were larger than females, but the sexual
dimorphism wasn’t strong . Both species males had two different
statistically positive features – body weight and chest size (p<
0,1). Investigated Lithuanian martens from trichinelosis was
determined that 8,3 % martens has Trichinella spp. and in 1g.
Muscle in average was found 1 this parasite
larvae.
Advisors/Committee Members: Stankevičiūtė, Jolanta (Master’s thesis supervisor), Špinkytė - Bačkaitienė, Renata (Master’s thesis reviewer), Pėtelis, Kęstutis (Master’s thesis reviewer).
Subjects/Keywords: Miškinė kiaunė (Martes martes L.)
akmeninė kiaunė (Martes foina Erxleben 177); Gausa; Morfometriniai
tyrimai; Amžiaus
struktūra; Lytinis
dimorfizmas; Martes martes (Martes martes L.)
Stone marten (Martes foina Erxleben 177); Population
structure; Morfometric
researches; Sexual
dimorphism; Trichinella
sp
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Šidlauskas,
Giedrius. (2013). Lietuvos kiaunių populiacijų
kokybė. (Masters Thesis). Lithuanian University of Agriculture. Retrieved from http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2013~D_20130621_144121-01615 ;
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
Chicago Manual of Style (16th Edition):
Šidlauskas,
Giedrius. “Lietuvos kiaunių populiacijų
kokybė.” 2013. Masters Thesis, Lithuanian University of Agriculture. Accessed January 22, 2021.
http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2013~D_20130621_144121-01615 ;.
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
MLA Handbook (7th Edition):
Šidlauskas,
Giedrius. “Lietuvos kiaunių populiacijų
kokybė.” 2013. Web. 22 Jan 2021.
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
Vancouver:
Šidlauskas,
Giedrius. Lietuvos kiaunių populiacijų
kokybė. [Internet] [Masters thesis]. Lithuanian University of Agriculture; 2013. [cited 2021 Jan 22].
Available from: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2013~D_20130621_144121-01615 ;.
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
Council of Science Editors:
Šidlauskas,
Giedrius. Lietuvos kiaunių populiacijų
kokybė. [Masters Thesis]. Lithuanian University of Agriculture; 2013. Available from: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2013~D_20130621_144121-01615 ;
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
24.
Tejada, Erik Cendel Saenz.
Caracterização do gene do Fator Transcricional 3 da RNA Polimerase B (btf3) de Trichoderma reesei e o efeito de seu nocaute sobre a expressão gênica no estresse por choque térmico.
Degree: PhD, Bioquímica, 2007, University of São Paulo
URL: http://www.teses.usp.br/teses/disponiveis/46/46131/tde-23102007-142152/
;
► A transcrição pela RNA polimerase II (RNA polimerase B) e a sínteses de proteínas são os mais importantes processos metabólicos em células eucarióticas, e estão…
(more)
▼ A transcrição pela RNA polimerase II (RNA polimerase B) e a sínteses de proteínas são os mais importantes processos metabólicos em células eucarióticas, e estão envolvidas no controle da expressão gênica. Trichoderma reesei foi utilizado como modelo de estudo para o desenvolvimento deste estudo. Este fungo filamentoso é um microrganismo que vem sendo utilizado por vários laboratórios no mundo para o estudo dos diversos processos biológicos básicos devido à sua grande importância biotecnológica. Foi estabelecido por nosso grupo de pesquisa um banco de dados ESTs (\"Expressed Sequence Tags\") para este microrganismo e, por meio da técnica de \"microarraysd̈e cDNAs, determinou-se a reposta transcricional de T. reesei em função da disponibilidade de oxigênio e glicose, assim como a alguns estresses ambientais. Com base nesses resultados foram escolhidos alguns transcritos afetados pela limitação de oxigênio, tais como o gene btf3. Este gene codifica para a proteína reguladora BTF3 (Fator Transcricional 3 da RNA polimerase B), muito conservada em eucariotos, envolvida na transcrição de vários promotores da classe II e que faz parte do complexo que se liga aos polipeptídios nascentes (NAC). Com o intuito de estudar a funcionalidade do gene btf3 em condições normais e em choque térmico foi realizada uma análise transcricional comparativa em larga escala da cepa selvagem de T. reesei QM9414 e do mutante nocaute do gene btf3. A expressão de aproximadamente 2.000 genes foi analisada, por meio de \"microarrays\", em células submetidas ao estresse por choque térmico produzido pelo incremento da temperatura de cultura a 40°C. O nocaute do gene btf3 produziu o incremento da expressão dos genes das vias metabólicas primárias (ND4 e FBA), da defesa celular (DnaJ, HSP70 e RCI) e da síntese de proteínas (eIF2); enquanto que reprimiu genes da estrutura celular (HFBII) e da síntese de RNA (ATF21). No choque térmico, genes que codificam para proteínas associadas com a defesa celular, como as chaperonas Hsp70 e DnaJ, tiveram sua expressão induzida enquanto que proteínas associadas à divisão celular, como histonas e septina B, e à síntese de proteínas, como as proteínas ribossomais, foram reprimidas em ambas as cepas como resultado do estresse. Os resultados obtidos na análise por \"microarrayf̈oram validados através de PCR quantitativo em tempo real (qPCR). Estes resultados sugerem que BTF3 possa atuar como repressor de alguns genes transcritos pela RNA polimerase II.
Transcription by RNA polymerase II (RNA polymerase B) and protein synthesis are the most important metabolic processes in eukaryotic cells, and they are involved in the control of gene expression. Trichoderma reesei was used as model of study for the development of this study. This filamentous fungus is a microorganism that has been used by some laboratories around the world for the study of diverse basic biological questions due to its great biotechnological importance. We had established a data base of ESTs (Expressed Sequence Tags) for this…
Advisors/Committee Members: El Dorry, Hamza Fahmi Ali.
Subjects/Keywords: BTF3; BTF3; Choque térmico; Expressão gênica; Fungos; Fungus; Gene expression; Heat shock; NAC; NAC; Trichoderma reesei; Trichoderma reesei
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Tejada, E. C. S. (2007). Caracterização do gene do Fator Transcricional 3 da RNA Polimerase B (btf3) de Trichoderma reesei e o efeito de seu nocaute sobre a expressão gênica no estresse por choque térmico. (Doctoral Dissertation). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/46/46131/tde-23102007-142152/ ;
Chicago Manual of Style (16th Edition):
Tejada, Erik Cendel Saenz. “Caracterização do gene do Fator Transcricional 3 da RNA Polimerase B (btf3) de Trichoderma reesei e o efeito de seu nocaute sobre a expressão gênica no estresse por choque térmico.” 2007. Doctoral Dissertation, University of São Paulo. Accessed January 22, 2021.
http://www.teses.usp.br/teses/disponiveis/46/46131/tde-23102007-142152/ ;.
MLA Handbook (7th Edition):
Tejada, Erik Cendel Saenz. “Caracterização do gene do Fator Transcricional 3 da RNA Polimerase B (btf3) de Trichoderma reesei e o efeito de seu nocaute sobre a expressão gênica no estresse por choque térmico.” 2007. Web. 22 Jan 2021.
Vancouver:
Tejada ECS. Caracterização do gene do Fator Transcricional 3 da RNA Polimerase B (btf3) de Trichoderma reesei e o efeito de seu nocaute sobre a expressão gênica no estresse por choque térmico. [Internet] [Doctoral dissertation]. University of São Paulo; 2007. [cited 2021 Jan 22].
Available from: http://www.teses.usp.br/teses/disponiveis/46/46131/tde-23102007-142152/ ;.
Council of Science Editors:
Tejada ECS. Caracterização do gene do Fator Transcricional 3 da RNA Polimerase B (btf3) de Trichoderma reesei e o efeito de seu nocaute sobre a expressão gênica no estresse por choque térmico. [Doctoral Dissertation]. University of São Paulo; 2007. Available from: http://www.teses.usp.br/teses/disponiveis/46/46131/tde-23102007-142152/ ;
25.
Mani, Alexandra.
Η επίδραση της αντιοξειδωτικής προστασίας στον πνεύμονα σε πειραματικό μοντέλο χοίρου αιμορραγικής καταπληξίας: πειραματική μελέτη.
Degree: 2017, National and Kapodistrian University of Athens; Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών (ΕΚΠΑ)
URL: http://hdl.handle.net/10442/hedi/40643
► Uncompensated massive hemorrhage following traumatic injury is associated with significant morbidity and mortality, since acute severe hypovolemia and anemia lead to inadequate perfusion and oxygenation…
(more)
▼ Uncompensated massive hemorrhage following traumatic injury is associated with significant morbidity and mortality, since acute severe hypovolemia and anemia lead to inadequate perfusion and oxygenation of vital organs. Tissue hypoperfusion and hypoxia may cause irreversible cell damage and activation of a systemic inflammatory response. The latter is associated with the release of pathologically active substances, such as cytokines, reactive oxygen species, nitric oxide and may progress to multiple-organ dysfunction or even failure. Free radical production during hemorrhagic shock gives rise to increased oxidative stress.The aim of the present study was to investigate the pulmonary oxidative stress and possible protective effect of N-Acetylcysteine (NAC) and desferoxamine (DFX) in a porcine model subjected to hemorrhagic shock.Twenty-one pigs were randomly allocated to Group-A (sham, n=5), Group-B (fluid resuscitation, n=8) and Group-C (fluid, NAC and DFX resuscitation, n=8). Groups B and C were subjected to a 40-min shock period induced by liver trauma, followed by a 60-min resuscitation period. During shock, the mean arterial pressure (MAP) was maintained at 30-40mmHg. Resuscitation consisted of crystalloids (35ml/kg) and colloids (18ml/kg) targeting to MAP normalization (baseline values±10%). Additionally, Group-C received pretreatment with NAC 200mg/kg plus DFX 2g as intravenous infusions. Thiobarbituric Acid Reactive Substances (TBARS), protein carbonyls and glutathione peroxidase (GPx) activity were determined in lung tissue homogenates. Also, histological examination of pulmonary tissue specimens was performed. TBARS were higher in Group-B than in Group-A or Group-C: 2.90±0.47, 0.57±0.10, 1.78±0.47 pmol/μg protein, respectively (p<0.05). Protein carbonyls content was higher in Group-B than in Group-A or Group-C: 3.22±0.68, 0.89±0.30, 1.95±0.54 nmol/mg protein, respectively (p<0.05). GPx activity did not differ significantly between the three groups (p>0.05). Lung histology was improved in Group-C versus Group-B, with less alveolar collapse, interstitial edema and inflammation. In conclusion, NAC plus DFX prevented the increase of pulmonary oxidative stress markers and protein damage after resuscitated hemorrhagic shock and had beneficial effect on lung histology. NAC/DFX combination may be used in the multimodal treatment of hemorrhagic shock, since it may significantly prevent free radical injury in the lung.
Η αιμορραγική καταπληξία σχετίζεται με σημαντική θνητότητα και θνησιμότητα, μιας και η οξεία και βαριά υπογκαιμία και αναιμία οδηγούν σε ανεπαρκή αιμάτωση και οξυγόνωση ζωτικών οργάνων. Η κυτταρική βλάβη και η ενεργοποίηση συστηματικής φλεγμονώδους αντίδρασης, που προκαλούνται, σχετίζονται με την έκλυση παθολογικά ενεργών ουσιών, όπως οι κυτοκίνες και δραστικές μορφές οξυγόνου. Η δημιουργία ελεύθερων ριζών κατά την αιμορραγική καταπληξία αυξάνει το οξειδωτικό στρες και καταλήγει στην εκδήλωση ανεπάρκειας πολλαπλών οργάνων. Σκοπός της παρούσας ερευνητικής πειραματικής μελέτης ήταν να εκτιμηθεί κατά…
Subjects/Keywords: Ν-ακετυλοκυστεϊνη (NAC); Δεσφεροξαμίνη; Αιμορραγική καταπληξία; Οξειδωτικό στρες; Πνεύμονας; N-acetylcysteine (NAC); Desferoxamine; Hemorrhagic shock; Oxidative stress; Lungs
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Mani, A. (2017). Η επίδραση της αντιοξειδωτικής προστασίας στον πνεύμονα σε πειραματικό μοντέλο χοίρου αιμορραγικής καταπληξίας: πειραματική μελέτη. (Thesis). National and Kapodistrian University of Athens; Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών (ΕΚΠΑ). Retrieved from http://hdl.handle.net/10442/hedi/40643
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Mani, Alexandra. “Η επίδραση της αντιοξειδωτικής προστασίας στον πνεύμονα σε πειραματικό μοντέλο χοίρου αιμορραγικής καταπληξίας: πειραματική μελέτη.” 2017. Thesis, National and Kapodistrian University of Athens; Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών (ΕΚΠΑ). Accessed January 22, 2021.
http://hdl.handle.net/10442/hedi/40643.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Mani, Alexandra. “Η επίδραση της αντιοξειδωτικής προστασίας στον πνεύμονα σε πειραματικό μοντέλο χοίρου αιμορραγικής καταπληξίας: πειραματική μελέτη.” 2017. Web. 22 Jan 2021.
Vancouver:
Mani A. Η επίδραση της αντιοξειδωτικής προστασίας στον πνεύμονα σε πειραματικό μοντέλο χοίρου αιμορραγικής καταπληξίας: πειραματική μελέτη. [Internet] [Thesis]. National and Kapodistrian University of Athens; Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών (ΕΚΠΑ); 2017. [cited 2021 Jan 22].
Available from: http://hdl.handle.net/10442/hedi/40643.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Mani A. Η επίδραση της αντιοξειδωτικής προστασίας στον πνεύμονα σε πειραματικό μοντέλο χοίρου αιμορραγικής καταπληξίας: πειραματική μελέτη. [Thesis]. National and Kapodistrian University of Athens; Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών (ΕΚΠΑ); 2017. Available from: http://hdl.handle.net/10442/hedi/40643
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universidade Estadual de Campinas
26.
Costa, Marcello Alves.
Avaliação dos eventos extremos de maré para os anos de 2002, 2003 e 2004, seus impactos e as alterações temporais (1987 - 2007) dos cenários da paisagem do município de Itanhaém - SP - Brasil: Evaluation of extreme tidal events for the years 2002, 2003 and 2004, its impacts and temporal changes (1987-2007) of the scenery of the city of Itanhaém - São Paulo - Brazil.
Degree: 2012, Universidade Estadual de Campinas
URL: http://repositorio.unicamp.br/jspui/handle/REPOSIP/287670
► Abstract: Discussions on the landscape, their scenarios through the ages, its dynamic behavior and integration of human activities with the physical environment in which they…
(more)
▼ Abstract: Discussions on the landscape, their scenarios through the ages, its dynamic behavior and integration of human activities with the physical environment in which they operate are of deep interest in various sciences thus seeking new ways to understand the present moment. Floods, floods, landslides, heavy rains and high tides have passed much in recent years to be part of our daily informational. Therefore, this work presents a proposal for a municipal scale analysis covering the events called extreme tides that can cause many problems for infrastructure such as flooding and coastal erosion, transforming the landscape. The analyzes proposed departed detection of extreme tidal events for the years 2002, 2003, 2004 and compared with lunar periods of neap and spring tides. Using the statistical technique of multiple linear regressions was evaluated on an annual scale and week preceding extreme events, the relations of Variation of Tide with extreme temperature, the speed of the wind, the rain and Relative Humidity. It was also analyzed the transformation of the landscape temporally with an interval of 20 years (1987 - 2007), compared to parameters - Land Use, Vegetation Index (NDVI) and the variations of temperature, where the results in analyzes showed suppression of natural areas, densification of the urban as well as an increase in temperature among years. The studies showed that the detected extreme tides are related to the El Nino event, where tides were observed in the range from 1.2 to 1.92 meters (exaggerated). The winds, humidity and temperature, although low correlation, are components that indicate the presence of frontal systems that deliver extreme variations. The high tides cause flooding and coastal erosion in vulnerable areas, which are in the process of higher urban density and the simulation results of extreme tide in the city of Itanhaém - São Paulo - Brazil indicated that the most affected areas are precisely the areas that most denser over the period monitored
Advisors/Committee Members: UNIVERSIDADE ESTADUAL DE CAMPINAS (CRUESP), Pereira, Sueli Yoshinaga, 1961- (advisor), Universidade Estadual de Campinas. Instituto de Geociências (institution), Programa de Pós-Graduação em Geociências (nameofprogram), Matias, Lindon Fonseca (committee member), Oliveira, Regina Célia de (committee member), Moraes, Elisabete Caria (committee member), Novo, Evlyn Marcia Leão de Moraes (committee member).
Subjects/Keywords: Mares - Itanhaém (SP); Costa - Erosão - Itanhaém (SP); Itanhaem (SP) - Inundações; Tides - Itanhaém (SP); Beach erosion - Itanhaém (SP); Itanhaém (SP) - Floods
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Costa, M. A. (2012). Avaliação dos eventos extremos de maré para os anos de 2002, 2003 e 2004, seus impactos e as alterações temporais (1987 - 2007) dos cenários da paisagem do município de Itanhaém - SP - Brasil: Evaluation of extreme tidal events for the years 2002, 2003 and 2004, its impacts and temporal changes (1987-2007) of the scenery of the city of Itanhaém - São Paulo - Brazil. (Thesis). Universidade Estadual de Campinas. Retrieved from http://repositorio.unicamp.br/jspui/handle/REPOSIP/287670
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Costa, Marcello Alves. “Avaliação dos eventos extremos de maré para os anos de 2002, 2003 e 2004, seus impactos e as alterações temporais (1987 - 2007) dos cenários da paisagem do município de Itanhaém - SP - Brasil: Evaluation of extreme tidal events for the years 2002, 2003 and 2004, its impacts and temporal changes (1987-2007) of the scenery of the city of Itanhaém - São Paulo - Brazil.” 2012. Thesis, Universidade Estadual de Campinas. Accessed January 22, 2021.
http://repositorio.unicamp.br/jspui/handle/REPOSIP/287670.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Costa, Marcello Alves. “Avaliação dos eventos extremos de maré para os anos de 2002, 2003 e 2004, seus impactos e as alterações temporais (1987 - 2007) dos cenários da paisagem do município de Itanhaém - SP - Brasil: Evaluation of extreme tidal events for the years 2002, 2003 and 2004, its impacts and temporal changes (1987-2007) of the scenery of the city of Itanhaém - São Paulo - Brazil.” 2012. Web. 22 Jan 2021.
Vancouver:
Costa MA. Avaliação dos eventos extremos de maré para os anos de 2002, 2003 e 2004, seus impactos e as alterações temporais (1987 - 2007) dos cenários da paisagem do município de Itanhaém - SP - Brasil: Evaluation of extreme tidal events for the years 2002, 2003 and 2004, its impacts and temporal changes (1987-2007) of the scenery of the city of Itanhaém - São Paulo - Brazil. [Internet] [Thesis]. Universidade Estadual de Campinas; 2012. [cited 2021 Jan 22].
Available from: http://repositorio.unicamp.br/jspui/handle/REPOSIP/287670.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Costa MA. Avaliação dos eventos extremos de maré para os anos de 2002, 2003 e 2004, seus impactos e as alterações temporais (1987 - 2007) dos cenários da paisagem do município de Itanhaém - SP - Brasil: Evaluation of extreme tidal events for the years 2002, 2003 and 2004, its impacts and temporal changes (1987-2007) of the scenery of the city of Itanhaém - São Paulo - Brazil. [Thesis]. Universidade Estadual de Campinas; 2012. Available from: http://repositorio.unicamp.br/jspui/handle/REPOSIP/287670
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Brno University of Technology
27.
Kostovová, Iveta.
Možnosti využití odpadních lipidů a glycerolu k produkci karotenoidů kvasinkami.: Potential use of waste lipid substrates and glycerol to production of carotenoids by yeasts.
Degree: 2019, Brno University of Technology
URL: http://hdl.handle.net/11012/811
► The aim of this study was use of lipid waste substrates and waste glycerol as carbon sources for red yeasts. Six yeast strains, namely Rhodotorula…
(more)
▼ The aim of this study was use of lipid waste substrates and waste glycerol as carbon sources for red yeasts. Six yeast strains, namely Rhodotorula glutinis, Rhodotorula rubra, Rhodotorula aurantiaca, Cystofilobasidium capitatum, Sporobolomyces roseus and Sporobolomyces shibatanus were used for cultivation. All studied yeast strains were able to utilize glycerol and rapeseed oil as a carbon source. Cultivation in oil medium was in most of strains accompanied by decreased production of carotenoids. Increased production of ergosterol, lycopene and biomass was observed in some strains only. Most of yeast strains cultivated in glycerol medium produced increased amount of biomass as well as carotenoids. The best producer of bi-omass and pigments was yeast strain Sporobolomyces roseus CCY 19-6-4 grown in medium containing glucose and glycerol in a 1:1 ratio.
Advisors/Committee Members: Márová, Ivana (advisor), Obruča, Stanislav (referee).
Subjects/Keywords: Karotenoidy; Rhodotorula sp.; Cystofilobasidium sp.; Sporobolomyces sp.; glycerol; olej.; Carotenoids; Rhodotorula sp.; Cystofilobasidium sp.; Sporobolomyces sp.; glycerol; oil
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Kostovová, I. (2019). Možnosti využití odpadních lipidů a glycerolu k produkci karotenoidů kvasinkami.: Potential use of waste lipid substrates and glycerol to production of carotenoids by yeasts. (Thesis). Brno University of Technology. Retrieved from http://hdl.handle.net/11012/811
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Kostovová, Iveta. “Možnosti využití odpadních lipidů a glycerolu k produkci karotenoidů kvasinkami.: Potential use of waste lipid substrates and glycerol to production of carotenoids by yeasts.” 2019. Thesis, Brno University of Technology. Accessed January 22, 2021.
http://hdl.handle.net/11012/811.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Kostovová, Iveta. “Možnosti využití odpadních lipidů a glycerolu k produkci karotenoidů kvasinkami.: Potential use of waste lipid substrates and glycerol to production of carotenoids by yeasts.” 2019. Web. 22 Jan 2021.
Vancouver:
Kostovová I. Možnosti využití odpadních lipidů a glycerolu k produkci karotenoidů kvasinkami.: Potential use of waste lipid substrates and glycerol to production of carotenoids by yeasts. [Internet] [Thesis]. Brno University of Technology; 2019. [cited 2021 Jan 22].
Available from: http://hdl.handle.net/11012/811.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Kostovová I. Možnosti využití odpadních lipidů a glycerolu k produkci karotenoidů kvasinkami.: Potential use of waste lipid substrates and glycerol to production of carotenoids by yeasts. [Thesis]. Brno University of Technology; 2019. Available from: http://hdl.handle.net/11012/811
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
28.
SILVA, Claudio Pereira da.
Uma proposta de agregação de informações de contexto para framework de segurança NAC
.
Degree: 2010, Universidade Federal de Pernambuco
URL: http://repositorio.ufpe.br/handle/123456789/2235
► Surgiu nos últimos anos a discussão sobre um framework de segurança que fosse capaz de suprir a necessidade de integração entre as diversas ferramentas de…
(more)
▼ Surgiu nos últimos anos a discussão sobre um framework de segurança que fosse capaz de
suprir a necessidade de integração entre as diversas ferramentas de segurança: o
NAC
(Network Access Control). Este framework chega em um momento onde a computação
converge para o emprego da computação ubíqua. Sendo assim, o objetivo deste trabalho é
propor informações de contexto que contribuirão com novas formas de análises ao framework
de segurança
NAC. Utilizamos métricas que mostram os contextos alterados durante
ataques a um dispositivo. Mostramos que é possível mapear estas alterações e com isso
mudar as regras de acesso à rede do dispositivo baseados nestas mudanças de contextos
Advisors/Committee Members: FERRAZ, Carlos André Guimarães (advisor).
Subjects/Keywords: Computação ciente de
contexto;
Computação ubíqua;
Framework NAC;
Segurança
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APA ·
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MLA ·
Vancouver ·
CSE |
Export
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Manager
APA (6th Edition):
SILVA, C. P. d. (2010). Uma proposta de agregação de informações de contexto para framework de segurança NAC
. (Thesis). Universidade Federal de Pernambuco. Retrieved from http://repositorio.ufpe.br/handle/123456789/2235
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
SILVA, Claudio Pereira da. “Uma proposta de agregação de informações de contexto para framework de segurança NAC
.” 2010. Thesis, Universidade Federal de Pernambuco. Accessed January 22, 2021.
http://repositorio.ufpe.br/handle/123456789/2235.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
SILVA, Claudio Pereira da. “Uma proposta de agregação de informações de contexto para framework de segurança NAC
.” 2010. Web. 22 Jan 2021.
Vancouver:
SILVA CPd. Uma proposta de agregação de informações de contexto para framework de segurança NAC
. [Internet] [Thesis]. Universidade Federal de Pernambuco; 2010. [cited 2021 Jan 22].
Available from: http://repositorio.ufpe.br/handle/123456789/2235.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
SILVA CPd. Uma proposta de agregação de informações de contexto para framework de segurança NAC
. [Thesis]. Universidade Federal de Pernambuco; 2010. Available from: http://repositorio.ufpe.br/handle/123456789/2235
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Michigan
29.
Best, Elaine Abby.
The nac gene of Klebsiella aerogenes.
Degree: PhD, Microbiology, 1988, University of Michigan
URL: http://hdl.handle.net/2027.42/128248
► In enteric bacteria, transcription of a large family of genes is regulated by the Nitrogen Regulatory (Ntr) System in response to the availability of nitrogen.…
(more)
▼ In enteric bacteria, transcription of a large family of genes is regulated by the Nitrogen Regulatory (Ntr) System in response to the availability of nitrogen. The isolation of insertion mutations in a gene called
nac demonstrates that control of several nitrogen-regulated genes by the Ntr System is mediated indirectly. K. aerogenes cells containing null mutations in
nac are unable to activate expression of hut (histidine utilization), put (proline utilization), and ure (urea utilization), or to repress formation of gdh (glutamate dehydrogenase), and gltB (glutamate synthase). These
nac null mutants are still able to regulate expression of glnA (glutamine synthetase), nar (nitrate reductase) and nif (nitrogen fixation), and are unaffected in the regulation of the Ntr System itself. Studies of K. aerogenes
nac mutants in which the E. coli lacZ gene is under control of the
nac promoter indicate that expression of
nac is regulated by the availability of nitrogen and by the Ntr System. A DNA fragment of approximately 13 kb containing the K. aerogenes
nac gene was cloned. Complementation studies performed using the cloned
nac gene and several independently derived
nac insertion mutants suggest that
nac modulates its own expression and that the
nac locus encodes at least two functions: one involved in the regulation of
nac target operons, the other involved in the regulation of
nac itself. Wild-type Salmonella typhimurium cells strongly resemble K. aerogenes
nac mutants. In wild-type S. typhimurium, operons such as glnA, which are regulated directly by the Ntr System, are activated in response to nitrogen limitation, but operons such as hut, which are indirectly regulated by Ntr control, are not. Introduction of a plasmid containing the K. aerogenes
nac gene into S. typhimurium allows S. typhimurium to activate hut expression during nitrogen-limited growth. Thus,
nac is either missing or defective in S. typhimurium.
Advisors/Committee Members: Bender, Robert A. (advisor), Clewell, Don B. (advisor).
Subjects/Keywords: Aerogenes; Gene; Klebsiella; Nac
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Best, E. A. (1988). The nac gene of Klebsiella aerogenes. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/128248
Chicago Manual of Style (16th Edition):
Best, Elaine Abby. “The nac gene of Klebsiella aerogenes.” 1988. Doctoral Dissertation, University of Michigan. Accessed January 22, 2021.
http://hdl.handle.net/2027.42/128248.
MLA Handbook (7th Edition):
Best, Elaine Abby. “The nac gene of Klebsiella aerogenes.” 1988. Web. 22 Jan 2021.
Vancouver:
Best EA. The nac gene of Klebsiella aerogenes. [Internet] [Doctoral dissertation]. University of Michigan; 1988. [cited 2021 Jan 22].
Available from: http://hdl.handle.net/2027.42/128248.
Council of Science Editors:
Best EA. The nac gene of Klebsiella aerogenes. [Doctoral Dissertation]. University of Michigan; 1988. Available from: http://hdl.handle.net/2027.42/128248

Texas A&M University
30.
Alvarado Chavez, Veria Ysabel.
Analysis of the Arabidopsis NAC gene superfamily in plant development.
Degree: PhD, Molecular and Enviromental Plant Sciences, 2009, Texas A&M University
URL: http://hdl.handle.net/1969.1/ETD-TAMU-2588
► There are a vast number of transcription factors that regulate plant growth and development. The NAC gene superfamily is one of the largest families of…
(more)
▼ There are a vast number of transcription factors that regulate plant growth and development. The
NAC gene superfamily is one of the largest families of transcription factors in the plant kingdom.
NAC gene expression profiles using Affymetrix ATH1 gene chips were obtained for different plant organs: heart embryo, mature embryo, leaf, root and flower.
NAC gene expression profiles proved to be very complex, except for one
NAC gene detected only in floral tissue, At1g61110. At1g61110 was shown to be specifically expressed in the anther tapetum of Arabidospis; therefore, its name was changed to TAPNAC. TAPNAC became the focus of our studies. We identified a tapnac T-DNA knockout (KO) line, SALK_069450. A molecular phenotype was observed. Several oligopeptide, sugar and metal transporters were differentially expressed. Coincidentally, a wheat
NAC gene, named TaNAM-B1 for its high sequence similarity to ATNAM, TAPNAC and At3g15510 was found to be involved in nutrient remobilization. PHOSPHOLIPASE Dα1 (PLDα1) was also found to be down-regulated in the tapnac KO. PLDα1 is an enzyme which hydrolyzes phospholipids that are part of tapetal cell membranes and tapetal lipid bodies. Once these tapetal cell structures are disrupted, the secretion of the compounds that form part of the pollen coat (i.e. proteins, flavonoids and lipids) into the anther locule is facilitated. Promoter deletion analysis using a GUS reporter and later GUS immuno-localization confirmed the findings of Wellmer and others. TAPNAC is a tapetal specific gene. The cis-regulatory sequence that enhances tapetal expression in the TAPNAC promoter was identified. The consensus motif TCGTGT increased tapetal expression of a GUS reporter gene, only when flanked by the TAPNAC minimal promoter region (-217 bp to +51 bp). In summary, TAPNAC transcription factor has been characterized and data indicates that it could play a role in nutrient remobilization from the tapetum to the pollen grains, particularly during late floral stages. Also, important information on tapetal specifcation cis-regulatory sequences was discovered. The consensus motif TCGTGT, present in TAPNAC promoter, was shown to enhance tapetal expression of a GUS reporter gene.
Advisors/Committee Members: Thomas, Terry (advisor), McKnight, Tom (committee member), Pepper, Alan (committee member), Shippen, Dorothy (committee member).
Subjects/Keywords: NAC genes; plant development; Arabidopsis
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Alvarado Chavez, V. Y. (2009). Analysis of the Arabidopsis NAC gene superfamily in plant development. (Doctoral Dissertation). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/ETD-TAMU-2588
Chicago Manual of Style (16th Edition):
Alvarado Chavez, Veria Ysabel. “Analysis of the Arabidopsis NAC gene superfamily in plant development.” 2009. Doctoral Dissertation, Texas A&M University. Accessed January 22, 2021.
http://hdl.handle.net/1969.1/ETD-TAMU-2588.
MLA Handbook (7th Edition):
Alvarado Chavez, Veria Ysabel. “Analysis of the Arabidopsis NAC gene superfamily in plant development.” 2009. Web. 22 Jan 2021.
Vancouver:
Alvarado Chavez VY. Analysis of the Arabidopsis NAC gene superfamily in plant development. [Internet] [Doctoral dissertation]. Texas A&M University; 2009. [cited 2021 Jan 22].
Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2588.
Council of Science Editors:
Alvarado Chavez VY. Analysis of the Arabidopsis NAC gene superfamily in plant development. [Doctoral Dissertation]. Texas A&M University; 2009. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2588
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